Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#1
Nick Shrine, Anna L Guyatt, A Mesut Erzurumluoglu, Victoria E Jackson, Brian D Hobbs, Carl A Melbourne, Chiara Batini, Katherine A Fawcett, Kijoung Song, Phuwanat Sakornsakolpat, Xingnan Li, Ruth Boxall, Nicola F Reeve, Ma'en Obeidat, Jing Hua Zhao, Matthias Wielscher, Stefan Weiss, Katherine A Kentistou, James P Cook, Benjamin B Sun, Jian Zhou, Jennie Hui, Stefan Karrasch, Medea Imboden, Sarah E Harris, Jonathan Marten, Stefan Enroth, Shona M Kerr, Ida Surakka, Veronique Vitart, Terho Lehtimäki, Richard J Allen, Per S Bakke, Terri H Beaty, Eugene R Bleecker, Yohan Bossé, Corry-Anke Brandsma, Zhengming Chen, James D Crapo, John Danesh, Dawn L DeMeo, Frank Dudbridge, Ralf Ewert, Christian Gieger, Amund Gulsvik, Anna L Hansell, Ke Hao, Joshua D Hoffman, John E Hokanson, Georg Homuth, Peter K Joshi, Philippe Joubert, Claudia Langenberg, Xuan Li, Liming Li, Kuang Lin, Lars Lind, Nicholas Locantore, Jian'an Luan, Anubha Mahajan, Joseph C Maranville, Alison Murray, David C Nickle, Richard Packer, Margaret M Parker, Megan L Paynton, David J Porteous, Dmitry Prokopenko, Dandi Qiao, Rajesh Rawal, Heiko Runz, Ian Sayers, Don D Sin, Blair H Smith, María Soler Artigas, David Sparrow, Ruth Tal-Singer, Paul R H J Timmers, Maarten Van den Berge, John C Whittaker, Prescott G Woodruff, Laura M Yerges-Armstrong, Olga G Troyanskaya, Olli T Raitakari, Mika Kähönen, Ozren Polašek, Ulf Gyllensten, Igor Rudan, Ian J Deary, Nicole M Probst-Hensch, Holger Schulz, Alan L James, James F Wilson, Beate Stubbe, Eleftheria Zeggini, Marjo-Riitta Jarvelin, Nick Wareham, Edwin K Silverman, Caroline Hayward, Andrew P Morris, Adam S Butterworth, Robert A Scott, Robin G Walters, Deborah A Meyers, Michael H Cho, David P Strachan, Ian P Hall, Martin D Tobin, Louise V Wain
No abstract text is available yet for this article.
April 19, 2024: Nature Genetics
#2
JOURNAL ARTICLE
Laura D Zambrano, Margaret M Newhams, Regina M Simeone, Amanda B Payne, Michael Wu, Amber O Orzel-Lockwood, Natasha B Halasa, Jemima M Calixte, Pia S Pannaraj, Kanokporn Mongkolrattanothai, Julie A Boom, Leila C Sahni, Satoshi Kamidani, Kathleen Chiotos, Melissa A Cameron, Aline B Maddux, Katherine Irby, Jennifer E Schuster, Elizabeth H Mack, Austin Biggs, Bria M Coates, Kelly N Michelson, Katherine E Bline, Ryan A Nofziger, Hillary Crandall, Charlotte V Hobbs, Shira J Gertz, Sabrina M Heidemann, Tamara T Bradford, Tracie C Walker, Stephanie P Schwartz, Mary Allen Staat, Samina S Bhumbra, Janet R Hume, Michele Kong, Melissa S Stockwell, Thomas J Connors, Melissa L Cullimore, Heidi R Flori, Emily R Levy, Natalie Z Cvijanovich, Matt S Zinter, Mia Maamari, Cindy Bowens, Danielle M Zerr, Judith A Guzman-Cottrill, Ivan Gonzalez, Angela P Campbell, Adrienne G Randolph
Pediatric COVID-19 vaccination is effective in preventing COVID-19-related hospitalization, but duration of protection of the original monovalent vaccine during SARS-CoV-2 Omicron predominance merits evaluation, particularly given low coverage with updated COVID-19 vaccines. During December 19, 2021-October 29, 2023, the Overcoming COVID-19 Network evaluated vaccine effectiveness (VE) of ≥2 original monovalent COVID-19 mRNA vaccine doses against COVID-19-related hospitalization and critical illness among U...
April 18, 2024: MMWR. Morbidity and Mortality Weekly Report
#3
JOURNAL ARTICLE
Gail Hayward, Sam Mort, Alastair D Hay, Michael Moore, Nicholas P B Thomas, Johanna Cook, Jared Robinson, Nicola Williams, Nicola Maeder, Rebecca Edeson, Marloes Franssen, Jenna Grabey, Margaret Glogowska, Yaling Yang, Julie Allen, Christopher C Butler
IMPORTANCE: Recurrent urinary tract infection (UTI) is a common debilitating condition in women, with limited prophylactic options. d-Mannose has shown promise in trials based in secondary care, but effectiveness in placebo-controlled studies and community settings has not been established. OBJECTIVE: To determine whether d-mannose taken for 6 months reduces the proportion of women with recurrent UTI experiencing a medically attended UTI. DESIGN, SETTING, AND PARTICIPANTS: This 2-group, double-blind randomized placebo-controlled trial took place across 99 primary care centers in the UK...
April 8, 2024: JAMA Internal Medicine
#4
JOURNAL ARTICLE
Margaret M Fisher, Andrew D Allen, Alexander D Jeffs, Patricia K Wellborn, Di Hu, J Megan M Patterson, Reid W Draeger
PURPOSE: Resection of the radial or ulnar slip of the flexor digitorum superficialis (FDS) tendon is a known treatment option for persistent trigger finger. Risk factors for undergoing FDS slip excision are unclear. We hypothesized that patients who underwent A1 pulley release with FDS slip excision secondary to persistent triggering would have a higher comorbidity burden compared to those receiving A1 pulley release alone. METHODS: We identified all adult patients who underwent A1 pulley release with FDS slip excision because of persistent triggering either intraoperatively or postoperatively from 2018 to 2023...
March 18, 2024: Journal of Hand Surgery
#5
JOURNAL ARTICLE
Margaret Shatara, Megan Blue, Joseph Stanek, Yin A Liu, Daniel M Prevedello, Pierre Giglio, Vinay K Puduvalli, Sharon L Gardner, Jeffrey C Allen, Kenneth K Wong, Marvin D Nelson, Floyd H Gilles, Roberta H Adams, Jasmine Pauly, Katrina O'Halloran, Ashley S Margol, Girish Dhall, Jonathan L Finlay
BACKGROUND: Patients with relapsed intracranial germinoma can achieve durable remission with standard chemotherapy regimens and/or reirradiation; however, innovative therapies are required for patients with relapsed and/or refractory intracranial nongerminomatous germ cell tumors (NGGCTs) due to their poor prognosis. Improved outcomes have been reported using reinduction chemotherapy to achieve minimal residual disease, followed by marrow-ablative chemotherapy (HDCx) with autologous hematopoietic progenitor cell rescue (AuHPCR)...
April 2024: Neuro-oncology Practice
#6
JOURNAL ARTICLE
Shireen Suliman, Margaret Allen, Tawanda Chivese, Angelique E de Rijk, Richard Koopmans, Karen D Könings
INTRODUCTION: The negative impact of medical training on trainee mental health continues to be a concern. Situated within a sociocultural milieu, Generation Z and Generation Y, defined by their highly involved parents and the widespread use of technology, currently dominate undergraduate and graduate medical education respectively. It is necessary to explore medical trainees' generational characteristics and job-related factors related to stress, burnout, depression, and resilience. This might provide different perspectives and potential solutions to medical trainees' mental health...
December 31, 2024: Medical Education Online
#7
JOURNAL ARTICLE
Beatriz Guillen-Guio, Megan L Paynton, Richard J Allen, Daniel P W Chin, Lauren J Donoghue, Amy Stockwell, Olivia C Leavy, Tamara Hernandez-Beeftink, Carl Reynolds, Paul Cullinan, Fernando Martinez, Helen L Booth, William A Fahy, Ian P Hall, Simon P Hart, Mike R Hill, Nik Hirani, Richard B Hubbard, Robin J McAnulty, Ann B Millar, Vidya Navaratnam, Eunice Oballa, Helen Parfrey, Gauri Saini, Ian Sayers, Martin D Tobin, Moira K B Whyte, Ayodeji Adegunsoye, Naftali Kaminski, Shwu-Fan Ma, Mary E Strek, Yingze Zhang, Tasha E Fingerlin, Maria Molina-Molina, Margaret Neighbors, X Rebecca Sheng, Justin M Oldham, Toby M Maher, Philip L Molyneaux, Carlos Flores, Imre Noth, David A Schwartz, Brian L Yaspan, R Gisli Jenkins, Louise V Wain, Edward J Hollox
INTRODUCTION: Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial pneumonia marked by progressive lung fibrosis and a poor prognosis. Recent studies have highlighted the potential role of infection in the pathogenesis of IPF, and a prior association of the HLA-DQB1 gene with idiopathic fibrotic interstitial pneumonia (including IPF) has been reported. Owing to the important role that the human leukocyte antigen (HLA) region plays in the immune response, here we evaluated if HLA genetic variation was associated specifically with IPF risk...
January 2024: ERJ Open Research
#8
JOURNAL ARTICLE
John S Kim, Yifei Sun, Pallavi Balte, Mary Cushman, Rebekah Boyle, Russell P Tracy, Linda M Styer, Taison D Bell, Michaela R Anderson, Norrina B Allen, Pamela J Schreiner, Russell P Bowler, David A Schwartz, Joyce S Lee, Vanessa Xanthakis, Margaret F Doyle, Elizabeth A Regan, Barry J Make, Alka M Kanaya, Sally E Wenzel, Josef Coresh, Carmen R Isasi, Laura M Raffield, Mitchell S V Elkind, Virginia J Howard, Victor E Ortega, Prescott Woodruff, Shelley A Cole, Joel M Henderson, Nicholas J Mantis, Monica M Parker, Ryan T Demmer, Elizabeth C Oelsner
This study investigates correlates of anti-S1 antibody response following COVID-19 vaccination in a U.S. population-based meta-cohort of adults participating in longstanding NIH-funded cohort studies. Anti-S1 antibodies were measured from dried blood spots collected between February 2021-August 2022 using Luminex-based microsphere immunoassays. Of 6245 participants, mean age was 73 years (range, 21-100), 58% were female, and 76% were non-Hispanic White. Nearly 52% of participants received the BNT162b2 vaccine and 48% received the mRNA-1273 vaccine...
February 19, 2024: Nature Communications
#9
Olivia C Leavy, Anne F Goemans, Amy D Stockwell, Richard J Allen, Beatriz Guillen-Guio, Tamara Hernandez-Beeftink, Ayodeji Adegunsoye, Helen L Booth, Paul Cullinan, William A Fahy, Tasha E Fingerlin, Harvinder S Virk, Ian P Hall, Simon P Hart, Mike R Hill, Nik Hirani, Richard B Hubbard, Naftali Kaminski, Shwu-Fan Ma, Robin J McAnulty, X Rebecca Sheng, Ann B Millar, Maria Molina-Molina, Vidya Navaratnam, Margaret Neighbors, Helen Parfrey, Gauri Saini, Ian Sayers, Mary E Strek, Martin D Tobin, Moira Kb Whyte, Yingze Zhang, Toby M Maher, Philip L Molyneaux, Justin M Oldham, Brian L Yaspan, Carlos Flores, Fernando Martinez, Carl J Reynolds, David A Schwartz, Imre Noth, R Gisli Jenkins, Louise V Wain
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a chronic lung condition that is more prevalent in males than females. The reasons for this are not fully understood, with differing environmental exposures due to historically sex-biased occupations, or diagnostic bias, being possible explanations. To date, over 20 independent genetic variants have been identified to be associated with IPF susceptibility, but these have been discovered when combining males and females. Our aim was to test for the presence of sex-specific associations with IPF susceptibility and assess whether there is a need to consider sex-specific effects when evaluating genetic risk in clinical prediction models for IPF...
January 15, 2024: medRxiv
#10
JOURNAL ARTICLE
Nicole Zhao, Allison M Cuthel, Owen Storms, Raina Zhang, Rebecca Liddicoat Yamarik, Jacob Hill, Regina Kaur, Kaitlyn Van Allen, Mara Flannery, Alex Chang, Frank Chung, Sumeet Randhawa, Isabel Castro Alvarez, Angela Young-Brinn, Constance L Kizzie-Gillett, Dawn Rosini, Eric D Isaacs, Ernest Hopkins, Garrett K Chan, Juanita Booker-Vaughns, Margaret Maguire, Martha Navarro, Neha Reddy Pidatala, Patrick Dunn, Pluscedia Williams, Robert Galvin, Romilla Batra, Sally Welsh, William Vaughan, Jean-Baptiste Bouillon-Minois, Corita R Grudzen
BACKGROUND: Involving patient and community stakeholders in clinical trials adds value by ensuring research prioritizes patient goals both in conduct of the study and application of the research. The use of stakeholder committees and their impact on the conduct of a multicenter clinical trial have been underreported clinically and academically. The aim of this study is to describe how Study Advisory Committee (SAC) recommendations were implemented throughout the Emergency Medicine Palliative Care Access (EMPallA) trial...
January 23, 2024: Research Involvement and Engagement
#11
JOURNAL ARTICLE
Kirsten Fagerli, Munkhchuluun Ulziibayar, Bujinlkham Suuri, Dashtseren Luvsantseren, Dorj Narangerel, Purevsuren Batsaikhan, Bilegtsaikhan Tsolmon, John de Campo, Margaret de Campo, Eileen M Dunne, Kristen E Allen, Anneke C Grobler, Cattram D Nguyen, Bradford D Gessner, Tuya Mungun, E Kim Mulholland, Claire von Mollendorf
BACKGROUND: Few studies have assessed the potential indirect effects of childhood pneumococcal conjugate vaccine (PCV) programs on the adult pneumonia burden in resource-limited settings. We evaluated the impact of childhood PCV13 immunisation on adult all-cause pneumonia following a phased program introduction from 2016. METHODS: We conducted a time-series analysis to assess changes in pneumonia hospitalisation incidence at four district hospitals in Mongolia. Adults (≥18 years) that met the clinical case definition for all-cause pneumonia were enrolled...
March 2024: The Lancet Regional Health. Western Pacific
#12
JOURNAL ARTICLE
Courtney H Van Houtven, Valerie A Smith, Katherine E M Miller, Theodore S Z Berkowitz, Megan Shepherd-Banigan, Tyler Hein, Lauren S Penney, Kelli D Allen, Margaret Kabat, Timothy Jobin, S Nicole Hastings
Disabled Veterans commonly experience pain. The Program of Comprehensive Assistance for Family Caregivers (PCAFC) provides training, a stipend, and services to family caregivers of eligible Veterans to support their caregiving role. We compared ascertainment of veteran pain and pain treatment through health care encounters and medications (pain indicators) of participants (treated group) and non-participants (comparison group) using inverse probability treatment weights. Modeled results show that the proportion of Veterans with a pain indicator in the first year post-application was higher than that pre-application for both groups...
December 7, 2023: Medical Care Research and Review: MCRR
#13
JOURNAL ARTICLE
Akihisa Sakai, Tudor Borza, Ali Antar, Ethan Richmond, Glenn O Allen, Margaret Knoedler, Christopher Manakas, Wei Huang, Daniel Gralnek, Matthew D Grimes
OBJECTIVE: To determine the incidence of incidental prostate cancer detection (iPCa) after holmium laser enucleation of the prostate (HoLEP). The published rate of iPCa after HoLEP is widely variable from 7-23% and we aim to define preoperative risk factors for iPCa to inform risk adjusted preoperative evaluation for prostate cancer. METHODS: Consecutive patients undergoing HoLEP from 2018-2022 were included and comprehensive clinical data abstracted from a prospectively maintained database...
December 1, 2023: Urology
#14
JOURNAL ARTICLE
Margaret A Nagai-Singer, Mackenzie K Woolls, Katerina Leedy, Alissa Hendricks-Wenger, Rebecca M Brock, Sheryl Coutermarsh-Ott, Tamalika Paul, Holly A Morrison, Khan M Imran, Juselyn D Tupik, Endia J Fletcher, David A Brown, Irving C Allen
Prior studies have defined multiple, but inconsistent, roles for the enigmatic pattern recognition receptor NLRX1 in regulating several cancer-associated biological functions. In this study, we explore the role of NLRX1 in the highly metastatic murine 4T1 mammary tumor model. We describe a functional dichotomy of NLRX1 between two different cellular contexts: expression in healthy host cells versus expression in the 4T1 tumor cells. Using Nlrx1-/- mice engrafted with 4T1 tumors, we demonstrate that NLRX1 functions as a tumor suppressor when expressed in the host cells...
November 1, 2023: Journal of Immunology
#15
JOURNAL ARTICLE
Vivienne H Au, Lauren E Miller, Margaret B Mitchell, Andrew R Larson, Derrick T Lin, Allen L Feng, Jeremy D Richmon
IMPORTANCE: While there has been an increased understanding of the impact of visible neck scars in some patients with certain diseases, this has not yet been explored in the HPV+ OPSCC population. OBJECTIVE: To understand patients' perception of their scar and the impact on their quality of life (QOL) at least 6 months after neck dissection (ND) for HPV+ oropharyngeal squamous cell carcinoma (OPSCC). DESIGN, SETTING, AND PARTICIPANTS: In this retrospective case-control study, patients who underwent primary transoral robotic surgery (TORS) and ND for HPV+ OPSCC between 2016 and 2021 at a single tertiary care center were identified...
October 12, 2023: American Journal of Otolaryngology
#16
JOURNAL ARTICLE
Faith Chesire, Margaret Kaseje, Marlyn Ochieng, Benson Ngatia, Michael Mugisha, Ronald Ssenyonga, Matt Oxman, Allen Nsangi, Daniel Semakula, Rose James Christopher, Laetitia Nyirazinyoye, Astrid Dahlgren, Simon Lewin, Nelson K Sewankambo, Sarah Rosenbaum, Andrew D Oxman
AIM: There is an overabundance of claims about the advantages and disadvantages of health interventions. People need to be able to appraise the reliability of these claims. The aim of this two-arm cluster-randomized trial was to evaluate the Informed Health Choices secondary school intervention designed to teach students to assess claims about the effects of health actions and make informed decisions. METHODS: We conducted the trial among students from 80 secondary schools in five subcounties in Kenya...
September 21, 2023: Journal of Evidence-based Medicine
#17
JOURNAL ARTICLE
Michael Mugisha, Laetitia Nyirazinyoye, Clarisse Marie Claudine Simbi, Faith Chesire, Ronald Senyonga, Matt Oxman, Allen Nsangi, Daniel Semakula, Christopher James Rose, Jenny Moberg, Astrid Dahlgren, Margaret Kaseje, Simon Lewin, Nelson K Sewankambo, Sarah Rosenbaum, Andrew D Oxman
AIM: The aim of this trial was to evaluate the effects of the Informed Health Choices intervention on the ability of students in Rwandan to think critically and make Informed Health Choices. METHODS: We conducted a two-arm cluster-randomized trial in 84 lower secondary schools from 10 districts representing five provinces of Rwanda. We used stratified randomization to allocate schools to the intervention or control. One class in each intervention school had ten 40-min lessons taught by a trained teacher in addition to the usual curriculum...
September 21, 2023: Journal of Evidence-based Medicine
#18
JOURNAL ARTICLE
Faith Chesire, Michael Mugisha, Ronald Ssenyonga, Christopher J Rose, Allen Nsangi, Margaret Kaseje, Nelson K Sewankambo, Matt Oxman, Sarah E Rosenbaum, Jenny Moberg, Astrid Dahlgren, Simon Lewin, Andrew D Oxman
AIM: The aim of this prospective meta-analysis was to synthesize the results of three cluster-randomized trials of an intervention designed to teach lower-secondary school students (age 14-16) to think critically about health choices. METHODS: We conducted the trials in Kenya, Rwanda, and Uganda. The intervention included a 2- to 3-day teacher training workshop, digital resources, and ten 40-min lessons. The lessons focused on nine key concepts. We did not intervene in control schools...
September 21, 2023: Journal of Evidence-based Medicine
#19
JOURNAL ARTICLE
Ronald Ssenyonga, Andrew D Oxman, Esther Nakyejwe, Faith Chesire, Michael Mugisha, Allen Nsangi, Daniel Semakula, Matt Oxman, Christopher James Rose, Sarah E Rosenbaum, Jenny Moberg, Margaret Kaseje, Laetitia Nyirazinyoye, Astrid Dahlgren, Simon Lewin, Nelson K Sewankambo
AIM: The aim was to evaluate the effect of the Informed Health Choices (IHC) educational intervention on secondary students' ability to assess health-related claims and make informed choices. METHODS: In a cluster-randomized trial, we randomized 80 secondary schools (students aged 13-17 years) in Uganda to the intervention or control (usual curriculum). The intervention included a 2-day teacher training workshop, 10 lessons accessed online by teachers and delivered in one school term...
September 19, 2023: Journal of Evidence-based Medicine
#20
JOURNAL ARTICLE
Cole Buchanan, Collen Buchanan, Maeveen Riordan, Jessica Byrd, Margaret Schulte, Wendy M Kohrt, Amrut V Ambardekar, Larry A Allen, Gene Wolfel, Justin Lawley, Benjamin D Levine, William K Cornwell
BACKGROUND: Patients with heart failure with reduced ejection fraction (HFrEF) have persistent impairments in functional capacity after continuous-flow left ventricular assist device (CF-LVAD) implantation. OBJECTIVES: This study aims to characterize longitudinal changes in exercise hemodynamics and functional capacity among patients with HFrEF before and after CF-LVAD implantation. METHODS: Ten patients underwent 3 invasive cardiopulmonary exercise tests on upright cycle ergometry with pulmonary artery catheterization: 1) Visit 1 before CF-LVAD implantation; 2) Visit 2 after device implantation with CF-LVAD pump speed held constant at baseline speed; and 3) Visit 3 with increases in pump speed during exercise (median: 1,050 rpm [IQR: 750-1,150 rpm] and 220 rpm [IQR: 120-220 rpm] for Heartmate 3 and Heartware VAD, respectively)...
August 7, 2023: JACC. Heart Failure
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
