keyword
MENU ▼
Read by QxMD icon Read
search

Microflora

keyword
https://www.readbyqxmd.com/read/28935866/mulberry-leaf-alleviates-streptozotocin-induced-diabetic-rats-by-attenuating-nefa-signaling-and-modulating-intestinal-microflora
#1
Yao Sheng, Shujuan Zheng, Tianshi Ma, Chuanhai Zhang, Xiaoqun Ou, Xiaoyun He, Wentao Xu, Kunlun Huang
Improvement of hyperglycemia through dietotherapy/herbal remedy is an effective approach to treating diabetes. In this study, mulberry leaf, famous for silkworm's special food and therapeutic value without any side effects, alleviated diabetes by attenuating NEFA signaling and modulating intestinal microflora. Mulberry leaf treatment significantly reduce fasting blood-glucose and HbA1c, ameliorate the blood lipid profile and improve insulin resistance in streptozotocin-induced diabetic rats. Mechanistically, we found that mulberry leaf inhibited NEFA signaling by reducing downstream signaling in the NEFA pathway, further verified by reduced PKC and improved cellular energy homeostasis based on restored expression of PGC-1α, AK2, OXPHOS and adiponectin...
September 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28928534/suitability-of-the-probiotic-lactic-acid-bacteria-strains-as-the-starter-cultures-in-unripe-cornelian-cherry-cornus-mas-l-fermentation
#2
Agata Czyżowska, Alicja Z Kucharska, Agnieszka Nowak, Anna Sokół-Łętowska, Ilona Motyl, Narcyz Piórecki
This study examines the influence of lactic acid fermentation on iridoid and polyphenolic compounds in unripe Cornus mas L. fruits. Fermentation was carried out at room temperature over 6 weeks. Eight versions of the fermentation process were conducted: with inoculation by microflora isolated from black olives, Lb. brevis 18 M, Lb. casei 0919, Lb. paracasei 920, Lb. rhamnosus 0900, Lb. rhamnosus 0908, and spontaneous fermentation with and without summer savory (Satureja hortensis). The polyphenolic compounds, iridoids and antioxidant activities were examined in the products obtained...
August 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28923170/prebiotics-in-the-management-of-components-of-the-metabolic-syndrome
#3
REVIEW
Sarah O'Connor, Sarah Chouinard-Castonguay, Claudia Gagnon, Iwona Rudkowska
Components of the metabolic syndrome (MetS), including abdominal obesity, low-grade chronic systemic inflammation, altered glucose metabolism, dyslipidemia and high blood pressure, are major threats to healthy aging in modern societies. The connection between MetS components and gut microflora is now acknowledged and multiple therapeutic strategies have been proposed to change the composition of the gut microbiota in order to promote optimal metabolic health. Prebiotics have the ability to favour growth of beneficial bacteria, especially short-chain fatty-acids (SCFA) producers...
October 2017: Maturitas
https://www.readbyqxmd.com/read/28917709/in-vitro-interactions-of-acanthamoeba-castellanii-neff-and-vibrio-harveyi
#4
María Reyes-Batlle, Alberto J Martín-Rodríguez, Atteneri López-Arencibia, Ines Sifaoui, Aitor Rizo Liendo, Carlos J Bethencourt Estrella, Ana B García Méndez, Olfa Chiboub, Soumaya Hajaji, Basilio Valladares, Enrique Martínez-Carretero, José E Piñero, Jacob Lorenzo-Morales
Free-living amoebae (FLA) are opportunistic protozoa widely distributed in the environment. They are frequently found in water and soil samples, but they have also been reported to be associated with bacterial human pathogens such as Legionella spp. Campylobacter spp or Vibrio cholerae among others. Including within Vibrio spp. V. harveyi (Johnson and Shunk, 1936) is a bioluminescent marine bacteria which has been found swimming freely in tropical marine waters, being part of the stomach and intestine microflora of marine animals, and as both a primary and opportunistic pathogen of marine animals...
September 13, 2017: Experimental Parasitology
https://www.readbyqxmd.com/read/28914862/-liver-diseases-the-pathogenetic-role-of-the-gut-microbiome-and-the-potential-of-treatment-for-its-modulation
#5
K A Aitbaev, I T Murkamilov, V V Fomin
The paper gives an update on the role of the gut microbiome (GM) in the development of nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, alcoholic liver disease, liver cirrhosis (LC), and its complications, such as hepatic encephalopathy (HE) and hepatocellular carcinoma (HCC), and discusses the possibilities of its correction with prebiotics, probiotics, synbiotics, antibiotics, and fecal microbiota transplantation (FMT). The pathophysiology of the liver diseases in question demonstrates some common features that are characterized by pathogenic changes in the composition of the gastrointestinal tract microflora, by intestinal barrier impairments, by development of endotoxemia, by increased liver expression of proinflammatory factors, and by development of liver inflammation...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28914067/-drugs-and-dosage-forms-as-risk-factors-for-dental-caries
#6
Petra Bořilová Linhartová, Lydie Izakovičová Hollá
Dental caries is a multifactorial disease which, despite a series of preventive measures, remains the most common infectious disease worldwide. Susceptibility or resistance to caries may be a result of the presence of risk or protective factors, genetic predisposition, inappropriate lifestyle associated with education, behavioural and socioeconomic factors. The aim of this review is to highlight the risks associated with the use of some drugs and dosage forms in relation to the formation and development of dental caries...
2017: Ceská a Slovenská Farmacie
https://www.readbyqxmd.com/read/28905280/enzymatic-synthesis-of-fucose-containing-galacto-oligosaccharides-using-%C3%AE-galactosidase-and-identification-of-novel-disaccharide-structures
#7
Anne Usvalampi, Hannu Maaheimo, Olli Tossavainen, Alexander D Frey
Fucosylated oligosaccharides have an important role in maintaining a healthy immune system and homeostatic gut microflora. This study employed a commercial β-galactosidase in the production of fucose-containing galacto-oligosaccharides (fGOS) from lactose and fucose. The production was optimized using experiment design and optimal conditions for a batch production in 3-liter scale. The reaction product was analyzed and the produced galactose-fucose disaccharides were purified. The structures of these disaccharides were determined using NMR and it was verified that one major product with the structure Galβ1-3Fuc and two minor products with the structures Galβ1-4Fuc and Galβ1-2Fuc were formed...
September 13, 2017: Glycoconjugate Journal
https://www.readbyqxmd.com/read/28901909/usefulness-of-%C3%A3-la-carte-antigens-for-bird-fancier-s-lung-serodiagnosis-total-dropping-extract-and-or-dropping-s-microflora-antigens
#8
Adeline Rouzet, Gabriel Reboux, Jean-Charles Dalphin, Paul De Vuyst, Audrey Laboissière, Benoit Valot, Laurence Millon, Sandrine Roussel
Bird fancier's lung (BFL) is a pulmonary disease caused by inhalation of avian proteins. The involvement of the microorganisms of droppings has been assumed in the past and this idea still persists today. Our study aimed to compare by immunoprecipitation assay the detection of antibodies against both droppings and microorganisms in the sera of patients (n=15) and asymptomatic exposed controls (n=18). We found that 14/15 BFL patients had negative serological results for isolated microorganisms of the droppings, only one positive against Enterobacter sakasakii...
September 13, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28895387/chaenomeles-%C3%A2-health-promoting-benefits
#9
Katarzyna Watychowicz, Katarzyna Janda, Karolina Jakubczyk, Jolanta Wolska
Chaenomeles is a genus of deciduous spiny in the family of Rosaceae (Pomoideae subfamily). For centuries, the plant was used for a treatment of anemia, rheumatism, gout and cardiovascular diseases. The chemical composition studies of Chaenomeles showed the presence of many biologically active compounds, such as: phenolic compounds, organic acids, terpenoids, alcohols, ketones or aldehydes. Fruit of Chaenomeles has the largest applying potential due to extensive use of medicinal and high concentration of vitamin C...
2017: Roczniki Państwowego Zakładu Higieny
https://www.readbyqxmd.com/read/28892902/effects-of-different-contraceptive-methods-on-cervico-vaginal-cytology
#10
Khushboo Garg, Anjali Khare, Rani Bansal, Sangeeta Sharma, Neha Chaudhary
INTRODUCTION: The vaginal flora of healthy adult women of reproductive age group constitutes predominantly Lactobacilli which inhibits the growth of other microorganisms (by maintaining acidic pH). The vaginal microflora is altered in favour of anaerobes in women using Intra Uterine Contraceptive Device (IUCD). Also, it can cause morphologic changes in both squamous and endocervical columnar cells. Similarly, the prevalence of vaginal lactobacilli is reduced among women using diaphragm-spermicide or spermicide alone...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28889756/occurrence-of-vancomycin-resistant-staphylococcus-aureus-in-the-oral-cavity-of-patients-with-dental-caries
#11
Sajith Vellappally, Darshan Devang Divakar, Abdulaziz Abdullah Al Kheraif, Ravikumar Ramakrishnaiah, Amer Alqahtani, M H N Dalati, Sukumaran Anil, Aftab Ahmed Khan, P R Harikrishna Varma
Oral streptococci are the major group of microbes isolated from oral microflora. They represent frequent pathogens of infective endocarditis (IE), and it is assumed that in most of the cases oral streptococci are acquired via mucosa layer of oral cavity. Staphylococcus aureus is also frequently isolated from IE as it accounts for 20%-30% of all cases. Vancomycin has been the most reliable therapeutic agent against infections caused by methicillin-resistant S. aureus (MRSA). The main objective of this study was to examine the occurrence of S...
September 11, 2017: Acta Microbiologica et Immunologica Hungarica
https://www.readbyqxmd.com/read/28884952/soluble-dietary-fiber-reduces-trimethylamine-metabolism-via-gut-microbiota-and-co-regulates-host-ampk-pathways
#12
Qian Li, Tao Wu, Rui Liu, Min Zhang, Ruijun Wang
SCOPE: Evidence from animal experiments and clinical medicine suggest that high dietary fiber intake, followed by gut microbiota-mediated fermentation, decreases trimethylamine (TMA) metabolism, the mechanism of which, however, remains unclear. The objective of this analysis was to evaluate, using mice fed with red meat, the effects of soluble dietary fiber (SDF) intervention on TMA metabolism. METHODS AND RESULTS: Low- or high-dose soluble dietary fiber (SDF) from natural wheat bran (LN and HN, low- and high-dose natural SDF), fermented wheat bran (LF and HF, low- and high-dose fermented SDF), and steam-exploded wheat bran (LE and HE, low- and high-dose exploded SDF groups) were used to examine whether SDF interventions in mice fed with red meat can alter TMA and trimethylamine N-oxide (TMAO) metabolism by gut microbial communities in a diet-specific manner...
September 8, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28884389/microbial-communities-in-pesticide-contaminated-soils-in-kyrgyzstan-and-bioremediation-possibilities
#13
Tinatin Doolotkeldieva, Maxabat Konurbaeva, Saykal Bobusheva
In Kyrgyzstan, many former storehouses and dump sites for obsolete pesticides exist. In 2009/2010, an inventory and assessment of these sites including risks of environmental hazard has been conducted by FAO and the World Bank. Monitoring revealed high concentration of pesticides listed as persistent organic pollutants (POPs). The purpose of this research was to study the microbial structural complexes of the pesticide-contaminated soils in these dumping zones, and to search for and select microorganism's destructors with cytochrome P450 genes for pesticide degradation...
September 7, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28882791/effects-of-organic-acids-and-essential-oils-blend-on-growth-gut-microbiota-immune-response-and-disease-resistance-of-pacific-white-shrimp-litopenaeus-vannamei-against-vibrio-parahaemolyticus
#14
Wangquan He, Samad Rahimnejad, Ling Wang, Kai Song, Kangle Lu, Chunxiao Zhang
An 8-week feeding trial was undertaken to evaluate supplemental effects of AviPlus(®) (AP), a blend of organic acids [citric acid, 25%; sorbic acid, 16.7%] and essential oils [thymol, 1.7%; vanillin, 1.0%], on growth, gut microbiota, innate immunity and disease resistance of Pacific white shrimp (Litopenaeus vannamei) against Vibrio parahaemolyticus. A basal experimental diet was formulated and supplemented with 0, 0.3, 0.6, 0.9 and 1.2 g kg(-1) AP to produce five test diets (Con, AP0.3, AP0.6, AP0.9 and AP1...
September 4, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28882639/effects-of-residual-levels-of-tetracycline-on-the-barrier-functions-of-human-intestinal-epithelial-cells
#15
Kuppan Gokulan, Carl E Cerniglia, Charles Thomas, Silvia A Pineiro, Sangeeta Khare
Tetracyclines are frequently used in food-producing animals to treat, control, and prevent microbial diseases. Concerns are raised regarding the effects of residual levels of tetracycline, which may be present in the food supply, for emergence of drug-resistance and transfer of antibiotic-resistance gene in intestinal microbiota. In contrast, no information is available regarding the possible effects of residual tetracycline on the gastrointestinal epithelial layer barrier-disruption. This study investigates the outcome of tetracycline treatment on intestinal epithelial cells integrity...
September 4, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28878691/spontaneous-preterm-birth-is-associated-with-differential-expression-of-vaginal-metabolites-by-lactobacilli-dominated-microflora
#16
Graham P Stafford, Jennifer L Parker, Emmanuel Amabebe, James Kistler, Steven Reynolds, Victoria Stern, Martyn Paley, Dilly O C Anumba
A major challenge in preventing preterm birth (PTB) is identifying women at greatest risk. This pilot study prospectively examined the differences in vaginal microbiota and metabolite profiles of women who delivered prematurely compared to their term counterparts in a cohort of asymptomatic (studied at 20-22, n = 80; and 26-28 weeks, n = 41) and symptomatic women (studied at 24-36 weeks, n = 37). Using 16S rRNA sequencing, the vaginal microbiota from cervicovaginal fluid samples was characterized into five Community State Types (CST) dominated by Lactobacillus spp...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28877970/the-transcriptional-response-of-candida%C3%A2-albicans-to-weak-organic-acids-carbon-source-and-mig1%C3%A2-inactivation-unveils-a-role-for-hgt16-in-mediating-the-fungistatic-effect-of-acetic-acid
#17
Fabien Cottier, Alrina Shin Min Tan, Marina Yurieva, Webber Liao, Josephine Lum, Michael Poidinger, Francesca Zolezzi, Norman Pavelka
Candida albicans is a resident fungus of the human intestinal microflora. Commonly isolated at low abundance in healthy people, C. albicans outcompetes local microbiota during candidiasis episodes. Under normal conditions, members of the human gastrointestinal microbiota were shown to keep C. albicans colonization under control. By releasing weak organic acids (WOAs), bacteria are able to moderate yeast growth. This mechanism displayed a synergistic effect in vitro with the absence of glucose in medium of culture, which underline the complex interaction that C...
September 6, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28874750/amixicile-a-novel-strategy-for-targeting-oral-anaerobic-pathogens
#18
Justin A Hutcherson, Kathryn M Sinclair, Benjamin R Belvin, Qin Gui, Paul S Hoffman, Janina P Lewis
The oral microflora is composed of both health-promoting as well as disease-initiating bacteria. Many of the disease-initiating bacteria are anaerobic and include organisms such as Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, and Tannerella forsythia. Here we investigated a novel therapeutic, amixicile, that targets pyruvate:ferredoxin oxidoreductase (PFOR), a major metabolic enzyme involved in energy generation through oxidative decarboxylation of pyruvate. PFOR is present in these anaerobic pathogenic bacteria and thus we hypothesized that amixicile would effectively inhibit their growth...
September 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28872093/-research-progress-of-trimethylamine-n-oxide-in-the-pathogenesis-of-atherosclerosis
#19
Huahua He, Xinfu Lian, Zhiqun Tang
Trimethylamine-N-oxide (TMAO), metabolites of the intestinal microflora, is a newly discovered risk factor for cardiovascular disease. The intestinal flora converted choline and L-carnitine into trimethylamine in the food. Trimethylamine is oxidized to TMAO in liver enzymes. Lowering TMA can stimulate macrophages to reverse cholesterol transport and inhibit atherogenesis. TMAO poietin-monooxygenase 3 (FMO3) is a tool for cholesterol metabolism and reverse cholesterol transpor, lowering FMO3 can slow the gallbladder's secretion of bile, delay intestinal absorption of cholesterol, and limit the synthesis of oxidized cholesterol and cholesterol esters...
August 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28871718/clostridium-difficile-infection-a-current-therapeutic-and-epidemiological-problem
#20
Aleksandra Mirecka
Clostridium difficile (CD) is the most common etiologic agent of antibiotic-associated diarrhea. The number of infections has increased dramatically in the last decade. Although the diseases caused by CD are mostly related to health care and antibiotic therapy, some are community-acquired cases. This article explains the pathogenesis of this microorganism, pointing to depletion of intestinal microflora diversity and the inadequate response of the immune system as an important factor predisposing the development of CD infection...
2017: Przegla̧d Epidemiologiczny
keyword
keyword
29035
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"