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https://www.readbyqxmd.com/read/27897087/nuclear-imaging-of-thrombosis-in-small-animal
#1
Marie-Cécile Valéra, Bernard Payrastre, Olivier Lairez
Thromboembolic disorders are a major cause of morbidity and mortality worldwide. The progress in noninvasive imaging techniques has led to the development of radionuclide imaging based on SPECT and PET approaches to observe molecular and cellular processes that may underlie the onset and progression of disease. The advantages of using normal and genetically modified small animal research have spurred the development of dedicated small animal imaging systems. Animal models of venous and arterial thrombosis are largely used and have improved our understanding of the etiology and pathogenesis of thrombosis...
November 29, 2016: Platelets
https://www.readbyqxmd.com/read/27887817/is-there-a-role-for-regenerative-medicine-in-chronic-rhinosinusitis-with-nasal-polyps
#2
EDITORIAL
Fabiana C P Valera, Leandra M Endam, Badr Ibrahim, Emmanuelle Brochiero, Martin Y Desrosiers
No abstract text is available yet for this article.
November 2, 2016: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/27871135/fire-modifies-the-phylogenetic-structure-of-soil-bacterial-co-occurrence-networks
#3
Eduardo Pérez-Valera, Marta Goberna, Karoline Faust, Jeroen Raes, Carlos García, Miguel Verdú
Fire alters ecosystems by changing the composition and community structure of soil microbes. The phylogenetic structure of a community provides clues about its main assembling mechanisms. While environmental filtering tends to reduce the community phylogenetic diversity by selecting for functionally (and hence phylogenetically) similar species, processes like competitive exclusion by limiting similarity tend to increase it by preventing the coexistence of functionally (and phylogenetically) similar species...
November 21, 2016: Environmental Microbiology
https://www.readbyqxmd.com/read/27860075/comparison-between-urine-culture-profile-and-morphology-classification-using-fluorescence-parameters-of-the-sysmex-uf-1000i-urine-flow-cytometer
#4
Gemma Jiménez-Guerra, Víctor Heras-Cañas, María Dolores Valera-Arcas, Javier Rodríguez-Grangér, José María Navarro, José Gutiérrez-Fernández
AIMS: To determine the usefulness of the fluorescence parameters generated by Sysmex UF-1000i flow cytometer for the rapid diagnosis of urinary tract infection by bacilli or cocci. METHODS AND RESULTS: Urine samples (n=1924) were studied by culture and microbiology and subsequently by cytometry, using BACT Morph software and considering forward scattered light- (FSC) and fluorescent light scatter (FLH) fluorescence parameters. BACT-Morph software showed moderate diagnostic accuracy (78...
November 18, 2016: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/27856733/spontaneous-default-network-activity-reflects-behavioral-variability-independent-of-mind-wandering
#5
Aaron Kucyi, Michael Esterman, Clay S Riley, Eve M Valera
The brain's default mode network (DMN) is highly active during wakeful rest when people are not overtly engaged with a sensory stimulus or externally oriented task. In multiple contexts, increased spontaneous DMN activity has been associated with self-reported episodes of mind-wandering, or thoughts that are unrelated to the present sensory environment. Mind-wandering characterizes much of waking life and is often associated with error-prone, variable behavior. However, increased spontaneous DMN activity has also been reliably associated with stable, rather than variable, behavior...
November 29, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27845811/life-review-when-course-assignments-change-lives
#6
Valera Dee Smith Lester, Donald Dee Kautz
No abstract text is available yet for this article.
November 15, 2016: Journal of Gerontological Nursing
https://www.readbyqxmd.com/read/27831545/neuroimaging-findings-in-mowat-wilson-syndrome-a-study-of-54-patients
#7
Livia Garavelli, Ivan Ivanovski, Stefano Giuseppe Caraffi, Daniela Santodirocco, Marzia Pollazzon, Duccio Maria Cordelli, Ebtesam Abdalla, Patrizia Accorsi, Margaret P Adam, Chiara Baldo, Allan Bayat, Elga Belligni, Federico Bonvicini, Jeroen Breckpot, Bert Callewaert, Guido Cocchi, Goran Cuturilo, Koenraad Devriendt, Mary Beth Dinulos, Olivera Djuric, Roberta Epifanio, Francesca Faravelli, Debora Formisano, Lucio Giordano, Marina Grasso, Sabine Grønborg, Alessandro Iodice, Lorenzo Iughetti, Didier Lacombe, Massimo Maggi, Baris Malbora, Isabella Mammi, Sebastien Moutton, Rikke Møller, Petra Muschke, Manuela Napoli, Chiara Pantaleoni, Rosario Pascarella, Alessandro Pellicciari, Maria Luisa Poch-Olive, Federico Raviglione, Francesca Rivieri, Carmela Russo, Salvatore Savasta, Gioacchino Scarano, Angelo Selicorni, Margherita Silengo, Giovanni Sorge, Luigi Tarani, Luis Gonzaga Tone, Annick Toutain, Aurelien Trimouille, Elvis Terci Valera, Samantha Schrier Vergano, Nicoletta Zanotta, Marcella Zollino, William B Dobyns, Alex R Paciorkowski
PURPOSE: Mowat-Wilson syndrome (MWS) is a genetic disease characterized by distinctive facial features, moderate to severe intellectual disability, and congenital malformations, including Hirschsprung disease, genital and eye anomalies, and congenital heart defects, caused by haploinsufficiency of the ZEB2 gene. To date, no characteristic pattern of brain dysmorphology in MWS has been defined. METHODS: Through brain magnetic resonance imaging (MRI) analysis, we delineated a neuroimaging phenotype in 54 MWS patients with a proven ZEB2 defect, compared it with the features identified in a thorough review of published cases, and evaluated genotype-phenotype correlations...
November 10, 2016: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/27809679/induction-of-both-local-immune-response-in-mice-and-protection-in-a-rabbit-model-by-intranasal-immunization-with-modified-vaccinia-ankara-virus-expressing-a-secreted-form-of-bovine-herpesvirus-1-glycoprotein-d
#8
María Paula Del Medico Zajac, Flavia Adriana Zanetti, María Soledad Esusy, Carlos Rodolfo Federico, Osvaldo Zabal, Alejandro Rafael Valera, Gabriela Calamante
In this study, we evaluated the immunogenicity and efficacy of mucosal delivery of a recombinant modified vaccinia Ankara virus (MVA) expressing the secreted version of bovine herpesvirus type 1 (BoHV-1) glycoprotein D (MVA-gDs) without addition of adjuvant in two animal models. First, we demonstrated the capability of MVA-gDs of inducing both local and systemic anti-gD humoral immune response after intranasal immunization of mice. Then, we confirmed that two doses of MVA-gDs administered intranasally to rabbits induced systemic anti-gD antibodies and conferred protection against BoHV-1 challenge...
November 3, 2016: Viral Immunology
https://www.readbyqxmd.com/read/27804017/is-it-appropriate-to-treat-sarcoma-metastases-with-intramedullary-nailing
#9
Bryan S Moon, Dwayne J Dunbar, Patrick P Lin, Robert L Satcher, Justin E Bird, Valerae O Lewis
BACKGROUND: Patients with primary bone and soft tissue sarcoma are at risk for skeletal metastases. Although uncommon, these metastases can result in impending or pathologic fractures. Intramedullary nailing traditionally has been an accepted form of palliative treatment for patients with metastatic carcinoma, but we could find no studies that report specifically on intramedullary nailing of metastatic sarcoma lesions. QUESTIONS/PURPOSES: We asked: (1) What is the survival of patients with an impending or pathologic fracture from a sarcoma metastasis? (2) What proportion of patients treated with intramedullary nailing subsequently underwent a revision procedure or nail removal during their lifetimes? METHODS: Between 1996 and 2014, we performed 40 intramedullary nailing procedures in 34 patients with multifocal metastases from sarcomas who showed signs or symptoms of impending fracture or who presented with a pathologic fracture...
November 1, 2016: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/27766587/brain-injury-in-women-experiencing-intimate-partner-violence-neural-mechanistic-evidence-of-an-invisible-trauma
#10
Eve Valera, Aaron Kucyi
Traumatic brain injury (TBI) in women experiencing intimate-partner violence (IPV) is common, and IPV afflicts 30 % of women worldwide. However, the neurobiology and related sequelae of these TBIs have never been systematically examined. Consequently, TBI treatments are typically absent and IPV interventions are inadequate. There has been a call for a comprehensive assessment of IPV-related TBIs and their relationship to aspects of women's cognitive and neural functioning. In response, we examined brain-network organization associated with TBI and its cognitive effects using clinical interviews and neuropsychological measures as well as structural and functional Magnetic Resonance Imaging (fMRI) in women experiencing IPV-related TBI...
October 20, 2016: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/27763446/podcast-interview-transcript
#11
Erin Kobetz, Bruce Armstrong, Pamela Valera
No abstract text is available yet for this article.
2016: Progress in Community Health Partnerships: Research, Education, and Action
https://www.readbyqxmd.com/read/27760132/harmful-effect-of-beer-on-bovine-enamel-microhardness-in-vitro-study
#12
Rayssa Ferreira Zanatta, Maria Ângela Lacerda Rangel Esper, Marcia Carneiro Valera, Renata Marques Melo, Eduardo Bresciani
This study aimed to evaluate the effect of beers on the bovine enamel microhardness. Fifty rectangular (1 x 3 x 1 mm-height x width x thickness) enamel specimens were obtained from permanent bovine incisors, and divided into five groups (n = 10) according to the treatment employed: Saliva, Coke, Brahma, Heineken, and Budweiser. Microhardness (Knoop) were obtained before; after 5, 30 and 60 min of immersion in each solution. The data were analyzed using repeated two-way ANOVA and Tukey´s test (p<0.05). Coke decreased the microhardness in all immersion times, and Heineken, showed low values after 60 minutes...
2016: PloS One
https://www.readbyqxmd.com/read/27746738/the-physiological-mechanisms-of-performance-enhancement-with-sprint-interval-training-differ-between-the-upper-and-lower-extremities-in-humans
#13
Christoph Zinner, David Morales-Alamo, Niels Ørtenblad, Filip J Larsen, Tomas A Schiffer, Sarah J Willis, Miriam Gelabert-Rebato, Mario Perez-Valera, Robert Boushel, Jose A L Calbet, Hans-Christer Holmberg
To elucidate the mechanisms underlying the differences in adaptation of arm and leg muscles to sprint training, over a period of 11 days 16 untrained men performed six sessions of 4-6 × 30-s all-out sprints (SIT) with the legs and arms, separately, with a 1-h interval of recovery. Limb-specific VO2peak, sprint performance (two 30-s Wingate tests with 4-min recovery), muscle efficiency and time-trial performance (TT, 5-min all-out) were assessed and biopsies from the m. vastus lateralis and m. triceps brachii taken before and after training...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27736103/adult-attachment-as-a-moderator-of-the-association-between-childhood-traumatic-experiences-and-depression-symptoms-among-young-black-gay-and-bisexual-men
#14
Stephanie H Cook, Pamela Valera, Benjamin J Calebs, Patrick A Wilson
Objective: The present study examined the moderating effect of adult attachment on the association between childhood traumatic experiences, (i.e., physical abuse, emotional abuse, emotional neglect, and being bullied), age of childhood traumatic experience, and young adult depression symptoms among young Black gay and bisexual men (YBGBM). Method: Self-report measures of attachment, childhood traumatic experiences, and depression symptoms were collected from a community-based sample of YBGBM living in New York City (n = 228)...
October 13, 2016: Cultural Diversity & Ethnic Minority Psychology
https://www.readbyqxmd.com/read/27729152/orofacial-motor-functions-in-pediatric-obstructive-sleep-apnea-and-implications-for-myofunctional-therapy
#15
Cláudia Maria de Felício, Franciele Voltarelli da Silva Dias, Gislaine Aparecida Folha, Leila Azevedo de Almeida, Jaqueline Freitas de Souza, Wilma Terezinha Anselmo-Lima, Luciana Vitaliano Voi Trawitzki, Fabiana Cardoso Pereira Valera
OBJECTIVES: The purposes of this study were (1) to identify possible differences in muscular and orofacial functions between children with obstructive sleep apnea (OSA) and with primary snoring (PS); (2) to examine the standardized difference between normal values of myofunctional scores and those of subjects with OSA or PS; and (3) to identify the features associated with OSA. METHODS: Participants were 39 children (mean age 8 ± 1.2 years) of which, 27 had a diagnosis of OSA and 12 had PS...
November 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27713864/non-radiographic-risk-factors-differentiating-atypical-lipomatous-tumors-from-lipomas
#16
Justin E Bird, Lee Jae Morse, Lei Feng, Wei-Lien Wang, Patrick P Lin, Bryan S Moon, Alexander J Lazar, Robert L Satcher, John E Madewell, Valerae O Lewis
PURPOSE: To determine non-radiographic risk factors differentiating atypical lipomatous tumors (ALTs) from lipomas. METHODS: All patients with deep-seated lipomatous tumors of the extremities treated from January 2000 to October 2010 were retrospectively reviewed. Factors reviewed included age, gender, tumor location, size, histology, local recurrence, dedifferentiation, and metastasis. Multivariate logistic regression models were used to evaluate the effects of patient characteristics on ALT status...
2016: Frontiers in Oncology
https://www.readbyqxmd.com/read/27696711/ewing-sarcoma-family-of-tumors-in-children-younger-than-10-years-of-age
#17
Winston W Huh, Najat C Daw, Cynthia E Herzog, Mark F Munsell, Mary Frances McAleer, Valerae O Lewis
AIM: Few data exist regarding the clinical characteristics and outcome of young children with Ewing sarcoma family of tumors (ESFT). METHODS: We reviewed the records of ESFT patients at our institution younger than 10 years of age at diagnosis. RESULTS: Forty-two patients were identified. Median age was 6.4 years (range 0.6-9.5 years). Most patients had T2 (>5 cm) tumors (n = 31; 74%). Most common primary site was the extremity (n = 17; 41%)...
October 3, 2016: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/27688080/reliability-of-ki-67-determination-in-fna-samples-for-grading-pancreatic-neuroendocrine-tumors
#18
Cristina Díaz Del Arco, J Ángel Díaz Pérez, Luis Ortega Medina, Javier Sastre Valera, M Jesús Fernández Aceñero
Neuroendocrine pancreatic tumors (PanNETs) are graded on the basis of their proliferative activity. Cytological samples are commonly the only samples available, but the determination of Ki-67 in cytology and its reliability as a measure of tumor mitotic activity is not well settled. We have retrospectively reviewed all the cases of FNA under EUS control of PanNETs in a 10-year period (2006-2016) in the Hospital Clínico San Carlos (Madrid). We identified 10 PanNET cases with histological correlation. Median age was 49...
September 29, 2016: Endocrine Pathology
https://www.readbyqxmd.com/read/27669512/is-geo-environmental-exposure-a-risk-factor-for-multiple-sclerosis-a-population-based-cross-sectional-study-in-south-western-sardinia
#19
Maria Cristina Monti, Davide Guido, Cristina Montomoli, Claudia Sardu, Alessandro Sanna, Salvatore Pretti, Lorena Lorefice, Maria Giovanna Marrosu, Paolo Valera, Eleonora Cocco
BACKGROUND: South-Western Sardinia (SWS) is a high risk area for Multiple Sclerosis (MS) with high prevalence and spatial clustering; its population is genetically representative of Sardinians and presents a peculiar environment. We evaluated the MS environmental risk of specific heavy metals (HM) and geographical factors such as solar UV exposure and urbanization by undertaking a population-based cross-sectional study in SWS. METHODS: Geochemical data on HM, UV exposure, urbanization and epidemiological MS data were available for all SWS municipalities...
2016: PloS One
https://www.readbyqxmd.com/read/27644098/qualitative-study-of-the-agitation-states-and-their-characterization-and-the-interventions-used-to-attend-them
#20
María Rubio-Valera, Elena Huerta-Ramos, Luisa Baladón, Ignacio Aznar-Lou, José M Ortiz-Moreno, Juan V Luciano, Pere N Roset-Arisso, Luis Salvador-Carulla, José M Villagrán, Fermín Mayoral, Alfredo Gracia, Antoni Serrano-Blanco
INTRODUCTION: Agitation is a common problem in psychiatric care with serious clinical and economic consequences. METHODOLOGY: The aim of the study was to define and characterize the agitation states present in usual medical practice in the acute and emergency units of a psychiatric hospital. Two nominal groups, one with 7 nurses and the other with 10 psychiatrists from the Parc Sanitari Sant Joan de Déu, were established. RESULTS: The nurses described two main states forming the endpoints of a spectrum: from mild (pre-agitation) to severe (agitation)...
September 2016: Actas Españolas de Psiquiatría
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