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Mirror therapy

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https://www.readbyqxmd.com/read/27909072/the-mirror-illusion-increases-motor-cortex-excitability-in-children-with-and-without-hemiparesis
#1
Sebastian Grunt, Christopher J Newman, Stefanie Saxer, Maja Steinlin, Christian Weisstanner, Alain Kaelin-Lang
Background Mirror therapy provides a visual illusion of a normal moving limb by using the mirror reflection of the unaffected arm instead of viewing the paretic limb and is used in rehabilitation to improve hand function. Little is known about the mechanism underlying its effect in children with hemiparesis. Objective To investigate the effect of the mirror illusion (MI) on the excitability of the primary motor cortex (M1) in children and adolescents. Methods Twelve patients with hemiparesis (10-20 years) and 8 typically developing subjects (8-17 years) participated...
November 30, 2016: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/27886917/coronary-sinus-lead-extraction
#2
REVIEW
Edmond M Cronin, Bruce L Wilkoff
Expanded indications for cardiac resynchronization therapy and the increasing incidence of cardiac implantable electronic device infection have led to an increased need for coronary sinus (CS) lead extraction. The CS presents unique anatomical obstacles to successful lead extraction. Training and facility requirements for CS lead extraction should mirror those for other leads. Here we review the indications, technique, and results of CS lead extraction. Published success rates and complications are similar to those reported for other leads, although multiple techniques may be required...
January 2017: Heart Failure Clinics
https://www.readbyqxmd.com/read/27881113/psychotherapy-integration-under-scrutiny-investigating-the-impact-of-integrating-emotion-focused-components-into-a-cbt-based-approach-a-study-protocol-of-a-randomized-controlled-trial
#3
Anna Babl, Martin Grosse Holtforth, Sara Heer, Mu Lin, Annabarbara Stähli, Dominique Holstein, Martina Belz, Yvonne Egenolf, Eveline Frischknecht, Fabian Ramseyer, Daniel Regli, Emma Schmied, Christoph Flückiger, Jeannette Brodbeck, Thomas Berger, Franz Caspar
BACKGROUND: This currently recruiting randomized controlled trial investigates the effects of integrating components of Emotion-Focused Therapy (EFT) into Psychological Therapy (PT), an integrative form of cognitive-behavioral therapy in a manner that is directly mirroring common integrative practice in the sense of assimilative integration. Aims of the study are to understand how both, an existing therapy approach as well as the elements to be integrated, are affected by the integration and to clarify the role of emotional processing as a mediator of therapy outcome...
November 24, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27858687/update-on-the-effects-of-graded-motor-imagery-and-mirror-therapy-on-complex-regional-pain-syndrome-type-1-a-systematic-review
#4
Guillermo Méndez-Rebolledo, Valeska Gatica-Rojas, Rafael Torres-Cueco, María Albornoz-Verdugo, Eduardo Guzmán-Muñoz
Graded motor imagery (GMI) and mirror therapy (MT) is thought to improve pain in patients with complex regional pain syndrome (CRPS) types 1 and 2. However, the evidence is limited and analysis are not independent between types of CRPS. The purpose of this review was to analyze the effects of GMI and MT on pain in independent groups of patients with CRPS types 1 and 2. Searches for literature published between 1990 and 2016 were conducted in databases. Randomized controlled trials that compared GMI or MT with other treatments for CRPS types 1 and 2 were included...
November 11, 2016: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/27827332/a-preventative-respiratory-protocol-to-identify-trauma-subjects-at-risk-for-respiratory-compromise-on-a-general-in-patient-ward
#5
Bethany A Nyland, Sarah K Spilman, Meghan E Halub, Keith D Lamb, Julie A Jackson, Trevor W Oetting, Sheryl M Sahr
BACKGROUND: Patients are at risk for respiratory complications after sustaining blunt chest trauma, yet contradictory evidence exists about the utility of prophylactic respiratory therapy to reduce respiratory complications in this population. This study assessed the effectiveness of a proactive respiratory protocol on an in-patient ward to identify trauma patients at risk for pulmonary complications, administer appropriate therapies, and prevent deterioration requiring transfer to the ICU...
December 2016: Respiratory Care
https://www.readbyqxmd.com/read/27826529/exosomes-genetic-cargo-in-lung-cancer-a-truly-pandora-s-box
#6
REVIEW
Pablo Reclusa, Rafael Sirera, Antonio Araujo, Marco Giallombardo, Anna Valentino, Laure Sorber, Ignacio Gil Bazo, Patrick Pauwels, Christian Rolfo
Lung cancer is a highly lethal disease. Targeted therapies have been developed in last years, however survival rates are not improving due to the delay in the diagnosis, making biomarkers one of the most interesting fields of study in cancer. Liquid biopsy has raised as an alternative to tissue biopsy due to improvements in analytical techniques for circulating tumor cells (CTCs), cell free DNA and exosomes. Among all, exosomes have raised as one of the most promising tools to understand the tumor due to their stability in the blood and their similarity to the cells of origin...
October 2016: Translational Lung Cancer Research
https://www.readbyqxmd.com/read/27818734/coconut-oil-extract-mitigates-testicular-injury-following-adjuvant-treatment-with-antiretroviral-drugs
#7
Oluwatosin O Ogedengbe, Ayoola I Jegede, Ismail O Onanuga, Ugochukwu Offor, Edwin Cs Naidu, Aniekan I Peter, Onyemaechi O Azu
Increased access to highly active antiretroviral therapy (HAART) has made the management of drug toxicities an increasingly crucial component of HIV. This study investigated the effects of adjuvant use of coconut oil and HAART on testicular morphology and seminal parameters in Sprague- Dawley rats. Twelve adult male Sprague-Dawley rats, weighing 153~169 g were distributed into four groups (A-D) and treated as follows: A served as control (distilled water); B (HAART cocktail- Zidovudine, Lamivudine and Nevirapine); C (HAART + Virgin coconut oil 10 mL/kg) and D (Virgin coconut oil 10 mL/kg)...
October 2016: Toxicological Research
https://www.readbyqxmd.com/read/27813030/the-effect-of-mirror-therapy-on-the-management-of-phantom-limb-pain
#8
Meltem Yıldırım, Nevin Kanan
OBJECTIVES: In the last two decades, mirror therapy has become a frequently used method of managing phantom limb pain (PLP). However, the role of nurses in mirror therapy has not yet been well defined. This study examined the effect of mirror therapy on the management of PLP, and discusses the importance of mirror therapy in the nursing care of amputee patients. METHODS: This quasi-experimental study was conducted in the pain management department of a university hospital and a prosthesis clinic in İstanbul, Turkey, with 15 amputee patients who had PLP...
July 2016: Aǧrı: Ağrı (Algoloji) Derneği'nin Yayın Organıdır, the Journal of the Turkish Society of Algology
https://www.readbyqxmd.com/read/27804036/association-between-familial-hypobetalipoproteinemia-and-the-risk-of-diabetes-is-this-the-other-side-of-the-cholesterol-diabetes-connection-a-systematic-review-of-literature
#9
REVIEW
Davide Noto, Marcello Arca, Patrizia Tarugi, Angelo B Cefalù, Carlo M Barbagallo, Maurizio R Averna
Statin therapy is beneficial in reducing LDL cholesterol (LDL-C) levels and cardiovascular events, but it is associated with the risk of incident diabetes mellitus (DM). Familial hypercholesterolemia (FH) is characterized by genetically determined high levels of plasma LDL-C and a low prevalence of DM. LDL-C levels seem then inversely correlated with prevalence of DM. Familial hypobetalipoproteinemia (FHBL) represents the genetic mirror of FH in terms of LDL-C levels, very low in subjects carrying mutations of APOB, PCSK9 (FHBL1) or ANGPTL3 (FHBL2)...
November 2, 2016: Acta Diabetologica
https://www.readbyqxmd.com/read/27799679/effect-of-mirror-therapy-on-upper-extremity-motor-function-in-stroke-patients-a-randomized-controlled-trial
#10
Nigar Gurbuz, Sevgi Ikbali Afsar, Sehri Ayaş, Sacide Nur Saracgil Cosar
[Purpose] This study aimed to evaluate the effectiveness of mirror therapy combined with a conventional rehabilitation program on upper extremity motor and functional recovery in stroke patients. [Subjects and Methods] Thirty-one hemiplegic patients were included. The patients were randomly assigned to a mirror (n=16) or conventional group (n=15). The patients in both groups underwent conventional therapy for 4 weeks (60-120 minutes/day, 5 days/week). The mirror group received mirror therapy, consisting of periodic flexion and extension movements of the wrist and fingers on the non-paralyzed side...
September 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/27794406/the-impact-of-lung-cancer-surgery-on-quality-of-life-trajectories-in-patients-and-family-caregivers
#11
Jae Y Kim, Virginia Sun, Dan J Raz, Anna Cathy Williams, Rebecca Fujinami, Karen Reckamp, Marianna Koczywas, Mihaela Cristea, Arti Hurria, Betty Ferrell
OBJECTIVES: Family caregivers (FCGs) play an important role in the quality of life (QOL) of lung cancer patients. FCGs experience significant psychological distress related to their caregiving role, but there is relatively little data about FCG QOL after cancer surgery. We sought to describe QOL trajectories for patients and their FCGs after lung cancer surgery. METHODS: This is a secondary analysis of a larger, prospective QOL study, testing the effectiveness of an interdisciplinary palliative care intervention for lung cancer patients and FCGs in a single institution...
November 2016: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/27791207/virtual-reality-reflection-therapy-improves-balance-and-gait-in-patients-with-chronic-stroke-randomized-controlled-trials
#12
Taesung In, Kyeongjin Lee, Changho Song
BACKGROUND Virtual reality reflection therapy (VRRT) is a technically enhanced version of the mirror therapy concept. The aim of this study was to investigate whether VRRT could improve the postural balance and gait ability of patients with chronic stroke. MATERIAL AND METHODS Twenty-five patients with chronic stroke were randomly allocated into the VRRT group (n=13) and the control group (n=12). The participants in both groups performed a conventional rehabilitation program for 30 minutes. The VRRT group also performed a VRRT program for 30 minutes, five times a week for 4 weeks...
October 28, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27782712/use-of-regularized-principal-component-analysis-to-model-anatomical-changes-during-head-and-neck-radiation-therapy-for-treatment-adaptation-and-response-assessment
#13
Mikhail A Chetvertkov, Farzan Siddiqui, Jinkoo Kim, Indrin Chetty, Akila Kumarasiri, Chang Liu, J James Gordon
PURPOSE: To develop standard (SPCA) and regularized (RPCA) principal component analysis models of anatomical changes from daily cone beam CTs (CBCTs) of head and neck (H&N) patients and assess their potential use in adaptive radiation therapy, and for extracting quantitative information for treatment response assessment. METHODS: Planning CT images of ten H&N patients were artificially deformed to create "digital phantom" images, which modeled systematic anatomical changes during radiation therapy...
October 2016: Medical Physics
https://www.readbyqxmd.com/read/27778161/brain-plasticity-in-parkinson-s-disease-with-freezing-of-gait-induced-by-action-observation-training
#14
Federica Agosta, Roberto Gatti, Elisabetta Sarasso, Maria Antonietta Volonté, Elisa Canu, Alessandro Meani, Lidia Sarro, Massimiliano Copetti, Erik Cattrysse, Eric Kerckhofs, Giancarlo Comi, Andrea Falini, Massimo Filippi
Gait disorders represent a therapeutic challenge in Parkinson's disease (PD). This study investigated the efficacy of 4-week action observation training (AOT) on disease severity, freezing of gait and motor abilities in PD, and evaluated treatment-related brain functional changes. 25 PD patients with freezing of gait were randomized into two groups: AOT (action observation combined with practicing the observed actions) and "Landscape" (same physical training combined with landscape-videos observation). At baseline and 4-week, patients underwent clinical evaluation and fMRI...
October 24, 2016: Journal of Neurology
https://www.readbyqxmd.com/read/27776125/immunotherapeutic-potential-of-eugenol-emulsion-in-experimental-visceral-leishmaniasis
#15
Mohammad Islamuddin, Garima Chouhan, Muzamil Yaqub Want, Hani A Ozbak, Hassan A Hemeg, Farhat Afrin
BACKGROUND: The therapy of visceral leishmaniasis (VL) is limited by resistance, toxicity and decreased bioavailability of the existing drugs coupled with dramatic increase in HIV-co-infection, non-availability of vaccines and down regulation of cell-mediated immunity (CMI). Thus, we envisaged combating the problem with plant-derived antileishmanial drug that could concomitantly mitigate the immune suppression of the infected hosts. Several plant-derived compounds have been found to exert leishmanicidal activity via immunomodulation...
October 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27756693/it-s-all-in-the-type-of-the-task-dopamine-modulates-kinematic-patterns-during-competitive-vs-cooperative-interaction-in-parkinson-s-disease
#16
Elisa Straulino, Tomaso Scaravilli, Maria Bulgheroni, Enrico D'Amico, Umberto Castiello
Increasing evidence suggests that a dysfunctional dopaminergic system affects the ability to socially interact. Since Parkinson's disease (PD) provides a model for assessing dopaminergic dysfunctions in humans, our study was designed to investigate social interactions in PD patients receiving dopamine replacement therapy (Levodopa=l-Dopa) and in neurologically healthy controls. We focused on the kinematics of one action, reaching to grasp a wooden block, which was performed within the context of two basic modes of social cognition, namely cooperation and competition...
October 15, 2016: Neuropsychologia
https://www.readbyqxmd.com/read/27754721/evidence-based-endothelial-rehabilitation
#17
Shaohui Liu, Peter Veldman
Endothelial keratoplasty (EK) has replaced penetrating keratoplasty (PKP) as the preferred surgical therapy for corneal endothelial dysfunction. However, recent nationwide corneal graft registry data showed few advantages to EK relative to PKP with respect to graft survival and visual outcomes. This article compares the published outcomes and complications of EK to those of PKP. EK demonstrates superior spectacle corrected visual outcomes, fast recovery, less graft rejection, and higher patient satisfaction, particularly in studies performed by high-volume surgeons/centers...
October 18, 2016: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/27752089/apigenin-potentiates-trail-therapy-of-non-small-cell-lung-cancer-via-upregulating-dr4-dr5-expression-in-a-p53-dependent-manner
#18
Minghui Chen, Xueshi Wang, Daolong Zha, Fangfang Cai, Wenjing Zhang, Yan He, Qilai Huang, Hongqin Zhuang, Zi-Chun Hua
Apigenin (APG) is an edible plant-derived flavonoid that shows modest antitumor activities in vitro and in vivo. APG treatment results in cell growth arrest and apoptosis in various types of tumors by modulating several signaling pathways. In the present study, we evaluated interactions between APG and TRAIL in non-small cell lung cancer (NSCLC) cells. We observed a synergistic effect between APG and TRAIL on apoptosis of NSCLC cells. A549 cells and H1299 cells were resistant to TRAIL treatment alone. The presence of APG sensitized NSCLC cells to TRAIL-induced apoptosis by upregulating the levels of death receptor 4 (DR4) and death receptor 5 (DR5) in a p53-dependent manner...
October 18, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27746051/metformin-targets-central-carbon-metabolism-and-reveals-mitochondrial-requirements-in-human-cancers
#19
Xiaojing Liu, Iris L Romero, Lacey M Litchfield, Ernst Lengyel, Jason W Locasale
Repurposing metformin for cancer therapy is attractive due to its safety profile, epidemiological evidence, and encouraging data from human clinical trials. Although it is known to systemically affect glucose metabolism in liver, muscle, gut, and other tissues, the molecular determinants that predict a patient response in cancer remain unknown. Here, we carry out an integrative metabolomics analysis of metformin action in ovarian cancer. Metformin accumulated in patient biopsies, and pathways involving nucleotide metabolism, redox, and energy status, all related to mitochondrial metabolism, were affected in treated tumors...
October 12, 2016: Cell Metabolism
https://www.readbyqxmd.com/read/27744486/changes-in-chemotherapy-usage-and-outcome-of-early-breast-cancer-patients-in-the-last-decade
#20
A Hennigs, F Riedel, F Marmé, P Sinn, K Lindel, A Gondos, K Smetanay, M Golatta, C Sohn, F Schuetz, J Heil, A Schneeweiss
BACKGROUND: During the last decade, neoadjuvant chemotherapy (NACT) of early breast cancer (EBC) evolved from a therapy intended to enable operability to a standard treatment option aiming for increasing cure rates equivalent to adjuvant chemotherapy (ACT). In parallel, improvements in the quality control of breast cancer care have been established in specialized breast care units. PATIENTS AND METHODS: This study analyzed chemotherapy usage in patients with EBC treated at the Heidelberg University Breast Unit between January 2003 and December 2014...
December 2016: Breast Cancer Research and Treatment
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