keyword
https://read.qxmd.com/read/31114312/comparison-of-subcutaneous-dexmedetomidine-versus-clonidine-as-an-adjuvant-to-spinal-anesthesia-a-randomized-double-blind-control-trial
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JOURNAL ARTICLE
Divya B Srinivas, Geetha Lakshminarasimhaiah
Background: Alpha-2 adrenergic agonists like clonidine and dexmedetomidine prolong the duration of postoperative analgesia and improve the quality of subarachnoid block (SAB) when used as adjuvant in various routes. However, addition of these drugs by IV or intrathecal routes are known to cause hemodynamic instability. The subcutaneous (SC) route provides similar efficacy as IV administration with less hemodynamic instability and prolonged effect. Aims : To compare the efficacy of clonidine and dexmedetomidine as adjuvants to SAB when used subcutaneously...
2019: Local and Regional Anesthesia
https://read.qxmd.com/read/26894153/comparison-of-epidural-bupivacaine-levobupivacaine-and-dexmedetomidine-in-patients-undergoing-vascular-surgery
#2
JOURNAL ARTICLE
Lakshmi Adalagere Sathyanarayana, Vijayakumar M Heggeri, Parimala Prasanna Simha, Satish Narasimaiah, Manjunath Narasimaiah, Bharathi Katheraguppa Subbarao
INTRODUCTION: Levobupivacaine is the s-isomer of racemic Bupivacaine. It is less cardio, neurotoxic and equally potent local anaesthetic compared to its racemate. It is known to cause less Depression of myocardial contractility. Dexmeditomidine when used via epidural route has synergistic effect with local anaesthetics. Majority of patients presenting for vascular surgery are elderly and have associated co-morbidities like diabetes, hypertension, and coronary artery disease. We intend to study safety and efficacy of epidural Levoupivacaine and Dexmedetomidine in this group of patients...
January 2016: Journal of Clinical and Diagnostic Research: JCDR
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