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https://www.readbyqxmd.com/read/28086971/characteristics-and-use-of-urban-health-indicator-tools-by-municipal-built-environment-policy-and-decision-makers-a-systematic-review-protocol
#1
Helen Pineo, Ketevan Glonti, Harry Rutter, Nicole Zimmermann, Paul Wilkinson, Michael Davies
BACKGROUND: There is wide agreement that there is a lack of attention to health in municipal environmental policy-making, such as urban planning and regeneration. Explanations for this include differing professional norms between health and urban environment professionals, system complexity and limited evidence for causality between attributes of the built environment and health outcomes. Data from urban health indicator (UHI) tools are potentially a valuable form of evidence for local government policy and decision-makers...
January 13, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28081513/thrombosis-of-a-mechanical-prosthetic-aortic-valve-in-early-pregnancy-histopathological-findings
#2
Roman Scheidmann, Rudi Foth, Matthias Sigler
We present results of the histopathological workup of a prosthetic aortic valve which was explanted from a 31-year-old woman due to valve thrombosis during early pregnancy. Our images demonstrate nicely thrombotic material directly adherent to the pyrolytic carbon surface in a human specimen.
January 2, 2017: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/28077655/expression-of-ifnlr1-on-intestinal-epithelial-cells-is-critical-to-the-antiviral-effects-of-ifn-lambda-against-norovirus-and-reovirus
#3
Megan T Baldridge, Sanghyun Lee, Judy J Brown, Nicole McAllister, Kelly Urbanek, Terence S Dermody, Timothy J Nice, Herbert W Virgin
: Interferon-lambda (IFN-λ) has potent antiviral effects against multiple enteric viral pathogens, including norovirus and rotavirus, in both preventing and curing infection. Because the intestine includes a diverse array of cell types, however, the cell(s) upon which IFN-λ acts to exert its antiviral effects are unclear. Here, we sought to identify IFN-λ responsive cells by generation of mice with lineage-specific deletion of the receptor for IFN-λ, Ifnlr1 We found that expression of IFNLR1 on intestinal epithelial cells (IECs) in the small intestine and colon is required for enteric IFN-λ antiviral activity...
January 11, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28076982/from-structure-to-activity-using-centrality-measures-to-predict-neuronal-activity
#4
Jack McKay Fletcher, Thomas Wennekers
It is clear that the topological structure of a neural network somehow determines the activity of the neurons within it. In the present work, we ask to what extent it is possible to examine the structural features of a network and learn something about its activity? Specifically, we consider how the centrality (the importance of a node in a network) of a neuron correlates with its firing rate. To investigate, we apply an array of centrality measures, including In-Degree, Closeness, Betweenness, Eigenvector, Katz, PageRank, Hyperlink-Induced Topic Search (HITS) and NeuronRank to Leaky-Integrate and Fire neural networks with different connectivity schemes...
November 16, 2016: International Journal of Neural Systems
https://www.readbyqxmd.com/read/28075297/physical-health-of-people-in-prison
#5
Lynne Pearce
Essential facts Since 2013, NHS England has commissioned health services for prisoners in England. The National Institute for Health and Care Excellence (NICE) says health care in prison plays an important role in identifying health needs, including chronic conditions.
January 11, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28074641/editorial-methods-and-advances-for-systems-and-synthetic-biology-nanobiotech-and-medicine
#6
EDITORIAL
Jing Zhu, Uta Goebel
Congratulations to the winners of our cover competition. The first prize goes to the cover of the October issue, which was provided by the authors of the article "Chlorella species as hosts for genetic engineering and expression of heterologous proteins: Progress, challenge and perspective" by Bo Yang, Jin Liu, Yue Jiang and Feng Chen (http://dx.doi.org/10.1002/biot.201500617). Very close by only very few votes followed the July issue cover showing a nice illustration of Aspergillus fungi, which was selected by BTJs Production manager Sigi Mehren and Technical editor Bernadette Gmeiner...
January 2017: Biotechnology Journal
https://www.readbyqxmd.com/read/28073104/use-of-transcutaneous-bilirubin-to-determine-the-need-for-phototherapy-in-resource-limited-settings
#7
Bolajoko O Olusanya, Abieyuwa A Emokpae
BACKGROUND: Routine and timely determination of total serum bilirubin (TSB) remains a challenge in many resource-limited countries with substantial burden of severe neonatal hyperbilirubinemia. Limited evidence exists on the potential usefulness of transcutaneous bilirubin (TcB) to identify infants who may require phototherapy based on possible treatment criteria in such settings. OBJECTIVE: To compare the number of infants requiring phototherapy across different TSB criteria and determine the predictive performance of TcB under each criterion...
January 11, 2017: Neonatology
https://www.readbyqxmd.com/read/28062522/low-back-pain-and-sciatica-summary-of-nice-guidance
#8
Ian A Bernstein, Qudsia Malik, Serena Carville, Stephen Ward
No abstract text is available yet for this article.
January 6, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28058776/guideline-of-guidelines-non-muscle-invasive-bladder-cancer
#9
REVIEW
Solomon L Woldu, Aditya Bagrodia, Yair Lotan
Non-muscle invasive bladder cancer (NMIBC) represents the vast majority of bladder cancer diagnoses, however this definition represents a spectrum of disease with a variable clinical course notable for significant risk of recurrence and potential for progression. Management involves risk-adapted strategies of cystoscopic surveillance and intravesical therapy with a goal of bladder preservation when safe to do so. Multiple organizational guidelines exist to help practitioners manage this complicated disease process, however adherence to management principles amongt practicing urologists is reportedly low...
January 6, 2017: BJU International
https://www.readbyqxmd.com/read/28056656/age-and-pubertal-status-related-changes-in-reports-of-perception-of-personal-odors
#10
Lenka Martinec Nováková, Dagmar Plotěná, Jan Havlíček
As previously suggested, preferences for kin body odor might undergo an adaptive change over the course of puberty in order to avoid potential inbreeding, resulting in aversion to body odor of the opposite-gender kin as individuals mature sexually. However, studies based on mutual body odor aversion are rather inconclusive. We therefore investigated whether children's reports of individuals smelling good or bad differed as a function of age and pubertal status. We asked 219 children (94 male) aged 10 to 15 years to assess their pubertal development using a standardized measure and to name individuals they thought smelled good or bad...
January 1, 2017: Perception
https://www.readbyqxmd.com/read/28055924/robust-c-loss-kernel-classifiers
#11
Guibiao Xu, Bao-Gang Hu, Jose C Principe
The correntropy-induced loss (C-loss) function has the nice property of being robust to outliers. In this paper, we study the C-loss kernel classifier with the Tikhonov regularization term, which is used to avoid overfitting. After using the half-quadratic optimization algorithm, which converges much faster than the gradient optimization algorithm, we find out that the resulting C-loss kernel classifier is equivalent to an iterative weighted least square support vector machine (LS-SVM). This relationship helps explain the robustness of iterative weighted LS-SVM from the correntropy and density estimation perspectives...
December 29, 2016: IEEE Transactions on Neural Networks and Learning Systems
https://www.readbyqxmd.com/read/28054831/lessons-learned-from-an-unstable-genomic-landscape
#12
Charles L Limoli
PURPOSE: This brief historical perspective will highlight the many accomplishments of the late William "Bill" Morgan, and how his laboratory during the mid-1990s shaped the field of genomic instability. Bill focused on the processes responsible for radiation-induced genomic instability, and while ionizing radiation was known to induce this phenomenon, the precise causes were poorly understood. Here we revisit Bill's unique approach to these problems, as he advocated the use of novel mammalian cell lines to tease apart the mechanisms responsible for destabilizing an otherwise stable nuclear genome...
January 5, 2017: International Journal of Radiation Biology
https://www.readbyqxmd.com/read/28045154/mechanism-of-coverage-dependent-co-adsorption-and-dissociation-on-the-mo-100-surface
#13
Xinxin Tian, Tao Wang, Haijun Jiao
The mechanism of coverage dependent CO adsorption and dissociation on the Mo(100) surface was investigated using periodic density functional theory. Structure optimization and frequency calculation were carried out using the GGA-PBE method and a p(3 × 3) supercell model. Energetic data have been obtained using the revised PBE method and the PBE optimized structures. CO adsorption prefers tilted adsorption configuration at the 4-fold hollow sites at low coverage and tilted and atop configurations at high coverage...
January 3, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28044348/early-recognition-and-detection-of-juvenile-psoriatic-arthritis-a-call-for-a-standardized-approach-to-screening
#14
E Burden-Teh, K S Thomas, S Rangaraj, J Cranwell, R Murphy
BACKGROUND: National Institute for Health and Care Excellence (NICE) guidelines recommend annual screening for psoriatic arthritis (PsA) in all patients with psoriasis. Currently, no validated assessment tools have been recommended for screening for juvenile PsA (JPsA). AIM: To determine dermatologists' practice when assessing children's joints and explore the challenges dermatologists experience when looking for joint disease, in order to inform future strategies to improve early detection of arthritis...
January 2, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28042963/a-systematic-review-of-brief-mental-health-and-well-being-interventions-in-organizational-settings
#15
Ivana Ivandic, Aislinne Freeman, Ulrich Birner, Dennis Nowak, Carla Sabariego
Objectives The aim of the systematic review was to provide an overview of the evidence on the effectiveness of brief interventions targeting mental health and well-being in organizational settings and compare their effects with corresponding interventions of common (ie, longer) duration. Methods An extensive systematic search was conducted using the Medline and PsycINFO databases for the period of 2000-2016. Randomized-controlled trials (RCT) and quasi-experimental studies evaluating primary or secondary brief interventions carried out in the workplace settings were included...
January 2, 2017: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/28040304/validation-of-igg-igm-multiplex-plasmonic-gold-platform-in-french-clinical-cohorts-for-the-serodiagnosis-and-follow-up-of-toxoplasma-gondii-infection
#16
Christelle Pomares, Bo Zhang, Shylaja Arulkumar, Geraldine Gonfrier, Pierre Marty, Su Zhao, Steven Cheng, Meijie Tang, Hongjie Dai, Jose G Montoya
We report the use of the multiplexed T. gondii IgG, IgM test on plasmonic gold (pGOLD) platform in the setting of T. gondii infection by analyzing 244 sera from Nice, France (seroconversion, chronically infected, non-infected and newborns serum samples). Results were compared with commercial tests for the detection of IgG and IgM and their overall clinical final interpretation of a complete serological profile. The IgG and IgM test results on the platform were in agreement in, respectively, 95% and 93% with the commercial kits...
September 8, 2016: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/28039637/design-synthesis-in-silico-and-biological-evaluation-of-novel-2-4-4-substituted-piperazin-1-yl-benzylidene-hydrazine-carboxamides
#17
Shikha Kumari, Chandra Bhushan Mishra, Danish Idrees, Amresh Prakash, Rajesh Yadav, Md Imtaiyaz Hassan, Manisha Tiwari
A series of novel 2-(4-(4-substituted piperazin-1-yl)benzylidene)hydrazinecarboxamide derivatives has been successfully designed and synthesized to evaluate their potential as carbonic anhydrase (CA) inhibitors. The inhibitory potential of synthesized compounds against human CAI and CAII was evaluated. Compounds 3a-n exhibited [Formula: see text] values between [Formula: see text] against CAI and [Formula: see text] against CAII. Compound 3g was the most active inhibitor, with an [Formula: see text] value of [Formula: see text] against CAII...
December 30, 2016: Molecular Diversity
https://www.readbyqxmd.com/read/28039196/nice-public-health-guidance-healthy-workplaces
#18
REVIEW
Eileen Taylor, Caroline Mulvihill, Nick Baillie, Holly Irwin
No abstract text is available yet for this article.
December 29, 2016: Journal of Public Health
https://www.readbyqxmd.com/read/28035800/in-situ-generation-of-pd-pt-core-shell-nanoparticles-on-reduced-graphene-oxide-pd-pt-rgo-using-microwaves-applications-in-dehalogenation-reactions-and-reduction-of-olefins
#19
Anandarup Goswami, Anuj K Rathi, Claudia Aparicio, Ondrej Tomanec, Martin Petr, Radka Pocklanova, Manoj B Gawande, Rajender S Varma, Radek Zboril
Core-shell nanocatalysts are a distinctive class of nanomaterials with varied potential applications in view of their unique structure, composition-dependent physicochemical properties, and promising synergism among the individual components. A one-pot microwave (MW)-assisted approach is described to prepare the reduced graphene oxide (rGO)-supported Pd-Pt core-shell nanoparticles, (Pd@Pt/rGO); spherical core-shell nanomaterials (∼95 nm) with Pd core (∼80 nm) and 15 nm Pt shell were nicely distributed on the rGO matrix in view of the choice of reductant and reaction conditions...
January 11, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28032876/evaluaci%C3%A3-n-de-las-evidencias-y-calidad-de-las-gu%C3%A3-as-de-pr%C3%A3-ctica-cl%C3%A3-nica-sobre-deterioro-de-la-integridad-cut%C3%A3-nea-%C3%A3%C2%BAlceras-y-heridas-cr%C3%A3-nicas
#20
J M Rumbo Prieto, M Romero Martín, D Bellido Guerrero, L Arantón Areosa, C D Raña Lama, F Palomar Llatas
Fundamento. La situación epidemiológica, sociosanitaria y económica que rodea al deterioro de la integridad cutánea supone un gran problema para el sistema sanitario. Su prevención y tratamiento crea incertidumbre y variabilidad profesional siendo prioritario contar con buenas Guías de Práctica Clínica (GPC). El objetivo fue conocer la calidad de las GPC sobre prevención y tratamiento de úlceras por presión (UPP), úlceras venosas de la pierna (UVP) y úlceras de pie diabético (UPD). Metodología...
December 30, 2016: Anales del Sistema Sanitario de Navarra
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