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https://www.readbyqxmd.com/read/29475210/-comparison-of-international-guidelines-for-the-application-of-cardiotocography
#1
Phillip Schulten Sebastian, Jan Philip Suppelna, Timoleon Dagres, Günter Noè, Michael Anapolski, Joscha Reinhard, Harald Krentel, Clemens Tempfer, Sven Schiermeier
OBJECTIVE: This study examines the recommendations of international guidelines on the use of antepartum and intrapartum cardiotocography. MATERIAL AND METHODS: The guidelines of Germany, Canada, UK, USA, Sri Lanka, Australia as well as FIGO have been compared. The recommendations on the use of cardiotocography were separately evaluated for antepartum and intrapartum use. RESULTS: Antepartum: In risk-free pregnancies the use of cardiotocography is not recommended in all countries...
February 23, 2018: Zeitschrift Für Geburtshilfe und Neonatologie
https://www.readbyqxmd.com/read/29471982/decreasing-caregivers-positive-attitudes-toward-spanking
#2
Kimberly Burkhart, Michele Knox, Kimberly Hunter, Deanna Pennewitt, Karyssa Schrouder
The Play Nicely program is a multimedia training program designed to teach caregivers and health care professionals how to manage early childhood aggression and to use positive parenting practices. The aim of this article is to help the practicing clinician determine whether the Play Nicely program should be incorporated into his/her practice and to evaluate whether the program is effective at decreasing positive attitudes toward spanking in a socioeconomically disadvantaged population in both a resident pediatric clinic and a community center...
February 19, 2018: Journal of Pediatric Health Care
https://www.readbyqxmd.com/read/29471861/investigating-the-effectiveness-and-cost-effectiveness-of-fitnet-nhs-fatigue-in-teenagers-on-the-internet-in-the-nhs-compared-to-activity-management-to-treat-paediatric-chronic-fatigue-syndrome-cfs-myalgic-encephalomyelitis-me-protocol-for-a-randomised-controlled
#3
Sarah Baos, Amberly Brigden, Emma Anderson, William Hollingworth, Simon Price, Nicola Mills, Lucy Beasant, Daisy Gaunt, Kirsty Garfield, Chris Metcalfe, Roxanne Parslow, Harriet Downing, David Kessler, John Macleod, Paul Stallard, Hans Knoop, Elise Van de Putte, Sanne Nijhof, Gijs Bleijenberg, Esther Crawley
BACKGROUND: Paediatric chronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME) is a relatively common and disabling condition. The National Institute for Health and Clinical Excellence (NICE) recommends Cognitive Behavioural Therapy (CBT) as a treatment option for paediatric CFS/ME because there is good evidence that it is effective. Despite this, most young people in the UK are unable to access local specialist CBT for CFS/ME. A randomised controlled trial (RCT) showed FITNET was effective in the Netherlands but we do not know if it is effective in the National Health Service (NHS) or if it is cost-effective...
February 22, 2018: Trials
https://www.readbyqxmd.com/read/29470277/does-duration-of-pain-at-baseline-influence-clinical-outcomes-of-low-back-pain-patients-managed-on-an-evidence-based-pathway
#4
Mary-Anne Jess, Ryan Cormac, Sharon Hamilton, Shaun Wellburn, Greg Atkinson, Charles Greenough, Andrew Coxon, Diarmaid Ferguson, Francis Fatoye, John Dickson, Andrea Jones, Denis Martin
Supplemental Digital Content is available in the text STUDY DESIGN.: Longitudinal observational study. OBJECTIVE: To investigate the association between the duration of pain at baseline and the clinical outcomes of patients with low back pain (LBP) enrolled on the North East of England Regional Back Pain and Radicular Pain Pathway (NERBPP). SUMMARY OF BACKGROUND DATA: The NERBPP is a clinical pathway based upon NICE guidelines (2009) for LBP of <1-year duration...
February 21, 2018: Spine
https://www.readbyqxmd.com/read/29467134/nhs-diabetes-prevention-programme-in-england-formative-evaluation-of-the-programme-in-early-phase-implementation
#5
Linda Penn, Angela Rodrigues, Anna Haste, Marta M Marques, Kirsten Budig, Kirby Sainsbury, Ruth Bell, Vera Araújo-Soares, Martin White, Carolyn Summerbell, Elizabeth Goyder, Alan Brennan, Ashley J Adamson, Falko F Sniehotta
OBJECTIVES: Evaluation of the demonstrator phase and first wave roll-out of the National Health Service (NHS) Diabetes Prevention Programme (DPP) in England. To examine: (1) intervention design, provision and fidelity assessment procedures; (2) risk assessment and recruitment pathways and (3) data collection for monitoring and evaluation. To provide recommendations informing decision makers on programme quality, improvements and future evaluation. DESIGN: We reviewed programme documents, mapping against the NHS DPP specification and National Institute for Health and Care Excellence (NICE) public health guideline: Type 2 diabetes (T2D) prevention in people at high risk (PH38), conducted qualitative research using individual interviews and focus group discussions with stakeholders and examined recruitment, fidelity and data collection procedures...
February 21, 2018: BMJ Open
https://www.readbyqxmd.com/read/29463046/a-novel-hard-decision-based-simultaneous-target-tracking-and-classification-approach
#6
Wen Cao, Meng Hui, Qisheng Wu
Methods dealing with the problem of Joint Tracking and Classification (JTC) are abundant, among which Simultaneous Tracking and Classification (STC) provides a modularized scheme solving tracking and classification subproblems simultaneously. However, there is no explicit hard decision on the class label but only soft decision (class probability) is provided. This does not fit many practical cases, in which a hard decision is urgently needed. To solve this problem, this paper proposes a Hard decision-based STC (HSTC) method...
February 19, 2018: Sensors
https://www.readbyqxmd.com/read/29462585/social-behavior-bonobos-are-nice-but-prefer-mean-guys
#7
J Kiley Hamlin
Human infants prefer to interact with prosocial individuals. Bonobos, our close relatives, however, prefer antisocial individuals, perhaps due to a preference for social dominance. Human prosocial behavior may be due to unique tendencies to positively evaluate prosocial others.
February 19, 2018: Current Biology: CB
https://www.readbyqxmd.com/read/29462357/nice-public-health-guidance-update
#8
Kay Nolan, Peter Shearn, Maryam Gholitabar, Judith Richardson
No abstract text is available yet for this article.
February 16, 2018: Journal of Public Health
https://www.readbyqxmd.com/read/29461932/clinical-outcomes-from-a-10-week-follow-up-psychoeducational-programme-for-dual-diagnosis
#9
J Chilton, D Crone, P J Tyson
BACKGROUND: Dual diagnosis covers a broad spectrum of mental health and substance misuse conditions occurring concurrently (NICE, 2016). Its manifestation is complex and as such, the disorder is recognized as influencing adherence to prescribed medication, service engagement and has a worse prognosis than substance use and mental health conditions occurring independently. AIMS: To determine the effectiveness of psycho-educational group therapy on a sample of dual diagnosis patients...
February 20, 2018: Journal of Dual Diagnosis
https://www.readbyqxmd.com/read/29461795/nanoengineered-ionic-covalent-entanglement-nice-bioinks-for-3d-bioprinting
#10
David Chimene, Charles W Peak, James Gentry, James K Carrow, Lauren M Cross, Eli Mondragon, Guinea B C Cardoso, Roland Kaunas, Akhilesh K Gaharwar
We introduce an enhanced nanoengineered ionic covalent entanglement (NICE) bioink for the fabrication of mechanically stiff and elastomeric 3D biostructures. NICE bioink formulations combine nanocomposite and ionic covalent entanglement (ICE) strengthening mechanisms to print customizable cell-laden constructs for tissue engineering with high structural fidelity and mechanical stiffness. Nanocomposite and ICE strengthening mechanisms complement each other through their synergistic interactions, improving mechanical strength, elasticity, toughness, and flow properties beyond the sum of the effects of both reinforcement techniques alone...
February 20, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29460356/broadening-the-impact-of-developmental-neuroscience-on-the-study-of-adolescence
#11
Andrew J Fuligni, Mirella Dapretto, Adriana Galván
Having been a significance source of the renewed interested in the adolescent period, developmental neuroscience now needs to build upon its achievements to date and expand in several areas in order to broaden its impact upon the field. Addressing both typical and atypical development, examining the interaction between brain development and the social environment, studying change over time, and including attention to population diversity can help to produce a truly integrative science of adolescent development...
March 2018: Journal of Research on Adolescence: the Official Journal of the Society for Research on Adolescence
https://www.readbyqxmd.com/read/29455697/meaningful-ways-of-understanding-and-measuring-change-for-people-with-borderline-personality-disorder-a-thematic-analysis
#12
Louise McCusker, Marie-Louise Turner, Georgina Pike, Helen Startup
BACKGROUND: The effective treatment of Borderline Personality Disorder (BPD) presents healthcare providers with a significant challenge. The evidence base remains limited partially due to a lack of professional consensus and service user involvement regarding ways of measuring change. As a result, the limited evidence that is available draws on such a wide range of outcome measures, that comparison across treatment types is hindered, maintaining a lack of clarity regarding the clinical needs of this group...
February 19, 2018: Behavioural and Cognitive Psychotherapy
https://www.readbyqxmd.com/read/29453841/beyond-cost-benefit-analysis-in-the-governance-of-synthetic-biology
#13
Wendell Wallach, Marc Saner, Gary Marchant
For many innovations, oversight fits nicely within existing governance mechanisms; nevertheless, others pose unique public health, environmental, and ethical challenges. Synthetic artemisinin, for example, has many precursors in laboratory-developed drugs that emulate natural forms of the same drug. The policy challenges posed by synthetic artemisinin do not differ significantly in kind from other laboratory-formulated drugs. Synthetic biofuels and gene drives, however, fit less clearly into existing governance structures...
January 2018: Hastings Center Report
https://www.readbyqxmd.com/read/29453511/developing-new-age-specific-prostate-specific-antigen-thresholds-for-testing-for-prostate-cancer
#14
Rebecca Gilbert, Kate Tilling, Richard M Martin, J Athene Lane, Michael Davis, Freddie C Hamdy, David E Neal, Jenny L Donovan, Chris Metcalfe
PURPOSE: To examine whether age-related reference ranges for "normal" prostate-specific antigen (PSA) change (determined in men without prostate cancer) can be used to identify men at high risk of having prostate cancer. METHODS: Subjects were men aged 50-69 years with PSA < 10 ng/mL from the UK-based Prostate Testing for cancer and Treatment (ProtecT) study. Men with prostate cancer were categorized as high or low risk of progression (Low risk: Gleason score ≤ 6 and stage T1-T2a; High risk: Gleason score 7-10 or stage T2C)...
February 16, 2018: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/29452428/illness-severity-predicts-death-and-brain-injury-in-asphyxiated-newborns-treated-with-hypothermia
#15
Hui Wang, Marc Beltempo, Emmanouil Rampakakis, Priscille-Nice Sanon, Stephanie Barbosa Vargas, Julie Maluorni, Christine Saint-Martin, Pia Wintermark
OBJECTIVE: To determine if illness severity during the first days of life predicts adverse outcome in asphyxiated newborns treated with hypothermia. STUDY DESIGN: We conducted a retrospective cohort study of asphyxiated newborns treated with hypothermia. Illness severity was calculated daily during the first 4 days of life using the Score for Neonatal Acute Physiology II (SNAP-II score). Adverse outcome (death and/or brain injury) was recorded. Differences in SNAP-II scores between the newborns with and without adverse outcome were assessed...
February 16, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29451407/advancements-in-drug-development-for-diarrhea-predominant-irritable-bowel-syndrome
#16
Giovanni Dothel, Maria Raffaell Barbaro, Emanuel Raschi, Giovanni Barbara, Fabrizio De Ponti
Introduction Diarrhea-predominant irritable bowel syndrome (IBS-D) is a common disorder characterized by a complex pathophysiology hampering optimal targeted drug development. Recent advances in our understanding of key underlying mechanisms prompted novel therapeutics including novel pharmacological approaches. Areas covered This review summarizes the latest advancements in the pipeline of IBS-D drugs focusing on new pharmacological targets, efficacy and safety of medicinal products considering the recent harmonization of regulatory requirements by the FDA and the EMA...
February 16, 2018: Expert Opinion on Investigational Drugs
https://www.readbyqxmd.com/read/29449220/nice-recommends-kidney-cancer-drug-likely-to-be-less-effective-than-current-treatments-after-price-deal
#17
Susan Mayor
No abstract text is available yet for this article.
February 15, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29448987/the-refeeding-syndrome-importance-of-phosphorus
#18
REVIEW
Marta Araujo Castro, Clotilde Vázquez Martínez
Refeeding syndrome (RS) is a complex disease that occurs when nutritional support is initiated after a period of starvation. The hallmark feature is the hypophosphataemia, however other biochemical abnormalities like hypokalaemia, hypomagnesaemia, thiamine deficiency and disorder of sodium and fluid balance are common. The incidence of RS is unknown as no universally accepted definition exists, but it is frequently underdiagnosed. RS is a potentially fatal, but preventable, disorder. The identification of patients at risk is crucial to improve their management...
February 12, 2018: Medicina Clínica
https://www.readbyqxmd.com/read/29446055/which-costs-matter-costs-included-in-economic-evaluation-and-their-impact-on-decision-uncertainty-for-stable-coronary-artery-disease
#19
James Lomas, Miqdad Asaria, Laura Bojke, Chris P Gale, Gerry Richardson, Simon Walker
BACKGROUND: Variation exists in the resource categories included in economic evaluations, and National Institute for Health and Care Excellence (NICE) guidance suggests the inclusion only of costs related to the index condition or intervention. However, there is a growing consensus that all healthcare costs should be included in economic evaluations for Health Technology Assessments (HTAs), particularly those related to extended years of life. OBJECTIVE AND METHODS: We aimed to quantify the impact of a range of cost categories on the adoption decision about a hypothetical intervention, and uncertainty around that decision, for stable coronary artery disease (SCAD) based on a dataset comprising 94,966 patients...
February 14, 2018: PharmacoEconomics Open
https://www.readbyqxmd.com/read/29442332/issues-related-to-the-frequency-of-exploratory-analyses-by-evidence-review-groups-in-the-nice-single-technology-appraisal-process
#20
Eva Kaltenthaler, Christopher Carroll, Daniel Hill-McManus, Alison Scope, Michael Holmes, Stephen Rice, Micah Rose, Paul Tappenden, Nerys Woolacott
BACKGROUND: Evidence Review Groups (ERGs) critically appraise company submissions as part of the National Institute for Health and Care Excellence (NICE) Single Technology Appraisal (STA) process. As part of their critique of the evidence submitted by companies, the ERGs undertake exploratory analyses to explore uncertainties in the company's model. The aim of this study was to explore pre-defined factors that might influence or predict the extent of ERG exploratory analyses. OBJECTIVE: The aim of this study was to explore predefined factors that might influence or predict the extent of ERG exploratory analyses...
June 2017: PharmacoEconomics Open
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