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Alfred Winter, Sebastian Stäubert, Danny Ammon, Stephan Aiche, Oya Beyan, Verena Bischoff, Philipp Daumke, Stefan Decker, Gert Funkat, Jan E Gewehr, Armin de Greiff, Silke Haferkamp, Udo Hahn, Andreas Henkel, Toralf Kirsten, Thomas Klöss, Jörg Lippert, Matthias Löbe, Volker Lowitsch, Oliver Maassen, Jens Maschmann, Sven Meister, Rafael Mikolajczyk, Matthias Nüchter, Mathias W Pletz, Erhard Rahm, Morris Riedel, Kutaiba Saleh, Andreas Schuppert, Stefan Smers, André Stollenwerk, Stefan Uhlig, Thomas Wendt, Sven Zenker, Wolfgang Fleig, Gernot Marx, André Scherag, Markus Löffler
INTRODUCTION: This article is part of the Focus Theme of Methods of Information in Medicine on the German Medical Informatics Initiative. "Smart Medical Information Technology for Healthcare (SMITH)" is one of four consortia funded by the German Medical Informatics Initiative (MI-I) to create an alliance of universities, university hospitals, research institutions and IT companies. SMITH's goals are to establish Data Integration Centers (DICs) at each SMITH partner hospital and to implement use cases which demonstrate the usefulness of the approach...
July 2018: Methods of Information in Medicine
Vinidh Paleri, Hannah Fox, Stuart Winter
Transoral robotic surgery has shown significant promise in the management of oropharyngeal cancer since its description in 2007. The oncological efficacy of this procedure has been proven in several single-centre studies, multicentre collaborative publications and systematic reviews. The rapid take-up of transoral robotic surgery shows greater acceptance by professionals and is associated with a relatively short learning curve. This overview discusses the rationale and principles underlying the use of transoral robotic surgery in primary and recurrent oropharyngeal cancer and the emerging role for this technique in diagnosing the unknown primary site, and summarizes ongoing research in this field...
July 17, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
K J MacLeod, M J Sheriff, D C Ensminger, D A S Owen, T Langkilde
Organisms are continuously encountering both predictable and unpredictable ecological stressors within their environment. The activation of the hypothalamic-pituitary-adrenal (stress) axis is a fundamental process allowing animals to cope with and respond to such encounters. A main consequence of HPA axis activation is the release of glucocorticoid hormones. Although short-term glucocorticoid elevations lead to changes in physiological and behavioral processes that are often adaptive, our understanding of fitness consequences of repeated acute elevations in glucocorticoid hormones over a longer time period is largely lacking...
July 14, 2018: General and Comparative Endocrinology
Rong Cao, Haijun Zhang, Lijuan Zhao, Yichi Zhang, Ningbo Geng, Man Teng, Lili Zou, Yuan Gao, Yuwen Ni, Qiang Fu, Jiping Chen
Haze is a serious pollution problem during the wintertime in North China. In this study, we investigated how the periodic cycle of winter haze events affect the environmental behaviors of two typical persistent organic pollutants, namely, polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and polybrominated diphenyl ethers (PBDEs), in the atmosphere of a typical megacity, Beijing. The average atmospheric concentrations of the total di- to octa-CDD/Fs (∑PCDD/Fs: 378.0 pg/m3) and the total mono- to nona-BDEs (∑9hPBDEs: 166...
July 17, 2018: Environmental Science & Technology
Brian B Oakley, Elton J R Vasconcelos, Pedro P V P Diniz, Kimberly N Calloway, Ella Richardson, Richard J Meinersmann, Nelson A Cox, Mark E Berrang
Next-generation DNA sequencing is rapidly becoming a powerful tool for food animal management. One valuable use of this technology is to re-examine long-standing observations of performance differences associated with animal husbandry practices to better understand how these differences may be modulated by the gastrointestinal (GI) microbiome. The influences of environmental parameters such as air temperature and relative humidity on broiler chicken performance have commonly been observed, but how the GI microbiome may respond to seasonal environmental changes remains largely unknown...
July 17, 2018: Poultry Science
Ahmad M Awajan, Mohd Tahir Ismail, S Al Wadi
Many researchers documented that the stock market data are nonstationary and nonlinear time series data. In this study, we use EMD-HW bagging method for nonstationary and nonlinear time series forecasting. The EMD-HW bagging method is based on the empirical mode decomposition (EMD), the moving block bootstrap and the Holt-Winter. The stock market time series of six countries are used to compare EMD-HW bagging method. This comparison is based on five forecasting error measurements. The comparison shows that the forecasting results of EMD-HW bagging are more accurate than the forecasting results of the fourteen selected methods...
2018: PloS One
Yan Kang, Huijun Xie, Jian Zhang, Congcong Zhao, Wengang Wang, Ying Guo, Zizhang Guo
The synergy of Tubifex tubifex (T. tubifex) and mussels on SFCWs (named SFCW-MT) performance was well studied in laboratory throughout a year. The SFCW-MT were steady operated with high TN and TP treatment, with the removal efficiencies of 37.85 ± 5.22% and 39.26 ± 5.20% even in winter. The mussels had excellent NH4 -N removal efficiency, and avoid the shortage of NH4 -N removal with T. tubifex in winter. Simultaneously, the SFCW-MT improved the NO3 -N treatment by 51% than that in control group. The plant growth was improved in SFCW-MT, which reflected in the improvement of total chlorophyll contents and plant heights...
July 13, 2018: Ecotoxicology and Environmental Safety
Mariana C Arcaya, Alina Schnake-Mahl, Andrew Binet, Shannon Simpson, Maggie Super Church, Vedette Gavin, Bill Coleman, Shoshanna Levine, Annika Nielsen, Leigh Carroll, Sanouri Ursprung, Ben Wood, Halley Reeves, Barry Keppard, Noemie Sportiche, Jessie Partirdge, Jose Figueora, Austin Frakt, Mariel Alfonzo, Dina Abreu, Tatiana Abreu, Trena Ambroise, Eric Andrade, Eduardo Barrientos, Arnetta Baty, Carl Baty, Katrina Benner, Clifton Bennett, Amy Blanchette, Roseann Bongiovanni, Olivia Cardile, Cristian Corchado, Caleb Dixon, Crystal Dodson, Juan Dominguez, Mytha Durena, Yrma Fiestas, Josee Genty, Nicole Graffam, Adela Gonzalez, Emma Grigsby, Patricia Hayden, Stephanie Hernandez Alvado, Zuleyka Hernandez, Isaac Hodes, Jarred Johnson, Kathryn Keefe, Krystle Latimer, Shoshanna Levine, Christina Logg, Nelson Martinez, Khadijah Mboup, Doug McPhorson, Steve Meacham, Daynaba Mohammed, Emily Moss, Annika Nielsen, Kathleen O'Brien, Lisa Owens, Jessie Partridge, Lillie Pearl Johnson, Maria Belen Power, Taylee Rebelo, Ronel Remy, Gail Roderigues, Qamar Sabtow, Clarisa Sanchez, Andrew Seeder, Ramon Sepulveda, Noemie Sportiche, Sanouri Ursprung, Emma West, Leah Winters, Ben Wood, Tremayne Youmans
The health implications of urban development, particularly in rapidly changing, low-income urban neighborhoods, are poorly understood. We describe the Healthy Neighborhoods Study (HNS), a Participatory Action Research study examining the relationship between neighborhood change and population health in nine Massachusetts neighborhoods. Baseline data from the HNS survey show that social factors, specifically income insecurity, food insecurity, social support, experiencing discrimination, expecting to move, connectedness to the neighborhood, and local housing construction that participants believed would improve their lives, identified by a network of 45 Resident Researchers exhibited robust associations with self-rated and mental health...
July 6, 2018: Health & Place
John Hesselschwerdt, Karl M Wantzen
European freshwater ecosystems are increasingly invaded by exotic animal and plant species. Apart from increased connectivity between previously separated watersheds, the increasing temperature of the hydrosystems favors the spread of exotic species. The freshwater fauna of Central Europe is still shaped by the cold-adapted animal assemblages resulting from the last glaciation. It is less diverse, and the species are putatively less performant competitors, compared to the warm-adapted, species-rich fauna of the Ponto-Caspian realm, from which many current aquatic invaders are coming...
July 13, 2018: Science of the Total Environment
An Liu, Nian Hong, Panfeng Zhu, Yuntao Guan
Benzene series (BTEX) pollutants which are generated by traffic can deposit (build-up) on urban road surfaces. When they are washed-off by stormwater runoff, BTEX are toxic to ecological and human health if the stormwater is reused. To understand the risk posed by BTEX, it is essential to have an in-depth investigation on BTEX build-up, one of the most important stormwater pollutant processes. This study analysed the relationship between BTEX build-up and BTEX build-up's influential factors. The outcomes confirmed an important role of climatic factors (particularly temperature) on influencing BTEX build-up...
July 12, 2018: Environmental Pollution
Xing-Pan Guo, Xinran Liu, Zuo-Shun Niu, Da-Pei Lu, Sai Zhao, Xiao-Li Sun, Jia-Yuan Wu, Yu-Ru Chen, Fei-Yun Tou, Lijun Hou, Min Liu, Yi Yang
Antibiotics resistance genes (ARGs) are considered as an emerging pollutant among various environments. As a sink of ARGs, a comprehensive study on the spatial and temporal distribution of ARGs in the estuarine sediments is needed. In the present study, six ARGs were determined in sediments taken along the Yangtze Estuary temporally and spatially. The sulfonamides, tetracyclines and fluoroquinolones resistance genes including sul1, sul2, tetA, tetW, aac(6')-Ib, and qnrS, were ubiquitous, and the average abundances of most ARGs showed significant seasonal differences, with relative low abundances in winter and high abundances in summer...
June 29, 2018: Environmental Pollution
Milena Rusin, Janina Gospodarek, Aleksandra Nadgórska-Socha, Gabriela Barczyk, Elżbieta Boligłowa, Marzena Dabioch
The aim of the study was to determine the effects of various petroleum-derived substances (PDSs), namely petrol, diesel fuel, and spent engine oil, on life history traits of the bird cherry-oat aphid Rhopalosiphum padi L., and on the growth and chemical composition of its host plant-winter wheat Triticum aestivum L. Each substance was tested separately, using two concentrations (9 and 18 g kg-1 ). Plants were cultivated in both control and contaminated soils. In early October 2013, soil was contaminated and after 1 week, winter wheat seeds, 'Batuta' cultivar, were sown...
July 16, 2018: Environmental Science and Pollution Research International
Eike Luedeling
Calculating many agroclimatic metrics, e.g., chill or heat accumulation in orchards, requires continuous records of hourly temperature. Such records are often unavailable, with farm managers and researchers relying on daily data or hourly records with gaps. While procedures for generating idealized temperature curves exist, interpolating hourly records has long been a challenge. The SolveHours procedure combines measured hourly temperatures, idealized daily temperature curves and proxy data to fill gaps in such records...
July 16, 2018: International Journal of Biometeorology
Wesley Chan, Si Xi Zhao, Aaron Winter, Hesham Lakosha, R Rishi Gupta
Purpose: Hypertensive emergency usually presents to ophthalmologists in the form of hypertensive retinopathy. We present a case of hypertensive emergency that presented as bilateral transient myopic shift due to ciliary body detachment in the absence of any retinal pathology. The purpose of this paper is to showcase another ocular manifestation of hypertensive emergency. Observations: A 35 year-old female with a blood pressure of 192/114 mmHg presented to the emergency department with headache and acute onset blurry vision...
September 2018: American Journal of Ophthalmology Case Reports
Marko S Laaksonen, Malin Jonsson, Hans-Christer Holmberg
The biathlon, combining cross-country ski skating with rifle marksmanship, has been an Olympic event since the Winter Games in Squaw Valley, United States, in 1960. As a consequence of replacing the classical with the skating technique in the 1980s, as well as considerable improvements in equipment and preparation of ski tracks and more effective training, the average biathlon skiing speed has increased substantially. Moreover, the mass-start, pursuit, and sprint races have been introduced. Indeed, two of the four current individual Olympic biathlon competitions involve mass-starts, where tactics play a major role and the outcome is often decided during the last round of shooting or final sprint...
2018: Frontiers in Physiology
Sarah Ineson, Magdalena A Balmaseda, Michael K Davey, Damien Decremer, Nick J Dunstone, Margaret Gordon, Hong-Li Ren, Adam A Scaife, Antje Weisheimer
Early in 2014 several forecast systems were suggesting a strong 1997/98-like El Niño event for the following northern hemisphere winter 2014/15. However the eventual outcome was a modest warming. In contrast, winter 2015/16 saw one of the strongest El Niño events on record. Here we assess the ability of two operational seasonal prediction systems to forecast these events, using the forecast ensembles to try to understand the reasons underlying the very different development and outcomes for these two years...
July 16, 2018: Scientific Reports
Karl Erik Müller, Ricardo Andrade Zampieri, Juliana Ide Aoki, Sandra Marcia Muxel, Audun Helge Nerland, Lucile Maria Floeter-Winter
BACKGROUND: The leishmaniases comprise a spectrum of clinical manifestations caused by different species of Leishmania. Identification of species is important for diagnosis, treatment and follow-up management. However, there is no gold standard for species identification. High resolution melting analysis (HRM) offers a possibility to differentiate Leishmania species without the need for processing of the PCR-product. The amino acid permease 3 (aap3) gene is an exclusive target for trypanosomatids and is conserved among Leishmania spp...
July 16, 2018: Parasites & Vectors
Cornelia Betsch, Constanze Rossmann, Mathias W Pletz, Horst C Vollmar, Antje Freytag, Ole Wichmann, Regina Hanke, Wolfgang Hanke, Dorothee Heinemeier, Philipp Schmid, Sarah Eitze, Winja Weber, Anne Reinhardt, Nora K Küpke, Christina Forstner, Carolin Fleischmann-Struzek, Anna Mikolajetz, Josephine Römhild, Julia Neufeind, Thorsten Rieck, Kasia Suchecka, Konrad Reinhart
BACKGROUND: Influenza and pneumococcal vaccination can prevent disease and potentially life-threatening complications like sepsis. Elderly people have an increased risk of severe disease and therefore constitute a major target group for vaccination. To increase vaccination coverage, targeted interventions are needed that take theory-based specific determinants of vaccination behaviour into account. Moreover, message and campaign design should consider specific age-related characteristics (e...
July 16, 2018: BMC Public Health
Wen-Kuan Liu, Qian Liu, De-Hui Chen, Wei-Ping Tan, Yong Cai, Shu-Yan Qiu, Duo Xu, Chi Li, Xiao Li, Zheng-Shi Lin, Rong Zhou
BACKGROUND: Human bocavirus 1 (HBoV1) is an important cause of acute respiratory illness (ARI), yet the epidemiology and effect of meteorological conditions on infection is not fully understood. To investigate the distribution of HBoV1 and determine the effect of meteorological conditions, hospitalized pediatric patients were studied in a subtropical region of China. METHODS: Samples from 11,399 hospitalized pediatric patients (≤14 years old), with ARI were tested for HBoV1 and other common respiratory pathogens using real-time PCR, between July 2009 and June 2016...
July 16, 2018: BMC Infectious Diseases
Daniel E Winkler, Jennifer R Gremer, Kenneth J Chapin, Melanie Kao, Travis E Huxman
PREMISE OF STUDY: Mechanisms by which invasive species succeed across multiple novel environmental contexts are poorly understood. Functional traits show promise for identifying such mechanisms, yet we lack knowledge of which functional traits are critical for success and how they vary across invaded ranges and with environmental features. We evaluated the widespread recent invasion of Sahara mustard (Brassica tournefortii) in the southwestern United States to understand the extent of functional trait variation across the invaded range and how such variation is related to spatial and climatic gradients...
July 16, 2018: American Journal of Botany
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