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https://www.readbyqxmd.com/read/29150864/seeing-is-believing-a-review-of-apheresis-therapy-in-the-treatment-of-ophthalmologic-disease
#1
Brendan C Graham, Jose S Pulido, Jeffrey L Winters
Apheresis procedures have a role in treatment of disparate diseases involving many different organ systems. Often the disease processes where apheresis plays a role in treatment are considered "orphan diseases"-relatively rare disease processes that lack specific pharmaceutical agents or established treatment protocols. Many of these disease processes can affect the eye with devastating results for the eyesight of these patients. The unique ability of apheresis to affect disease by modifying blood plasma and modulating disease-causing agents therein renders apheresis procedures valuable tools in the treatment of certain ophthalmologic diseases...
November 18, 2017: Journal of Clinical Apheresis
https://www.readbyqxmd.com/read/29150823/metabolic-dynamics-and-physiological-adaptation-of-panax-ginseng-during-development
#2
Yu-Jin Kim, Sung Chul Joo, Jianxin Shi, Chaoyang Hu, Sheng Quan, Jianping Hu, Johan Sukweenadhi, Padmanaban Mohanan, Deok-Chun Yang, Dabing Zhang
The dynamics of metabolites from leaves to roots of Panax ginseng during development has revealed the tissue-specific and year-specific metabolic networks. Being an essential Oriental medicinal plant, ginseng (Panax ginseng Meyer) is a slow-growing perennial herb-accumulating pharmaceutically active metabolites such as ginsenosides in roots during growth. However, little is known about how ginseng plants survive in the harsh environments such as winter cold and summer heat for a longer period and accumulates those active metabolites as the plant grows...
November 17, 2017: Plant Cell Reports
https://www.readbyqxmd.com/read/29150801/soil-physical-properties-response-to-tillage-practices-during-summer-fallow-of-dryland-winter-wheat-field-on-the-loess-plateau
#3
Jian-Fu Xue, Ai-Xia Ren, Hui Li, Zhi-Qiang Gao, Tian-Qing Du
Soil physical properties are a greatly important part of the soil and indicator of soil quality, which can directly affect soil nutrient turnover and crop yields in dryland. This study was carried out with three tillage practices during the summer fallow season since 2011, including no tillage (NT), plow tillage (PT), and subsoiling (ST) in dryland winter wheat fields of the Loess Plateau. Results showed that soil tillage during the summer fallow had a small effect on soil bulk density (ρ b) in the 0-50-cm soil profile before sowing and after harvesting of winter wheat...
November 17, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29150762/seasonal-influence-on-adherence-to-and-effects-of-an-interval-walking-training-program-on-sedentary-female-college-students-in-japan
#4
Aiko Tanabe, Shizue Masuki, Ken-Ichi Nemoto, Hiroshi Nose
Habitual exercise training is recommended to young people for their health promotion, but adherence may be influenced by atmospheric temperature (T a ) if performed outdoors. We compared the adherence to and the effects of a home-based interval walking training (IWT) program on sedentary female college students between winter and summer. For summer training over 176 days, 48 subjects (18-22 years old) were randomly divided into two groups: the control group (CNTsummer, n = 24), which maintained a sedentary lifestyle as before, and the IWT group (IWTsummer, n = 24), which performed IWT while energy expenditure was monitored by accelerometry...
November 17, 2017: International Journal of Biometeorology
https://www.readbyqxmd.com/read/29150676/severe-pollution-in-china-amplified-by-atmospheric-moisture
#5
Xuexi Tie, Ru-Jin Huang, Junji Cao, Qiang Zhang, Yafang Cheng, Hang Su, Di Chang, Ulrich Pöschl, Thorsten Hoffmann, Uli Dusek, Guohui Li, Douglas R Worsnop, Colin D O'Dowd
In recent years, severe haze events often occurred in China, causing serious environmental problems. The mechanisms responsible for the haze formation, however, are still not well understood, hindering the forecast and mitigation of haze pollution. Our study of the 2012-13 winter haze events in Beijing shows that atmospheric water vapour plays a critical role in enhancing the heavy haze events. Under weak solar radiation and stagnant moist meteorological conditions in winter, air pollutants and water vapour accumulate in a shallow planetary boundary layer (PBL)...
November 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29150554/cancer-cells-induce-interleukin-22-production-from-memory-cd4-t-cells-via-interleukin-1-to-promote-tumor-growth
#6
Cornelia Voigt, Peter May, Adrian Gottschlich, Anamarija Markota, Daniel Wenk, Inga Gerlach, Sebastian Voigt, Georgios T Stathopoulos, Kristina A M Arendt, Constanze Heise, Felicitas Rataj, Klaus-Peter Janssen, Melanie Königshoff, Hauke Winter, Isabelle Himsl, Wolfgang E Thasler, Max Schnurr, Simon Rothenfußer, Stefan Endres, Sebastian Kobold
IL-22 has been identified as a cancer-promoting cytokine that is secreted by infiltrating immune cells in several cancer models. We hypothesized that IL-22 regulation would occur at the interface between cancer cells and immune cells. Breast and lung cancer cells of murine and human origin induced IL-22 production from memory CD4(+) T cells. In the present study, we found that IL-22 production in humans is dependent on activation of the NLRP3 inflammasome with the subsequent release of IL-1β from both myeloid and T cells...
November 17, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29150339/hair-concentration-of-trace-elements-and-growth-in-homeless-children-aged-6years-results-from-the-enfams-study
#7
Lucia Fábelová, Stéphanie Vandentorren, Cécile Vuillermoz, Robert Garnier, Sandrine Lioret, Jérémie Botton
BACKGROUND: Growth is an important indicator of health in early childhood. This is a critical developmental period, during which a number of factors, including exposure to metals, might play a role in later physical and metabolic functions. OBJECTIVE: To study the association between exposure to arsenic (As), cadmium (Cd), mercury (Hg), lead (Pb) and selenium (Se), and physical growth of children from homeless families aged <6years. METHODS: This study was based on data of the cross-sectional survey (ENFAMS), which was conducted by the Observatoire du Samu Social on a random sample of homeless sheltered families in the Paris region during winter 2013...
November 14, 2017: Environment International
https://www.readbyqxmd.com/read/29149966/seasonal-variation-of-vitamin-d-status-in-long-term-kidney-transplant-recipients
#8
J Wilimborek, M Nowicki, I Kurnatowska
BACKGROUND: There is little information about circannual rhythm of vitamin D level in kidney transplantation (KTx) patients. MATERIAL AND METHODS: In 71 patients (27 females; 44 males) in the long term after KTx (5.5 ± 2.6 years) during the winter and summer months plasma concentration of 25-hydroxyvitamin D (25(OH)D), 1,25-hydroxyvitamin D, parathormone (PTH), fibroblast growth factor 23 (FGF-23), calcium, and phosphorus were assessed. Vitamin D status was classified according to 25(OH)D level (ie, insufficiency, ≤30 ng/mL; deficiency, <15 ng/mL)...
November 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/29149858/famine-food-of-vegetal-origin-consumed-in-the-netherlands-during-world-war-ii
#9
Tom Vorstenbosch, Ingrid de Zwarte, Leni Duistermaat, Tinde van Andel
BACKGROUND: Periods of extreme food shortages during war force people to eat food that they normally do not consider edible. The last time that countries in Western Europe experienced severe scarcities was during World War II. The so-called Dutch famine or Hunger Winter (1944-1945) made at least 25,000 victims. The Dutch government took action by opening soup kitchens and providing information on wild plants and other famine food sources in "wartime cookbooks." The Dutch wartime diet has never been examined from an ethnobotanical perspective...
November 17, 2017: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/29149737/source-apportionment-of-black-carbon-during-winter-in-beijing
#10
Yue Liu, Caiqing Yan, Mei Zheng
Black carbon (BC) in PM2.5 was measured at an urban site in Beijing during winter 2015 using an aethalometer. The characteristics and sources of BC during pollution episodes and clean days were analyzed. The average hourly mass concentration of BC during the study period was 5.31±6.27μg/m(3). BC was highly correlated with PM2.5 (R(2)=0.80), with its concentration ranging from 0.17μg/m(3) in clean days to 35.33μg/m(3) in haze days. Source apportionment results showed that the average contribution of liquid fuel source (e...
November 14, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29149338/multiplex-respiratory-virus-testing-for-antimicrobial-stewardship-a-prospective-assessment-of-antimicrobial-use-and-clinical-outcomes-among-hospitalized-adults
#11
Makeda Semret, Ian Schiller, Barbara Ann Jardin, Charles Frenette, Vivian G Loo, Jesse Papenburg, Shelly A McNeil, Nandini Dendukuri
Background: Respiratory tract infections are frequent causes of hospitalization and initiation of empirical antimicrobial therapy. Testing for a broad panel of respiratory viruses has been advocated as a useful tool for antibiotic stewardship. We conducted a prospective observational study to assess the impact of rapid viral test results on antimicrobial prescriptions and clinical outcomes among hospitalized adults. Methods: Eight hundred patients admitted with respiratory symptoms were tested by a 12-virus respiratory panel (RVP) during 3 consecutive winters in Montreal, Canada...
November 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29148653/novel-indices-of-meterological-drivers-of-west-nile-virus-in-ohio-culex-species-mosquitoes-from-2002-2006
#12
Paul A Rosalie, Michael Bisesi
Novel indices were developed representing estimated stages in the mosquito life cycle and its ecology, and informed with meteorological data. We used descriptive statistics to identify relationships between meteorological/ecological trends and peak infection rates (IRs), and mixed model linear regression to identify meteorological/ecological trends that were significantly associated with increases in mosquito IRs. Results showed increased mean weekly temperature as a significant driver of increased IRs between 2002 and 2006 during oviposition (the trapping week); the gonotrophic cycle; the egg, larvae, and pupae stage; the development of oviposition sites; and during the over-winter months preceding trapping...
April 2017: Journal of Environmental Health
https://www.readbyqxmd.com/read/29148411/vitamin-d-status-in-spondyloarthritis-results-of-the-asas-comospa-international-study
#13
Sílvia Fernandes, Adrien Etcheto, Désirée van der Heijde, Robert Landewé, Filip van den Bosch, Maxime Dougados, Anna Moltó
OBJECTIVES: Spondyloarthritis (SpA) encompasses both bone production and bone loss, and the latter is particularly linked to inflammation. Vitamin D deficiency has been associated with several inflammatory conditions (i.e. cardiovascular disease, rheumatoid arthritis), but it has been poorly evaluated in SpA patients. We aimed to a) describe the prevalence of vitamin D deficiency in SpA patients worldwide; b) compare SpA patients with and without vitamin D deficiency in terms of disease phenotype, activity severity and comorbidities...
November 16, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29148372/deaths-among-wild-birds-during-highly-pathogenic-avian-influenza-a-h5n8-virus-outbreak-the-netherlands
#14
Erik Kleyheeg, Roy Slaterus, Rogier Bodewes, Jolianne M Rijks, Marcel A H Spierenburg, Nancy Beerens, Leon Kelder, Marjolein J Poen, Jan A Stegeman, Ron A M Fouchier, Thijs Kuiken, Henk P van der Jeugd
During autumn-winter 2016-2017, highly pathogenic avian influenza A(H5N8) viruses caused mass die-offs among wild birds in the Netherlands. Among the ≈13,600 birds reported dead, most were tufted ducks (Aythya fuligula) and Eurasian wigeons (Anas penelope). Recurrence of avian influenza outbreaks might alter wild bird population dynamics.
December 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29146767/pharmacists-delivered-60-more-flu-vaccines-through-nhs-scheme-last-winter-figures-show
#15
Gareth Iacobucci
No abstract text is available yet for this article.
November 16, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29145595/synchrony-weather-and-cycles-in-southern-pine-beetle-coleoptera-curculionidae
#16
John D Reeve
Spatial synchrony and cycles are common features of forest insect pests, but are often studied as separate phenomenon. Using time series of timber damage caused by Dendroctonus frontalis Zimmermann (Coleoptera: Curculionidae) (southern pine beetle) in 10 states within the southern United States, this study examines synchrony in D. frontalis abundance, the synchronizing effects of temperature extremes, and the evidence for shared cycles among state populations. Cross-correlation and cluster analyses are used to quantify synchrony across a range of geographic distances and to identify groups of states with synchronous dynamics...
November 14, 2017: Environmental Entomology
https://www.readbyqxmd.com/read/29145482/combination-of-ultrasound-and-rtpa-enhances-fibrinolysis-in-an-in-vitro-clot-system
#17
Julia Masomi-Bornwasser, Philipp Winter, Hendrik Müller-Werkmeister, Susanne Strand, Jochem König, Oliver Kempski, Florian Ringel, Sven R Kantelhardt, Naureen Keric
BACKGROUND: Catheter-based lysis with recombinant tissue plasminogen activator (rtPA) is a well-established therapy for spontaneous intracerebral hemorrhage (ICH). The effectiveness of this therapy can be increased with ultrasound, but the optimal conditions are not yet clearly established. Using a novel in vitro system of blood clots previously developed by our group, we investigated various parameters of intralesional sonothrombolysis using an endosonography catheter in combination with rtPA...
2017: PloS One
https://www.readbyqxmd.com/read/29145392/conservation-of-a-microrna-cluster-in-parasitic-nematodes-and-profiling-of-mirnas-in-excretory-secretory-products-and-microvesicles-of-haemonchus-contortus
#18
Henry Y Gu, Neil D Marks, Alan D Winter, William Weir, Thomas Tzelos, Tom N McNeilly, Collette Britton, Eileen Devaney
microRNAs are small non-coding RNAs that are important regulators of gene expression in a range of animals, including nematodes. We have analysed a cluster of four miRNAs from the pathogenic nematode species Haemonchus contortus that are closely linked in the genome. We find that the cluster is conserved only in clade V parasitic nematodes and in some ascarids, but not in other clade III species nor in clade V free-living nematodes. Members of the cluster are present in parasite excretory-secretory products and can be detected in the abomasum and draining lymph nodes of infected sheep, indicating their release in vitro and in vivo...
November 16, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29145137/uncertainty-in-positive-matrix-factorization-solutions-for-pahs-in-surface-sediments-of-the-yangtze-river-estuary-in-different-seasons
#19
Ruimin Liu, Cong Men, Wenwen Yu, Fei Xu, Qingrui Wang, Zhenyao Shen
To examine the variabilities of source contributions in the Yangtze River Estuary (YRE), the uncertainty based on the positive matrix factorization (PMF) was applied to the source apportionment of the 16 priority PAHs in 120 surface sediment samples from four seasons. Based on the signal-to-noise ratios, the PAHs categorized as "Bad" might drop out of the estimation of bootstrap. Next, the spatial variability of residuals was applied to determine which species with non-normal curves should be excluded. The median values from the bootstrapped solutions were chosen as the best estimate of the true factor contributions, and the intervals from 5th to 95th percentile represent the variability in each sample factor contribution...
October 13, 2017: Chemosphere
https://www.readbyqxmd.com/read/29145132/effect-of-evaporative-weathering-and-oil-sediment-interactions-on-the-fate-and-behavior-of-diluted-bitumen-in-marine-environments-part-1-spill-related-properties-oil-buoyancy-and-oil-particulate-aggregates-characterization
#20
Yujuan Hua, Fatemeh S Mirnaghi, Zeyu Yang, Bruce P Hollebone, Carl E Brown
The fate and behavior of diluted bitumen spilled in marine conditions has recently become a topic of much interest, yet, only limited knowledge is available. One of the major issues of a diluted bitumen spill on water is whether the product will sink, especially when suspended sediment is present in the water column. This study demonstrated how weathering processes influenced the key spill-related properties of a diluted bitumen product (Cold Lake Blend-Winter), and how interaction of diluted bitumen with sediment affected its tendency to float or sink in water...
October 28, 2017: Chemosphere
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