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https://www.readbyqxmd.com/read/28106699/association-between-odontoma-and-impacted-teeth
#1
Gaetano Isola, Marco Cicciù, Luca Fiorillo, Giovanni Matarese
Odontoma is considered to be the most common odontogenic tumor of the oral cavity. Most odontomas are asymptomatic and are discovered during routine radiographic investigations and can cause disturbances in the eruption of the teeth, most commonly delayed eruption or deflection. By a retrospective study design, demographic and clinical data regarding patients who presented odontomas from year 1995 to 2015 were obtained in order and the influence of active therapy on the dentition and on the treatment of impacted teeth was analyzed...
January 18, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28105241/primary-intraosseous-squamous-cell-carcinoma-of-the-mandible-arising-from-an-infected-odontogenic-cyst-a-case-report-and-review-of-the-literature
#2
Koenraad Grisar, Matthias Schol, Esther Hauben, Joseph Schoenaers, Constantinus Politis
Primary intraosseous squamous cell carcinoma (PIOSCC) derived from a odontogenic cyst is a rare form of odontogenic carcinoma. The incidence of carcinomas arising from odontogenic cysts is particularly uncommon and is reported to occur in 1-2 individuals for every 1,000 cases. The present case describes a 25-year-old man who was initially diagnosed with a chronically infected odontogenic cyst of the mandible. Biopsy and subsequent histology revealed the presence of squamous cell carcinoma. Therefore, neck dissection and hemimandibulectomy were performed...
December 2016: Oncology Letters
https://www.readbyqxmd.com/read/28105148/ameloblastic-carcinoma-of-the-maxilla-a-case-report-and-an-updated-review-of-the-literature
#3
Alessandro Moro, Enrico Foresta, Giulio Gasparini, Sandro Pelo, Mario Forcione, Enrico Giuseppe Cristallini, Marco Toraldo, Cardarelli Lorenzo, Marco Falchi, Gianmarco Saponaro
Ameloblastic carcinoma (AC) is an uncommon malignant odontogenic tumor that can be difficult to differentiate from ameloblastoma and can arise directly as an undifferentiated lesion or from a pre-existing benign lesion. The current study presents a novel case of primary maxillary AC and review the literature on AC of the maxilla. The review of the literature indicates that secondary tumors and posterior localization are associated with a higher tendency for recurrence and, often, multiple recurrences. Surgical therapy, eventually followed by radiotherapy, is the treatment modality most frequently applied, while the role of chemotherapy remains unclear...
December 2016: Oncology Letters
https://www.readbyqxmd.com/read/28099232/keratocystic-odontogenic-tumor-involving-the-orbital-apex
#4
Adam R Sweeney, Jasjit K Dillon, Christopher B Chambers
No abstract text is available yet for this article.
January 17, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28089322/a-central-giant-cell-granuloma-in-posterior-part-of-maxilla-a-case-report
#5
Priyanka Garg, Jinendra Jain, Nayana De, Kushal Chatterjee
INTRODUCTION: Central Giant Cell Granuloma (CGCG) is an intraosseous lesion consisting of cellular fibrous tissue that contains multiple foci of hemorrhage, aggregations of multinucleated giant cells and occasionally trabeculae of woven bone1. PRESENTATION OF CASE: we are presenting a case of Central Giant Cell Granuloma on Maxilla. Extra oral examination revealed a diffuse swelling on the left side of face causing slight obliteration of nasio - nasolabial labial fold resulting in facial asymmetry & Intraoral examination shows a purple expansile mass in the region of upper left 26, 27 and 28 edentulous areas...
November 17, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28089087/prevalence-profile-of-odontogenic-cysts-and-tumors-on-brazilian-sample-after-the-reclassification-of-odontogenic-keratocyst
#6
Filipe Jaeger, Mariana Saturnino de Noronha, Maiza Luiza Vieira Silva, Márcio Bruno Figueiredo Amaral, Soraya de Mattos Carmago Grossmann, Martinho Campolina Rebello Horta, Paulo Eduardo Alencar de Souza, Maria Cássia Ferreira de Aguiar, Ricardo Alves Mesquita
PURPOSE: The aim of this study was to evaluate the impact of the reclassification of odontogenic keratocyst (OKC) as a tumor on the prevalence profile of odontogenic cysts (OCs) and odontogenic tumors (OTs). STUDY DESIGN: Two referral Oral and Maxillofacial Pathology services in Brazil were evaluated. All cases diagnosed as OCs or OTs were selected and classified according to the 1992 WHO-classification (cases before 2005 WHO classification of tumors excluding OKC) and the 2005 WHO classification of tumors, going forward including cases of odontogenic keratocyst tumor (KCOT)...
December 18, 2016: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28079309/bioactive-injectable-aggregates-with-nanofibrous-microspheres-and-human-dental-pulp-stem-cells-a-translational-strategy-in-dental-endodontics
#7
I Garzón, M A Martin-Piedra, V Carriel, M Alaminos, X Liu, R D Souza
Regeneration of the pulp-dentin complex with stem cells is a potential alternative to conventional root canal treatments. Human dental pulp stem cells (hDPSCs) have been extensively studied because of their ability to proliferate and differentiate into mineralized dental and nondental tissues. In this work we combined hDPSCs with two types of injectable poly-L-lactic acid (PLLA) microspheres with a nanofibrous or smooth surface to form bioactive injectable aggregates, and examined their ability to promote pulp regeneration in the root canal in an in vivo model...
January 12, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/28064220/gene-expression-analysis-of-cultured-rat-endothelial-cells-after-nd-yag-laser-irradiation-by-affymetrix-genechip-array
#8
Yoshiko Masuda, Satoshi Yokose, Hiroshi Sakagami
Endothelial cells and dental pulp cells enhance osteo-/odontogenic and angiogenic differentiation. In our previous study, rat pulp cells migrated to Nd:YAG laser-irradiated endothelial cells in an insert cell culture system. The purpose of this study was to examine the possible changes in the gene expression of cultured rat aortic endothelial cells after Nd:YAG laser irradiation using affymetrix GeneChip Array. Total RNA was extracted from the cells at 5 h after laser irradiation. Gene expressions were evaluated by DNA array chip...
January 2017: In Vivo
https://www.readbyqxmd.com/read/28060370/diagnosing-the-most-common-odontogenic-cystic-and-osseous-lesions-of-the-jaws-for-the-practicing-pathologist
#9
Robert A Robinson
Odontogenic cysts and osseous lesions are often seen as challenging diagnostic lesions but the majority of them are easily classified. This article outlines the diagnostic features required for separating the most common of odontogenic cysts and select osseous lesions of the jaws. Clinical and radiographic findings of these jaw lesions often lead to a differential diagnosis that only the histologic findings will clarify. Dentigerous cyst, keratocystic odontogenic tumor, and certain ameloblastomas that have cystic change, may have identical radiographic findings, with only separation by their specific histologic features leading to the significantly different treatments required for each...
January 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28054463/kallikrein-related-peptidase-expression-in-odontogenic-cysts-and-tumors-an-immunohistochemical-comparative-study
#10
Mark Roger Darling, Rebecca Woodford, Karl Kevin Cuddy, Linda Jackson-Boeters, Alyssa Hayter, Jeyanth Inkaran, Eleftherios P Diamandis, Zia Khan
AIM: The aim of the present study was to profile the expression of human kallikrein (KLK)-related peptidases (KLK) in odontogenic lesions. METHODS: Paraffin-embedded, formalin-fixed, non-odontogenic (control) and odontogenic lesions were stained for KLK using a standard immunohistochemical technique. The intensity and proportion of epithelial cells stained was scored. Reverse transcription-polymerase chain reaction was utilized to evaluate KLK 1-15 mRNA expression in ameloblastomas...
January 4, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28052640/retrospective-analysis-of-benign-orofacial-tumors-at-a-tertiary-referral-center-in-saudi-arabia
#11
Nandimandalam Venkata Vani, Ali M Idris, Sanaa M Saleh, Faisal M Tubaigy, Fahd A Alharbi, Abubakr A Sharwani, Nabil Tadrus, Saman Warnakulasuriya
AIM: The aim of the present study was to analyze the prevalence of benign tumors of the orofacial region at a tertiary referral center in the south-western region of Saudi Arabia. METHODS: Cases from 2009 to 2014 were retrieved from October 2014 to June 2015 from the archives of the histopathology department of the center. Demographic and clinical details of the patients were recorded. RESULTS: Of the 714 oral and maxillofacial biopsy specimens, 78 (10...
January 4, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28043653/fluctuating-asymmetry-in-dental-and-mandibular-nonmetric-traits-as-evidence-for-childcare-sex-bias-in-19th-20th-century-portugal
#12
L M Marado, A M Silva, J D Irish
Fluctuating asymmetry, often considered a measure of developmental instability, was studied in the dental morphological traits of 600 individuals from among the poorest sectors of society in 19th-20th century Portugal. The aims are to identify and interpret any differences between: (1) males and females, and (2) patterns of distribution among teeth with different odontogenic timings, to assess if any sex bias existed in childcare. Dental and mandibular morphological traits were recorded using the Arizona State University Dental Anthropology System...
December 15, 2016: Homo: Internationale Zeitschrift Für die Vergleichende Forschung Am Menschen
https://www.readbyqxmd.com/read/28038480/intracranial-ameloblastoma-arising-from-the-maxilla-an-interdisciplinary-surgical-approach
#13
Johanna Quick-Weller, Felix Koch, Nazife Dinc, Stephanie Lescher, Peter Baumgarten, Patrick Harter, Friedrich Scheerer, Robert Sader, Volker Seifert, Gerhard Marquardt, Thomas Freiman
Background Ameloblastomas are a rare tumor entity accounting for only 10% of all odontogenic tumors. They mostly originate from the mandible. Only a few cases are known to grow aggressively and to invade the orbit, nasal cavity, or even the brain. Patient and Methods/Case Report We present the case of a 57-year-old patient who was admitted with a huge tumor involving the nasal cavity, the left maxilla, and the anterior fossa. Histologic diagnosis was made by biopsy. A combined two-stage neurosurgical maxillofacial approach was planned...
December 30, 2016: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/28033065/effects-of-bioactive-compounds-on-odontogenic-differentiation-and-mineralization
#14
S Phung, C Lee, C Hong, M Song, J K Yi, R G Stevenson, M K Kang, K-H Shin, N-H Park, R H Kim
Direct pulp capping involves the placement of dental materials directly onto vital pulp tissues after deep caries removal to stimulate the regeneration of reparative dentin. This physical barrier will serve as a "biological seal" between these materials and the pulp tissue. Although numerous direct pulp capping materials are available, the use of small bioactive compounds that can potently stimulate and expedite reparative dentin formation is still underexplored. Here, the authors compared and evaluated the pro-osteogenic and pro-odontogenic effects of 4 small bioactive compounds- phenamil (Phen), purmorphamine (Pur), genistein (Gen), and metformin (Met)...
January 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28027822/semaphorin-4d-enhances-angiogenic-potential-and-suppresses-osteo-odontogenic-differentiation-of-human-dental-pulp-stem-cells
#15
Ting Zou, Waruna Lakmal Dissanayaka, Shan Jiang, Shuai Wang, Boon Chin Heng, Xiaojing Huang, Chengfei Zhang
INTRODUCTION: To investigate the roles of semaphorin 4D (Sema4D)/plexin-B1 signaling on the angiogenic potential and osteo-/odontogenic differentiation of human dental pulp stem cells (DPSCs) and to uncover the corresponding molecular mechanisms. METHODS: DPSCs were treated with Sema4D (10 μg/mL) for different time durations. Osteo-/odontogenic differentiation was assessed by quantifying alkaline phosphatase activity, mineralized nodule formation, and osteo-/odontogenic gene (ALP, Col1A1, BSP, RUNX2, and DSPP) and protein (Col1A1 and DSPP) expression...
December 24, 2016: Journal of Endodontics
https://www.readbyqxmd.com/read/28025437/diverse-calcification-patterns-of-ameloblastic-fibro-odontoma-on-radiographic-examination
#16
Masao Araki, Shunsuke Namaki, Toshihiko Amemiya, Kunihito Matsumoto, Kazuya Honda, Yoshiyuki Yonehara, Naoyuki Matsumoto, Masatake Asano
The occurrence of ameloblastic fibro-odontoma (AFO) in the oral region is unusual and accounts for 1-3% of all odontogenic tumors. AFO presents mixed radiopaque patterns within the lesion with diverse findings; therefore, it is important to compare this tumor with other odontogenic tumors that radiographically present with calcified bodies. Herein, we observed the calcification patterns within the lesion in seven AFO cases (five males, two females; mean age, 8.3 years; age range, 4-13 years). Periapical and panoramic radiographs were obtained from all seven cases...
2016: Journal of Oral Science
https://www.readbyqxmd.com/read/28025428/expression-of-p73-and-trail-in-odontogenic-cysts-and-tumors
#17
Marco Mascitti, Andrea Santarelli, Antonio Zizzi, Maurizio Procaccini, Lorenzo Lo Muzio, Corrado Rubini
Odontogenic tumors are a group of lesions arising from the odontogenic apparatus. Although the mechanism of oncogenesis and tumor progression in these lesions remains unknown, certain proteins, such as those involved in apoptosis, seem to be involved in the differentiation and proliferation of odontogenic epithelial cells. The aim of this study was to analyze the expression of p73 and TNF-related apoptosis-inducing ligand (TRAIL) in odontogenic tumors and cysts, and to clarify changes in the expression of these proteins...
2016: Journal of Oral Science
https://www.readbyqxmd.com/read/28011178/recurrence-probability-for-keratocystic-odontogenic-tumors-an-analysis-of-6427-cases
#18
Bruno Ramos Chrcanovic, Ricardo Santiago Gomez
PURPOSE: To investigate and compare the probability of recurrence of keratocystic odontogenic tumors (KCOTs) for different variables and treatment protocols. MATERIALS AND METHODS: An electronic search was undertaken in April 2016 that included clinical series of KCOTs reporting recurrences. Untransformed proportions and meta-analyses were performed to estimate the probability/risk of recurrence, according to several variables. RESULTS: A total of 94 publications were included (6427 KCOTs, 1464 recurrences)...
November 19, 2016: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28007509/keratoameloblastoma-of-the-mandible
#19
S Anajar, A Lakhbal, R Abada, M Mahtar
INTRODUCTION: Keratoameloblastoma is an extremely rare odontogenic tumor, as only 18 cases have been reported in the literature. CASE REPORT: The authors report a case of keratoameloblastoma in a 32-year-old woman and review the literature concerning the clinical features, radiological appearance, histopathological findings and treatment options. DISCUSSION: Keratoameloblastoma is a rare tumor observed more frequently in males (sex ratio: 3:1) characterized by extensive keratin production in odontogenic islets and fibrous stroma...
December 19, 2016: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/28005295/antibiotics-in-endodontics-a-review
#20
REVIEW
J J Segura-Egea, K Gould, B Hakan Şen, P Jonasson, E Cotti, A Mazzoni, H Sunay, L Tjäderhane, P M H Dummer
The overuse of antibiotics and the emergence of antibiotic-resistant bacterial strains is a global concern. This concern is also of importance in terms of the oral microbiota and the use of antibiotics to deal with oral and dental infections. The aim of this paper is to review the current literature on the indications and use of antibiotics and to make recommendations for their prescription in endodontic patients. Odontogenic infections, including endodontic infections, are polymicrobial, and in most cases, the prescription of antibiotics is empirical...
December 22, 2016: International Endodontic Journal
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