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https://www.readbyqxmd.com/read/27902954/multi-recurrent-invasive-ameloblastoma-a-surgical-challenge
#1
Fatemah Faras, Fawaz Abo-Alhassan, Yona Israël, Barbara Hersant, Jean-Paul Meningaud
INTRODUCTION: Ameloblastomas are rare head and neck tumors, and yet the most common odontogenic neoplasms. They account for 1% and 11% of all head and neck and odontogenic tumors respectively. Embryologically, they originate from remnants of odontogenic epithelium. Their aggressive, destructive nature, as well as their anticipated high rate of recurrence, even after en bloc resection, poses a surgical predicament. PRESENTATION: We present a case of a 56 year-old Asian female with a multi-recurrent invasive ameloblastoma...
November 21, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27901202/in-vivo-performance-of-different-scaffolds-for-dental-pulp-stem-cells-induced-for-odontogenic-differentiation
#2
Cigdem Atalayin, Huseyin Tezel, Taner Dagci, Nefise Ulku Karabay Yavasoglu, Gulperi Oktem, Timur Kose
This study was designed to determine the in vivo performance of three different materials as scaffolds for dental pulp stem cells (DPSC) undergoing induced odontogenic differentiation. An odontogenic medium modified by the addition of recombinant human bone morphogenetic protein 2 was used in the experimental groups to induce differentiation. Mesenchymal stem cell medium was used in the control groups. DPSC were transplanted onto the backs of mice via three scaffolds: copolymer of L-lactide and DL-lactide (PLDL), copolymer of DL-lactide (PDL) and hydroxyapatite tricalcium phosphate (HA/TCP)...
November 28, 2016: Brazilian Oral Research
https://www.readbyqxmd.com/read/27891488/management-of-recurrent-odontogenic-myxoma-of-mandible-a-clinical-case-report
#3
Yogesh Mittal, Ankita Chugh, K George Varghese, Shailendra Dwivedi, Vidhi Goyal
Odontogenic Myxoma (OM) is a slow growing painless locally aggressive tumor seen in gnathic bones and is generally asymptomatic. OM is characterized by spindle, wedge or stellate shaped cells loosely arranged in an abundant mucoid stroma. It is found incidentally on radiographs and may vary from a unilocular radiolucency to a multilocular lesion with well-defined or diffuse margins. Treatment includes surgical management that may range from simple enucleation and curettage to surgical excision including peripheral osteotomy, segmental resection, hemimandibulectomy and maxillectomy...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27891485/ameloblastic-carcinoma-a-report-of-three-cases
#4
Sravya Kodati, Sumit Majumdar, Divya Uppala, Madhurya Namana
Malignant odontogenic tumours are rare and represent approximately 1% of all oral malignancies. Ameloblastic carcinoma is a rare odontogenic tumour, which is aggressive in nature with extensive local bone destruction that has retained the features of ameloblastic differentiation and also exhibits cytological features of malignancy. It occurs primarily in the mandible in a wide range of age groups. It may arise de-novo or in pre-existing ameloblastoma or odontogenic cyst. The purpose of this report is to present three cases of ameloblastic carcinoma with varying presentations as central and peripheral entities...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27891277/a-case-of-ameloblastic-fibroodontoma-extending-maxillary-sinus-with-erupted-tooth-is-transcanine-approach-with-alveolectomy-feasible
#5
Mustafa Aslıer, Mustafa Cenk Ecevit, Sülen Sarıoğlu, Semih Sütay
Ameloblastic fibroodontoma (AFO) is a rare entity of mixed odontogenic tumors and frequently arises from posterior portion of the maxilla or mandible in first two decades of life. Herein, a 35-year-old woman with a noncontributory medical history who presented with a progressive left maxillary toothache, left maxillary first molar tooth mobility, and swelling in the left maxillary molar area for the last 2 months was reported. Radiologically, a tumor that originated from periapical area of the second mature molar teeth of maxilla was seen and additively unerupted tooth was not detected...
2016: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/27888918/systemic-and-odontogenic-etiologies-in-chronic-rhinosinusitis
#6
REVIEW
Edward C Kuan, Jeffrey D Suh
Systemic and odontogenic etiologies of chronic rhinosinusitis, although rare, are an integral consideration in the comprehensive management of patients with sinonasal disease. Proper knowledge and timely recognition of each disease process, with referrals to appropriate consultants, will facilitate treatment, because many of these conditions require both local and systemic therapy. In some instances, medical therapy plays a pivotal role, with surgery being a supplemental treatment technique. We review the most commonly encountered systemic etiologies of chronic rhinosinusitis and odontogenic sinusitis, including clinical presentation, diagnosis, management, and treatment outcomes...
February 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/27882603/establishment-and-characterization-of-a-cell-population-derived-from-a-dentigerous-cyst
#7
Marcos A Muñiz-Lino, Mariana Rodríguez-Vázquez, Bibiana Chávez-Munguía, Josué Z Ortiz-García, Lorena González-López, Fidel C Hernández-Hernández, Carlos Licéaga-Escalera, Alejandro García-Muñoz, Mario A Rodríguez
BACKGROUND: Dentigerous cyst occurs in approximately 20% of jaw cysts, being the second major common odontogenic cyst, after radicular cyst. This oral lesion has the ability to destroy maxillary bones and could be the origin of several odontogenic tumors. However, molecules implicated in its pathogenesis as well as those involved in its neoplastic transformation remain unknown. Here, we established a cell population derived from a dentigerous cyst as an in vitro model for the study of this oral lesion...
November 24, 2016: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/27876162/predictive-factors-of-hospital-stay-in-patients-with-odontogenic-maxillofacial-infections-the-role-of-c-reactive-protein
#8
P Stathopoulos, D Igoumenakis, J Shuttleworth, W Smith, P Ameerally
To investigate whether clinical or laboratory variables on admission of patients with odontogenic infections are associated with a severe clinical course and a prolonged hospital stay, we hypothesised that specific factors such as the serum concentration of C-reactive protein (CRP) may act as predictors of the duration of stay. We designed a prospective patient-oriented study that included all those treated for maxillofacial infections of odontogenic origin in the Oral and Maxillofacial Surgery Department of Northampton General Hospital between November 2013 and December 2014...
November 18, 2016: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/27876138/adenomatoid-odontogenic-tumor-what-is-the-true-nature
#9
Arush Thakur, Jagdish Vishnu Tupkari, Tabita Joy, Amrut V Hanchate
The Adenomatoid odontogenic tumor (AOT) is one of the most controversial benign odontogenic tumor, which has been known to the pathologists for the past 100years. Since then the history, histogenesis and histopathologic designation of AOT remains a matter of debate. Some authors consider it as a true benign neoplasm while others consider it as a hamartoma and still others as an odontogenic cyst. Here we propose that the AOT should not be considered as a cyst because its true cystic nature remains questionable...
December 2016: Medical Hypotheses
https://www.readbyqxmd.com/read/27875708/does-restriction-of-public-health-care-dental-benefits-affect-the-volume-severity-or-cost-of-dental-related-hospital-visits
#10
David Salomon, R Eric Heidel, Antonia Kolokythas, Michael Miloro, Thomas Schlieve
PURPOSE: On July 1, 2012, the Illinois legislature passed the Save Medicaid Access and Resources Together (SMART) Act, which restricts adult public dental insurance coverage to emergency-only treatment. The purpose of this study was to measure the effect of this restriction on the volume, severity, and treatment costs of odontogenic infections in an urban hospital. MATERIALS AND METHODS: A retrospective cohort study of patients presenting for odontogenic pain or infection at the University of Illinois Hospital was performed...
October 29, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27873145/use-of-refrigerant-spray-of-a-propane-butane-isobutane-gas-mixture-in-the-management-of-keratocystic-odontogenic-tumors-a-preliminary-study
#11
Eduardo Luis de Souza Cruz, Ana Karla da Silva Tabosa, Aline Semblano Carreira Falcão, Talita Tartari, Lucas Machado de Menezes, Edmar Tavares da Costa, José Thiers Carneiro Júnior
PURPOSE: Keratocystic odontogenic tumor (KCOT) is an aggressive benign tumor and the management by complete enucleation followed by cryotherapy maintains the inorganic bone matrix, resulting in better repair and reduces the rates of recurrence. A refrigerant spray with a propane/butane/isobutane gas mixture has been pointed to as an alternative to liquid nitrogen, because the device is easy to handle and contain within the cavity, providing better control and lower risk of injury to the adjacent soft tissue...
November 21, 2016: Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27872325/the-molecular-circuit-regulating-tooth-development-in-crocodilians
#12
S Tsai, A Abdelhamid, M K Khan, A Elkarargy, R B Widelitz, C M Chuong, P Wu
Alligators have robust regenerative potential for tooth renewal. In contrast, extant mammals can either renew their teeth once (diphyodont dentition, as found in humans) or not at all (monophyodont dentition, present in mice). Previously, the authors used multiple mitotic labeling to map putative stem cells in alligator dental laminae, which contain quiescent odontogenic progenitors. The authors demonstrated that alligator tooth cycle initiation is related to β-catenin/Wnt pathway activity in the dental lamina bulge...
December 2016: Journal of Dental Research
https://www.readbyqxmd.com/read/27872132/cutaneous-neck-lesion-of-occult-odontogenic-origin-search-for-the-tooth
#13
Ronak Ved, Jonathan Jones, Nicholas Drage, Michael Fardy
The differential diagnosis for inflammatory neck swellings is vast. A swelling of dental origin should be considered because, while rare, they mimic more common causes of neck lumps. We report the case involving a recurrent submandibular swelling in a young female patient that was presumed to be an epidermoid cyst by her general medical practitioner. After 6 months of unsuccessful treatment in the community, an odontogenic source was identified and treated successfully following referral to a local Oral and Maxillofacial department...
November 21, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27871286/maxillary-calcifying-epithelial-odontogenic-tumor-with-sinus-and-buccal-vestibule-extension-a-case-report-and-immunohistochemical-study
#14
Cristina Munteanu, Daniel Pirici, Alex Emilian Stepan, Adrian Camen, Claudiu Margaritescu
BACKGROUND: Calcifying epithelial odontogenic tumor (CEOT) is a rare benign neoplasia, locally aggressive, that tends to invade bone and adjacent soft tissues. This case report describes the thirteenth known case of CEOT with maxillary sinus extension and the second one that also involves the buccal vestibule mucosa with peculiar histopathological and immunohistochemical data. CASE PRESENTATION: Here we report the case of a 45-year-old female with a CEOT diagnosed and treated at the Oral & Maxillofacial Surgery Department, County Clinical Emergency Hospital of Craiova, Romania...
November 21, 2016: Diagnostic Pathology
https://www.readbyqxmd.com/read/27870215/detangling-the-evolutionary-developmental-integration-of-dentate-jaws-evidence-that-a-p63-gene-network-regulates-odontogenesis-exclusive-of-mandible-morphogenesis
#15
Muhammad T Raj, Julia C Boughner
Vertebrate jaws and dentitions fit and function together, yet the genetic processes that coordinate cranial and dental morphogenesis and evolution remain poorly understood. Teeth but not jaws fail to form in the edentate p63(-/-) mouse mutant, which we used here to identify genes important to odontogenesis, but not jaw morphogenesis, and that may allow dentitions to change during development and evolution without necessarily affecting the jaw skeleton. With the working hypothesis that tooth and jaw development are autonomously controlled by discreet gene regulatory networks, using gene expression microarray assays validated by quantitative reverse-transcription PCR we contrasted expression in mandibular prominences at embryonic days (E) 10-13 of mice with normal lower jaw development but either normal (p63(+/-) , p63(+/+) ) or arrested (p63(-/-) ) tooth development...
December 2016: Evolution & Development
https://www.readbyqxmd.com/read/27865804/ghost-cell-tumors
#16
Jason Sheikh, Molly D Cohen, Naomi Ramer, Ali Payami
Ghost cell tumors are a family of lesions that range in presentation from cyst to solid neoplasm and in behavior from benign to locally aggressive or metastatic. All are characterized by the presence of ameloblastic epithelium, ghost cells, and calcifications. This report presents the cases of a 14-year-old girl with a calcifying cystic odontogenic tumor (CCOT) and a 65-year-old woman with a peripheral dentinogenic ghost cell tumor (DGCT) with dysplastic changes, a rare locally invasive tumor of odontogenic epithelium...
October 26, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27859616/immunohistochemical-expression-of-podoplanin-d2-40-lymphangiogenesis-and-neoangiogenesis-in-tooth-germ-ameloblastomas-and-ameloblastic-carcinomas
#17
Celeste Sánchez-Romero, Ronell Bologna-Molina, Adalberto Mosqueda-Taylor, Oslei Paes de Almeida
BACKGROUND: Ameloblastoma is a benign but locally aggressive odontogenic tumor, while ameloblastic carcinoma is its malignant counterpart. Angiogenesis and lymphangiogenesis in malignancies have been correlated with higher aggressiveness and poor prognosis, as well as greater expression of podoplanin by tumoral cells. METHODS: Immunohistochemical expression of podoplanin, CD34, and CD105 (endoglin) was evaluated in 53 ameloblastomas and three ameloblastic carcinomas; additionally, immunohistochemistry for podoplanin was also performed in 10 tooth germs...
November 10, 2016: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/27857903/orthokeratinized-odontogenic-cyst-masquerading-as-dentigerous-cyst
#18
Devi Charan Shetty, Ajit Singh Rathore, Anshi Jain, Natasha Thokchom, Neha Khurana
The orthokeratinized odontogenic cyst (OOC) is a rare developmental odontogenic cyst that has been considered as a variant of the keratocystic odontogenic tumor until Wright (1981) defined it as a different entity. Recognition of OOC as a unique entity has long been due, yet its inexplicable clinical, radiographic presentation resembling dentigerous cyst due to its association to an impacted tooth, and its histological features makes it rather perplexing. This is the report of a case of OOC in relation to an impacted maxillary canine and its immunohistochemical analysis with Ki-67...
October 2016: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/27857774/a-case-report-and-short-review-on-changing-trends-in-the-site-of-occurrence-of-adenomatoid-odontogenic-tumor-unravelling-the-past-15-years
#19
Sneha Sethi, Manish Kumar, Pratul Aggarwal, H S Indra Kumar, Chetan D Sugandhi, Silvie Singh
Adenomatoid odontogenic tumor (AOT) is an uncommon benign odontogenic lesion, with debatable histogenesis and variable histopathology. A systematic and diverse insight into the evolution, clinical presentation, histology, and immunohistochemical findings of this lesion is reviewed and presented. We reviewed the data published from 2000 to 2014 of approximately 255 cases that revealed a significant change in the incidence of predominant site involved, in contrast to the findings published by Reichart. We have also included the chronological order of events leading to the coining of the term AOT, which shows the curiosity that has been dedicated to understanding the lesion...
September 2016: Dental Research Journal
https://www.readbyqxmd.com/read/27857042/odontogenic-keratocysts-in-the-basal-cell-nevus-gorlin-goltz-syndrome-associated-with-paresthesia-of-the-lower-jaw-case-report-retrospective-analysis-of-a-representative-czech-cohort-and-recommendations-for-the-early-diagnosis
#20
(no author information available yet)
OBJECTIVES: Identification of early presenting signs of the Basal Cell Nevus (BCNS; synonyme Gorlin-Goltz) syndrome, which is associated with a principal triad of multiple basal cell nevi, jaw odontogenic keratocysts, and skeletal anomalies, in stomatological and neurological practices. Proposal of multidisciplinary diagnostic algorithm comprising other medical specialists, including pathology, imaging, laboratory and molecular analyses based on the study outcomes. DESIGN: Case report of a male patient reporting paresthesia of their lower jaw, with right facial asymmetry (maxilla and mandible) and radiological detection of large osteolytic lesions in both jaws, including a retrospective analysis of a representative Czech cohort with BCNS from within the last decade...
September 18, 2016: Neuro Endocrinology Letters
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