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Odontogenic

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https://www.readbyqxmd.com/read/29046381/trunk-dental-tissue-evolved-independently-from-underlying-dermal-bony-plates-but-is-associated-with-surface-bones-in-living-odontode-bearing-catfish
#1
Carlos J Rivera-Rivera, Juan I Montoya-Burgos
Although oral dental tissue is a vertebrate attribute, trunk dental tissue evolved in several extinct vertebrate lineages but is rare among living species. The question of which processes trigger dental-tissue formation in the trunk remains open, and would shed light on odontogenesis evolution. Extra-oral dental structures (odontodes) in the trunk are associated with underlying dermal bony plates, leading us to ask whether the formation of trunk bony plates is necessary for trunk odontodes to emerge. To address this question, we focus on Loricarioidei: an extant, highly diverse group of catfish whose species all have odontodes...
October 25, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/29039452/molecular-analysis-of-keratocystic-odontogenic-tumor-cell-lines-derived-from-sporadic-and-basal-cell-nevus-syndrome-patients
#2
Kazuma Noguchi, Keiko Wakai, Tohru Kiyono, Mutsuki Kawabe, Kyohei Yoshikawa, Tomoko Hashimoto-Tamaoki, Hiromitsu Kishimoto, Yoshiro Nakano
Keratocystic odontogenic tumor (KCOT) is a benign tumor often associated with basal cell nevus syndrome (BCNS). Mutations in Patched 1 (PTCH1), the Hedgehog (Hh) receptor, are responsible for BCNS. BCNS is distinguished by morphological anomalies and predisposition to benign and malignant tumors, including medulloblastoma, basal cell carcinoma, KCOT and ovarian fibromas. Among these tumors, KCOT is the least well studied because a suitable model system is not available for its investigation. To enable KCOT to be studied, we established two KCOT cell lines, one from a BCNS case (designated as iKCOT1) and one from a sporadic KCOT case (designated as sKCOT1)...
October 9, 2017: International Journal of Oncology
https://www.readbyqxmd.com/read/29038627/characterization-and-antibiotic-sensitivity-profile-of-bacteria-in-orofacial-abscesses-of-odontogenic-origin
#3
H Jagadish Chandra, B H Sripathi Rao, A P Muhammed Manzoor, A B Arun
BACKGROUND: Odontogenic infections range from peripheral abscess to superficial and deep infections leading to severe infections in head and neck region. This study was aimed to assess bacterial isolates responsible for orofacial infection of odontogenic origin and their drug susceptibility patterns so as to provide better perceptive for the management of odontogenic infections. METHODS: The study was made in a selected cohort of patients, irrespective of age and gender having moderate and severe orofacial infections of odontogenic origin admitted to Yenepoya University Hospital...
December 2017: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/29034280/ameloblastic-fibro-odontoma-in-a-7-month-old-infant-a-case-report
#4
Fatemeh Mashhadiabba, Nafiseh Shamloo, Mehdi Jafari, Shahla Vafadar
Ameloblastic fibro-odontoma is a relatively rare, benign odontogenic tumor that usually occurs in children and adolescents with unerupted teeth. This article reports an ameloblastic fibro-odontoma in the anterior mandible as a "bump on her gum" in a 7-month-old girl. This is the first case under 9 months old reported to date. Radiographic and histologic findings as well as the treatment are discussed.
September 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/29032608/microrna-profiling-reveals-dysregulated-micrornas-and-their-target-gene-regulatory-networks-in-cemento-ossifying-fibroma
#5
Thaís Dos Santos Fontes Pereira, João Artur Ricieri Brito, André Luiz Sena Guimarães, Carolina Cavaliéri Gomes, Júlio Cesar Tanos de Lacerda, Wagner Henriques de Castro, Roney Santos Coimbra, Marina Gonçalves Diniz, Ricardo Santiago Gomez
BACKGROUND: Cemento-ossifying fibroma (COF) is a benign fibro-osseous neoplasm of uncertain pathogenesis and its treatment results morbidity. MicroRNAs (miRNA) are small non-coding RNAs that regulate gene expression and may represent therapeutic targets. The purpose of the study was to generate a comprehensive miRNA profile of COF compared to normal bone. Additionally, the most relevant pathways and target genes of differentially expressed miRNA were investigated by in silico analysis...
October 15, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/29027917/porcine-dental-epithelial-cells-differentiated-in-a-cell-sheet-constructed-by-magnetic-nanotechnology
#6
Wataru Koto, Yoshinori Shinohara, Kazuyuki Kitamura, Takanori Wachi, Seicho Makihira, Kiyoshi Koyano
Magnetic nanoparticles (MNPs) are widely used in medical examinations, treatments, and basic research, including magnetic resonance imaging, drug delivery systems, and tissue engineering. In this study, MNPs with magnetic force were applied to tissue engineering for dental enamel regeneration. The internalization of MNPs into the odontogenic cells was observed by transmission electron microscopy. A combined cell sheet consisting of dental epithelial cells (DECs) and dental mesenchymal cells (DMCs) (CC sheet) was constructed using magnetic force-based tissue engineering technology...
October 13, 2017: Nanomaterials
https://www.readbyqxmd.com/read/29018483/the-angiogenic-potential-of-dpscs-and-scaps-in-an-in-vivo-model-of-dental-pulp-regeneration
#7
Petra Hilkens, Annelies Bronckaers, Jessica Ratajczak, Pascal Gervois, Esther Wolfs, Ivo Lambrichts
Adequate vascularization, a restricting factor for the survival of engineered tissues, is often promoted by the addition of stem cells or the appropriate angiogenic growth factors. In this study, human dental pulp stem cells (DPSCs) and stem cells from the apical papilla (SCAPs) were applied in an in vivo model of dental pulp regeneration in order to compare their regenerative potential and confirm their previously demonstrated paracrine angiogenic properties. 3D-printed hydroxyapatite scaffolds containing DPSCs and/or SCAPs were subcutaneously transplanted into immunocompromised mice...
2017: Stem Cells International
https://www.readbyqxmd.com/read/29017682/calcifying-cystic-odontogenic-tumor
#8
Muhammad Zeeshan Baig, Haafsa Arshad Sahibzada, Khalid Mahmood Siddiqi
No abstract text is available yet for this article.
September 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28986711/blockade-of-lgr4-inhibits-proliferation-and-odonto-osteogenic-differentiation-of-stem-cells-from-apical-papillae
#9
Meng Zhou, Shuyu Guo, Lichan Yuan, Yuxin Zhang, Mengnan Zhang, Huimin Chen, Mengting Lu, Jianrong Yang, Junqing Ma
During tooth root development, stem cells from apical papillae (SCAPs) are indispensable, and their abilities of proliferation, migration and odontoblast differentiation are linked to root formation. Leucine-rich repeat-containing GPCR 4 (LGR4) modulates the biological processes of proliferation and differentiation in multiple stem cells. In this study, we showed that LGR4 is expressed in all odontoblast cell lineage cells and Hertwig's epithelial root sheath (HERS) during the mouse root formation in vivo. In vitro we determined that LGR4 is involved in the Wnt/β-catenin signaling pathway regulating proliferation and odonto/osteogenic differentiation of SCAPs...
October 6, 2017: Journal of Molecular Histology
https://www.readbyqxmd.com/read/28986386/bacterial-isolates-and-antimicrobial-susceptibilities-from-odontogenic-abscesses-in-rabbits-48-cases
#10
Sara Gardhouse, David Sanchez-Migallon Guzman, Joanne Paul-Murphy, Barbara A Byrne, Michelle G Hawkins
The medical record database of a veterinary teaching hospital was searched from 2000 through 2014 for records of client-owned rabbits with positive cultures from odontogenic abscesses. Data reviewed included sex, age, abscess location, sampling technique, previous antimicrobial treatments, microorganisms identified and antibiotic susceptibility of aerobic bacteria. Forty-eight client owned rabbits with one or more odontogenic abscesses and culture results were evaluated. One hundred and eighty-five isolates (52 aerobic, 133 anaerobic) were identified from 61 positive cultures from odontogenic abscesses...
October 6, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28985009/odontogenic-myxoma-a-63-year-retrospective-multicenter-study-of-85-cases-in-a-brazil-population-and-a-review-of-999-cases-from-literature
#11
Ana Carolina Uchoa Vasconcelos, Felipe Martins Silveira, Ana Paula Neutzling Gomes, Sandra Beatriz Chaves Tarquinio, Ana Paula Veras Sobral, José Alcides Almeida de Arruda, Leorik Pereira da Silva, Marcia Maria Fonseca da Silveira, Larissa Ferreira Barbosa, Camila de Nazaré Alves de Oliveira Kato, Filipe Jaeger, Tarcília Aparecida da Silva, Ricardo Alves Mesquita
BACKGROUND: Odontogenic myxoma (OM) is an uncommon neoplasm of the jaws. Considering the importance of defining the relative incidence and demographic profile of these lesions in South America, the aim of this study was to analyze the clinical and imagiological features of OM from three South American oral pathology services and to discuss these findings in light of the literature. METHODS: Data regarding age, gender, anatomic site and imagiological features from 85 cases of OM were collected...
October 6, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/28984343/the-world-health-organization-classification-of-odontogenic-lesions-a-summary-of-the-changes-of-the-2017-4th-edition
#12
Merva Soluk-Tekkeşin, John M Wright
The 4 < sup > th < /sup > edition of the World Health Organization (WHO) Classification of Head and Neck Tumors was published in January 2017. The edition serves to provide an updated classification scheme, and extended genetic and molecular data that are useful as diagnostic tools for the lesions of the head and neck region. This review focuses on the most current update of odontogenic cysts and tumors based on the 2017 WHO edition. The updated classification has some important differences from the 3 < sup > rd < /sup > edition (2005), including a new classification of odontogenic cysts, 'reclassified' odontogenic tumors, and some new entities...
October 6, 2017: Türk Patoloji Dergisi
https://www.readbyqxmd.com/read/28981207/medication-related-osteonecrosis-of-the-posterior-maxilla-surgical-treatment-using-a-combined-transnasal-endoscopic-and-intraoral-approach-our-experience-with-seven-consecutive-patients
#13
Pasquale Procacci, Massimo Albanese, Lorenzo Trevisiol, Vittorio Favero, Dario Bertossi, Fabio Lonardi, Antonio D'Agostino, Erminia Manfrin, Pier Francesco Nocini
Upper jaw MRONJ if not correctly treated can lead to serious complication. Upper jaw MRONJ is frequently associated with maxillary sinusitis, the disease can spread to other paranasal sinuses. Combined approach is the most reliable procedure to treat odontogenic sinusitis; although MRONJ associated sinusitis is considered odontogenic there is no report in literature describing combined approach to treat MRONJ-induced sinusitis. Buccal fat pad represents the best reconstructive option to close the bony defect...
October 5, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28980600/-the-radicular-cyst-in-the-maxillary-sinus-encountered-in-the-clinical-otorhinolaryngological-practice
#14
A B Turovsky, I G Kolbanova, G V Kuznetsov, Yu S Kudryavtseva
This article was designed to report the clinical case of the radicular cyst localized in the maxillary sinus of the 23 year-old man that had been detected before the surgical intervention was undertaken for its treatment. In the preceding visits of the patient to other medical settings, this condition was misinterpreted as a genuine (rhinogenic) cyst. It accounted for the choice of the inadequate surgical strategy for the management of this pathology. As a result, the patient experienced two relapse episodes of the disease...
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/28978274/a-case-of-congenital-supernumerary-teeth-in-an-ovine-dental-pad
#15
Juan Alberto Corbera, Immaculada Morales, Sergio Martin, Alberto Arencibia, Carlos Gutierrez
A rare case of congenital supernumerary teeth, also known as hyperdontia, observed in a healthy 8-month-old female ewe is presented. The congenital defect consisted of the presence of 2 incisor teeth embedded in the lateral areas of the dental pad. The anomaly was found during a routine physical examination and no other congenital abnormalities were found in the patient. No prior congenital abnormalities had been seen in the herd and the study of possible associated teratogenic factors was inconclusive. To the authors' knowledge, this ovine odontogenic abnormality has not been described in the literature and appears to be an extraordinarily rare condition...
January 1, 2017: Journal of Veterinary Dentistry
https://www.readbyqxmd.com/read/28978273/clinical-characterization-of-canine-acanthomatous-ameloblastoma-caa-in-263-dogs-and-the-influence-of-postsurgical-histopathological-margin-on-local-recurrence
#16
Stephanie L Goldschmidt, Cindy M Bell, Scott Hetzel, Jason Soukup
Canine acanthomatous ameloblastoma (CAA) has been reported to be the most common odontogenic tumor in dogs. This retrospective study evaluated 263 dogs with histopathologically confirmed CAA. Within this data set, CAA presents most commonly in the rostral mandible in adult large breed dogs, with golden retriever dogs being overrepresented. Patients with appropriate follow-up after curative intent surgery were evaluated to assess the effect of histopathological margin on local tumor recurrence. No local recurrence was noted in any patient...
January 1, 2017: Journal of Veterinary Dentistry
https://www.readbyqxmd.com/read/28976118/peripheral-odontogenic-fibroma-a-rare-gingival-neoplasm-with-clinico-pathological-differential-diagnosis
#17
Rajesh Kumar, Shradha Jaiswal, Aanchal Sharma, Vinod Andhare, Husain Sabir
The peripheral odontogenic fibroma (POdF) is a rare gingival neoplasm, characterised by relatively mature collagenous fibrous tissue and varying amounts of odontogenic epithelium. It can be described as a slow growing, firmly attached, solid and smooth gingival mass which may be present asymptomatically for years, which may cause displacement of adjacent teeth. The purpose of this article is to discuss a case of POdF, occurring in the maxillary anterior region, with detailed clinico-pathological differential diagnosis to clarify characteristic features of various gingival overgrowths to enhance easy identification...
September 2017: Journal of Experimental Therapeutics & Oncology
https://www.readbyqxmd.com/read/28969743/ortho-keratinized-odontogenic-cyst-with-dentinoid-formation
#18
Manas Bajpai, Nilesh Pardhe, Manika Aroroa, Betina Chandolia
Orthokeratinized odontogenic keratocyst (OOC) was first identified as orthokeratinized variant of odontogenic keratocyst in 1981 by Wright, due to its different histology and relatively low recurrence rate. Parakeratinized odontogenic cyst is now considered as keratocystic odontogenic tumor (KCOT) owing to its neoplastic nature. Although rare, calcification in the form of dystrophic calcification, dentinoid and cartilage has been reported in KCOT, but calcification in OOC is extremely rare and no case in English literature has been reported so far...
September 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28969297/pleomorphic-adenoma-masquerading-as-odontogenic-lesion-in-the-maxilla
#19
Lavanya Mallika, Dominic Augustine, Parimala Sagar, Kavitha Prasad, Roopa S Rao
No abstract text is available yet for this article.
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28969291/ghost-cell-odontogenic-carcinoma-arising-denovo-with-distant-metastasis-a-case-report-and-review-of-literature
#20
Madhurya Namana, Sumit Majumdar, Divya Uppala, Aditya Avv, Ayyagari Kameswara Rao
Ghost Cell Odontogenic Carcinoma (GCOC) is a rare malignant odontogenic tumour of epithelial origin accounting about 0.37% to 2.1% of all odontogenic tumours. They are characterized by the presence of ameloblastic islands along with ghost cells representing aberrant keratinization. The aim of this case report is to present a rare case that was diagnosed in a 37-year-old male patient and to describe the behavior of the tumour.
August 2017: Journal of Clinical and Diagnostic Research: JCDR
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