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https://www.readbyqxmd.com/read/29676382/peripheral-variant-of-calcifying-epithelial-odontogenic-tumor-with-clear-cell-changes-an-enigma
#1
Manas Bajpai
No abstract text is available yet for this article.
April 2018: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/29676366/pindborg-tumor-pathology-with-special-stains
#2
Swati Shrikant Gotmare, Treville Pereira, Subraj Shetty, Kashmira S Kesarkar
Odontogenic tumors constitute a wide spectrum of lesions ranging from malignant and benign neoplasms to dental hamartomas, all derived from the epithelial and ectomesenchymal remnants of the tooth forming apparatus. Calcifying epithelial odontogenic tumor (CEOT) is an uncommon, benign epithelial odontogenic tumor first described by Pindborg in 1956. It is a universally accepted eponym for this neoplasm. Pindborg tumor or CEOT is a locally aggressive neoplasm that accounts for 1% of the total odontogenic tumors, with recurrence in 14% of cases...
April 2018: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/29673728/infrahyoid-involvement-may-be-a-high-risk-factor-in-the-management-of-non-odontogenic-deep-neck-infection-retrospective-study
#3
Hui Yuan, Rong Gao
OBJECTIVES: This study sought to investigate the impact of involvement of the infrahyoid neck space on the management of non-odontogenic DNI. METHOD: Eighty-one patients treated for non-odontogenic DNI over 5 years were retrospectively recruited into this study. Demographics, etiology, radiology results, treatments, duration/cost of hospital stay, and complications were recorded. Differences between DNIs with and without infrahyoid involvement, as defined based on an anatomical chart, were analyzed...
March 16, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29672163/an-unusual-case-of-an-odontogenic-keratocyst-associated-with-an-ungrafted-alveolar-cleft-a-case-report-and-review-of-the-literature
#4
Sapna Radia, Alexander C Cash, Kanwalraj Moar
We describe an unusual case of an odontogenic keratocyst (OKC) associated with an ungrafted left-sided alveolar cleft in a 10-year-old male patient. There is no previous report in the literature of OKC or other dental cysts associated with an alveolar cleft. We discuss the management of the OKC prior to secondary bone grafting and present this case to highlight the difficulty in the management of OKC concurrent with grafting of the alveolar cleft site, the proximity of unerupted permanent teeth, and possible treatment modalities...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29665753/apical-elongation-of-molar-teeth-in-captive-microtus-voles
#5
Denise M Imai, Risa Pesapane, Christopher J Conroy, Christina N Alarcón, Nora Allan, Russell A Okino, Jennifer Fung, Brian G Murphy, Frank J M Verstraete, Janet E Foley
Molar apical elongation (MAE) was the leading cause for euthanasia or death in a captive breeding colony of endangered Amargosa voles ( Microtus californicus scirpensis). Clinical signs included ocular discharge, abnormal mastication, dyspnea, abnormal mentation, weight loss, and death. Although the severity varied, all molars in all quadrants were affected. When severe, the overgrown molar reserve crown and apex protruded into the nasal meatuses, the orbit, the calvarial vault and through the ventral margin of the mandible...
January 1, 2018: Veterinary Pathology
https://www.readbyqxmd.com/read/29663916/a-bag-of-marbles-a-fascinating-compound-odontoma-of-the-maxilla
#6
Aneesh Kalra, Evelyn C Sheehy, Joanna Johnson, Fraser McDonald
Odontomas are the most common odontogenic tumors, typically diagnosed during the first two decades of life. 1 The purpose of this paper was to report an interesting case of an eight-year-old Caucasian boy who presented with an asymptomatic, progressive, firm swelling of the right maxilla with no eruption of the permanent maxillary right lateral incisor. Radiographic investigation revealed a mixed radiolucent and radiopaque lesion measuring 28 by 24 by 17 mm with a corticated border causing expansion and thinning of the buccal cortical plate...
March 15, 2018: Pediatric Dentistry
https://www.readbyqxmd.com/read/29663114/impact-of-odontogenic-chronic-rhinosinusitis-on-general-health-related-quality-of-life
#7
Robert A Gaudin, Lloyd P Hoehle, Ralf Smeets, Max Heiland, David S Caradonna, Stacey T Gray, Ahmad R Sedaghat
Chronic rhinosinusitis (CRS) may arise due to odontogenic etiologies. However, it is unknown whether odontogenic CRS has a differential impact on patients' quality of life (QOL) compared to standard, inflammatory (but non-odontogenic) CRS. The objective of this study was to determine whether there is a difference in the impact of sinonasal symptomatology on general health-related QOL in odontogenic CRS compared to non-odontogenic CRS. This was a retrospective review of 21 odontogenic CRS patients who visited our tertiary care center...
April 17, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29657523/comparison-of-osteoclastogenesis-and-local-invasiveness-of-ameloblastoma-and-keratocystic-odontogenic-tumor
#8
Natheer H Al-Rawi, Ammar K Al-Siraj, Ahlam H Majeed
Objectives: The aim of this study was to compare the expression of receptor-activated nuclear factor kappa B (RANK) with its ligand (RANKL) and matrix metalloproteinase-2 (MMP2) in solid/multicystic ameloblastomas (ABs) and keratocystic odontogenic tumors (KOTs). Materials and Methods: The expression of MMP2, RANK, and RANKL molecules was evaluated in 13 ABs and 14 KOTs by immunohistochemistry. The expressions were calculated in the odontogenic epithelial cells as well as the stromal cells...
January 2018: European Journal of Dentistry
https://www.readbyqxmd.com/read/29657251/laminin-1-acts-as-an-adhesive-for-odontoblast-like-cells-and-promotes-their-differentiation-toward-a-hard-tissue-forming-phenotype
#9
Jia Tang, Takashi Saito
The present study was designed to investigate the effect of laminin-1 (LN-1 or LN-111) on an odontoblast-like cell line, MDPC-23. Wells of non-treated polystyrene plates were coated with various concentrations of LN-1 (0.1, 1, 10, and 100 µg/mL) and left to dry for 2 days. Water-coated surfaces were used as controls. MDPC-23 cell proliferation, differentiation and mineralization were evaluated in terms of the CCK-8 assay, ALP activity, real-time RT-PCR and Alizarin red staining. The data indicated that LN-1 promoted the proliferation of MDPC-23 cells in a concentration-dependent manner...
April 16, 2018: Journal of Oral Science
https://www.readbyqxmd.com/read/29655415/clinicopathological-analysis-of-232-radicular-cysts-of-the-jawbone-in-a-population-of-southern-taiwanese-patients
#10
Jeng-Huey Chen, Chih-Huang Tseng, Wen-Chen Wang, Ching-Yi Chen, Fu-Hsiung Chuang, Yuk-Kwan Chen
This retrospective study aimed to evaluate the clinicopathological features of 232 cases of radicular cyst (January 2001-December 2016) submitted for histopathological examination to Department of Oral Pathology by endodontists in our institution. Demographic data including age, gender, affected site, involved tooth, and histopathological features, were reviewed. The study population comprised 133 females (57.3%) and 99 males (42.7%), with a mean age of 40.5 years and an age range of 13-78 years. Two-hundred and one cysts occurred in the maxilla (86...
April 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/29652021/an-unusual-presentation-of-ghost-cell-odontogenic-carcinoma-a-case-report-with-review-of-literature
#11
K Remya, S Sudha, Reshmi G Nair, H Jyothi
Ghost cell odontogenic carcinoma (GCOC) is a malignant odontogenic epithelial tumor which is an exceedingly rare, highly aggressive, rapidly growing, and infiltrative tumor forming the malignant counterpart of long-standing benign cystic lesions coming in the spectrum of calcifying odontogenic cysts. To date, only a few cases have been reported in the medical literature. A case of unusual presentation of GCOC is presented and the clinical, histopathological, and immunohistochemical features are discussed along with a literature review...
March 2018: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/29650947/hsa-let-7c-controls-the-committed-differentiation-of-igf-1-treated-mesenchymal-stem-cells-derived-from-dental-pulps-by-targeting-igf-1r-via-the-mapk-pathways
#12
Gen-Xia Liu, Shu Ma, Yao Li, Yan Yu, Yi-Xiang Zhou, Ya-Die Lu, Lin Jin, Zi-Lu Wang, Jin-Hua Yu
The putative tumor suppressor microRNA let-7c is extensively associated with the biological properties of cancer cells. However, the potential involvement of let-7c in the differentiation of mesenchymal stem cells has not been fully explored. In this study, we investigated the influence of hsa-let-7c (let-7c) on the proliferation and differentiation of human dental pulp-derived mesenchymal stem cells (DPMSCs) treated with insulin-like growth factor 1 (IGF-1) via flow cytometry, CCK-8 assays, alizarin red staining, real-time RT-PCR, and western blotting...
April 13, 2018: Experimental & Molecular Medicine
https://www.readbyqxmd.com/read/29644561/osteoprotegerin-deficiency-causes-morphological-and-quantitative-damage-in-epithelial-rests-of-malassez
#13
Yunfei Wang, Mengmeng Liu, Shijian Deng, Xin Sui, Linlin Fan, Qi Zhang
Epithelial rests of Malassez (ERM), the only odontogenic epithelial structures in periodontal tissue, are proposed to correlate with root resorption, but the detailed mechanism remains unclear. Osteoprotegerin (OPG), the main inhibitor of osteoclastogenesis, plays a pivotal role in inhibiting root resorption, and ERM cells express OPG mRNA in vitro. Thus, in this study, we aimed to clarify OPG expression in ERM in vivo and to explore the role of OPG in ERM to determine whether ERM are associated with root resorption via OPG...
April 11, 2018: Journal of Molecular Histology
https://www.readbyqxmd.com/read/29629885/jaw-bones-regeneration-using-mesenchymal-stem-cells-a-single-center-experience
#14
Walter Colangeli, Umberto Riccelli, Amerigo Giudice, Ida Barca, Davide Caruso, Daniela Novembre, Claudio Tortosa, Raffaella Cordaro, Maria Giulia Cristofaro
PURPOSE: Mesenchymal stem cells (MSC), which are multipotent stromal cells, are considered to be a promising resource in tissue engineering and tissue regeneration. MSCs have been used to generate new maxillary bone with clinically successful results. The aim of this study was to determine the role of MSC in bone regeneration procedures in patients with benign maxillary lesions. METHODS: A study was conducted on five patients treated for maxillary bone defects resulting from biopsy of benign lesions at the University Hospital of Magna Græcia, Catanzaro, Italy from January 2015 to October 2016...
2018: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/29623214/mandibular-osteomyelitis-due-to-raoultella-species
#15
Philip W Lam, Manal Tadros, Ignatius W Fong
Introduction: Raoultella is a genus of aerobic Gram-negative bacilli belonging to the family Enterobacteriaceae that are commonly found in water, soil and aquatic environments. With improved bacterial identification techniques, Raoultella species (namely R. planticola and R. ornithinolytica ) have been an increasingly reported cause of infections in humans. Case presentation: An 85-year-old man presented to hospital with a several-week history of left jaw pain and trismus...
March 2018: JMM Case Reports
https://www.readbyqxmd.com/read/29621081/odontogenic-keratocysts-as-first-manifestation-of-nevoid-basal-cell-carcinoma-syndrome-surgical-management-and-immunohistochemical-analysis
#16
Jessica Luana Dos Santos, Renata Zoraida Rizental Delgado, Greison Rabelo de Oliveira, Ana Lúcia Carrinho Ayroza Rangel
Nevoid Basal Cell Carcinoma Syndrome (NBCCS), also known as Gorlin syndrome, is a rare autosomal dominant disorder, with no gender predilection. Individuals with NBCCS are commonly diagnosed between 17 and 35 years old and can present multiple basal cell carcinomas scattered throughout the body, presence of recurrent and early-onset odontogenic keratocysts (OKCs) and skeletal abnormalities. This article describes a case of a 13-year-old white boy who referred complaining of facial asymmetry. Extraoral examination revealed volumetric increase displacing the nasal ala from the right side and extended to the zygomatic bone...
April 4, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29620170/increased-level-of-cell-derived-microparticles-in-the-cyst-fluids-of-odontogenic-keratocysts
#17
Qi-Wen Man, Wen-Qun Zhong, Jian-Gang Ren, Jin-Yuan Liu, Yue-Yu Zheng, Rui-Fang Li, B Fidele Nyimi, Gang Chen, Yi-Fang Zhao, Bing Liu
The aim of this study was to examine the level and basic characteristics of cell‑derived microparticles (MPs) in the cyst fluids of odontogenic keratocysts (OKCs). For this purpose, MPs from the cyst fluids (CFMPs) of OKCs were purified by a classic differential centrifugation method and characterized by a transmission electron microscope and fluorescence microscope. Flow cytometric analysis was used to determine the size, concentration and cellular origins of the CFMPs. Moreover, the expression level of receptor activator for nuclear factor‑κB ligand in the OKCs was evaluated by immunohistochemical staining and then analyzed for its correlation with the concentration of CFMPs by Spearman's rank correlation test...
April 5, 2018: International Journal of Oncology
https://www.readbyqxmd.com/read/29609668/radiopacities-of-the-jaws-interpretation-and-diagnosis
#18
David Andrew
General dental practitioners are less confident at diagnosing radiopaque lesions of the jaws than radiolucent ones, possibly because the incidence of jaw radiopacities is comparatively low. The current review covers the majority of radiopaque lesions that are referred for a specialist opinion, and focuses on those lesions that occur commonly or those that mimic other diagnoses. The majority of radiopaque jaw lesions represent normal anatomy/normal variants or superimposed soft tissue calcifications that are typically of no clinical significance...
March 1, 2018: Primary Dental Journal
https://www.readbyqxmd.com/read/29607833/assessing-clinical-sequelae-of-untreated-caries-among-5-12-and-15-year-old-school-children-in-ambala-district-a-cross-sectional-study
#19
Jasneet Sudan, Girish Malleshappa Sogi, L Koretigire Veeresha
Background: Dental caries is a public health problem globally, especially in children. Thus, it is important to quantify its clinical consequences in terms of its prevalence and severity. Aim: This study aims to assess the prevalence and severity of oral conditions linked with untreated dental caries using pulp involvement, ulceration, fistula, abscess (pufa/PUFA) index in 5-, 12-, and 15-year-old school children in Ambala district. Settings and Design: This cross-sectional study was conducted among 433 school children of 5-, 12-, and 15-year-old age group in Ambala district...
January 2018: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/29604248/mir-675-promotes-odontogenic-differentiation-of-human-dental-pulp-cells-by-epigenetic-regulation-of-dlx3
#20
Li Zeng, Na Zhao, Fang Li, Dong Han, Yang Liu, Haochen Liu, Shichen Sun, Yixiang Wang, Hailan Feng
In a previous study, we showed that microRNA-675 (miR-675) was significantly down-regulated in pateints with tricho-dento-osseous (TDO) syndrome. One of the main features of TDO syndrome is dentin hypoplasia. Thus, we hypothesize that miR-675 plays a role in dentin development. In this study, we determined the role of miR-675 in the odontogenic differentiation of human dental pulp cells (hDPCs). Stable overexpression and knockdown of miR-675 in hDPCs were performed using recombinant lentiviruses containing U6 promoter-driven miR-675 and short hairpin-miR675 expression cassettes, respectively...
March 28, 2018: Experimental Cell Research
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