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https://www.readbyqxmd.com/read/29786576/the-histological-and-electron-microscopic-study-of-the-parotid-salivary-gland-in-dehydrated-rats-of-different-ages
#1
Denys P Biletskyy, Oleg A Ustiansky, Olena S Maksymova, Pavel A Moskalenko, Alexey A Tymoshenko, Anna S Degtyarenko, Viktoriia Yu Harbuzova, Yevhen I Dubovyk, Andrii P Voznyi, Gennadii F Tkach
OBJECTIVE: Introduction: Water-salt metabolism disorders is one of the main factor of salivary gland pathology development. The aim: To study the morphological structure of the parotid salivary gland of young, mature and old rats at micro- and ultrastructural levels under water deprivation. PATIENTS AND METHODS: Materials and methods: The experiment was carried out on thirty six laboratory male rats of different ages (young, mature and old). The rats of the control group received normal volume of drinking water...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29786575/spatial-organization-of-the-excretory-ducts-and-sections-of-microcirculatory-blood-flow-of-the-labial-salivary-glands-in-older-adults
#2
Volodymyr H Hryn, Tamara F Deineha, Аndrij V Piliuhin, Anna V Lavrenko, Dmytro O Lavrenko
OBJECTIVE: Introduction: Salivary glands have a significant impact on the state of the homeostasis of the human body, oral cavity in particular, sensitively responding to pathological processes. The reactivity of the salivary glands in response to pathological processes that are organically linked to morphology and functions of the organ's structures, and particularly the excretory ducts of the glands and their microcirculatory blood flow, is one of the problems which have not been solved to date...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29785687/education-is-associated-with-the-magnitude-of-cortisol-responses-to-psychosocial-stress-in-college-students
#3
Andrew W Manigault, Alex Woody, Peggy M Zoccola, Sally S Dickerson
PURPOSE: Researchers benefit from controlling for individual differences that systematically account for variance in acute cortisol responses (e.g., sex). Similarly, some suggest that education could be used as a cortisol covariate because prior work found a negative relationship between education and the magnitude of acute cortisol responses in middle-aged adults. Nevertheless, education is seldom controlled for in tests of cortisol responses to acute stress, in part because the effect of education on acute cortisol responses has yet to be tested in a college sample...
May 21, 2018: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/29785628/gut-associated-bacteria-of-helicoverpa-zea-indirectly-trigger-plant-defenses-in-maize
#4
Jie Wang, Mingyu Yang, Yuanyuan Song, Flor E Acevedo, Kelli Hoover, Rensen Zeng, Gary W Felton
Insect-associated microbes can contribute to the physiological and ecological functions of insects. Despite a few examples in beetles and piercing-sucking insects, the varied mechanisms of how insect-associated bacteria mediate plant-insect interactions are still not fully understood. The polyphagous herbivore Helicoverpa zea is a major agricultural pest that harbors certain microbes in their digestive systems. Enterobacter ludwigii is one of the gut-associated bacteria identified from field-collected caterpillars, and it has been shown to indirectly induce defenses in the dicot plant tomato by triggering the biosynthesis of salivary elicitors, but there are no clear mechanisms to show how gut microbes alter these salivary cues and how a different host plant responds to these inducible elicitors...
May 22, 2018: Journal of Chemical Ecology
https://www.readbyqxmd.com/read/29785551/salivary-duct-carcinoma-evaluation-of-treatment-and-outcome-in-a-tertiary-referral-institute
#5
Ann-Jean C C Beck, Peter J F M Lohuis, Abrahim Al-Mamgani, Laura A Smit, Willem M C Klop
PURPOSE: The aggressive behavior of salivary duct carcinoma (SDC) necessitates an aggressive treatment strategy, including surgery and radiotherapy (RT). We evaluated practice patterns and treatment outcomes in patients with SDC treated in our Institute. METHODS: Patients with SDC of the parotid or submandibular gland treated with curative intention in our Institute from 1998 until 2016 were reviewed. Our diagnostic workup and treatment strategy were evaluated together with treatment outcomes...
May 21, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29784466/knowledge-gaps-persist-and-hinder-progress-in-eliminating-mumps
#6
REVIEW
R Ramanathan, E A Voigt, R B Kennedy, G A Poland
Mumps, a common childhood disease in the pre-vaccine era that causes swelling of the parotid salivary glands, can lead to orchitis, viral meningitis, and sensorineural deafness. While the incidence of disease decreased dramatically after the vaccine was added to standard vaccination schedules, the disease has made a substantial resurgence in recent years. As a result, it becomes critical to examine the factors involved in recurring outbreaks. Although low and incomplete vaccination coverage may be a key reason, it does not fully explain the issue due to the high rate of occurrence in populations with high vaccination coverage rates...
May 18, 2018: Vaccine
https://www.readbyqxmd.com/read/29784082/novel-transgenic-pigs-with-enhanced-growth-and-reduced-environmental-impact
#7
Xianwei Zhang, Zicong Li, Huaqiang Yang, Dewu Liu, Gengyuan Cai, Guoling Li, Jianxin Mo, Dehua Wang, Cuili Zhong, Haoqiang Wang, Yue Sun, Junsong Shi, Enqin Zheng, Fanming Meng, Mao Zhang, Xiaoyan He, Rong Zhou, Jian Zhang, Miaorong Huang, Ran Zhang, Ning Li, Mingzhe Fan, Jinzeng Yang, Zhenfang Wu
In pig production, inefficient feed digestion causes excessive nutrients such as phosphorus and nitrogen to be released to the environment. To address the issue of environmental emissions, we established transgenic pigs harboring a single-copy quad-cistronic transgene and simultaneously expressing three microbial enzymes, β-glucanase, xylanase, and phytase in the salivary glands. All the transgenic enzymes were successfully expressed, and the digestion of non-starch polysaccharides (NSPs) and phytate in the feedstuff was enhanced...
May 22, 2018: ELife
https://www.readbyqxmd.com/read/29783677/measuring-cortisol-in-the-classroom-with-school-aged-children-a-systematic-review-and-recommendations
#8
REVIEW
Mirena Dimolareva, Nancy R Gee, Karen Pfeffer, Laëtitia Maréchal, Kyla Pennington, Kerstin Meints
The collection of salivary cortisol has been chosen as one of the least intrusive, easiest to collect, analyze, and store methods of obtaining information on physiological changes. It is, however, not clear what the best practice is when collecting salivary cortisol from children within the school setting. The aim of this systematic review is to evaluate the feasibility of cortisol collection in schools for future research and to make recommendations for best practice. The review included 25 peer-reviewed articles from seven databases...
May 18, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29782998/measurement-of-salivary-pepsin-for-diagnosis-of-gerd-in-adults-and-children-is-not-yet-ready-for-clinical-application
#9
Philip Woodland, Maartje Mj Singendonk, Joanne Ooi, Kornilia Nikaki, Terry Wong, Chung Lee, Esteban Glasinovic, Romy Koning, Rene Lutter, Marc A Benninga, Michiel P van Wijk, Daniel Sifrim
No abstract text is available yet for this article.
May 18, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29782810/chloride-and-sodium-ion-concentrations-in-saliva-and-sweat-as-a-method-to-diagnose-cystic-fibrosis
#10
Aline Cristina Gonçalves, Fernando Augusto Lima Marson, Regina Maria Holanda Mendonça, Carmen Sílvia Bertuzzo, Ilma Aparecida Paschoal, José Dirceu Ribeiro, Antônio Fernando Ribeiro, Carlos Emílio Levy
OBJECTIVE: Cystic fibrosis diagnosis is dependent on the chloride ion concentration in the sweat test (≥60mEq/mL - recognized as the gold standard indicator for cystic fibrosis diagnosis). Moreover, the salivary glands express the CFTR protein in the same manner as sweat glands. Given this context, the objective was to verify the correlation of saliva chloride concentration (SaCl) and sweat chloride concentration (SwCl), and between saliva sodium concentration (SaNa) and sweat sodium concentration (SwNa), in patients with cystic fibrosis and healthy control subjects, as a tool for cystic fibrosis diagnosis...
May 18, 2018: Jornal de Pediatria
https://www.readbyqxmd.com/read/29782688/oral-yeast-colonization-in-patients-with-primary-and-secondary-sj%C3%A3-gren-s-syndrome
#11
Clarissa Castro Galvão Medeiros, Luiz Gustavo Dos Anjos Borges, Karen Cherubini, Fernanda Gonçalves Salum, Renata Medina da Silva, Maria Antonia Zancanaro de Figueiredo
OBJECTIVE: The study aimed to investigate the pattern of oral yeast colonization of Sjögren's syndrome patients and its correlation to salivary flow rates, age and time of the disease progression. MATERIALS AND METHODS: Saliva and swab specimens were obtained from 45 patients (primary Sjögren's syndrome= 15/ secondary Sjögren's syndrome= 15/ healthy controls= 15). Yeast species were identified using culture method through chromogenic medium followed by polymerase chain reaction and Sanger sequencing...
May 21, 2018: Oral Diseases
https://www.readbyqxmd.com/read/29782435/biobehavioral-responses-of-preterm-infants-to-conventional-and-swaddled-tub-baths-a-randomized-crossover-trial
#12
Patrícia de Freitas, Mariana Bueno, Diane Holditch-Davis, Hudson Pires Santos, Amélia Fumiko Kimura
Bathing is a routine care procedure that exposes preterm infants to prolonged handling, which could cause stress and potentially disrupt infants' biobehavioral responses. The aim of this double-blind randomized crossover trial was to compare the preterm infant's body temperature, heart rate (HR), peripheral capillary oxygen saturation (SpO2), salivary cortisol levels, and sleep-wake states during and after swaddled and conventional tub baths. Forty-three infants born at 32 to 36 weeks postmenstrual age, weighing 2225 g or less, were enrolled in the study...
May 18, 2018: Journal of Perinatal & Neonatal Nursing
https://www.readbyqxmd.com/read/29781999/preparation-of-murine-submandibular-salivary-gland-for-upright-intravital-microscopy
#13
Xenia Ficht, Flavian Thelen, Bettina Stolp, Jens V Stein
The submandibular salivary gland (SMG) is one of the three major salivary glands, and is of interest for many different fields of biological research, including cell biology, oncology, dentistry, and immunology. The SMG is an exocrine gland comprised of secretory epithelial cells, myofibroblasts, endothelial cells, nerves, and extracellular matrix. Dynamic cellular processes in the rat and mouse SMG have previously been imaged, mostly using inverted multi-photon microscope systems. Here, we describe a straightforward protocol for the surgical preparation and stabilization of the murine SMG in anesthetized mice for in vivo imaging with upright multi-photon microscope systems...
May 7, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29781993/murine-salivary-functional-assessment-via-pilocarpine-stimulation-following-fractionated-radiation
#14
Jomy J Varghese, Isaac L Schmale, Mollie Eva Hansen, Shawn D Newlands, Danielle S W Benoit, Catherine E Ovitt
Hyposalivation is commonly observed in the autoimmune reaction of Sjögren's syndrome or following radiation injury to the major salivary glands. In these cases, questions remain regarding disease pathogenesis and effective interventions. An optimized technique that allows functional assessment of the salivary glands is invaluable for investigating exocrine gland biology, dysfunction, and therapeutics. Here, we present a step by step approach to performing pilocarpine stimulated saliva secretion, including tracheostomy and the dissection of the three major murine salivary glands...
May 4, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29781991/retroductal-nanoparticle-injection-to-the-murine-submandibular-gland
#15
Jomy J Varghese, Isaac L Schmale, Yuchen Wang, Mollie Eva Hansen, Shawn D Newlands, Catherine E Ovitt, Danielle S W Benoit
Two common goals of salivary gland therapeutics are prevention and cure of tissue dysfunction following either autoimmune or radiation injury. By locally delivering bioactive compounds to the salivary glands, greater tissue concentrations can be safely achieved versus systemic administration. Furthermore, off target tissue effects from extra-glandular accumulation of material can be dramatically reduced. In this regard, retroductal injection is a widely used method for investigating both salivary gland biology and pathophysiology...
May 3, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29781632/ethnicity-moderates-the-benefits-of-perceived-support-and-emotional-expressivity-on-stress-reactivity-for-asian-americans-and-euro-americans
#16
Shu-Wen Wang, Anna S Lau
OBJECTIVE: This study examined whether ethnicity moderated the benefits of perceived support and emotion expressivity on stress responses (cortisol, negative mood, task performance) during a lab stress task for Asian Americans and Euro Americans. We hypothesized that perceived support and emotion expressivity would be less beneficial for Asian Americans (relative to Euro Americans), for whom support seeking and emotional expressivity are less aligned with cultural values. METHOD: A majority female sample (72%) of 83 Asian American (first generation, n = 30; second generation, n = 53) and 50 Euro American college students completed the Trier Social Stress Test...
May 21, 2018: Cultural Diversity & Ethnic Minority Psychology
https://www.readbyqxmd.com/read/29781298/treatment-of-dental-biofilm-with-a-tincture-of-bauhinia-forficata-leaves-an-ex-vivo-study
#17
Julio Cesar C Ferreira-Filho, Andressa Temperini de Oliveira Marre, Juliana Soares de Sá Almeida, Leandro Araújo Lobo, Adriana Farah, Ana Maria Gondim Valença, Andréa Fonseca-Gonçalves
The inhibitory activity of a Bauhinia forficata tincture (TBF) was investigated against oral microorganism's strains and against a mature oral biofilm. The viability of planktonic cells was analyzed by Minimal Inhibitory and Microbicidal concentrations of TBF. Salivary samples from health volunteers were collected and mixed to form a saliva pool. An aliquot from this pool were seeded on membranes, which were incubated to form biofilm (48 h). The biofilm was treated according to the groups: G1-Chlorhexidine 0...
May 21, 2018: Natural Product Research
https://www.readbyqxmd.com/read/29780749/-rhipicephalus-bursa-sialotranscriptomic-response-to-blood-feeding-and-babesia-ovis-infection-identification-of-candidate-protective-antigens
#18
Sandra Antunes, Joana Couto, Joana Ferrolho, Fábio Rodrigues, João Nobre, Ana S Santos, M Margarida Santos-Silva, José de la Fuente, Ana Domingos
Ticks are among the most prevalent blood-feeding arthropods, and they act as vectors and reservoirs for numerous pathogens. Sialotranscriptomic characterizations of tick responses to blood feeding and pathogen infections can offer new insights into the molecular interplay occurring at the tick-host-pathogen interface. In the present study, we aimed to identify and characterize Rhipicephalus bursa salivary gland (SG) genes that were differentially expressed in response to blood feeding and Babesia ovis infection...
2018: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29780318/the-aerobic-and-cognitive-exercise-study-aces-for-community-dwelling-older-adults-with-or-at-risk-for-mild-cognitive-impairment-mci-neuropsychological-neurobiological-and-neuroimaging-outcomes-of-a-randomized-clinical-trial
#19
Cay Anderson-Hanley, Nicole M Barcelos, Earl A Zimmerman, Robert W Gillen, Mina Dunnam, Brian D Cohen, Vadim Yerokhin, Kenneth E Miller, David J Hayes, Paul J Arciero, Molly Maloney, Arthur F Kramer
Prior research has found that cognitive benefits of physical exercise and brain health in older adults may be enhanced when mental exercise is interactive simultaneously, as in exergaming. It is unclear whether the cognitive benefit can be maximized by increasing the degree of mental challenge during exercise. This randomized clinical trial (RCT), the Aerobic and Cognitive Exercise Study (ACES) sought to replicate and extend prior findings of added cognitive benefit from exergaming to those with or at risk for mild cognitive impairment (MCI)...
2018: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29780105/a-case-of-longstanding-igg4-related-ophthalmic-disease-dramatically-improved-after-steroid-therapy
#20
Yoko Hirata, Jiro Fukae, Akihiro Nishida, Shinsuke Fujioka, Mokoto Hamasaki, Masanari Nonokuma, Yoshio Tsuboi
A 61-year-old man was admitted to our hospital because of decreased visual acuity. On admission, he had marked blepharoedema, conjunctival injection, exophthalmos, diplopia, and blurred vision. He also had bronchial asthma and urinary retention requiring urethral catheterization. His serum immunoglobulin (Ig) G4 level was elevated to 1,830 U/mL. Fluorodeoxyglucose-positron emission tomography revealed an abnormal uptake in multiple organs. A histopathological examination of the salivary gland revealed IgG4-positive plasma cell infiltration, leading to a diagnosis of IgG4-related ophthalmic disease...
May 18, 2018: Internal Medicine
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