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Single ventricule

David O Udoh, Emmanuel Ibadin, Mojisola O Udoh
BACKGROUND: Intracranial abscess collections, though uncommon, are dreaded complications of head trauma, neurosurgical operations, meningitis, and otogenic, mastoid, and paranasal air sinus infections. Combining surgical evacuation with the appropriate antibiotic therapy is the effective treatment for intracranial abscesses. However, literature on surgical treatment is replete with several procedures which, on their own, may not. OBJECTIVES: To determine the epidemiology and outcomes (of various treatment modalities) of intracranial abscesses in our institution, a major referral center for neurosurgical conditions in the midwestern region of Nigeria...
October 2016: Asian Journal of Neurosurgery
Tulin Demir, Selcuk Kilic
Zika virus (ZIKV) is a single-stranded RNA virus in the Flaviviridae family and transmitted to human through infected mosquitos (Aedes aegypti and Aedes albopictus). Virus is closely related with other flaviviruses; dengue virus, yellow fever virus, West Nile virus, and Japanese encephalitis virus phylogenetically. Due to the possible relationship between virus and clinical features including microcephaly, ventricule, and eye deformities, Guillain-Barre syndrome increases the interest on this virus gradually...
November 2016: Folia Microbiologica
Thanh N Nguyen, Hesham Masoud, Nicholas Tarlov, James Holsapple, Lawrence S Chin, Alexander M Norbash
BACKGROUND: Very small ruptured aneurysms (≤3 mm) demonstrate a significant risk for procedural rupture with endovascular therapy. Since 2007, 1.5-mm-diameter coils have been available (Micrus, Microvention, and ev3), allowing neurointerventionalists the opportunity to offer patients with very small aneurysms endovascular treatment. In this study, we review the clinical and angiographic outcome of patients with very small ruptured aneurysms treated with the 1.5-mm coil. METHODS: This is a retrospective cohort study in which we examined consecutive ruptured very small aneurysms treated with coil embolization at a single institution...
October 2015: Interventional Neurology
Gillian C Braden, Rodolfo Ricart Arbona, Michelle Lepherd, Sébastien Monette, Aziz Toma, James G Fox, Floyd E Dewhirst, Neil S Lipman
During 1 year, experimentally naïve C57BL/6NCrl weanlings born to timed-pregnant dams from a single vendor demonstrated markedly increased mortality associated with runting, abnormal gait, and decreased activity. Gram-positive, aerobic, α-hemolytic, coccoid bacteria were isolated from the meninges (n = 16), blood (n = 1), and kidneys (n = 1) of clinically affected weanlings (n = 15); from the uterus (n = 1), meninges (n = 1), and oral cavity (n = 2) of 3 dams; and from the meninges and oral cavity of a clinically affected 86-d-old mouse in the same colony...
June 2015: Comparative Medicine
Sadaharu Tabuchi, Mitsutoshi Kadowaki
If not controlled in the early stage, ventriculitis is difficult to treat neurosurgically and can lead to serious sequelae, a long course of treatment, and hospitalization. We report two cases of ventriculitis and progressive hydrocephalus after shunt infection. Both were successfully treated by neuroendoscopic septostomy in combination with thorough intraventricular irrigation through a single burr hole followed by single shunt revision. Although surgical intervention has not been established as a first-choice treatment for ventriculitis, including early-stage ventriculitis, prompt neuroendoscopic surgery appears effective for the management of ventriculitis and hydrocephalus after shunt infection...
May 2015: Asian Journal of Endoscopic Surgery
Sunit Singhi, Ramesh Kumar, Pratibha Singhi, Muralidharan Jayashree, Arun Bansal
OBJECTIVE: Intracranial pressure monitoring can help in early identification of raised intracranial pressure and in setting more informed goals for treatment. We describe our 10-year experience of bedside burr holes performed by pediatric intensivists to establish intracranial pressure monitoring in children with CNS infections in a resource-limited setting and the technical difficulties and complications encountered. DESIGN: Descriptive study of prospectively recorded data...
June 2015: Pediatric Critical Care Medicine
Yasemin Benderli Cihan, Vedat Arsav
OBJECTIVE: This experimental study aims to investigate whether radiotherapy (RT) plus trastuzumab (T) followed by subsequent hormonotherapy increase the cumulative toxic effect on cardiac functions in rats. METHODS: A total of 70 Wistar-Albino female rats with a mean weight 213 ± 27 g were randomly divided into equal seven groups. The first group (C) underwent no procedure. The second group (RT) underwent the whole thoracic radiation including heart. The third group (T) was administered T through tail vein alone...
June 2014: Anadolu Kardiyoloji Dergisi: AKD, the Anatolian Journal of Cardiology
Arlete R Penitente, Rômulo D Novaes, Deoclécio A Chianca, Márcia F da Silva, Marcelo E Silva, Aline M A Souza, Silvia Guatimosim, Pedro W M Almeida, Márcia N M Alves, Leonardo B Felix, Clóvis A Neves, Antônio J Natali
Protein restriction (PR) is associated with cardiovascular diseases. The purpose of this study was to investigate the effects on single ventricular cardiomyocyte contractile function of a short-term PR after weaning. Male Fischer rats that were 28 days old were randomly divided into a control group (CG, n = 16) and a protein-restricted group (PRG, n = 16). After weaning, CG and PRG animals received isocaloric diets containing 15 and 6% protein, respectively, for 35 days. Biometric parameters were then measured, and the hearts were removed for the analysis of contractile function and calcium transient in isolated cardiomyocytes of the left ventricule (LV), and the quantification of calcium and collagen fibers in LV myocardium...
2013: Cells, Tissues, Organs
Cem Dinc, Ahmet Celal Iplikcioglu, Erdinc Ozek
AIM: The aim of this study was to retrospectively analyse the clinical, radiological features and surgical outcome of pineal epidermoid tumors treated at a single neurosurgical department. MATERIAL AND METHODS: We performed surgery on five patients with pineal region epidermoid tumors at a single neurosurgical department between the years 1998 and 2006. Headache, diplopia and ataxia were the most common presenting findings. Parinaud's syndrome was found in three patients...
2013: Turkish Neurosurgery
Andrew J Fabiano, Thomas J Gruber, Melissa S Baxter
OBJECTIVE: Intraventricular tissue plasminogen activator (alteplase) has been advocated for prevention of vasospasm in aneurysmal subarachnoid hemorrhage and treatment of traumatic or spontaneous intraventricular hemorrhage. External ventricular drain (EVD) insertion is often performed to manage increased intracranial pressure and hydrocephalus associated with these disease states. EVD-related ventriculitis is a serious infection with an up to 50% mortality rate. METHODS: We assessed the EVD infection rate in patients receiving intraventricular alteplase over a 12-month period...
November 2013: Clinical Neurology and Neurosurgery
M Ozbaran, T Yagdi, C Engin, S Erkul, O Balcioglu, B Baysal, S Nalbantgil, S Ertugay
BACKGROUND: The Berlin Heart EXCOR is a first-generation paracorporeal, pneumatic ventricular assist device that creates pulsatile flow. It can be used for long-term support of the left and/or right ventricule during end-stage heart failure. The aim of this study was to share our clinical experience in 54 patients. METHODS: Between April 2007 and August 2012, 54 patients with end-stage heart failure underwent Berlin Heart EXCOR ventricular assist device implantation, including 5 females and 9 children...
April 2013: Transplantation Proceedings
Rosemary J Rippon, Maurice R Alley, Isabel Castro
Nestling mortality in the endangered and endemic Hihi, also called Stitchbird (Notiomystis cincta), was studied over the 2008-09 breeding season at Zealandia-Karori Sanctuary, Wellington, New Zealand. Histopathology showed traumatic ventriculitis in seven of 25 (28%) dead nestlings. Single or multiple granulomas centered on chitinous insect remnants were found lodged within the gizzard mucosa, muscle layers, and ventricular or intestinal serosa. The insect remnants were confirmed as bee or wasp stings (Hymenoptera) using light and electron microscopy...
January 2013: Journal of Wildlife Diseases
Zeynep Kubilay, Shahram Amini, Loretta Litz Fauerbach, Lennox Archibald, William A Friedman, A Joseph Layon
OBJECT: Ventricular infection after ventriculostomy placement carries a high mortality rate. Responding to ventriculostomy infection rates, a multidisciplinary performance improvement team was formed, a comprehensive protocol for ventriculostomy placement was developed, and the efficacy was evaluated. METHODS: A best-practice protocol was developed, including hand hygiene before the procedure; prophylactic antibiotics; sterile gloves changed between preparation, draping, and procedure; hair removal by clipping for dressing adherence; skin preparation using iodine povacrylex (0...
March 2013: Journal of Neurosurgery
Mami Yamasaki, Masahiro Nonaka, Yohei Bamba, Chika Teramoto, Chiaki Ban, Ritsuko K Pooh
This study analyzed 156 cases of fetal hydrocephalus treated at Osaka National Hospital from 1992 to 2011 to review current methods for diagnosing and treating fetal hydrocephalus, and for estimating its clinical outcome. This was a retrospective study of a single institute (Osaka National Hospital). Of 156 cases in total, 37% were diagnosed as isolated ventriculomegaly, 50% as another type of malformation (36 cases of myelomeningocele, six of holoprosencephaly, three of Dandy-Walker syndrome, one case of Joubert syndrome, 12 of arachnoid cyst, nine of encephalocele, three of atresia of Monro and eight of corpus callosum agenesis, and 13% as secondary hydrocephalus...
December 2012: Seminars in Fetal & Neonatal Medicine
Soraya Naem, Robin S Houston, Gabriel Sentíes-Cué
Hadjelia truncata (Spirurida: Habronematidae) is a nematode found in the gizzard of several avian species. However, it has been reported pathogenic only in pigeons (Columba livia), in which it causes severe ventriculitis. Scanning electron microscopy (SEM) was used to study the morphological aspects of adult worms of this nematode in detail. Males and females measured 6.5-9 and 12-16.5 mm, respectively. The bodies were straight with moderate uniform thickness in both males and females, narrowing at the anterior end...
January 2013: Parasitology Research
Joon-Hyung Kim, Naman S Desai, Joseph Ricci, Philip E Stieg, Axel J Rosengart, Roger Härtl, Justin F Fraser
OBJECTIVE: Catheter-related infection remains a cause of morbidity in the use of external ventricular drains (EVDs). The aim of this retrospective single-center study was to assess the rate and factors related to ventriculostomy infections in the setting of the published literature. METHODS: Patients that underwent EVD placement in a single-center were retrospectively reviewed. Diagnosis, treatment, hospital course, and infection-related data were collected and analyzed in reference to ventriculitis rates...
January 2012: World Neurosurgery
Johannes Lemcke, Felix Depner, Ullrich Meier
BACKGROUND: Infection, i.e. meningitis or ventriculitis, is a major complication of external ventricular drainage (EVD). In order to prevent this complication rifampin-impregnated and clindamycin-impregnated silicone catheters and EVDs impregnated with nanoparticles of silver and an insoluble silver salt have been developed. Sparse data are published concerning the efficacy of these catheters in reducing bacterial colonization. METHODS: Between July 2003 and June 2006, 95 patients (age range 12-84 years, mean 53...
2012: Acta Neurochirurgica. Supplement
Ozlem Kucukhuseyin, Hulya Yilmaz-Aydogan, C Selim Isbir, Turgay Isbir
This study was carried out in 52 non-diabetic, 62 diabetic patients with coronary artery disease (CAD) and 55 controls. A Gly to Ser change RAGE gene was analyzed by PCR-RFLP techniques. GlyGly genotype frequency is higher in non-diabetics versus controls (P < 0.001). GlySer frequency is higher in diabetics than controls and non-diabetics (P < 0.001). Ser allele frequency is respectively increased in the order of diabetics > Controls > non-diabetics. These results reveals none association between Gly82Ser and the development of disease in non-diabetic patients...
April 2012: Molecular Biology Reports
Narendra Nathoo, Sameer S Nadvi, Pradeep K Narotam, James R van Dellen
OBJECTIVE: Brain abscess (BA) is a neurosurgical emergency and despite significant medical advances, it remains a surgical challenge. A single institution's two decade computed tomography era management experience with BA is reported. METHODS: A retrospective analysis of patients with BA, admitted to the Department of Neurosurgery, Wentworth Hospital, Durban, KwaZulu-Natal, South Africa, was performed. The medical records were analyzed for demographic, clinical, neuroimaging, neurosurgical and otolaryngology management, microbiological characteristics, and their relationship to outcome...
May 2011: World Neurosurgery
Hiroyuki Kashiwagi, Kenta Kumagai, Mutsumi Nozue
Most liver cysts are asymptomatic and tend to have a benign clinical course. However, symptomatic or complicated liver cysts sometimes require surgical intervention. The laparoscopic approach is crucial and provides definitive treatment for such cysts. Recently, a trend of laparoscopic procedure has been toward minimizing the number of incisions. We performed single incision laparoscopic surgery (SILS) for a huge liver cyst with chronic heart failure and thrombosis of the inferior vena cava. An 83 year-old female presented with a month-long history of general fatigue and loss of appetite...
April 2011: Tokai Journal of Experimental and Clinical Medicine
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