keyword
MENU ▼
Read by QxMD icon Read
search

Montone

keyword
https://www.readbyqxmd.com/read/28042333/nanosized-ucmsc-derived-extracellular-vesicles-but-not-conditioned-medium-exclusively-inhibit-the-inflammatory-response-of-stimulated-t-cells-implications-for-nanomedicine
#1
Marta Monguió-Tortajada, Santiago Roura, Carolina Gálvez-Montón, Josep Maria Pujal, Gemma Aran, Lucía Sanjurjo, Marcel la Franquesa, Maria-Rosa Sarrias, Antoni Bayes-Genis, Francesc E Borràs
Undesired immune responses have drastically hampered outcomes after allogeneic organ transplantation and cell therapy, and also lead to inflammatory diseases and autoimmunity. Umbilical cord mesenchymal stem cells (UCMSCs) have powerful regenerative and immunomodulatory potential, and their secreted extracellular vesicles (EVs) are envisaged as a promising natural source of nanoparticles to increase outcomes in organ transplantation and control inflammatory diseases. However, poor EV preparations containing highly-abundant soluble proteins may mask genuine vesicular-associated functions and provide misleading data...
2017: Theranostics
https://www.readbyqxmd.com/read/28004360/minimally-invasive-adipose-graft-transposition-procedure
#2
Carolina Gálvez-Montón, Paloma Gastelurrutia, Idoia Diaz-Güemes, Francisco M Sanchez-Margallo, Antoni Bayes-Genis
Recently, a new surgical technique to rescue infarcted myocardium (AGTP) has already tested (NCT01473433, AdiFLAP Trial). Here, we present the new minimally invasive AGTP (mi-AGTP) by thoracoscopy.
December 21, 2016: Journal of Cardiovascular Translational Research
https://www.readbyqxmd.com/read/27998847/the-failing-right-heart-implications-and-evolution-in-high-risk-patients-undergoing-transcatheter-aortic-valve-implantation
#3
Luca Testa, Azeem Latib, Federico De Marco, Marco De Carlo, Claudia Fiorina, Marco Barbanti, Rocco A Montone, Mauro Agnifili, Anna Sonia Petronio, Federica Ettori, Silvio Klugmann, Corrado Tamburino, Nedy Brambilla, Antonio Colombo, Francesco Bedogni
AIMS: Right ventricular dysfunction (RVdy) is negatively associated with survival after left heart valve surgery. It is unclear whether RVdy has the same impact in patients undergoing transcatheter aortic valve implantation (TAVI). We sought to evaluate the prognostic impact of different grades of RVdy on TAVI, with and without concomitant left ventricular dysfunction (LVdy), and the possible impact of TAVI on RVdy. METHODS AND RESULTS: Among 870 consecutive patients with severe symptomatic aortic stenosis undergoing TAVI, 226 patients (26%) presented with a concomitant diagnosis of RVdy...
December 20, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27983691/evaluation-of-google-glass-technical-limitations-on-their-integration-in-medical-systems
#4
Antonio Martinez-Millana, Jose-Luis Bayo-Monton, Aroa Lizondo, Carlos Fernandez-Llatas, Vicente Traver
Google Glass is a wearable sensor presented to facilitate access to information and assist while performing complex tasks. Despite the withdrawal of Google in supporting the product, today there are multiple applications and much research analyzing the potential impact of this technology in different fields of medicine. Google Glass satisfies the need of managing and having rapid access to real-time information in different health care scenarios. Among the most common applications are access to electronic medical records, display monitorizations, decision support and remote consultation in specialties ranging from ophthalmology to surgery and teaching...
December 15, 2016: Sensors
https://www.readbyqxmd.com/read/27931198/fdg-pet-parameters-predicting-mediastinal-malignancy-in-lung-cancer
#5
M Serra Fortuny, M Gallego, Ll Berna, C Montón, L Vigil, M J Masdeu, A Fernández-Villar, M I Botana, R Cordovilla, R García-Luján, E Cases, E Monsó
BACKGROUND: Staging of mediastinal lymph nodes in non-small cell lung cancer (NSCLC) is mandatory. The maximum Standard Uptake Value (SUVmax) obtained using F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) is the best non-invasive technique available for this evaluation, but its performance varies from center to center. The aim of the present study was to identify FDG-PET predictors of mediastinal malignancy that are able to minimize intercenter variability and improve the selection of subsequent staging procedures...
December 8, 2016: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/27930761/transoral-robotic-surgery-assisted-endoscopy-with-primary-site-detection-and-treatment-in-occult-mucosal-primaries
#6
Kyle M Hatten, Bert W O'Malley, Andres M Bur, Mihir R Patel, Christopher H Rassekh, Jason G Newman, Steven B Cannady, Ara A Chalian, Benjamin L Hodnett, Alexander Lin, John N Lukens, Roger B Cohen, Joshua M Bauml, Kathleen T Montone, Virginia A Livolsi, Gregory S Weinstein
Importance: Management of cervical lymph node metastasis without a known primary tumor is a diagnostic and treatment challenge for head and neck oncologists. Identification of the occult mucosal primary tumor minimizes the morbidity of treatment. Objective: To analyze the role of transoral robotic surgery (TORS) in facilitating the identification of a primary tumor site for patients presenting with squamous cell carcinoma of unknown primary (CUP). In addition, we assessed treatment deintensification by determining the number of patients who did not undergo definitive radiation therapy and chemotherapy...
December 8, 2016: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/27875711/corrigendum-to-external-conditions-inversely-change-the-rna-polymerase-ii-elongation-rate-and-density-in-yeast-biochim-biophys-acta-2013-nov-1829-11-1248-1255
#7
Ana Miguel, Fernando Montón, Tianlu Li, Fernando Gómez-Herreros, Sebastián Chávez, Paula Alepuz, José E Pérez-Ortín
No abstract text is available yet for this article.
December 24, 2016: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/27799762/c-reactive-protein-in-outpatients-with-acute-exacerbation-of-copd-its-relationship-with-microbial-etiology-and-severity
#8
Miguel Gallego, Xavier Pomares, Silvia Capilla, Maria Angeles Marcos, David Suárez, Eduard Monsó, Concepción Montón
BACKGROUND: C-reactive protein (CRP) measurement has proven valuable for detecting exacerbations, but its usefulness in predicting etiology remains controversial. Likewise, its potential value as a marker of severity, which is well established in patients with pneumonia, remains unproven in chronic obstructive pulmonary disease (COPD) exacerbations. METHODS: A cohort study of 118 patients with severe COPD and acute infectious exacerbations were included and followed up over 1 year...
2016: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/27783797/quality-of-life-related-factors-for-parents-of-children-with-hearing-loss
#9
Cristhiene Montone Nunes Ramires, Fátima Cristina Alves Branco-Barreiro, Érica Toledo Piza Peluso
Hearing loss among children, particularly those with severe and profound hearing impairment, has an effect on their communication and development, which in turn can have a significant impact on their parents. This study aimed to evaluate the quality of life of parents of children with hearing loss and identify the associated factors. A cross-sectional study was carried out involving parents of children that went through phonoaudiological therapy at a public university clinic in the city of São Paulo. The research instruments used were: the World Health Organization Quality of Life Instrument, Short Form (WHOQOL-bref), the Social Support Questionnaire 6 (SSQ-6) and the General Health Questionnaire (GHQ-12)...
October 2016: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/27767957/factors-essential-for-l-d-transpeptidase-mediated-peptidoglycan-cross-linking-and-%C3%AE-lactam-resistance-in-escherichia-coli
#10
Jean-Emmanuel Hugonnet, Dominique Mengin-Lecreulx, Alejandro Monton, Tanneke den Blaauwen, Etienne Carbonnelle, Carole Veckerlé, Yves Brun, Michael van Nieuwenhze, Christiane Bouchier, Kuyek Tu, Louis B Rice, Michel Arthur
The target of β-lactam antibiotics is the D,D-transpeptidase activity of penicillin-binding proteins (PBPs) for synthesis of 4→3 cross-links in the peptidoglycan of bacterial cell walls. Unusual 3→3 cross-links formed by L,D-transpeptidases were first detected in Escherichia coli more than four decades ago, however no phenotype has previously been associated with their synthesis. Here we show that production of the L,D-transpeptidase YcbB in combination with elevated synthesis of the (p)ppGpp alarmone by RelA lead to full bypass of the D,D-transpeptidase activity of PBPs and to broad-spectrum β-lactam resistance...
October 21, 2016: ELife
https://www.readbyqxmd.com/read/27717573/mercury-in-the-ecosystem-of-admiralty-bay-king-george-island-antarctica-occurrence-and-trophic-distribution
#11
Caio V Z Cipro, Rosalinda C Montone, Paco Bustamante
Mercury (Hg) can reach the environment through natural and human-related sources, threatening ecosystems all over the planet due to its well known deleterious effects. Therefore, Antarctic trophic webs, despite being relatively isolated, are not exempt of its influence. To evaluate Hg concentrations in an Antarctic ecosystem, different tissues from 2 species of invertebrates, 2 of fish, 8 of birds, 4 of pinnipeds and at least 5 of vegetation were investigated (n=176). For animals, values ranged from 0.018 to 48...
January 15, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/27686755/electromechanical-conditioning-of-adult-progenitor-cells-improves-recovery-of-cardiac-function-after-myocardial-infarction
#12
Aida Llucià-Valldeperas, Carolina Soler-Botija, Carolina Gálvez-Montón, Santiago Roura, Cristina Prat-Vidal, Isaac Perea-Gil, Benjamin Sanchez, Ramon Bragos, Gordana Vunjak-Novakovic, Antoni Bayes-Genis
: : Cardiac cells are subjected to mechanical and electrical forces, which regulate gene expression and cellular function. Therefore, in vitro electromechanical stimuli could benefit further integration of therapeutic cells into the myocardium. Our goals were (a) to study the viability of a tissue-engineered construct with cardiac adipose tissue-derived progenitor cells (cardiac ATDPCs) and (b) to examine the effect of electromechanically stimulated cardiac ATDPCs within a myocardial infarction (MI) model in mice for the first time...
September 29, 2016: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/27591138/noninvasive-assessment-of-an-engineered-bioactive-graft-in-myocardial-infarction-impact-on-cardiac-function-and-scar-healing
#13
Carolina Gálvez-Montón, Ramon Bragós, Carolina Soler-Boti Ja, Idoia Díaz-Güemes, Cristina Prat-Vidal, Verónica Crisóstomo, Francisco M Sánchez-Margallo, Aida Llucià-Valldeperas, Paco Bogónez-Franco, Isaac Perea-Gil, Santiago Roura, Antoni Bayes-Genis
: : Cardiac tissue engineering, which combines cells and biomaterials, is promising for limiting the sequelae of myocardial infarction (MI). We assessed myocardial function and scar evolution after implanting an engineered bioactive impedance graft (EBIG) in a swine MI model. The EBIG comprises a scaffold of decellularized human pericardium, green fluorescent protein-labeled porcine adipose tissue-derived progenitor cells (pATPCs), and a customized-design electrical impedance spectroscopy (EIS) monitoring system...
September 2, 2016: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/27572616/incidence-and-predictors-of-new-onset-atrioventricular-block-requiring-pacemaker-implantation-after-sutureless-aortic-valve-replacement
#14
Beatriz Toledano, Felipe Bisbal, Maria Luisa Camara, Carlos Labata, Elisabet Berastegui, Carolina Gálvez-Montón, Roger Villuendas, Axel Sarrias, Teresa Oliveres, Damià Pereferrer, Xavier Ruyra, Antoni Bayés-Genís
OBJECTIVES: In high-risk patients with severe aortic stenosis, aortic valve replacement (AVR) with a sutureless Perceval prosthesis (SU-AVR) can be performed instead of conventional AVR or transcatheter aortic valve implantation. Little data are available regarding postoperative conduction disorders after SU-AVR. We aimed to determine the incidence and predictors of new-onset complete atrioventricular block (NO-AVB) requiring permanent cardiac stimulation following SU-AVR. METHODS: We studied consecutive patients who underwent SU-AVR between 2013 and 2015...
December 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/27550813/suppression-of-microrna-200-family-expression-by-oncogenic-kras-activation-promotes-cell-survival-and-epithelial-mesenchymal-transition-in-kras-driven-cancer
#15
Xiaomin Zhong, Lan Zheng, Jianfeng Shen, Dongmei Zhang, Minmin Xiong, Youyou Zhang, Xinhong He, Janos L Tanyi, Feng Yang, Kathleen T Montone, Xiaojun Chen, Congjian Xu, Andy P Xiang, Qihong Huang, Xiaowei Xu, Lin Zhang
Oncogenic KRAS contributes to malignant transformation, antiapoptosis, and metastasis in multiple human cancers, such as lung, colon, and pancreatic cancers and melanoma. MicroRNAs (miRNAs) are endogenous 18- to 25-nucleotide noncoding small RNAs that regulate gene expression in a sequence-specific manner via the degradation of target mRNAs or inhibition of protein translation. In the present study, using array-based miRNA profiling in IMR90 and MCF10A cells expressing oncogenic KRAS, we identified that the expression of the microRNA 200 (mir-200) family was suppressed by KRAS activation and that this suppression was mediated by the transcription factors JUN and SP1 in addition to ZEB1...
November 1, 2016: Molecular and Cellular Biology
https://www.readbyqxmd.com/read/27519756/occurrence-of-organochlorines-in-the-green-sea-turtle-chelonia-mydas-on-the-northern-coast-of-the-state-of-s%C3%A3-o-paulo-brazil
#16
Josilene da Silva, Satie Taniguchi, José Henrique Becker, Max Rondon Werneck, Rosalinda Carmela Montone
Organochlorines (OCs), such as pesticides and polychlorinated biphenyls (PCBs), are persistent, toxic and widely distributed through atmospheric transport and ocean currents. Few studies have been conducted on OCs in sea turtles, especially on the coast of Brazil. Chelonia mydas is the largest hard-shell sea turtle and is found tropical and subtropical regions in all oceans. The aim of the present study was to determine the occurrence of OCs in the green sea turtle (C. mydas). Fat, liver, kidney and muscle samples were collected from 27 juveniles found on the beach of the city of Ubatuba on the northern coast of the state of São Paulo, Brazil...
November 15, 2016: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/27518570/yeasts-from-macroalgae-and-lichens-that-inhabit-the-south-shetland-islands-antarctica
#17
Alysson Wagner Fernandes Duarte, Michel Rodrigo Zambrano Passarini, Tiago Palladino Delforno, Franciane Maria Pellizzari, Caio Vinicius Zecchin Cipro, Rosalinda Carmela Montone, Maria Virginia Petry, Jair Putzke, Luiz Henrique Rosa, Lara Durães Sette
Antarctic terrestrial ecosystems are largely dominated by lichens, while shallow coastal environments are mainly covered by macroalgae. The aim of this study was to isolate and to evaluate the diversity of yeasts in different species of macroalgae and lichens collected in South Shetland Islands, Antarctica. A total of 405 yeasts were recovered (205 from macroalgae and 200 from lichens). The yeast community from macroalgae was most diversity than the yeast community from lichen. The dominance index was similar for both substrates...
August 12, 2016: Environmental Microbiology Reports
https://www.readbyqxmd.com/read/27515332/cardiac-tissue-engineering-lost-in-translation-or-ready-for-translation
#18
EDITORIAL
Antoni Bayés-Genís, Carolina Gálvez-Montón, Santiago Roura
No abstract text is available yet for this article.
August 16, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27488530/jarid1b-enables-transit-between-distinct-states-of-the-stem-like-cell-population-in-oral-cancers
#19
Nicole D Facompre, Kayla M Harmeyer, Xavier Sole, Sheheryar Kabraji, Zachary Belden, Varun Sahu, Kelly Whelan, Koji Tanaka, Gregory S Weinstein, Kathleen T Montone, Alexander Roesch, Phyllis A Gimotty, Meenhard Herlyn, Anil K Rustgi, Hiroshi Nakagawa, Sridhar Ramaswamy, Devraj Basu
The degree of heterogeneity among cancer stem cells (CSC) remains ill-defined and may hinder effective anti-CSC therapy. Evaluation of oral cancers for such heterogeneity identified two compartments within the CSC pool. One compartment was detected using a reporter for expression of the H3K4me3 demethylase JARID1B to isolate a JARID1B(high) fraction of cells with stem cell-like function. JARID1B(high) cells expressed oral CSC markers including CD44 and ALDH1 and showed increased PI3K pathway activation. They were distinguished from a fraction in a G0-like cell-cycle state characterized by low reactive oxygen species and suppressed PI3K/AKT signaling...
September 15, 2016: Cancer Research
https://www.readbyqxmd.com/read/27412870/coronary-bioresorbable-vascular-scaffold-use-in-the-treatment-of-coronary-artery-disease
#20
Luca Testa, Azeem Latib, Rocco A Montone, Antonio Colombo, Francesco Bedogni
Bioresorbable vascular scaffolds (BVS) represent a promising novel approach for the treatment of coronary artery disease. BVS promise to address some of the well-known limitations of current drug-eluting stents, while providing a transient scaffolding of the vessel to prevent acute vessel closure/recoil. Drug elution by BVS prevents neointimal proliferation in a similar fashion to drug-eluting stents, and complete bioresorption is associated with late vessel lumen enlargement, plaque regression, and restoration of vasomotion...
July 2016: Circulation. Cardiovascular Interventions
keyword
keyword
28937
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"