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Anaphylactic shock

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https://www.readbyqxmd.com/read/27890557/anaphylaxis-in-a-health-maintenance-organization-international-classification-of-diseases-coding-and-epinephrine-auto-injector-prescribing
#1
Deena Pourang, Michael Batech, Javed Sheikh, Shefali Samant, Michael Kaplan
BACKGROUND: Accurate estimates of the incidence of anaphylaxis are limited. Current International Classification of Diseases, Ninth Revision (ICD-9) codes complicate accurate diagnosis of anaphylaxis and assessment of appropriate epinephrine prescribing. OBJECTIVE: To quantify the incidence and demographic character of patients with anaphylaxis-related ICD-9 codes in a large health maintenance organization and analyze epinephrine prescribing and dispensing rates...
November 24, 2016: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/27871512/case-report-management-of-differential-diagnosis-and-treatment-of-severe-anaphylaxis-in-the-setting-of-spinal-anesthesia
#2
Brian M Osman, Joni M Maga, Sebastian M Baquero
The purpose of this case report is to educate fellow anesthesiologists of a complicated differential diagnosis for sudden cardiovascular collapse after spinal anesthesia. We report a case where anaphylaxis occurred while under spinal anesthesia and resulted in difficult resuscitation. A 58-year-old woman undergoing bilateral knee replacements under spinal anesthesia experienced sudden seizure and cardiovascular collapse from acute anaphylactic shock while administering a cephalosporin. Local anesthetic toxicity, high spinal, and anaphylaxis were considered due to overlapping of symptoms...
December 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27857995/anaphylaxis-after-intravenous-infusion-of-dexketoprofen-trometamol
#3
Sertac Guler, Ilyas Ertok, Nurdan Yilmaz Sahin, Hayri Ramadan, Yavuz Katirci
Dexketoprofen trometamol (DT), a nonsteroidal anti-inflammatory drug, is a highly water-soluble salt and active enantiomer of rac-ketoprofen. Its parenteral form is commonly used for acute pain management in emergency departments of our country. Side effects such as diarrhea, indigestion, nausea, stomach pain, and vomiting may be seen after the use of DT. Anaphylactic shock (AS) secondary to infusion of DT is very rare and, to our knowledge, it is the first case report describing this side effect. This case report was presented to emphasize that AS may be seen after the use of DT...
September 2016: Turkish Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27857993/acute-ischemic-stroke-and-severe-multiorgan-dysfunction-due-to-multiple-bee-stings
#4
Murat Guzel, Handan Akar, Ali Kemal Erenler, Ahmet Baydin, Abdulcelil Kayabas
Various manifestations after bee sting have been described. Local reactions, such as pain, wheal, flare, edema and swelling, are common and generally self-limiting. Uncommonly manifestations like vomiting, diarrhea, dyspnea, generalized edema, acute renal failure, anaphylactic shock, myocardial infarction, hypotension, collapse, pulmonary hemorrhage, acute hemorrhagic pancreatitis, and atrial fibrillation may occur. We report a 59 year-old man who sustained ischemic stroke and multi-organ dysfunction following multiple bee stings...
September 2016: Turkish Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27853881/a-suspected-case-of-rocuronium-sugammadex-complex-induced-anaphylactic-shock-after-cesarean-section
#5
Masakazu Yamaoka, Miki Deguchi, Kiichiro Ninomiya, Toshiaki Kurasako, Mutsuko Matsumoto
An anaphylactic reaction during a cesarean section occurs rarely, and rocuronium is thought to be one of the common agents causing perioperative anaphylaxis. Here we report an anaphylactic shock after cesarean section that is suggested to be induced by the rocuronium-sugammadex complex. A 36-year-old primigravida underwent an elective cesarean section under general anesthesia due to placenta previa. While the operation was completed uneventfully, she developed anaphylactic shock following sugammadex administration...
November 16, 2016: Journal of Anesthesia
https://www.readbyqxmd.com/read/27851507/1872-use-of-methylene-blue-in-chemotherapy-induced-refractory-anaphylactic-shock
#6
Cynthia Tsai, Angela Slampak-Cindric, Jason Stamm
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27851381/1746-maternal-anaphylactic-shock-with-breast-feeding-in-the-immediate-postpartum-period
#7
Muhammad Bilal Khalid, Salman Bin Mahmood, Hina Farooq, Rajat Kapoor, Omar Rahman, Christopher Lehmann
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27845058/identification-of-the-immunogenic-epitopes-of-the-whole-venom-component-of-the-hemiscorpius-lepturus-scorpion-using-the-phage-display-peptide-library
#8
Roghaye Jahdasani, Fatemeh Rahimi Jamnani, Mahdi Behdani, Mahdi Habibi-Anbouhi, Najmeh Yardehnavi, Delavar Shahbazzadeh, Fatemeh Kazemi-Lomedasht
The venom of the Hemiscorpius lepturus scorpion contains mixtures of bioactive compounds that disturb biochemical and physiological functions of the victims. Hemiscorpius lepturus envenomation is recognized as a serious health concern in tropical regions. So far, there is no preventive procedure, and the main focus is on treatment of victims with an antiserum purified from hyper-immunized horses. Although antisera can neutralize the venom, they, in some cases, lead to anaphylactic shock and even death. Selection of peptides mimicking antigenic and immunogenic epitopes of toxins from random peptide libraries is a novel approach for the development of recombinant toxins and poly-epitopic vaccine...
December 15, 2016: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/27822310/anaphylactic-shock-during-cement-implantation-of-a-total-hip-arthroplasty-in-a-patient-with-underlying-mastocytosis-case-report-of-a-rare-intraoperative-complication
#9
Anita Ten Hagen, Pieter Doldersum, Tom van Raaij
BACKGROUND: Cemented total hip arthroplasty (THA) is a safe and common procedure. In rare cases life threatening bone cement implantation syndrome (BCIS) may occur, which is commonly caused by pulmonary embolism (PE). CASE PRESENTATION: We describe the rare case of a 70-year old patient who underwent an elective total hip replacement. Before surgery he was diagnosed with underlying systemic indolent mastocytosis, a rare pathological disorder that may result in anaphylaxis after massive systemic mast cell activation...
2016: Patient Safety in Surgery
https://www.readbyqxmd.com/read/27749688/hla-a-02-alleles-are-associated-with-tetanus-antitoxin-induced-exanthematous-drug-eruptions-in-chinese-patients
#10
Sijia Yan, Sheng-An Chen, Wen Zhang, Fanping Yang, Ying Yang, Qinyuan Zhu, Huizhong Zhu, Xinfen Sun, Menglin Jiang, Yu Su, Lirong Zhang, Qinghe Xing, Xiaoqun Luo
OBJECTIVE: Tetanus antitoxin (TAT) is an effective antitetanus medicine, but may sometimes cause adverse drug reactions such as rapid-onset anaphylactic shock and late-onset cutaneous adverse drug reactions, including exanthematous drug eruptions (EDE). Human leukocyte antigen (HLA) class I alleles are strongly associated with different types of cutaneous adverse drug reactions. This study aimed to assess whether there is an association between TAT-induced EDE and HLA-A, HLA-B, and HLA-C alleles in the Chinese Han population...
October 5, 2016: Pharmacogenetics and Genomics
https://www.readbyqxmd.com/read/27746328/characterization-of-the-potential-allergenicity-of-irradiated-bovine-%C3%AE-lactalbumin-in-a-balb-c-mouse-model
#11
Xuanyi Meng, Xin Li, Jinyan Gao, Hongbing Chen
Bovine α-lactalbumin (ALA) is a known food allergen present in milk to induce anaphylaxis. A previous study demonstrated that irradiated ALA (iALA) decreased the IgE-binding properties and weakened the degranulation capacity of basophils in vitro. The present study aimed to further assess the potential allergenicity of iALA in vivo in a BALB/c mouse model. The mice (n = 10/group) were intragastrically sensitized and orally challenged with either iALA or ALA using cholera toxin as adjuvant. In contrast to the ALA group, the iALA group did not show anaphylactic shock symptoms...
October 13, 2016: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/27712573/diagnosing-%C3%AE-lactam-hypersensitivity
#12
Francesco Gaeta, Maria J Torres, Rocco Luigi Valluzzi, Cristiano Caruso, Cristobalina Mayorga, Antonino Romano
Hypersensitivity reactions to β-lactam antibiotics are commonly reported. They can be classified as immediate or non-immediate according to the time interval between the last drug administration and their onset. Immediate reactions occur within one hour after the last drug administration and are manifested clinically by urticaria and/or angioedema, rhinitis, bronchospasm, and anaphylactic shock; they may be mediated by specific IgE-antibodies. Non-immediate reactions occur more than one hour after the last drug administration...
October 4, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27703633/anaphylactic-shock-caused-by-intramuscular-injection-of-midazolam-during-the-perioperative-period-a-case-report
#13
Kyu Nam Kim, Dong Won Kim, Yeong Hun Sin, Soo Kyung Lee
Although anaphylactic shock during the perioperative period is rare, it can be lethal due to severe cardiovascular and respiratory collapse. Midazolam is generally used as premedication for relieving anxiety about the operation, and the danger of anaphylactic shock after intramuscular injection is not widely recognized. We report the first case of anaphylactic shock occurring during the perioperative period after intramuscular injection of midazolam. Since anaphylactic shock after intramuscular injection can be of slow onset, the operation should be delayed if an anaphylactic reaction is suspected, even if the symptoms are limited...
October 2016: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/27692979/fatal-kounis-syndrome-with-stent-thrombosis-secondary-to-amoxicillin-clavulanic-acid-use-a-case-report-and-literature-review
#14
Issam Salouage, Sihem El Aidli, Sarra Kastalli, Riadh Daghfous, Mohamed Lakhal
Anaphylactic reactions are often induced by drugs, and the most frequent ones are penicillin derivates. The concurrence of acute coronary syndrome with hypersensitivity and anaphylactic or anaphylactoid reactions constitutes the Kounis syndrome. We report a case of a coronary stent thrombosis with a fatal outcome complicating an anaphylactic shock induced by amoxicillin-clavulanic acid association. A 58-year-old woman with a history of triple coronary stenting was treated by amoxicillin/clavulanic acid association for pharyngitis...
July 21, 2016: Thérapie
https://www.readbyqxmd.com/read/27687465/chlorhexidine-related-refractory-anaphylactic-shock-a-case-successfully-resuscitated-with-extracorporeal-membrane-oxygenation
#15
Man-Ling Wang, Ching-Tao Chang, Hsing-Hao Huang, Yu-Chang Yeh, Tzong-Shiun Lee, Kuan-Yu Hung
IMPORTANCE: We report a patient with a life-threatening anaphylactic reaction to a chlorhexidine-coated central venous catheter, confirmed with a high serum level of chlorhexidine-specific IgE. To our knowledge, this is the first case successfully resuscitated using extracorporeal membrane oxygenation (ECMO). Great caution is required when using chlorhexidine and chlorhexidine-impregnated catheters, given that its widespread use has the potential to sensitize certain patients and may result in life-threatening anaphylaxis on subsequent exposure...
November 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27671457/anaphylactic-reaction-during-implantation-of-ovation-abdominal-stent-graft-in-patients-with-abdominal-aortic-aneurysm
#16
Andrea Siani, Federico Accrocca, Gennaro De Vivo, Federica Mounayergi, Luca Maria Siani, Roberto Antonelli
The Ovation Abdominal Stent Graft System is a trimodular endoprosthesis planned to overcome the limitations of currently available stent grafts, allowing complex iliac and femoral access and providing a proximal seal in challenge infrarenal neck morphology. The proximal sealing is achieved by means of a network of inflatable rings filled with low-viscosity radiopaque polyethylene glycol-based polymer during stent-graft deployment. The leakage of polymer outside the channel to fill the rings into the vascular system may induce an hypersensitivity reaction and anaphylactic shock...
September 23, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27668164/cardiac-arrest-caused-by-nafamostat-mesilate
#17
Hyo Shik Kim, Kyung Eun Lee, Ji Hyun Oh, Chan Sung Jung, Dughyun Choi, Yunsuek Kim, Jin Seok Jeon, Dong Cheol Han, Hyunjin Noh
A 65-year-old man was transferred from the Department of Vascular Surgery to Nephrology because of cardiac arrest during hemodialysis. He underwent incision and drainage for treatment of a buttock abscess. Nafamostat mesilate was used as an anticoagulant for hemodialysis to address bleeding from the incision and drainage site. Sudden cardiac arrest occurred after 15 minutes of dialysis. The patient was treated in the intensive care unit for 5 days. Continuous veno-venous hemodiafiltration was started without any anticoagulant in the intensive care unit...
September 2016: Kidney Research and Clinical Practice
https://www.readbyqxmd.com/read/27629741/induction-and-maintenance-infliximab-therapy-for-the-treatment-of-crohn-s-disease-with-perianal-fistulas-in-children-retrospective-multicenter-study
#18
Barbara M Iwańczak, Józef Ryżko, Piotr Jankowski, Małgorzata Sładek, Agata Wasilewska, Mariusz Szczepanik, Edyta Sienkiewicz, Anna Szaflarska-Popławska, Sabina Więcek, Jarosław Kwiecień, Bartosz Korczowski, Jolanta Maślana
BACKGROUND: Infliximab is a biological drug used for the treatment of Crohn's disease in children. OBJECTIVES: The aim of this retrospective study was the estimation of effectiveness and safety of infliximab in the treatment of Crohn's disease with perianal fistulas in children. MATERIAL AND METHODS: Analysis comprised 50 children with Crohn's disease with perianal fistulas aged 9 to 18 years (16 girls and 34 boys) who failed to respond to conventional therapy...
May 2016: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/27616176/incidence-of-apnea-attack-as-allergic-reaction-after-oral-food-challenge-in-patient-with-ige-mediated-wheat-allergy
#19
Masayuki Akashi
Anaphylaxis is a severe allergic reaction that is rapid in onset and might cause death. Although wheezes, dyspnea or loss of consciousness are known to occur with severe allergic reactions with IgE-mediated food allergy, reports of apnea attack associated with IgE-mediated food allergy are rare. In this case, 9-year-old boy with IgE-mediated wheat allergy experienced apnea attack with strong desaturation after an immediate allergic reaction including erythema, abdominal pain, vomiting, and anaphylactic shock...
August 2016: Arerugī, [Allergy]
https://www.readbyqxmd.com/read/27600879/rational-design-and-engineering-of-a-mutant-variant-of-urate-oxidase-as-a-therapeutic-enzyme-a-molecular-dynamics-simulation-approach
#20
Sajjad Ahrari, Fatemeh Dabbagh, Sobhan Ahrari, Younes Ghasemi, Navid Mogharrab, Yasser Riazalhosseini
BACKGROUND: Urate oxidase is absent in humans so the enzyme is considered as an important therapeutic agent to control hyperuricemic disorders. Currently available enzymes with pharmaceutical applications have adverse effects associated with allergic reactions and anaphylactic shocks, in case of chronic treatment. Therefore, developing variant forms of the enzyme, with lower immunogenicity and similar or higher activity, is of great importance. AIM: Here, we tried to improve the structure of a recently resurrected ancestral mammalian urate oxidase (which is claimed to have higher enzymatic activity compared to other mammalian counterparts) by introducing eight rational mutations and verified the consequence of these mutations on immunogenicity, stability and the affinity of protein to uric acid by computational techniques...
September 5, 2016: Current Computer-aided Drug Design
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