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https://www.readbyqxmd.com/read/29681566/off-pump-coronary-artery-bypass-grafting-with-mini-sternotomy-in-the-treatment-of-triple-vessel-coronary-artery-disease
#1
Pixiong Su, Song Gu, Yan Liu, Xitao Zhang, Jun Yan, Xiangguang An, Jie Gao, Yue Xin, Jian Zhou
We have developed off-pump coronary artery bypass approach with lower distal mini-sternotomy (TM-OPCAB) for multivessel coronary revascularization. The aim of this retrospective study is to provide evidence for the feasibility and safety of this technique in the treatment of triple-vessel diseases.Two hundred eighty-eight patients with triple-vessel coronary artery disease who underwent TM-OPCAB or standard off-pump coronary artery bypass surgery (S-OPCAB) were included in this study after propensity-score matching...
April 20, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29678350/better-surgical-outcome-by-image-guided-navigation-system-in-endoscopic-removal-of-sinonasal-inverted-papilloma
#2
Sang Hyeon Ahn, Eun Jung Lee, Jin Won Kim, Kwang Ha Baek, Hyung-Ju Cho, Joo-Heon Yoon, Chang-Hoon Kim
PURPOSE: The purpose of this study was to validate and compare treatment outcomes for endoscopic resection of sinonasal inverted papilloma (IP) with or without the use of a navigation system. MATERIALS AND METHODS: A total of 58 patients who underwent endoscopic resection of sinonasal inverted papilloma by a single surgeon from 2007 to 2016 at our institution were retrospectively reviewed. Depending on the use of the navigation system, subjects were divided into two groups: a conventional endoscopic resection group without navigation system (CER group) and a navigation-assisted endoscopic resection group (NER group)...
March 28, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29678158/dexmedetomidine-infusion-as-an-analgesic-adjuvant-during-laparoscopic-%C3%B1-holecystectomy-a-randomized-controlled-study
#3
Kateryna Bielka, Iurii Kuchyn, Volodymyr Babych, Kseniia Martycshenko, Oleksii Inozemtsev
BACKGROUND: Dexmedetomidine (DEX) has sedative, sympatholytic and analgesic effects and might be beneficial if used as an adjuvant to: improve analgesia; modulate haemodynamic responses to intubation and pneumoperitoneum and; reduce the number of opioid-associated adverse events. The aim of this study was to evaluate the efficacy and safety of DEX infusion during elective laparoscopic cholecystectomy (LC). METHODS: A randomized, single-centre, parallel-group, placebo-controlled study was carried out between May 2016 and June 2017...
April 20, 2018: BMC Anesthesiology
https://www.readbyqxmd.com/read/29671247/histopathological-features-to-define-atypical-meningioma-what-does-really-matter-for-prognosis
#4
Valeria Barresi, Simona Lionti, Samuel Caliri, Maria Caffo
Atypical meningiomas are diagnosed in the presence of: (1) three or more of the following minor atypical criteria: increased cellularity, small cells with a high nuclear/cytoplasmic ratio, prominent nucleoli, sheeting, and foci of spontaneous or geographic necrosis; (2) mitotic count ≥ 4 mitoses per 10 HPF (high mitotic index); (3) brain invasion. The 5-year disease-free survival (DFS) is around 50%. Due to their heterogeneous behavior, the post-surgical treatment of atypical meningiomas is controversial...
April 18, 2018: Brain Tumor Pathology
https://www.readbyqxmd.com/read/29671038/-18-f-fdg-pet-and-high-resolution-mri-co-registration-for-pre-surgical-evaluation-of-patients-with-conventional-mri-negative-refractory-extra-temporal-lobe-epilepsy
#5
Yao Ding, Yuankai Zhu, Biao Jiang, Yongji Zhou, Bo Jin, Haifeng Hou, Shuang Wu, Junming Zhu, Zhong Irene Wang, Chong H Wong, Meiping Ding, Hong Zhang, Shuang Wang, Mei Tian
PURPOSE: Epilepsy that originates outside of the temporal lobe can present some of the most challenging problems for surgical therapy, especially for patients with conventional magnetic resonance imaging (MRI)-negative refractory extra-temporal lobe epilepsy (ETLE). This study aimed to evaluate the clinical value of pre-surgical 18 F-fluoro-deoxy-glucose positron emission tomography (18 F-FDG PET) and high-resolution MRI (HR-MRI) co-registration in patients with conventional MRI-negative refractory ETLE, and compare their surgical outcomes...
April 18, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29665710/significance-of-incidental-intra-articular-and-peri-articular-fdg-avid-foci-on-pet-ct
#6
Wayne B Cohen-Levy, Juan Pretell-Mazzini, Adam D Singer, Ty Subhawong, Dylan N Greif, Jean Jose
Background Positron emission tomography/computed tomography (PET/CT) is a useful imaging adjunct in patients with sarcoma. Intra-articular and peri-articular 18F-fluoro-2-deoxy-D-glucose (FDG) avid lesions are often discovered incidentally. Purpose To describe the etiology, appearance, and standardized uptake values (SUV) of incidentally detected FDG avid intra-articular and peri-articular foci in patients with sarcoma. Material and Methods The institutional sarcoma database between November 2011 and November 2016 was retrospectively reviewed...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29665643/evaluation-of-the-effects-of-iranian-propolis-on-the-severity-of-post-operational-induced-peritoneal-adhesion-in-rats
#7
Vahid Reza Askari, Vafa Baradaran Rahimi, Parvin Zamani, Narges Fereydouni, Pouria Rahmanian-Devin, Amir Hossein Sahebkar, Hassan Rakhshandeh
BACKGROUND: Peritoneal adhesion is a major complication of surgery that can lead to serious problems such as bowel obstruction, pain, infertility and even mortality. Propolis is a honey bee product with anti-inflammatory and anti-oxidant activities that could potentially protect against adhesive surgical complications. METHODS: Forty 8-weeks-old rats (275 ± 25 g) were divided into five groups: normal group without any surgical procedure, and experimental groups treated with normal saline, 50 mg/kg, 100 mg/kg and 200 mg/kg of propolis...
March 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29662560/impact-of-68-ga-dota-peptide-pet-ct-on-the-management-of-gastrointestinal-neuroendocrine-tumour-gi-net-malaysian-national-referral-centre-experience
#8
Teik Hin Tan, Ching Yeen Boey, Boon Nang Lee
Purpose: The National Cancer Institute is the only referral centre in Malaysia that provides 68 Ga-DOTA-peptide imaging. The purpose of this study is to determine the impact of 68 Ga-DOTA-peptide PET/CT on the management of gastrointestinal neuroendocrine tumours (GI-NET). Materials and Methods: A cross-sectional study was performed to review the impact of 68 Ga-DOTA-peptide (68 Ga-DOTATATE or 68 Ga-DOTATOC) PET/CT on patients with biopsy-proven GI-NET between January 2011 and December 2015...
April 2018: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29660355/intrapleural-therapy-for-empyema-in-the-setting-of-a-bronchopleural-fistula-a-novel-use-of-an-intrabronchial-valve
#9
Nikita Leiter, Edward M Pickering, Yashvir S Sangwan, Whitney M Burrows, Joseph S Friedberg, Ashutosh Sachdeva
Post-surgical empyema with bronchopleural fistula can be difficult to manage. We present a case of post-operative empyema with bronchopleural fistula that was successfully treated non-operatively by placing an intrabronchial valve to address the bronchopleural fistula, which allowed for safe administration of intrapleural fibrinolytics and antibiotics for definite treatment of the empyema. While the presence of a bronchopleural fistula is considered a contraindication to the administration of intrapleural tissue plasminogen activator and deoxyribonuclease, this case demonstrates a novel use of the intrabronchial valve that could allow these medications to be used...
April 13, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29660006/validation-of-post-operative-residual-contrast-enhancing-tumor-volume-as-an-independent-prognostic-factor-for-overall-survival-in-newly-diagnosed-glioblastoma
#10
Benjamin M Ellingson, Lauren E Abrey, Sarah J Nelson, Timothy J Kaufmann, Josep Garcia, Olivier Chinot, Frank Saran, Ryo Nishikawa, Roger Henriksson, Warren P Mason, Wolfgang Wick, Nicholas Butowski, Keith L Ligon, Elizabeth R Gerstner, Howard Colman, John de Groot, Susan Chang, Ingo Mellinghoff, Robert J Young, Brian M Alexander, Rivka Colen, Jennie W Taylor, Isabel Arrillaga-Romany, Arnav Mehta, Raymond Y Huang, Whitney B Pope, David Reardon, Tracy Batchelor, Michael Prados, Evanthia Galanis, Patrick Y Wen, Timothy F Cloughesy
Background: In the current study, we pooled imaging data in newly diagnosed GBM patients from international multicenter clinical trials, single institution databases, and multicenter clinical trial consortiums to identify the relationship between post-operative residual enhancing tumor volume and overall survival (OS). Methods: Data from 1,511 newly diagnosed GBM patients from 5 data sources were included in the current study: 1) a single institution database from UCLA (N=398; Discovery); 2) patients from the Ben and Cathy Ivy Foundation for Early Phase Clinical Trials Network Radiogenomics Database (N=262 from 8 centers; Confirmation); 3) the chemoradiation placebo arm from an international phase III trial (AVAglio; N=394 from 120 locations in 23 countries; Validation); 4) the experimental arm from AVAglio examining chemoradiation plus bevacizumab (N=404 from 120 locations in 23 countries; Exploratory Set 1); and 5) an Alliance (N0874) Phase I/II trial of vorinostat plus chemoradiation (N=53; Exploratory Set 2)...
April 5, 2018: Neuro-oncology
https://www.readbyqxmd.com/read/29651813/contralateral-adrenal-width-predicts-the-duration-of-prolonged-post-surgical-steroid-replacement-for-subclinical-cushing-syndrome
#11
Masahiro Sugiura, Yusuke Imamura, Koji Kawamura, Satoshi Yamamoto, Tomokazu Sazuka, Kazuyoshi Nakamura, Shinichi Sakamoto, Hidekazu Nagano, Hisashi Koide, Tomoaki Tanaka, Takashi Imamoto, Akira Komiya, Tomohiko Ichikawa
OBJECTIVES: To identify pre-treatment factors affecting the duration of post-surgical steroid replacement in patients undergoing adrenalectomy for subclinical Cushing syndrome. METHODS: The present retrospective analysis included 64 patients who underwent unilateral laparoscopic adrenalectomy for subclinical Cushing syndrome. Adrenal tumor and contralateral adrenal sizes together with various clinical factors were studied in association with the duration of post-surgical steroid replacement...
April 12, 2018: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/29651419/management-of-glioblastoma-multiforme-in-a-patient-treated-with-ketogenic-metabolic-therapy-and-modified-standard-of-care-a-24-month-follow-up
#12
Ahmed M A Elsakka, Mohamed Abdel Bary, Eman Abdelzaher, Mostafa Elnaggar, Miriam Kalamian, Purna Mukherjee, Thomas N Seyfried
Few advances have been made in overall survival for glioblastoma multiforme (GBM) in more than 40 years. Here, we report the case of a 38-year-old man who presented with chronic headache, nausea, and vomiting accompanied by left partial motor seizures and upper left limb weakness. Enhanced brain magnetic resonance imaging revealed a solid cystic lesion in the right partial space suggesting GBM. Serum testing revealed vitamin D deficiency and elevated levels of insulin and triglycerides. Prior to subtotal tumor resection and standard of care (SOC), the patient conducted a 72-h water-only fast...
2018: Frontiers in Nutrition
https://www.readbyqxmd.com/read/29643149/involvement-of-prokineticin-2-expressing-neutrophil-infiltration-in-5-fluorouracil-induced-aggravation-of-breast-cancer-metastasis-to-lung
#13
Soichiro Sasaki, Tomohisa Baba, Hayato Muranaka, Yamato Tanabe, Chiaki Takahashi, Seiichi Matsugo, Naofumi Mukaida
Adjuvant chemotherapy is used for human breast cancer patients, even after curative surgery of primary tumor, in order to prevent tumor recurrence primarily as a form of metastasis. However, anti-cancer drugs can accelerate metastasis in several mouse metastasis models. Hence, we examined the effects of post-surgical administration with 5-fluorouracil (5-FU), doxorubicin, and cyclophosphamide, on lung metastasis process, which developed after the resection of the primary tumor arising from the orthotopic injection of a mouse triple-negative breast cancer cell line, 4T1...
April 11, 2018: Molecular Cancer Therapeutics
https://www.readbyqxmd.com/read/29627368/supportive-topical-tranexamic-acid-application-for-hemostasis-in-oral-bleeding-events-retrospective-cohort-study-of-542-patients
#14
Matthias Zirk, Max Zinser, Johannes Buller, Viktor Bilinsky, Timo Dreiseidler, Joachim E Zöller, Matthias Kreppel
PURPOSE: Tranexamic acid (TXA) is widely used in the prevention of postsurgical oral bleeding. Tranexamic acid in addition to further surgical measures is widely utilized in prevention of post-surgical oral bleeding. The aim of the present study was to investigate: Can oral hemostasis be achieved by merely compression and topical application of tranexamic acid in different anticoagulant regimes among patients attending a general emergency department? Where are the limits to this procedure? Which has the greater impact on surgeons' choice for an invasive hemostatic approach-bleeding quality or oral anticoagulant therapy? MATERIALS AND METHODS: A retrospective cohort study of 542 patients who consecutively received treatment for oral bleeding was performed...
March 20, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29626695/multi-functional-electrospun-antibacterial-core-shell-nanofibrous-membranes-for-prolonged-prevention-of-post-surgical-tendon-adhesion-and-inflammation
#15
K T Shalumon, Chialin Sheu, Chih-Hao Chen, Shih-Heng Chen, Gils Jose, Chang-Yi Kuo, Jyh-Ping Chen
The possibility of endowing an electrospun anti-adhesive barrier membrane with multi-functionality, such as lubrication, prevention of fibroblast attachment and anti-infection and anti-inflammation properties, is highly desirable for the management of post-surgical tendon adhesion. To this end, we fabricated core-shell nanofibrous membranes (CSNMs) with embedded silver nanoparticles (Ag NPs) in the poly(ethylene glycol) (PEG)/poly(caprolactone) (PCL) shell and hyaluronic acid (HA)/ibuprofen in the core. HA imparted a lubrication effect for smooth tendon gliding and reduced fibroblast attachment, while Ag NPs and ibuprofen functioned as anti-infection and anti-inflammation agents, respectively...
April 4, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29626286/multidetector-ct-of-expected-findings-and-complications-after-hysterectomy
#16
REVIEW
Massimo Tonolini
Indicated to manage a variety of disorders affecting the female genital tract, hysterectomy represents the second most common gynaecological operation after caesarean section. Performed via an open, laparoscopic or vaginal approach, hysterectomy is associated with non-negligible morbidity and occasional mortality. Iatrogenic complications represent a growing concern for gynaecologists and may result in prolonged hospitalisation, need for interventional procedures or repeated surgery, renal impairment and malpractice claims...
April 6, 2018: Insights Into Imaging
https://www.readbyqxmd.com/read/29626122/age-specific-18-f-fdg-image-processing-pipelines-and-analysis-are-essential-for-individual-mapping-of-seizure-foci-in-paediatric-patients-with-intractable-epilepsy
#17
Bianca De Blasi, Anna Barnes, Ilaria Boscolo Galazzo, Chia-Ho Hua, Barry Shulkin, Matthias Koepp, Martin Tisdall
Fluoro-18-deoxyglucose positron emission tomography (FDG-PET) is an important tool for the pre-surgical assessment of children with drug-resistant epilepsy. Standard assessment is carried out visually and this is often subjective and highly user-dependent. Voxel-wise statistics can be used to remove user-dependent biases by automatically identifying areas of significant hypo/hyper-metabolism, associated to the epileptogenic area. In the clinical settings, this analysis is carried out using commercially available software...
April 6, 2018: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29625278/right-atrial-dual-loop-reentry-tachycardia-after-cardiac-surgery-prevalence-electrophysiologic-characteristics-and-ablation-outcomes
#18
Jian-du Yang, Qi Sun, Xiao-Gang Guo, Gong-Bu Zhou, Xu Liu, Bin Luo, Hui-Qiang Wei, Pasquale Santangeli, Jackson J Liang, Jian Ma
BACKGROUND: Right atrial dual-loop reentry tachycardia has been described in patients with open-heart surgery. However, the prevalence, electrophysiologic substrate and ablation outcomes have been poorly characterized. OBJECTIVE: We aimed to investigate the prevalence, electrophysiologic substrate and ablation outcomes for RA dual-loop reentry tachycardia following cardiac surgery. METHODS: We identified all patients with atrial tachycardia after cardiac surgery...
April 3, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29623735/reducing-the-risk-of-post-surgical-cancer-recurrence-a-perioperative-anti-inflammatory-anti-stress-approach
#19
Rita Haldar, Shamgar Ben-Eliyahu
No abstract text is available yet for this article.
April 6, 2018: Future Oncology
https://www.readbyqxmd.com/read/29623492/therapy-for-crohn-s-disease-a-review-of-recent-developments
#20
REVIEW
Gregory J Eustace, Gil Y Melmed
PURPOSE OF REVIEW: To review recent advances in the treatment of Crohn's disease. RECENT FINDINGS: Several key advances are highlighted, including the increasing role of treatment algorithms and where new therapies can be used most effectively, the appropriate use of therapeutic drug monitoring, optimal management of post-surgical patients, and the role of multi-disciplinary clinics. The last several years have seen a number of exciting developments in the field of Crohn's therapy...
April 5, 2018: Current Gastroenterology Reports
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