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https://www.readbyqxmd.com/read/29034014/improving-the-outcome-of-vein-grafts-should-vascular-surgeons-turn-veins-into-arteries
#1
REVIEW
Toshihiko Isaji, Takuya Hashimoto, Kota Yamamoto, Jeans M Santana, Bogdan Yatsula, Haidi Hu, Hualong Bai, Guo Jianming, Tambudzai Kudze, Toshiya Nishibe, Alan Dardik
Autogenous vein grafts remain the gold standard conduit for arterial bypass, particularly for the treatment of critical limb ischemia. Vein graft adaptation to the arterial environment, i.e., adequate dilation and wall thickening, contributes to the superior performance of vein grafts. However, abnormal venous wall remodeling with excessive neointimal hyperplasia commonly causes vein graft failure. Since the PREVENT trials failed to improve vein graft outcomes, new strategies focus on the adaptive response of the venous endothelial cells to the post-surgical arterial environment...
March 24, 2017: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/29033263/-persistent-extra-axial-post-surgical-collections-and-propionibacterium-acnes-infection-presentation-of-two-cases-and-literature-review
#2
Pedro González, José Thenier, Raúl Galárraga, Adolfo de la Lama, Eva Azevedo, Cesáreo Conde
OBJECTIVES: It is common to observe the persistence of extra-axial collections after craniotomies. Most of these disappear in weeks or months but some remain. The onset of focal symptoms or the growth of these persistent collections months or years after surgery may indicate the presence of a chronic and latent infection by germs of low virulence such as Propionibacterium acnes (P. acnes). METHODS: We present two clinical cases with persistent extra-axial collections, which required surgery years after diagnosis, in which P...
October 13, 2017: Neurocirugía
https://www.readbyqxmd.com/read/29032007/the-effect-of-sevoflurane-compared-to-propofol-maintenance-on-post-surgical-quality-of-recovery-in-patients-undergoing-an-ambulatory-gynecological-surgery-a-prospective-randomized-double-blinded-controlled-clinical-trial
#3
Gildasio S De Oliveira, Jane Bialek, Meghan E Rodes, Mark C Kendall, Robert J McCarthy
OBJECTIVE: The main objective of the current investigation was to evaluate the effect of propofol used as anesthetic maintenance compared to sevoflurane on global post-surgical quality of recovery in female patients undergoing ambulatory gynecological surgery. DESIGN: The study was a prospective randomized double blinded, controlled, clinical trial. INTERVENTIONS: Healthy female subjects were randomized to receive propofol or sevoflurane as anesthetic maintenance...
October 12, 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/29030656/-pyoderma-gangraenosum-after-implantation-of-a-shoulder-endoprothesis
#4
M A Domej, L Pauzenberger, P R Heuberer, W Anderl
Pyoderma gangrenosum is an inflammatory, ulcerative, neutrophilic dermatosis that is clinically characterized by rapidly evolving, painful, necrotic skin lesions. It is typically associated with chronic systemic inflammatory or neoplastic diseases, but may also occur secondary to cutaneous injury or surgery (pathergy). Post-surgical pyoderma gangrenosum typically develops around surgical sites within the immediate postoperative period, mimicking early wound infection. However, common treatment strategies including antibiotics and debridement fail to improve or even worsen symptoms...
October 13, 2017: Der Orthopäde
https://www.readbyqxmd.com/read/29029500/edg2-enhanced-the-progression-of-hepatocellular-carcinoma-by-lpa-pi3k-akt-mtor-signaling
#5
Meng Xu, Zhikui Liu, Cong Wang, Bowen Yao, Xin Zheng
HCC is the leading type of the malignant liver tumors with the unsatisfied prognosis. Liver resection has been considered as the predominant curative therapy, however, the post-surgical prognostic evaluation remains an urgent problem and the mechanism of HCC metastases has not been understood completely. EDG2 has been found to accelerate tumor progression through mediating different cell pathways, however, it remains unclear about the role of EDG2 on hepatocarcinogenesis. Here, EDG2 expression was found increased notably in HCC tissues by immunohistochemistry compared with adjacent liver tissues and comparison of survival curves revealed that EDG2 upregulation in HCC tissues was associated with the worse prognosis after liver resection...
September 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/29025607/peek-radiolucent-plate-for-distal-radius-fractures-multicentre-clinical-results-at-12-months-follow-up
#6
Bruno Di Maggio, Pasquale Sessa, Patrizia Mantelli, Pietro Maniscalco, Fabrizio Rivera, Giorgio Maria Calori, Luigi Bisogno, Gabriele Scaravilli, Marco Caforio
INTRODUCTION: Open reduction and internal fixation (ORIF) with plate and screws represents the recommended treatment for unstable intra-articular distal radius fractures. Although significant progresses in surgical technique have been made, anatomical reconstruction of radio-carpal articular surface still represent a difficult task, especially in multifragmentary fractures. Available PEEK reinforced-carbon fiber composite radiolucent devices allow both an easier and more careful assessment of intra-operative reduction of the articular surface of distal radius and prompt correction of any residual step deformity...
October 2017: Injury
https://www.readbyqxmd.com/read/29024614/staphylococcus-aureus-infections-in-german-patients-with-type-2-diabetes-mellitus-after-orthopedic-surgery-incidence-risk-factors-and-clinical-and-health-economic-outcomes
#7
Fraence Gottschalk, Thomas Wilke, Sabrina Mueller, Kirstin Heinrich, Ulf Maywald, Andreas Fuchs, Holly Yu
BACKGROUND: This study assessed Staphylococcus aureus infection risk in patients with type 2 diabetes mellitus (T2DM) undergoing an orthopedic knee, hip, or spine surgery. PATIENTS AND METHODS: All patients with a diagnosis of T2DM in the period from 2010 to 2012 were identified from a German claims database. First inpatient knee, hip, or spine surgery was used as index date. Cumulative incidence of S. aureus infections was calculated for several time intervals...
October 12, 2017: Surgical Infections
https://www.readbyqxmd.com/read/29022090/radiologic-evaluation-of-patients-undergoing-the-modified-appleby-procedure-for-locally-advanced-pancreatic-neoplasms-a-case-series
#8
Merel A T Vergauwen, Michele Perillo, Alejandro Garces-Descovich, Courtney E Barrows, A James Moser, Koenraad J Mortelé
PURPOSE: Despite advances in medical and surgical care, pancreatic ductal adenocarcinoma remains one of the most locally aggressive neoplastic processes in the abdomen. Unfortunately, most pancreatic adenocarcinomas present late and are unresectable at time of diagnosis. The modified Appleby procedure is a surgical option in patients with locally advanced pancreatic neoplasms of the body and tail with vascular invasion of the celiac trunk. To our knowledge, no radiologic journal has previously reported on the pre-operative evaluation or postoperative imaging findings of such patients...
October 11, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29020659/3d-gait-analysis-with-and-without-an-orthopedic-walking-boot
#9
H Gulgin, K Hall, A Luzadre, E Kayfish
INTRODUCTION: Orthopedic walking boots have been widely used in place of traditional fiberglass casts for a variety of orthopedic injuries and post-surgical interventions. These walking boots create a leg length discrepancy (LLD). LLD has been shown to alter the kinematics and kinetics of gait and are associated with lumbar and lower limb conditions such as: foot over pronation, low back pain, scoliosis, and osteoarthritis of the hip and knee joints. Past gait analyses research with orthopedic boots is limited to findings on the ipsilateral limb...
October 5, 2017: Gait & Posture
https://www.readbyqxmd.com/read/29019805/do-obese-and-extremely-obese-patients-lose-weight-after-lumbar-spine-fusions-analysis-of-a-cohort-of-7303-patients-from-the-kaiser-national-spine-registry
#10
Paul T Akins, Maria Cs Inacio, Johannas A Bernbeck, Jessica Harris, Yuexin X Chen, Heather A Prentice, Kern H Guppy
STUDY DESIGN: A retrospective cohort study from the Kaiser Permanente Spine Registry OBJECTIVE.: Determine whether obese and extremely obese patients with lumbar spine fusions lost a clinically significant amount of weight (> 5%) 1 year after their surgery SUMMARY OF BACKGROUND DATA.: Obesity in the United States has a prevalence of 35% and is a global health issue. Obesity is associated with lumbar spine disease. There is limited evidence regarding post-surgical weight loss after spine surgery...
October 10, 2017: Spine
https://www.readbyqxmd.com/read/29017511/mechanical-wrist-traction-as-a-non-invasive-treatment-for-carpal-tunnel-syndrome-a-randomized-controlled-trial
#11
Margreet Meems, Viola Spek, Willem J Kop, Berend-Jan Meems, Leo H Visser, Victor J M Pop
BACKGROUND: Carpal tunnel syndrome (CTS) is a common, compressive nerve-entrapment disorder with symptoms of numbness, paresthesia, and pain. Carpal tunnel release surgery is the only known long-term effective treatment. However, surgery is invasive and up to 30% of patients report recurrence or persistence of symptoms or suffer from post-surgical complications. A promising non-surgical treatment for CTS is mechanical wrist traction. The purpose of this study was to evaluate clinical outcomes following mechanical traction in patients with CTS compared to care as usual...
October 10, 2017: Trials
https://www.readbyqxmd.com/read/29016682/effects-of-mandibular-setback-with-or-without-maxillary-advancement-osteotomies-on-pharyngeal-airways-an-overview-of-systematic-reviews
#12
Su Keng Tan, Wai Keung Leung, Alexander Tin Hong Tang, Roger A Zwahlen
BACKGROUND: Mandibular setback osteotomies potentially lead to narrowing of the pharyngeal airways, subsequently resulting in post-surgical obstructive sleep apnea (OSA). OBJECTIVE: To summarize current evidence from systematic reviews that has evaluated pharyngeal airway changes after mandibular setback with or without concomitant upper jaw osteotomies. METHODOLOGY: PubMed, EMBASE, Web of Science, and Cochrane Library databases were searched with no restriction of language or date...
2017: PloS One
https://www.readbyqxmd.com/read/28994339/intranasal-drug-delivery-devices-and-interventions-associated-with-post-operative-endoscopic-sinus-surgery
#13
Lari K Dkhar, Jim Bartley, David White, Ali Seyfoddin
This review article highlights the importance and advantages of the drug delivery systems applied via the nasal route after endoscopic sinus surgery (ESS) for patients suffering from chronic rhinosinusitis. After ESS, patients often require ongoing topical and systemic medication. To reduce the incidence of immediate and delayed post-surgical complications, a variety of temporary postoperative nasal interventions are currently used. However, newly developed intranasal drug delivery devices can enhance tissue recovery after endoscopic sinus surgery by releasing therapeutic drugs locally, while providing structural support to reduce tissue adhesion and scaring...
October 10, 2017: Pharmaceutical Development and Technology
https://www.readbyqxmd.com/read/28992642/endoscopic-drainage-of-an-infected-post-surgical-abdominal-fluid-collection-using-a-lumen-apposing-metal-stent
#14
Arvind J Trindade, Yonatan J Hillman, John H Wang, Petros C Benias, Larry S Miller
No abstract text is available yet for this article.
October 9, 2017: Endoscopy
https://www.readbyqxmd.com/read/28989922/port-site-infiltration-of-local-anesthetic-after-laparoendoscopic-single-site-surgery-for-benign-adnexal-disease
#15
Jung Eun Kim, Seung-Hyuk Shim, Meari Dong, Hyojin Lee, Han Sung Hwang, Han Sung Kwon, Sun Joo Lee, Ji Young Lee, In Sook Sohn, Soo-Nyung Kim, Soon-Beom Kang
OBJECTIVE: To determine whether local bupivacaine injection into the incision site after gynecologic laparoendoscopic single site surgery (LESS) improves postoperative pain. METHODS: This prospective cohort study included consecutive 158 patients who had LESS for benign adnexal disease from March 2013 to December 2015. Chronologically, 82 patients (March 2013 to August 2014) received no bupivacaine (group 1) and 76 (August 2014 to December 2015) received a bupivacaine block (group 2)...
September 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28989237/lipofilling-effects-after-breast-cancer-surgery-in-post-radiation-patients-an-analysis-of-results-and-algorithm-proposal
#16
Manuel Debald, Thomas Pech, Christina Kaiser, Mignon-Denise Keyver-Paik, Gisela Walgenbach-Bruenagel, Joerg C Kalff, Walther Kuhn, Klaus J Walgenbach
BACKGROUND: Lipofilling or autologous fat transfer is an established technique in plastic surgery. Herein, we describe the lipofilling effects after implant-based breast reconstruction in post-radiation patients and propose an algorithm for indication of lipofilling. METHODS: Forty patients with a history of breast cancer were included in this retrospective analysis. Patients had undergone either breast conserving therapy or mastectomy. Twenty-six patients underwent additional radiation therapy...
2017: European Journal of Plastic Surgery
https://www.readbyqxmd.com/read/28986156/technological-aided-assessment-of-the-acutely-ill-patient-the-case-of-postoperative-complications
#17
C Haahr-Raunkjær, C S Meyhoff, H B D Sørensen, R M Olsen, E K Aasvang
Surgical interventions come with complications and highly reported mortality after major surgery. The mortality may be a result of delayed detection of severe complications due to lower monitoring frequency in the general wards. Several studies have shown that continuous monitoring is superior to the manually intermittent recorded monitoring in terms of detecting abnormal physiological signs. Hopefully improved observations may result in earlier detection and clinical intervention. This narrative review will describe current monitoring possibilities for postoperative patients and how it may prevent complications...
October 3, 2017: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/28984263/evisceration-of-gut-through-post-surgical-drain-site-in-a-neonate
#18
Pradyumna Pan, Rajnish Nema
No abstract text is available yet for this article.
September 15, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/28984096/preventative-effect-of-ketamine-on-post-surgical-hyperalgesia-induced-at-a-body-part-remote-from-the-surgical-site-a-randomized-controlled-trial
#19
Young-Eun Moon, Mi-Hyun Kim, Hyung-Mook Lee, Hyo-Min Yoon, Young-Jae Jeon
BACKGROUND: It is known that pain hypersensitivity can be induced at a body part remote from a surgical site (tertiary hyperalgesia), leading to patient discomfort. Nevertheless, no reported study to date has investigated methods to attenuate such tertiary hyperalgesia. Ketamine is known to modulate hyperalgesia induced by central sensitization. Thus, we investigated whether intraoperative administration of ketamine could decrease post-surgical tertiary hyperalgesia in patients undergoing a laparoscopic hysterectomy...
October 4, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/28974047/heparin-mimetics-their-therapeutic-potential
#20
REVIEW
Shifaza Mohamed, Deirdre R Coombe
Heparin mimetics are synthetic and semi-synthetic compounds that are highly sulfated, structurally distinct analogues of glycosaminoglycans. These mimetics are often rationally designed to increase potency and binding selectivity towards specific proteins involved in disease manifestations. Some of the major therapeutic arenas towards which heparin mimetics are targeted include: coagulation and thrombosis, cancers, and inflammatory diseases. Although Fondaparinux, a rationally designed heparin mimetic, is now approved for prophylaxis and treatment of venous thromboembolism, the search for novel anticoagulant heparin mimetics with increased affinity and fewer side effects remains a subject of research...
October 2, 2017: Pharmaceuticals
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