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Osteoporosis older adults

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https://www.readbyqxmd.com/read/28976598/soluble-inflammatory-markers-and-risk-of-incident-fractures-in-older-adults-the-cardiovascular-health-study
#1
Danijela Stojanović, Petra Bůžková, Kenneth J Mukamal, Susan R Heckbert, Bruce M Psaty, Howard A Fink, Jane A Cauley, Erin Wallace, Lesley H Curtis, Calvin Hirsch, Matthew Budoff, Dong Li, Rebekah Young, Diana Jalal, Joseph A C Delaney
Several in vitro and animal studies have showed that inflammatory markers play a role in bone remodeling and pathogenesis of osteoporosis. Additionally, some human longitudinal studies showed suggestive associations between elevated inflammatory markers and increased risk of non-traumatic fractures. We examined several inflammatory markers and multiple fracture types in a single study of older individuals with extensive follow-up. We assessed the association of four inflammatory markers with the risk of incident hip fractures among 5,265 participants of the Cardiovascular Health Study (CHS) and a composite endpoint of incident fractures of the hip, pelvis, humerus, or proximal forearm in 4,477 participants...
October 4, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28974906/alzheimer-s-disease-and-osteoporosis
#2
REVIEW
Yu-Hung Chen, Raymond Y Lo
Alzheimer's disease (AD) and osteoporosis are both common degenerative diseases in the elderly population. The incidence of both diseases increases with age and will be posing enormous societal burden worldwide. It may appear that AD and osteoporosis are two distinct diseases although many risk factors are shared. Previous observational studies have shown that patients with osteoporosis have higher risks of developing AD than those who do not have osteoporosis. Although osteoporosis, falls, and fractures are more often seen in patients with AD than other older adults, the association between these two diseases may be due to a pathophysiological link rather than one condition causing the other...
July 2017: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/28951404/prevalence-of-and-factors-associated-with-adopting-bone-health-promoting-behaviours-among-people-with-osteoporosis-in-taiwan-a-cross-sectional-study
#3
Po-Han Chen, Ming-Shyan Lin, Tung-Jung Huang, Mei-Yen Chen
OBJECTIVES: To detect osteopenia, osteoporosis, treatments received and bone health promoting behaviours early among postmenopausal women and elderly men, and to explore the associated factors. DESIGN: A community-based cross-sectional study. SETTINGS: Two rural townships in Yunlin County, Taiwan. PARTICIPANTS: A total of 941 adults including 651 postmenopausal women and 290 elderly men aged >65 years. OUTCOME MEASURES: Bone mineral density was measured using dual-energy X-ray absorptiometry...
September 25, 2017: BMJ Open
https://www.readbyqxmd.com/read/28950817/specific-patient-features-affect-antiepileptic-drug-therapy-decisions-focus-on-gender-age-and-psychiatric-comorbidities
#4
Pisani Laura Rosa, Nikanorova Marina, Johannessen Landmark Cecilie, Johannessen Svein Ivor, Pisani Francesco
BACKGROUND: Patient features, apart from the type of seizues/epilepsy, affect markedly antiepileptic drug (AED) choice and dosage. The present review focuses on gender, age and psychiatric comorbidities which play a leading role in influencing antiepileptic treatment. METHODS: Reviews with large population of patients, controlled clinical trials, observational investigations, experimental studies and experimental reviews of experimental data, where appropriated, were analysed and illustrated to produce the most homogeneous indications possible...
September 25, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28936049/prevalence-and-risk-factors-of-dry-eye-symptoms-in-a-saudi-arabian-population
#5
Abdulaziz A Alshamrani, Abdulwahab S Almousa, Abdulrahman A Almulhim, Abdullah A Alafaleq, Mohammed B Alosaimi, Abdulrahman M Alqahtani, Ammar M Almulhem, Mohammed A Alshamrani, Ahmad H Alhallafi, Ismail Z Alqahtani, Abdullah A Alshehri
BACKGROUND: The information about dry eye epidemiology in Saudi Arabia is few in literature. PURPOSE: To estimate the prevalence and identify determinants of dry eye symptoms (DES) in Al-Ahsa, Saudi Arabia. METHODS: Using a multi-stage proportionate sampling technique, Saudis of both genders from 6 urban and 4 rural Primary Health Care centers in Al-Ahsa were enrolled. They were interviewed to gather data on sociodemography, symptoms of dry eye, factors potentially related to dry eye, and chronic comorbidities...
April 2017: Middle East African Journal of Ophthalmology
https://www.readbyqxmd.com/read/28933175/-hiv-infection-a-new-disease-of-internal-medicine
#6
Svatava Snopková
Modern antiretroviral treatment belongs to the greatest success of current medicine. HIV infection has gone from a death sentence to a manageable chronic disease which develops several decades. Thanks to treatment advances, people with HIV can and do live long and full lives. In the last two decades, the incidence AIDS defining illnesses have been dramatically reduced especially opportunistic infections and malignancies, whereas the role of non-infection comorbidities has risen than age-matched HIV uninfected adults...
2017: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/28922979/a-review-of-drug-drug-interactions-in-older-hiv-infected-patients
#7
Aarthi Chary, Nancy N Nguyen, Kimberly Maiton, Mark Holodniy
The number of older HIV-infected people is growing due to increasing life expectancies resulting from the use of antiretroviral therapy (ART). Both HIV and aging increase the risk of other comorbidities, such as cardiovascular disease, osteoporosis, and some malignancies, leading to greater challenges in managing HIV with other conditions. This results in complex medication regimens with the potential for significant drug-drug interactions and increased morbidity and mortality. Area covered: We review the metabolic pathways of ART and other medications used to treat medical co-morbidities, highlight potential areas of concern for drug-drug interactions, and where feasible, suggest alternative approaches for treating these conditions as suggested from national guidelines or articles published in the English language...
September 19, 2017: Expert Review of Clinical Pharmacology
https://www.readbyqxmd.com/read/28865232/hyponatremia-bone-mineral-density-and-falls-in-the-elderly-results-from-ahap-study
#8
Seyed Reza Hosseini, Naghi Baghitabar, Ali Mirzapour, Farshid Oliaei, Hajighorban Nooreddini, Ali Bijani, Simin Mouodi
BACKGROUND: Hyponatremia (HN) can be associated with osteoporosis, falls and bone fractures in the elderly. Recent researches demonstrated different results about the correlation of HN with bone mineral density and bone fractures. METHODS: This analytic research came from the AHAP project in northern IRAN. All people aged 60 years and over were included in the study. Individuals with severe comorbidities and them who had concurrent conditions which could have impact on bone mineral densities (BMD) such as long-term use of steroids, calcium and/or vitamin D supplements, bisphosphonates, calcitonin, thiazides and hormonal medications were excluded...
August 28, 2017: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/28821868/dysmobility-syndrome-and-risk-of-mortality-for-community-dwelling-middle-aged-and-older-adults-the-nexus-of-aging-and-body-composition
#9
Wei-Ju Lee, Li-Kuo Liu, An-Chun Hwang, Li-Ning Peng, Ming-Hsien Lin, Liang-Kung Chen
Dysmobility syndrome is a newly proposed concept to comprehensively consider bone-muscle-adiposity as a whole to associate with mortality and other adverse outcomes in the older adults. Little was known in Asian populations since the body composition was highly related to ethnicity. The study aimed to evaluate the association between dysmobility syndrome and mortality and to explore the most optimal operational definition for dysmobility syndrome. The prevalence of dysmobility syndrome was 3.9-10.1% based on different operational definitions of adiposity and skeletal muscle index...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28800292/osteoporosis-knowledge-translation-for-young-adults-new-directions-for-prevention-programs
#10
Alyson Holland
INTRODUCTION: Osteoporosis prevention is heavily reliant on education programs, which are most effective when tailored to their intended audience. Most osteoporosis prevention education is designed for older adults, making application of these programs to younger adults difficult. Designing programs for young adults requires understanding the information-seeking practices of young adults, so that knowledge about osteoporosis can be effectively translated. METHODS: Individual interviews were conducted with 60 men and women-multiethnic, Canadian young adults-to explore both the sources and types of information they search for when seeking information on nutrition or bone health...
August 2017: Health Promotion and Chronic Disease Prevention in Canada
https://www.readbyqxmd.com/read/28796598/prevalence-correlates-and-time-trends-of-multiple-chronic-conditions-among-israeli-adults-estimates-from-the-israeli-national-health-interview-survey-2014-2015
#11
Samah Hayek, Anneke Ifrah, Teena Enav, Tamy Shohat
INTRODUCTION: Chronic diseases constitute a major public health challenge. The prevalence of multiple chronic conditions (MCC) has increased. The objective of our study was to describe the prevalence, correlates, and time trends of MCC in the Israeli population and among the nation's 2 main population groups (Jewish and Arab). METHODS: To describe the prevalence of correlates of MCC, we used data from the 2014-2015 Israeli National Health Interview Survey-III (INHIS-III)...
August 10, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/28746019/evaluation-of-a-just-in-time-nurse-consultation-on-bone-health-a-pilot-randomized-controlled-trial
#12
Douglas W Roblin, David Zelman, Sally Plummer, Brandi E Robinson, Yiyue Lou, Stephanie W Edmonds, Fredric D Wolinsky, Kenneth G Saag, Peter Cram
CONTEXT: Evidence is inconclusive whether a nurse consultation can improve osteoporosis-related patient outcomes. OBJECTIVE: To evaluate whether a nurse consultation immediately after dual-energy x-ray absorptiometry (DXA) produced better osteoporosis-related outcomes than a simple intervention to activate adults in good bone health practices or usual care. DESIGN: Pilot randomized controlled trial, conducted within the larger Patient Activation After DXA Result Notification (PAADRN) trial (NCT01507662)...
2017: Permanente Journal
https://www.readbyqxmd.com/read/28700637/contingent-association-between-the-size-of-the-social-support-network-and-osteoporosis-among-korean-elderly-women
#13
Seungwon Lee, Da Hea Seo, Kyoung Min Kim, Eun Young Lee, Hyeon Chang Kim, Chang Oh Kim, Yoosik Youm, Yumie Rhee
OBJECTIVE: To investigate the association between the number of personal ties (or the size of the social support network) and the incidence of osteoporosis among older women in Korea. METHODS: Data from the Korean Urban Rural Elderly Study were used. Bone density was measured by dual-energy X-ray absorptiometry at the lumbar spine (L1-L4) and femur neck. T-score, the standardized bone density compared with what is normally expected in a healthy young adult, was measured and the presence of osteoporosis was determined, if the T-score was < -2...
2017: PloS One
https://www.readbyqxmd.com/read/28687055/psychometric-properties-of-the-swedish-version-of-the-falls-efficacy-scale-international-for-older-adults-with-osteoporosis-self-reported-balance-deficits-and-fear-of-falling
#14
Alexandra Halvarsson, Agneta Ståhle
PURPOSE: Investigate the psychometric properties of the Swedish version of the Falls Efficacy Scale-International (FES-I). METHOD: Cross-sectional study. Community-dwelling older adults with self-reported balance deficits and fear of falling were recruited from an ongoing randomised controlled study to evaluate the psychometric properties of the FES-I using Rasch model analysis. RESULTS: The Rasch model analysis revealed good category function, the questionnaire measured one dimension with an explained variance of 68...
July 7, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28686536/dietary-protein-intake-above-the-current-rda-and-bone-health-a-systematic-review-and-meta-analysis
#15
Taylor C Wallace, Cara L Frankenfeld
Dietary intake of protein is fundamental for optimal acquisition and maintenance of bone across all life stages; however, it has been hypothesized that intakes above the current recommended dietary allowance (RDA) might be beneficial for bone health. We utilized the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines when preparing and reporting this systematic review and meta-analysis. A literature search strategy through April 11, 2017, was developed for the following 3 databases: PubMed, Ovid Medline, and Agricola...
August 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28685282/bone-mineral-density-in-adults-with-down-syndrome
#16
A Carfì, R Liperoti, D Fusco, S Giovannini, V Brandi, D L Vetrano, E Meloni, D Mascia, E R Villani, E Manes Gravina, R Bernabei, G Onder
This study analyzed data of bone mineral density (BMD) from a large cohort of adults with Down syndrome (DS). BMD was found to decrease with age more rapidly in these subjects than in the general population, exposing adults with DS to an increased risk of osteoporosis and bone fracture. INTRODUCTION: Down syndrome (DS) in adulthood presents with a high prevalence of osteoporosis. However, in DS, bone mineral density (BMD) can be underestimated due to short stature. Furthermore, the rate of age-related decline in BMD and its association with gender in DS has been rarely evaluated or compared with the general population...
July 6, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28671443/subclinical-hyperthyroidism-when-to-consider-treatment
#17
REVIEW
Ines Donangelo, Se Young Suh
Subclinical hyperthyroidism is defined by a low or undetectable serum thyroid-stimulating hormone level, with normal free thyroxine and total or free triiodothyronine levels. It can be caused by increased endogenous production of thyroid hormone (e.g., in Graves disease, toxic nodular goiter, or transient thyroiditis), by administration of thyroid hormone to treat malignant thyroid disease, or by unintentional excessive replacement therapy. The prevalence of subclinical hyperthyroidism in the general population is about 1% to 2%; however, it may be higher in iodinedeficient areas...
June 1, 2017: American Family Physician
https://www.readbyqxmd.com/read/28661865/health-benefits-of-tai-chi-what-is-the-evidence
#18
REVIEW
Patricia Huston, Bruce McFarlane
OBJECTIVE: To summarize the evidence on the health benefits of tai chi. SOURCES OF INFORMATION: A literature review was conducted on the benefits of tai chi for 25 specific conditions, as well as for general health and fitness, to update a 2014 review of systematic reviews. Systematic reviews and recent clinical trials were assessed and organized into 5 different groups: evidence of benefit as excellent, good, fair, or preliminary, or evidence of no direct benefit...
November 2016: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28651923/randomized-controlled-trials-covering-pharmaceutical-care-and-medicines-management-a-systematic-review-of-literature
#19
REVIEW
Zaheer-Ud-Din Babar, Rozina Kousar, Ghulam Murtaza, Saira Azhar, Shujaat Ali Khan, Louise Curley
OBJECTIVE: To review the effects of pharmaceutical care on hospitalizations, mortality and clinical outcomes in patients. METHODS: Systematic searches were conducted in MEDLINE, EMBASE and International Pharmaceutical Abstracts (IPA) databases to identify studies that were published between 2004 and January 2017. Studies included in this review were randomized controlled trials (RCTs) that spanned across both community and hospital settings. Using strict inclusion/exclusion criteria studies were included if they reported level 1 or 2 outcomes in the hierarchy of outcome measure i...
June 19, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28645976/a-combined-randomised-and-observational-study-of-surgery-for-fractures-in-the-distal-radius-in-the-elderly-crossfire-a-study-protocol
#20
Ian A Harris, Justine M Naylor, Andrew Lawson, Rachelle Buchbinder, Rebecca Ivers, Zsolt Balogh, Paul Smith, Rajat Mittal, Wei Xuan, Kirsten Howard, Arezoo Vafa, Piers Yates, Bertram Rieger, Geoff Smith, Ilia Elkinson, Woosung Kim, Mellick Chehade, Jai Sungaran, Kim Latendresse, James Wong, Sameer Viswanathan, Martin Richardson, Kush Shrestha, Herwig Drobetz, Phong Tran, Jeremy Loveridge, Richard Page, Raphael Hau, Roger Bingham, Jonathan Mulford, Ian Incoll
Fractures of the distal radius are common and occur in all age groups. The incidence is high in older populations due to osteoporosis and increased falls risk. Considerable practice variation exists in the management of distal radius fractures in older patients ranging from closed reduction with cast immobilisation to open reduction with plate fixation. Plating is currently the most common surgical treatment. While there is evidence showing no significant advantage for some forms of surgical fixation over conservative treatment, and no difference between different surgical techniques, there is a lack of evidence comparing two of the most common treatments used: closed reduction and casting versus plating...
June 23, 2017: BMJ Open
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