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https://www.readbyqxmd.com/read/28524027/-effect-of-chest-physiotherapy-in-patients-undergoing-mechanical-ventilation-a-prospective-randomized-controlled-trial
#1
Hui Zeng, Zhen Zhang, Yuan Gong, Miao Chen
OBJECTIVE: To investigate the effect of chest physiotherapy (CPT) on patients undergoing mechanical ventilation (MV). METHODS: A prospective randomized controlled trial (RCT) was conducted. Sixty-eight adult patients undergoing invasive MV over 48 hours admitted to intensive care unit (ICU) of Affiliated Hospital of Zunyi Medical College from December 2014 to October 2016 were enrolled, and they were divided into CPT group (n = 37) and control group (n = 31) by random number table...
May 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28348805/a-cardiac-implantable-device-infection-by-raoultella-planticola-in-an-immunocompromized-patient
#2
Chandra Adjodah, Chistophe D'Ivernois, David Leyssene, Jean-Baptiste Berneau, Yann Hemery
Introduction. Infection of cardiac implantable electronic devices is a severe condition associated with high mortality, particularly in patients who are dependent upon heart-pacing devices. Staphylococci are found in 70 % of reported cases. Case presentation. We report the case of a cardiac-pacemaker infection in a 79-year-old man, cumulating a history of rheumatoid arthritis treated by corticosteroids and methotrexate by a recently identified micro-organism: Raoultella planticola. He presented local signs of infection on his VVI pacemaker implantation site and underwent urgent pocket device replacement under cefamandole antibioprophylaxis...
February 2017: JMM Case Reports
https://www.readbyqxmd.com/read/28263857/organ-donation-an-unexpected-benefit-of-aggressive-resuscitation-of-trauma-patients-presenting-dead-on-arrival
#3
Abdul Q Alarhayem, Stephen M Cohn, Mark T Muir, John G Myers, James Fuqua, Brian J Eastridge
BACKGROUND: We sought to determine whether aggressive resuscitation in trauma patients presenting without vital signs, or "dead on arrival," was futile. We also sought to determine whether organ donation was an unexpected benefit of aggressive resuscitation. STUDY DESIGN: We conducted a review of adults presenting to our Level I trauma center with no signs of life (pulse = 0 beats/min; systolic blood pressure = 0 mmHg; and no evidence of neurologic activity, Glasgow Coma Scale score = 3)...
May 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28141920/face-transplantation-partial-graft-loss-of-the-first-case-10-years-later
#4
E Morelon, P Petruzzo, J Kanitakis, S Dakpé, O Thaunat, V Dubois, G Choukroun, S Testelin, J-M Dubernard, L Badet, B Devauchelle
Ten years after the first face transplantation, we report the partial loss of this graft. After two episodes of acute rejection (AR) occurred and completely reversed in the first posttransplantation year, at 90 months posttransplantation the patient developed de novo class II donor-specific antibodies, without clinical signs of AR. Some months later, she developed several skin rejection episodes treated with steroid pulses. Despite rapid clinical improvement, some months later the sentinel skin graft underwent necrosis...
July 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28137533/traditional-chinese-medicine-zheng-identification-of-bronchial-asthma-clinical-investigation-of-2500-adult-cases
#5
Zhiwan Wang, Jiansheng Li, Yang Xie, Xueqing Yu, Zhaowang Zhang
OBJECTIVES: This study aims to employ more comprehensive approaches to analyze the primary and secondary symptoms of clinical common TCM ZHENG of bronchial asthma according to the clinical investigation of 2500 adult cases. METTHODS: Patients met the inclusion criteria were surveyed by associate chief physician or chief physician through the TCM Clinical investigation questionnaire containing general demographic information, signs and symptoms, tongue and pulse conditions...
February 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28079811/routine-application-of-lung-ultrasonography-in-the-neonatal-intensive-care-unit
#6
Shui-Wen Chen, Wei Fu, Jing Liu, Yan Wang
The aim of this study was to study the features of lung ultrasonography (LUS) in lung disease and to evaluate the usefulness of LUS in the neonatal intensive care unit (NICU).All of 3405 neonates included in this study underwent an LUS examination. Diagnoses were based on medical history, clinical manifestation, laboratory examination, and signs on chest radiography (CR) and/or computed tomography (CT). A single expert physician performed all LUS examinations.There were 2658 cases (78.9%) with lung disease and 747 cases (21...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27982272/cardiopulmonary-exercise-test-background-applicability-and-interpretation
#7
REVIEW
Artur Haddad Herdy, Luiz Eduardo Fonteles Ritt, Ricardo Stein, Claudio Gil Soares de Araújo, Mauricio Milani, Romeu Sérgio Meneghelo, Almir Sérgio Ferraz, Carlos Hossri, Antonio Eduardo Monteiro de Almeida, Miguel Morita Fernandes-Silva, Salvador Manoel Serra
Cardiopulmonary exercise test (CPET) has been gaining importance as a method of functional assessment in Brazil and worldwide. In its most frequent applications, CPET consists in applying a gradually increasing intensity exercise until exhaustion or until the appearance of limiting symptoms and/or signs. The following parameters are measured: ventilation; oxygen consumption (VO2); carbon dioxide production (VCO2); and the other variables of conventional exercise testing. In addition, in specific situations, pulse oximetry and flow-volume loops during and after exertion are measured...
November 2016: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/27783380/common-pitfalls-in-point-of-care-ultrasound-a-practical-guide-for-emergency-and-critical-care-physicians
#8
REVIEW
Pablo Blanco, Giovanni Volpicelli
BACKGROUND: Point-of-care ultrasonography (POCUS) is a widely used tool in emergency and critical care settings, useful in the decision-making process as well as in interventional guidance. While having an impressive diagnostic accuracy in the hands of highly skilled operators, inexperienced practitioners must be aware of some common misinterpretations that may lead to wrong decisions at the bedside. OBJECTIVES: This article provides a revision list of common POCUS misdiagnoses usually found in practice and offers useful tips to recognize and avoid them...
December 2016: Critical Ultrasound Journal
https://www.readbyqxmd.com/read/27736042/lung-and-cardiac-ultrasound-for-hemodynamic-monitoring-of-patients-with-severe-pre-eclampsia
#9
J Ambrozic, G Brzan Simenc, K Prokselj, N Tul, M Cvijic, M Lucovnik
OBJECTIVE: To evaluate lung and cardiac ultrasound for the assessment of fluid tolerance and fluid responsiveness before and after delivery in pregnant women with severe pre-eclampsia (PE). METHODS: This was a prospective observational study of singleton pregnant women with severe PE and healthy term controls. Lung ultrasound echo comet score (ECS), which denotes the amount of extravascular lung water, was obtained using the 28-rib interspaces technique. The echocardiographic E/e' ratio, measured by pulsed-wave and tissue Doppler, was used as a marker of diastolic left ventricular function...
January 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27355324/n-ethylmaleimide-sensitive-factor-nsf-inhibition-prevents-vascular-instability-following-gram-positive-pulmonary-challenge
#10
Ji Young Lee, Helena M Linge, Kanta Ochani, Ke Lin, Edmund J Miller
BACKGROUND: The Acute Respiratory Distress Syndrome (ARDS), remains a significant source of morbidity and mortality in critically ill patients. Pneumonia and sepsis are leading causes of ARDS, the pathophysiology of which includes increased pulmonary microvascular permeability and hemodynamic instability resulting in organ dysfunction. We hypothesized that N-ethylmaleimide sensitive factor (NSF) regulates exocytosis of inflammatory mediators, such as Angiopoietin-2 (Ang-2), and cytoskeletal stability by modulating myosin light chain (MLC) phosphorylation...
2016: PloS One
https://www.readbyqxmd.com/read/27338785/differences-in-virulence-between-bovine-derived-clinical-isolates-of-pasteurella-multocida-serotype-a-from-the-uk-and-the-usa-in-a-model-of-bovine-pneumonic-pasteurellosis
#11
M P Dagleish, C W Bayne, G G Moon, J Finlayson, J Sales, J Williams, J C Hodgson
The time of onset and subsequent degree and progression of clinical signs, bacterial colonization and tissue pathology during experimental disease induced by intratracheal inoculation of either a UK or USA isolate of Pasteurella multocida serotype A recovered from clinical cases of bovine pneumonia were determined. Calves aged 8 weeks were challenged with 300 ml phosphate buffered saline (PBS) alone (group 1, n = 3, negative control) or containing 7.1 × 10(8) colony forming units (cfu) of UK isolate (group 2, n = 8) or 5...
July 2016: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/26914350/the-first-hand-allotransplantation-in-taiwan-a-report-at-9-months
#12
Yur-Ren Kuo, Chien-Chang Chen, Yen-Chou Chen, Ming-Chung Yeh, Pao-Yuan Lin, Chen-Hsiang Lee, Jui-Kun Chang, Yi-Chun Lin, Shun-Chen Huang, Yuan-Cheng Chiang, Nien-Mu Chiu, Yu Lee, Yu-Chi Huang, Jiun-Lung Liang, Re-Wen Wu, Ka-Kit Siu, Kuan-Chih Chung, Min-Hsien Chiang, Cheng-Chung Pan, Fu-Chan Wei
PURPOSE: Hand transplantations have been initiated and have been encouraged by promising results for more than 1 decade. The aim of this study was to present the first case of hand transplantation performed in Taiwan. MATERIALS AND METHODS: On September 3, 2014, we transplanted the left distal forearm and hand of a brain-dead managed 37 years to a man aged 45 years who had traumatic amputation of the distal third of his right forearm 30 years ago. The total ischemic time during the transplantation was 6 hours and 45 minutes...
February 2016: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/26911940/-experience-of-integrated-traditional-chinese-and-western-medicine-in-first-case-of-imported-zika-virus-disease-in-china
#13
Yichu Deng, Liping Zeng, Wen Bao, Pinghua Xu, Gongrong Zhong
OBJECTIVE: Zika virus disease is an acute infectious disease caused by Zika virus transmitted through Aedes mosquitoes. To explore the therapeutic effect of integrated traditional Chinese and Western Medicine for Zika virus disease, the treatment process of the first imported case in China was reviewed. METHODS: The first imported Zika virus disease in China was admitted to Ganxian People's Hospital in Jiangxi Province on February 6th, 2016, and the patient received isolation treatment for 9 days and cured later...
February 2016: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/26678647/association-of-aortic-stiffness-and-wave-reflections-with-coronary-flow-reserve-in-women-without-obstructive-coronary-artery-disease-an-ancillary-study-from-the-national-heart-lung-and-blood-institute-sponsored-women-s-ischemia-syndrome-evaluation-wise
#14
Wilmer W Nichols, Scott J Denardo, Jonathan B Davidson, Tianyao Huo, C Noel Bairey Merz, Carl J Pepine
BACKGROUND: Increased aortic stiffness and reduced coronary flow reserve (CFR) independently predict adverse outcomes. But information about relationships between arterial properties and CFR in subjects without obstructive coronary artery disease (CAD) is limited. METHODS: CFR was measured (Doppler flow wire and intracoronary adenosine) in 50 women (age 53 ± 11 years) with symptoms and signs of myocardial ischemia without obstructive CAD. Aortic pulse wave velocity (aPWV), a measure of aortic stiffness, was obtained via catheter pullback; radial artery pressure waves were measured by applanation tonometry and central aortic pressure synthesized...
December 2015: American Heart Journal
https://www.readbyqxmd.com/read/26655843/the-effect-of-irreversible-electroporation-on-the-femur-experimental-study-in-a-rabbit-model
#15
Yue Song, Jingjing Zheng, Mingwei Yan, Weidong Ding, Kui Xu, Qingyu Fan, Zhao Li
Irreversible electroporation (IRE) is a novel ablation method that has been tested in humans with lung, prostate, kidney, liver, lymph node and presacral cancers. As a new non-thermal treatment, the use of IRE to ablate tumors in the musculoskeletal system might reduce the incidence of fractures. We aimed to determine the ablation threshold of cortical bone and to evaluate the medium- and long-term healing process and mechanical properties of the femur in a rabbit model post-IRE ablation. The ablation threshold of cortical bone was between 1090 V/cm and 1310 V/cm (120 pulses)...
December 10, 2015: Scientific Reports
https://www.readbyqxmd.com/read/26606984/a-disorder-of-surfactant-metabolism-without-identified-genetic-mutations
#16
Silvia Montella, Timothy J Vece, Claire Langston, Paola Carrera, Lawrence M Nogee, Aaron Hamvas, Angelo Manna, Mariarosaria Cervasio, Mara Cervasio, Francesca Santamaria
BACKGROUND: Surfactant metabolism disorders may result in diffuse lung disease in children. CASE PRESENTATION: We report a 3-years-old boy with dry cough, progressive hypoxemia, dyspnea and bilateral ground glass opacities at chest high-resolution computed tomography (HRCT) who had no variants in genes encoding surfactant proteins or transcription factors. Lung histology strongly suggested an abnormality of surfactant protein. A 7-month course of pulse intravenous high-dose methylprednisolone plus oral hydroxychloroquine and azithromycin led to gradual weaning from oxygen and oral steroids, and to improvement of cough and dyspnea...
2015: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/26257857/the-use-of-lung-ultrasonography-to-confirm-lung-isolation-in-an-infant-who-underwent-emergent-video-assisted-thoracoscopic-surgery-a-case-report
#17
Jae-Sik Nam, Inkyung Park, Hyungseok Seo, Hong-Gi Min
Video-assisted thoracoscopic surgery for pediatric patients has gained popularity due to better outcomes than open surgery. For this procedure, one-lung ventilation may be necessary to provide an adequate surgical field. Confirming lung isolation is crucial when one-lung ventilation is required. Recently, we experienced a case in which one-lung ventilation was confirmed by ultrasonography using the lung sliding sign and the lung pulse in an infant. Since lung ultrasonography can be performed easily and quickly, it may be a useful method to confirm lung isolation, particularly in emergency surgeries with limited time, devices, and experienced anesthesiologists...
August 2015: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/25948635/early-identification-of-asymptomatic-pulmonary-embolism-proximal-to-the-subsegmental-arteries-after-gynecologic-surgery
#18
Masao Okadome, Toshiaki Saito, Kumi Shimamoto, Rihoko Ogahara, Hiromi Akiyoshi, Minoru Fujimoto, Kenji Shinozaki
Few studies have assessed whether cases of asymptomatic pulmonary embolism (PE) in the early postoperative phase are subsegmental versus more proximal. In this study, we investigated whether asymptomatic PE occurring just after gynecologic surgery was subsegmental, and we examined the background characteristics of patients who experienced PE within 2 months postoperatively. All hospital records were reviewed, yielding a total of 2052 women who had undergone surgeries performed by the gynecologic oncology team between 2003 and 2013 in the National Kyushu Cancer Center...
January 2016: Clinical and Applied Thrombosis/hemostasis
https://www.readbyqxmd.com/read/25766350/systemic-lupus-erythematosus-presenting-as-acute-lupus-pneumonitis-in-a-young-female
#19
B Chattopadhyay, A Chatterjee, A Maiti, N B Debnath
Acute lupus pneumonitis is a rare initial presentation of systemic lupus erythematosus (SLE). We report a 19-year-old female presenting with fever and recurrent hemoptysis with radiological evidence of parenchymal lung involvement with mild pleural effusion. Subsequent development of malar and discoid rash with anti-nuclear antibodies (ANA) and anti-dsDNA positivity clinched the diagnosis. Her clinical signs and symptoms resolved with a course of intravenous pulse methyl-prednisolone along with radiological resolution...
April 2015: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/25534190/severe-ebola-virus-disease-with-vascular-leakage-and-multiorgan-failure-treatment-of-a-patient-in-intensive-care
#20
Timo Wolf, Gerrit Kann, Stephan Becker, Christoph Stephan, Hans-Reinhardt Brodt, Philipp de Leuw, Thomas Grünewald, Thomas Vogl, Volkhard A J Kempf, Oliver T Keppler, Kai Zacharowski
BACKGROUND: In the current epidemic of Ebola virus disease in western Africa, many aid workers have become infected. Some of these aid workers have been transferred to specialised hospitals in Europe and the USA for intensified treatment, providing the potential for unique insight into the clinical course of Ebola virus disease under optimised supportive measures in isolation units. METHODS: A 38-year-old male doctor who had contracted an Ebola virus infection in Sierra Leone was airlifted to University Hospital Frankfurt, Germany, on day 5 after disease onset...
April 11, 2015: Lancet
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