keyword
https://read.qxmd.com/read/38474126/the-cd177-c-1291a-allele-leads-to-a-loss-of-membrane-expression-and-mimics-a-cd177-null-phenotype
#1
JOURNAL ARTICLE
Annalena Traum, Stefanie Jehle, Yannick Waxmann, Anne-Sophie Litmeyer, Heike Berghöfer, Gregor Bein, Reinhard Dammann, Alexander Perniss, Monika Burg-Roderfeld, Ulrich J Sachs, Behnaz Bayat
CD177 is a glycosyl phosphatidyl inositol (GPI)-linked, neutrophil-specific glycoprotein that in 3-5% of normal individuals is absent from all neutrophils. The molecular mechanism behind the absence of CD177 has not been unravelled completely. Here, we analyse the impact of the recently described CD177 c.1291G>A variant on CD177 expression. Recombinant CD177 c.1291G>A was expressed in HEK293F cells and its expression on the cell surface, inside the cell, and in the culture supernatant was investigated...
March 1, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38337536/topical-treatment-is-effective-and-safe-for-acute-ankle-sprains-the-multi-center-double-blind-randomized-placebo-controlled-traumed-trial
#2
JOURNAL ARTICLE
Ludger Gerdesmeyer, Johannes Vester, Christian Schneider, Britt Wildemann, Christine Frank, Myron Schultz, Bernd Seilheimer, Alta Smit, Gino Kerkhoffs
BACKGROUND: Topical NSAIDs are widely used to treat ankle sprains. Traumed (Tr14) gel is a multicomponent formulation, demonstrating inflammation-resolution properties. METHODS: This multicenter, double-blind trial investigated the efficacy and safety of Tr14 gel versus placebo gel and non-inferiority versus 1% diclofenac gel, applied 3×/day for 7 days after acute lateral ankle sprain (EudraCT Number: 2016-004792-50). The primary outcome was AUC for pain on passive movement, assessed by VAS from baseline to Days 4 and 7...
February 1, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/37807567/h-33-lesi%C3%A3-n-cerebral-traum%C3%A3-tica-calidad-de-vida-en-un-grupo-de-pacientes-puertorrique%C3%A3-os
#3
JOURNAL ARTICLE
Zuleyka Lorenzo Sanchez, Yazdel Guzmán, Mairim Vega
OBJETIVOS: Adultos con lesión cerebral traumática (LCT) pueden sufrir de una disminución en calidad de vida (CAL) asociada al desarrollo de diagnósticos comórbidos. En Puerto Rico (PR), la información sobre esta población es limitada. Este estudio tuvo como objetivo describir las características sociodemográficas, diagnósticos comórbidos y CAL reportados por un cohorte de pacientes con LCT en PR. METODOLOGÍA: En este estudio de tipo no experimental transversal, con enfoque cuantitativo y alcance descriptivo, participaron 40 adultos puertorriqueños (23-63 años de edad) con historial de LCT y al menos un año de recuperación...
October 8, 2023: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://read.qxmd.com/read/37602979/lung-protection-after-severe-thermal-burns-with-adenosine-lidocaine-and-magnesium-alm-resuscitation-and-importance-of-shams-in-a-rat-model
#4
JOURNAL ARTICLE
Lisa M Davenport, Hayley L Letson, Geoffrey P Dobson
The management of severe burns remains a complex challenge. Adenosine, lidocaine and magnesium (ALM) resuscitation therapy has been shown to protect against hemorrhagic shock and traumatic injury. The aim of the present study was to investigate the early protective effects of small-volume ALM fluid resuscitation in a rat model of 30% total body surface area (TBSA) thermal injury. Male Sprague-Dawley rats (320-340g; n=25) were randomly assigned to: 1) Sham (surgical instrumentation and saline infusion, without burn, n=5), 2) Saline resuscitation group (n=10), or 3) ALM resuscitation group (n=10)...
August 21, 2023: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://read.qxmd.com/read/37226072/-pneumobilia-pneumoperitoneum-and-pneumowirsung-of-traumatic-etiology-case-report-and-review-of-the-literature
#5
JOURNAL ARTICLE
Siomara Aransuzú Ch Ávez-S Ánchez, Álvaro Bellido-Caparó, Ramón Alvarado-Jaramillo, César Augusto Ramírez-Cotrina, Martín Tagle-Arróspide
Pneumobilia is a phenomenon associated with the presence of a biliary-enteric fistula or manipulation of the bile duct during procedures or surgical interventions that cause dysfunction of the sphincter of Oddi. A known, but infrequently reported event, is the increase in intraabdominal pressure after closed abdominal trauma, which causes pneumobilia due to a mechanism of retrograde air leakage towards the bile duct. Depending on the general compromise of each patient, the prognosis can vary from a benign condition that only requires conservative management, to being life threatening...
2023: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://read.qxmd.com/read/37207047/end-to-end-dialogue-structure-parsing-on-multi-floor-dialogue-based-on-multi-task-learning
#6
JOURNAL ARTICLE
Seiya Kawano, Koichiro Yoshino, David Traum, Satoshi Nakamura
A multi-floor dialogue consists of multiple sets of dialogue participants, each conversing within their own floor. In the multi-floor dialogue, at least one multi-communicating member who is a participant of multiple floors and coordinates each to achieve a shared dialogue goal. The structure of such dialogues can be complex, involving intentional structure and relations that are within or across floors. In this study, We proposed a neural dialogue structure parser with an attention mechanism that applies multi-task learning to automatically identify the dialogue structure of multi-floor dialogues in a collaborative robot navigation domain...
2023: Frontiers in Robotics and AI
https://read.qxmd.com/read/37042410/-end-of-life-dreams-and-visions
#7
JOURNAL ARTICLE
Annina Seiler, Stefan Pelz, Fanny Wolfensberger, Caroline Hertler, Markus Schettle, Mathias Schlögl, Simon Peng-Keller, David Blum
End-of-Life Dreams and Visions Abstract: End-of life dreams and visions (ELDVs) or so-called death bed phenomena are transcendent experiences at the end of life that can be visual, auditory and/or kinesthetic, and often include visions of (deceased) loved ones, close friends or perceptions of places, travels, bright lights, or music. ELDVs typically occur weeks to hours prior to death and may comfort the dying and prepare spiritually for the end of life. Such experiences are frequently reported by dying individuals, the prevalence varying between 30 and 80%, but in the clinical context ELDVs are usually neglected, but interpreted and treated as pathological changes in the brain that result in, and from, delirium...
April 2023: Praxis
https://read.qxmd.com/read/36941764/the-anima-as-an-archetype-of-human-resilience-in-the-face-of-calamity
#8
JOURNAL ARTICLE
Mei-Fun Kuang
This paper will provide a theoretical basis for looking at a dream in the analysis of a client during a calamity. Finding the archetype of the anima is a way of responding to a crisis, in this case to the COVID-19 pandemic period. With all the basic instincts disrupted by a catastrophe, the emergence of the anima, as archetype of life, is there to remind us how to survive and recover. The anima archetype, often representing psychological resilience in ancient myths, shows up in dreams to guide human transformation from the struggle to survive trauma to the art of living a full life...
March 20, 2023: Journal of Analytical Psychology
https://read.qxmd.com/read/36604853/equity-factors-in-pediatric-transplant-listing-initial-findings-from-a-single-center-review
#9
JOURNAL ARTICLE
Dawn Freiberger, Brendan Kimball, Avram Z Traum, Laura Berbert, Laura O'Melia, Kevin P Daly, Heung B Kim, Kristine D McKenna
BACKGROUND: In order to improve transparency within the patient selection process, a transplant listing advisory committee was formed within the Boston Children's Hospital Pediatric Transplant Center. Its mission is to promote equity in access to organ transplantation by ensuring that the institutional transplant selection criteria are fair, unbiased, and nondiscriminatory. The committee conducts comprehensive case and data review of individual characteristics and reviews in aggregate to identify potential systems bias...
January 5, 2023: Pediatric Transplantation
https://read.qxmd.com/read/36511429/african-american-womens-experience-of-birth-traum
#10
JOURNAL ARTICLE
Courtney Evans
OBJECTIVE: This study will seek to understand the lived experiences of birth trauma among African American women. BACKGROUND: Racial discrimination affects society and individuals, both physically and mentally. Racial discrimination has the capacity to affect birth outcomes (Alhusen et al., 2016). Overall, adverse pregnancy outcomes in general have been found to be higher in African Americans than in Caucasians (Christian et al., 2012). Reducing disparities in birth outcomes has been said to be a national priority in the U...
December 13, 2022: Journal of Reproductive and Infant Psychology
https://read.qxmd.com/read/36440730/the-spiral-of-plastic-pollution-a-compensatory-urge-from-the-collective-unconscious-for-an-ecological-psychological-transformation-of-civilization
#11
JOURNAL ARTICLE
Susanna Bucher
This article explores the symbolism of plastic pollution. Plastic and microplastic particles are now found everywhere - in the Arctic, in deep ocean trenches, in human organs - and plastic accumulates in our oceans forming gigantic spiral-shaped garbage patches. Both spiral symbolism and E.A. Poe's 'Maelström' are suggestive of a necessary fundamental ecological-psychological transformation of our one-sidedly logos-dominated civilization. Plastic, the author argues, has become a carrier of our longing for immortality: in plastic, humanity has synthesized an 'immortal', a virtually non-biodegradable substance...
November 2022: Journal of Analytical Psychology
https://read.qxmd.com/read/36440720/dark-feet-and-dark-wings-penetrating-the-depths-of-the-earth
#12
JOURNAL ARTICLE
Robin B Zeiger
The author, although an analyst, is an initiate into the topic of environmental destruction. Following Wendell Berry, she enters the dark and begins a journey of dream-like reflection, weaving images from her own dream and drawing on the work of Vaughan, Bernstein, Soloveitchik and Sacks. She asks, 'not if but where does climate change enter the room?'. The second half of the paper focuses on the manifestations of environmental destruction in dreams and sandplay from three patients and one dream group participant...
November 2022: Journal of Analytical Psychology
https://read.qxmd.com/read/36349838/georges-perec-s-zeit-raum-creating-a-space-of-remembrance
#13
JOURNAL ARTICLE
Anat Tzur Mahalel
Georges Perec's memoir of his analysis, "The Scene of a Stratagem" (1977), is part of a literary oeuvre characterized by innovative forms addressing the paradoxical task of telling a story that cannot be told. His life history was constructed from memory traces, veiled behind the untimely death of his parents in World War II. The memoir tells the story of his analysis in adulthood with Jean-Bertrand Pontalis, at a time when Perec was struggling with depression and writer's block. Beneath doubts and the tedious analytic routine, Perec presents analysis as a space in which memory traces can be given new life...
October 2022: Journal of the American Psychoanalytic Association
https://read.qxmd.com/read/36314517/georges-perec-s-zeit-raum-creating-a-space-of-remembrance
#14
JOURNAL ARTICLE
Anat Tzur Mahalel
Georges Perec's memoir of his analysis, "The Scene of a Stratagem" (1977), is part of a literary oeuvre characterized by innovative forms addressing the paradoxical task of telling a story that cannot be told. His life history was constructed from memory traces, veiled behind the untimely death of his parents in World War II. The memoir tells the story of his analysis in adulthood with Jean-Bertrand Pontalis, at a time when Perec was struggling with depression and writer's block. Beneath doubts and the tedious analytic routine, Perec presents analysis as a space in which memory traces can be given new life...
October 2022: Journal of the American Psychoanalytic Association
https://read.qxmd.com/read/36221844/-identification-of-injury-disease-relationship-in-rracture-after-osteogenesis-imperfecta-traum%C3%AF-a-case-report
#15
JOURNAL ARTICLE
超 王, 春 华 夏
No abstract text is available yet for this article.
June 25, 2022: Fa Yi Xue za Zhi
https://read.qxmd.com/read/36210940/clinical-presentation-and-management-of-nephrotic-syndrome-in-the-first-year-of-life-a-report-from-the-pediatric-nephrology-research-consortium
#16
JOURNAL ARTICLE
Alexandru R Constantinescu, Tej K Mattoo, William E Smoyer, Larry A Greenbaum, Jianli Niu, Noel Howard, Melissa Muff-Luett, Elizabeth B Benoit, Avram Traum, Ali A Annaim, Scott E Wenderfer, Emilee Plautz, Michelle N Rheault, Robert L Myette, Katherine E Twombley, Yu Kamigaki, Belkis Wandique-Rapalo, Mohammad Kallash, Tetyana L Vasylyeva
BACKGROUND AND OBJECTIVES: Nephrotic syndrome (NS) in the first year of life is called congenital (CNS) if diagnosed between 0-3 months, or infantile (INS) if diagnosed between 3-12 months of age. The aim of this study was to determine if there were clinically meaningful differences between CNS and INS patients, regarding clinical presentation, management and outcomes. DESIGN SETTING PARTICIPANTS AND MEASUREMENTS: Eleven Pediatric Nephrology Research Consortium sites participated in the study, using IRB-approved retrospective chart reviews of CNS and INS patients born between 1998 and 2019...
2022: Frontiers in Pediatrics
https://read.qxmd.com/read/35856540/inner-outer-couple-anima-and-animus-revisited-new-perspectives-for-a-clinical-approach-in-transition
#17
JOURNAL ARTICLE
Mario E Saiz, Claudia Grez
The conflicts of the outer couple (crises, separations, divorces) with a high incidence in the rates of depression, reveal the archetypal dysfunction of the relationship between the inner-couple (in-shadow) and the outer-couple (in-crisis). To understand this in depth, a new animated and integrated model of the masculine (animus) and the feminine (anima) is explored. It is a transformational model, in which Jung's contributions are integrated and understood as knowledge in transition. Masculine and feminine cosmogonic principles are personified in the human psyche as anima-animus archetypes-complexes...
April 2022: Journal of Analytical Psychology
https://read.qxmd.com/read/35655038/survival-of-neonates-born-with-kidney-failure-during-the-initial-hospitalization
#18
JOURNAL ARTICLE
Donna J Claes, Troy Richardson, Matthew W Harer, Mahima Keswani, Alicia Neu, Allison C Redpath Mahon, Michael J Somers, Avram Z Traum, Bradley A Warady
BACKGROUND: Survival to hospital discharge in neonates born with kidney failure has not been previously described. METHODS: This was a retrospective, observational analysis of the Pediatric Health Information System (PHIS) database from 2005 to 2019. Primary outcome was survival at discharge; secondary outcomes were hospital and ICU length of stay (LOS). Univariate analysis was performed to describe the population by birth weight (BW) and characterize survival; multivariable generalized liner mixed modeling assuming a binomial distribution and logit link was performed to identify mortality risk factors...
June 2, 2022: Pediatric Nephrology
https://read.qxmd.com/read/35652909/prediction-of-trauma-mortality-incorporating-pre-injury-comorbidities-into-existing-mortality-scoring-indices
#19
JOURNAL ARTICLE
Nasim Ahmed, Yen-Hong Kuo
OBJECTIVES: The purpose of the study is to develop a comprehensive risk score of mortality in trauma victims that can predict the in-hospital mortality better than trauma injury severity score (TRISS) and A Severity Characterization of Trauma (ASCOT) score. METHODS: All hospitalized trauma patients, between the ages of 16 and 89 years old were included in the study. The National Trauma Quality Improvement Program (TQIP) database of the calendar year 2011-2016 was accessed for the development of a traum mortality scoring system (TMS)...
September 2022: American Surgeon
https://read.qxmd.com/read/35642629/%C3%AE-cell-dysfunction-in-islets-from-nondiabetic-glutamic-acid-decarboxylase-autoantibody-positive-individuals
#20
JOURNAL ARTICLE
Nicolai M Doliba, Andrea V Rozo, Jeffrey Roman, Wei Qin, Daniel Traum, Long Gao, Jinping Liu, Elisabetta Manduchi, Chengyang Liu, Maria L Golson, Golnaz Vahedi, Ali Naji, Franz M Matschinsky, Mark A Atkinson, Alvin C Powers, Marcela Brissova, Klaus H Kaestner, Doris A Stoffers
BACKGROUNDMultiple islet autoantibodies (AAbs) predict the development of type 1 diabetes (T1D) and hyperglycemia within 10 years. By contrast, T1D develops in only approximately 15% of individuals who are positive for single AAbs (generally against glutamic acid decarboxylase [GADA]); hence, the single GADA+ state may represent an early stage of T1D.METHODSHere, we functionally, histologically, and molecularly phenotyped human islets from nondiabetic GADA+ and T1D donors.RESULTSSimilar to the few remaining β cells in the T1D islets, GADA+ donor islets demonstrated a preserved insulin secretory response...
June 1, 2022: Journal of Clinical Investigation
keyword
keyword
28906
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.