Alexandru R Constantinescu, Tej K Mattoo, William E Smoyer, Larry A Greenbaum, Jianli Niu, Noel Howard, Melissa Muff-Luett, Elizabeth B Benoit, Avram Traum, Ali A Annaim, Scott E Wenderfer, Emilee Plautz, Michelle N Rheault, Robert L Myette, Katherine E Twombley, Yu Kamigaki, Belkis Wandique-Rapalo, Mohammad Kallash, Tetyana L Vasylyeva
BACKGROUND AND OBJECTIVES: Nephrotic syndrome (NS) in the first year of life is called congenital (CNS) if diagnosed between 0-3 months, or infantile (INS) if diagnosed between 3-12 months of age. The aim of this study was to determine if there were clinically meaningful differences between CNS and INS patients, regarding clinical presentation, management and outcomes. DESIGN SETTING PARTICIPANTS AND MEASUREMENTS: Eleven Pediatric Nephrology Research Consortium sites participated in the study, using IRB-approved retrospective chart reviews of CNS and INS patients born between 1998 and 2019...
2022: Frontiers in Pediatrics