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https://www.readbyqxmd.com/read/28449510/chondromatous-hamartoma-of-cervical-esophagus-a-case-report-and-literature-review
#1
Chong Zhang, Jinming Xu, Zhitian Wang, Zhehao He, Hanjin Yang, Jian Hu
Esophageal chondromatous hamartomas are very rare tumors, characterized by proliferating hyaline cartilage cells. We described the case of a 64-year-old woman, with a progressive foreign body sensation in the laryngopharynx caused by an intraluminal pedicled mass. Transcervical esophagectomy was performed and intraoperative biopsy revealed the mass was a cervical esophageal chondromatous hamartoma. The patient's postoperative course was uneventful and she recovered well. A review of the literature was conducted, and the symptoms, locations, histopathology findings, treatment methods and follow up results of esophageal hamartoma cases were summarized...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28449429/pancreatic-lymphoepithelial-cysts-diagnosed-with-endosonography-guided-fine-needle-aspiration
#2
Youngmin Oh, Yonghyeok Choi, Seung Myoung Son, Jisun Lee, Yook Kim, Joung Ho Han, Seon Mee Park
Although lymphoepithelial cysts (LECs) of the pancreas are benign lesions, most of them have been treated with surgical resection due to diagnostic difficulty. We report a 66-year-old woman diagnosed with pancreatic LECs. Abdominal ultrasound revealed two masses in the pancreas, which were not visible on the abdominal computed tomography. In an abdominal magnetic resonance imaging, pancreas lesions showed solid tumors, which revealed a low signal intensity on T1-, moderate high signal intensity on T2 weighted images, and homogeneous delayed enhancement in the portal venous phase...
April 25, 2017: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/28448992/bethesda-made-it-clearer-a-review-of-542-patients-in-a-single-institution
#3
Yunus Acar, Lütfi Doğan, H Erhan Güven, Bülent Aksel, Niyazi Karaman, Cihangir Özaslan, M Ali Gülçelik
BACKGROUND: It is essential to interpret fine needle aspiration biopsy (FNAB) material correctly to create a common language among pathologists and surgeons, leading to a uniform approach to thyroid nodule management. We aimed to compare FNAB reports of patients at our institution who were treated with total thyroidectomy, before and after the Bethesda classification system. PATIENTS AND METHODS: Patients who underwent total thyroidectomy for thyroid nodules are reviewed...
March 21, 2017: Oncology Research and Treatment
https://www.readbyqxmd.com/read/28448960/utility-of-genomic-analysis-in-differentiating-synchronous-and-metachronous-lung-adenocarcinomas-from-primary-adenocarcinomas-with-intrapulmonary-metastasis
#4
Jad Saab, Hamid Zia, Susan Mathew, Michael Kluk, Navneet Narula, Helen Fernandes
Distinguishing synchronous and metachronous primary lung adenocarcinomas from adenocarcinomas with intrapulmonary metastasis is essential for optimal patient management. In this study, multiple lung adenocarcinomas occurring in the same patient were evaluated using comprehensive histopathologic evaluation supplemented with molecular analysis. The cohort included 18 patients with a total of 52 lung adenocarcinomas. Eleven patients had a new diagnosis of multiple adenocarcinomas in the same lobe (n=5) or different lobe (n=6)...
April 24, 2017: Translational Oncology
https://www.readbyqxmd.com/read/28448416/analysis-of-a-steerable-needle-for-fine-needle-aspiration-and-biopsy-efficiency-and-radiation-dose-compared-with-a-conventional-straight-needle
#5
Sandra Rutigliano, John A Abraham, Barry E Kenneally, Adam C Zoga, Mika Nevalainen, Johannes B Roedl
PURPOSE: Percutaneous computed tomography (CT)-guided needle biopsy has proven to be an efficacious method for sampling of many soft tissue lesions, especially deep-seated masses in the abdomen and pelvis. This study sought to test the potential for a novel steerable needle to improve localization and to reduce procedure duration and radiation dose compared with a conventional straight needle. MATERIAL AND METHODS: A fresh, raw meat sample (lean bovine flank) was imbedded with cylindrical radiopaque and radiolucent obstacles designed to simulate vessels (radiolucent objects) and bones (radiopaque objects) on CT...
April 26, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28447904/fine-needle-aspiration-versus-frozen-section-in-the-evaluation-of-malignant-thyroid-nodules-in-patients-with-the-diagnosis-of-suspicious-for-malignancy-or-malignancy-by-fine-needle-aspiration
#6
Qin Ye, Jennifer S Woo, Qunzi Zhao, Ping Wang, Pintong Huang, Lirong Chen, Xin Li, Kanlun Xu, Ying Yong, Stephanie Sung-Eun Yang, Jianyu Rao
CONTEXT: - The Bethesda System for Reporting Thyroid Cytopathology recommends against the use of intraoperative frozen section (FS) during lobectomy of a thyroid nodule with a fine-needle aspiration (FNA) diagnosis of malignant. Bethesda recommendations for FS in the FNA category of suspicious for malignancy (SFM) is less well-defined. In some institutions in China, FS examination is performed during lobectomy even for FNA-proven malignant cases. OBJECTIVE: - -To compare the efficacy of FNA versus FS in the evaluation of malignant thyroid lesions...
May 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/28447590/concomitant-thyroid-cancer-in-patients-with-primary-hyperparathyroidism-in-an-endemic-goitre-region
#7
Besir Simsek, Cem Emir Guldogan, Sabri Ozden, Baris Saylam, Serif Melih Karabeyoglu, Mesut Tez
OBJECTIVE: Primary hyperparathyroidism (pHPT) is often accompanied by underlying thyroid pathology and 1 to 36% of these thyroid pathologies are malignant. How the identification of these lesions affects patient management is unclear. We present a single-center experience with the prevalence of concomitant thyroid cancer in patients who underwent parathyroidectomy for pHPT. MATERIALS AND METHODS: This was a retrospective cohort study. Two hundred-two patients with primary hyperparathyroidism included study...
2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28447425/ten-color-15-antibody-flow-cytometry-panel-for-immunophenotyping-of-lymphocyte-population
#8
REVIEW
A Rajab, O Axler, J Leung, M Wozniak, A Porwit
We have developed a lymphoproliferative disorder screening tube (LPD-ST) with the aim to provide comprehensive immunophenotyping of lymphocyte subsets with minimal need for additional testing. The LPD-ST consists of CD4/kappa FITC, CD8/lambda PE, CD3/CD14ECD, CD38PC5.5, CD20/CD56PC7, CD10APC, CD19APC-A700, CD5APC-A750, CD57/CD23PB and CD45KO. The LPD-ST was validated against previously used lymphocyte subset panels in Canada (n=60) and in Sweden (n=43) and against the OneFlow(™) LST (n=60). The LPD-ST panel was then implemented in clinical practice using dried monoclonal antibody reagents (Duraclone(®) ) on 649 patient samples in Sweden...
May 2017: International Journal of Laboratory Hematology
https://www.readbyqxmd.com/read/28447327/uptake-of-123-i-metaiodobenzylguanidine-by-gastrointestinal-stromal-tumor
#9
Patommatat Bhanthumkomol, Susumu Hijioka, Nobumasa Mizuno, Takamichi Kuwahara, Nozomi Okuno, Ayako Ito, Tsutomu Tanaka, Makoto Ishihara, Yutaka Hirayama, Sachiyo Onishi, Yasumasa Niwa, Masahiro Tajika, Yuichi Ito, Eiichi Sasaki, Yoshitaka Inaba, Yasuhiro Shimizu, Yasushi Yatabe, Kazuo Hara
A 52-year-old woman was admitted with a large intraabdominal mass. (123)I- metaiodobenzylguanidine ((123)I-MIBG) scintigraphy revealed considerable (123)I-MIBG accumulation by the mass that was compatible with a diagnosis of paraganglioma. However, a spindle cell tumor that was identified using endoscopic ultrasound-guided fine needle aspiration before surgery was positive for CD117. The surgically resected mass was confirmed as a gastrointestinal stromal tumor (GIST). Although the mechanism of (123)I-MIBG uptake by GIST has not been elucidated, GIST should be included in the differential diagnosis of intra-abdominal tumor with (123)I-MIBG uptake...
April 26, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/28446970/the-role-of-endobronchial-ultrasound-versus-mediastinoscopy-for-non-small-cell-lung-cancer
#10
REVIEW
Katarzyna Czarnecka-Kujawa, Kazuhiro Yasufuku
This review provides an update on the current role of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) and mediastinoscopy (Med) in assessment of patients with non-small cell lung cancer (NSCLC). Invasive mediastinal lymph node (LN) staging is the major application for both of these techniques. Up until recently, Med was the gold standard for invasive mediastinal LN staging in NSCLC. However, EBUS-TBNA has shown to be equivalent, and in some studies better than Med for invasive staging of lung cancer...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28445954/a-clinically-feasible-multiplex-proteomic-immunoassay-as-a-novel-functional-diagnostic-for-pancreatic-ductal-adenocarcinoma
#11
Kian-Huat Lim, Emma Langley, Feng Gao, Jingqin Luo, Lin Li, Gary Meyer, Phillip Kim, Sharat Singh, Vladamir M Kushnir, Dayna S Early, Daniel K Mullady, Steven A Edmundowicz, Sachin Wani, Faris M Murad, Dengfeng Cao, Riad R Azar, Andrea Wang-Gillam
To date, targeted therapy for pancreatic ductal adenocarcinoma (PDAC) remains largely unsuccessful in the clinic. Current genomics-based technologies are unable to reflect the quantitative, dynamic signaling changes in the tumor, and require larger tumor samples that are difficult to obtain in PDAC patients. Therefore, a highly sensitive functional tool that can reliably and comprehensively inform intra-tumoral signaling events is direly needed to guide treatment decision. We tested the utility of a highly sensitive proteomics-based functional diagnostic platform, Collaborative Enzyme Enhanced Reactive-immunoassay (CEERTM), on fine-needle aspiration (FNA) samples obtained from 102 patients with radiographically-evident pancreatic tumors...
April 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28445104/endoscopic-ultrasound-guided-direct-portal-pressure-measurement-using-a-digital-pressure-wire-with-real-time-remote-display-a-survival-study
#12
Allison R Schulman, Christopher C Thompson, Marvin Ryou
BACKGROUND: Portal hypertension is necessary for the development of most clinical complications of cirrhosis. We recently reported a novel, endoscopic ultrasound (EUS)-guided technique for direct portal pressure measurements using a digital pressure wire. AIMS: The aims of this study were to (1) evaluate safety in an animal survival model and (2) compare direct portal vein (PV) versus transhepatic access of a first-order venule. MATERIALS AND METHODS: Yorkshire pigs, weighing 40-55 kg...
April 26, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28444527/endoscopic-ultrasound-guided-fine-needle-aspiration-of-extra-rectal-lesions
#13
J Lim, S A Norton, N A Wong, M G Thomas
No abstract text is available yet for this article.
April 25, 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/28442140/cystic-neutrophilic-granulomatous-mastitis-associated-with-corynebacterium-including-corynebacterium-kroppenstedtii
#14
Kate J Johnstone, Jennifer Robson, Sarah G Cherian, Jenny Wan Sai Cheong, Kris Kerr, Judith F Bligh
Granulomatous (lobular) mastitis is a rare inflammatory breast disease affecting parous reproductive-aged women. Once considered idiopathic, there is growing evidence of an association with corynebacteria infection, especially in the setting of a distinct histological pattern termed cystic neutrophilic granulomatous mastitis (CNGM). We describe 15 cases with histological features either confirming (n = 12) or suggesting (n = 3) CNGM, and concurrent microbiological evidence of Corynebacterium species. The organism was detected by culture or 16S rRNA gene sequencing of specimens obtained at surgery or fine needle aspiration...
April 22, 2017: Pathology
https://www.readbyqxmd.com/read/28441814/-current-situation-and-thinking-of-diagnosis-and-treatment-in-some-types-of-thyroid-cancer
#15
X Y Yang, Y Yu, D P Li, L Dong
As arising incidence of thyroid cancer, the treatment for thyroid carcinoma is becoming increasingly standardized. But there are different opinions on the treatment for some types of thyroid cancers, including the determination of operative opportunity, surgical method, and follow-up observation plan. There are mainly two categories of patients, namely the patients diagnosed as familial thyroid cancer mutation carriers through family screening, including medullary thyroid carcinoma and familial nonmedullary thyroid carcinoma, and the patients with thyroid microcarcinoma that can be observed after diagnosed by fine needle biopsy cytology...
April 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28441801/-prediction-of-occult-carcinoma-in-contralateral-nodules-based-on-the-ultrasonic-features-of-unilateral-papillary-thyroid-carcinoma
#16
L M Yang, Q Li, B W Zhao, J G Lyu, H S Xu, L L Xu, S Y Li, L Gao, J Zhu
Objective: To investigate the occurrence of occult carcinoma in contralateral lobes based on the ultrasonic features of unilateral papillary thyroid carcinoma. Methods: The study included 202 consecutives cases of unilateral papillary thyroid carcinoma with benign nodules in the contralateral lobe identified by preoperative ultrasound or fine-needle aspiration from June 2014 to December 2015. All patients received total thyroidectomies, and with postoperative pathological examination they were divided into two groups, one including 60 cases with positive occult cancer and another one consisting of 142 cases with negative occult cancer...
April 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28440914/transesophageal-bronchoscopic-ultrasound-guided-fine-needle-aspiration-eus-b-fna-pushing-the-boundaries-in-the-diagnosis
#17
Ravindra Mehta, Pavan Biraris, Swarna Shivakumar, Seema Misra, Parameswaran Anoop, Srikanta J T
Isolated mediastinal adenopathy is a diagnostic challenge in the paediatric population, often requiring invasive surgical procedures for diagnosis. We describe a novel minimally invasive modality in a 20 month toddler-transesophageal bronchoscopic ultrasound-guided fine-needle aspiration (EUS-B-FNA). This is the youngest reported use of this modality, highlighting feasibility, technical issues, safety, and rapid diagnosis leading to expedited treatment.
April 25, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28440348/diagnostic-utility-of-endoscopic-ultrasonography-elastography-in-the-evaluation-of-solid-pancreatic-masses-a-meta-analysis-and-systematic-review
#18
Yi Lu, Lu Chen, Chujun Li, Honglei Chen, Jinhua Chen
AIM: The accuracy for endoscopic ultrasonography-elastography (EUS-EG) in the evaluation of solid pancreatic masses varies greatly and the pooled results have not been updated since 2013. Also, there still lack a comprehensive comparison among EUS-EG, contrast-enhanced EUS (CE-EUS), and EUS-guided fine needle aspiration (EUS-FNA).Material and methods: A thorough search was made for diagnostic trials investigating the role of EUS-EG in solid pancreatic masses. Meta-Disc was used to calculate the pooled sensitivity, specificity, diagnostic odds ratio and summary receiver operator characteristics...
April 22, 2017: Medical Ultrasonography
https://www.readbyqxmd.com/read/28440242/esophageal-adenocarcinoma-metastasis-in-the-left-adrenal-gland-diagnosed-by-endoscopic-ultrasound-guided-fine-needle-aspiration
#19
Everton Hadlich, Augusto P C Carbonari, Maurício S Assef, Osvaldo M Araki, Frank S Nakao, Mauro T A Saieg, Lúcio G B Rossini
No abstract text is available yet for this article.
March 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28440240/cystic-pancreatic-lymphangioma-diagnosed-with-endoscopic-ultrasound-guided-fine-needle-aspiration
#20
Ikram Hussain, Tiing Leong Ang
Pancreatic lymphangiomas are rare, but benign neoplasms. Historically, the diagnoses in various case reports were mostly made after surgical resection. There are emerging data concerning the utility of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) to differentiate it from more sinister pancreatic cystic neoplasms. A confident preoperative diagnosis with EUS-FNA is crucial to avoid unnecessary workup or surgery, especially for small and asymptomatic lesions. Here, we present a rare case of asymptomatic pancreatic lymphangioma which was diagnosed with EUS-FNA...
March 2017: Endoscopic Ultrasound
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