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https://www.readbyqxmd.com/read/28861404/effectiveness-of-percutaneous-tibial-nerve-stimulation-in-the-treatment-of-overactive-bladder-syndrome
#1
REVIEW
Liesbeth L de Wall, John Pfa Heesakkers
Overactive bladder syndrome (OAB) is a common condition affecting adults and children worldwide, resulting in a substantial economic and psychological burden. Percutaneous tibial nerve stimulation (PTNS) is derived from acupuncture used in Chinese traditional medicine and was first described in the early 1980s. It is a neuromodulation technique used to modulate bladder function and facilitate storage. Being a minimally invasive, easily applicable, but time-consuming treatment, future developments with implantable devices might be the solution for the logistical problems and economic burden associated with PTNS on the long term...
2017: Research and Reports in Urology
https://www.readbyqxmd.com/read/28850813/clinical-application-of-the-newborn-behavioral-observation-nbo-system-to-characterize-the-behavioral-pattern-of-newborns-at-biological-and-social-risk
#2
Marina Aguiar Pires Guimarães, Claudia Regina Lindgren Alves, Ana Amélia Cardoso, Márcia Gomes Penido, Lívia de Castro Magalhães
OBJECTIVE: To compare the behavior of preterm newborns (PTNs) and full-term newborns (FTNs) using the Newborn Behavioral Observation (NBO) and to evaluate the mothers' experience when participating in this observation. METHOD: This was a cross-sectional study performed at a referral hospital for high-risk births, involving mothers and neonates before hospital discharge. The mothers answered the sociodemographic questionnaire, participated in the NBO session, and evaluated the experience by answering the parents' questionnaire at the end...
August 30, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28703936/randomized-clinical-trial-of-percutaneous-tibial-nerve-stimulation-versus-sham-electrical-stimulation-in-patients-with-faecal-incontinence
#3
RANDOMIZED CONTROLLED TRIAL
A A van der Wilt, G Giuliani, C Kubis, B P W van Wunnik, I Ferreira, S O Breukink, P A Lehur, F La Torre, C G M I Baeten
BACKGROUND: The aim was to assess the effects of percutaneous tibial nerve stimulation (PTNS) in the treatment of faecal incontinence (FI) by means of an RCT. METHODS: Patients aged over 18 years with FI were included in a multicentre, single-blinded RCT. The primary endpoint was reduction in the median or mean number of FI episodes per week. Secondary endpoints were changes in measures of FI severity, and disease-specific and generic quality of life. Outcomes were compared between PTNS and sham stimulation after 9 weeks of treatment...
August 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28687483/percutaneous-tibial-nerve-stimulation-therapy-for-overactive-bladder-syndrome-clinical-effectiveness-urodynamic-and-durability-evaluation
#4
Sergío Del Río-Gonzalez, Isabel M Aragon, Elisabeth Castillo, Francisco Milla-España, Alejandro Galacho, Javier Machuca, María F Lara, Bernardo Herrera-Imbroda
OBJECTIVE: To evaluate percutaneous tibial nerve stimulation (PTNS) effectiveness, durability, and impact on the pathophysiology of overactive bladder syndrome (OAB) in patients who have been previously treated with antimuscarinics without success. MATERIALS AND METHODS: A prospective study that included 200 women diagnosed with OAB between 2007 and 2015 at Virgen de la Victoria University Hospital (Málaga, Spain) was conducted. OAB patients were treated with PTNS therapy after antimuscarinic treatment failed...
July 4, 2017: Urology
https://www.readbyqxmd.com/read/28656519/where-are-we-headed-with-neuromodulation-for-overactive-bladder
#5
REVIEW
Kaitlin Jaqua, Charles R Powell
Overactive bladder (OAB) affects millions of people around the world and decreases quality of life for those affected. Over the past two decades, significant advances in treatment have transformed the lives of those with OAB. Sacral neuromodulation (SNM), posterior tibial nerve stimulation (PTNS), and dorsal genital nerve stimulation are the most effective contemporary treatment modalities. New techniques and bio-sensing schemes offer promise to advance therapy beyond what is currently available. Current neuromodulation techniques do not use real-time data from the body or input from the patient...
August 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28647458/predictors-of-efficacy-of-percutaneous-tibial-nerve-stimulation%C3%A2-for-fecal-incontinence-a-post-hoc-analysis-of%C3%A2-a%C3%A2-randomized-trial
#6
Emma J Horrocks, Sami A Chadi, Natasha J Stevens, Steven D Wexner, Charles H Knowles
BACKGROUND & AIMS: A recent UK multicenter, phase III trial (the CONtrol of Fecal Incontinence using Distal NeuromodulaTion Trial), demonstrated no significant clinical benefit of percutaneous tibial nerve stimulation (PTNS) over sham stimulation; however, this study did not analyze predictors of response. This study aimed to determine predictors of PTNS efficacy in adults with fecal incontinence (FI) using data from this randomized controlled trial. METHODS: The study population comprised 205 patients from the CONtrol of Fecal Incontinence using Distal NeuromodulaTion Trial, with original primary outcome (≥50% reduction in weekly FI episodes after 12 weeks of treatment) remaining the binary denominator of success or failure...
June 21, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28646940/management-of-refractory-idiopathic-overactive-bladder-intradetrusor-injection-of-botulinum-toxin-type-a-versus-posterior-tibial-nerve-stimulation
#7
Hammouda Sherif, Mostafa Khalil, Rabea Omar
INTRODUCTION: To compare the safety and efficacy of posterior tibial nerve stimulation (PTNS) versus an intradetrusor injection of botulinum toxin type-A (BTX-A) 100 U in the management of refractory idiopathic overactive bladder (OAB). MATERIALS AND METHODS: We randomized 60 patients with refractory idiopathic OAB to receive an intradetrusor injection of BTX-A 100 U or PTNS. We assessed the patients at baseline, 6 weeks, 3 months, 6 months, and 9 months, and determined their clinical symptoms, overall OAB symptom score, urgency score, quality-of-life score, and urodynamic study parameters...
June 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/28640440/frequency-dependent-inhibition-of-bladder-function-by-saphenous-nerve-stimulation-in-anesthetized-rats
#8
Zainab Moazzam, Paul B Yoo
AIMS: Percutaneous tibial nerve stimulation (PTNS) is an effective neuromodulation therapy for treating overactive bladder (OAB). The therapeutic effects are achieved by repeatedly applying electrical stimulation through a percutaneous needle electrode that is used to target the tibial nerve (TN). Anatomical studies indicate there can be multiple saphenous nerve (SAFN) branches located near the site of electrical stimulation, and therefore we investigated the possibility of evoking a bladder-inhibitory reflex by electrically activating the SAFN...
June 22, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28615976/clinical-utility-of-neurostimulation-devices-in-the-treatment-of-overactive-bladder-current-perspectives
#9
REVIEW
Dick Aw Janssen, Frank Mj Martens, Liesbeth L de Wall, Hendrikje Mk van Breda, John Pfa Heesakkers
OBJECTIVES: This review describes the evidence from established and experimental therapies that use electrical nerve stimulation to treat lower urinary tract dysfunction. METHODS: Clinical studies on established treatments such as percutaneous posterior tibial nerve stimulation (P-PTNS), transcutaneous electrical nerve stimulation (TENS), sacral nerve stimulation (SNS) and sacral anterior root stimulation (SARS) are evaluated. In addition, clinical evidence from experimental therapies such as dorsal genital nerve (DGN) stimulation, pudendal nerve stimulation, magnetic nerve stimulation and ankle implants for tibial nerve stimulation are evaluated...
2017: Medical Devices: Evidence and Research
https://www.readbyqxmd.com/read/28439675/a-pilot-study-assessing-the-efficacy-of-posterior-tibial-nerve-stimulation-in-the-treatment-of-low-anterior-resection-syndrome
#10
V Vigorita, S Rausei, P Troncoso Pereira, I Trostchansky, A Ruano Poblador, E Moncada Iribarren, C Facal Alvarez, A de San Ildefonso Pereira, E Casal Núñez
BACKGROUND: Low anterior resection for rectal cancer often results in severe bowel dysfunction, specifically low anterior resection syndrome (LARS), with symptoms such as incontinence, urgency, and frequent bowel movements. Percutaneous tibial nerve stimulation (PTNS) resulted in a high rate of success in patients with fecal incontinence. The aim of this study was to evaluate the effectiveness of treatment with PTNS in LARS and to identify predictors of the outcome of the technique. METHODS: The study was conducted from May 2012 to April 2015 at the Alvaro Cunqueiro Hospital, University Hospital Complex of Vigo, Spain...
April 24, 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/28391449/percutaneous-tibial-nerve-stimulation-ptns-success-rate-and-the-role-of-rectal-capacity
#11
Lukas Marti, Christian Galata, Ulrich Beutner, Franc Hetzer, Nicoletta Pipitone, Katja Wolff, Jan Borovicka, Walter Brunner, Michael Christian Sulz, Christine Maurus
PURPOSE: Percutaneous tibial nerve stimulation (pTNS) was originally developed to treat urinary incontinence. Recently, some case series have also documented its success in the treatment of fecal incontinence. Nevertheless, the mechanism underlying this effect remains unknown but may be related to changes in rectal capacity. The aim of this study was to investigate the success of pTNS for the treatment of fecal urge incontinence and assess the influence of rectal capacity on treatment efficacy...
April 8, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28371160/short-term-outcome-of-percutaneous-tibial-nerve-stimulation-for-low-anterior-resection-syndrome-results-of-a-pilot-study
#12
D F Altomare, A Picciariello, C Ferrara, R Digennaro, Y Ribas, M De Fazio
AIM: Percutaneous tibial nerve stimulation (PTNS) is a minimally invasive procedure, which has been demonstrated to be effective in faecal/urinary incontinence, but has never been tested in Low Anterior Resection Syndrome (LARS). The severity of LARS may be evaluated by the LARS-score, but rectal cancer treatments may also affect urinary and sexual function, which are not explored by the LARS-score. The TAPE-score is a new validated index addressing the overall pelvic-floor functions...
March 29, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28269268/posterior-tibial-nerve-stimulation-using-a-wirelessly-powered-system-in-anesthetized-cats
#13
Zainab Moazzam, Austin R Duke, Paul B Yoo
Posterior Tibial Nerve Stimulation (PTNS) is an effective overactive bladder (OAB) therapy where electrical pulses are typically delivered once per week in a 12-week stimulation regime. While the mechanism of action remains unknown, effective long-term delivery of PTNS has recently become a subject of concern. To this end, a multi-contact electrode was surgically placed in the hind limb region of anesthetized cats to (1) investigate the feasibility of using a wirelessly powered system to stimulate PTN afferents and (2) characterize implant-driven effects of stimulation frequency on modulating bladder activity...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268972/co-activation-of-saphenous-nerve-fibers-a-potential-therapeutic-mechanism-of-percutaneous-tibial-nerve-stimulation
#14
Christopher W Elder, Paul B Yoo
Percutaneous tibial nerve stimulation (PTNS) is a minimally invasive and effective treatment for overactive bladder (OAB). However, clinical trials show that positive therapeutic outcomes among patients are difficult to predict (failure rate = 35% to 50%). Inconsistencies in the stimulation amplitudes used clinically and those used in preclinical animal studies led us to hypothesize that OAB therapy involves a secondary bladder-inhibitory pathway. In this paper, we implemented and tested a computer model of the human lower leg that investigated the differential activation of the saphenous nerve (SAFN) and tibial nerve (TN) during percutaneous electrical stimulation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268971/electrical-stimulation-of-the-saphenous-nerve-in-anesthetized-rats-a-novel-therapeutic-approach-to-treating-overactive-bladder
#15
Zainab Moazzam, Paul B Yoo
Posterior Tibial Nerve Stimulation (PTNS) is a minimally invasive yet effective therapy for treating overactive bladder (OAB) symptoms with electrical stimulations applied at 20 Hz coupled with amplitudes approximating the foot-twitch threshold (T). However, pre-clinical studies indicate that PTNS-evoked bladder reflexes require stimulation amplitudes exceeding 2T. The objective of this work was to evaluate the presence of secondary low-threshold sensory pathways in the hind-limb region that can be a potential target of activation during clinical PTNS set-up...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227502/posterior-tibial-nerve-stimulation-using-a-wirelessly-powered-system-in-anesthetized-cats
#16
Zainab Moazzam, Austin R Duke, Paul B Yoo, Zainab Moazzam, Austin R Duke, Paul B Yoo, Paul B Yoo, Zainab Moazzam, Austin R Duke
Posterior Tibial Nerve Stimulation (PTNS) is an effective overactive bladder (OAB) therapy where electrical pulses are typically delivered once per week in a 12-week stimulation regime. While the mechanism of action remains unknown, effective long-term delivery of PTNS has recently become a subject of concern. To this end, a multi-contact electrode was surgically placed in the hind limb region of anesthetized cats to (1) investigate the feasibility of using a wirelessly powered system to stimulate PTN afferents and (2) characterize implant-driven effects of stimulation frequency on modulating bladder activity...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227181/co-activation-of-saphenous-nerve-fibers-a-potential-therapeutic-mechanism-of-percutaneous-tibial-nerve-stimulation
#17
Christopher W Elder, Paul B Yoo, Christopher W Elder, Paul B Yoo, Paul B Yoo, Christopher W Elder
Percutaneous tibial nerve stimulation (PTNS) is a minimally invasive and effective treatment for overactive bladder (OAB). However, clinical trials show that positive therapeutic outcomes among patients are difficult to predict (failure rate = 35% to 50%). Inconsistencies in the stimulation amplitudes used clinically and those used in preclinical animal studies led us to hypothesize that OAB therapy involves a secondary bladder-inhibitory pathway. In this paper, we implemented and tested a computer model of the human lower leg that investigated the differential activation of the saphenous nerve (SAFN) and tibial nerve (TN) during percutaneous electrical stimulation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227180/electrical-stimulation-of-the-saphenous-nerve-in-anesthetized-rats-a-novel-therapeutic-approach-to-treating-overactive-bladder
#18
Zainab Moazzam, Paul B Yoo, Zainab Moazzam, Paul B Yoo, Paul B Yoo, Zainab Moazzam
Posterior Tibial Nerve Stimulation (PTNS) is a minimally invasive yet effective therapy for treating overactive bladder (OAB) symptoms with electrical stimulations applied at 20 Hz coupled with amplitudes approximating the foot-twitch threshold (T). However, pre-clinical studies indicate that PTNS-evoked bladder reflexes require stimulation amplitudes exceeding 2T. The objective of this work was to evaluate the presence of secondary low-threshold sensory pathways in the hind-limb region that can be a potential target of activation during clinical PTNS set-up...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28124534/percutaneous-tibial-nerve-stimulation-versus-electrical-stimulation-with-pelvic-floor-muscle-training-for-overactive-bladder-syndrome-in-women-results-of-a-randomized-controlled-study
#19
RANDOMIZED CONTROLLED TRIAL
Carlo Vecchioli Scaldazza, Carolina Morosetti, Rosita Giampieretti, Rossana Lorenzetti, Marinella Baroni
INTRODUCTION: This study compared percutaneous tibial nerve stimulation (PTNS) versus electrical stimulation with pelvic floor muscle training (ES + PFMT) in women with overactive bladder syndrome (OAB). MATERIALS AND METHODS: 60 women with OAB were enrolled. Patients were randomized into two groups. In group A, women underwent ES with PFMT, in group B women underwent PTNS. RESULTS: A statistically significant reduction in the number of daily micturitions, episodes of nocturia and urge incontinence was found in the two groups but the difference was more substantial in women treated with PTNS; voided volume increased in both groups...
January 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/27802008/percutaneous-tibial-nerve-stimulation-versus-electrical-stimulation-with-pelvic-floor-muscle-training-for-overactive-bladder-syndrome-in-women-results-of-a-randomized-controlled-study
#20
Carlo Vecchioli Scaldazza, Carolina Morosetti, Rosita Giampieretti, Rossana Lorenzetti, Marinella Baroni
INTRODUCTION: This study compared percutaneous tibial nerve stimulation (PTNS) versus electrical stimulation with pelvic floor muscle training (ES + PFMT) in women with overactive bladder syndrome (OAB). MATERIALS AND METHODS: 60 women with OAB were enrolled. Patients were randomized into two groups. In group A, women underwent ES with PFMT, in group B women underwent PTNS. RESULTS: A statistically significant reduction in the number of daily micturitions, episodes of nocturia and urge incontinence was found in the two groups but the difference was more substantial in women treated with PTNS; voided volume increased in both groups...
January 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
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