Reinhard Singer, Arianeb Mehrabi, Peter Schemmer, Arash Kashfi, Ute Hegenbart, Hartmut Goldschmidt, Stefan Schönland, Arnt Kristen, Thomas Dengler, Martina Müller-Schilling, Peter Sauer, Ayhan Dogan, Ernst Hund, Burkhard Helmke, Philipp Schnabel, Klaus Altland, Reinhold Linke, Helmut Friess, Jan Schmidt, Markus W Büchler, Thomas W Kraus
Familial amyloidotic polyneuropathy (FAP) is an inherited disorder with the systemic deposition of amyloid fibrils containing mutant transthyretin variants. The mutant form of transthyretin amyloidosis is produced mainly in the liver. Successful liver transplantation (LTx) could eliminate the source of the variant transthyretin molecule, and is now the only known curative treatment. The aim of this study is to evaluate the results of LTx for FAP at the University of Heidelberg. Eleven patients who underwent LTx between 1985 and 2004 with the diagnosis of FAP were evaluated...
September 27, 2005: Transplantation