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https://www.readbyqxmd.com/read/29792875/modelling-the-skip-and-resurgence-of-japanese-encephalitis-epidemics-in-hong-kong
#1
Shi Zhao, Yijun Lou, Alice P Y Chiu, Daihai He
Japanese encephalitis virus (JEV) is a zoonotic mosquito-borne virus, persisting in pigs, Ardeid birds and Culex mosquitoes. It is endemic to China and Southeastern Asia. The case-fatality ratio (CFR) or the rate of permanent psychiatric sequelae is 30% among symptomatic patients. There were no reported local JEV human cases between 2006 to 2010 in Hong Kong, but it was followed by a resurgence of cases from 2011 to 2017. The mechanism behind this "skip-and-resurgence" patterns is unclear. This work aims to reveal the mechanism behind the "skip-and-resurgence" patterns using mathematical modelling and likelihood-based inference techniques...
May 21, 2018: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/29792481/risk-and-protective-factors-of-intimate-partner-violence-among-south-asian-immigrant-women-and-perceived-need-for-services
#2
Bushra Sabri, Michelle Simonet, Jacquelyn C Campbell
OBJECTIVES: Limited research exists on multilevel influences of intimate partner violence (IPV) among immigrant groups in the United States, particularly South Asians. Using a socioecological framework, this study examined risk and protective factors of IPV among a diverse group of South Asian immigrant survivors of IPV and identified their perceived need for services. METHOD: Sixteen South Asian immigrant survivors were recruited from New York; Maryland; Virginia; and Washington, DC, using a snowball sampling method...
May 24, 2018: Cultural Diversity & Ethnic Minority Psychology
https://www.readbyqxmd.com/read/29791813/higher-lung-cancer-incidence-in-young-women-than-young-men-in-the-united-states
#3
Ahmedin Jemal, Kimberly D Miller, Jiemin Ma, Rebecca L Siegel, Stacey A Fedewa, Farhad Islami, Susan S Devesa, Michael J Thun
BACKGROUND: Previous studies showed a higher incidence of lung cancer among young women than among young men in the United States. Whether this pattern has continued in contemporary birth cohorts and, if so, whether it can be fully explained by sex differences in smoking behaviors are unknown. METHODS: We examined the nationwide population-based incidence of lung cancer according to sex, race or ethnic group, age group (30 to 34, 35 to 39, 40 to 44, 45 to 49, and 50 to 54 years), year of birth (1945 to 1980), and calendar period of diagnosis (1995-1999, 2000-2004, 2005-2009, and 2010-2014), and we calculated female-to-male incidence rate ratios...
May 24, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29790517/the-rotation-vibration-spectrum-of-methyl-fluoride-from-first-principles
#4
Alec Owens, Andrey Yachmenev, Jochen Küpper, Sergei N Yurchenko, Walter Thiel
Accurate ab initio calculations on the rotation-vibration spectrum of methyl fluoride (CH3F) are reported. A new nine-dimensional potential energy surface (PES) and dipole moment surface (DMS) have been generated using high-level electronic structure methods. Notably, the PES was constructed from explicitly correlated coupled cluster calculations with extrapolation to the complete basis set limit and considered additional energy corrections to account for core-valence electron correlation, higher-order coupled cluster terms beyond perturbative triples, scalar relativistic effects, and the diagonal Born-Oppenheimer correction...
May 23, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29790483/the-effect-of-changing-one-s-country-of-residence-on-the-decision-to-become-an-organ-donor-the-experience-of-religious-immigrant-women-living-in-sweden
#5
Ferid Krupić, Sahmir Šadić, Svemir Čustović, Mahir Jašarević, Mirsad Fazlić, Kristian Samuelsson
Aim To explore and elucidate women's knowledge of and willingness to take part in organ donation, and to explore if their opinions were changed by coming to Sweden. Methods The study was designed as a qualitative study using data from interviews with women from Bosnia and Herzegovina, Macedonia, Croatia and Kosovo. The inclusion criteria were women who were immigrants in Sweden and have lived in Sweden for more than 10 years. Five groups including forty-five women were invited to participate in the study and 39 agreed...
August 1, 2018: Medicinski Glasnik
https://www.readbyqxmd.com/read/29789953/update-on-tick-borne-bacterial-diseases-in-travelers
#6
REVIEW
Carole Eldin, Philippe Parola
PURPOSE OF REVIEW: Ticks are the second most important vectors of infectious diseases after mosquitoes worldwide. The growth of international tourism including in rural and remote places increasingly exposes travelers to tick bite. Our aim was to review the main tick-borne infectious diseases reported in travelers in the past 5 years. RECENT FINDINGS: In recent years, tick-borne bacterial diseases have emerged in travelers including spotted fever group (SFG) rickettsioses, borrelioses, and diseases caused by bacteria of the Anaplasmataceae family...
May 22, 2018: Current Infectious Disease Reports
https://www.readbyqxmd.com/read/29789947/relationship-between-brain-function-aeeg-and-brain-structure-mri-and-their-predictive-value-for-neurodevelopmental-outcome-of-preterm-infants
#7
Britta Hüning, Tobias Storbeck, Nora Bruns, Frauke Dransfeld, Julia Hobrecht, Julia Karpienski, Selma Sirin, Bernd Schweiger, Christel Weiss, Ursula Felderhoff-Müser, Hanna Müller
To improve the prediction of neurodevelopmental outcome in very preterm infants, this study used the combination of amplitude-integrated electroencephalography (aEEG) within the first 72 h of life and cranial magnetic resonance imaging (MRI) at term equivalent age. A single-center cohort of 38 infants born before 32 weeks of gestation was subjected to both investigations. Structural measurements were performed on MRI. Multiple regression analysis was used to identify independent factors including functional and structural brain measurements associated with outcome at a corrected age of 24 months...
May 22, 2018: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29789346/maternal-polycystic-ovarian-syndrome-and-offspring-growth-the-upstate-kids-study
#8
Griffith A Bell, Rajeshwari Sundaram, Sunni L Mumford, Hyojun Park, Miranda Broadney, James L Mills, Erin M Bell, Edwina H Yeung
BACKGROUND: Polycystic ovarian syndrome (PCOS) is the most common cause of female infertility and is associated with higher levels of circulating androgens. Exposure to higher levels of androgens in utero may be a risk factor for obesity among children of women with PCOS. METHODS: We examined whether maternal PCOS was associated with differences in offspring growth and obesity in the Upstate KIDS study, a prospective cohort study of infants born in New York State (excluding New York City) oversampled for fertility treatments and multiple births...
May 22, 2018: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/29786689/gridded-birth-and-pregnancy-datasets-for-africa-latin-america-and-the-caribbean
#9
W H M James, N Tejedor-Garavito, S E Hanspal, A Campbell-Sutton, G M Hornby, C Pezzulo, K Nilsen, A Sorichetta, C W Ruktanonchai, A Carioli, D Kerr, Z Matthews, A J Tatem
Understanding the fine scale spatial distribution of births and pregnancies is crucial for informing planning decisions related to public health. This is especially important in lower income countries where infectious disease is a major concern for pregnant women and new-borns, as highlighted by the recent Zika virus epidemic. Despite this, the spatial detail of basic data on the numbers and distribution of births and pregnancies is often of a coarse resolution and difficult to obtain, with no co-ordination between countries and organisations to create one consistent set of subnational estimates...
May 22, 2018: Scientific Data
https://www.readbyqxmd.com/read/29786651/clinical-efficacy-associated-with-enhanced-antioxidant-enzyme-activities-of-silver-nanoparticles-biosynthesized-using-moringa-oleifera-leaf-extract-against-cutaneous-leishmaniasis-in-a-murine-model-of-leishmania-major
#10
Manal El-Khadragy, Ebtesam M Alolayan, Dina M Metwally, Mohamed F Serag El-Din, Sara S Alobud, Nour I Alsultan, Sarah S Alsaif, Manal A Awad, Ahmed E Abdel Moneim
Leishmaniasis is one of the most significant vector-borne syndromes of individuals. This parasitic infection can be affected by many species of Leishmania, most of which are zoonotic. Natural products have made and are continuing to make important contributions to the search for new antileishmanial agents. The use of plants in the production assembly of silver nanoparticles has drawn attention because of its rapid, eco-friendly, non-pathogenic, economical protocol and provides a single step technique for the biosynthetic process...
May 22, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29786583/incidence-and-risk-factors-of-spina-bifida-in-children
#11
Mariana O Ryznychuk, Mariana I Kryvchanska, Irina V Lastivka, Roman Ye Bulyk
OBJECTIVE: Introduction: The pathogenesis of spina bifida depends on time, region, race and ethnicity. It is found in 4.7 per 10.000 of live born children worldwide. The aim: The incidence in children of Northern Bukovina was analyzed. The spina bifida incidence for 2007-2016 in this region, as well as, compared to some countries according to EUROCAT data was studied. PATIENTS AND METHODS: Materials and methods: A retrospective study to analyze the risk factors for spina bifida was carried out...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29785519/threshold-dynamics-of-a-temperature-dependent-stage-structured-mosquito-population-model-with-nested-delays
#12
Xiunan Wang, Xingfu Zou
Mosquito-borne diseases remain a significant threat to public health and economics. Since mosquitoes are quite sensitive to temperature, global warming may not only worsen the disease transmission case in current endemic areas but also facilitate mosquito population together with pathogens to establish in new regions. Therefore, understanding mosquito population dynamics under the impact of temperature is considerably important for making disease control policies. In this paper, we develop a stage-structured mosquito population model in the environment of a temperature-controlled experiment...
May 21, 2018: Bulletin of Mathematical Biology
https://www.readbyqxmd.com/read/29783963/he-tamariki-kokoti-tau-tackling-preterm-a-data-linkage-methodology-to-explore-the-clinical-care-pathway-in-preterm-deliveries
#13
Sara Filoche, Fiona Cram, Angela Beard, Dalice Sim, Stacie Geller, Liza Edmonds, Bridget Robson, Beverley Lawton
BACKGROUND: Significant health inequities exist around maternal and infant health for Māori, the indigenous people of Aotearoa New Zealand - and in particular around a premature (preterm) delivery. Māori babies are more likely to be born preterm (8.1%, compared to an overall rate of 7.4%) and they are more likely to have a preterm death. An essential part of redressing these disparities is to examine the clinical care pathway and outcomes associated with preterm deliveries. This paper describes a protocol utilising national and local health collections to enable such a study...
May 21, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29780749/-rhipicephalus-bursa-sialotranscriptomic-response-to-blood-feeding-and-babesia-ovis-infection-identification-of-candidate-protective-antigens
#14
Sandra Antunes, Joana Couto, Joana Ferrolho, Fábio Rodrigues, João Nobre, Ana S Santos, M Margarida Santos-Silva, José de la Fuente, Ana Domingos
Ticks are among the most prevalent blood-feeding arthropods, and they act as vectors and reservoirs for numerous pathogens. Sialotranscriptomic characterizations of tick responses to blood feeding and pathogen infections can offer new insights into the molecular interplay occurring at the tick-host-pathogen interface. In the present study, we aimed to identify and characterize Rhipicephalus bursa salivary gland (SG) genes that were differentially expressed in response to blood feeding and Babesia ovis infection...
2018: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29779481/absorptive-and-secretory-transport-of-selected-artemisinin-derivatives-across-caco-2-cell-monolayers
#15
Jaco Heyns, Clarissa Willers, Richard K Haynes, Ho N Wong, Josias H Hamman, Chrisna Gouws
Malaria continues to be a major health concern and affects more than 200 million people a year. Drugs currently used for treatment of malaria are increasingly rendered ineffectual by the ongoing emergence of parasite resistance. For any new drugs, however, knowledge of their membrane permeability is an essential pre-requisite for eventual use. Treatment failure and emergence of resistance can occur as a result of reduced availability of the drug at the desired site of action. Cell-based permeability assays such as Caco-2 cell monolayers serve as a model for predicting drug absorption and efflux, and provide an estimate of drug bioavailability...
May 18, 2018: Current Drug Delivery
https://www.readbyqxmd.com/read/29778634/genetic-characterization-of-anaplasma-marginale-strains-from-tunisia-using-single-and-multiple-gene-typing-reveals-novel-variants-with-an-extensive-genetic-diversity
#16
Mourad Ben Said, Alaa Ben Asker, Hanène Belkahia, Raoua Ghribi, Rachid Selmi, Lilia Messadi
Anaplasma marginale, which is responsible for bovine anaplasmosis in tropical and subtropical regions, is a tick-borne obligatory intraerythrocytic bacterium of cattle and wild ruminants. In Tunisia, information about the genetic diversity and the phylogeny of A. marginale strains are limited to the msp4 gene analysis. The purpose of this study is to investigate A. marginale isolates infecting 16 cattle located in different bioclimatic areas of northern Tunisia with single gene analysis and multilocus sequence typing methods on the basis of seven partial genes (dnaA, ftsZ, groEL, lipA, secY, recA and sucB)...
May 12, 2018: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/29777898/a-survey-of-health-professionals-views-on-acceptable-gestational-age-and-termination-of-pregnancy-for-fetal-anomaly
#17
Lisa Crowe, Ruth H Graham, Stephen C Robson, Judith Rankin
Termination of pregnancy for fetal anomaly is legal in the UK with no upper limit, if two doctors, in good faith, agree "there is a substantial risk that if the child were born it would suffer from such physical or mental abnormalities as to be seriously handicapped". This is Clause E of the Human Fertlisation and Embryology Act. The most commonly sighted Clause is C, which states "the pregnancy has not exceeded its twenty-fourth week and that the continuance of the pregnancy would involve risk, greater than if the pregnancy were terminated, of injury to the physical or mental health of the pregnant woman"...
May 16, 2018: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/29776787/the-value-of-peripheral-perfusion-index-measurements-for-early-detection-of-critical-cardiac-defects
#18
Ozgun Uygur, Ozge Altun Koroglu, Erturk Levent, Merve Tosyali, Mete Akisu, Mehmet Yalaz, Nilgun Kultursay
BACKGROUND: Approximately 25% of congenital heart diseases (CHD) are estimated to be critical and require an intervention. In this study, we aimed to investigate the additional value of peripheral perfusion index (PPI) measurements to pulse oximetry screening for critical CHD (CCHD). METHODS: Infants born at Ege University Hospital between May 2013 and September 2015 were prospectively included in the study. In addition to physical examination, pre- and postductal oxygen saturations and PPI values were measured with a new generation pulse oximeter before discharge from the hospital...
April 12, 2018: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/29776375/range-wide-genetic-analysis-of-dermacentor-variabilis-and-its-francisella-like-endosymbionts-demonstrates-phylogeographic-concordance-between-both-taxa
#19
Emily L Kaufman, Nathan E Stone, Glen A Scoles, Crystal M Hepp, Joseph D Busch, David M Wagner
BACKGROUND: The American dog tick, Dermacentor variabilis, is an important vector of pathogens to humans, wildlife and domestic animals in North America. Although this tick species is widely distributed in the USA and Canada, knowledge of its range-wide phylogeographic patterns remains incomplete. METHODS: We carried out a phylogenetic analysis of D. variabilis using samples collected from 26 USA states and five Canadian provinces. Tick samples (n = 1053 in total) originated from two main sources: existing archives (2000-2011), and new collections made from 2012 to 2013...
May 18, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29774519/zika-virus-baculovirus-expressed-virus-like-particles-induce-neutralizing-antibodies-in-mice
#20
Shiyu Dai, Tao Zhang, Yanfang Zhang, Hualin Wang, Fei Deng
The newly emerged mosquito-borne Zika virus (ZIKV) strains pose a global challenge owing to its ability to cause microcephaly and neurological disorders. Several ZIKV vaccine candidates have been proposed, including inactivated and live attenuated virus vaccines, vector-based vaccines, DNA and RNA vaccines. These have been shown to be efficacious in preclinical studies in mice and nonhuman primates, but their use will potentially be a threat to immunocompromised individuals and pregnant women. Virus-like particles (VLPs) are empty particles composed merely of viral proteins, which can serve as a safe and valuable tool for clinical prevention and treatment strategies...
May 17, 2018: Virologica Sinica
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