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Per oral endoscopic myotomy

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https://www.readbyqxmd.com/read/29759157/per-oral-endoscopic-myotomy-short-term-outcomes-are-good-but-the-long-term-results-are-what-count
#1
EDITORIAL
Joel E Richter
No abstract text is available yet for this article.
June 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29748143/the-investigation-and-treatment-of-diabetic-gastroparesis
#2
REVIEW
Mohit Kumar, Adam Chapman, Saad Javed, Uazman Alam, Rayaz A Malik, Shazli Azmi
PURPOSE: This review provides an update on the investigations and treatment options for gastroparesis. METHODS: A comprehensive literature search of Medline, PubMed, Embase and OVID was conducted which included all systematic reviews and research articles that focused on the diagnosis, investigations and management diabetic gastroparesis. FINDINGS: Dietary modifications and pharmacologic treatment with prokinetics to increase gastric motility form the mainstay of treatment...
May 7, 2018: Clinical Therapeutics
https://www.readbyqxmd.com/read/29742979/electrical-stimulation-of-the-lower-esophageal-sphincter-to-treat-gastroesophageal-reflux-after-poem
#3
Erwin Rieder, Matthias Paireder, Ivan Kristo, Katrin Schwameis, Sebastian F Schoppmann
As per-oral endoscopic myotomy (POEM) is not followed by any anti-reflux procedure, a common concern is the risk of postoperative gastro-esophageal reflux disease (GERD). Electrical stimulation of the lower esophageal sphincter (LES-EST) could be an option for post-POEM GERD. A 68-year old male obese patient underwent successful POEM but developed GERD not responsive to proton pump inhibitors. Consecutively, the patient had implanted an electrical LES stimulation device, consisting of bipolar LES-electrodes connected to a subcutaneous pulse generator...
May 1, 2018: Surgical Innovation
https://www.readbyqxmd.com/read/29712595/laparoscopic-heller-myotomy-versus-per-oral-endoscopic-myotomy-evidence-based-approach-to-the-treatment-of-esophageal-achalasia
#4
Francisco Schlottmann, Marco G Patti
Esophageal achalasia is a rare disorder characterized by a failure of the lower esophageal sphincter to relax during swallowing, combined with aperistalsis of the esophageal body. Treatment is not curative, but aims to eliminate the outflow resistance caused by the nonrelaxing lower esophageal sphincter. Current evidence suggests that both laparoscopic Heller myotomy and per oral endoscopic myotomy (POEM) are very effective in the relief of symptoms in patients with achalasia. Specifically, for type III achalasia, POEM may achieve higher success rates...
April 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/29687294/endoscopic-therapies-for-gastroparesis
#5
REVIEW
Andrew Su, Jeffrey L Conklin, Alireza Sedarat
PURPOSE OF REVIEW: Gastroparesis remains a difficult-to-treat disease with limited therapeutic options. Though patients often have a common syndrome of stereotypic symptoms, the underlying pathophysiology is heterogeneous, often leading to variable treatment responses. Due to limitations in medical and surgical therapies, endoscopic options have been increasingly explored. These options can be broadly categorized into pyloric-directed therapy, non-pyloric-directed therapy, and nutritional support...
April 23, 2018: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/29684386/valuing-innovative-endoscopic-techniques-per-oral-endoscopic-myotomy-for-the-management-of-achalasia
#6
Eric D Shah, Andrew C Chang, Ryan Law
BACKGROUND AND AIMS: Unclear reimbursement for new and innovative endoscopic procedures can limit adoption in clinical practice despite effectiveness in clinical trials. The aim of this study was to determine maximum cost-effective reimbursement for per-oral endoscopic myotomy (POEM) in treating achalasia. METHODS: We constructed a decision analytic model assessing POEM versus laparoscopic Heller myotomy with Dor fundoplication (LHM) in managing achalasia from a payer perspective over a 1-year time horizon...
April 20, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29608432/treatment-of-achalasia-with-per-oral-endoscopic-myotomy-analysis-of-50-consecutive-patients
#7
Erica D Kane, David J Desilets, Donna Wilson, Marc Leduc, Vikram Budhraja, John R Romanelli
BACKGROUND: Peroral endoscopic myotomy (POEM) has become an acceptable incisionless treatment for achalasia based on encouraging outcomes in multiple series worldwide. This report reflects our early experience. METHODS: Data were collected prospectively on all patients undergoing POEM between June 2011 and April 2016 under IRB approval. Diagnosis of achalasia was confirmed by standard preoperative work-up. Primary outcome was symptom relief, measured by Eckardt score...
April 2, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29571969/efficacy-of-anterior-versus-posterior-per-oral-endoscopic-myotomy-for-treating-achalasia-a-randomized-prospective-study
#8
Yuyong Tan, Liang Lv, Xuehong Wang, Hongyi Zhu, Yi Chu, Min Luo, Chenjie Li, Hejun Zhou, Jirong Huo, Deliang Liu
BACKGROUND AND AIMS: Per-oral endoscopic myotomy (POEM) has been demonstrated to be safe and effective for treating achalasia. Two approaches-anterior myotomy and posterior myotomy-are used during POEM. However, little is known about the comparison between the two different approaches. The objective of the study is to compare the safety and short-term efficacy of the 2 approaches for treating achalasia. METHODS: From October 2015 to December 2016, 63 consecutive patients with achalasia without prior treatment or sigmoid-type esophagus were prospectively recruited...
March 20, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29571778/retraction-notice-to-long-term-outcomes-of-per-oral-endoscopic-myotomy-in-patients-with-achalasia-with-a-minimum-follow-up-of-2-years-an-international-multicenter-study-ymge-85-2017-927-933
#9
Saowanee Ngamruengphong, Haruhiro Inoue, Philip Wai-Yan Chiu, Hon Chi Yip, Amol Bapaye, Michael Ujiki, Lava Patel, Pankaj N Desai, Bu Hayee, Amyn Haji, Vivien Wai-Yin Wong, Silvana Perretta, Shivangi Dorwat, Mathieu Pioche, Sabine Roman, Jérôme Rivory, François Mion, Thierry Ponchon, Aurélien Garros, Jun Nakamura, Yoshitaka Hata, Valerio Balassone, Manabu Onimaru, Gulara Hajiyeva, Amr Ismail, Yen-I Chen, Majidah Bukhari, Yamile Haito-Chavez, Vivek Kumbhari, Roberta Maselli, Alessandro Repici, Mouen A Khashab
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted due to overlapping/duplicate material. Data from some patients from this study have previously been published in other journals without cross-referencing. Twenty patients overlap with a paper by Kumbhari et al.1 Thirty-five patients overlap with the study by Ngamruengphong et al.2 .
April 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29488045/bladder-pressure-monitoring-and-co-2-gas-related-adverse-events-during-per-oral-endoscopic-myotomy
#10
Mari Yamashita-Ichimura, Emiko Toyama, Makoto Sasoh, Hironari Shiwaku, Kanefumi Yamashita, Yuichi Yamashita, Ken Yamaura
Per-oral endoscopic myotomy (POEM) is a minimally invasive treatment for esophageal achalasia. However, POEM has the potential risk of inducing carbon dioxide (CO2 ) gas-related adverse events, such as pneumoperitoneum, pneumomediastinum, and pneumothorax. The aim of this study was to evaluate the usability of bladder pressure monitoring as an index of CO2 gas-related pneumoperitoneum. The monitoring of bladder pressure and lung compliance and the incidence of iatrogenic pneumoperitoneum were retrospectively studied in 20 patients who underwent POEM between June 2013 and March 2015...
February 27, 2018: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/29468376/gastric-per-oral-endoscopic-myotomy-g-poem-for-the-treatment-of-refractory-gastroparesis-early-experience
#11
Zubair Malik, Rahul Kataria, Rani Modayil, Adam C Ehrlich, Ron Schey, Henry P Parkman, Stavros N Stavropoulos
BACKGROUND: Gastric per oral endoscopic myotomy (G-POEM) of the pylorus is a technique that is recently being used to treat gastroparesis. Our aim was to report our experience in performing G-POEM for refractory gastroparesis of different etiologies and determine symptom improvement. METHODS: Thirteen patients undergoing G-POEM are reported. Pre- and post-procedure gastric emptying study (GES) and PAGI-SYM for symptom severity were obtained. Patients underwent G-POEM by creating a submucosal tunnel starting in the greater curvature of the distal antrum and extending it to the beginning of the duodenal bulb, followed by a full thickness pyloromyotomy...
February 22, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29452437/successful-treatment-of-giant-esophageal-diverticulum-by-per-oral-endoscopic-myotomy
#12
Chuncheng Wu, Qiongying Zhang, Wei Liu, Bing Hu
No abstract text is available yet for this article.
May 2018: Endoscopy
https://www.readbyqxmd.com/read/29435752/gastric-per-oral-endoscopic-myotomy-for-refractory-gastroparesis-a-detailed-description-of-the-procedure-our-experience-and-review-of-the-literature
#13
Lianyong Li, Robert Spandorfer, Changmin Qu, Yongtao Yang, Shuwen Liang, Huimin Chen, Hanbing Xue, Qiang Cai
BACKGROUND AND AIMS: Gastric per-oral endoscopic myotomy (G-POEM) was introduced four years ago as an investigational procedure for refractory gastroparesis. The safety and efficacy were currently evaluated. With our recent studies on G-POEM, we share our experience and knowledge through the discussion of a detailed description of the procedure and review of the literature. To our knowledge, this is the first systemic review on this new therapeutic endoscopic procedure. METHODS: The indications and contraindications, various aspects of the procedure, and efficacy assessment are discussed based on our experience and current available data...
February 12, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29410304/life-after-per-oral-endoscopic-myotomy-long-term-outcomes-of-quality-of-life-and-their-association-with-eckardt-scores
#14
Yaseen B Perbtani, Lazarus K Mramba, Dennis Yang, Jorge Suarez, Peter V Draganov
BACKGROUND AND AIMS: The clinical efficacy of per-oral endoscopic myotomy (POEM) has been commonly established by reduction in the Eckardt score (<3) after the procedure. However, achalasia can lead to significant impairment in the patient's quality of life that may go beyond the 4 classic achalasia symptoms as measured by the Eckardt score. The aims of our study were to evaluate the effect of POEM on short-term and long-term health-related quality of life (HRQOL) and to assess the association between HRQOL and Eckardt scores...
February 2, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29410262/laparoscopic-heller-myotomy-vs-per-oral-endoscopic-myotomy-patient-reported-outcomes-at-a-single-institution
#15
Andrew N Hanna, Jashodeep Datta, Sara Ginzberg, Kevin Dasher, Gregory G Ginsberg, Daniel T Dempsey
BACKGROUND: Although laparoscopic Heller myotomy (LHM) has been the standard of care for achalasia, per oral endoscopic myotomy (POEM) has gained popularity as a viable alternative. This retrospective study aimed to compare patient-reported outcomes between LHM and POEM in a consecutive series of achalasia patients with more than 1 year of follow-up. STUDY DESIGN: We reviewed demographic and procedure-related data for patients who underwent either LHM or POEM for achalasia between January 2011 and May 2016...
April 2018: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/29383495/per-oral-endoscopic-myotomy-for-esophageal-achalasia-in-a-case-of-allgrove-syndrome
#16
Jun Nakamura, Takuto Hikichi, Haruhiro Inoue, Ko Watanabe, Hitomi Kikuchi, Tadayuki Takagi, Rei Suzuki, Mitsuru Sugimoto, Naoki Konno, Yuichi Waragai, Hiroyuki Asama, Mika Takasumi, Yuki Sato, Hiroki Irie, Katsutoshi Obara, Hiromasa Ohira
Allgrove syndrome, also known as Triple A syndrome, is a rare autosomal recessive genetic disease characterized by three signs: esophageal achalasia, adrenocorticotropic hormone refractoriness, and alacrima. A 31-year-old male presented to our hospital for treatment of difficulty swallowing caused by esophageal achalasia. Because he had complicating alacrima, a neurologic disease, and a family history of consanguineous marriage, a genetic neurologic disease was suspected. Then, a mutation in the achalasia-addisonianism-alacrima syndrome gene was identified...
January 30, 2018: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/29380066/outcomes-and-quality-of-life-assessment-after-per-oral-endoscopic-myotomy-poem-performed-in-the-endoscopy-unit-with-trainees
#17
Sunil Dacha, Lei Wang, Xaioyu Li, Yueping Jiang, George Philips, Steven A Keilin, Field F Willingham, Qiang Cai
BACKGROUND: Per oral endoscopic myotomy (POEM) has emerged as a promising option for the treatment of achalasia. This study assessed POEM training process, outcomes, and improvement in quality of life after POEM performed by an interventional endoscopist (mentor) with trainees. METHODS: We performed a retrospective review of data for patients who underwent POEM with involvement of trainees. Trainees were trained in performing mucosotomy, submucosal dissection, creating submucosal tunnel, identifying gastroesophageal junction, myotomy, and closure of mucosal incision in a step-by-step fashion...
January 29, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29377271/-management-of-achalasia-cardia-expert-consensus-statements
#18
REVIEW
Mohan Ramchandani, D Nageshwar Reddy, Zaheer Nabi, Radhika Chouhan, Amol Bapaye, Shobhna Bhatia, Nilay Mehta, Pankaj Dhawan, Adarsh Chaudhary, Uday Ghoshal, Mathew Philip, Horst Neuhaus, Jacques Deviere, Haruhiro Inoue
Achalasia cardia (AC) is a frequently encountered motility disorder of the esophagus resulting from an irreversible degeneration of neurons. Treatment modalities are palliative in nature and there is no curative treatment available for AC as of now. Significant advancements have been made in the management of AC over last decade. The introduction of high resolution manometry (HRM) and per-oral endoscopic myotomy (POEM) have strengthened the diagnostic and therapeutic armamentarium of AC. HRM allows for the characterization of the type of achalasia which in turn has important therapeutic implications...
January 29, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29353638/submucosal-surgery-novel-interventions-in-the-third-space
#19
REVIEW
Ezra N Teitelbaum, Lee L Swanstrom
Traditional surgeries involve accessing body cavities, such as the abdomen and thorax, via incisions that divide skin and muscle. These operations result in postoperative pain and convalescence, and a risk of complications such as wound infection and hernia. The development of flexible endoscopy allowed diseases as varied as gastrointestinal bleeding and colon adenomas to be treated without incisions, but this technique is restricted by its endoluminal nature. A novel category of surgical endoscopic procedures has recently been developed that uses flexible endoscopic techniques to enter and access the submucosa of the gastrointestinal tract...
February 2018: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29349541/per-oral-endoscopic-myotomy-early-experience-and-safety-of-a-multispecialty-approach
#20
Evgeny V Arshava, Raffaele J Marchigiani, Henning Gerke, Rami El Abiad, Ronald J Weigel, Kalpaj R Parekh, John Keech
BACKGROUND: Per oral endoscopic myotomy (POEM) has gained increasing popularity for treating achalasia. A multidisciplinary approach may allow safe and early adoption of POEM into clinical practice. MATERIALS AND METHODS: We performed a retrospective review of our initial POEM cases. All procedures were performed by a team of interventional gastroenterologist and thoracic surgeon. We analyzed demographics, comorbidities, achalasia subtypes, length of hospital stay, duration of surgery, morbidity, mortality, length of myotomy, preoperative and postoperative Eckardt scores...
January 18, 2018: Surgical Endoscopy
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