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Necrotizing sinus

Anisha George, Dincy Peter, Susanne Pulimood, Marie Therese Manipadam, Biju George, M J Paul, Jinu Kurian Thomas
No abstract text is available yet for this article.
September 2016: Indian Dermatology Online Journal
Alina Tanase, Anca Colita, Gabriel Ianosi, Daniela Neagoe, Daciana Elena Branisteanu, Daniela Calina, Anca Oana Docea, Aristidis Tsatsakis, Simona Laura Ianosi
Fusarium infection is a severe fungal infection caused by fungi of the genus Fusarium. It most commonly occurs in immunocompromised patients with malignant hematological comorbidities or secondary to hematopoietic stem cell transplant. The classical route of contamination is through inhalation but infection may also occur through contiguity with a skin lesion. This report describes the case of a 24-year-old woman who developed graft-vs.-host disease (GVHD) at 220 days after receiving an allogeneic stem cell transplant from a sibling donor for Hodgkin disease...
October 2016: Experimental and Therapeutic Medicine
Eman A El Ashiry, Najat M Farsi, Sawsan T Abuzeid, Mohamed M El Ashiry, Hammam A Bahammam
OBJECTIVES: The treatment of immature necrotic teeth with apical periodontitis presents challenges in endodontic and pediatric dentistry. Revascularization is a recent treatment for such cases as an alternative to conventional apexification. The purpose is to examine the effect of a pulpal revascularization procedure on immature necrotic teeth with apical periodontitis. STUDY DESIGN: Twenty patients were enrolled for pulp revascularization procedure by root canal disinfection using a triple antibiotic mixture for 1-2 weeks, followed by creating a blood clot, sealing the root canal orifice using white mineral trioxide aggregate and a coronal seal of composite resin...
2016: Journal of Clinical Pediatric Dentistry
Michael R Preusch, Jonas Rusnak, Kathrin Staudacher, Carolin Mogler, Lorenz Uhlmann, Philipp Sievers, Florian Bea, Hugo A Katus, Erwin Blessing, Ingo Staudacher
OBJECTIVE: There is increasing evidence supporting the role of platelets in atherosclerotic vascular disease. The G-protein-coupled receptor P2Y12 is a central mediator of platelet activation and aggregation but has also been linked to platelet-independent vascular disease. Ticagrelor is an oral P2Y12 antagonist that is used as a standard treatment in patients after acute myocardial infarction. However, the effects of ticagrelor on advanced atherosclerosis have not been investigated. MATERIALS AND METHODS: Twenty-week-old apolipoprotein-E-deficient mice received standard chow or standard chow supplemented with 0...
2016: Drug Design, Development and Therapy
Harris Sultan, Amina Malik, Helen K Li, Patricia Chévez-Barrios, Andrew G Lee
A 50 year-old man on immunosuppressive agents presented with left eye vision loss, periorbital swelling, pain, and ophthalmoplegia. The patient was clinically found to have a central retinal artery and vein occlusion. A CT scan was performed which demonstrated intraorbital fat stranding, however the patient lacked sinus disease. The etiology of the orbital infection was held in question. The area was debrided in the operating room, and the specimen demonstrated group A streptococcal species consistent with necrotizing fasciitis...
August 23, 2016: Ophthalmic Plastic and Reconstructive Surgery
P Lohneis, A Nogai, S M Niehues, K Jöhrens, I Anagnostopoulos
During the preoperative diagnostics of an 80-year-old male patient prior to a planned endarterectomy, an unclear space-occupying lesion was detected in the right nasopharyngeal cavity. It proved to be a dense soft tissue space-occupying lesion of the right maxillary sinus. The histological investigations revealed a partially necrotically decomposed malignant tumor below normal respiratory mucosa free from dysplasia. This case demonstrates the difficulties in differential diagnostics, particularly involving (aberrant) expression of cytokeratin...
August 17, 2016: Der Pathologe
Nima D Sarmast, Howard H Wang, Nikolaos K Soldatos, Nikola Angelov, Samuel Dorn, Raymond Yukna, Vincent J Iacono
BACKGROUND: While retrograde peri-implantitis is not a common sequela of dental implant surgery, its prevalence has been reported to be 0.26% in the literature. The incidence of retrograde peri-implantitis is reported to increase to 7.8% when teeth adjacent to the implant site have a previous history of root canal therapy, and it is correlated with the distance between the implant and the adjacent tooth, and/or the time from the endodontic treatment of the adjacent tooth to implant placement...
August 6, 2016: Journal of Periodontology
Takenori Inomata, Miki Honda, Akira Murakami
PURPOSE: To describe atypical varicella zoster virus (VZV) retinitis in a patient with Good syndrome. METHODS: A 63-year-old patient with Good syndrome presented with bilateral necrotizing retinitis starting from the posterior pole. He had a history of thymoma status post thymectomy 4 years previously, left-sided sinusitis, and recent pulmonary aspergillosis. Qualitative PCR was performed on aqueous fluid. RESULTS: Immunological investigations revealed reduced levels of CD4(+) T cells and immunoglobulins...
August 5, 2016: Ocular Immunology and Inflammation
Mohammad Mhd Nader Aldakak, Ismail Davut Capar, Mohammad Salem Rekab, Souad Abboud
UNLABELLED: An 11-year-old female patient was referred with a chief complaint of pain in the right mandibular second premolar. Clinical and radiographic examinations showed secondary caries under an old composite restoration, a negative response to a pulp test and an immature root with an open apex. After root canal cleaning and shaping, bleeding was invoked in the canal up to 2 mm short of the cemento-enamel junction (CEJ). After 10 min to allow clotting at this level, a plug of Biodentine was placed over the blood clot and the tooth was temporized with glass ionomer cement...
2016: Iranian Endodontic Journal
Yuzhou Gui, Sheng Yao, Hong Yan, Liang Hu, Chengyin Yu, Fei Gao, Cong Xi, Huihui Li, Yang Ye, Yiping Wang
AIMS: Atherosclerosis is the most common cause of cardiovascular diseases, such as myocardial infarction and stroke. We hypothesized that nagilactone B (NLB), a small molecule extracted from the root bark of Podocarpus nagi (Podocarpaceae), suppresses atherosclerosis in an atherosclerotic mouse model. METHODS AND RESULTS: Male apoE-deficient mice on C57BL/6J background received NLB (10 and 30 mg/kg) for 12 weeks. Compared with the model group, NLB treatment (10 and 30 mg/kg) significantly reduced en face lesions of total aorta areas...
October 2016: Cardiovascular Research
Azhar Iqbal
INTRODUCTION: The endodontic failure is a common problem in dentistry. The success of endodontic and re-endodontic treatment depends on many factors. These includes periodontal disease, root fractures, residual necrotic pulp tissue, presence of peri-radicular infection, broken instruments, mechanical perforations, root canal underfillings, root canal overfillings, missed canals or unfilled canals. AIM: The present research was aimed at evaluating the different factors responsible for endodontic treatment failure in permanent dentitions of the patients...
May 2016: Journal of Clinical and Diagnostic Research: JCDR
Abigail H M Morbi, Ian M Nordon
PURPOSE: This case highlights the importance of timely diagnosis and management of acute mesenteric ischaemia and illustrates the compensatory mechanisms of the mesenteric vasculature. CASE REPORT: A 53-year-old female presented with fever, abdominal pain, and vomiting. The patient had no risk factors for atherosclerosis and was a non-smoker in sinus rhythm with no history of coagulopathy. She was initially treated for viral gastroenteritis. Due to lack of clinical improvement and a rising C-Reactive Protein (416), a CT scan was performed...
June 21, 2016: Acta Chirurgica Belgica
S Schöniger, N Roschanski, U Rösler, A Vidovic, M Nowak, O Dietz, M M Wittenbrink, H-A Schoon
Pyogranulomatous rhinitis associated with an algal infection was diagnosed in a 25-year-old gelding and a 23-year-old mare had necrotizing sinusitis with intralesional algae and pigmented fungi. Algae were identified immunohistochemically in both cases as Prototheca spp. In the gelding, further characterization by polymerase chain reaction and sequencing revealed that the organism was Prototheca zopfii genotype 2. Fungi from the mare were identified as Pithomyces chartarum by molecular analysis. Prototheca species are achlorophyllous algae and P...
August 2016: Journal of Comparative Pathology
Maria Luisa Fiorella, Matteo Gelardi, Andrea Marzullo, Elena Sabattini, Raffaele Fiorella
Kikuchi-Fujimoto's disease (KFD) is a rare, benign condition characterized by histiocytic necrotizing lymphadenitis predominantly in the cervical region and prolonged fever. It has a higher prevalence in the Japanese and Asian populations although it may be seen in a wide geographic distribution, but rare are the cases reported in Europe. While symptoms resolve spontaneously between 2 weeks and 2 months, complications are described in: CNS, eyes, respiratory tract, kidney and liver. KFD also described an association with systemic lupus erythematosus...
June 17, 2016: European Archives of Oto-rhino-laryngology
Dimitri Widmer, Eva Ziemssen, Benjamin Schade, Eva Kappe, Ferdinand Schmitt, Hermann Kempf, Gudrun Wibbelt
Nine Humboldt penguins ( Spheniscus humboldti ), between 1 and 1.5 years old and kept at Zoo Dresden, developed local and systemic infections with various opportunistic pathogens within a period of 4 months. Affected birds died peracutely without preceding symptoms or showed various clinical signs, including separation from conspecifics, reduced food intake, lethargy, dyspnea, swelling of the salt glands, and ocular discharge. One bird showed central nervous signs, including seizures. Pathologic examination of deceased birds revealed severe necrotizing inflammation of the mucous membranes and deep structures of the glottis, trachea, nasal sinus, and conchae and granulomatous inflammation of the salt glands...
June 2016: Journal of Avian Medicine and Surgery
Robert T Fazzio, Sejal S Shah, Nicole P Sandhu, Katrina N Glazebrook
OBJECTIVES: The purpose of this study was to review the imaging features of idiopathic granulomatous mastitis (IGM) with clinical and pathology correlation. METHODS: With institutional review board (IRB) approval, a retrospective search of the surgical pathology database from January 2000 to July 2015 was performed. Clinical, imaging and histology findings were reviewed. Cases of granulomatous mastitis without a known source, diagnosed with percutaneous or surgical biopsy, were included in our analysis...
August 2016: Insights Into Imaging
Guiping Lan, Bo Huang, Yongfeng Si, Yangda Qin, Zhuoxia Deng, Yong Yang, Ying Qin, Benjian Zhang
OBJECTIVE: To investigate the method of surgical treatment via trans-nasal endoscopic approach in osteoradionecrosis of skull base after radiotherapy for nasopharyngeal carcinoma. METHODS: Fifteen patients with osteoradionecrosis of skull base after radiotherapy for nasopharyngeal carcinoma who underwent operation via trans-nasal endoscopic approach from 2008 to 2013 were retrospectively reviewed. The typical clinical manifestations included headache (NRS 6-9: 11 cases), foul odor (10 cases), epistaxis (4 cases), hearing loss (5 cases, 7 ears), tinnitus (4 cases, 5 ears)...
May 2016: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
Brian Gastman, Ahmed M Hashem, Risal Djohan, Steven Bernard, Mark Hendrickson, Graham Schwarz, Bahar B Gharb, Antonio Rampazzo, Anthony Fernandez, James Zins, Gary S Hoffman, Gaby Doumit, Maria Siemionow, Francis Papay
BACKGROUND: Granulomatosis with polyangiitis (Wegener granulomatosis) is a rare disease that commonly starts in the craniofacial region and can lead to considerable facial disfigurement. Granulomas and vasculitis, however, can involve many other tissues (especially pulmonary and renal). Dermatologic and subcutaneous components can lead to malignant pyoderma. METHODS: The authors describe a unique pathologic condition, where significant Le Fort type trauma was associated with subsequent development of granulomatosis with polyangiitis and malignant pyoderma...
June 2016: Plastic and Reconstructive Surgery
Yukie Abiko
A spontaneous tumor was observed in the maxillary gland of a 12-week-old male BALB/c F1 hybrid mouse. Histopathologically, the tumor invaded both the nasal cavity and maxillary sinus, and ethmoturbinates were destroyed. The majority of the tumor cells had oval nuclei with eosinophilic and vacuolar cytoplasm. Numerous mitotic figures and necrotic foci were also observed throughout the tumor. Immunohistochemically, almost all of the tumor cells were strongly positive for cytokeratin (WSS) and alpha-smooth muscle actin...
April 2016: Journal of Toxicologic Pathology
Y Zhang, T Wang, G-L Liu, J Li, S-Q Gao, L Wan
Facial mucormycosis and extranodal natural killer/T cell lymphoma (NK/TCL) are characterized by facial progressive swelling, ulceration and destruction. Patient one was a 58-year-old woman, who had typical clinical-pathological symptoms of tumor. She was hospitalized in order to remove the tumor. But the diagnosis turned out to be primary mucor infection, which was corrected by positive tissue culture and fungal elements in histology. She was also diagnosed with type 2 diabetes mellitus and acute myelocytic leukemia M2a...
September 2016: Journal de Mycologie Médicale
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