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Gisela Cristiane Miyamoto, Katherinne Ferro Moura Franco, Johanna M van Dongen, Yuri Rafael Dos Santos Franco, Naiane Teixeira Bastos de Oliveira, Diego Diulgeroglo Vicco Amaral, Amanda Nery Castelo Branco, Maria Liliane da Silva, Maurits W van Tulder, Cristina Maria Nunes Cabral
OBJECTIVES: To evaluate the effectiveness and cost-utility of the addition of different doses of Pilates to an advice for non-specific chronic low back pain (NSCLBP) from a societal perspective. DESIGN: Randomised controlled trial with economic evaluation. SETTING: Physiotherapy clinic in São Paulo, Brazil. PARTICIPANTS: 296 patients with NSCLBP. INTERVENTIONS: All patients received advice and were randomly allocated to four groups (n=74 per group): booklet group (BG), Pilates once a week (Pilates group 1, PG1), Pilates twice a week (Pilates group 2, PG2) and Pilates three times a week (Pilates group 3, PG3)...
March 10, 2018: British Journal of Sports Medicine
Karolina Tecza, Jolanta Pamula-Pilat, Joanna Lanuszewska, Dorota Butkiewicz, Ewa Grzybowska
The differences in patients' response to the same medication, toxicity included, are one of the major problems in breast cancer treatment. Chemotherapy toxicity makes a significant clinical problem due to decreased quality of life, prolongation of treatment and reinforcement of negative emotions associated with therapy. In this study we evaluated the genetic and clinical risk factors of FAC chemotherapy-related toxicities in the group of 324 breast cancer patients. Selected genes and their polymorphisms were involved in FAC drugs transport ( ABCB1, ABCC2, ABCG2,SLC22A16 ), metabolism ( ALDH3A1, CBR1, CYP1B1, CYP2C19, DPYD, GSTM1, GSTP1, GSTT1, MTHFR,TYMS ), DNA damage recognition, repair and cell cycle control ( ATM, ERCC1, ERCC2, TP53, XRCC1 )...
February 6, 2018: Oncotarget
Huei-Ting Chien, Florian Pilat, Thomas Griesser, Harald Fitzek, Peter Pölt, Bettina Friedel
After the efficiency of organic photovoltaic (OPV) cells achieved more than 10%, the control of stability and degradation mechanisms of solar cells became a prominent task. The improvement of device efficiency due to incorporation of a hole-transport layer (HTL) in bulk-heterojunction solar cells has been extensively reported. However, the most widely used HTL material, poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) is frequently suspected to be the dominating source for device's instability under environmental conditions...
February 28, 2018: ACS Applied Materials & Interfaces
Colin E Correnti, Mesfin M Gewe, Christopher Mehlin, Ashok D Bandaranayake, William A Johnsen, Peter B Rupert, Mi-Youn Brusniak, Midori Clarke, Skyler E Burke, Willem De Van Der Schueren, Kristina Pilat, Shanon M Turnbaugh, Damon May, Alex Watson, Man Kid Chan, Christopher D Bahl, James M Olson, Roland K Strong
Peptides folded through interwoven disulfides display extreme biochemical properties and unique medicinal potential. However, their exploitation has been hampered by the limited amounts isolatable from natural sources and the expense of chemical synthesis. We developed reliable biological methods for high-throughput expression, screening and large-scale production of these peptides: 46 were successfully produced in multimilligram quantities, and >600 more were deemed expressible through stringent screening criteria...
February 26, 2018: Nature Structural & Molecular Biology
Tatiana Odinets, Yuriy Briskin, Maryan Pityn
PURPOSE: The purpose of this study was to determine the effectiveness of an individualized physical rehabilitation programs aimed at improving respiratory function in women with post-mastectomy syndrome. METHODS: In a randomized controlled trial 50 women with post-mastectomy syndrome were enrolled in the experimental group (EG, n = 25) or the comparison group (CG, n = 25). The program for the EG included: aqua aerobics (i.e. aqua jogging, aqua building, and aqua stretching); conditional swimming; and recreational aerobics...
February 26, 2018: Physiotherapy Theory and Practice
Aatit Paungmali, Leonard Henry Joseph, Khanittha Punturee, Patraporn Sitilertpisan, Ubon Pirunsan, Sureeporn Uthaikhup
OBJECTIVE: The main objective of the study was to measure the levels of plasma β-endorphin (PB) and plasma cortisol (PC) under lumbar core stabilization exercise (LCSE), placebo and control conditions in patients with chronic nonspecific low back pain. METHODS: Twenty-four participants with chronic nonspecific low back pain participated in a randomized, placebo-controlled, crossover design study. There were 3 experimental exercise conditions: control condition (positioning in crook lying and rest), placebo condition (passive cycling in crook lying using automatic cycler), and LCSE on a Pilates device tested with a 48-hour interval between sessions by concealed randomization...
February 17, 2018: Journal of Manipulative and Physiological Therapeutics
Roberta Costa Espíndula, Gabriella Barbosa Nadas, Maria Inês da Rosa, Charlie Foster, Florentino Cardoso de Araújo, Antonio Jose Grande
INTRODUCTION: Breast cancer is the leading type of cancer causing death in women worldwide. The incidence of the disease is expected to grow worldwide due to the aging of the population and risk factors related to lifestyle behaviors. Considering the lifestyle of women with breast cancer before or after surgery, pilates exercise may be a complementary intervention additionally to standard treatment. OBJECTIVE: To analyze the efficacy of pilates compared to other exercises and to no exercise for women with breast cancer diagnosis...
November 2017: Revista da Associação Médica Brasileira
Laís Campos de Oliveira, Raphael Gonçalves de Oliveira, Deise Aparecida de Almeida Pires-Oliveira
BACKGROUND AND PURPOSE: Decreased bone mineral density (BMD) is a common condition in postmenopausal women that can be managed with impact activities. Among the activities studied are the whole-body vibration (WBV) and muscle-strengthening exercises. The purpose of this study was to compare the effects of WBV versus Pilates exercise on BMD in postmenopausal women. METHODS: In this study, 51 postmenopausal women were randomized into 3 groups: vibration (n = 17), Pilates (n = 17), and control (n = 17)...
February 12, 2018: Journal of Geriatric Physical Therapy
Asia V Yates, Ayla A Donlin, George J Beneck, Evan E Schick
No abstract text is available yet for this article.
January 2018: Journal of Bodywork and Movement Therapies
Warrick McNeill, Sally Jones, Suzy Barton
No abstract text is available yet for this article.
January 2018: Journal of Bodywork and Movement Therapies
Keira Byrnes, Ping-Jung Wu, Stephney Whillier
BACKGROUND: Pilates is a system of exercise focusing upon controlled movement, stretching and breathing. Pilates is popular today not only for physical fitness but also for rehabilitation programs. This paper is a review of the literature on the effectiveness of Pilates as a rehabilitation tool in a wide range of conditions in an adult population. METHODS: A systematic literature review was carried out according to the PRISMA guidelines. Electronic databases were searched for cohort studies or randomised controlled trials (RCTs), and inclusion and exclusion criteria were applied...
January 2018: Journal of Bodywork and Movement Therapies
Adi Lausen, Louise Marsland, Samantha Head, Joanna Jackson, Berthold Lausen
BACKGROUND: Urinary incontinence (UI) is a distressing condition affecting at least 5 million women in England and Wales. Traditionally, physiotherapy for UI comprises pelvic floor muscle training, but although evidence suggests this can be effective it is also recognised that benefits are often compromised by patient motivation and commitment. In addition, there is increasing recognition that physical symptoms alone are poor indicators of the impact of incontinence on individuals' lives...
January 12, 2018: BMC Women's Health
Thomas Gstrein, Andrew Edwards, Anna Přistoupilová, Ines Leca, Martin Breuss, Sandra Pilat-Carotta, Andi H Hansen, Ratna Tripathy, Anna K Traunbauer, Tobias Hochstoeger, Gavril Rosoklija, Marco Repic, Lukas Landler, Viktor Stránecký, Gerhard Dürnberger, Thomas M Keane, Johannes Zuber, David J Adams, Jonathan Flint, Tomas Honzik, Marta Gut, Sergi Beltran, Karl Mechtler, Elliott Sherr, Stanislav Kmoch, Ivo Gut, David A Keays
The formation of the vertebrate brain requires the generation, migration, differentiation and survival of neurons. Genetic mutations that perturb these critical cellular events can result in malformations of the telencephalon, providing a molecular window into brain development. Here we report the identification of an N-ethyl-N-nitrosourea-induced mouse mutant characterized by a fractured hippocampal pyramidal cell layer, attributable to defects in neuronal migration. We show that this is caused by a hypomorphic mutation in Vps15 that perturbs endosomal-lysosomal trafficking and autophagy, resulting in an upregulation of Nischarin, which inhibits Pak1 signaling...
January 8, 2018: Nature Neuroscience
Roberta Oliveira Bueno de Souza, Liliane de Faria Marcon, Alex Sandro Faria de Arruda, Francisco Luciano Pontes Junior, Ruth Caldeira de Melo
OBJECTIVE: The present meta-analysis aimed to examine evidence from randomized controlled trials in order to determine the effects of mat Pilates on measures of physical functional performance in the elderly. DESIGN: A search was conducted in the MEDLINE/PubMed, Scopus, Scielo and PEDro databases between February and March 2017. Only RCTs that were written in English; included subjects 60 years-old; utilized mat Pilates exercises; included a comparison (control) group; and reported performance-based measures of physical function (balance, flexibility, muscle strength and cardiorespiratory fitness) were included...
December 27, 2017: American Journal of Physical Medicine & Rehabilitation
Iã Ferreira Miranda, Catiane Souza, Alexandre Tavares Schneider, Leandro Campos Chagas, Jefferson Fagundes Loss
BACKGROUND: There is some evidence in the literature about the effectiveness of the Pilates methods in the low back pain. Moreover, Pilates focus on exercises that empathizes the stability and/or mobility of the spine. Therefore, it is discussed in the literature whether higher levels of stability or mobility of the lumbar spine generates better results, both in performance and rehabilitation for low back pain. OBJECTIVES: Compare the effects of the low back mobility and stability exercises from Pilates Method on low back pain, disability and movement functionality in individuals with non-specific chronic low back pain...
December 8, 2017: Complementary Therapies in Clinical Practice
Rodrigo Luiz Vancini, Angeles Bonal Rosell Rayes, Claudio Andre Barbosa de Lira, Karine Jacon Sarro, Marilia Santos Andrade
OBJECTIVE: To compare the effects of Pilates and walking on quality of life, depression, and anxiety levels. METHODS: Sixty-three overweight/obese participants were randomly divided into: control (n = 20), walking (n = 21), and Pilates (n = 22) groups. Pilates and walking groups attended eight weeks of 60-minute exercise sessions three times per week. Quality of life, depression, and state- and trait-anxiety levels were evaluated before and after eight weeks of training...
December 2017: Arquivos de Neuro-psiquiatria
Irimia Mollinedo-Cardalda, José María Cancela-Carral, María Helena Vila-Suárez
The aim of this study was to assess the effect of a physical exercise program based on Mat Pilates (MP) with TheraBand® on the dynamic balance of a sample population diagnosed with Parkinson's disease (PD). After random selection, 26 participants were allocated to a MP group or a control group where they performed calisthenics exercises. Both interventions lasted 12 weeks and involved 2 weekly sessions of 60 minutes. Assessments took place at baseline, 12 weeks after the intervention started and 4 weeks after the intervention was completed using the body mass index (BMI), the Timed Up and Go (TUG) test with Wiva® sensors, the 30 Second Chair Stand test, and the Five Times Sit to Stand test...
January 24, 2018: Rejuvenation Research
Nina Pilat, Nicolas Granofszky, Thomas Wekerle
Purpose of Review: The mixed chimerism approach is an exceptionally potent strategy for the induction of donor-specific tolerance in organ transplantation and so far the only one that was demonstrated to work in the clinical setting. Regulatory T cells (Tregs) have been shown to improve chimerism induction in experimental animal models. This review summarizes the development of innovative BMT protocols using therapeutic Treg transfer for tolerance induction. Recent Findings: Treg cell therapy promotes BM engraftment in reduced conditioning protocols in both, mice and non-human primates...
2017: Current Transplantation Reports
Seok-Min Yun, Sang-Kyoon Park, Hee Sung Lim
[Purpose] This study was to observe the influence of Pilates training on the quality of life in chronic stoke patients. [Subjects and Methods] Forty chronic stroke patients participated in this study. They were divided into same number of experimental group (EG) and control group (CG). EG participated in a 60-min Pilates training program, twice a week for 12 weeks, while the CG did not participate in any exercise-related activities for the duration and participating in general occupational therapy without any exercise-related activities...
October 2017: Journal of Physical Therapy Science
Ika Oktaviani
OBJECTIVE: This study aims to evaluate the effects of Pilates exercises for a decreasing pain in pregnant women. METHODS: A total of 40 pregnant women were divided into two groups, a control group (followed a standard pregnancy exercise regimen) and a Pilates group (completed a Pilates exercise regimen). A pain assessment was carried out after exercise, using a visual analog scale. The Pilates group workout program lasted 70-80 min per day, once a week, for 8 weeks...
November 16, 2017: Complementary Therapies in Clinical Practice
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