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Fertility preservation

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https://www.readbyqxmd.com/read/28819682/laparoscopy-or-laparotomy-as-the-way-of-entrance-in-myoma-enucleation
#1
REVIEW
Cristina Cezar, Sven Becker, Attilio di Spiezio Sardo, Anja Herrmann, Angelika Larbig, Vasilis Tanos, Luz Angela Torres de la Roche, Hugo Christian Verhoeven, Markus Wallwiener, Rudy Leon De Wilde
PURPOSE: Uterine myomas are the main cause of benign uterine diseases in premenopausal women. Objective of the present paper is to investigate the current best treatment modalities of myomas, depending on age of the patient and her desire to preserve fertility, as well as on clinical presentation of this pathology, such as size, number, and location of fibroids and, furthermore, on surgical experience of the gynecologist. METHODS: The design of our work is a systematic literature review of existing studies, reviews, and meta-analysis conducted in PubMed and Cochrane Library to identify relevant literature...
August 17, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28816706/prognostic-factors-for-recurrence-after-fertility-preserving-surgery-in-patients-with-borderline-ovarian-tumors-a-systematic-review-and-meta-analysis-of-observational-studies
#2
Xiaobing Jiao, Jun Hu, Lirong Zhu
OBJECTIVE: The aim of this study was to find the unfavorable prognostic factors for recurrence after fertility-preserving surgery (FPS) in patients with borderline ovarian tumors (BOTs). METHODS: To perform a meta-analysis to compare the recurrence rates of BOT patients after FPS according to different prognostic factors, we searched PubMed, EMBASE, and Cochrane for observational studies. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated with a fixed-effects model...
August 14, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28815550/fertility-preservation-in-women-with-borderline-ovarian-tumors-how-does-it-impact-disease-outcome-a-cohort-study
#3
Limor Helpman, Assaf Yaniv, Mario E Beiner, Sarit Aviel-Ronen, Tamar Perri, Gilad Ben-Baruch, Liat Hogen Ben-David, Ariella Jakobson-Setton, Jacob Korach
INTRODUCTION: Borderline ovarian tumors are typically indolent neoplasms. Since many are diagnosed in younger women, fertility conservation is an important consideration and has been advocated based on retrospective data. The objective of this study was to identify features impacting on recurrence and survival in a series of borderline ovarian tumors, and to assess the safety of a fertility-sparing approach. MATERIAL AND METHODS: A historical cohort study of consecutive borderline ovarian tumors cases treated at a single institution over 30 years (1981-2011)...
August 16, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28811525/totipotency-segregates-between-the-sister-blastomeres-of-two-cell-stage-mouse-embryos
#4
E Casser, S Israel, A Witten, K Schulte, S Schlatt, V Nordhoff, M Boiani
Following fertilization in mammals, it is generally accepted that totipotent cells are exclusive to the zygote and to each of the two blastomeres originating from the first mitotic division. This model of totipotency was inferred from a minority of cases in which blastomeres produced monozygotic twins in mice. Was this due to experimental limitation or biological constraint? Here we removed experimental obstacles and achieved reliable quantification of the prevalence of dual totipotency among mouse two-cell stage blastomeres...
August 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28809602/fertility-preservation-and-sexual-health-after-cancer-therapy
#5
Nigel Pereira, Glenn L Schattman
Recent developments in cancer diagnostics and treatments have considerably improved long-term survival rates. Despite improvements in chemotherapy regimens, more focused radiotherapy and diverse surgical options, cancer treatments often have gonadotoxic side-effects that can manifest as loss of fertility or sexual dysfunction, particularly in young cancer survivors. In this review, we focus on two pertinent quality-of-life issues in female cancer survivors of reproductive age-fertility preservation and sexual function...
August 15, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28809599/preservation-of-fertility-and-ovarian-function-a-time-sensitive-survivorship-need
#6
Halle C F Moore
No abstract text is available yet for this article.
August 15, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28805599/nationwide-trends-and-in-hospital-complications-of-trachelectomy-for-surgically-resectable-cervical-cancer-in-taiwanese-women-a%C3%A2-population-based-study-1998-2013
#7
Jerry Cheng-Yen Lai, Hung-Hui Chen, Kuei-Hui Chu, Chia-Sui Weng, Yiing-Jenq Chou, Nicole Huang, Yu-Ju Chien, Kung-Liahng Wang
OBJECTIVE: To describe the nationwide trends in the utilization of trachelectomy among Taiwanese women with surgically resectable cervical cancer over the past decade, and to compare associated demographic characteristics, in-hospital complications and related outcomes using a population-based dataset from 1998 to 2013. MATERIALS AND METHODS: We conducted a population-based, cohort study using inpatient admission claims data of Taiwan's National Health Insurance program...
August 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28802955/hysterscopic-resection-of-premalignant-and-malignant-endometrial-polyps-is-it-a-safe-alternative-to-hysterectomy
#8
Osnat Elyashiv, Ron Sagiv, Ram Kerner, Ran Keidar, Joseph Menczer, Tally Levy
STUDY OBJECTIVE: The standard treatment of endometrial cancer (EC) and complex atypical hyperplasia (CAH) is hysterectomy with or without adnexectomy. In the last decade, several centers have attempted to perform hysteroscopic resection of malignant and pre-malignant polyps as an alternative to hysterectomy. In the present study, we evaluated the safety of this procedure in regard to residual uterine pathology. DESIGN: Retrospective chart review DESIGN CLASSIFICATION: Canadian Task Force classification II-2 SETTING: University hospital PATIENTS: 1766 women who underwent hysteroscopic polypectomy during the years 1998-2016 MEASUREMENTS: Patients with CAH and endometrioid type EC in the removed polyps who underwent hysterectomy were included in the study...
August 9, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28801781/acute-pain-crisis-in-a-patient-with-sickle-cell-disease-undergoing-ovarian-simulation-for-fertility-preservation-prior-to-curative-stem-cell-transplantation-case-report-and-literature-review
#9
Michelle Matthews, Rebecca Pollack
PURPOSE: Hematopoietic stem cell transplantation (HSCT) is a cure for sickle cell disease (SCD) but frequently results in permanent sterility. The complications associated with oocyte cryopreservation and risks of future pregnancy are increased in SCD patients. This case report discusses risk reduction strategies and includes a literature review of pregnancy after HSCT. CASE: A 23-year-old woman underwent ovarian stimulation for fertility preservation resulting in cancelation due to acute pain crisis...
August 11, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28800588/non-lethal-genotyping-of-tribolium-castaneum-adults-using-genomic-dna-extracted-from-wing-tissue
#10
Frederic Strobl, J Alexander Ross, Ernst H K Stelzer
The red flour beetle Tribolium castaneum has become the second most important insect model organism and is frequently used in developmental biology, genetics and pest-associated research. Consequently, the methodological arsenal increases continuously, but many routinely applied techniques for Drosophila melanogaster and other insect species are still unavailable. For example, a protocol for non-lethal genotyping has not yet been adapted but is particularly useful when individuals with known genotypes are required for downstream experiments...
2017: PloS One
https://www.readbyqxmd.com/read/28800577/case-report-use-of-tumor-and-germline-y-chromosomal-analysis-to-guide-surgical-management-in-a-46-xx-female-presenting-with-gonadoblastoma-with-dysgerminoma
#11
Jeanna M McCuaig, Abdul Noor, Barry Rosen, Robert F Casper, Frederic Mitri, Terence Colgan, Raymond H Kim
Gonadoblastomas are rare mixed gonadal tumors that are almost always found in individuals with 46, XY karyotype or some other form of Y chromosome mosaicism. It is extremely rare to diagnose gonadoblastoma in phenotypically normal 46, XX females. Herein, we present a 20-year-old 46, XX female diagnosed with gonadoblastoma and dysgerminoma. Use of cytogenetic and molecular analyses to identify the presence of Y chromosome material in peripheral blood, gonadal, and tumor tissue can exclude mosaicism to provide reassurance to undertake conservative surgical management and preserve fertility...
September 2017: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/28797766/pregnancy-outcomes-after-a-breast-cancer-diagnosis-a-systematic-review-and-meta-analysis
#12
REVIEW
Brigitte Gerstl, Elizabeth Sullivan, Angela Ives, Christobel Saunders, Handan Wand, Antoinette Anazodo
Improvements in local and systemic treatment, along with earlier diagnoses through breast awareness and screening, have led to increases in survival and a decline in breast cancer (BC) recurrence. To the best of our knowledge, no meta-analysis has yet focused on pregnancy outcomes after BC treatment. Hence, our research group explored the reproductive outcomes (pregnancy, miscarriage, termination of pregnancy, live births) after BC treatment. The Embase, MEDLINE, PubMed, and Scopus databases were searched. Studies were included that reported on pregnancy and reproductive outcomes after treatment of BC...
July 10, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28796980/ovarian-yolk-sac-tumour-in-a-girl-case-report
#13
Charu Sharma, Hemanshi Shah, Neha Sisodiya Shenoy, Deepa Makhija, Mukta Waghmare
Yolk sac tumours are rare ovarian malignancies accounting for less than 1% of malignant ovarian germ cell tumours. They are mostly seen in adolescents and young women and are usually unilateral making fertility preservation imperative. Raised alpha-feto protein level is the hallmark of this tumour. We describe stage III yolk sac tumour in a girl child.
2017: Developmental Period Medicine
https://www.readbyqxmd.com/read/28796235/development-of-fertile-mouse-oocytes-from-mitotic-germ-cells-in-vitro
#14
Kanako Morohaku, Yuji Hirao, Yayoi Obata
Mammalian fetal ovaries contain numerous primordial germ cells (PGCs), although few mature oocytes are obtained from females, owing to apoptosis and follicle atresia. The regulatory mechanisms underlying oogenesis/folliculogenesis remain unknown. Development of methods for obtaining mature oocytes from PGCs in fetal ovaries in vitro could contribute to clarifying these mechanisms. The failure of follicle assembly has been found to be the most challenging aspect in conventional culture conditions. Recently, we established novel culture conditions that enable successful follicle assembly, sustaining interactions between the oocyte and somatic cells, and, in turn, promoting oocyte growth and maturation...
September 2017: Nature Protocols
https://www.readbyqxmd.com/read/28791295/fertility-preservation-in-endometriosis-patients-anti-m%C3%A3-llerian-hormone-is-a-reliable-marker-of-the-ovarian-follicle-density
#15
Elisabetta Garavaglia, Cinzia Sala, Gianluca Taccagni, Michela Traglia, Caterina Barbieri, Stefano Ferrari, Massimo Candiani, Paola Panina-Bordignon, Daniela Toniolo
OBJECTIVE: To analyze the ovarian reserve via measurement of follicular density and anti-Müllerian hormone (AMH) in endometriosis patients participating to a clinical program of cortical ovarian cryopreservation. DESIGN: Retrospective analysis of serum AMH levels and prospective investigation of ovarian follicle number. SETTING: University Hospital. PATIENTS: Two hundred and two women with endometriosis and 400 controls...
2017: Frontiers in Surgery
https://www.readbyqxmd.com/read/28791274/successful-laparoscopic-management-of-uterine-serosal-pregnancy
#16
Gee Hee Seo, Hyun Jung Lee, Ji-Hyun Jang, Min Chul Choi, Chan Lee, Gwangil Kim
Uterine serosal pregnancy is an extremely rare form of ectopic pregnancy. This is a report of a 35-year-old primigravida woman who was diagnosed with uterine serosal pregnancy via laparoscopic intervention. A 35-year-old woman (gravida 1, para 0) was referred from a local clinic for a ruptured left tubal pregnancy at amenorrhea 5+0 weeks with elevated serum beta human chorionic gonadotropin (16,618 mIU/mL). A pregnancy on the left posterior wall of the uterine serosa was diagnosed during the operation and successfully treated with laparoscopic surgery as a conservative management strategy to enable fertility preservation...
July 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28782618/updates-on-conservative-management-of-endometrial-cancer
#17
REVIEW
Camila Corzo, Natalia Barrientos Santillan, Shannon N Westin, Pedro T Ramirez
Endometrial cancer is the most common gynecologic cancer in the United States. It is typically diagnosed in postmenopausal women. However, given the increasing incidence of risk factors such as obesity and diabetes in younger women, it is becoming a more prevalent problem in this age group. When endometrial cancer is diagnosed in patients of reproductive age, the standard surgical option of hysterectomy and bilateral salpingo-oophorectomy may not be ideal for women interested in future fertility. Hence, conservative options for select patients should be discussed along with the associated outcomes of each approach...
August 3, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28780106/economic-effect-of-reducing-nitrogen-and-phosphorus-mass-balance-on-wisconsin-and-qu%C3%A3-bec-dairy-farms
#18
D Pellerin, E Charbonneau, L Fadul-Pacheco, O Soucy, M A Wattiaux
Our objective was to explore the trade-offs between economic performance (farm net income, FNI) and environmental outcomes (whole-farm P and N balances) of dairy farms in Wisconsin (WI; United States) and Québec (QC; Canada). An Excel-based linear program model (N-CyCLES; nutrient cycling: crops, livestock, environment, and soil) was developed to optimize feeding, cropping, and manure management as a single unit of management. In addition to FNI, P and N balances model outputs included (1) the mix of up to 9 home-grown and 17 purchased feeds for up to 5 animal groups, (2) the mix of up to 5 crop rotations in up to 5 land units and c) the mix of up to 7 fertilizers (solid and liquid manure and 5 commercial fertilizers) to allocate in each land unit...
August 2, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28778097/progress-and-future-prospect-of-in-vitro-spermatogenesis
#19
REVIEW
Fahar Ibtisham, Jiang Wu, Mei Xiao, Lilong An, Zachary Banker, Aamir Nawab, Yi Zhao, Guanghui Li
Infertility has become a major health issue in the world. It affects the social life of couples and of all infertility cases; approximately 40-50% is due to "male factor" infertility. Male infertility could be due to genetic factors, environment or due to gonadotoxic treatment. Developments in reproductive biotechnology have made it possible to rescue fertility and uphold biological fatherhood. In vitro production of haploid male germ cell is a powerful tool, not only for the treatment of infertility including oligozoospermic or azoospermic patient, but also for the fertility preservation in pre-pubertal boys whose gonadal function is threatened by gonadotoxic therapies...
July 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/28770098/boar-management-and-semen-handling-factors-affect-the-quality-of-boar-extended-semen
#20
REVIEW
Alfonso Lopez Rodriguez, Ann Van Soom, Ioannis Arsenakis, Dominiek Maes
Artificial insemination (AI) is the preferred method for reproduction in the majority of the intensive pig production systems Worldwide. To this end, fresh extended ready-to-use semen doses are either purchased from AI-centres or produced by boars kept on-farm. For profitable semen production, it is necessary to obtain a maximum amount of high quality semen from each boar. This paper reviews current knowledge on factors that may affect semen quality by influencing the boar or the semen during processing. Genetic markers could be used for early detection of boars with the highest fertility potential...
2017: Porcine Health Management
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