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Fertility preservation

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https://www.readbyqxmd.com/read/28424089/feasibility-of-uterine-preservation-in-the-management-of-early-stage-uterine-adenosarcomas-a-single-institute-experience
#1
Young-Jae Lee, Dae-Yeon Kim, Dae-Shik Suh, Jong-Hyeok Kim, Yong-Man Kim, Young-Tak Kim, Joo-Hyun Nam
BACKGROUND: We aimed to evaluate the efficacy and the safety of uterine preservation in patients with early-stage uterine adenosarcoma who want to preserve future fertility. METHODS: We performed a retrospective review of patients with stage I uterine adenosarcoma diagnosed and treated at a single institute from 1998 through 2014. RESULTS: Among the total of 31 patients, uterine preservation surgery was performed in 7 of the nulliparas. Of the 7 patients receiving uterine preservation surgery, 3 showed no evidence of disease (NED), 2 had persistent disease confined to the uterus, and 2 were alive with disease (AWD) after recurrence...
April 19, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28423955/double-ovarian-stimulation-duostim-protocol-for-fertility-preservation-in-female-oncology-patients
#2
Nikolaos Tsampras, Della Gould, Cheryl T Fitzgerald
This article describes a revised ovarian stimulation protocol (DuoStim) for fertility preservation in female oncology patients which aims to maximise the number of gametes obtained with subsequent improvement in cumulative birth rate, without delaying cancer treatment. Ten patients diagnosed with malignancy between September 2014 and October 2015 were included. The patients were treated with the DuoStim protocol, undergoing two consecutive ovarian stimulation cycles and two oocyte retrievals. The primary outcome was the number of oocytes collected and vitrified during each oocyte retrieval and in total...
February 9, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28422387/should-we-be-putting-our-scalpel-down-is-hifu-the-answer-to-fertility-sparing-fibroid-treatment
#3
Nicola Tempest, Dharani Hapangama
Despite HIFU being a fertility sparing, outpatient procedure reported to be safe and effective in treating patients with fibroids for 15 years (Wang et al. Zhonghua Chao Sheng Ying Xiang Xue Za Zhi 2002; 11:161-63); approved by the FDA in America in 2004; and seen to have similar cost-effectiveness as all other uterine preserving treatments; it is currently only available in two private treatment centers and on a case by case basis on the NHS in the UK and not consistently covered by any major US insurance company...
April 19, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28421948/talk-about-fertility-even-with-children-says-college
#4
Alistair Kleebauer
The RCN is encouraging nurses to talk about preserving fertility with young people undergoing treatment that could make it difficult for them to conceive.
April 19, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28421500/chapter-16-directional-freezing-of-ovarian-tissue-and-freeze-drying-of-stem-cells-for-fertility-preservation
#5
Amir Arav, Yehudit Natan
Fertility preservation is practiced today for women in their fertile years who wish or need to postpone or prolong their reproductive era. Currently women have two main options to preserve their fertility either by oocyte vitrification or by freezing of ovarian cortical slices. In this chapter we will describe the use of directional freezing for cortical slices and freeze-drying of stem cells. These procedures open the way for the preservation of reproductive cells and tissue for future use in fertility preservation treatments...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28421499/chapter-15-development-of-a-nationwide-network-for-ovarian-tissue-cryopreservation
#6
Jana Liebenthron, Markus Montag
Ovarian tissue cryopreservation is gaining much interest since the publication of the first live birth after retransplantation of frozen-thawed tissue in 2004 (Donnez et al., Lancet 364:1405-1410, 2004). In contrast to cryopreservation of gametes and embryos, ovarian tissue freezing is a complex requiring a proper approach in order to make this a viable option for fertility preservation of cancer patients. Due to the need in terms of laboratory space, equipment, personnel, and adequate logistics, an ovarian tissue cryobank is most economic if managed as a centralized service unit that interacts with numerous clinics covering the surgical part...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28421498/chapter-14-establishing-an-oocyte-cryobank-network
#7
James Graham, Josh Lim, Michael Tucker
Improvements in oocyte cryopreservation has prompted wider acceptance of this technology leading to its use for several reasons. Notably, in addition to elective and medically driven reasons for oocyte cryostorage for fertility preservation, donor oocyte cryobanking is beginning to gain traction, potentially replacing fresh oocyte donation in assisted reproduction. Donor "egg banking," while not totally analogous to donor sperm banking, does provide strong benefits in terms of scheduling flexibility and improved clinical efficiencies, while providing a wider immediate inventory choice...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28421497/chapter-13-human-ovarian-tissue-vitrification
#8
Sherman Silber
Ovarian freezing and transplantation has garnered increasing interest as a potential way of preserving fertility in cancer patients as well as for women who just wish to delay childbearing. This chapter spells out our techniques of ovarian cortex vitrification and results for frozen compared to fresh ovarian cortex transplantation (in one single series from one center for the sake of consistency), as well as potentially provides insight into the mechanism behind ovarian follicle recruitment. This represents an effort to simplify and popularize an approach that has yielded favorable results (all cases recovered ovulation and 75% had successful spontaneous pregnancy) in one single, disciplined study...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28421495/chapter-11-human-embryo-vitrification
#9
Juergen Liebermann
Cryopreservation is one of the keystones in clinical infertility treatment. In particular vitrification has become a well-established and widely used routine procedure that has allowed important expansion of therapeutic strategies when IVF is used to treat infertility. Vitrification of human blastocysts allows us to maximize the potential for conception from any single in vitro fertilization cycle and prevents wastage of embryos. The technology may even be used to eliminate fresh embryo transfers for reasons of convenience, uterine receptivity, fertility preservation, preimplantation genetic diagnosis, or emergency management...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28421489/chapter-5-slow-freezing-of-human-sperm
#10
Ashok Agarwal, Eva Tvrda
Cryopreservation of human spermatozoa is a highly efficient procedure for managing male fertility, and much of its successful application seems to have a crucial impact on the reproductive outcome of assisted reproduction technologies. Here, we present, explain, and describe the slow freezing method for preserving human spermatozoa, which is currently the most commonly used freezing technique in most clinical andrology laboratories.
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28420498/intraoperative-aortic-balloon-occlusion-in-patients-with-placenta-previa-and-or-placenta-accreta-a-retrospective-study
#11
Fangyuan Luo, Lan Xie, Ping Xie, Siwei Liu, Yue Zhu
OBJECTIVE: To introduce the primary experience of using aortic balloon catheters during cesarean section for placenta previa and/or placenta accreta. MATERIALS AND METHODS: From January 2013 to May 2015, 43 patients who were preoperatively diagnosed with major placenta previa and/or placenta accreta and who underwent prophylactic aortic catheterization before caesarean section (CS) were included in the study. We analyzed the clinical data of the study population...
April 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28420497/radical-trachelectomy-for-early-stage-cervical-cancer-a-case-series-and-literature-review
#12
Chin-Jui Wu, Wen-Chun Chang, Chi-Hau Chen, Chi-An Chen, Su-Cheng Huang, Bor-Ching Sheu
OBJECTIVE: Radical trachelectomy (RT) is an alternative treatment for preserving fertility in patients with cervical cancer. Because women with operable cervical cancer opting for fertility preservation are scarce, few cases have been reported in Taiwan. Here we report our cases series. MATERIALS AND METHODS: We retrospectively evaluated seven patients who underwent vaginal RT and three patients who underwent abdominal RT in a single medical institute for a median follow-up period of 5 years...
April 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28418849/oncologic-and-obstetrical-outcomes-with-fertility-sparing-treatment-of-cervical-cancer-a-systematic-review-and-meta-analysis
#13
REVIEW
Qing Zhang, Wenhui Li, Margaux J Kanis, Gonghua Qi, Minghao Li, Xingsheng Yang, Beihua Kong
OBJECTIVE: The objectives of this study were to evaluate the rates of recurrence, survival and pregnancy, and characterize pregnancy outcomes of early-stage cervical cancer(eCC) treated with fertility-sparing methods such as cervical conization (CON) and radical trachelectomy(RT) with or without pelvic lymphadenectomy. STUDY DESIGN: This was a meta-analysis of observational studies analyzed by a random-effects model and a meta-regression to assess heterogeneity...
March 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28415950/ovarian-cystectomy-in-the-treatment-of-apparent-early-stage-immature-teratoma
#14
Ting Zhao, Yan Liu, Xiao Wang, Hao Zhang, Yuan Lu
Objective To investigate the role of ovarian cystectomy in patients with early-stage immature teratoma. Methods A retrospective review was undertaken on patients diagnosed pathologically with immature teratoma and with malignant lesions confined to the ovary. Patients were included if they had been treated between January 1997 and December 2015 at the Obstetrics and Gynaecology Hospital of Fudan University, Shanghai, China. Relevant demographic and clinical data were retrieved from the medical records. Results Forty-three patients were included in the study; 14 underwent ovarian cystectomy (group 1) and 29 underwent unilateral salpingo-oophorectomy (USO; group 2)...
April 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28412286/beneficial-effects-of-glutathione-supplementation-during-vitrification-of-mouse-oocytes-at-the-germinal-vesicle-stage-on-their-preimplantation-development-following-maturation-and-fertilization-in-vitro
#15
Adel R Moawad, Seang Lin Tan, Teruko Taketo
Oocyte cryopreservation is imperative for assisted reproductive technologies (ART). Although cryopreservation of oocytes at the Metaphase II has been widely used, immature oocytes at the germinal vesicle stage (GV-oocytes) need to be cryopreserved in certain situations such as cancer patients; however, the success rate of embryonic development from the GV-oocytes remains low largely due to the requirement for in vitro maturation (IVM). Our aim was to investigate the effects of glutathione (GSH) supplementation during vitrification and warming of mouse GV-oocytes on the preservation of developmental competence...
April 12, 2017: Cryobiology
https://www.readbyqxmd.com/read/28403592/comparison-of-transurethral-incision-of-the-prostate-and-silodosin-in-patients-having-benign-prostatic-obstruction-in-terms-of-retrograde-ejaculation
#16
Basri Cakiroglu, Aydin Ismet Hazar, Orhun Sinanoglu, Ersan Arda, Sinan Ekici
BACKGROUND: To compare the functional outcomes and retrograde ejaculation (RE) after transurethral incision of the prostate (TUIP) or silodosin in bladder outlet obstruction (BOO) secondary to a small prostate. METHODS: Prospectively collected data from December 2011 through December 2014 of 192 LUTS patients having fertility concerns with prostate volume smaller than 40 ml receiving either TUIP or silodosin treatment were prospectively reviewed. The treatment outcomes were evaluated and compared...
March 31, 2017: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28402059/molecular-markers-of-putative-spermatogonial-stem-cells-in-the-domestic-cat
#17
S J Bedford-Guaus, S Kim, L Mulero, J M Vaquero, C Morera, R Adan-Milanès, A Veiga, Á Raya
Spermatogonial stem cells (SSCs) are an important tool for fertility preservation and species conservation. The ability to expand SSCs by in vitro culture is a crucial premise for their use in assisted reproduction. Because SSCs represent a small proportion of the germ cells in the adult testis, culture success is aided by pre-enrichment through sorting techniques based on cell surface-specific markers. Given the importance of the domestic cat as a model for conservation of endangered wild felids, herein we sought to examine culture conditions as well as molecular markers for cat SSCs...
April 2017: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/28398834/dry-preservation-of-spermatozoa-considerations-for-different-species
#18
Jennifer Patrick, Pierre Comizzoli, Gloria Elliott
The current gold standard for sperm preservation is storage at cryogenic temperatures. Dry preservation is an attractive alternative, eliminating the need for ultralow temperatures, reducing storage maintenance costs, and providing logistical flexibility for shipping. Many seeds and anhydrobiotic organisms are able to survive extended periods in a dry state through the accumulation of intracellular sugars and other osmolytes and are capable of returning to normal physiology postrehydration. Using techniques inspired by nature's adaptations, attempts have been made to dehydrate and dry preserve spermatozoa from a variety of species...
April 2017: Biopreservation and Biobanking
https://www.readbyqxmd.com/read/28398024/gonadotropin-releasing-hormone-analogues-for-the-prevention-of-chemotherapy-induced-premature-ovarian-failure-in-breast-cancer-patients
#19
Benedetta Conte, Lucia Del Mastro
Since the survival of patients with cancer has significantly improved, chemotherapy-related premature ovarian failure (POF) in young cancer survivors has become a major issue in oncology. POF is associated with several health-related negative consequences, including menopausal symptoms, increased risk of cardiovascular diseases, osteoporosis, sexual disfunction, and infertility1-5. According to the major international guidelines, embryo/oocyte cryopreservation are the standard procedures for fertility preservation in young cancer women6,7...
April 10, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28395972/optimization-of-conditions-for-the-cryopreservation-of-yellow-catfish-pelteobagrus-fulvidraco-sperm
#20
Sen Yang, Linqiang Han, Rushou Huang, Yongzhong Liufu, Zining Meng, Haoran Lin
Yellow catfish (Pelteobagrus fulvidraco) is a promising aquaculture species in China with an increasing market demand. To serve the growing demand of male broodstock for artificial fertilization and the preservation of valuable strains for selective breeding, we tried to develop a species-specific cryopreservation protocol for yellow catfish sperm in this study. Important factors such as cryoprotectant, freezing height above the liquid nitrogen (LN) surface, dilution ratio, equilibration time, thawing temperature and cool storage before freezing were standardized...
April 7, 2017: Cryobiology
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