osteomyelitits

A 63-year-old woman with NIDDM poorly controlled by insulin therapy was admitted to our hospital because of fever and severe lumbago. Laboratory data revealed diabetic ketosis and a hypercoagulable state with infection. Bone and gallium scintigrams revealed an abnormal accumulation of the isotopes at L4-L5, where magnetic resonance imaging showed inflammatory changes. The patient was then diagnosed as having pyogenic vertebral osteomyelitis. Antibiotic chemotherapy and the administration of gebexate mesilate improved the inflammation and hypercoagulable state...

The fact that the hematogenic osteomyelitis can be cured, if a treatment with antibiotics is done early, confines the very difficult question about the correlation between trauma and hematogenous osteomyelitis to exceptional cases. Under certain conditions which have to be described in a more precise way, the trauma sometimes takes the form of an activating partial factor among the variety of causes of the hematogenous osteomyelitis, but is never the only producing cause. Fistulous chronic osteomyelitites are subject to a malignant degeneration at a specified frequency of up to 0...