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https://www.readbyqxmd.com/read/29216020/hydrolyzed-formula-with-reduced-protein-content-supports-adequate-growth-a-randomized-controlled-non-inferiority-trial
#1
Birgit Ahrens, Christian Hellmuth, Nadja Haiden, Dirk Olbertz, Eckard Hamelmann, Milica Vusurovic, Manja Fleddermann, Robert Roehle, Anette Knoll, Berthold Koletzko, Ulrich Wahn, Kirsten Beyer
OBJECTIVE: A high protein content of non-hydrolyzed infant formula exceeding metabolic requirements can induce rapid weight gain and obesity. Hydrolyzed formula with too low protein (LP) content may result in inadequate growth. The aim of this study was to investigate non-inferiority of partial and extensively hydrolyzed formulas (pHF, eHF) with lower hydrolyzed protein content than conventionally, regularly used formulas, with or without synbiotics for normal growth of healthy term infants...
December 5, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29205932/designing-synbiotics-for-improved-human-health
#2
EDITORIAL
Sean M Kearney, Sean M Gibbons
No abstract text is available yet for this article.
December 4, 2017: Microbial Biotechnology
https://www.readbyqxmd.com/read/29204050/current-and-emerging-pharmacological-therapy-for-non-alcoholic-fatty-liver-disease
#3
EDITORIAL
Ahad Eshraghian
The main treatment of patients with non-alcoholic fatty liver disease (NAFLD) is life style modification including weight reduction and dietary regimen. Majority of patients are safely treated with this management and pharmacologic interventions are not recommended. However, a subgroup of NAFLD patients with non-alcoholic steatohepatitis (NASH) who cannot achieve goals of life style modification may need pharmacological therapy. One major obstacle is measurement of histological outcome by liver biopsy which is an invasive method and is not recommended routinely in these patients...
November 14, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29202875/postoperative-changes-of-the-microbiome-are-surgical-complications-related-to-the-gut-flora-a-systematic-review
#4
Ann-Kathrin Lederer, Przemyslaw Pisarski, Lampros Kousoulas, Stefan Fichtner-Feigl, Carolin Hess, Roman Huber
BACKGROUND: The purpose of this review was to identify the relationship between the gut microbiome and the development of postoperative complications like anastomotic leakage or a wound infection. Recent reviews focusing on underlying molecular biology suggested that postoperative complications might be influenced by the patients' gut flora. Therefore, a review focusing on the available clinical data is needed. METHODS: In January 2017 a systematic search was carried out in Medline and WebOfScience to identify all clinical studies, which investigated postoperative complications after gastrointestinal surgery in relation to the microbiome of the gut...
December 4, 2017: BMC Surgery
https://www.readbyqxmd.com/read/29201766/are-synbiotics-added-to-the-standard-therapy-to-eradicate-helicobacter-pylori-in-children-beneficial-a-randomized-controlled-study
#5
Banu N Şirvan, Merve K Usta, Nurav U Kizilkan, Nafive Urganci
Aim: We aimed to evaluate the role of the addition of Bifidobacterium /actis-containing synbiotic to the triple therapy in the case of He/icobacter py/ori eradication, the dyspeptic symptoms, and reducing the side effects of antibiotics. Materials and methods: A total of 104 children aged between 5 and 17 years, who were histopathologically diagnosed with H. py/ori were enrolled in this study, of whom 100 were included in the analysis. Patients were randomly classified into two groups...
January 2017: Euroasian Journal of Hepato-Gastroenterology
https://www.readbyqxmd.com/read/29196919/the-combined-efficiency-of-dietary-isomaltooligosaccharides-and-bacillus-spp-on-the-growth-hemato-serological-and-intestinal-microbiota-indices-of-caspian-brown-trout-salmo-trutta-caspius-kessler-1877
#6
Maryam Aftabgard, Alireza Salarzadeh, Mahmoud Mohseni, Amir Houshang Bahri Shabanipour, Mohammad Ebrahim Jalil Zorriehzahra
The combined effects of a commercial probiotic, BetaPlus®, and a prebiotic, isomaltooligosaccharides (IMOS) on the growth, survival rate, intestinal microbiota, and hemato-immunological parameters were evaluated in Caspian brown trout (Salmo trutta caspius Kessler, 1877). Caspian brown trout fingerlings (~ 9 g) were fed a control diet (basal diet) or a synbiotic diet (the basal diet + 2 g kg-1 IMOS + 1 g kg-1 BetaPlus®) for 7 weeks. At the end of this trial, fish fed the synbiotic diet showed significant improvements in body weight increase, feed conversion ratio, and survival rate compared with fish fed the control diet (P < 0...
December 1, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29186118/corrigendum-a-randomized-synbiotic-trial-to-prevent-sepsis-among-infants-in-rural-india
#7
Pinaki Panigrahi, Sailajanandan Parida, Nimai C Nanda, Radhanath Satpathy, Lingaraj Pradhan, Dinesh S Chandel, Lorena Baccaglini, Arjit Mohapatra, Subhranshu S Mohapatra, Pravas R Misra, Rama Chaudhry, Hegang H Chen, Judith A Johnson, J Glenn Morris, Nigel Paneth, Ira H Gewolb
This corrects the article DOI: 10.1038/nature23480.
November 29, 2017: Nature
https://www.readbyqxmd.com/read/29185825/effect-of-probiotic-supplementation-on-cd4-cell-count-in-hiv-infected-patients-a-systematic-review-and-meta-analysis
#8
Asma Kazemi, Kurosh Djafarian, John R Speakman, Parviz Sabour, Sepideh Soltani, Sakineh Shab-Bidar
Progressive decline in CD4 cell counts is associated with human immunodeficiency virus (HIV) disease progression. Loss of CD4 cells might contribute to gut microbiota alteration and bacterial translocation. Probiotics, by inducing epithelial healing, may promote the restoration of the intestinal CD4+ T-cell population. The aim of this meta-analysis was to systematically review all randomized controlled trials (RCTs) of probiotic/prebiotic/synbiotic supplementation on CD4 cell counts in HIV-infected patients...
November 29, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/29181802/study-and-understanding-behavior-of-alginate-inulin-synbiotics-beads-for-protection-and-delivery-of-antimicrobial-producing-probiotics-in-colonic-simulated-conditions
#9
Abdelbasset Atia, Ahmed Gomaa, Benoit Fernandez, Muriel Subirade, Ismail Fliss
According to the World Health Organization (WHO), using antibiotics as growth promoters for livestock-particularly swine-is the principal cause of antibiotic resistance. It is therefore clear that finding an alternative to antibiotics becomes an emergency. Hundreds of recent studies have appointed probiotics as potential candidates to replace or to be used in combination with antibiotics. However, bringing probiotics alive to the colon-their site of action-remains a big challenge because of different physiological barriers encountered in proximal gastrointestinal tract (GIT) such as acidic pH and bile salts that may affect the viability of probiotic cultures...
November 27, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29155807/a-synbiotic-containing-amino-acid-based-formula-improves-gut-microbiota-in-non-ige-mediated-allergic-infants
#10
David C A Candy, Marleen T J Van Ampting, Manon M Oude Nijhuis, Harm Wopereis, Assad M Butt, Diego G Peroni, Yvan Vandenplas, Adam T Fox, Neil Shah, Christina E West, Johan Garssen, Lucien F Harthoorn, Jan Knol, Louise J Michaelis
BACKGROUND: Prebiotics and probiotics (synbiotics) can modify gut microbiota and have potential in allergy management when combined with amino acid-based formula (AAF) for infants with cow's milk allergy (CMA). METHODS: This multicenter, double-blind, randomized controlled trial investigated the effects of an AAF including synbiotic blend on percentages of bifidobacteria and Eubacterium rectale/Clostridium coccoides group (ER/CC) in feces from infants with suspected non-IgE-mediated CMA...
November 20, 2017: Pediatric Research
https://www.readbyqxmd.com/read/29151980/synbiotic-effects-of-%C3%AE-glucans-from-cauliflower-mushroom-and-lactobacillus-fermentum-on-metabolic-changes-and-gut-microbiome-in-estrogen-deficient-rats
#11
Seong-Yeop Jeong, Suna Kang, Cao Shi Hua, Zhang Ting, Sunmin Park
Background: We investigated whether the long-term consumption of a symbiotic formulation with Lactobacillus fermentum (probiotic) and β-glucan from cauliflower mushroom (prebiotic) would delay the progression of post-menopausal symptoms in ovariectomized (OVX) rats and explored their mechanisms of action, including changes in gut microbiota. Methods: OVX rats were fed with high-fat diets containing 1% dextrin (control), 1% lyophilized cauliflower mushroom extract (CFM), 0...
2017: Genes & Nutrition
https://www.readbyqxmd.com/read/29143664/evaluation-of-dirofilaria-immitis-antigen-detection-comparing-heated-and-unheated-serum-in-dogs-with-experimental-heartworm-infections
#12
James Carmichael, Scott McCall, Utami DiCosty, Abdelmoneim Mansour, Linda Roycroft
BACKGROUND: To evaluate whether heated serum allows for earlier detection of Dirofilaria immitis antigen, dogs with experimental D. immitis infections underwent weekly blood sampling to compare antigen results using both heated and unheated serum. METHODS: One of two isolates (JYD-34 or Big Head™) were used to infect naïve laboratory beagle dogs. Serum was collected from dogs weekly and divided into two aliquots, heated and unheated. The samples designated as heated were placed in a heat block at 104 °C for 10 min then centrifuged with collection of the resulting supernatant...
November 9, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29136611/gut-microbiota-in-health-and-disease
#13
Yuichiro Yamashiro
Intestinal regulatory T (Treg) cells are critical to maintaining immune tolerance to dietary antigens and gut microbiota. This paper reviews several papers on this topic that were recently published by Japanese researchers. Specifically, Prof. K. Honda and his group have found that commensal microbiota capable of metabolizing butyrate induces the differentiation of colonic Treg cells. In a separate work, Prof. Y. Yokoyama and his group used a novel, culture-independent analytical method (the Yakult Intestinal Flora-Scan) for detection of bacteria in the bloodstream...
November 14, 2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/29134293/medicinal-foods-for-functional-gi-disorders
#14
REVIEW
Brent W Acker, Brooks D Cash
PURPOSE OF REVIEW: Over the past 10 years, there has been a dramatic increase in basic and clinical research involving functional gastrointestinal disorders (FGIDs). New diagnostic and biomarker procedures are helping to identify physiologic disruptions associated with FGIDs on cellular and molecular levels. Simultaneously, clinicians are using new approaches to help manage patients with FGIDs. Among these, an important component of care has been the use of medical foods. These include probiotics, prebiotics, synbiotics, peppermint oil, caraway oil, curcumin, bovine immunoglobulin and many others...
November 13, 2017: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/29130749/does-maternal-synbiotic-supplementation-affect-conjugated-linoleic-acid-level-in-breast-milk-a-randomized-placebo-controlled-clinical-trial
#15
Leila Nikniaz, Reza Mahdavi, Alireza Ostadrahimi, Zeinab Nikniaz, Soghra Aliasgharzadeh
AIM: As conjugated linoleic acid (CLA)is a potential growth promotor in newborns, the present pilot study aimed at measuring the effect of synbiotic supplementation on breast milk CLA level. MATERIALS AND METHODS: Sixty lactating mothers were randomly allocated to take either synbiotic (n = 31) or placebo (n = 29) for 30 days. Maternal anthropometric indices were measured at the onset and end of the study by standard methods and body mass index was calculated...
November 13, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/29122477/development-and-characterization-of-an-innovative-synbiotic-fermented-beverage-based-on-vegetable-soybean
#16
Carolina Battistini, Beatriz Gullón, Erica Sayuri Ichimura, Ana Maria Pereira Gomes, Eliana Paula Ribeiro, Leo Kunigk, José Ubirajara Vieira Moreira, Cynthia Jurkiewicz
Soymilk was produced from vegetable soybean and fermented by probiotics (Lactobacillus acidophilus La-5, Bifidobacterium animalis Bb-12) in co-culture with Streptococcus thermophilus. The composition of the fermented beverage and oligosaccharides content were determined. The effect of fructooligosaccharides and inulin on the fermentation time and viability of probiotic microorganisms throughout 28 days of storage at 5°C were evaluated. The soymilk from vegetable soybeans was fermented in just 3.2h, when pH reached 4...
October 18, 2017: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/29119465/probiotic-and-synbiotic-sorbets-produced-with-jussara-euterpe-edulis-pulp-evaluation-throughout-the-storage-period-and-effect-of-the-matrix-on-probiotics-exposed-to-simulated-gastrointestinal-fluids
#17
Júlia Fernanda Urbano Marinho, Marluci Palazzolli da Silva, Marcella Chalella Mazzocato, Fabrício Luiz Tulini, Carmen Sílvia Favaro-Trindade
The aims of the present study were to develop and evaluate different formulations of probiotic and synbiotic sorbets produced with jussara (Euterpe edulis) pulp, polydextrose, Lactobacillus acidophilus LA3, and Lactobacillus paracasei BGP1. The pasteurized jussara pulp presented high content of phenolic compounds, especially anthocyanins, which were not inhibitory to the probiotics used in this study. The levels of polyphenols and anthocyanins present in the sorbets were also high and kept stable for 120 days, as well as the populations of both probiotics...
November 8, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29119235/effect-of-probiotics-and-synbiotics-consumption-on-serum-concentrations-of-liver-function-test-enzymes-a-systematic-review-and-meta-analysis
#18
REVIEW
Saman Khalesi, David Wayne Johnson, Katrin Campbell, Susan Williams, Andrew Fenning, Sonia Saluja, Christopher Irwin
PURPOSE: The gut-liver interaction suggests that modification of gut bacterial flora using probiotics and synbiotics may improve liver function. This systematic review and meta-analysis aimed to clarify the effect of probiotics and synbiotics consumption on the serum concentration of liver function enzymes. METHODS: PubMed (MEDLINE), Cumulative Index to Nursing and Allied Health Literature, and Cochrane Library (Central) were searched from 1980 to August 2017 for studies where adults consumed probiotics and/or synbiotics in controlled trials and changes in liver function enzymes were examined...
November 8, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/29089934/prebiotic-and-synbiotic-modifications-of-beta-oxidation-and-lipogenic-gene-expression-after-experimental-hypercholesterolemia-in-rat-liver
#19
Claudia C Alves, Dan L Waitzberg, Laila S de Andrade, Laís Dos Santos Aguiar, Milene B Reis, Camila C Guanabara, Odair A Júnior, Daniel A Ribeiro, Priscila Sala
Background and aims: Non-alcoholic fatty liver disease (NAFLD) is characterized by the presence of fat in hepatocytes because of decreased β-oxidation and increased lipogenesis. Prebiotics, probiotics, and synbiotic have modulatory effects on intestinal microbiota and may influence the gut-liver axis. Our aim was to evaluate the effects of prebiotic, probiotics, and synbiotic on liver histopathology and gene expression related to β-oxidation and lipogenesis after hypercholesterolemia. Methods: Wistar male adult rats (n = 40) were submitted to hypercholesterolemic conditions (HPC) (60 days)...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29079990/the-effects-of-synbiotic-supplementation-on-carotid-intima-media-thickness-biomarkers-of-inflammation-and-oxidative-stress-in-people-with-overweight-diabetes-and-coronary-heart-disease-a-randomized-double-blind-placebo-controlled-trial
#20
Alireza Farrokhian, Fariba Raygan, Ali Soltani, Maryam Tajabadi-Ebrahimi, Mehran Sharifi Esfahani, Ali Akbar Karami, Zatollah Asemi
Synbiotics are known to exert multiple beneficial effects, including anti-inflammatory and antioxidant actions. The aim of this study was to evaluate the effects of synbiotic supplementation on carotid intima-media thickness (CIMT), biomarkers of inflammation, and oxidative stress in people with overweight, diabetes, and coronary heart disease (CHD). This randomized, double-blind, placebo-controlled trial was conducted and involved 60 people with overweight, diabetes, and CHD, aged 50-85 years old. Participants were randomly allocated into two groups to take either synbiotic supplements containing three probiotic bacteria spices Lactobacillus acidophilus strain T16 (IBRC-M10785), Lactobacillus casei strain T2 (IBRC-M10783), and Bifidobacterium bifidum strain T1 (IBRC-M10771) (2 × 10(9) CFU/g each) plus 800 mg inulin or placebo (n = 30 each group) for 12 weeks...
October 27, 2017: Probiotics and Antimicrobial Proteins
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