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Synbiotic

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https://www.readbyqxmd.com/read/28814309/performance-biochemical-and-haematological-responses-and-relative-organ-weights-of-laying-hens-fed-diets-supplemented-with-prebiotic-probiotic-and-synbiotic
#1
Shirley Gee Hoon Tang, Chin Chin Sieo, Kalavathy Ramasamy, Wan Zuhainis Saad, Hee Kum Wong, Yin Wan Ho
BACKGROUND: The increasing trend of ban on the use of antibiotic growth promoters (AGPs) across the globe in the poultry industry has led to a growing need for alternatives to AGPs. Prebiotic, probiotic and their combination as a synbiotic have been considered as potential alternatives. This study aimed to investigate the effects of a prebiotic (isomaltooligosaccharide, IMO), a probiotic (PrimaLac®), and their combination (synbiotic) on hen performance, biochemical and haematological responses, and relative organ weights from 20 to 52 weeks of age...
August 17, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28813414/a-randomized-synbiotic-trial-to-prevent-sepsis-among-infants-in-rural-india
#2
Pinaki Panigrahi, Sailajanandan Parida, Nimai C Nanda, Radhanath Satpathy, Lingaraj Pradhan, Dinesh S Chandel, Lorena Baccaglini, Arjit Mohapatra, Subhranshu S Mohapatra, Pravas R Misra, Rama Chaudhry, Hegang H Chen, Judith A Johnson, J Glenn Morris, Nigel Paneth, Ira H Gewolb
Sepsis in early infancy results in one million annual deaths worldwide, most of them in developing countries. No efficient means of prevention is currently available. Here we report on a randomized, double-blind, placebo-controlled trial of an oral synbiotic preparation (Lactobacillus plantarum plus fructooligosaccharide) in rural Indian newborns. We enrolled 4,556 infants that were at least 2,000 g at birth, at least 35 weeks of gestation, and with no signs of sepsis or other morbidity, and monitored them for 60 days...
August 16, 2017: Nature
https://www.readbyqxmd.com/read/28797988/effects-of-long-term-synbiotic-supplementation-in-addition-to-lifestyle-changes-in-children-with-obesity-related-non-alcoholic-fatty-liver-disease
#3
Murat Çakır, Ayşe Aksel İşbilen, İlker Eyüpoğlu, Elif Sağ, Asım Örem, Tuğba Mazlum Şen, Neşe Kaklıkkaya, Gülay Kaya
BACKGROUND/AIMS: We aimed to analyze the efficiency of a novel treatment approach, long-term synbiotic supplementation, in addition to lifestyle changes in children with non-alcoholic fatty liver disease (NAFLD). MATERIALS AND METHODS: The study included children with NAFLD (n=28) and a healthy control group (n=30). Children with NAFLD were given 1 capsule/day of synbiotics. Anthropometric parameters; biochemical analysis, including ethanol, tumor necrosis factor-α (TNF-α), total oxidant status (TOS) and anti-oxidant status (TAS), zonulin, and fecal calprotectin; and ultrasonographic examination were performed at baseline and 4 months later...
August 9, 2017: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/28793992/short-chain-fatty-acids-prebiotics-synbiotics-and-systemic-inflammation-a-systematic-review-and-meta-analysis
#4
Rebecca F McLoughlin, Bronwyn S Berthon, Megan E Jensen, Katherine J Baines, Lisa G Wood
Background: Prebiotic soluble fibers are fermented by beneficial bacteria in the colon to produce short-chain fatty acids (SCFAs), which are proposed to have systemic anti-inflammatory effects.Objective: This review examines the effect of SCFAs, prebiotics, and pre- and probiotic combinations (synbiotics) on systemic inflammation.Design: Relevant English language studies from 1947 to May 2017 were identified with the use of online databases. Studies were considered eligible if they examined the effects of SCFAs, prebiotics, or synbiotics; were delivered orally, intravenously, or per rectum; were on biomarkers of systemic inflammation in humans; and performed meta-analysis where possible...
August 9, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28781771/the-impact-of-synbiotic-administration-through-in-ovo-technology-on-the-microstructure-of-a-broiler-chicken-small-intestine-tissue-on-the-1-st-and-42-nd-day-of-rearing
#5
A Sobolewska, J Bogucka, A Dankowiakowska, G Elminowska-Wenda, K Stadnicka, M Bednarczyk
BACKGROUND: Application the innovative method which is in ovo technology provides a means of modulating the immune system at early embryonic stages. The aim of study was to determine influence of the in ovo stimulation, on d 12 of incubation, with synbiotics (synbiotic 1- L. salivarius IBB3154 + Bi(2)tos, Clasado Ltd. and the synbiotic 2 - L. plantarum IBB3036 + lupin RFOs) on the microstructure of duodenum, jejunum and ileum in the 1(st) and 42(nd) day of rearing. RESULTS: On the 1(st) day of chickens life, in the duodenum of both experimental groups (SYN1 and SYN2), a significantly higher and wider intestinal villi as well as a significantly larger absorbent surface of these villi were found in comparison with the Control group (P ≤ 0...
2017: Journal of Animal Science and Biotechnology
https://www.readbyqxmd.com/read/28780103/human-milk-oligosaccharide-consumption-by-probiotic-and-human-associated-bifidobacteria-and-lactobacilli
#6
Taksawan Thongaram, Jennifer L Hoeflinger, JoMay Chow, Michael J Miller
Human milk contains high concentrations of nondigestible complex oligosaccharides (human milk oligosaccharides; HMO) that reach the colon and are subsequently fermented by the infant gut microbiota. Using a high-throughput, low-volume growth determination, we evaluated the ability of 12 lactobacilli and 12 bifidobacteria strains, including several commercial probiotics, to ferment HMO and their constituent monomers. Of the 24 strains tested, only Bifidobacterium longum ssp. infantis ATCC 15697 and Bifidobacterium infantis M-63 were able to ferment 3'-sialyllactose, 6'-sialyllactose, 2'-fucosyllactose, and 3'-fucosyllactose...
August 2, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28771949/synbiotic-approaches-to-human-health-and-well-being
#7
Thomas Gurry
Synbiotics refer to combinations of probiotics and prebiotics that act synergistically to confer health benefits to the host. As a therapeutic strategy, they provide a gentle yet powerful method for modulating the composition and metabolic output of the human gut microbiota. In the context of achieving the UN Sustainable Development Goals, synbiotics have the potential to act as cost-effective prophylactic measures against a variety of human ailments, ranging from infant diarrhoea to metabolic and inflammatory diseases in adults, by maintaining commensal microbial communities and metabolic networks that are conducive to human health...
August 3, 2017: Microbial Biotechnology
https://www.readbyqxmd.com/read/28755457/randomized-controlled-crossover-trial-of-prevention-of-clindamycin-induced-gastrointestinal-signs-using-a-synbiotic-in-healthy-research-cats
#8
J E Stokes, J M Price, J C Whittemore
BACKGROUND: Synbiotics often are prescribed to limit antibiotic-associated gastrointestinal signs (AAGS) in cats, but data to support this recommendation are lacking. OBJECTIVE: To determine whether synbiotic co-administration mitigates AAGS in healthy research cats treated with clindamycin. ANIMALS: 16 healthy research cats. METHODS: A randomized, double-blinded, placebo-controlled, 2-way, 2-period, crossover study with a 6-week washout was performed...
July 29, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28730134/innovative-dietary-intervention-answers-to-baby-colic
#9
Ioannis Xinias, A Analitis, Antigoni Mavroudi, Ioannis Roilides, Maria Lykogeorgou, Varvara Delivoria, Vasilis Milingos, Mayra Mylonopoulou, Yvan Vandenplas
PURPOSE: The purpose of this paper is to evaluate the efficacy of a lactose- reduced synbiotic partial whey hydrolysate in formula fed infants presenting with colic and the impact of this dietary intervention in mean crying time and quality of life. METHODS: Forty infants with infantile colic were treated during one month with parental reassurance and the intervention formula (partial whey hydrolysate, reduced lactose, Bifidobacterium lactis BB12 and galacto-oligosaccharides) and were compared to a control group of 20 infants with infantile colic treated with parental reassurance and a standard infant formula...
June 2017: Pediatric Gastroenterology, Hepatology & Nutrition
https://www.readbyqxmd.com/read/28720399/prenatal-and-postnatal-administration-of-prebiotics-and-probiotics
#10
REVIEW
Kristin Sohn, Mark A Underwood
Colonization of the neonatal gut by beneficial bacteria is important for the establishment and maintenance of the mucosal barrier, thus protecting the neonate from enteric pathogens and local and systemic inflammation. The neonatal microbiome is influenced by infant diet, environment, and the maternal microbiome. Dysbiosis in pregnancy increases the risk of pre-eclampsia, diabetes, infection, preterm labor, and later childhood atopy. Dysbiosis of the neonatal gut plays an important role in colic in the term infant, in the disease processes which plague preterm infants, including necrotizing enterocolitis and sepsis, and in the long-term outcomes of neonates...
July 15, 2017: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28714911/nutrition-and-allergic-diseases
#11
EDITORIAL
R J J van Neerven, Huub Savelkoul
The development of IgE-mediated allergic diseases is influenced by many factors, including genetic and environmental factors such as pollution and farming, but also by nutrition. In the last decade, substantial progress has been made in our understanding of the impact that nutrition can have on allergic diseases. Many studies have addressed the effect of breastfeeding, pre-, pro- and synbiotics, vitamins and minerals, fiber, fruit and vegetables, cow's milk, and n-3 fatty acids, on the development of allergies...
July 17, 2017: Nutrients
https://www.readbyqxmd.com/read/28709723/synbiotic-dietary-supplement-affects-growth-immune-responses-and-intestinal-microbiota-of-apostichopus-japonicus
#12
Xitao Wang, Yongxin Sun, Lili Wang, Xiaoyu Li, Kunli Qu, Yongping Xu
A feeding experiment was conducted to investigate the effects of dietary administration of synbiotic with Bacillus lincheniformis WS-2 (CGMCC No. 12813) and alginate oligosaccharides (AOS) on the growth, innate immune response, and intestinal microbiota of the sea cucumber Apostichopus japonicus and its resistance to Vibrio infection. Sea cucumbers were given a control diet (non-supplemented), pro diet (basal diet plus 1 × 10(9) cfu (g diet)(-1)B. lincheniformis WS-2), syn diet (basal diet plus 1 × 10(9) cfu (g diet)(-1)B...
July 11, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28705786/investigation-of-the-efficacy-of-synbiotics-in-the-treatment-of-functional-constipation-in-children-a-randomized-double-blind-placebo-controlled-study
#13
Ahmet Baştürk, Reha Artan, Atike Atalay, Aygen Yılmaz
BACKGROUND/AIMS: The aim of this study was to demonstrate the efficacy of synbiotic (Lactobacillus casei, L. rhamnosus, L. plantarum, and Bifidobacterium lactis and prebiotics [fiber, polydextrose, fructo-oligosaccharides, and galacto-oligosaccharides]) treatment in children with functional constipation. MATERIALS AND METHODS: This study was performed in patients aged 4-18 years, and the patients were diagnosed to have functional constipation according to the Roma III diagnostic criteria...
July 13, 2017: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/28694176/anxiogenic-effects-of-a-lactobacillus-inulin-and-the-synbiotic-on-healthy-juvenile-rats
#14
Camila Barrera-Bugueño, Ornella Realini, Jorge Escobar-Luna, Ramón Sotomayor-Zárate, Martin Gotteland, Marcela Julio-Pieper, Javier A Bravo
Gut microbiota interventions, including probiotic and prebiotic use can alter behavior in adult animals and healthy volunteers. However, little is known about their effects in younger individuals. To investigate this, male Sprague-Dawley rats (post-natal day 21, PND21) received Lactobacillus casei 54-2-33 (10(4)cfu/ml), inulin as prebiotic (16mg/ml), or both together (synbiotic) via drinking water for 14days. Control rats received water alone. Open field (OF) and elevated plus maze (EPM) behaviors were evaluated at PND34 and 35, respectively...
July 8, 2017: Neuroscience
https://www.readbyqxmd.com/read/28681230/probiotics-prebiotics-and-synbiotics-for-the-treatment-and-prevention-of-adult-dermatological-diseases
#15
REVIEW
Manisha Notay, Negar Foolad, Alexandra R Vaughn, Raja K Sivamani
BACKGROUND: Probiotic, prebiotic, and synbiotic supplementation is becoming more prevalent nowadays. Clinical studies have demonstrated some of the medical benefits of probiotics, prebiotics, and synbiotics within dermatology but an evidence-based review of their effects in adults is needed. OBJECTIVE: The aim of this study was to identify evidence for the use of supplementation with probiotics, prebiotics, or synbiotics for the prevention and treatment of dermatological diseases in adults...
July 5, 2017: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/28677046/the-effects-of-synbiotic-supplementation-on-glucose-metabolism-and-lipid-profiles-in-patients-with-diabetes-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#16
REVIEW
Reza Tabrizi, Mahmood Moosazadeh, Kamran B Lankarani, Maryam Akbari, Seyed Taghi Heydari, Fariba Kolahdooz, Zatollah Asemi
Although several studies have evaluated the effect of synbiotic intake on metabolic profiles in patients with diabetes, findings are inconsistent. This systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted to summarize the evidence on the effect of synbiotic intake on metabolic profiles in patients with diabetes. The PubMed, EMBASE, Web of Science, and Cochrane Library databases were systematically searched. All RCTs published up to 12 November 2016 were included. Two review authors independently assessed study eligibility, extracted data, and evaluated risk of bias of included studies...
July 4, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/28659890/pre-cultivation-with-selected-prebiotics-enhances-the-survival-and-the-stress-response-of-lactobacillus-rhamnosus-strains-in-simulated-gastrointestinal-transit
#17
Mariantonietta Succi, Patrizio Tremonte, Gianfranco Pannella, Luca Tipaldi, Autilia Cozzolino, Rossana Romaniello, Elena Sorrentino, Raffaele Coppola
In our study, we dwelled upon combinations of lactobacilli/prebiotics, considering four different strains belonging to the Lactobacillus rhamnosus species, including Lactobacillus rhamnosus GG (LGG), and different prebiotics often found in commercial synbiotic products, such as inulin, lactulose and polyols mannitol and sorbitol. In the first step of the research, the survival, the growth kinetic parameters and the protein expression of Lb. rhamnosus strains cultivated in presence of the different prebiotics as a unique carbon source were evaluated...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28656129/the-effects-of-synbiotic-bifidobacterium-lactis-b94-plus-inulin-addition-on-standard-triple-therapy-of-helicobacter-pylori-eradication-in-children
#18
Gonca Handan Ustundag, Halime Altuntas, Yasemin Dilek Soysal, Furuzan Kokturk
AIM: The aim of this study is to evaluate the effects of the synbiotic Bifidobacterium lactis B94 plus inulin addition to the standard triple therapy on Helicobacter pylori (H. pylori) infection eradication rates. METHODS: Children aged 6-16 years who had biopsy proven H. pylori infection were randomly classified into two groups. The first group received the standard triple therapy consisting of amoxicillin + clarithromycin + omeprazole. The second group was treated with the standard triple therapy and Bifidobacterium lactis B94 (5 × 10(9) CFU/dose) plus inulin (900 mg) for 14 days, concurrently...
2017: Canadian Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28656099/effects-of-synbiotic-food-consumption-on-serum-minerals-liver-enzymes-and-blood-pressure-in-patients-with-type-2-diabetes-a-double-blind-randomized-cross-over-controlled-clinical-trial
#19
Zatollah Asemi, Mohammad Hossein Aarabi, Mohammad Hajijafari, Sabihe-Alsadat Alizadeh, Reza Razzaghi, Majid Mazoochi, Ahmad Esmaillzadeh
BACKGROUND: This research was to examine the effects of synbiotic intake on minerals, liver enzymes, and blood pressure in patients with type 2 diabetes (T2D). METHODS: This randomized, cross-over clinical trial was performed among 62 diabetic patients. Persons were randomly assigned to intake either a synbiotic (n = 62) or a control food (n = 62) for 6 weeks. A 3-week washout period was applied following which persons were crossed over to the alternate intervention arm for an additional 6 weeks...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28653930/identification-and-growth-optimization-of-a-marine-bacillus-dk1-sa11-having-potential-of-producing-broad-spectrum-antimicrobial-compounds
#20
Muhammad Naseem Khan, Hong Lin, Meng Li, Jingxue Wang, Zulfiqar Ali Mirani, Seema Ismat Khan, Muhammad Aslam Buzdar, Imran Ali, Khalid Jamil
Control of harmful bacteria in food, aquaculture, pharmaceuticals, agriculture, hospitals and recreation water pools are of great global concern. Marine bacteria are an enormous source of bio-controlling agents. The aim of this study was to identify and optimize the growth conditions including effect of different biotic and abiotic factors on antimicrobial activity of strain DK1-SA11 isolated from Qingdao Bay of China Yellow Sea. Microscopic characterization, API® 20E and 50 CHB kit base carbohydrates utilization, 16S rDNA and DNA gyrB gene sequencing studies identified the bacterium as Bacillus subtilis subsp...
May 2017: Pakistan Journal of Pharmaceutical Sciences
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