keyword
MENU ▼
Read by QxMD icon Read
search

near infrared spectroscopy muscle oxygen

keyword
https://www.readbyqxmd.com/read/28925890/the-use-of-hemodynamic-and-cerebral-monitoring-to-study-pharmacodynamics-in-neonates
#1
A Smits, L Thewissen, A Dereymaeker, E Dempsey, A Caicedo, Gunnar Naulaers
BACKGROUND: Drugs acting on the cardiovascular and central nervous system often display relatively fast clinical responses, which may differ in neonates compared to children and adults. Introduction of bedside monitoring tools might be of additional value in the pharmacodynamic (PD) assessment of such drugs in neonates. METHODS: We aim to provide an overview of the frequently used monitoring tools to assess drug effects on the hemodynamic status as well as the cerebral circulation, oxygenation and cerebral metabolism in neonates...
September 18, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28877871/comparative-nmr-and-nirs-analysis-of-oxygen-dependent-metabolism-in-exercising-finger-flexor-muscles
#2
David Bendahan, Benjamin Chatel, Thomas Jue
Muscle contraction requires the physiology to adapt rapidly to meet the surge in energy demand. To investigate the shift in metabolic control, especially between oxygen and metabolism, researchers often depend on near infrared spectroscopy (NIRS) to measure non-invasively the tissue O2 Because NIRS detects the overlapping myoglobin (Mb) and hemoglobin (Hb) signals in muscle, interpreting the data as an index of cellular or vascular O2 requires deconvoluting the relative contribution. Currently, many in the NIRS field ascribe the signal to Hb...
September 6, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28872527/muscle-microvascular-blood-flow-oxygenation-ph-and-perfusion-pressure-decrease-in-simulated-acute-compartment-syndrome
#3
Sravya T Challa, Alan R Hargens, Amarachi Uzosike, Brandon R Macias
BACKGROUND: The current gold standard for diagnosing acute compartment syndrome (ACS) is an assessment of clinical signs, invasive measurement of intramuscular pressure (IMP), and measurement of local perfusion pressure. However, IMP measurements have several shortcomings, including pain, risk of infection, risk of technique error, plugging of the catheter tip, lack of consensus on the diagnostic pressure threshold, and lack of specificity and sensitivity. The objective of this study was to evaluate muscle hemodynamics, oxygenation, and pH as diagnostic parameters in a human model of ACS...
September 6, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28841267/effects-of-respiratory-muscle-work-on-respiratory-and-locomotor-blood-flow-during-exercise
#4
Paolo B Dominelli, Bruno Archiza, Andrew H Ramsook, Reid A Mitchell, Carli M Peters, Yannick Molgat-Seon, William R Henderson, Michael S Koehle, Robert Boushel, A William Sheel
Manipulating the work of breathing (WOB) during near-maximal exercise influences leg blood flow, but the effects on respiratory muscle blood flow are equivocal. We sought to simultaneously assess leg and respiratory muscle blood flow during intense exercise while manipulating WOB. We hypothesized that: (i) increasing the WOB would increase respiratory muscle blood flow and decrease leg blood flow, and (ii) decreasing the WOB would decrease respiratory muscle blood flow and increase leg blood flow. Eight healthy subjects (n = 5 m, n = 3 W) performed a maximal cycle test (Day 1) and a series of constant-load exercise trials at 90% of peak work rate (Day 2)...
August 25, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28819006/increased-tissue-oxygenation-explains-the-attenuation-of-hyperaemia-upon-repetitive-pneumatic-compression-of-the-lower-leg
#5
Alessandro Messere, Gianluca Ceravolo, Walter Franco, Daniela Maffiodo, Carlo Ferraresi, Silvestro Roatta
Aim The rapid hyperaemia evoked by muscle compression is short-lived and was recently shown to undergo a rapid decrease even in spite of continuing mechanical stimulation. The present study aims at investigating the mechanisms underlying this attenuation which include local metabolic mechanisms, desensitization of mechano-sensitive pathways, and reduced efficacy of the muscle pump. Methods In 10 healthy subjects short sequences of mechanical compressions (n=3-6; 150 mmHg) of the lower leg were delivered at different inter-stimulus intervals (ranging from 20 to 160 s) through a customized pneumatic device...
August 17, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28819005/blood-pressure-and-leg-deoxygenation-are-exaggerated-during-treadmill-walking-in-patients-with-peripheral-artery-disease
#6
Amanda J Miller, J Carter Luck, Danielle Jin-Kwang Kim, Urs A Leuenberger, David N Proctor, Lawrence I Sinoway, Matthew D Muller
The purpose of this study was to investigate blood pressure (BP) and leg skeletal muscle oxygen saturation (SmO2) during treadmill walking in patients with peripheral artery disease (PAD) and healthy subjects. Eight PAD patients (66 ± 3 years, 1 female) and eight healthy subjects (65 ± 2 years, 1 female) walked on a treadmill at 2 miles/hour. The incline increased by 2% every 2 minutes from 0% to 15% or until maximal discomfort. BP was measured every 2 min with an auscultatory cuff. Heart rate (HR) was recorded continuously with an electrocardiogram...
August 17, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28782598/physiological-and-performance-effects-of-nitrate-supplementation-during-roller-skiing-in-normoxia-and-normobaric-hypoxia
#7
Linn Nybäck, Caroline Glännerud, Gustav Larsson, Eddie Weitzberg, Oliver Michael Shannon, Kerry McGawley
The present study examined the effects of acute nitrate (NO3(-)) supplementation ingested in the form of concentrated beetroot juice on cross-country roller-ski performance in normoxia (N) and normobaric hypoxia (H). Eight competitive cross-country skiers (five males: age 22 ± 3 years, V·O2max 71.5 ± 4.7 mL kg(-1)·min(-1); three females: age 21 ± 1 years, V·O2max 58.4 ± 2.5 mL kg(-1)·min(-1)) were supplemented with a single dose of NO3(-)-rich beetroot juice (BRJ, ∼13 mmol NO3(-)) or a NO3(-)-depleted placebo (PL, ∼0 mmol NO3(-)) and performed 2 x 6-min submaximal exercise bouts and a 1000-m time-trial (TT) on a treadmill in N (20...
August 4, 2017: Nitric Oxide: Biology and Chemistry
https://www.readbyqxmd.com/read/28753391/differences-in-forearm-strength-endurance-and-hemodynamic-kinetics-between-male-boulderers-and-lead-rock-climbers
#8
S Fryer, K J Stone, J Sveen, T Dickson, V España-Romero, D Giles, J Baláš, L Stoner, N Draper
This study examined differences in the oxygenation kinetics and strength and endurance characteristics of boulderers and lead sport climbers. Using near infrared spectroscopy, 13-boulderers, 10-lead climbers, and 10-controls completed assessments of oxidative capacity index and muscle oxygen consumption (mV˙O2) in the flexor digitorum profundus (FDP), and extensor digitorum communis (EDC). Additionally, forearm strength (maximal volitional contraction MVC), endurance (force-time integral FTI at 40% MVC), and forearm volume (FAV and ΔFAV) was assessed...
July 28, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/28693932/muscle-tissue-saturation-compared-with-muscle-tissue-perfusion-during-low-blood-flows-an-experimental-study
#9
Sisse Anette Thomassen, Benedict Kjærgaard, Aage Kristian Olsen Alstrup, Ole Lajord Munk, Jørgen Frøkiær, Anders Larsson, Bodil Steen Rasmussen
OBJECTIVE: To investigate whether changes in muscle tissue perfusion measured with positron emission tomography would be reflected by parallel changes in muscle tissue oxygen saturation (StO2) measured using near-infrared spectroscopy during high and low blood flow levels achieved using cardiopulmonary bypass (CPB) in an animal model. DESIGN: A prospective, randomized study. SETTING: Research laboratory, single institution. PARTICIPANTS: Eight pigs (69-71 kg)...
March 22, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/28685454/delayed-onset-of-reoxygenation-in-inactive-muscles-after-high-intensity-exercise
#10
Takuya Osawa, Keisuke Shiose, Hideyuki Takahashi
Oxygenation, measured by near-infrared spectroscopy (NIRS), in inactive muscles decreases during high-intensity exercise because of the decrease of oxygen supply. However, there have been few reports regarding recovery of inactive muscle oxygenation after exercise. This study was performed to examine reoxygenation in the biceps brachii muscle (BB) after supramaximal cycling exercise. Six active young male volunteers (age: 22  ±  3 years, peak oxygen uptake (VO2peak): 53.8  ±  5.4 mL/kg/min, mean  ±  S...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28685453/tissue-blood-volume-parameters-measured-by-continuous-wave-and-spatially-resolved-nirs-show-different-changes-during-prolonged-cycling-exercise
#11
Takuya Osawa, Keisuke Shiose, Hideyuki Takahashi
Near-infrared spectroscopy (NIRS) shows two types of tissue blood volume (BV) parameters: the total hemoglobin concentration (cHb; assessed by continuous-wave NIRS) and the normalized tissue hemoglobin index (nTHI; evaluated by spatially resolved NIRS). This study was performed to investigate the differences between cHb and nTHI, estimated by calibration using acute reduction of BV at the onset of exercise. Seven active male volunteers (age: 22  ±  4 years) performed a prolonged (60-min) cycling exercise test at 65% or 70% of the peak oxygen uptake...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28685425/multi-site-measurements-of-muscle-o2-dynamics-during-cycling-exercise-in-early-post-myocardial-infarction
#12
Shun Takagi, Ryotaro Kime, Norio Murase, Masatsugu Niwayama, Takuya Osada, Toshihito Katsumura
The aim of this study was to compare the muscle oxygen dynamics between early post-myocardial infarction (n = 12; MI) and age-matched elderly subjects without MI (n = 12; CON) in several leg muscles during ramp cycling exercise. Muscle oxygen saturation (SmO2), deoxygenated-hemoglobin concentration (∆deoxy-Hb), and total-hemoglobin concentration (∆total-Hb) were monitored continuously at the distal site of vastus lateralis (VLd), proximal site of the vastus lateralis (VLp), rectus femoris (RF), vastus medialis (VM), gastrocnemius medialis (GM), and tibialis anterior (TA) muscles by near infrared spatial resolved spectroscopy...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28685423/dorsiflexor-muscle-oxygenation-during-low-moderate-and-submaximal-sustained-isometric-contraction
#13
Adkham Paiziev, Martin Wolf, Fikrat Kerimov
Sustained isometric contractions of skeletal muscles produce intramuscular pressures that lead to blood flow restriction. Thus, we have the paradox of rising O2 demand due to muscle activity and at the same time reduced blood flow. The aim was to assess muscle oxygenation during sustained isometric low (30%), moderate (60%) and submaximal [90% of maximal voluntary contraction (MVC)] contraction of the dorsiflexor muscle. Experiments were conducted on the dominant (right) leg of 8 male students (age 19 ± 2 years, weight 75 ± 6 kg)...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28680113/oxygen-consumption-of-gastrocnemius-medialis-muscle-during-submaximal-voluntary-isometric-contractions-with-and-without-preceding-stretch
#14
F K Paternoster, D Hahn, F Stöcker, A Schwirtz, W Seiberl
After an active muscle stretch, maintaining a certain amount of force in the following isometric phase is accompanied by less muscle activation compared to an isometric contraction without preceding active stretch at the corresponding muscle length. This reduced muscle activation might be related to reduced metabolic costs, such as the oxidative metabolism. Hence, the aim of this study was to clarify if mechanisms associated with stretch-induced activation reduction (AR) also influence oxygen consumption of voluntary activated human muscles after active stretch...
July 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28647868/effects-of-high-altitude-exposure-on-supraspinal-fatigue-and-corticospinal-excitability-and-inhibition
#15
Mathieu Marillier, Pierrick J Arnal, Thibault Le Roux Mallouf, Thomas Rupp, Guillaume Y Millet, Samuel Verges
PURPOSE: While acute hypoxic exposure enhances exercise-induced central fatigue and can alter corticospinal excitability and inhibition, the effect of prolonged hypoxic exposure on these parameters remains to be clarified. We hypothesized that 5 days of altitude exposure would (i) normalize exercise-induced supraspinal fatigue during isolated muscle exercise to sea level (SL) values and (ii) increase corticospinal excitability and inhibition. METHODS: Eleven male subjects performed intermittent isometric elbow flexions at 50% of maximal voluntary contraction to task failure at SL and after 1 (D1) and 5 (D5) days at 4350 m...
August 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28622081/effects-of-inspiratory-muscle-training-in-professional-women-football-players-a-randomized-sham-controlled-trial
#16
Bruno Archiza, Daniela Kuguimoto Andaku, Flávia Cristina Rossi Caruso, José Carlos Bonjorno, Cláudio Ricardo de Oliveira, Paula Angélica Ricci, André Capaldo do Amaral, Stela Márcia Mattiello, Cleiton Augusto Libardi, Shane A Phillips, Ross Arena, Audrey Borghi-Silva
This study was conducted to determine the effects of inspiratory muscle training (IMT) on respiratory and peripheral muscles oxygenation during a maximal exercise tolerance test and on repeated-sprint ability (RSA) performance in professional women football players. Eighteen athletes were randomly assigned to one of the following groups: SHAM (n = 8) or IMT (n = 10). After a maximal incremental exercise test, all participants performed (on a different day) a time-to-exhaustion (Tlim) test. Peripheral and respiratory muscles oxygenation by near-infrared spectroscopy, breath-by-breath ventilatory and metabolic variables, and blood lactate concentration were measured...
June 16, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28617704/greater-oxidative-capacity-in-primary-myotubes-from-endurance-trained-women
#17
Timothy D Heden, Terence E Ryan, Patrick J Ferrara, Robert C Hickner, Patricia M Brophy, P Darrell Neufer, Joseph M McClung, Katsuhiko Funai
PURPOSE: Exercise training promotes skeletal muscle mitochondrial biogenesis and an increase in maximal oxygen consumption. Primary myotubes retain some metabolic properties observed in vivo but it is unknown whether this includes exercise-induced mitochondrial adaptations. The goal of this study was to test if primary myotubes from exercise-trained women have higher mitochondrial content and maximal oxygen consumption compared to untrained women. METHODS: Six trained and nine untrained Caucasian women participated in this study...
June 14, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28616108/advances-in-basic-science-methodologies-for-clinical-diagnosis-in-female-stress-urinary-incontinence
#18
REVIEW
Marwa Abdulaziz, Emily G Deegan, Alex Kavanagh, Lynn Stothers, Denise Pugash, Andrew Macnab
We provide an overview of advanced imaging techniques currently being explored to gain greater understanding of the complexity of stress urinary incontinence (SUI) through better definition of structural anatomic data. Two methods of imaging and analysis are detailed for SUI with or without prolapse: 1) open magnetic resonance imaging (MRI) with or without the use of reference lines; and 2) 3D reconstruction of the pelvis using MRI. An additional innovative method of assessment includes the use of near infrared spectroscopy (NIRS), which uses non-invasive photonics in a vaginal speculum to objectively evaluate pelvic floor muscle (PFM) function as it relates to SUI pathology...
June 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28607132/impaired-muscle-oxygenation-and-elevated-exercise-blood-pressure-in-hypertensive-patients-links-with-vascular-stiffness
#19
Konstantina Dipla, Areti Triantafyllou, Nikolaos Koletsos, Stavros Papadopoulos, Vasileios Sachpekidis, Ioannis S Vrabas, Eugenia Gkaliagkousi, Andreas Zafeiridis, Stella Douma
This study examined in vivo (1) skeletal muscle oxygenation and microvascular function, at rest and during handgrip exercise, and (2) their association with macrovascular function and exercise blood pressure (BP), in newly diagnosed, never-treated patients with hypertension and normotensive individuals. Ninety-one individuals (51 hypertensives and 40 normotensives) underwent office and 24-hour ambulatory BP, arterial stiffness, and central aortic BP assessment, followed by a 5-minute arterial occlusion and a 3-minute submaximal handgrip exercise...
August 2017: Hypertension
https://www.readbyqxmd.com/read/28585358/muscle-microcirculation-alterations-and-relation-to-dipping-status-in-newly-diagnosed-untreated-patients-with-arterial-hypertension-a-pilot-study
#20
Georgios Tzanis, Stavros Dimopoulos, Chris Manetos, Eleni Koroboki, Efstathios Manios, Ioannis Vasileiadis, Nikolaos Zakopoulos, Serafim Nanas
OBJECTIVE: The importance of abnormalities observed in the microcirculation of patients with arterial hypertension (AH) is being increasingly recognized. The authors aimed to evaluate skeletal muscle microcirculation in untreated, newly diagnosed hypertensive patients with Near Infrared Spectroscopy (NIRS), a non-invasive method that evaluates microcirculation. METHODS: We evaluated 34 subjects, 17 patients with AH (13 males, 49±13y, BMI: 26±2 kg/m(2) ) and 17 healthy controls (12 males, 49±15y, BMI: 25±3 kg/m(2) )...
June 5, 2017: Microcirculation: the Official Journal of the Microcirculatory Society, Inc
keyword
keyword
28800
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"