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Preconception

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https://www.readbyqxmd.com/read/27923193/preconception-personality-disorder-and-antenatal-maternal-mental-health-a-population-based-cohort-study
#1
Charlotte Hudson, Elizabeth Spry, Rohan Borschmann, Denise Becker, Paul Moran, Craig Olsson, Carolyn Coffey, Helena Romaniuk, Jordana K Bayer, George C Patton
BACKGROUND: Prior anxiety and depression have been identified as risk factors for maternal perinatal mental health problems, but other preconception mental disorders have not been prospectively examined. This study investigated prospectively whether women with preconception personality disorder have increased rates of antenatal anxiety and/or depressive symptoms. METHODS: 244 women in a population cohort were assessed for personality disorder at age 24 using the Standardised Assessment of Personality...
November 29, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27918586/impact-of-preconception-micronutrient-supplementation-on-anemia-and-iron-status-during-pregnancy-and-postpartum-a-randomized-controlled-trial-in-rural-vietnam
#2
Phuong H Nguyen, Melissa Young, Ines Gonzalez-Casanova, Hoa Q Pham, Hieu Nguyen, Truong V Truong, Son V Nguyen, Kimberly B Harding, Gregory A Reinhart, Reynaldo Martorell, Usha Ramakrishnan
OBJECTIVE: Preconception micronutrient interventions may be a promising approach to reduce anemia and iron deficiency during pregnancy, but currently we have limited data to inform policies. We evaluated whether providing additional pre-pregnancy weekly iron-folic acid (IFA) or multiple micronutrient (MM) supplements compared to only folic acid (FA) improves iron status and anemia during pregnancy and early postpartum. METHODS: We conducted a double blind randomized controlled trial in which 5011 Vietnamese women were provided with weekly supplements containing either only 2800 μg FA (control group), IFA (60 mg Fe and 2800 μg FA) or MM (15 micronutrients with similar amounts of IFA)...
2016: PloS One
https://www.readbyqxmd.com/read/27906972/selective-serotonin-reuptake-inhibitor-ssri-antidepressants-in-pregnancy-and-congenital-anomalies-analysis-of-linked-databases-in-wales-norway-and-funen-denmark
#3
Sue Jordan, Joan K Morris, Gareth I Davies, David Tucker, Daniel S Thayer, Johannes M Luteijn, Margery Morgan, Ester Garne, Anne V Hansen, Kari Klungsøyr, Anders Engeland, Breidge Boyle, Helen Dolk
BACKGROUND: Hypothesised associations between in utero exposure to selective serotonin reuptake inhibitors (SSRIs) and congenital anomalies, particularly congenital heart defects (CHD), remain controversial. We investigated the putative teratogenicity of SSRI prescription in the 91 days either side of first day of last menstrual period (LMP). METHODS AND FINDINGS: Three population-based EUROCAT congenital anomaly registries- Norway (2004-2010), Wales (2000-2010) and Funen, Denmark (2000-2010)-were linked to the electronic healthcare databases holding prospectively collected prescription information for all pregnancies in the timeframes available...
2016: PloS One
https://www.readbyqxmd.com/read/27905191/race-and-ethnicity-and-preconception-folic-acid-supplement-use-among-pregnant-women-in-georgia-prams-2009-to-2011
#4
Ayesha Mukhtar, Michael R Kramer, Godfrey P Oakley, Vijaya Kancherla
BACKGROUND: The United States Public Health Service recommends that all women of reproductive age consume 400 μg of folic acid daily to prevent major neural tube defects. Hispanics have the highest prevalence of neural tube defects compared with other race/ethnic groups. We studied prevalence of preconception folic acid supplement use, and its association with race/ethnicity among pregnant women in Georgia. METHODS: Using state-wide population-based data from 2009 to 2011 Georgia Pregnancy Risk Assessment Monitoring System, we examined the prevalence of preconception folic acid supplement use among pregnant women aged 18 to 45 years...
December 1, 2016: Birth Defects Research. Part A, Clinical and Molecular Teratology
https://www.readbyqxmd.com/read/27904635/evaluation-of-reproductive-health-indicators-in-women-affected-by-east-azarbaijan-earthquake-on-august-2012
#5
Farideh Bahmanjanbeh, Shahnaz Kohan, Mohammad Hossein Yarmohammadian, Abbas Haghshenas
BACKGROUND: Ignoring reproductive health services during natural disasters leads to some negative consequences such as reduced access to contraceptive methods, sexual disorders, and pregnancy complications. Despite previous researches, there is still more need for research on this area of health. This study attempts to identify the indicators of reproductive health in the women affected by the East Azarbaijan earthquake on August 2012. MATERIALS AND METHODS: In this descriptive study, reproductive health information pertaining to the years before, during, and after the earthquake were collected and compared in the health centers of the three affected cities including Ahar, Heriss, and Varzaghan as well as the health and forensics centers of the East Azarbaijan province in Iran by census method...
September 2016: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/27903519/dairy-intake-and-fecundability-in-2-preconception-cohort-studies
#6
Lauren A Wise, Amelia K Wesselink, Ellen M Mikkelsen, Heidi Cueto, Kristen A Hahn, Kenneth J Rothman, Katherine L Tucker, Henrik Toft Sørensen, Elizabeth E Hatch
BACKGROUND: Animal studies have shown that a high intake of galactose, a breakdown product of lactose, increases ovarian toxicity. Few epidemiologic studies, to our knowledge, have examined the association between dairy intake and fertility, and they have had conflicting findings. OBJECTIVE: We prospectively evaluated dairy intake in relation to fecundability among women who were planning for pregnancy. DESIGN: Data were derived from preconception cohort studies in Denmark (Snart Foraeldre) and North America [PRESTO (Pregnancy Study Online)] in which women completed a validated food-frequency questionnaire 10 d after enrollment...
November 30, 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27901552/diagnosis-and-management-of-hyperthyroidism-in-pregnancy-a-review
#7
Jennifer Renae King, Ruben Lachica, Richard H Lee, Martin Montoro, Jorge Mestman
Importance: Hyperthyroidism has important implications for pregnancy, affecting both mother and fetus. Appropriate maternal and fetal management iscritical to avoiding adverse pregnancy outcomes and requires a multidisciplinary approach. Objective: To describe maternal diagnosis and management of hyperthyroidism, across all stages of pregnancy. In addition, to review clinical signs of fetal thyroid dysfunction due to maternal Graves disease and discuss management considerations...
November 2016: Obstetrical & Gynecological Survey
https://www.readbyqxmd.com/read/27892699/genetics-of-consanguinity-and-inbreeding-in-health-and-disease
#8
Mohd Fareed, Mohammad Afzal
CONTEXT: Inbreeding increases the level of homozygotes for autosomal recessive disorders and is the major objective in clinical studies. The prevalence of consanguinity and the degree of inbreeding vary from one population to another depending on ethnicity, religion, culture and geography. Global epidemiological studies have revealed that consanguineous unions have been significantly associated with increased susceptibility to various forms of inherited diseases Objective: The study aimed to determine the role of consanguinity in human health and to highlight the associated risks for various diseases or disorders...
November 28, 2016: Annals of Human Biology
https://www.readbyqxmd.com/read/27891779/using-insurance-claims-data-to-identify-and-estimate-critical-periods-in-pregnancy-an-application-to-antidepressants
#9
Elizabeth C Ailes, Regina M Simeone, April L Dawson, Emily E Petersen, Suzanne M Gilboa
BACKGROUND: Health insurance claims are a rich data source to examine medication use in pregnancy. Our objective was to identify pregnant women, their pregnancy outcomes, and date of their last menstrual period (LMP), and to estimate antidepressant dispensations in pregnancy. METHODS: From a literature search, we identified diagnosis and procedure codes indicating the end of a pregnancy. Using Truven Health MarketScan(®) Commercial Claims and Encounters Databases, we identified all inpatient admissions and outpatient service claims with these codes...
November 2016: Birth Defects Research. Part A, Clinical and Molecular Teratology
https://www.readbyqxmd.com/read/27889275/preconceptions-about-the-infection-process-among-prenursing-students
#10
Thomas A Dombrowsky, Linda Frye
Two hundred seven prenursing students in a large university-based nursing college participated in a study about their preconceptions concerning the infection process. Most students had a poor understanding of the distinction between bacteria and viruses and had little knowledge about the immune system or the mechanism of action of antibiotics. Instructors can use knowledge of student preconceptions to create more relevant learning experiences.
November 24, 2016: American Journal of Infection Control
https://www.readbyqxmd.com/read/27889099/eating-disorders-in-the-context-of-preconception-care-fertility-specialists-knowledge-attitudes-and-clinical-practices
#11
Iolanda S Rodino, Susan M Byrne, Katherine A Sanders
OBJECTIVE(S): To gauge fertility specialists' knowledge, clinical practices, and training needs in regard to eating disorders. DESIGN: Cross-sectional study. SETTINGS: Fertility clinics. PARTICIPANTS: Eighty Australian and New Zealand fertility specialists who were members of the Fertility Society of Australia. INTERVENTION(S): None. MAIN OUTCOME MEASURES(S): Responses to an anonymously completed online questionnaire...
November 23, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27881182/research-prevalence-of-neural-tube-defects-khartoum-sudan-august-2014-july-2015
#12
Ilham M Omer, Osman M Abdullah, Inaam N Mohammed, Lina A Abbasher
BACKGROUND: Neural tube defects (NTDs) are birth defects that results from failure of the neural tube to develop properly during early pregnancy. METHODS: We studied the prevalence of neural tube defects in newborns admitted to the NICU in Soba University and Omdurman Maternity hospitals, during the period 1st August 2014 to 31st July 2015. A cross-sectional hospital based study, involved all newborns with any type of neural tube defect admitted to the NICU in the study area during the study period...
November 24, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27876231/paternal-preconception-alcohol-exposure-imparts-intergenerational-alcohol-related-behaviors-to-male-offspring-on-a-pure-c57bl-6j-background
#13
Gregory R Rompala, Andrey Finegersh, Michelle Slater, Gregg E Homanics
While alcohol use disorder (AUD) is a highly heritable condition, the basis of AUD in families with a history of alcoholism is difficult to explain by genetic variation alone. Emerging evidence suggests that parental experience prior to conception can impact inheritance of complex behaviors in offspring via non-genomic (epigenetic) mechanisms. For instance, male C57BL/6J (B6) mice exposed to chronic intermittent vapor ethanol (CIE) prior to mating with Strain 129S1/SvImJ ethanol-naïve females produce male offspring with reduced ethanol drinking preference, increased ethanol sensitivity, and increased BDNF expression in the ventral tegmental area (VTA)...
November 5, 2016: Alcohol
https://www.readbyqxmd.com/read/27873033/stability-of-bisexual-behavior-and-extent-of-viral-bridging-behavior-among-men-who-have-sex-with-men-and-women
#14
M Reuel Friedman, Ron Stall, Michael Plankey, Steve Shoptaw, A L Herrick, Pamela J Surkan, Linda Teplin, Anthony J Silvestre
Bisexual men experience significant health disparities likely related to biphobia. Biphobia presents via several preconceptions, including that bisexuality is transitory, and that bisexual men act as viral bridges between men who have sex with men and heterosexual populations. We analyzed data from a prospective cohort of gay and bisexual men, the Multicenter AIDS Cohort Study, to test these preconceptions. Men reporting both male and female sexual partners (MSMW) between 2002 and 2009 (n = 111) were classified as behaviorally bisexual...
November 21, 2016: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/27871260/are-early-first-trimester-weights-valid-proxies-for-preconception-weight
#15
Rebecca A Krukowski, Delia S West, Marisha DiCarlo, Kartik Shankar, Mario A Cleves, Marie E Saylors, Aline Andres
BACKGROUND: An accurate estimate of preconception weight is necessary for providing a gestational weight gain range based on the Institute of Medicine's guidelines; however, an accurate and proximal preconception weight is not available for most women. We examined the validity of first trimester weights for estimating preconception body mass index category. METHODS: Under identical measurement conditions, preconception weight and two first trimester weights (i.e...
November 21, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27870155/timing-of-maternal-exposure-and-fetal-sex-determine-the-effects-of-low-level-chemical-mixture-exposure-on-the-fetal-neuroendocrine-system-in-sheep
#16
M Bellingham, P A Fowler, E S MacDonald, B Mandon-Pepin, C Cotinot, S Rhind, R M Sharpe, N P Evans
We have shown that continuous maternal exposure to the complex mixture of environmental chemicals (ECs) found in human biosolids (sewage sludge), disrupts mRNA expression of genes crucial for development and long-term regulation of hypothalamo-pituitary gonadal (HPG) function in sheep. This study investigated whether exposure to ECs only during preconceptional period or only during pregnancy perturbed key regulatory genes within the hypothalamus and pituitary gland and whether these effects were different from chronic (life-long) exposure to biosolid ECs...
November 21, 2016: Journal of Neuroendocrinology
https://www.readbyqxmd.com/read/27865567/preconceptional-and-perinatal-exposure-to-traffic-related-air-pollution-and-eczema-in-preschool-children
#17
Chan Lu, Linjing Deng, Cuiyun Ou, Hong Yuan, Xiang Chen, Qihong Deng
BACKGROUND: Evidence linking prenatal exposure to outdoor air pollution with eczema in early childhood is scare, and the role of components of air pollution and exposure timing remains unclear. OBJECTIVES: We investigated the association between exposure to air pollution during preconceptional and perinatal period and the risk of eczema in preschool children. METHODS: We conducted a prospective cohort study of 2598 children aged 3-6 years in Changsha, China...
November 9, 2016: Journal of Dermatological Science
https://www.readbyqxmd.com/read/27857015/-effects-of-web-based-preconception-health-promotion-program-for-couples-about-to-be-married
#18
Nam Joo Je, So Young Choi
PURPOSE: This study was done to develop a Web-based preconception health promotion program to improve preconception health promotion awareness, perceived benefits, perceived self-efficacy and health behavior, and to reduce perceived barriers in couples about to be married. METHODS: Participants were assigned to the experimental group (n=26 couples) or control group (n=25 couples). This program was comprised of a six hour Web-based lecture series which was given to the experimental group over a four week period...
October 2016: Journal of Korean Academy of Nursing
https://www.readbyqxmd.com/read/27855514/trail-blazing-or-jam-session-towards-a-new-concept-of-clinical-decision-making
#19
Torsten Risør
Clinical decision-making (CDM) is key in learning to be a doctor as the defining activity in their clinical work. CDM is often portrayed in the literature as similar to 'trail blazing'; the doctor as the core agent, clearing away obstacles on the path towards diagnosis and treatment. However, in a fieldwork of young doctors in Denmark, it was difficult connect their practice to this image. This paper presents the exploration of this discrepancy in the heart of medical practice and how an alternative image emerged; that of a 'jam session'...
November 17, 2016: Anthropology & Medicine
https://www.readbyqxmd.com/read/27855048/-relationship-between-the-level-of-maternal-glycated-hemoglobin-and-fetal-hypertrophic-cardiomyopathy
#20
Karla Lucía Sánchez-Martínez, Luis Fernando Oseguera-Torres, Joel Ávalos-Nuño
BACKGROUND: Diabetes mellitus is a metabolic disorder commonly associated with pregnancy. It is shown that as the management of diabetes during pregnancy is optimized, decreases the frequency and severity of fetal and neonatal complications. The aim of this paper is to identify the relation between the level of maternal glycated hemoglobin and fetal hypertrophic cardiomyopathy. METHODS: An analitytic cross-sectional study was conducted. It included patients with single pregnancy of 28-37 weeks diagnosed with gestational or preconception diabetes mellitus...
2016: Revista Médica del Instituto Mexicano del Seguro Social
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