Brian M Ilfeld, Cameron R Smith, Alparslan Turan, Edward R Mariano, Matthew E Miller, Rick L Fisher, Andrea M Trescot, Steven P Cohen, James C Eisenach, Daniel I Sessler, J David Prologo, Edward J Mascha, Liu Liu, Rodney A Gabriel
BACKGROUND: The smallest meaningful improvement in pain scores (minimal clinically important difference [MCID]) after an analgesic intervention is essential information when both interpreting published data and designing a clinical trial. However, limited information is available for patients with chronic pain conditions, and what is published is derived from studies involving pharmacologic and psychological interventions. We here calculate these values based on data collected from 144 participants of a previously published multicenter clinical trial investigating the effects of a single treatment with percutaneous cryoneurolysis...
March 14, 2024: Anesthesia and Analgesia