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https://www.readbyqxmd.com/read/28332712/-for-beauty-is-nothing-but-the-barely-endurable-onset-of-terror-outline-of-a-general-psychoanalytic-aesthetics
#1
Sebastian Leikert
Even close to 80 years after Freud's words that psychoanalysis "has scarcely anything to say about beauty" (Freud, Civilization and its Discontents, SE 21, p. 82) the question of a specific psychoanalytic aesthetic is still faced with a deficit in theory. Since aesthetics is related to Aisthesis, the Greek word for 'perception', a psychoanalytic aesthetic can solely emerge from a psychoanalysis of perceptive structures. The term 'kinaesthetic semantic' is introduced in order to exemplify via music how perceptive experiences must be structured for them to be experienced as beautiful...
March 23, 2017: International Journal of Psycho-analysis
https://www.readbyqxmd.com/read/28327300/rbaltmip-a-recombinant-alpha-type-myotoxin-inhibitor-from-bothrops-alternatus-rhinocerophis-alternatus-snake-as-a-potential-candidate-to-complement-the-antivenom-therapy
#2
Norival A Santos-Filho, Tiago S Sousa, Johara Boldrini-França, Ludier K Santos-Silva, Danilo L Menaldo, Flávio Henrique-Silva, Adélia C O Cintra, Helen J Laure, Carla C N Mamede, Fábio Oliveira, Thalita B Riul, Marcelo Dias-Baruffi, José C Rosa, Suely V Sampaio
Phospholipase A2 inhibitors (PLIs) are important targets in the search and development of new drugs. This study aimed at evaluating the potential of an alpha-type phospholipase A2 inhibitor from Bothrops alternatus (Rhinocerophis alternatus) snake in its recombinant form (rBaltMIP) to complement the conventional antivenom therapy. Biochemical experiments showed that rBaltMIP presented pI 5.8 and molecular masses of ∼21 kDa by SDS-PAGE and 19.57 kDa by MALDI/TOF MS. After tryptic peptides sequencing, the results were compared with other PLIs available in databases, showing 100% identity between rBaltMIP and its native inhibitor BaltMIP and from 92% to 96% identity with other inhibitors...
December 15, 2016: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/28322165/anti-inflammatory-and-anti-arthritic-activity-of-different-milk-based-formulation-of-curcumin-in-rat-model
#3
Sumeet Gupta
Inflammation is the key mediator for arthritis. Plant based products are most useful for treating various disorders, but at the same time drug absorbtion is utmost important for effective therapy. The aim of the study was to find out the therapeutic concern in pharmacokinetic and pharmacodynamic parameters in an arthritis induced rat model. Carrageenan and complete Freud's adjuvant, both were used for an arthritis induction as an animal model. Five different formulations of curcumin were prepared in single toned milk, double toned milk, full fat milk, full fat milk with ghee and in an aqueous suspension...
March 20, 2017: Current Drug Delivery
https://www.readbyqxmd.com/read/28278058/the-queerness-of-the-drive
#4
Teresa de Lauretis
The view of sexuality Freud first proposed in the Three Essays on the Theory of Sexuality contains a discrepancy between the sexuality perverse and polymorphous described in the first two essays and the biologically directed, reproductive sexuality of the third essay. According to Jean Laplanche, the theorist of psychoanalysis who is Freud's closest reader and translator, the discrepancy is due to two contradictory opinions Freud apparently held at different moments of his writing: one, that sexuality is exogenous, an effect of seduction by adults; two, that sexuality is endogenous, innate in the human biological organism...
February 16, 2017: Journal of Homosexuality
https://www.readbyqxmd.com/read/28275347/cognitive-training-sustainably-improves-executive-functioning-in-middle-aged-industry-workers-assessed-by-task-switching-a-randomized-controlled-erp-study
#5
Patrick D Gajewski, Gabriele Freude, Michael Falkenstein
Recently, we reported results of a cross-sectional study investigating executive functions in dependence of aging and type of work. That study showed deficits in performance and electrophysiological activity in middle-aged workers with long-term repetitive and unchallenging work. Based on these findings, we conducted a longitudinal study that aimed at ameliorating these cognitive deficits by means of a trainer-guided cognitive training (CT) in 57 further middle-aged workers with repetitive type of work from the same factory...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28272829/freud-and-the-scene-of-trauma-by-john-fletcher
#6
Ira Brenner
No abstract text is available yet for this article.
January 2017: Psychoanalytic Quarterly
https://www.readbyqxmd.com/read/28272824/ten-short-essays-on-how-trauma-is-inextricably-woven-into-psychic-life
#7
Dominique Scarfone
The author contends that it is possible to reconcile trauma and drive theories of psychopathology if we carefully examine the general notion of trauma and reexamine Freud's () theory of war neurosis and of repression itself as an elementary form of traumatic neurosis. The logic of these views follows Laplanche's reintroduction and generalization of the seduction theory in contemporary psychoanalysis.
January 2017: Psychoanalytic Quarterly
https://www.readbyqxmd.com/read/28272820/freud-and-war-edited-by-marlene-belilos
#8
Aaron H Esman
No abstract text is available yet for this article.
January 2017: Psychoanalytic Quarterly
https://www.readbyqxmd.com/read/28272818/a-model-for-integrating-actual-neurotic-or-unrepresented-states-and-symbolized-aspects-of-intrapsychic-conflict
#9
Fredric N Busch
In psychoanalytic theory, the importance of actual neuroses-considered to be devoid of psychic content-diminished as Freud and subsequent analysts focused on unconscious intrapsychic conflict. This paper explores the relationship between actual neurotic and unrepresented states, which are believed to be best addressed through attention to countertransference, intersubjectivity, and enactments rather than interpretation of intrapsychic conflict. Models suggesting how actual neurotic states and symbolized intrapsychic conflict may interact with each other and environmental stressors are described...
January 2017: Psychoanalytic Quarterly
https://www.readbyqxmd.com/read/28265351/elevated-axonal-membrane-permeability-and-its-correlation-with-motor-deficits-in-an-animal-model-of-multiple-sclerosis
#10
Gary Leung, Melissa Tully, Jonathan Tang, Shengxi Wu, Riyi Shi
BACKGROUND: It is increasingly clear that in addition to myelin disruption, axonal degeneration may also represent a key pathology in multiple sclerosis (MS). Hence, elucidating the mechanisms of axonal degeneration may not only enhance our understanding of the overall MS pathology, but also elucidate additional therapeutic targets. The objective of this study is assess the degree of axonal membrane disruption and its significance in motor deficits in EAE mice. METHODS: Experimental Autoimmune Encephalomyelitis was induced in mice by subcutaneous injection of myelin oligodendrocyte glycoprotein/complete Freud's adjuvant emulsion, followed by two intraperitoneal injections of pertussis toxin...
2017: Translational Neurodegeneration
https://www.readbyqxmd.com/read/28261798/early-and-deep-two-independent-paradigms
#11
Martine Girard
Did Winnicott replace or transform Freud's metapsychology? The author's aim is to explore more deeply the views developed in a previous paper based solely on Winnicott. Here the author draws on other studies to respond to two questions recently posed by Fulgencio concerning the meaning of the term metapsychology and the existence of a new topography in Winnicott's work. For many authors, Winnicott does not reject Freudian metapsychology and says nothing new in this field; in the field of paediatric anthropology, however, he focuses on dependence, and in the field of the living embodiment of the drives on being and self as different from ego...
March 6, 2017: International Journal of Psycho-analysis
https://www.readbyqxmd.com/read/28261796/-freud-s-speculations-in-ethnology-a-reflection-on-anthropology-s-encounter-with-psychoanalysis
#12
Patrick S Rivera
In the early 20th century, many analysts - Freud and Ernest Jones in particular - were confident that cultural anthropologists would demonstrate the universal nature of the Oedipus complex and other unconscious phenomena. Collaboration between the two disciplines, however, was undermined by a series of controversies surrounding the relationship between psychology and culture. This paper re-examines the three episodes that framed anthropology's early encounter with psychoanalysis, emphasizing the important works and their critical reception...
March 6, 2017: International Journal of Psycho-analysis
https://www.readbyqxmd.com/read/28260868/the-diagnosis-of-delirium-in-an-acute-care-hospital-in-moscow-what-does-the-pandora-s-box-contain
#13
Olga N Tkacheva, Nadezda K Runikhina, Arkadiy L Vertkin, Irina V Voronina, Natalia V Sharashkina, Elen A Mkhitaryan, Valentina S Ostapenko, Elena A Prokhorovich, Tamar Freud, Yan Press
BACKGROUND: Delirium, a common problem among hospitalized elderly patients, is not usually diagnosed by doctors for various reasons. The primary aim of this study was to evaluate the effect of a short training course on the identification of delirium and the diagnostic rate of delirium among hospitalized patients aged ≥65 years. The secondary aim was to identify the risk factors for delirium. METHODS: A prospective study was conducted in an acute-care hospital in Moscow, Russia...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28253942/delayed-fracture-healing-in-diabetics-with-distal-radius-fractures
#14
S Pscherer, G H Sandmann, S Ehnert, A K Nussler, U Stöckle, T Freude
PURPOSE OF THE STUDY Diabetics may have an increased fracture risk, depending on disease duration, quality of metabolic adjustment and extent of comorbidities, and on an increased tendency to fall. The aim of this retrospective one-centre study consisted in detecting differences in fracture healing between patients with and without diabetes mellitus. Data of patients with the most common fracture among older patients were analyzed. MATERIAL AND METHODS Classification of distal radius fractures was established according to the AO classification...
2017: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28251617/self-analysis-and-the-development-of-an-interpretation
#15
Donald Campbell
In spite of the fact that Freud's self-analysis was at the centre of so many of his discoveries, self-analysis remains a complex, controversial and elusive exercise. While self-analysis is often seen as emerging at the end of an analysis and then used as a criteria in assessing the suitability for termination, I try to attend to the patient's resistance to self-analysis throughout an analysis. I take the view that the development of the patient's capacity for self-analysis within the analytic session contributes to the patient's growth and their creative and independent thinking during the analysis, which prepares him or her for a fuller life after the formal analysis ends...
March 2, 2017: International Journal of Psycho-analysis
https://www.readbyqxmd.com/read/28248563/promoting-behavioral-change-in-psychoanalytic-treatments
#16
Fredric N Busch
One of the shibboleths of psychoanalysis is that treatment should not target behavioral change, focusing instead on gaining insight and the therapeutic relationship (Freud, 1917; 1923; Gabbard, 2014; Greenson, 1967). Such an approach is believed to be accompanied by disruptions of exploration or problematic distortions of the transference (Freud, 1917; 1923; Gabbard, 2014; Greenson, 1967). However, ignoring behavioral change can put patients at increased risk for stalemates in treatment and persistent problematic behaviors that interfere with improvement and impair relationships...
2017: Psychodynamic Psychiatry
https://www.readbyqxmd.com/read/28247936/uses-of-guilt-in-the-treatment-of-dehumanization
#17
Harvey Peskin
It is likely that under the impact of impending Nazism, aggression theory in late Freud, as presented in Civilization and its Discontents (1930), left the entirety of guilt to self-punishment, thus retracting his view that love functions in the superego as remorse and restitution. This change however, essentially withdraws provision for treating victims of abuse, violence and terror. This paper proposes a paradigm shift that reframes Freud's late instinct theory into a theory of dehumanization by recovering reparative and relational components of guilt...
March 1, 2017: International Journal of Psycho-analysis
https://www.readbyqxmd.com/read/28237843/characterization-of-energy-and-neurotransmitter-metabolism-in-cortical-glutamatergic-neurons-derived-from-human-induced-pluripotent-stem-cells-a-novel-approach-to-study-metabolism-in-human-neurons
#18
Blanca I Aldana, Yu Zhang, Maria Fog Lihme, Lasse K Bak, Jørgen E Nielsen, Bjørn Holst, Poul Hyttel, Kristine K Freude, Helle S Waagepetersen
Alterations in the cellular metabolic machinery of the brain are associated with neurodegenerative disorders such as Alzheimer's disease. Novel human cellular disease models are essential in order to study underlying disease mechanisms. In the present study, we characterized major metabolic pathways in neurons derived from human induced pluripotent stem cells (hiPSC). With this aim, cultures of hiPSC-derived neurons were incubated with [U-(13)C]glucose, [U-(13)C]glutamate or [U-(13)C]glutamine. Isotopic labeling in metabolites was determined using gas chromatography coupled to mass spectrometry, and cellular amino acid content was quantified by high-performance liquid chromatography...
February 24, 2017: Neurochemistry International
https://www.readbyqxmd.com/read/28216144/patient-ipsc-derived-neurons-for-disease-modeling-of-frontotemporal-dementia-with-mutation-in-chmp2b
#19
Yu Zhang, Benjamin Schmid, Nanett K Nikolaisen, Mikkel A Rasmussen, Blanca I Aldana, Mikkel Agger, Kirstine Calloe, Tina C Stummann, Hjalte M Larsen, Troels T Nielsen, Jinrong Huang, Fengping Xu, Xin Liu, Lars Bolund, Morten Meyer, Lasse K Bak, Helle S Waagepetersen, Yonglun Luo, Jørgen E Nielsen, Bjørn Holst, Christian Clausen, Poul Hyttel, Kristine K Freude
The truncated mutant form of the charged multivesicular body protein 2B (CHMP2B) is causative for frontotemporal dementia linked to chromosome 3 (FTD3). CHMP2B is a constituent of the endosomal sorting complex required for transport (ESCRT) and, when mutated, disrupts endosome-to-lysosome trafficking and substrate degradation. To understand the underlying molecular pathology, FTD3 patient induced pluripotent stem cells (iPSCs) were differentiated into forebrain-type cortical neurons. FTD3 neurons exhibited abnormal endosomes, as previously shown in patients...
March 14, 2017: Stem Cell Reports
https://www.readbyqxmd.com/read/28211036/unconscious-phantasy-as-a-structural-principle-and-organizer-of-mental-life-the-evolution-of-a-concept-from-freud-to-klein-and-some-of-her-successors
#20
Heinz Weiss
Starting with Freud's discovery of unconscious phantasy as a means of accessing his patients' internal world, the author discusses the evolution of the concept in the work of Melanie Klein and some of her successors. Whereas Freud sees phantasy as a wish fulfilling imagination, dominated by primary process functioning and kept apart from reality testing, Klein understands phantasies as a structural function and organizer of mental life. From their very beginnings they involve object relations and gradually evolve from primitive body-near experiences to images and symbolic representations...
February 17, 2017: International Journal of Psycho-analysis
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