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https://www.readbyqxmd.com/read/29385605/effect-of-level-of-soluble-fiber-and-n-6-n-3-fatty-acid-ratio-on-performance-of-rabbit-does-and-their-litters
#1
R Delgado, R Abad-Guamán, N Nicodemus, M J Villamide, N Ruiz, R Carabaño, D Menoyo, J García
The aim of this work was to study whether the dietary supplementation with soluble fiber (SF) and the reduction of the n-6/n-3 fatty acid ratio or the combination of both influence the survival, body and milk composition, and reproductive performance of rabbit does during the first four parturitions. Four diets in a 2×2 factorial arrangement were used with two levels of SF (7.8 vs. 13.0, on DM basis; HSF and LSF) and two different n-6/n-3 fatty acid ratio (13.4/1 vs. 3.5/1). Nulliparous does (24/diet) were inseminated 11 d after parturition...
January 29, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29340937/association-between-electronic-medical-record-implementation-of-default-opioid-prescription-quantities-and-prescribing-behavior-in-two-emergency-departments
#2
M Kit Delgado, Frances S Shofer, Mitesh S Patel, Scott Halpern, Christopher Edwards, Zachary F Meisel, Jeanmarie Perrone
No abstract text is available yet for this article.
January 16, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29280066/diagnostic-accuracy-of-11c-methionine-pet-in-detecting-neuropathologically-confirmed-recurrent-brain-tumor-after-radiation-therapy
#3
Annika Kits, Heather Martin, Alejandro Sanchez-Crespo, Anna F Delgado
OBJECTIVE: This study aims to determine the diagnostic test accuracy (DTA) of 11C-methionine (MET) PET in the discrimination between recurrent tumor and radiation-induced injury in neuropathologically confirmed cases. METHODS: A retrospective cohort of 30 patients with previously irradiated intracranial tumors (23 gliomas, 6 metastases, and 1 meningioma) was included. All patients underwent a preoperative MET PET and postoperative neuropathological analysis. Maximum and mean standardized uptake values (SUV) were obtained in the lesion, in the contralateral mirror region, and in the contralateral frontal cortex...
December 26, 2017: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29055613/which-transfers-can-we-avoid-multi-state-analysis-of-factors-associated-with-discharge-home-without-procedure-after-ed-to-ed-transfer-for-traumatic-injury
#4
Laura N Medford-Davis, Daniel N Holena, David Karp, Michael J Kallan, M Kit Delgado
OBJECTIVE: Among injured patients transferred from one emergency department (ED) to another, we determined factors associated with being discharged from the second ED without procedures, or admission or observation. METHODS: We analyzed all patients with injury diagnosis codes transferred between two EDs in the 2011 Healthcare Utilization Project State Emergency Department and State Inpatient Databases for 6 states. Multivariable hierarchical logistic regression evaluated the association between patient (demographics and clinical characteristics) and hospital factors, and discharge from the second ED without coded procedures...
October 11, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28892764/a-european-multicientre-study-on-the-comparison-of-hbv-viral-loads-between-veris-hbv-assay-and-roche-cobas-%C3%A2-taqman-%C3%A2-hbv-test-abbott-realtime-hbv-assay-siemens-versant-hbv-assay-and-qiagen-artus-hbv-rg-kit
#5
Patrick Braun, Rafael Delgado, Monica Drago, Diana Fanti, Hervé Fleury, Jacques Izopet, Alessandra Lombardi, MaAngeles Marcos, Karine Sauné, Siobhan O'Shea, Alfredo Pérez-Rivilla, John Ramble, Pascale Trimoulet, Jordi Vila, Duncan Whittaker, Alain Artus, Daniel Rhodes
BACKGROUND: Hepatitis B viral load testing is essential to treatment and monitoring decisions in patients with chronic Hepatitis B. Beckman Coulter has developed the VERIS HBV Assay (Veris) for use on the fully automated DxN VERIS Molecular Diagnostics System.(1) OBJECTIVES: To evaluate the clinical performance of the Veris HBV Assay at multiple EU laboratories STUDY DESIGN: Method comparison was performed with a total of 344 plasma specimens from HBV infected patients tested with Veris and COBAS(®) TaqMan(®) HBV Test (Cobas), 207 specimens tested with Veris and RealTime HBV Assay (RealTime), 86 specimens tested with Veris and VERSANT(®) HBV Assay (Versant), and 74 specimens tested with Veris and artus(®) HBV RG PCR kit (artus)...
September 8, 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/28661715/patient-characteristics-and-temporal-trends-in-police-transport-of-blunt-trauma-patients-a-multicenter-retrospective-cohort-study
#6
Elinore J Kaufman, Sara F Jacoby, Catherine E Sharoky, Brendan G Carr, M Kit Delgado, Patrick M Reilly, Daniel N Holena
BACKGROUND: Police transport (PT) of penetrating trauma patients has the potential to decrease prehospital times for patients with life-threatening hemorrhage and is part of official policy in Philadelphia, Pennsylvania. We hypothesized that rates of PT of bluntly injured patients have increased over the past decade. METHODS: We used Pennsylvania Trauma Outcomes Study registry data from 2006-15 to identify bluntly injured adult patients transported to all 8 trauma centers in Philadelphia...
November 2017: Prehospital Emergency Care
https://www.readbyqxmd.com/read/28633356/ridesharing-and-motor-vehicle-crashes-in-four-u-s-cities-an-interrupted-time-series-analysis
#7
Christopher N Morrison, Sara F Jacoby, Beidi Dong, M Kit Delgado, Douglas J Wiebe
Uber, the world's largest ridesharing company, has reportedly provided over two billion journeys globally since operations began in 2010; however, the impact on motor vehicle crashes is unclear. Theoretically, ridesharing could reduce alcohol-involved crashes in locations where other modes of transportation are less attractive than driving one's own vehicle while alcohol-affected. We conducted interrupted time series analyses using weekly counts of injury crashes and the proportion that were alcohol-involved in four US cities (Las Vegas, NV; Portland, OR; Reno, NV; San Antonio, TX)...
June 14, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28556460/hla-genotyping-using-the-illumina-hla-trusight-next-generation-sequencing-kits-a-comparison
#8
T Profaizer, E Lázár-Molnár, A Pole, J C Delgado, A Kumánovics
Illumina first introduced their TruSight human leucocyte antigen (HLA) next-generation sequencing (NGS) typing kit in 2015 and subsequently followed up with a new version in 2016. Here we report on our experience comparing the two versions of the Illumina HLA NGS kits.
May 28, 2017: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/28541852/the-pennsylvania-trauma-outcomes-study-risk-adjusted-mortality-model-results-of-a-statewide-benchmarking-program
#9
Douglas J Wiebe, Daniel N Holena, M Kit Delgado, Nathan McWilliams, Juliet Altenburg, Brendan G Carr
Trauma centers need objective feedback on performance to inform quality improvement efforts. The Trauma Quality Improvement Program recently published recommended methodology for case mix adjustment and benchmarking performance. We tested the feasibility of applying this methodology to develop risk-adjusted mortality models for a statewide trauma system. We performed a retrospective cohort study of patients ≥16 years old at Pennsylvania trauma centers from 2011 to 2013 (n = 100,278). Our main outcome measure was observed-to-expected mortality ratios (overall and within blunt, penetrating, multisystem, isolated head, and geriatric subgroups)...
May 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28538625/a-metric-of-our-own-failure-to-rescue-after-trauma
#10
Daniel N Holena, Elinore J Kaufman, M Kit Delgado, Douglas J Wiebe, Brendan G Carr, Jason D Christie, Patrick M Reilly
BACKGROUND: Failure to rescue (FTR) is defined as death after an adverse event. The original metric was derived in elective surgical populations and reclassifies deaths not preceded by recorded adverse events as FTR cases under the assumption these deaths resulted from missed adverse events. This approach lacks face validity in trauma because patients often die without adverse events as a direct result of injury. Another common approach simply excludes deaths without recorded adverse events, but this approach reduces the reliability of the FTR metric...
October 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28431492/anti-drug-antibodies-in-colombian-patients-with-rheumatoid-arthritis-treated-with-enbrel-vs-etanar-preliminary-report
#11
Benjamín Reyes-Beltrán, Gabriela Delgado
The present study was undertaken to detect antibodies against etanercept (ETN) in a group of Colombian patients with rheumatoid arthritis (RA) and being treated with Enbrel(®) vs. Etanar(®). From these patients with RA, clinical and laboratory data were collected and serum taken for anti-drug antibody (ADAb) analysis. Samples from 32 patients (16 who had been treated with Enbrel(®) and 16 with Etanar(®)) were analyzed. Positive sera for ADAb were found in six of the 32 subjects (18.7%); five (31.2%) in the Enbrel(®) group and one (6...
December 2017: Journal of Immunotoxicology
https://www.readbyqxmd.com/read/28423170/us-emergency-department-encounters-for-law-enforcement-associated-injury-2006-2012
#12
Elinore J Kaufman, David N Karp, M Kit Delgado
No abstract text is available yet for this article.
June 1, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28410919/factors-associated-with-hospital-admission-after-an-emergency-department-treat-and-release-visit-for-older-adults-with-injuries
#13
Emily C Earl-Royal, Elinore J Kaufman, Alexandra L Hanlon, Daniel N Holena, Kristin L Rising, M Kit Delgado
INTRODUCTION: Emergency Department (ED) visits for injury often precede hospital admissions in older adults, but risk factors for these admissions are poorly characterized. We sought to determine the incidence and risk factors for hospitalization shortly following discharge home from an ED visit for traumatic injury in older adults. We hypothesized higher risk for admission in those with increased age, discharged home after falls, with increased comorbidity burden, and who live in poor neighborhoods...
September 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28373872/type-i-interferon-gene-response-is-increased-in-early-and-established-rheumatoid-arthritis-and-correlates-with-autoantibody-production
#14
Julio E Castañeda-Delgado, Yadira Bastián-Hernandez, Noe Macias-Segura, David Santiago-Algarra, Jose D Castillo-Ortiz, Ana L Alemán-Navarro, Pedro Martínez-Tejada, Leonor Enciso-Moreno, Yolanda Garcia-De Lira, Diana Olguín-Calderón, Leendert A Trouw, Cesar Ramos-Remus, Jose A Enciso-Moreno
BACKGROUND: Rheumatoid arthritis (RA) is an inflammatory debilitating disease that affects the joints in the early and productive phases of an individual's life. Several cytokines have been linked to the disease pathogenesis and are known to contribute to the inflammatory state characteristic of RA. The participation of type I interferon (IFN) in the pathogenesis of the disease has been already described as well as the identity of the genes that are regulated by this molecule, which are collectively known as the type I IFN signature...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28369814/development-and-validation-of-the-agency-for-healthcare-research-and-quality-measures-of-potentially-preventable-emergency-department-ed-visits-the-ed-prevention-quality%C3%A2-indicators-for-general-health-conditions
#15
Sheryl Davies, Ellen Schultz, Maria Raven, Nancy Ewen Wang, Carol L Stocks, Mucio Kit Delgado, Kathryn M McDonald
OBJECTIVE: To develop and validate rates of potentially preventable emergency department (ED) visits as indicators of community health. DATA SOURCES: Agency for Healthcare Research and Quality, Healthcare Cost and Utilization Project 2008-2010 State Inpatient Databases and State Emergency Department Databases. STUDY DESIGN: Empirical analyses and structured panel reviews. METHODS: Panels of 14-17 clinicians and end users evaluated a set of ED Prevention Quality Indicators (PQIs) using a Modified Delphi process...
October 2017: Health Services Research
https://www.readbyqxmd.com/read/28319158/a-morphological-method-for-ammonia-detection-in-liver
#16
Virginia Gutiérrez-de-Juan, Sergio López de Davalillo, David Fernández-Ramos, Lucía Barbier-Torres, Imanol Zubiete-Franco, Pablo Fernández-Tussy, Jorge Simon, Fernando Lopitz-Otsoa, Javier de Las Heras, Paula Iruzubieta, María Teresa Arias-Loste, Erica Villa, Javier Crespo, Raúl Andrade, M Isabel Lucena, Marta Varela-Rey, Shelly C Lu, José M Mato, Teresa Cardoso Delgado, María-Luz Martínez-Chantar
Hyperammonemia is a metabolic condition characterized by elevated levels of ammonia and a common event in acute liver injury/failure and chronic liver disease. Even though hepatic ammonia levels are potential predictive factors of patient outcome, easy and inexpensive methods aiming at the detection of liver ammonia accumulation in the clinical setting remain unavailable. Thus, herein we have developed a morphological method, based on the utilization of Nessler´s reagent, to accurately and precisely detect the accumulation of ammonia in biological tissue...
2017: PloS One
https://www.readbyqxmd.com/read/28316308/where-we-fail-location-and-timing-of-failure-to-rescue-in-trauma
#17
Jennifer J Chung, Emily C Earl-Royal, M Kit Delgado, Jose L Pascual, Patrick M Reilly, Douglas J Wiebe, Daniel N Holena
Failure to rescue (FTR) is an outcome metric that reflects a center's ability to prevent mortality after a major complication. Identifying the timing and location of FTR events could help target efforts to reduce FTR rates. We sought to characterize the timing and location of FTR occurrences at our center, hypothesizing that FTR rates would be highest early after injury and in settings of lower intensity of care. We used data, prospectively collected from 2009 to 2013, on patients ≥16 years old with minimum Abbreviated Injury Score ≥2 from a single institution...
March 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/27720288/variation-in-the-intensity-of-care-for-patients-with-uncomplicated-renal-colic-presenting-to-u-s-emergency-departments
#18
Joshua W Elder, M Kit Delgado, Benjamin I Chung, Elizabeth A Pirrotta, N Ewen Wang
BACKGROUND: Renal colic results in > 1 million ED visits per year, yet there exists a gap in understanding how the majority of these visits, namely uncomplicated cases, are managed. OBJECTIVE: We assessed patient- and hospital-level variation for emergency department (ED) management of uncomplicated kidney stones. METHODS: We identified ED visits from non-elderly adults (aged 19-79 years) with a primary diagnosis indicating renal stone or colic from the 2011 Nationwide Emergency Department Sample...
December 2016: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27695663/adolescent-cellphone-use-while-driving-an-overview-of-the-literature-and-promising-future-directions-for-prevention
#19
M Kit Delgado, Kathryn J Wanner, Catherine McDonald
Motor vehicle crashes are the leading cause of death in adolescents, and drivers aged 16-19 are the most likely to die in distracted driving crashes. This paper provides an overview of the literature on adolescent cellphone use while driving, focusing on the crash risk, incidence, risk factors for engagement, and the effectiveness of current mitigation strategies. We conclude by discussing promising future approaches to prevent crashes related to cellphone use in adolescents. Handheld manipulation of the phone while driving has been shown to have a 3 to 4-fold increased risk of a near crash or crash, and eye glance duration greater than 2 seconds increases crash risk exponentially...
June 16, 2016: Media and Communication
https://www.readbyqxmd.com/read/27667446/oxidized-ldl-statin-use-morbidity-and-mortality-in-patients-receiving-maintenance-hemodialysis
#20
Sandra Wagner, Mugurel Apetrii, Ziad A Massy, Marcus E Kleber, Graciela E Delgado, Hubert Scharnagel, Winfried März, Marie Metzger, Patrick Rossignol, Alan Jardine, Hallvard Holdaas, Bengt Fellström, Roland Schmieder, Bénédicte Stengel, Faiez Zannad
Statin treatment reduces the risk of cardiovascular mortality in the general population, but it has little or no benefit in hemodialyzed (HD) patients. This may reflect different underlying pathophysiology of cardiovascular disease (CVD) in patients treated with HD, maybe involving the oxidative stress. Our aim was to assess the association of oxidized low-density lipoprotein (oxLDL), determined by Mercodia oxLDL enzyme-linked immunosorbent assay (ELISA) kit, with major adverse cardiac events (MACE) and all-cause mortality in HD patients based on the AURORA trial (rosuvastatin vs placebo), and patients not on HD from the Ludwigshafen Risk and Cardiovascular Health (LURIC) study...
January 2017: Free Radical Research
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