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https://www.readbyqxmd.com/read/27896682/methods-of-power-force-velocity-profiling-during-sprint-running-a-narrative-review
#1
REVIEW
Matt R Cross, Matt Brughelli, Pierre Samozino, Jean-Benoit Morin
The ability of the human body to generate maximal power is linked to a host of performance outcomes and sporting success. Power-force-velocity relationships characterize limits of the neuromuscular system to produce power, and their measurement has been a common topic in research for the past century. Unfortunately, the narrative of the available literature is complex, with development occurring across a variety of methods and technology. This review focuses on the different equipment and methods used to determine mechanical characteristics of maximal exertion human sprinting...
November 28, 2016: Sports Medicine
https://www.readbyqxmd.com/read/27869410/the-effect-of-strength-training-based-on-process-approach-intervention-on-balance-of-children-with-developmental-coordination-disorder
#2
Hasan Kordi, Mehdi Sohrabi, Alireza Saberi Kakhki, Seyed R Attarzadeh Hossini
INTRODUCTION: Balance is one of the main problems of children with developmental coordination disorder (DCD). According to process-oriented approach, besides strength training, neuromuscular adaptations can improve balance. OBJETIVE: To evaluate the effects of strength training on improving static and dynamic balance in DCD children. METHODS AND POPULATION: Children between 7 to 9 years old in Tehran participated in the study through randomized controlled trial design...
December 1, 2016: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/27866730/hereditary-neuropathies-an-update
#3
REVIEW
T Stojkovic
Hereditary neuropathies are the most common inherited neuromuscular diseases. Charcot-Marie-Tooth (CMT) disease represents the most common form with an average prevalence ranging from 1/2500 to 1/1200, depending on the studies. To date and with the advances of the latest generation sequencing, more than 80 genes have been identified. Although the common clinical phenotype comprises a progressive distal muscle weakness and sensory loss, foot deformities and decreased or absent tendon reflexes, clinical and electrophysiological phenotypes exhibit great variability...
November 17, 2016: Revue Neurologique
https://www.readbyqxmd.com/read/27865065/how-do-we-recognize-the-child-with-osas
#4
Koen F Joosten, Helena Larramona, Silvia Miano, Dick Van Waardenburg, Athanasios G Kaditis, Nele Vandenbussche, Refika Ersu
Obstructive sleep-disordered breathing includes a spectrum of clinical entities with variable severity ranging from primary snoring to obstructive sleep apnea syndrome (OSAS). The clinical suspicion for OSAS is most often raised by parental report of specific symptoms and/or abnormalities identified by the physical examination which predispose to upper airway obstruction (e.g., adenotonsillar hypertrophy, obesity, craniofacial abnormalities, neuromuscular disorders). Symptoms and signs of OSAS are classified into those directly related to the intermittent pharyngeal airway obstruction (e...
November 16, 2016: Pediatric Pulmonology
https://www.readbyqxmd.com/read/27856712/rates-of-performance-loss-and-neuromuscular-activity-in-men-and-women-during-cycling-evidence-for-a-common-metabolic-basis-of-muscle-fatigue
#5
Christopher W Sundberg, Sandra K Hunter, Matthew W Bundle
The durations that muscular force and power outputs can be sustained until failure fall predictably on an exponential decline between an individual's 3-s burst maximum to the maximum performance they can sustain aerobically. The exponential time constants describing these rates of performance loss are similar across individuals suggesting that a common metabolically-based mechanism governs muscle fatigue; however, these conclusions come from studies mainly on men. To test whether the same physiological understanding can be applied to women, we compared the performance-duration relationships and neuromuscular activity between 7 men (23...
November 17, 2016: Journal of Applied Physiology
https://www.readbyqxmd.com/read/27854220/-get-the-balance-right-pathological-significance-of-autophagy-perturbation-in-neuromuscular-disorders
#6
Perrine Castets, Stephan Frank, Michael Sinnreich, Markus A Rüegg
Recent research has revealed that autophagy, a major catabolic process in cells, is dysregulated in several neuromuscular diseases and contributes to the muscle wasting caused by non-muscle disorders (e.g. cancer cachexia) or during aging (i.e. sarcopenia). From there, the idea arose to interfere with autophagy or manipulate its regulatory signalling to help restore muscle homeostasis and attenuate disease progression. The major difficulty for the development of therapeutic strategies is to restore a balanced autophagic flux, due to the dynamic nature of autophagy...
May 27, 2016: Journal of Neuromuscular Diseases
https://www.readbyqxmd.com/read/27852738/contributions-of-rapid-neuromuscular-transmission-to-the-fine-control-of-acoustic-parameters-of-birdsong
#7
Caitlin Mencio, Balagurunathan Kuberan, Franz Goller
Neural control of complex vocal behaviors, such as birdsong and speech, requires integration of biomechanical nonlinearities through muscular output. Although control of airflow and tension of vibrating tissues are known functions of vocal muscles, it remains unclear how specific muscle characteristics contribute to specific acoustic parameters. To address this gap, we removed heparan sulfate chains using heparitinases to subtly perturb neuromuscular transmission in the syrinx of adult male zebra finches (Taeniopygia guttata)...
November 16, 2016: Journal of Neurophysiology
https://www.readbyqxmd.com/read/27849388/competition-level-differences-on-the-lower-quarter-y-balance-test-in-baseball-players
#8
Robert J Butler, Garrett Bullock, Todd Arnold, Phillip Plisky, Robin Queen
CONTEXT: Decreased performance in dynamic balance has previously been associated with a history of ulnar collateral ligament injury in baseball players. Previous research on dynamic balance in soccer players has shown that test performance depends on competition level. However, dynamic balance has yet to be examined in baseball players. OBJECTIVE: To understand normative values and determine differences in dynamic balance, as measured by the Lower Quarter Y-Balance Test, across competition levels in baseball players...
November 16, 2016: Journal of Athletic Training
https://www.readbyqxmd.com/read/27836744/dynamic-expression-of-genes-encoding-subunits-of-inward-rectifier-potassium-kir-channels-in-the-yellow-fever-mosquito-aedes-aegypti
#9
Zhongxia Yang, Bethanie-Michelle Statler, Travis L Calkins, Edna Alfaro, Carlos J Esquivel, Matthew F Rouhier, Jerod S Denton, Peter M Piermarini
Inward rectifier potassium (Kir) channels play fundamental roles in neuromuscular, epithelial, and endocrine function in mammals. Recent research in insects suggests that Kir channels play critical roles in the development, immune function, and excretory physiology of fruit flies and/or mosquitoes. Moreover, our group has demonstrated that mosquito Kir channels may serve as valuable targets for the development of novel insecticides. Here we characterize the molecular expression of 5 mRNAs encoding Kir channel subunits in the yellow fever mosquito, Aedes aegypti: Kir1, Kir2A-c, Kir2B, Kir2B', and Kir3...
November 9, 2016: Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology
https://www.readbyqxmd.com/read/27824252/elite-female-basketball-players-body-weight-neuromuscular-training-and-performance-on-the-y-balance-test
#10
Roberto Benis, Matteo Bonato, Antonio La Torre
CONTEXT: Neuromuscular training enhances unconscious motor responses by stimulating both the afferent signals and central mechanisms responsible for dynamic joint control. Dynamic joint-control training is a vital component of injury-prevention programs. OBJECTIVE: To investigate the effects of body-weight neuromuscular training on Y-Balance Test (YBT) performance and postural control in female basketball players. DESIGN: Randomized controlled clinical trial...
September 2016: Journal of Athletic Training
https://www.readbyqxmd.com/read/27814667/assessment-of-relationships-between-joint-motion-quality-and-postural-control-in-patients-with-chronic-ankle-joint-instability
#11
Dawid Bączkowicz, Krzysztof Falkowski, Edyta Majorczyk
Study Design Controlled laboratory study, cross sectional. Background Lateral ankle sprains are among the most common injuries encountered during athletic participation. Following the initial injury there is an alarmingly high risk of re-injury and development of chronic ankle instability (CAI), which is dependent on a combination of factors, including sensorimotor deficits and changes in the biomechanical environment of the ankle joint. Objective To evaluate CAI-related disturbances in arthrokinematic motion quality and postural control and the relationships between them...
November 4, 2016: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/27803816/eeg-source-imaging-guided-by-spatiotemporal-specific-fmri-toward-an-understanding-of-dynamic-cognitive-processes
#12
Thinh Nguyen, Thomas Potter, Trac Nguyen, Christof Karmonik, Robert Grossman, Yingchun Zhang
Understanding the mechanism of neuroplasticity is the first step in treating neuromuscular system impairments with cognitive rehabilitation approaches. To characterize the dynamics of the neural networks and the underlying neuroplasticity of the central motor system, neuroimaging tools with high spatial and temporal accuracy are desirable. EEG and fMRI stand among the most popular noninvasive neuroimaging modalities with complementary features, yet achieving both high spatial and temporal accuracy remains a challenge...
2016: Neural Plasticity
https://www.readbyqxmd.com/read/27791976/foot-and-ankle-kinematics-and-dynamic-electromyography-quantitative-analysis-of-recovery-from-peroneal-neuropathy-in-a-professional-football-player
#13
Nikhil K Prasad, Krista A Coleman Wood, Robert J Spinner, Kenton R Kaufman
The assessment of neuromuscular recovery after peripheral nerve surgery has typically been a subjective physical examination. The purpose of this report was to assess the value of gait analysis in documenting recovery quantitatively. A professional football player underwent gait analysis before and after surgery for a peroneal intraneural ganglion cyst causing a left-sided foot drop. Surface electromyography (SEMG) recording from surface electrodes and motion parameter acquisition from a computerized motion capture system consisting of 10 infrared cameras were performed simultaneously...
2016: Journal of Surgical Orthopaedic Advances
https://www.readbyqxmd.com/read/27790792/als-associated-endoplasmic-reticulum-proteins-in-denervated-skeletal-muscle-implications-for-motor-neuron-disease-pathology
#14
C M Jesse, E Bushuven, P Tripathi, A Chandrasekar, C M Simon, C Drepper, A Yamoah, A Dreser, I Katona, S Johann, C Beyer, S Wagner, M Grond, S Nikolin, J Anink, D Troost, M Sendtner, A Goswami, J Weis
Alpha-motoneurons and muscle fibers are structurally and functionally interdependent. Both cell types particularly rely on endoplasmic reticulum (ER/SR) functions. Mutations of the ER proteins VAPB, SigR1 and HSP27 lead to hereditary motor neuron diseases (MNDs). Here, we determined the expression profile and localization of these ER proteins/chaperons by immunohistochemistry and immunoblotting in biopsy and autopsy muscle tissue of patients with amyotrophic lateral sclerosis (ALS) and other neurogenic muscular atrophies (NMAs) and compared these patterns to mouse models of neurogenic muscular atrophy...
October 28, 2016: Brain Pathology
https://www.readbyqxmd.com/read/27757240/time-dependent-postural-control-adaptations-following-a-neuromuscular-warm-up-in-female-handball-players-a-randomized-controlled-trial
#15
Simon Steib, Peter Zahn, Christine Zu Eulenburg, Klaus Pfeifer, Astrid Zech
BACKGROUND: Female handball athletes are at a particular risk of sustaining lower extremity injuries. The study examines time-dependent adaptations of static and dynamic balance as potential injury risk factors to a specific warm-up program focusing on neuromuscular control. METHODS: Fourty one (24.0 ± 5.9 years) female handball athletes were randomized to an intervention or control group. The intervention group implemented a 15-min specific neuromuscular warm-up program, three times per week for eleven weeks, whereas the control group continued with their regular warm-up...
2016: BMC Sports Science, Medicine and Rehabilitation
https://www.readbyqxmd.com/read/27749289/dose-response-and-cardiopulmonary-side-effects-of-the-novel-neuromuscular-blocking-drug-cw002-in-man
#16
Paul M Heerdt, Hiroshi Sunaga, Joel S Owen, Matthew T Murrell, Jaideep K Malhotra, Deena Godfrey, Michelle Steinkamp, Peter Savard, John J Savarese, Cynthia A Lien
BACKGROUND: CW002 is a benzylisoquinolinium nondepolarizing neuromuscular-blocking drug found to be inactivated by cysteine in preclinical studies. The current study represents a dose escalation clinical trial designed to describe CW002 potency, duration, cardiopulmonary side effects, and histamine release. METHODS: Healthy subjects anesthetized with sevoflurane/nitrous oxide were divided into five groups (n = 6), each receiving a fixed CW002 dose (0.02, 0.04, 0...
December 2016: Anesthesiology
https://www.readbyqxmd.com/read/27746389/beta-band-activity-and-connectivity-in-sensorimotor-and-parietal-cortex-are-important-for-accurate-motor-performance
#17
Jae W Chung, Edward Ofori, Gaurav Misra, Christopher W Hess, David E Vaillancourt
: Accurate motor performance may depend on the scaling of distinct oscillatory activity within the motor cortex and effective neural communication between the motor cortex and other brain areas. Oscillatory activity within the beta-band (13-30Hz) has been suggested to provide distinct functional roles for attention and sensorimotor control, yet it remains unclear how beta-band and other oscillatory activity within and between cortical regions is coordinated to enhance motor performance...
October 14, 2016: NeuroImage
https://www.readbyqxmd.com/read/27740488/an-emg-to-force-processing-approach-for-estimating-in-vivo-hip-muscle-forces-in-normal-human-walking
#18
Ross A Bogey, Lee A Barnes
The force of a single muscle is not directly measurable without invasive methods. Yet invasive techniques are not appropriate for clinical use, thus a non-invasive technique that combined the electromyographic (EMG) signal and a neuromuscular model was developed to determine in vivo active muscle forces at the hip. The EMG-to-force processing (EFP) model included active and passive moment components, and the net EFP moment was compared with the hip moment obtained with standard inverse dynamics techniques ("gold standard")...
October 12, 2016: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/27733504/mechanistic-determinants-of-mbnl-activity
#19
Łukasz J Sznajder, Michał Michalak, Katarzyna Taylor, Piotr Cywoniuk, Michał Kabza, Agnieszka Wojtkowiak-Szlachcic, Magdalena Matłoka, Patryk Konieczny, Krzysztof Sobczak
Muscleblind-like (MBNL) proteins are critical RNA processing factors in development. MBNL activity is disrupted in the neuromuscular disease myotonic dystrophy type 1 (DM1), due to the instability of a non-coding microsatellite in the DMPK gene and the expression of CUG expansion (CUG(exp)) RNAs. Pathogenic interactions between MBNL and CUG(exp) RNA lead to the formation of nuclear complexes termed foci and prevent MBNL function in pre-mRNA processing. The existence of multiple MBNL genes, as well as multiple protein isoforms, raises the question of whether different MBNL proteins possess unique or redundant functions...
October 12, 2016: Nucleic Acids Research
https://www.readbyqxmd.com/read/27711243/cgmp-dependent-protein-kinase-inhibition-extends-the-upper-temperature-limit-of-stimulus-evoked-calcium-responses-in-motoneuronal-boutons-of-drosophila-melanogaster-larvae
#20
Jennifer L Krill, Ken Dawson-Scully
While the mammalian brain functions within a very narrow range of oxygen concentrations and temperatures, the fruit fly, Drosophila melanogaster, has employed strategies to deal with a much wider range of acute environmental stressors. The foraging (for) gene encodes the cGMP-dependent protein kinase (PKG), has been shown to regulate thermotolerance in many stress-adapted species, including Drosophila, and could be a potential therapeutic target in the treatment of hyperthermia in mammals. Whereas previous thermotolerance studies have looked at the effects of PKG variation on Drosophila behavior or excitatory postsynaptic potentials at the neuromuscular junction (NMJ), little is known about PKG effects on presynaptic mechanisms...
2016: PloS One
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