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dynamic neuromuscular

Simon Steib, Peter Zahn, Christine Zu Eulenburg, Klaus Pfeifer, Astrid Zech
BACKGROUND: Female handball athletes are at a particular risk of sustaining lower extremity injuries. The study examines time-dependent adaptations of static and dynamic balance as potential injury risk factors to a specific warm-up program focusing on neuromuscular control. METHODS: Fourty one (24.0 ± 5.9 years) female handball athletes were randomized to an intervention or control group. The intervention group implemented a 15-min specific neuromuscular warm-up program, three times per week for eleven weeks, whereas the control group continued with their regular warm-up...
2016: BMC Sports Science, Medicine and Rehabilitation
Paul M Heerdt, Hiroshi Sunaga, Joel S Owen, Matthew T Murrell, Jaideep K Malhotra, Deena Godfrey, Michelle Steinkamp, Peter Savard, John J Savarese, Cynthia A Lien
BACKGROUND: CW002 is a benzylisoquinolinium nondepolarizing neuromuscular-blocking drug found to be inactivated by cysteine in preclinical studies. The current study represents a dose escalation clinical trial designed to describe CW002 potency, duration, cardiopulmonary side effects, and histamine release. METHODS: Healthy subjects anesthetized with sevoflurane/nitrous oxide were divided into five groups (n = 6), each receiving a fixed CW002 dose (0.02, 0.04, 0...
October 6, 2016: Anesthesiology
Jae W Chung, Edward Ofori, Gaurav Misra, Christopher W Hess, David E Vaillancourt
: Accurate motor performance may depend on the scaling of distinct oscillatory activity within the motor cortex and effective neural communication between the motor cortex and other brain areas. Oscillatory activity within the beta-band (13-30Hz) has been suggested to provide distinct functional roles for attention and sensorimotor control, yet it remains unclear how beta-band and other oscillatory activity within and between cortical regions is coordinated to enhance motor performance...
October 13, 2016: NeuroImage
Ross A Bogey, Lee A Barnes
The force of a single muscle is not directly measurable without invasive methods. Yet invasive techniques are not appropriate for clinical use, thus a non-invasive technique that combined the electromyographic (EMG) signal and a neuromuscular model was developed to determine in vivo active muscle forces at the hip. The EMG-to-force processing (EFP) model included active and passive moment components, and the net EFP moment was compared with the hip moment obtained with standard inverse dynamics techniques ("gold standard")...
October 12, 2016: IEEE Transactions on Neural Systems and Rehabilitation Engineering
Łukasz J Sznajder, Michał Michalak, Katarzyna Taylor, Piotr Cywoniuk, Michał Kabza, Agnieszka Wojtkowiak-Szlachcic, Magdalena Matłoka, Patryk Konieczny, Krzysztof Sobczak
Muscleblind-like (MBNL) proteins are critical RNA processing factors in development. MBNL activity is disrupted in the neuromuscular disease myotonic dystrophy type 1 (DM1), due to the instability of a non-coding microsatellite in the DMPK gene and the expression of CUG expansion (CUG(exp)) RNAs. Pathogenic interactions between MBNL and CUG(exp) RNA lead to the formation of nuclear complexes termed foci and prevent MBNL function in pre-mRNA processing. The existence of multiple MBNL genes, as well as multiple protein isoforms, raises the question of whether different MBNL proteins possess unique or redundant functions...
October 12, 2016: Nucleic Acids Research
Jennifer L Krill, Ken Dawson-Scully
While the mammalian brain functions within a very narrow range of oxygen concentrations and temperatures, the fruit fly, Drosophila melanogaster, has employed strategies to deal with a much wider range of acute environmental stressors. The foraging (for) gene encodes the cGMP-dependent protein kinase (PKG), has been shown to regulate thermotolerance in many stress-adapted species, including Drosophila, and could be a potential therapeutic target in the treatment of hyperthermia in mammals. Whereas previous thermotolerance studies have looked at the effects of PKG variation on Drosophila behavior or excitatory postsynaptic potentials at the neuromuscular junction (NMJ), little is known about PKG effects on presynaptic mechanisms...
2016: PloS One
B O Mainsah, L M Collins, C S Throckmorton
OBJECTIVE: The P300 speller is a popular brain-computer interface (BCI) system that has been investigated as a potential communication alternative for individuals with severe neuromuscular limitations. To achieve acceptable accuracy levels for communication, the system requires repeated data measurements in a given signal condition to enhance the signal-to-noise ratio of elicited brain responses. These elicited brain responses, which are used as control signals, are embedded in noisy electroencephalography (EEG) data...
October 5, 2016: Journal of Neural Engineering
Lars Donath, Ralf Roth, Lukas Zahner, Oliver Faude
BACKGROUND: Adequate static and dynamic balance performance is an important prerequisite during daily and sporting life. Various traditional and innovative balance training concepts have been suggested to improve postural control or neuromuscular fall risk profiles over recent years. Whether slackline training (balancing over narrow nylon ribbons) serves as an appropriate training strategy to improve static and dynamic balance performance is as yet unclear. OBJECTIVE: The aim was to examine the occurrence and magnitude of effects of slackline training compared with an inactive control condition on static and dynamic balance performance parameters in children, adults and seniors...
October 4, 2016: Sports Medicine
Corinne E Wee, Tyler D Ames, Khoi M Le, Tiffany Wang, Laura S Phieffer, Carmen E Quatman
Fragility fractures, or fractures occurring from a low-trauma event, are extremely prevalent among the elderly population worldwide and associated with significant mortality and morbidity. This study evaluated the relationship between FES-I Fear of Falling Survey results, self-reported activity restrictions via the SF-36 survey, and scores recorded by portable, inexpensive clinical assessment tools (CATs) during dynamic functional tasks. Low scores during these tasks may indicate functional deficits that put patients at risk for falls and subsequent fragility fractures...
October 2016: Aging and Disease
Jayden A Clark, Elise J Yeaman, Catherine A Blizzard, Jyoti A Chuckowree, Tracey C Dickson
Amyotrophic lateral sclerosis (ALS) is an aggressive multifactorial disease converging on a common pathology: the degeneration of motor neurons (MNs), their axons and neuromuscular synapses. This vulnerability and dysfunction of MNs highlights the dependency of these large cells on their intracellular machinery. Neuronal microtubules (MTs) are intracellular structures that facilitate a myriad of vital neuronal functions, including activity dependent axonal transport. In ALS, it is becoming increasingly apparent that MTs are likely to be a critical component of this disease...
2016: Frontiers in Cellular Neuroscience
Garrett S Bullock Spt, Nate Brookerson, Amy M Knab, Robert J Butler
Abnormal fundamental movement patterns and upper quarter dynamic balance are proposed mechanisms affecting athletic performance and injury risk. There are few studies investigating functional movement and closed chain upper extremity dynamic stability in swimmers. The purpose of this study was to determine differences in fundamental movement competency and closed chain upper extremity dynamic balance, utilizing the Functional Movement Screen (FMS) and Upper Quarter Y-Balance Test (YBT-UQ), of high school (HS; n=70) and collegiate (COL; n=70) swimmers...
September 16, 2016: Journal of Strength and Conditioning Research
Tjerk Zult, Alli Gokeler, Jos J A M van Raay, Reinoud W Brouwer, Inge Zijdewind, Tibor Hortobágyi
PURPOSE: The function of the anterior cruciate ligament (ACL) patients' non-injured leg is relevant in light of the high incidence of secondary ACL injuries on the contralateral side. However, the non-injured leg's function has only been examined for a selected number of neuromuscular outcomes and often without appropriate control groups. We measured a broad array of neuromuscular functions between legs of ACL patients and compared outcomes to age, sex, and physical activity matched controls...
September 24, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Simon Spencer, Alex Wolf, Alison Rushton
CONTEXT:  Identification of strategies to prevent spinal injury, optimize rehabilitation, and enhance performance is a priority for practitioners. Different exercises produce different effects on neuromuscular performance. Clarity of the purpose of a prescribed exercise is central to a successful outcome. Spinal exercises need to be classified according to the objective of the exercise and planned physical outcome. OBJECTIVE:  To define the modifiable spinal abilities that underpin optimal function during skilled athletic performance, clarify the effect of spinal pain and pathologic conditions, and classify spinal exercises according to the objective of the exercise and intended physical outcomes to inform training and rehabilitation...
September 23, 2016: Journal of Athletic Training
Joshua A Cotter, Steven T Jamison, Sarah A Schloemer, Ajit M W Chaudhari
The purpose of this study was to examine the effect of a neuromuscular dentistry-designed mouthguard (NMDD) on dynamic movement ability. Forty-two competitive athletes (8 females, 21.9 ± 2.9 yrs, 66.8 ± 18.8 kg, 1.68 ± 0.11 m; 34 males, 22.8 ± 4.8 yrs, 77.4 ± 12.7 kg, 1.78 ± 0.08 m) with greater than two years' experience in their designated sport were enrolled in the study. Participants completed the Functional Movement Screen (FMS), modified Star Excursion Balance Test (mSEBT), and a single leg landing (SLL) task...
September 6, 2016: Journal of Strength and Conditioning Research
Taegyu Kim, Eunkuk Kim, Hokyung Choi
OBJECTIVE: To determine whether a neuromuscular rehabilitation program can improve postural stability, and ankle evertor strength, and to examine the temporal changes and persistence of the rehabilitation effects in athletes with chronic ankle instability (CAI). DESIGN: A total of 21 national women's field hockey players participated in this study (CAI, n = 12; control, n = 9). Main outcome measures included isokinetic ankle evertor strength (peak torque, PT; total work, TW) at 30°/s, 60°/s, 90°/s and 120°/s, mediolateral stability index (MSI), and dynamic stability test (TCT)...
August 24, 2016: Journal of Sport Rehabilitation
Lachlan P James, Emma M Beckman, Vincent G Kelly, G Gregory Haff
PURPOSE: To determine whether the maximal strength, impulse and power characteristics of competitive mixed martial arts (MMA) athletes differ according to competition level. METHODS: Twenty-nine male semi-professional and amateur MMA competitors were stratified into either higher-level (HL) or lower-level (LL) performers on the basis of competition grade and success. The one-repetition maximum (1RM) squat was used to assess lower body dynamic strength, while a spectrum of impulse, power, force and velocity variables were evaluated during an incremental load jump squat...
September 15, 2016: International Journal of Sports Physiology and Performance
Seyed Kian Jalaleddini, Ehsan Sobhani Tehrani, Robert Kearney
OBJECTIVE: The purpose of this paper is to present a Structural Decomposition SubSpace (SDSS) method for decomposition of the joint torque to intrinsic, reflexive and voluntary torques and identification of joint dynamic stiffness. METHODS: Firstly, it formulates a novel state-space representation for the joint dynamic stiffness modelled by a parallel-cascade structure with a concise parameter set that provides a direct link between the state-space representation matrices and the parallel-cascade parameters...
August 31, 2016: IEEE Transactions on Bio-medical Engineering
Michiyuki Kawakami, Toshiyuki Fujiwara, Junichi Ushiba, Atsuko Nishimoto, Kaoru Abe, Kaoru Honaga, Atsuko Nishimura, Katsuhiro Mizuno, Mitsuhiko Kodama, Yoshihisa Masakado, Meigen Liu
BACKGROUND: Hybrid assistive neuromuscular dynamic stimulation (HANDS) therapy improved paretic upper extremity motor function in patients with severe to moderate hemiparesis. We hypothesized that brain machine interface (BMI) training would be able to increase paretic finger muscle activity enough to apply HANDS therapy in patients with severe hemiparesis, whose finger extensor was absent. OBJECTIVE: The aim of this study was to assess the efficacy of BMI training followed by HANDS therapy in patients with severe hemiparesis...
September 21, 2016: Restorative Neurology and Neuroscience
M Schumann, P Pelttari, K Doma, L Karavirta, K Häkkinen
This study examined neuromuscular adaptations in recreational endurance runners during 24 weeks of same-session combined endurance and strength training (E+S, n=13) vs. endurance training only (E, n=14). Endurance training was similar in the 2 groups (4-6x/week). Additional maximal and explosive strength training was performed in E+S always after incremental endurance running sessions (35-45 min, 65-85% HRmax). Maximal dynamic leg press strength remained statistically unaltered in E+S but decreased in E at week 24 (-5±5%, p=0...
August 30, 2016: International Journal of Sports Medicine
Hyun Gu Kang, Jonathan B Dingwell
Age-related gait changes may be due to the loss of complexity in the neuromuscular system. This theory is disputed due to inconsistent results from single-scale analyses. Also, behavioral adaptations may confound these changes. We examined whether EMG dynamics during gait is less complex in older adults over a range of timescales using the multiscale entropy method, and whether slower walking attenuates this effect. Surface EMG was measured from the left vastus lateralis (VL), biceps femoris (BF), gastrocnemius (GA), and tibialis anterior (TA) in 17 young and 18 older adults as they walked on a treadmill for 5 minutes at 0...
2016: PloS One
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