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https://www.readbyqxmd.com/read/28329750/optoelectronic-plethysmography-in-clinical-practice-and-research-a-review
#1
Carlo Massaroni, Elena Carraro, Andrea Vianello, Sandra Miccinilli, Michelangelo Morrone, Irisz K Levai, Emiliano Schena, Paola Saccomandi, Silvia Sterzi, John W Dickinson, Samantha Winter, Sergio Silvestri
BACKGROUND: Optoelectronic plethysmography (OEP) is a non-invasive motion capture method to measure chest wall movements and estimate lung volumes. OBJECTIVES: To provide an overview of the clinical findings and research applications of OEP in the assessment of breathing mechanics across populations of healthy and diseased individuals. METHODS: A bibliographic research was performed with the terms "opto-electronic plethysmography," "optoelectronic plethysmography," and "optoelectronic plethysmograph" in 50 digital library and bibliographic search databases resulting in the selection of 170 studies...
March 23, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28320127/measurement-properties-of-a-new-wireless-electrogoniometer-for-quantifying-spasticity-during-the-pendulum-test-in-arsacs-patients
#2
Hung Tien Bui, Cynthia Gagnon, Olivier Audet, Jean Mathieu, Mario Leone
INTRODUCTION: Autosomal recessive spastic ataxia of Charlevoix/Saguenay (ARSACS) is a neuromuscular disorder that induces spasticity in lower limbs. The Wartenberg pendulum test is a classical method of assessing lower limb spasticity based on the dynamics of the pendular leg motion. However, in its original form, this test only provides subjective results and do not allow accurate assessment of spasticity. METHODS: Thirteen ARSACS patients were assessed using a new wireless electrogoniometer to measure spasticity by quantifying oscillation amplitudes and relaxation indices during the Wartenburg pendulum test...
April 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28284391/neuromuscular-manifestations-in-mitochondrial-diseases-in-children
#3
Andrés Nascimento, Carlos Ortez, Cristina Jou, Mar O'Callaghan, Federico Ramos, Àngels Garcia-Cazorla
Mitochondrial diseases exhibit significant clinical and genetic heterogeneity. Mitochondria are highly dynamic organelles that are the major contributor of adenosine triphosphate, through oxidative phosphorylation. These disorders may be developed at any age, with isolated or multiple system involvement, and in any pattern of inheritance. Defects in the mitochondrial respiratory chain impair energy production and almost invariably involve skeletal muscle and peripheral nerves, causing exercise intolerance, cramps, recurrent myoglobinuria, or fixed weakness, which often affects extraocular muscles and results in droopy eyelids (ptosis), progressive external ophthalmoplegia, peripheral ataxia, and peripheral polyneuropathy...
November 2016: Seminars in Pediatric Neurology
https://www.readbyqxmd.com/read/28281681/chemogenetic-stimulation-of-the-hypoglossal-neurons-improves-upper-airway-patency
#4
Thomaz Fleury Curado, Kenneth Fishbein, Huy Pho, Michael Brennick, Olga Dergacheva, Luiz U Sennes, Luu V Pham, Ellen E Ladenheim, Richard Spencer, David Mendelowitz, Alan R Schwartz, Vsevolod Y Polotsky
Obstructive sleep apnea (OSA) is characterized by recurrent upper airway obstruction during sleep. OSA leads to high cardiovascular morbidity and mortality. The pathogenesis of OSA has been linked to a defect in neuromuscular control of the pharynx. There is no effective pharmacotherapy for OSA. The objective of this study was to determine whether upper airway patency can be improved using chemogenetic approach by deploying designer receptors exclusively activated by designer drug (DREADD) in the hypoglossal motorneurons...
March 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28269087/analyzing-the-influence-of-curl-speed-in-fatiguing-biceps-brachii-muscles-using-semg-signals-and-multifractal-detrended-moving-average-algorithm
#5
Kiran Marri, Ramakrishnan Swaminathan
In this work, an attempt has been made to analyze surface electromyography (sEMG) signals of fatiguing biceps brachii muscles at different curl speeds using multifractal detrended moving average (MFDMA) algorithm. For this purpose, signals are recorded from fifty eight healthy subjects while performing curl exercise at their comfortable speed until fatigue. The signals of first and last curls are considered as nonfatigue and fatigue conditions, respectively. Further, the number of curls performed by each subject and the endurance time is used for computing the normalized curl speed...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28253561/the-neurology-of-acutely-failing-respiratory-mechanics
#6
Eelco F M Wijdicks
Forces involved in breathing-which effectively pull in air-are the diaphragmatic, intercostal, spine, and neck muscles. Equally important are the bulbar musculature maintaining the architecture of a patent airway conduit and abdominal wall and internal intercostal muscles providing cough. Acute injury along a neural trajectory from brainstem to muscle will impair the coordinated interaction between these muscle groups. Acutely failing respiratory mechanics can be caused by central and peripheral lesions. In central lesions, the key lesion is in the nucleus ambiguus innervating the dilator muscles of the soft palate, pharynx, and larynx, but abnormal respiratory mechanics rarely coincide with abnormalities of the respiratory pattern generator...
March 2, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/28252410/a-density-based-clustering-approach-to-motor-unit-potential-characterizations-to-support-diagnosis-of-neuromuscular-disorders
#7
Tahereh Kamali, Daniel Stashuk
Electrophysiological muscle classification involves characterization of extracted motor unit potentials (MUPs) followed by the aggregation of these MUP characterizations. Existing techniques consider three classes (i.e., myopathic, neurogenic, and normal) for both MUP characterization and electrophysiological muscle classification. However, diseased induced MUP changes are continuous in nature, which make it difficult to find distinct boundaries between normal, myopathic and neurogenic MUPs. Hence, MUP characterization based on more than three classes is better able to represent the various effects of disease...
February 23, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28243195/part-2-adaptation-of-gait-kinematics-in-unilateral-cerebral-palsy-demonstrates-preserved-independent-neural-control-of-each-limb
#8
Thomas C Bulea, Christopher J Stanley, Diane L Damiano
Motor adaptation, or alteration of neural control in response to a perturbation, is a potential mechanism to facilitate motor learning for rehabilitation. Central nervous system deficits are known to affect locomotor adaptation; yet we demonstrated that similar to adults following stroke, children with unilateral brain injuries can adapt step length in response to unilateral leg weighting. Here, we extend our analysis to explore kinematic strategies underlying step length adaptation and utilize dynamical systems approaches to elucidate how neural control may differ in those with hemiplegic CP across legs and compared to typically developing controls...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28227308/analyzing-the-influence-of-curl-speed-in-fatiguing-biceps-brachii-muscles-using-semg-signals-and-multifractal-detrended-moving-average-algorithm
#9
Kiran Marri, Ramakrishnan Swaminathan, Kiran Marri, Ramakrishnan Swaminathan, Kiuuwncran Marri, Ramakrishnan Swaminathan
In this work, an attempt has been made to analyze surface electromyography (sEMG) signals of fatiguing biceps brachii muscles at different curl speeds using multifractal detrended moving average (MFDMA) algorithm. For this purpose, signals are recorded from fifty eight healthy subjects while performing curl exercise at their comfortable speed until fatigue. The signals of first and last curls are considered as nonfatigue and fatigue conditions, respectively. Further, the number of curls performed by each subject and the endurance time is used for computing the normalized curl speed...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28222578/the-effects-of-prevent-injury-and-enhance-performance-program-in-a-female-soccer-team
#10
Cristina Rodríguez, Soledad Echegoyen, Takeshi Aoyama
BACKGROUND: The purpose of this study is to evaluate the changes of muscle strength in lower limbs and knee valgus alignment using the Prevent Injury and Enhance Performance Program (PEP program) to prevent ACL injuries in female soccer players during an entire season. METHODS: A longitudinal and prospective study was done in twenty female soccer players at the Universidad Nacional Autónoma de México, from a senior team. During 24 weeks the training program was applied three times a week as a part of the team workouts...
February 21, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28208060/rna-toxicity-and-foci-formation-in-microsatellite-expansion-diseases
#11
REVIEW
Nan Zhang, Tetsuo Ashizawa
More than 30 incurable neurological and neuromuscular diseases are caused by simple microsatellite expansions consisted of 3-6 nucleotides. These repeats can occur in non-coding regions and often result in a dominantly inherited disease phenotype that is characteristic of a toxic RNA gain-of-function. The expanded RNA adopts unusual secondary structures, sequesters various RNA binding proteins to form insoluble nuclear foci, and causes cellular defects at a multisystem level. Nuclear foci are dynamic in size, shape and colocalization of RNA binding proteins in different expansion diseases and tissue types...
February 13, 2017: Current Opinion in Genetics & Development
https://www.readbyqxmd.com/read/28207399/motor-unit-potential-jitter-a-new-measure-of-neuromuscular-transmission-instability
#12
Meena AbdelMaseeh, Daniel Stashuk
OBJECTIVE: A new measure of neuromuscular transmission instability, motor unit potential (MUP) jitter, is introduced. MUP jitter can be estimated quickly using motor unit potential trains (MUPTs) extracted from electromyographic (EMG) signals acquired using conventional clinical equipment and needle EMG electrodiagnostic protocols. The primary motivation for developing MUP jitter is to avoid the technical demands associated with estimating jitter using conventional single fibre EMG techniques...
February 9, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28198601/the-effect-of-high-speed-strength-training-with-heavy-and-low-workloads-on-neuromuscular-function-and-maximal-concentric-quadriceps-strength
#13
Ali A Mazani, Mohamed R Hamdinia, Amir H Haghigi, Nosratollah Hedayatpour
BACKGROUND: Dynamic strength training has been widely used to increase the ability of skeletal muscle to produce muscle force. Manipulating resistance training program variables has been commonly used as a tool to optimize maximum strength. This study examined the effects of 12 weeks of high-speed strength training with low and heavy workloads on muscle strength and neuromuscular function of quadriceps muscle. METHODS: Thirty male subjects (age, mean ± SD, 20.6 ± 2...
February 14, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28192831/training-effects-of-the-fifa-11-and-harmoknee-on-several-neuromuscular-parameters-of-physical-performance-measures
#14
Francisco Ayala, Carlos Pomares-Noguera, Francisco Javier Robles-Palazón, Maria Del Pilar García-Vaquero, Ignacio Ruiz-Pérez, Sergio Hernández-Sánchez, Mark De Ste Croix
The main purpose of this study was to analyse the training effects of the FIFA 11+ and Harmoknee on several parameters of physical performance measures in youth amateur football players. 41 adolescent players were randomised within each team into 2 groups (team 1: control vs. FIFA 11+; team 2: control vs. Harmoknee). The FIFA 11+ and Harmoknee groups performed the program 3 times a week for 4 weeks; the control groups completed their usual warm-up routines. 13 physical performance measures (joint range of motion, dynamic postural control, single legged hop limb symmetry, sprint time, jumping height and agility) were assessed...
February 13, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/28191352/hybrid-assistive-neuromuscular-dynamic-stimulation-therapy-a-new-strategy-for-improving-upper-extremity-function-in-patients-with-hemiparesis-following-stroke
#15
REVIEW
Toshiyuki Fujiwara, Michiyuki Kawakami, Kaoru Honaga, Michi Tochikura, Kaoru Abe
Hybrid Assistive Neuromuscular Dynamic Stimulation (HANDS) therapy is one of the neurorehabilitation therapeutic approaches that facilitates the use of the paretic upper extremity (UE) in daily life by combining closed-loop electromyography- (EMG-) controlled neuromuscular electrical stimulation (NMES) with a wrist-hand splint. This closed-loop EMG-controlled NMES can change its stimulation intensity in direct proportion to the changes in voluntary generated EMG amplitudes recorded with surface electrodes placed on the target muscle...
2017: Neural Plasticity
https://www.readbyqxmd.com/read/28173788/real-time-optimized-biofeedback-utilizing-sport-techniques-robust-a-study-protocol-for-a-randomized-controlled-trial
#16
Jeffrey B Taylor, Anh-Dung Nguyen, Mark V Paterno, Bin Huang, Kevin R Ford
BACKGROUND: Anterior cruciate ligament (ACL) injuries in female athletes lead to a variety of short- and long-term physical, financial, and psychosocial ramifications. While dedicated injury prevention training programs have shown promise, ACL injury rates remain high as implementation has not become widespread. Conventional prevention programs use a combination of resistance, plyometric, balance and agility training to improve high-risk biomechanics and reduce the risk of injury. While many of these programs focus on reducing knee abduction load and posture during dynamic activity, targeting hip extensor strength and utilization may be more efficacious, as it is theorized to be an underlying mechanism of injury in adolescent female athletes...
February 7, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28154888/permanent-knee-sensorimotor-system-changes-following-acl-injury-and-surgery
#17
John Nyland, Collin Gamble, Tiffany Franklin, David N M Caborn
The cruciate ligaments are components of the knee capsuloligamentous system providing vital neurosensory and biomechanical function. Since most historical primary ACL repair attempts were unsuccessful, reconstruction has become the preferred surgery. However, an increased understanding of the efficacy of lesion-site scaffolding, innovative suturing methods and materials, and evolving use of biological healing mediators such as platelet-rich plasma and stem cells has prompted reconsideration of what was once believed to be impossible...
February 2, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28144405/the-impact-of-kitesurfing-on-the-dynamic-equilibrium
#18
Rafael Leonardo Ferreira da Luz, Fernando Alves da Silva, Marcelo Coertjens
BACKGROUND: The kitesurfing athletes endure unexpected conditions in terms of the function of irregularities in the surface of the water that requires a correct proprioceptive response in order to maintain equilibrium and execute the required movements while maintaining contact with the board and the water. OBJECTIVES: The objective of this work was to use the star excursion balance test to compare the dynamic equilibrium of athletes who engage in kitesurfing activities with non-athletic subjects...
December 2016: Asian Journal of Sports Medicine
https://www.readbyqxmd.com/read/28141512/sonomyography-analysis-on-thickness-of-skeletal-muscle-during-dynamic-contraction-induced-by-neuromuscular-electrical-stimulation-a-pilot-study
#19
Shuang Qiu, Jing Feng, Jiapeng Xu, Rui Xu, Xin Zhao, Peng Zhou, Hongzhi Qi, Lixin Zhang, Dong Ming
Neuromuscular electrical stimulation (NMES) that stimulates skeletal muscles to induce contractions has been widely applied to restore functions of paralyzed muscles. However, the architectural changes of stimulated muscles induced by NMES are still not well understood. The present study applies sonomyography (SMG) to evaluate muscle architecture under NMES-induced and voluntary movements. The quadriceps muscles of seven healthy subjects were tested for eight cycles during an extension exercise of the knee joint with/without NMES, and SMG and the knee joint angle were recorded during the process of knee extension...
January 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28130447/pseudouridine-modification-inhibits-muscleblind-like-1-mbnl1-binding-to-ccug-repeats-and-minimally-structured-rna-through-reduced-rna-flexibility
#20
Elaine deLorimier, Melissa N Hinman, Jeremy Copperman, Kausiki Datta, Marina Guenza, J Andrew Berglund
Myotonic dystrophy type 2 is a genetic neuromuscular disease caused by the expression of expanded CCUG repeat RNAs from the non-coding region of the CCHC-type zinc finger nucleic acid-binding protein (CNBP) gene. These CCUG repeats bind and sequester a family of RNA-binding proteins known as Muscleblind-like 1, 2, and 3 (MBNL1, MBNL2, and MBNL3), and sequestration plays a significant role in pathogenicity. MBNL proteins are alternative splicing regulators that bind to the consensus RNA sequence YGCY (Y = pyrimidine)...
March 10, 2017: Journal of Biological Chemistry
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