keyword
MENU ▼
Read by QxMD icon Read
search

hiporfin

keyword
https://www.readbyqxmd.com/read/25619546/hiporfin-mediated-photodynamic-therapy-in-preclinical-treatment-of-osteosarcoma
#1
Mengxiong Sun, Chenghao Zhou, Hui Zeng, Nahum Puebla-Osorio, Elisabetta Damiani, Jian Chen, Hongsheng Wang, Guodong Li, Fei Yin, Liancheng Shan, Dongqing Zuo, Yuxin Liao, Zhuoying Wang, Longpo Zheng, Yingqi Hua, Zhengdong Cai
This study was carried out to investigate the anti-tumor effect and mechanism of hiporfin-mediated photodynamic therapy (hiporfin-PDT) in osteosarcoma. We found that hiporfin accumulated mainly in the cytoplasm of osteosarcoma cells in a time and concentration-dependent manner. Hiporfin-PDT inhibited the proliferation, induced apoptosis and produced cell cycle arrest at G2M in osteosarcoma cell lines. Hiporfin-PDT increased the expression of cleaved-caspase-3, cleaved PARP-1, Bax and RIP1 while it decreased the expression of Bcl-2; in addition, low concentration of hiporfin increased LC3 conversion...
May 2015: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/22369734/fluorescence-examination-and-photodynamic-therapy-of-facial-squamous-cell-carcinoma-a-case-report
#2
Xiaona Zhang, Jinzhang Chen, Yuling Luo, Lanying Zhang, Rongcheng Luo, Libo Li
BACKGROUND AND OBJECTIVE: To evaluate the usefulness and feasibility of fluorescence examination and photodynamic therapy (PDT) for facial squamous cell carcinoma. METHODS: A 68-year-old male patient underwent 3 courses of PDT. The first treatment was carried out using topically applied 5-aminolevulinic acid (ALA) to the affected area (5.0 cm × 2.5 cm) 3h before light irradiation. ALA/PpIX-mediated fluorescence was used to visualize the lesion and its margin. The lesion was illuminated with a 630 nm laser at 120 J/cm²...
March 2012: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/19356672/an-update-on-the-regulatory-status-of-pdt-photosensitizers-in-china
#3
Zheng Huang
Numerous photosensitizers have been developed and evaluated in China. HiPorfin, a hematoporphyrin derivative (HpD) received the first regulatory approval in the early 2000s. Aila, a topical formulation containing predrug 5-aminolevulinic acid, received the regulatory approval in 2007. Recently, new drug applications have been filed for several hematoporphyrin derivatives and a zinc phthalocyanine (ZnPc) derivative. This short report will summarize the current regulatory status of Chinese photosensitizers developed for photodynamic therapy (PDT)...
December 2008: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/19242772/treatment-of-perianal-paget-s-disease-using-photodynamic-therapy-with-assistance-of-fluorescence-examination-case-report
#4
Libo Li, Yongjian Deng, Lanying Zhang, Wangjun Liao, Rongcheng Luo, Zheng Huang
Our aim was to determine the usefulness of fluorescence examination and photodynamic therapy (PDT) for the management of perianal extramammary Paget's disease. A 75-year-old woman underwent two courses of PDT. The first treatment was carried out with topically applied 5-aminolevulinic acid (ALA) to the affected area (2.5 x 2.5 cm(2)) 3 h before light treatment. We used ALA/protoporphyrin IX (PpIX)-mediated fluorescence to visualize the lesion and its margins. The lesion was treated with a 630 nm laser at 120 J/cm(2)...
November 2009: Lasers in Medical Science
1
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"