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JOURNAL ARTICLE
Che Harris, Yingfei Tang, Eliana Birnbaum, Christine Cherian, Dinesh Mendhe, Michelle H Chen
Compared with other health disciplines, there is a stagnation in technological innovation in the field of clinical neuropsychology. Traditional paper-and-pencil tests have a number of shortcomings, such as low-frequency data collection and limitations in ecological validity. While computerized cognitive assessment may help overcome some of these issues, current computerized paradigms do not address the majority of these limitations. In this paper, we review recent literature on the applications of novel digital health approaches, including ecological momentary assessment, smartphone-based assessment and sensors, wearable devices, passive driving sensors, smart homes, voice biomarkers, and electronic health record mining, in neurological populations...
March 22, 2024: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
#22
JOURNAL ARTICLE
Michael B Lilly, Chunli Wu, Yu Ke, Wen-Pin Chen, Adam C Soloff, Kent Armeson, Noriko N Yokoyama, Xiaotian Li, Liankun Song, Ying Yuan, Christine E McLaren, Xiaolin Zi
PURPOSE: Our preclinical studies showed that lycopene enhanced the anti-prostate cancer efficacy of docetaxel in animal models. A phase I trial (NCT0149519) was conducted to identify an optimum dose of synthetic lycopene in combination with docetaxel (and androgen blockade [androgen deprivation therapy, ADT]), and to evaluate its effect on the safety and pharmacokinetics of docetaxel in men with metastatic prostate cancer. METHODS: Subjects were treated with 21-day cycles of 75 mg/m2 docetaxel (and ADT), plus lycopene at 30, 90 or 150 mg/day...
March 2024: Clinical and Translational Medicine
#23
Christine E Brown, Jonathan C Hibbard, Darya Alizadeh, M Suzette Blanchard, Heini M Natri, Dongrui Wang, Julie R Ostberg, Brenda Aguilar, Jamie R Wagner, Jinny A Paul, Renate Starr, Robyn A Wong, Wuyang Chen, Noah Shulkin, Maryam Aftabizadeh, Aleksandr Filippov, Ammar Chaudhry, Julie A Ressler, Julie Kilpatrick, Paige Myers-McNamara, Mike Chen, Leo D Wang, Russell C Rockne, Joseph Georges, Jana Portnow, Michael E Barish, Massimo D'Apuzzo, Nicholas E Banovich, Stephen J Forman, Behnam Badie
No abstract text is available yet for this article.
March 21, 2024: Nature Medicine
#24
JOURNAL ARTICLE
Laura B Murdaugh, Cristina Miliano, Irene Chen, Christine L Faunce, Luis A Natividad, Ann M Gregus, Matthew W Buczynski
Nicotine use is a leading cause of preventable deaths worldwide, and most of those who attempt to quit will relapse. While electronic cigarettes and other electronic nicotine delivery systems (ENDS) were presented as a safer alternative to traditional cigarettes and promoted as devices to help traditional tobacco smokers reduce or quit smoking, they have instead contributed to increasing nicotine use among youths. Despite this, ENDS also represent a useful tool to create novel preclinical animal models of nicotine exposure that more accurately represent human nicotine use...
March 19, 2024: Scientific Reports
#25
JOURNAL ARTICLE
Jia Ying Tang, Poh Hoon June Teng, Christine Yuanxin Chen, Keng Teng Tan, Wendy Ang, Sabrina Lau, Alexis Guat Cheng Ang, Kay Khine Kyaw, Xin Yong Tay, Wan Min Stephanie Lim, Wrenzie Del Valle Espeleta, Huimin Lin, Yew Yoong Ding, Penny Lun
BACKGROUND: Potentially inappropriate prescribing is common among older adults with multimorbidity due to various reasons, from concurrent application of multiple single-disease clinical guidelines to fragmentation of care. Interventions such as medication review have been implemented worldwide to reduce inappropriate prescribing for older adults. However, the implementability of such interventions are underexplored in the outpatient clinics in Singapore's public hospitals. Hence, the Pro-M study aims to assess the feasibility of implementing a physician-pharmacist collaborative care intervention in geriatric medicine outpatient clinics to facilitate appropriate prescribing for older adults in Singapore...
March 18, 2024: Archives of Public Health, Archives Belges de Santé Publique
#26
JOURNAL ARTICLE
A Cole Burton, Christopher Beirne, Kaitlyn M Gaynor, Catherine Sun, Alys Granados, Maximilian L Allen, Jesse M Alston, Guilherme C Alvarenga, Francisco Samuel Álvarez Calderón, Zachary Amir, Christine Anhalt-Depies, Cara Appel, Stephanny Arroyo-Arce, Guy Balme, Avi Bar-Massada, Daniele Barcelos, Evan Barr, Erika L Barthelmess, Carolina Baruzzi, Sayantani M Basak, Natalie Beenaerts, Jonathan Belmaker, Olgirda Belova, Branko Bezarević, Tori Bird, Daniel A Bogan, Neda Bogdanović, Andy Boyce, Mark Boyce, LaRoy Brandt, Jedediah F Brodie, Jarred Brooke, Jakub W Bubnicki, Francesca Cagnacci, Benjamin Scott Carr, João Carvalho, Jim Casaer, Rok Černe, Ron Chen, Emily Chow, Marcin Churski, Connor Cincotta, Duško Ćirović, T D Coates, Justin Compton, Courtney Coon, Michael V Cove, Anthony P Crupi, Simone Dal Farra, Andrea K Darracq, Miranda Davis, Kimberly Dawe, Valerie De Waele, Esther Descalzo, Tom A Diserens, Jakub Drimaj, Martin Duľa, Susan Ellis-Felege, Caroline Ellison, Alper Ertürk, Jean Fantle-Lepczyk, Jorie Favreau, Mitch Fennell, Pablo Ferreras, Francesco Ferretti, Christian Fiderer, Laura Finnegan, Jason T Fisher, M Caitlin Fisher-Reid, Elizabeth A Flaherty, Urša Fležar, Jiří Flousek, Jennifer M Foca, Adam Ford, Barbara Franzetti, Sandra Frey, Sarah Fritts, Šárka Frýbová, Brett Furnas, Brian Gerber, Hayley M Geyle, Diego G Giménez, Anthony J Giordano, Tomislav Gomercic, Matthew E Gompper, Diogo Maia Gräbin, Morgan Gray, Austin Green, Robert Hagen, Robert Bob Hagen, Steven Hammerich, Catharine Hanekom, Christopher Hansen, Steven Hasstedt, Mark Hebblewhite, Marco Heurich, Tim R Hofmeester, Tru Hubbard, David Jachowski, Patrick A Jansen, Kodi Jo Jaspers, Alex Jensen, Mark Jordan, Mariane C Kaizer, Marcella J Kelly, Michel T Kohl, Stephanie Kramer-Schadt, Miha Krofel, Andrea Krug, Kellie M Kuhn, Dries P J Kuijper, Erin K Kuprewicz, Josip Kusak, Miroslav Kutal, Diana J R Lafferty, Summer LaRose, Marcus Lashley, Richard Lathrop, Thomas E Lee, Christopher Lepczyk, Damon B Lesmeister, Alain Licoppe, Marco Linnell, Jan Loch, Robert Long, Robert C Lonsinger, Julie Louvrier, Matthew Scott Luskin, Paula MacKay, Sean Maher, Benoît Manet, Gareth K H Mann, Andrew J Marshall, David Mason, Zara McDonald, Tracy McKay, William J McShea, Matt Mechler, Claude Miaud, Joshua J Millspaugh, Claudio M Monteza-Moreno, Dario Moreira-Arce, Kayleigh Mullen, Christopher Nagy, Robin Naidoo, Itai Namir, Carrie Nelson, Brian O'Neill, M Teague O'Mara, Valentina Oberosler, Christian Osorio, Federico Ossi, Pablo Palencia, Kimberly Pearson, Luca Pedrotti, Charles E Pekins, Mary Pendergast, Fernando F Pinho, Radim Plhal, Xochilt Pocasangre-Orellana, Melissa Price, Michael Procko, Mike D Proctor, Emiliano Esterci Ramalho, Nathan Ranc, Slaven Reljic, Katie Remine, Michael Rentz, Ronald Revord, Rafael Reyna-Hurtado, Derek Risch, Euan G Ritchie, Andrea Romero, Christopher Rota, Francesco Rovero, Helen Rowe, Christian Rutz, Marco Salvatori, Derek Sandow, Christopher M Schalk, Jenna Scherger, Jan Schipper, Daniel G Scognamillo, Çağan H Şekercioğlu, Paola Semenzato, Jennifer Sevin, Hila Shamon, Catherine Shier, Eduardo A Silva-Rodríguez, Magda Sindicic, Lucy K Smyth, Anil Soyumert, Tiffany Sprague, Colleen Cassady St Clair, Jennifer Stenglein, Philip A Stephens, Kinga Magdalena Stępniak, Michael Stevens, Cassondra Stevenson, Bálint Ternyik, Ian Thomson, Rita T Torres, Joan Tremblay, Tomas Urrutia, Jean-Pierre Vacher, Darcy Visscher, Stephen L Webb, Julian Weber, Katherine C B Weiss, Laura S Whipple, Christopher A Whittier, Jesse Whittington, Izabela Wierzbowska, Martin Wikelski, Jacque Williamson, Christopher C Wilmers, Todd Windle, Heiko U Wittmer, Yuri Zharikov, Adam Zorn, Roland Kays
Wildlife must adapt to human presence to survive in the Anthropocene, so it is critical to understand species responses to humans in different contexts. We used camera trapping as a lens to view mammal responses to changes in human activity during the COVID-19 pandemic. Across 163 species sampled in 102 projects around the world, changes in the amount and timing of animal activity varied widely. Under higher human activity, mammals were less active in undeveloped areas but unexpectedly more active in developed areas while exhibiting greater nocturnality...
March 18, 2024: Nature Ecology & Evolution
#27
JOURNAL ARTICLE
Carlo Pierpaoli, Amritha Nayak, Rakibul Hafiz, M Okan Irfanoglu, Gang Chen, Paul Taylor, Mark Hallett, Michael Hoa, Dzung Pham, Yi-Yu Chou, Anita D Moses, André J van der Merwe, Sara M Lippa, Carmen C Brewer, Chris K Zalewski, Cris Zampieri, L Christine Turtzo, Pashtun Shahim, Leighton Chan, Brian Moore, Lauren Stamps, Spencer Flynn, Julia Fontana, Swathi Tata, Jessica Lo, Mirella A Fernandez, Annie Lori-Joseph, Jesse Matsubara, Julie Goldberg, Thuy-Tien D Nguyen, Noa Sasson, Justine Lely, Bryan Smith, Kelly A King, Jennifer Chisholm, Julie Christensen, M Teresa Magone, Chantal Cousineau-Krieger, Louis M French, Simge Yonter, Sanaz Attaripour, Chen Lai
IMPORTANCE: US government personnel stationed internationally have reported anomalous health incidents (AHIs), with some individuals experiencing persistent debilitating symptoms. OBJECTIVE: To assess the potential presence of magnetic resonance imaging (MRI)-detectable brain lesions in participants with AHIs, with respect to a well-matched control group. DESIGN, SETTING, AND PARTICIPANTS: This exploratory study was conducted at the National Institutes of Health (NIH) Clinical Center and the NIH MRI Research Facility between June 2018 and November 2022...
March 18, 2024: JAMA
#28
JOURNAL ARTICLE
Leighton Chan, Mark Hallett, Chris K Zalewski, Carmen C Brewer, Cris Zampieri, Michael Hoa, Sara M Lippa, Edmond Fitzgibbon, Louis M French, Anita D Moses, André J van der Merwe, Carlo Pierpaoli, L Christine Turtzo, Simge Yonter, Pashtun Shahim, Brian Moore, Lauren Stamps, Spencer Flynn, Julia Fontana, Swathi Tata, Jessica Lo, Mirella A Fernandez, Annie-Lori Joseph, Jesse Matsubara, Julie Goldberg, Thuy-Tien D Nguyen, Noa Sasson, Justine Lely, Bryan Smith, Kelly A King, Jennifer Chisholm, Julie Christensen, M Teresa Magone, Chantal Cousineau-Krieger, Rakibul Hafiz, Amritha Nayak, Okan Irfanoglu, Sanaz Attaripour, Chen Lai, Wendy B Smith
IMPORTANCE: Since 2015, US government and related personnel have reported dizziness, pain, visual problems, and cognitive dysfunction after experiencing intrusive sounds and head pressure. The US government has labeled these anomalous health incidents (AHIs). OBJECTIVE: To assess whether participants with AHIs differ significantly from US government control participants with respect to clinical, research, and biomarker assessments. DESIGN, SETTING, AND PARTICIPANTS: Exploratory study conducted between June 2018 and July 2022 at the National Institutes of Health Clinical Center, involving 86 US government staff and family members with AHIs from Cuba, Austria, China, and other locations as well as 30 US government control participants...
March 18, 2024: JAMA
#29
JOURNAL ARTICLE
Mary-Luyza Avramescu, Katherine Casey, Christine Levesque, Jian Chen, Clare Wiseman, Suzanne Beauchemin
Resuspension of road dust is a major source of airborne particulate matter (PM) in urban environments. Inhalation of ultrafine particles (UFP; < 0.1 μm) represents a health concern due to their ability to reach the alveoli and be translocated into the blood stream. It is therefore important to characterize chemical properties of UFPs associated with vehicle emissions. We investigated the capability of Single-Particle ICP-MS (SP-ICP-MS) to quantify key metal(loid)s in nanoparticles (NPs; < 0...
March 13, 2024: Science of the Total Environment
#30
JOURNAL ARTICLE
Ryan D Imhoff, Rishi Patel, Muhammad Hassan Safdar, Hannah B L Jones, Adan Pinto-Fernandez, Iolanda Vendrell, Hao Chen, Christine S Muli, Aaron D Krabill, Benedikt M Kessler, Michael K Wendt, Chittaranjan Das, Daniel P Flaherty
Dysregulation of the ubiquitin-proteasome systems is a hallmark of various disease states including neurodegenerative diseases and cancer. Ubiquitin C-terminal hydrolase L1 (UCHL1), a deubiquitinating enzyme, is expressed primarily in the central nervous system under normal physiological conditions, however, is considered an oncogene in various cancers, including melanoma, lung, breast, and lymphoma. Thus, UCHL1 inhibitors could serve as a viable treatment strategy against these aggressive cancers. Herein, we describe a covalent fragment screen that identified the chloroacetohydrazide scaffold as a covalent UCHL1 inhibitor...
March 15, 2024: Journal of Medicinal Chemistry
#31
JOURNAL ARTICLE
Laurie-Anne Boivin-Proulx, Fabrice Ieroncig, Simon-Pierre Demers, Anna Nozza, Marwa Soltani, Ismahane Ghersi, Louis Verreault-Julien, Yahya Alansari, Charles Massie, Philippe Simard, Lorena Rosca, Jean-Simon Lalancette, Gabriel Massicotte, Annabel Chen-Tournoux, Benoit Daneault, Jean-Michel Paradis, Jean G Diodati, Nicolas Pranno, Marc Jolicoeur, Brian J Potter, Guillaume Marquis-Gravel, Christine Pacheco
BACKGROUND: In patients with anterior ST-elevation myocardial infarction (STEMI) and new-onset antero-apical wall motion abnormalities (WMAs), whether the rate of prophylaxis against left ventricular thrombus and outcomes differ between men and women is unknown. METHODS: A multicentre retrospective cohort study of patients with STEMI and new-onset antero-apical WMAs treated with primary percutaneous coronary intervention was conducted. Patients with an established indication of oral anticoagulation (OAC) were excluded...
February 2024: CJC open
#32
JOURNAL ARTICLE
Christine Bowman, Michael Dolton, Fang Ma, Sravanthi Cheeti, Denison Kuruvilla, Rucha Sane, Nastya Kassir, Yuan Chen
Pralsetinib, a potent and selective inhibitor of oncogenic RET fusion and RET mutant proteins, is a substrate of the drug metabolizing enzyme CYP3A4 and a substrate of the efflux transporter P-gp based on in vitro data. Therefore, its pharmacokinetics (PKs) may be affected by co-administration of potent CYP3A4 inhibitors and inducers, P-gp inhibitors, and combined CYP3A4 and P-gp inhibitors. With the frequent overlap between CYP3A4 and P-gp substrates/inhibitors, pralsetinib is a challenging and representative example of the need to more quantitatively characterize transporter-enzyme interplay...
March 13, 2024: CPT: Pharmacometrics & Systems Pharmacology
#33
JOURNAL ARTICLE
Régis Peffault de Latour, Alexander Röth, Austin G Kulasekararaj, Bing Han, Phillip Scheinberg, Jaroslaw P Maciejewski, Yasutaka Ueda, Carlos M de Castro, Eros Di Bona, Rong Fu, Li Zhang, Morag Griffin, Saskia M C Langemeijer, Jens Panse, Hubert Schrezenmeier, Wilma Barcellini, Vitor A Q Mauad, Philippe Schafhausen, Suzanne Tavitian, Eloise Beggiato, Lee Ping Chew, Anna Gaya, Wei-Han Huang, Jun Ho Jang, Toshio Kitawaki, Abdullah Kutlar, Rosario Notaro, Vinod Pullarkat, Jörg Schubert, Louis Terriou, Michihiro Uchiyama, Lily Wong Lee Lee, Eng-Soo Yap, Flore Sicre de Fontbrune, Luana Marano, Ferras Alashkar, Shreyans Gandhi, Roochi Trikha, Chen Yang, Hui Liu, Richard J Kelly, Britta Höchsmann, Cécile Kerloeguen, Partha Banerjee, Rafael Levitch, Rakesh Kumar, Zhixin Wang, Christine Thorburn, Samopriyo Maitra, Shujie Li, Aurelie Verles, Marion Dahlke, Antonio M Risitano
BACKGROUND: Persistent hemolytic anemia and a lack of oral treatments are challenges for patients with paroxysmal nocturnal hemoglobinuria who have received anti-C5 therapy or have not received complement inhibitors. Iptacopan, a first-in-class oral factor B inhibitor, has been shown to improve hemoglobin levels in these patients. METHODS: In two phase 3 trials, we assessed iptacopan monotherapy over a 24-week period in patients with hemoglobin levels of less than 10 g per deciliter...
March 14, 2024: New England Journal of Medicine
#34
JOURNAL ARTICLE
Ali Alajmi, Ghassan Niaz, Christine Chen, Kachiu Lee
BACKGROUND: Improving the appearance of lentigines on the hands is a key component to hand rejuvenation. Soft tissue fillers revolumize hands, but do not address pigmentary changes. OBJECTIVE: This study investigated the effiacy of a 15% trichloroacetic acid (TCA) + 3% glycolic acid (GA) combination peel in improvement of appearance of hand lentigines. METHODS: A prospective evaluator-blinded, split-hand study was performed using a 15% TCA + 3% GA peel to treat patients with hand lentigines...
March 8, 2024: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
#35
JOURNAL ARTICLE
Christine E Brown, Jonathan C Hibbard, Darya Alizadeh, M Suzette Blanchard, Heini M Natri, Dongrui Wang, Julie R Ostberg, Brenda Aguilar, Jamie R Wagner, Jinny A Paul, Renate Starr, Robyn A Wong, Wuyang Chen, Noah Shulkin, Maryam Aftabizadeh, Aleksandr Filippov, Ammar Chaudhry, Julie A Ressler, Julie Kilpatrick, Paige Myers-McNamara, Mike Chen, Leo D Wang, Russell C Rockne, Joseph Georges, Jana Portnow, Michael E Barish, Massimo D'Apuzzo, Nicholas E Banovich, Stephen J Forman, Behnam Badie
Chimeric antigen receptor T cell (CAR-T) therapy is an emerging strategy to improve treatment outcomes for recurrent high-grade glioma, a cancer that responds poorly to current therapies. Here we report a completed phase I trial evaluating IL-13Rα2-targeted CAR-T cells in 65 patients with recurrent high-grade glioma, the majority being recurrent glioblastoma (rGBM). Primary objectives were safety and feasibility, maximum tolerated dose/maximum feasible dose and a recommended phase 2 dose plan. Secondary objectives included overall survival, disease response, cytokine dynamics and tumor immune contexture biomarkers...
March 7, 2024: Nature Medicine
#36
JOURNAL ARTICLE
Jeremy P Harris, Jino Park, Eric Ku, Steven Seyedin, Russell Stitzlein, Amanda Goldin, Wen-Pin Chen, Christine McLaren, Allen M Chen, Warren Chow
OBJECTIVES: Immunotherapy with immune checkpoint inhibitors has shown only limited success in the management of metastatic soft tissue sarcoma. Overall response rates (ORR) with single agent pembrolizumab were 18% and median PFS was 18 weeks on the clinical trial SARC028. One strategy to improve the responses to immunotherapy is with stereotactic body radiation therapy (SBRT), which can enhance the antitumor CD8 T cell response through the release of tumor-specific antigens, potentially priming a more diverse class of T cell receptors...
2024: Cancer Control: Journal of the Moffitt Cancer Center
#37
JOURNAL ARTICLE
Yinting Chen, Christine Lafleur, Ryan J Smith, Diljot Kaur, Brian T Driscoll, Jacqueline C Bede
Many plant species, particularly legumes, protect themselves with saponins. Previously, a correlation was observed between levels of oleanolic acid-derived saponins, such as hederagenin-derived compounds, in the legume Medicago truncatula and caterpillar deterrence. Using concentrations that reflect the foliar levels of hederagenin-type saponins, the sapogenin hederagenin was not toxic to 4th instar caterpillars of the cabbage looper Trichoplusia ni nor did it act as a feeding deterrent. Female caterpillars consumed more diet than males, presumably to obtain the additional nutrients required for oogenesis, and are, thus, exposed to higher hederagenin levels...
March 5, 2024: Journal of Chemical Ecology
#38
JOURNAL ARTICLE
Henry Wyneken, Kelly N Kim, Audrey A Cerles, Christine Heren, Sydney Bowman, Emma J Reuter, Colin McCarty, Kaylin Chen, Sean Daly, Lauren Gherman, Iqra Imran, Jenna Marcopul, Alannah Miller, Andrea Valladares, Caitlin Wrinn, Adam E J Fleming, Rebecca Roberts, Rocco Casagrande
INTRODUCTION: Threaded conical centrifuge tubes are ubiquitous in biological laboratories and are frequently used for the storage/transport of potentially biohazardous samples. However, limited data are available on how frequently and from where these tubes leak. These data are valuable for laboratory biorisk management and to inform future studies on risks arising from the routine use of laboratory consumables. METHODS: The frequency of leaks from threaded conical centrifuge tubes was tested using a Glo Germ solution as a tracer...
March 1, 2024: Applied Biosafety: Journal of the American Biological Safety Association
#39
JOURNAL ARTICLE
Jessica M Duda, Amelia D Moser, Maria Ironside, Kaylee E Null, Laura M Holsen, Chun S Zuo, Fei Du, Shiba M Esfand, Xi Chen, Sarah Perlo, Christine E Richards, Rachel Lobien, Madeline Alexander, Madhusmita Misra, Jill M Goldstein, Diego A Pizzagalli
BACKGROUND: Neurocognitive factors including aberrant reward learning, blunted gamma-aminobutyric acid (GABA), and potentiated stress sensitivity have been linked to anhedonia, a hallmark depressive symptom, possibly in a sex-dependent manner. However, past research has not investigated the putative associations among these factors nor the extent to which they represent trait- or state-based vulnerabilities for depression. METHODS: Young adults with current major depressive disorder, (MDD; N=44), remitted MDD (rMDD; N=42), and healthy control participants (HC; N=44), stratified by sex, underwent magnetic resonance spectroscopy to assess GABA+ (macromolecular contaminated), and then a reward learning task before and after acute stress...
February 26, 2024: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
#40
JOURNAL ARTICLE
Felicia Roncolato, Madeleine T King, Rachel L O'Connell, Yeh Chen Lee, Florence Joly, Felix Hilpert, Anne Lanceley, Yoshio Yoshida, Jane Bryce, Paul Donnellan, Amit Oza, Elisabeth Avall-Lundqvist, Jonathan S Berek, Jonathan A Ledermann, Dominique Berton, Jalid Sehouli, Marie-Christine Kaminsky, Martin R Stockler, Michael Friedlander
OBJECTIVE: To describe the baseline symptom burden(SB) experienced by patients(pts) with recurrent ovarian cancer(ROC) prior and associations with progression free survival (PFS) and overall survival (OS). METHODS: We analysed baseline SB reported by pts. with platinum resistant/refractory ROC (PRR-ROC) or potentially‑platinum sensitive ROC receiving their third or greater line of chemotherapy (PPS-ROC≥3) enrolled in the Gynecologic Cancer InterGroup - Symptom Benefit Study (GCIG-SBS) using the Measure of Ovarian Symptoms and Treatment concerns (MOST)...
February 26, 2024: Gynecologic Oncology
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