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https://www.readbyqxmd.com/read/29352665/complementary-and-alternative-medicine-cam-practices-and-dietary-patterns-in-children-with-inflammatory-bowel-disease-in-singapore-and-malaysia
#1
Fangyi Ong, Way Seah Lee, Charlotte Lin, Ruey Terng Ng, Shin Yee Wong, Su Lin Lim, Seng Hock Quak, Marion Aw
BACKGROUND: The use of complementary and alternative medicine (CAM) has been associated with adverse effects and self-imposed dietary restrictions. The prevalence of its use in Asian children with inflammatory bowel disease (IBD) is unknown. We aimed to determine the prevalence, types, and factors associated with the use of CAM among children with IBD from Singapore and Malaysia, and to ascertain if dietary restriction was prevalent in patients who used CAM. METHODS: A cross-sectional study was conducted in which parents of children with IBD attending two tertiary pediatric IBD referral centres in Singapore and Malaysia were interviewed...
December 26, 2017: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/29350457/improved-outcome-at-end-of-treatment-in-the-collaborative-wilms-tumour-africa-project
#2
Trijn Israels, Vivian Paintsil, Dalida Nyirenda, Francine Kouya, Glenn Mbah Afungchwi, Peter Hesseling, Clara Tump, Gertjan Kaspers, Liz Burns, Ramandeep Singh Arora, George Chagaluka, Philippa Nana, Lorna Renner, Elizabeth Molyneux
BACKGROUND: The Collaborative Wilms Tumour (WT) Africa Project has implemented an adapted WT treatment guideline in sub-Saharan Africa as a multi-centre prospective clinical trial. A retrospective, baseline evaluation of end-of-treatment outcome was performed for a 2-year period prior to the introduction of this guideline. The collaborative project aims to reduce both treatment abandonment and death during treatment to less than 10% for improving survival. PROCEDURE: All participating centres obtained local Institutional Research Board (IRB) approval and implemented the adapted WT treatment guideline...
January 19, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29349778/intrathecal-baclofen-therapy-in-children-an-analysis-of-individualized-goals
#3
Peck Yee Liew, Kirsty Stewart, Debra Khan, Sarah Jane Arnup, Adam Scheinberg
AIM: To determine whether intrathecal baclofen (ITB) therapy improves performance and performance satisfaction in goal areas identified by patients' parents. METHOD: This study formed part of an ongoing multicentre national audit involving six paediatric ITB pump implant centres across Australia. The Canadian Occupational Performance Measure was the primary outcome measure utilized at baseline, 6 months, and 12 months after pump implants in paediatric patients receiving ITB therapy for the first time between 31st December 2009 and 31st December 2014...
January 19, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/29349602/does-the-interval-from-tumour-surgery-to-radiotherapy-influence-survival-in-paediatric-high-grade-glioma
#4
Amedeo A Azizi, Simon Paur, Alexandra Kaider, Karin Dieckmann, Andreas Peyrl, Monika Chocholous, Thomas Czech, Irene Slavc
PURPOSE: Paediatric high grade glioma (pHGG) are rare. Following maximum safe resection, children >3 years with HGG receive radiotherapy as standard of care. Whether the interval from tumour surgery to radiotherapy (ISRT) influences survival is disputed in adults with glioblastoma, data for children are lacking. This retrospective single-centre analysis investigates a possible impact of ISRT on survival in paediatric patients with HGG. METHODS: Survival was analysed in patients aged 3-19 years with non-pontine HGG...
January 18, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/29347833/how-should-we-understand-family-centred-care
#5
Suzanne Uniacke, Tamara Kayali Browne, Linda Shields
What is family-centred care of a hospitalized child? A critical understanding of the concept of family-centred care is necessary if this widely preferred model is to be differentiated from other health care ideals and properly evaluated as appropriate to the care of hospitalized children. The article identifies distinguishable interpretations of family-centred care that can pull health professionals in different, sometimes conflicting directions. Some of these interpretations are not qualitatively different from robust interpretations of the ideals of parental participation, care-by-parent and partnership in care that are said to be the precursors of family-centred care...
January 1, 2018: Journal of Child Health Care: for Professionals Working with Children in the Hospital and Community
https://www.readbyqxmd.com/read/29345224/therapy-interventions-for-children-with-neurodisabilities-a-qualitative-scoping-study
#6
Bryony Beresford, Susan Clarke, Jane Maddison
BACKGROUND: Therapy interventions emerged four times in the top 10 research priorities in a James Lind Alliance research prioritisation exercise for children with neurodisabilities (Morris C, Simkiss D, Busk M, Morris M, Allard A, Denness J, et al. Setting research priorities to improve the health of children and young people with neurodisability: a British Academy of Childhood Disability-James Lind Alliance Research Priority Setting Partnership. BMJ Open 2015;5:e006233). The National Institute for Health Research (NIHR) commissioned this study as part of an information-gathering exercise in response to this...
January 2018: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29344875/development-of-a-prognostic-prediction-model-to-determine-severe-dengue-in-children
#7
Priya Sreenivasan, Geetha S, Sasikala K
OBJECTIVE: To develop a prognostic prediction model using the seven warning signs highlighted by WHO revised Dengue fever classification 2009 to determine severe dengue in children. METHODS: In this prospective analytical study conducted in a tertiary care centre, consecutive sampling of all children aged 1mo to 12y admitted with serologically confirmed Dengue was done from May 2015 through August 2016. After excluding 27 patients with co-infections and co-morbidities, 359 patients were followed up daily to assess clinical and laboratory progression till discharge/ death...
January 18, 2018: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29341155/long-term-outcome-of-prophylactic-thyroidectomy-in-children-carrying-ret-germline-mutations
#8
A Machens, M Elwerr, K Lorenz, F Weber, H Dralle
BACKGROUND: A comprehensive assessment has not been undertaken of long-term outcomes in children carrying germline RET mutations and undergoing prophylactic thyroidectomy with the aim of preventing medullary thyroid cancer (MTC). METHODS: A retrospective outcome study (1994-2017) of prophylactic thyroidectomy in children, with and without central node dissection, was performed at a tertiary surgical centre. RESULTS: Some 167 children underwent prophylactic thyroidectomy, 109 without and 58 with concomitant central node dissection...
January 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29340791/treatment-of-disabling-headache-with-greater-occipital-nerve-injections-in-a-large-population-of-childhood-and-adolescent-patients-a-service-evaluation
#9
Francesca Puledda, Peter J Goadsby, Prab Prabhakar
BACKGROUND: Pediatric headache disorders can be extremely disabling, with marked reduction in the quality of life of children and their carers. Evidenced-based options for the treatment of primary headache disorders with preventive medication is limited and clinical outcomes are often unsatisfactory. Greater occipital nerve injections represent a rapid and well-tolerated therapeutic option, which is widely used in clinical practice in adults, and has previously shown a good outcome in a pediatric population...
January 16, 2018: Journal of Headache and Pain
https://www.readbyqxmd.com/read/29338904/pain-and-its-impact-on-the-functional-ability-in-children-treated-at-the-children-s-cancer-center-of-lebanon
#10
Dina Madi, Michael Clinton
PURPOSE: The purpose of this study was to describe the characteristics of pain in children under treatment at the Children Cancer Centre of Lebanon at the American University of Beirut Medical Centre. Design and Methods A cross-sectional correlational survey was used. The Adolescent Pediatric Pain Tool and the Functional Disability Inventory were used to examine the characteristics of pain experienced in a consecutive sample of children treated at the CCCL and its impact on their functional abilities...
January 12, 2018: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29338123/choroidal-thickness-and-myopia-in-relation-to-physical-activity-the-champs-eye-study
#11
Kristian Lundberg, Anders Højslet Vestergaard, Nina Jacobsen, Anne Suhr Thykjaer, Rasmus Søgaard Hansen, Ernst Goldschmidt, Tunde Peto, Ulrich Halekoh, Niels Wedderkopp, Jakob Grauslund
PURPOSE: To describe the relationship between choroidal thickness (CT) and myopia in relation to physical activity (PA) in a population-based child cohort. METHODS: In a prospective study of 307 children from the CHAMPS Study Denmark, we used objective data from GT3X accelerometer worn at four periods between 2009 and 2015 to determine the amount and intensity of PA. Intensity was estimated as counts/minutes, and cut-off points were defined at four intensity levels...
January 16, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29338012/using-geospatial-techniques-to-develop-an-emergency-referral-transport-system-for-suspected-sepsis-patients-in-bangladesh
#12
Atique Iqbal Chowdhury, Rafiqul Haider, Abu Yousuf Md Abdullah, Aliki Christou, Nabeel Ashraf Ali, Ahmed Ehsnaur Rahman, Afrin Iqbal, Sanwarul Bari, D M Emdadul Hoque, Shams El Arifeen, Niranjan Kissoon, Charles P Larson
BACKGROUND: A geographic information system (GIS)-based transport network within an emergency referral system can be the key to reducing health system delays and increasing the chances of survival, especially during an emergency. We employed a GIS to design an emergency transport system for the rapid transfer of pregnant or early post-partum women, newborns, and children under 5 years of age with suspected sepsis under the Interrupting Pathways to Sepsis Initiative (IPSI) project. METHODS: A GIS database was developed by mapping the villages, roads, and relevant physical features of the study area...
2018: PloS One
https://www.readbyqxmd.com/read/29337407/insufficient-sleep-syndrome-an-unrecognized-but-important-clinical-entity
#13
Jun Kohyama, Yuki Anzai, Makoto Ono, Ai Kishino, Keita Tamanuki, Kazuma Takada, Kento Inoue, Maho Horiuchi, Yoshiho Hatai
BACKGROUND: In the Tokyo Bay Urayasu Ichikawa Medical Centre, a sleep clinic for adults and children was established in August 2012. As few sleep clinics are available in Japan that are specifically for children, this clinic provides the opportunity to provide data on child patients who have been suffering from sleep problems and who visited the sleep clinic. METHODS: Records of patients who visited the sleep clinic at the Tokyo Bay Urayasu Ichikawa Medical Centre at the age of 20 years or younger on their first visit were retrospectively examined, and their initial and final diagnoses were examined...
January 16, 2018: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/29335155/investigating-the-potential-impact-of-dose-banding-for-systemic-anti-cancer-therapy-in-the-paediatric-setting-based-on-pharmacokinetic-evidence
#14
Melanie White-Koning, Caroline Osborne, Angelo Paci, Alan V Boddy, Etienne Chatelut, Gareth J Veal
BACKGROUND: To make systemic anti-cancer therapy (SACT) preparation more practicable, dose-banding approaches are currently being introduced in many clinical centres. The present study aimed to determine the potential impact of using recently developed National Health Service in England (NHSE) dose-banding tables in a paediatric setting. METHODS: Using pharmacokinetic parameters obtained from 385 drug administrations in 352 children aged from 1 month to 18 years, treated with five drugs (dactinomycin, busulfan, carboplatin, cyclophosphamide and etoposide), individual exposures (area under the plasma drug concentration versus time curve; AUC) obtained using doses rounded according to the published NHSE tables were calculated and compared with those obtained by standard dose calculation methods...
January 12, 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29335026/congenital-anomalies-in-neurofibromatosis-1-a-retrospective-register-based-total-population-study
#15
Jussi Leppävirta, Roope A Kallionpää, Elina Uusitalo, Tero Vahlberg, Minna Pöyhönen, Juha Peltonen, Sirkku Peltonen
BACKGROUND: Neurofibromatosis type 1 (NF1) is a dominantly inherited Rasopathy caused by mutations in the NF1 gene on chromosome 17. NF1 has been connected to congenital anomalies, e.g., in the skeletal and cardiovascular systems, but the overall incidence of anomalies is unknown. In this retrospective register-based total population study conducted in Finland, the congenital anomalies in NF1 were evaluated. METHODS: One thousand four hundred ten patients with NF1 were identified by searching the medical records related to inpatient and outpatient hospital visits of patients with an associated diagnosis for NF1 in 1987-2011...
January 15, 2018: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/29334972/community-readiness-assessment-for-obesity-research-pilot-implementation-of-the-healthier-families-programme
#16
Leah A Teeters, William J Heerman, David Schlundt, Dawn Harris, Shari L Barkin
BACKGROUND: This article reports on the development of a systematic approach to assess for community readiness prior to implementation of a behavioural intervention for childhood obesity. Using the Consolidated Framework for Implementation Research (CFIR), we developed research tools to evaluate local community centres' organisational readiness and their capacity to implement the intervention. METHODS: Four community Parks and Recreation centres from different states expressed interest in piloting an approach for dissemination and implementation of an evidence-based obesity prevention program for families with young children (Healthier Families)...
January 15, 2018: Health Research Policy and Systems
https://www.readbyqxmd.com/read/29334933/temporary-exclusion-of-ill-children-from-childcare-centres-in-switzerland-practice-problems-and-potential-solutions
#17
Benjamin Sticher, Julia Bielicki, Christoph Berger
BACKGROUND: In childcare centres, temporary exclusion of ill children, if their illness poses a risk of spread of harmful diseases to others, is a central approach to fight disease transmission. However, not all ill children need to be excluded. Previous studies suggested that childcare centre staff have difficulties in deciding whether or not to exclude an ill child, even when official ill-child guidelines are used. We aimed to describe, quantify and analyse these ambiguities and discuss potential solutions...
January 15, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29334920/factors-influencing-access-of-pregnant-women-and-their-infants-to-their-local-healthcare-system-a-prospective-multi-centre-observational-study
#18
Shabir A Madhi, Luis M Rivera, Xavier Sáez-Llorens, Clara Menéndez, Nazira Carrim-Ganey, Mark F Cotton, Darren Katzman, Mariëtha M Luttig, Rosalba Candelario, Sherryl Baker, Mahua Roychoudhury
BACKGROUND: The successful implementation of maternal vaccination relies on results of clinical trials, considering the prenatal and postnatal attendance at selected healthcare institutions. This study evaluated factors influencing maternal/infant access to healthcare facilities to identify potential barriers to participation in future clinical trials on maternal vaccination. METHODS: In this prospective, multi-centre, observational study, pregnant women (N = 3243) were enrolled at ten sites across Panama, the Dominican Republic, South Africa, and Mozambique between 2012 and 2014...
January 15, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29334809/accidental-pharmacological-poisonings-in-young-children-population-based-study-in-three-settings
#19
Jane C Bell, Jason P Bentley, Catriona Downie, Rose Cairns, Nicholas A Buckley, Annette Katelaris, Sallie-Anne Pearson, Natasha Nassar
INTRODUCTION: Pharmacological poisonings in young children are avoidable. Previous studies report calls to poisons centres, presentations to emergency departments (ED) or hospital admissions. There are limited data assessing concurrent management of poisonings across all three settings. We aimed to describe accidental pharmacological poisonings in young children across our Poisons Information Centre (PIC), EDs and hospitals. METHODS: A population-based study in New South Wales, Australia, of PIC calls, ED presentations and hospital admissions for accidental pharmacological poisoning in children aged <5 years, 2007-2013...
January 15, 2018: Clinical Toxicology
https://www.readbyqxmd.com/read/29334792/mothers-opinions-on-being-asked-about-exposure-to-intimate-partner-violence-in-child-healthcare-centres-in-sweden
#20
Kjerstin Almqvist, Åsa Källström, Petra Appell, Agneta Anderzen-Carlsson
Intimate partner violence (IPV) constitutes a hidden health risk for exposed mothers and children. In Sweden, screening for IPV in healthcare has only been routine during pregnancy, despite an increase in IPV following childbirth. The arguments against routine questions postpartum have concerned a lack of evidence of beneficial effects as well as fear of stigmatizing women or placing abused women at further risk. Increased understanding of women's attitudes to routine questions may allay these fears. In this study, 198 mothers in 12 child healthcare centres (CHCs) filled in a short questionnaire about their exposure and received information on IPV at a regular baby check-up visit...
January 1, 2018: Journal of Child Health Care: for Professionals Working with Children in the Hospital and Community
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