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Trauma responses

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https://www.readbyqxmd.com/read/27906447/validation-of-the-parental-facilitation-of-mastery-scale-ii
#1
Alyson K Zalta, Kelly M Allred, Eranda Jayawickreme, Laura E R Blackie, Dianne L Chambless
To develop a more reliable and comprehensive version of the Parental Facilitation of Mastery Scale (PFMS) METHOD: In Study 1, 387 undergraduates completed an expanded PFMS (PFMS-II) and measures of parenting, perceived control, responses to early life challenges, and psychopathology. In Study 2, 182 trauma-exposed community participants completed the PFMS-II and measures of perceived control, psychopathology, and well-being RESULTS: In Study 1, exploratory factor analysis of the PFMS-II revealed two factors...
December 1, 2016: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/27905913/sera-from-severe-trauma-patients-with-pneumonia-and-without-infectious-complications-have-differential-effects-on-neutrophil-biology
#2
B Relja, R Taraki, M P J Teuben, K Mörs, N Wagner, S Wutzler, F Hildebrand, M Perl, I Marzi
BACKGROUND: Major trauma patients (TP) developing imbalanced immune response are at high risk for infectious post-injury complications including pneumonia. Neutrophils play a central role in the host defense against bacteria and thereby pathogenesis of infections. While there are numerous studies about neutrophil function after trauma, data about their biology in patients who suffer from pneumonia following trauma are sparse. Here, we studied the effect of serum isolated from patients who do and do not develop infection (inf...
December 1, 2016: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/27901414/cognitive-deficits-and-inflammatory-response-resulting-from-mild-to-moderate-traumatic-brain-injury-in-rats-are-exacerbated-by-repeated-pre-exposure-to-an-innate-stress-stimulus
#3
Michaël Ogier, Amor Belmeguenai, Thomas Lieutaud, Béatrice Georges, Sandrine Bouvard, Emilie Carré, Frédéric Canini, Laurent Bezin
Traumatic brain injury (TBI) is common in both military and civilian populations, and often results in neurobehavioral sequelae that impair quality of life in both patients and their family. Although individuals who are chronically exposed to stress are more likely to experience TBI, it is still unknown whether pre-injury stress influences the outcome after TBI. The present study tested whether behavioral and cognitive long-term outcome after TBI in rats is affected by prior exposure to an innate stress stimulus...
November 30, 2016: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27900778/predicting-post-traumatic-stress-disorder-treatment-response-in-refugees-multilevel-analysis
#4
Joris F G Haagen, F Jackie June Ter Heide, Trudy M Mooren, Jeroen W Knipscheer, Rolf J Kleber
OBJECTIVES: Given the recent peak in refugee numbers and refugees' high odds of developing post-traumatic stress disorder (PTSD), finding ways to alleviate PTSD in refugees is of vital importance. However, there are major differences in PTSD treatment response between refugees, the determinants of which are largely unknown. This study aimed at improving PTSD treatment for adult refugees by identifying PTSD treatment response predictors. DESIGN: A prospective longitudinal multilevel modelling design was used to predict PTSD severity scores over time...
November 30, 2016: British Journal of Clinical Psychology
https://www.readbyqxmd.com/read/27899434/development-of-cgrp-dependent-pain-and-headache-related-behaviours-in-a-rat-model-of-concussion-implications-for-mechanisms-of-post-traumatic-headache
#5
Dara Bree, Dan Levy
BACKGROUND AND OBJECTIVE: Posttraumatic headache (PTH) is one of the most common, debilitating and difficult symptoms to manage after a mild traumatic brain injury, or concussion. However, the mechanisms underlying PTH remain elusive, in part due to the lack of a clinically relevant animal model. Here, we characterized for the first time, headache and pain-related behaviours in a rat model of concussion evoked by a mild closed head injury (mCHI) - the major type of military and civilian related trauma associated with PTH - and tested responses to current and novel headache therapies...
November 29, 2016: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/27897127/effects-of-noise-exposure-on-the-auditory-function-of-ovariectomized-rats-with-estrogen-deficiency
#6
Xujun Hu, Ying Wang, Chi Chuen Lau
OBJECTIVE: The benefits of estrogen for the auditory function of women depend on a number of factors. In this study, we aimed to examine the impact of noise trauma on the auditory function of ovariectomized rats with estrogen deficiency. MATERIALS AND METHODS: Twenty-eight young, female Sprague-Dawley rats were assigned to three groups (OVX+N, OVX-N, Sham+N). Rats in the OVX+N group and the OVX-N group underwent bilateral ovariectomy (OVX); the OVX+N group alone was also exposed to white noise (N) of 115 dB SPL for 8 hours a day over 14 days...
November 28, 2016: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/27896407/mixed-methods-assessment-of-trauma-and-acute-care-surgical-quality-improvement-programs-in-peru
#7
Lacey N LaGrone, Amy K Fuhs, Eduardo Huaman Egoavil, Manuel J A Rodriguez Castro, Roberto Valderrama, Leah N Isquith-Dicker, Jaime Herrera-Matta, Charles N Mock
BACKGROUND: Evidence for the positive impact of quality improvement (QI) programs on morbidity, mortality, patient satisfaction, and cost is strong. Data regarding the status of QI programs in low- and middle-income countries, as well as in-depth examination of barriers and facilitators to their implementation, are limited. METHODS: This cross-sectional, descriptive study employed a mixed-methods design, including distribution of an anonymous quantitative survey and individual interviews with healthcare providers who participate in the care of the injured at ten large hospitals in Lima, Peru...
November 28, 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/27896177/anti-vascular-endothelial-growth-factor-bevacizumab-therapy-reduces-hypertrophic-scar-formation-in-a-rabbit-ear-wounding-model
#8
Do Hoon Kwak, Tae Hui Bae, Woo Seob Kim, Han Koo Kim
BACKGROUND: Hypertrophic scarring is a pathological condition that occurs after trauma or surgery. Angiogenesis occurs more often with hypertrophic scarring than with normotrophic scarring. The regulation of angiogenesis is one of the key factors in hypertrophic scar management. Vascular endothelial growth factor (VEGF) is an essential factor in the angiogenetic response. This study investigated whether decreasing the level of VEGF is effective for treating hypertrophic scarring. METHODS: Ten 8-week-old female New Zealand white rabbits were included...
November 2016: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/27894496/postinjury-inflammation-and-organ-dysfunction
#9
REVIEW
Angela Sauaia, Frederick A Moore, Ernest E Moore
The development of organ dysfunction (OD) is related to the intensity and balance between trauma-induced simultaneous, opposite inflammatory responses. Early proinflammation via innate immune system activation may cause early OD, whereas antiinflammation, via inhibition of the adaptive immune system and apoptosis, may induce immunoparalysis, impaired healing, infections, and late OD. Patients discharged with low-level OD may develop the persistent inflammation-immunosuppression catabolism syndrome. Although the incidence of multiple organ failure has decreased over time, it remains morbid, lethal, and resource intensive...
January 2017: Critical Care Clinics
https://www.readbyqxmd.com/read/27893549/how-deleterious-is-facial-nerve-dissection-for-the-facial-nerve-in-parotid-surgery-an-electrophysiological-evaluation
#10
Sabri Baki Eren, Remzi Dogan, Orhan Ozturan, Bayram Veyseller, Ayşenur Meriç Hafiz
OBJECTIVE: This study was conducted to investigate subclinical electrophysiological deleterious effect due to microtrauma to the nerve in response to the dissection of a tumor and parotid tissue from the facial nerve and its branches and surgical traction experienced during the operation. METHODS: The study included 34 adult patients who underwent parotidectomy operations under intraoperative facial nerve monitoring. Three measurements were taken from each patient to evaluate facial nerve functions, with 3 stimuli of different intensities applied with different timing...
November 23, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27893181/synaesthesia-lost-and-found-two-cases-of-person-and-music-colour-synaesthesia
#11
Francesca R Farina, Kevin J Mitchell, Richard A P Roche
Synaesthesia is a developmental condition involving cross-communication between sensory modalities or substreams whereby an inducer (e.g. a sound) automatically evokes a concurrent percept in another modality (e.g. a colour). Whether this condition arises due to atypical structural connectivity (e.g., between normally unconnected cortical areas) or altered neurochemistry remains a central question. We report the exceptional cases of two synaesthetes - subjects AB and CD - both of whom experience coloured auras around individuals, as well as coloured perceptions in response to music...
November 28, 2016: European Journal of Neuroscience
https://www.readbyqxmd.com/read/27893012/surgeons-and-trauma-care-physicians-perception-of-the-impact-of-the-globalization-of-medical-education-on-quality-of-care-in-lima-peru
#12
Lacey N LaGrone, Leah N Isquith-Dicker, Eduardo Huaman Egoavil, Manuel J A Rodriguez Castro, Alfredo Allagual, Fernando Revoredo, Charles N Mock
Importance: The globalization of medical education-the process by which trainees in any region gain access to international training (electronic or in-person)-is a growing trend. More data are needed to inform next steps in the responsible stewardship of this process, from the perspective of trainees and institutions at all income levels, and for use by national and international policymakers. Objective: To describe the impact of the globalization of medical education on surgical care in Peru from the perspective of Peruvian surgeons who received international training...
November 23, 2016: JAMA Surgery
https://www.readbyqxmd.com/read/27891481/a-large-pregnancy-tumor-of-tongue-a-case-report
#13
U Arunmozhi, R Shanmuga Priya, R Kadhiresan, Govindarajan Sujatha, Shaik M Shamsudeen-Ss
Pyogenic granuloma is a tissue overgrowth which commonly develops as a response to irritation or trauma which is usually localized. Though gingiva is said to be the common site, it also can occur on lip, tongue and buccal mucosa. Pathogenesis is unclear but trauma, infection and hormonal imbalance are attributed as reasons for occurrence. Histologically this reactive lesion is filled with immature fibroblastic connective tissue, profilerative blood vessels and inflammatory cells. This article presents a case of a large pyogenic granuloma of the tongue which is a rare site for this tumor in a 27 year old woman...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27891152/venipuncture-induced-complex-regional-pain-syndrome-presenting-as-inflammatory-arthritis
#14
Punit Pruthi, Pramod Arora, Manoj Mittal, Anugrah Nair, Waqia Sultana
Venipuncture is one of the most commonly done medical procedures. We report a unique case of a 23-year-old young male who presented with features suggestive of inflammatory arthritis. The symptoms, which initially started on the right side, also involved the other side after a few weeks. Although the patient's symptoms and signs were simulating inflammatory arthritis, he had atypical features like poor response to anti-inflammatory medicines and normal laboratory parameters. His musculoskeletal ultrasonography was also not suggestive of arthritis...
2016: Case Reports in Medicine
https://www.readbyqxmd.com/read/27890150/assessing-ergonomic-risks-of-software-development-of-the-seat
#15
S Camille Peres, Ranjana K Mehta, Paul Ritchey
Software utilizing interaction designs that require extensive dragging or clicking of icons may increase users' risks for upper extremity cumulative trauma disorders. The purpose of this research is to develop a Self-report Ergonomic Assessment Tool (SEAT) for assessing the risks of software interaction designs and facilitate mitigation of those risks. A 28-item self-report measure was developed by combining and modifying items from existing industrial ergonomic tools. Data were collected from 166 participants after they completed four different tasks that varied by method of input (touch or keyboard and mouse) and type of task (selecting or typing)...
March 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/27889894/glucocorticoid-induced-leucine-zipper-in-central-nervous-system-health-and-disease
#16
REVIEW
Mythily Srinivasan, Debomoy K Lahiri
The central nervous system (CNS) is a large network of intercommunicating cells that function to maintain tissue health and homeostasis. Considerable evidence suggests that glucocorticoids exert both neuroprotective and neurodegenerative effects on the CNS. Glucocorticoids act by binding two related receptors in the cytoplasm, the mineralocorticoid receptor (MR) and the glucocorticoid receptor (GR). The glucocorticoid receptor complex mediates cellular responses by transactivating target genes and by protein: protein interactions...
November 26, 2016: Molecular Neurobiology
https://www.readbyqxmd.com/read/27889267/attribution-2-0-whose-complication-is-it
#17
Greg Hambright, Theresa Jackson, Vaidehi Agrawal, Antonio Arazosa, Benjamin Newman, Michael S Truitt
BACKGROUND: Payment models aimed at improving quality and curbing costs are being deployed, and hospitals are evaluating complications more closely. To decrease complications, hospitals must first "attribute" them to a responsible party. Our study uses a rigorous approach to attribution in the trauma population. METHODS: Twelve months of complications were reviewed by a multidisciplinary panel. Physicians, patients, nursing, and the hospital were all incorporated into the model...
September 28, 2016: American Journal of Surgery
https://www.readbyqxmd.com/read/27889010/neuropsychiatric-aspects-of-concussion
#18
REVIEW
Rajiv Radhakrishnan, Amir Garakani, Lawrence S Gross, Marcia K Goin, Janet Pine, Andrew E Slaby, Calvin R Sumner, David A Baron
Over the past decade, concussion has become the most widely discussed injury in contact sports. However, concussions also occur in several other settings, such as non-contact sports, elderly individuals, young children, military personnel, and victims of domestic violence. Concussion is frequently undiagnosed as a cause of psychiatric morbidity, especially when the patient has no history of loss of consciousness or direct head trauma. Almost all of the extant literature focuses on traumatic brain injury and assumes that concussion is merely a mild form of traumatic brain injury, which has resulted in a lack of understanding about what concussion is, and how to diagnose, monitor, and treat its varied neuropsychiatric symptoms...
December 2016: Lancet Psychiatry
https://www.readbyqxmd.com/read/27882160/disseminated-nocardiosis-caused-by-nocardia-otitidiscaviarum-in-an-immunocompetent-host-a-case-report-and-literature-review
#19
Yanwen Jiang, Aiben Huang, Qiuhong Fang
The aim of the present study was to summarize the clinical characteristics of nocardiosis caused by Nocardia otitidiscaviarum in order to improve the knowledge of nocardiosis. A case of dissemination nocardiosis caused by N. otitidiscaviarum in an immunocompetent host is reported and the associated literature reviewed. Informed consent for publication of this case report was provided by the patient. The present patient was a young immunocompetent man suffering from disseminated nocardiosis induced by infection with N...
November 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27881686/in-their-own-words-exploring-family-pathways-to-housing-instability
#20
Laura Gultekin, Barbara L Brush
Housing instability threatens the health and well-being of millions of families across the United States, yet little is known about the characteristics or housing trajectories of at-risk families. To address this gap in our understanding of family risk for housing instability and homelessness, we undertook a qualitative descriptive study utilizing a convenience sample of 16 mothers recruited from a housing service agency living in Detroit and receiving emergency services to avoid homelessness. Participants completed the Brief Patient Health Questionnaire (PHQ), then narrated their life events and reasons for housing instability and disclosed desired interventions for homelessness prevention...
November 22, 2016: Journal of Family Nursing
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