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https://www.readbyqxmd.com/read/28930264/essential-oil-from-piper-aduncum-chemical-analysis-antimicrobial-assessment-and-literature-review
#1
Lianet Monzote, Ramón Scull, Paul Cos, William N Setzer
Background: The challenge in antimicrobial chemotherapy is to find safe and selective agents with potency that will not be compromised by previously developed resistance. Terrestrial plants could provide new leads to antibacterial, antifungal, or antiprotozoal activity. Methods: The essential oil (EO) of Piper aduncum L. (Piperaceae) from Cuba was analyzed by gas chromatography-mass spectrometry (GC-MS). A cluster analysis of P. aduncum EO compositions reported in the literature was carried out. The EO was screened against a panel of microorganisms (bacteria, fungi, parasitic protozoa) as well as for cytotoxicity against human cells...
July 2, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28912065/taino-and-african-maternal-heritage-in-the-greater-antilles
#2
Areej Bukhari, Javier Rodriguez Luis, Miguel A Alfonso-Sanchez, Ralph Garcia-Bertrand, Rene J Herrera
Notwithstanding the general interest and the geopolitical importance of the island countries in the Greater Antilles, little is known about the specific ancestral Native American and African populations that settled them. In an effort to alleviate this lacuna of information on the genetic constituents of the Greater Antilles, we comprehensively compared the mtDNA compositions of Cuba, Dominican Republic, Haiti, Jamaica and Puerto Rico. To accomplish this, the mtDNA HVRI and HVRII regions, as well as coding diagnostic sites, were assessed in the Haitian general population and compared to data from reference populations...
September 11, 2017: Gene
https://www.readbyqxmd.com/read/28911064/cancer-mortality-predictions-for-2017-in-latin-america
#3
G Carioli, C La Vecchia, P Bertuccio, T Rodriguez, F Levi, P Boffetta, E Negri, M Malvezzi
Background: From most recent available data, we predicted cancer mortality statistics in selected Latin American countries for the year 2017, with focus on lung cancer. Materials and methods: We obtained death certification data from the World Health Organization and population data from the Pan American Health Organization database for all neoplasms and selected cancer sites. We derived figures for Argentina, Brazil, Chile, Colombia, Cuba, Mexico and Venezuela...
September 1, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28905125/biometeorological-forecasts-for-health-surveillance-and-prevention-of-meteor-tropic-effects
#4
Luis B Lecha Estela
An early method of biometeorological forecasts was developed for Cuba during the late 90s. It was based on the relationship between the daily occurrence of massive health crisis and the magnitude of the 24-h differences of partial density of oxygen in the air (PODA index). Ten years later, applying new technological facilities, a new model was developed in order to offer operational biometeorological forecast to Cuban health institutions. After a satisfactory validation process, the official bioforecast service to health institutions in Villa Clara province began on February of 2012...
September 13, 2017: International Journal of Biometeorology
https://www.readbyqxmd.com/read/28895430/a-homozygous-mutation-in-the-psmb8-gene-in-a-case-with-proteasome-associated-autoinflammatory-syndrome
#5
C Contreras-Cubas, A Cárdenas-Conejo, A Rodríguez-Velasco, H García-Ortiz, L Orozco, V Baca
No abstract text is available yet for this article.
September 12, 2017: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/28885225/rey-osterrieth-complex-figure-copy-and-immediate-recall-3-minutes-normative-data-for-spanish-speaking-pediatric-populations
#6
J C Arango-Lasprilla, D Rivera, M M Erlt, J M Muñoz Mancilla, C E García-Guerrero, W Rodriguez-Irizarry, A Aguayo Arelis, Y Rodríguez-Agudelo, M D Barrios Nevado, M Vélez-Coto, T P Yacelga Ponce, A Rigabert, C García de la Cadena, S Pohlenz Amador, E Vergara-Moragues, M Soto-Añari, A I Peñalver Guia, M Saracostti Schwartzman, R Ferrer-Cascales
OBJECTIVE: To generate normative data for the Rey- Osterrieth Complex Figure (ROCF) in Spanish-speaking pediatric populations. METHOD: The sample consisted of 4,373 healthy children from nine countries in Latin America (Chile, Cuba, Ecuador, Guatemala, Honduras, Mexico, Paraguay, Peru, and Puerto Rico) and Spain. Each participant was administered the ROCF as part of a larger neuropsychological battery. The ROCF copy and immediate recall (3 minutes) scores were normed using multiple linear regressions and standard deviations of residual values...
September 5, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28877361/-enticing-case-study-or-celebrated-anomaly-policy-learning-from-the-cuban-health-system
#7
Rob Baggott, George Lambie
Cuba is regarded as having achieved very good health outcomes for its level of economic development. It has adopted policies and programs that focus on prevention, universal access to healthcare, a strong primary care system, the integration of health in all policies, and public participation in health. It has also established a strong and accessible system of medical education and provides substantial medical aid and support to other countries. Why then, it may be asked, has the Cuban experience not had greater influence on health policies and reforms elsewhere? This article, based on a literature review and new primary sources, analyzes various factors highlighted in the policy transfer literature to explain this...
September 6, 2017: International Journal of Health Planning and Management
https://www.readbyqxmd.com/read/28866745/mortality-and-prognostic-factors-in-idiopathic-inflammatory-myositis-a-retrospective-analysis-of-a-large-multicenter-cohort-of-spain
#8
Laura Nuño-Nuño, Beatriz Esther Joven, Patricia E Carreira, Valentina Maldonado-Romero, Carmen Larena-Grijalba, Irene Llorente Cubas, Eva Gloria Tomero, María Carmen Barbadillo-Mateos, Paloma García De la Peña Lefebvre, Lucía Ruiz-Gutiérrez, Juan Carlos López-Robledillo, Henry Moruno-Cruz, Ana Pérez, Tatiana Cobo-Ibáñez, Raquel Almodóvar González, Leticia Lojo, María Jesús García De Yébenes, Francisco Javier López-Longo
The present study was undertaken to assess mortality, causes of death, and associated prognostic factors in a large cohort of patients diagnosed with idiopathic inflammatory myositis (IIM) from Spain. A retrospective longitudinal study was carried out in 467 consecutive patients with IIM, identified from 12 medical centers. Patients were classified as primary polymyositis, primary dermatomyositis (DM), overlap myositis, cancer-associated myositis (CAM), and juvenile idiopathic inflammatory myopathies. A total of 113 deaths occurred (24%) after a median follow-up time of 9...
September 2, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28866730/egfr-targeted-therapies-in-the-post-genomic-era
#9
Mary Jue Xu, Daniel E Johnson, Jennifer R Grandis
Over 90% of head and neck cancers overexpress the epidermal growth factor receptor (EGFR). In diverse tumor types, EGFR overexpression has been associated with poorer prognosis and outcomes. Therapies targeting EGFR include monoclonal antibodies, tyrosine kinase inhibitors, phosphatidylinositol 3-kinase (PI3K) inhibitors, and antisense gene therapy. Few EGFR-targeted therapeutics are approved for clinical use. The monoclonal antibody cetuximab is a Food and Drug Administration (FDA)-approved EGFR-targeted therapy, yet has exhibited modest benefit in clinical trials...
September 2, 2017: Cancer Metastasis Reviews
https://www.readbyqxmd.com/read/28838971/a-loss-of-function-splice-acceptor-variant-in-igf2-is-protective-for-type-2-diabetes
#10
Josep M Mercader, Rachel G Liao, Avery Bell, Zachary Dymek, Karol Estrada, Taru Tukiainen, Alicia Huerta-Chagoya, Hortensia Moreno-Macías, Kathleen A Jablonski, Robert L Hanson, Geoffrey A Walford, Ignasi Moran, Ling Chen, Vineeta Agarwala, María Luisa Ordoñez-Sánchez, Rosario Rodríguez-Guillen, Maribel Rodríguez-Torres, Yayoi Segura-Kato, Humberto García-Ortiz, Federico Centeno-Cruz, Francisco Barajas-Olmos, Lizz Caulkins, Sobha Puppala, Pierre Fontanillas, Amy Williams, Sílvia Bonàs-Guarch, Chris Hartl, Stephan Ripke, Katherine Tooley, Jacqueline Lane, Carlos Zerrweck, Angélica Martínez-Hernández, Emilio J Córdova, Elvia Mendoza-Caamal, Cecilia Contreras-Cubas, María E González-Villalpando, Ivette Cruz-Bautista, Liliana Muñoz-Hernández, Donaji Gómez-Velasco, Ulises Alvirde, Brian E Henderson, Lynne R Wilkens, Loic Le Marchand, Olimpia Arellano-Campos, Laura Riba, Maegan Harden, Broad Genomics Platform, Stacey Gabriel, Hanna E Abboud, Maria L Cortes, Cristina Revilla-Monsalve, Sergio Islas-Andrade, Xavier Soberon, Joanne E Curran, Christopher P Jenkinson, Ralph A DeFronzo, Donna M Lehman, Craig L Hanis, Graeme I Bell, Michael Boehnke, John Blangero, Ravindranath Duggirala, Richa Saxena, Daniel MacArthur, Jorge Ferrer, Steven A McCarroll, David Torrents, William C Knowler, Leslie J Baier, Noel Burtt, Clicerio González-Villalpando, Christopher A Haiman, Carlos A Aguilar-Salinas, Teresa Tusié-Luna, Jason Flannick, Suzanne B R Jacobs, Lorena Orozco, David Altshuler, Jose C Florez
Type 2 diabetes (T2D) affects more than 415 million people worldwide and its costs to the health care system continue to rise. To identify common or rare genetic variation with potential therapeutic implications for T2D, we analyzed and replicated genome-wide protein coding variation in a total of 8,227 individuals with T2D and 12,966 individuals without T2D of Latino descent. We identified a novel genetic variant in the IGF2 gene associated with ∼20% reduced risk for T2D. This variant, which has an allele frequency of 17% in the Mexican population but is rare in Europe, prevents splicing between IGF2 exons 1 and 2...
August 24, 2017: Diabetes
https://www.readbyqxmd.com/read/28836955/prevalence-of-hepatitis-b-in-people-living-with-hiv-aids-in-latin-america-and-the-caribbean-a-systematic-review-and-meta-analysis
#11
Fatima Mitiko Tengan, Edson Abdala, Marisa Nascimento, Wanderley Marques Bernardo, Antonio Alci Barone
BACKGROUND: Hepatitis B virus (HBV) infection is a major cause of chronic liver disease worldwide. In immunocompromised patients, the chronicity rates of HBV infection are higher, but the rates of hepatitis Be antigen (HBeAg) and HBsAg loss and seroconversion to anti-HBe and anti-HBs are lower than those in immunocompetent subjects. This study aimed to evaluate articles on the prevalence of HBsAg in people living with human immunodeficiency virus (HIV) /AIDS (PLWHA) in Latin America and the Caribbean (LAC)...
August 24, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28829889/stability-of-annual-biomass-energy-production-of-elephant-grass-pennisetum-purpureum-schum-genotypes-in-the-northern-region-of-the-rio-de-janeiro-state-brazil
#12
M S B Araújo, R F Daher, B R S Menezes, G A Gravina, V B Silva, A T Amaral Júnior, E V Rodrigues, B O Almeida, N J Ponciano
The objectives of this study were to estimate the stability of dry biomass production of elephant grass genotypes under an annual harvest regime, in soil-climatic conditions of the Northern region of the Rio de Janeiro State, Brazil, and to compare methodologies for stability analyses of Yates and Cochran (YC), Plaisted and Peterson (PP), Annicchiarico (ANN), Lin and Binns (LB), Huenh (HU), and Kang and Phan (KP). A randomized block design with 83 treatments and two replicates was adopted. Four annual harvests were performed (2012-2015) and dry matter yield (DMY, t...
August 17, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28818128/dazzling-visions-american-women-race-and-the-imperialist-origins-of-modern-nursing-in-cuba-1898-1916
#13
Laura R Prieto
No abstract text is available yet for this article.
January 1, 2018: Nursing History Review: Official Journal of the American Association for the History of Nursing
https://www.readbyqxmd.com/read/28815233/the-protective-effect-of-acerola-malpighia-emarginata-against-oxidative-damage-in-human-dermal-fibroblasts-through-the-improvement-of-antioxidant-enzyme-activity-and-mitochondrial-functionality
#14
José M Alvarez-Suarez, Francesca Giampieri, Massimiliano Gasparrini, Luca Mazzoni, Celestino Santos-Buelga, Ana M González-Paramás, Tamara Y Forbes-Hernández, Sadia Afrin, Timothy Páez-Watson, José L Quiles, Maurizio Battino
Acerola fruits (Malpighia emarginata DC.) from the central region of Cuba were analyzed to determine their chemical composition and protective capacity against oxidative damage using an in vitro human dermal fibroblast (HDFa) model. The chemical composition analyses showed a high content of vitamin C, total polyphenols, β-carotene and folates in the acerola fruit. From the HPLC-DAD/ESI-MS(n) analyses, two anthocyanins (cyanidin 3-O-rhamnoside and pelargonidin 3-O-rhamnoside), three hydroxycinnamoyl derivatives (caffeoyl hexoside, dihydrocaffeoylquinic acid and coumaroyl hexoside) and fifteen flavonols (mostly glycosylated forms of quercetin and kaempferol) were detected...
August 17, 2017: Food & Function
https://www.readbyqxmd.com/read/28814715/mast-cells-decrease-efficacy-of-anti-angiogenic-therapy-by-secreting-matrix-degrading-granzyme-b
#15
M Wroblewski, R Bauer, M Cubas Córdova, F Udonta, I Ben-Batalla, K Legler, C Hauser, J Egberts, M Janning, J Velthaus, C Schulze, K Pantel, C Bokemeyer, S Loges
Resistance towards VEGF-centered anti-angiogenic therapy still represents a substantial clinical challenge. We report here that mast cells alter the proliferative and organizational state of endothelial cells which reduces the efficacy of anti-angiogenic therapy. Consequently, absence of mast cells sensitizes tumor vessels for anti-angiogenic therapy in different tumor models. Mechanistically, anti-angiogenic therapy only initially reduces tumor vessel proliferation, however, this treatment effect was abrogated over time as a result of mast cell-mediated restimulation of angiogenesis...
August 16, 2017: Nature Communications
https://www.readbyqxmd.com/read/28807303/helminth-egg-excretion-in-horses-kept-under-tropical-conditions-prevalence-distribution-and-risk-factors
#16
J Salas-Romero, K A Gómez-Cabrera, L A Aguilera-Valle, J A Bertot, J E Salas, A Arenal, M K Nielsen
Increasing levels of anthelmintic resistance observed in equine cyathostomin parasites have led to recommendations of selective anthelmintic treatment strategies to lower the selection pressure favoring resistant populations. This principle is based on determining strongyle fecal egg counts from all herd members, and treating those exceeding a predetermined treatment cutoff. However, epidemiological information is lacking from horses kept under tropical conditions, where parasite burdens may be of a different composition and magnitude compared to those of horses kept under temperate climate conditions...
August 30, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28800498/erylosides-f8-v1-v3-and-w-w2-new-triterpene-oligoglycosides-from-the-carribean-sponge-erylus-goffrilleri
#17
Alexandr S Antonov, Anatoly I Kalinovsky, Shamil S Afiyatullov, Elena V Leshchenko, Pavel S Dmitrenok, Ekaterina A Yurchenko, Vladimir I Kalinin, Valentin A Stonik
Seven new triterpene glycosides, erylosides F8 (1), V1 (2), V2 (3), V3 (4), W (5), W1 (6) and W2 (7), were isolated from a Carribean sponge Erylus goffrilleri collected from the Carribean Sea near the Arrecife-Seco reef (Cuba). Structures of the glycosides were determined using (1)H and (13)C NMR spectroscopy, including 2D NMR procedures ((1)H-(1)H COSY, (1)H-(13)С HMBC, (1)H-(13)С HSQC and NOESY) and HR ESI mass spectrometry. Erylosides 1 and 4 have 14-carboxy-24,25-dimethyllanost-8(9)-en-3β,25-diol as aglycone whereas glycosides 2, 3, 5, 6 and 7 are 14-carboxy-24-acetoxy-24-methyllanost-8(9)-en-3β-ol glycoconjugates...
September 8, 2017: Carbohydrate Research
https://www.readbyqxmd.com/read/28800470/-210-pb-and-137-cs-as-tracers-of-recent-sedimentary-processes-in-two-water-reservoirs-in-cuba
#18
Misael Díaz-Asencio, José Antonio Corcho-Alvarado, Héctor Cartas-Aguila, Anabell Pulido-Caraballé, Carmen Betancourt, Joseph M Smoak, Elizabeth Alvarez-Padilla, Yeny Labaut-Betancourt, Carlos Alonso-Hernández, Mabel Seisdedo-Losa
Hanabanilla and Paso Bonito Reservoirs are the main fresh water sources for about half a million inhabitants in central Cuba. Prior to this investigation precise information about the losses of storage capacity was not available. Sedimentation is the dominant process leading to reduction in water storage capacity. We investigated the sedimentation process in both reservoirs by analyzing environmental radionuclides (e.g. (210)Pb, (226)Ra and (137)Cs) in sediment cores. In the shallow Paso Bonito Reservoir (mean depth of 6...
October 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28777318/unintentional-child-and-adolescent-drowning-mortality-from-2000-to-2013-in-21-countries-analysis-of-the-who-mortality-database
#19
Yue Wu, Yun Huang, David C Schwebel, Guoqing Hu
Limited research considers change over time for drowning mortality among individuals under 20 years of age, or the sub-cause (method) of those drownings. We assessed changes in under-20 drowning mortality from 2000 to 2013 among 21 countries. Age-standardized drowning mortality data were obtained through the World Health Organization (WHO) Mortality Database. Twenty of the 21 included countries experienced a reduction in under-20 drowning mortality rate between 2000 and 2013, with decreases ranging from -80 to -13%...
August 4, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28769710/the-genus-apodrosus-marshall-1922-in-cuba-coleoptera-curculionidae-entiminae-polydrusini
#20
Robert S Anderson, Guanyang Zhang
The genus Apodrosus Marshall is newly recorded for, and revised for Cuba. Nine new species are recognized as follows: Apodrosus alberti (type locality, Granma, Parque Nacional Pico Turquino), A. alternatus (type locality, Guantánamo, El Yunque), A. franklyni (type locality, Cienfuegos, Parque Nacional Pico San Juan), A. griseus (type locality, Santiago de Cuba, Siboney-Jutici Ecological Reserve), A. mensurensis (type locality, Holguin, Parque Nacional La Mensura-Piloto), A. pseudoalternatus (type locality, Matanzas, Varahicacos), A...
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