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https://www.readbyqxmd.com/read/28225546/making-travel-to-cuba-work-for-health-and-sustainable-development
#1
Conner Gorry
In 2015, a record-breaking 3.5 million visitors-1 million from Canada alone-traveled to Cuba to explore its history, culture, natural splendor, and visit family. That same year, US President Barack Obama relaxed travel restrictions, giving general authorization for a dozen categories of legal travel by US citizens and residents. As a result, US visitors to the island ballooned by 80% between January 2015 and June 2016. And the numbers keep growing: the latest data show that foreign arrivals reached 4 million in 2016...
January 2017: MEDICC Review
https://www.readbyqxmd.com/read/28225544/in-defense-of-clinical-autopsy-and-its-practice-in-cuba
#2
Alfredo D Espinosa-Brito, José Hurtado de Mendoza-Amat
There has been a notable decrease in the global practice of clinical autopsy; the rate has fallen to below 10%, even in high-income countries. This is attributed to several causes, including increased costs, overreliance on modern diagnostic techniques, cultural and religious factors, the emergence of new infectious diseases and negative attitudes on the part of doctors, even pathologists. Alternative methods to autopsy in postmortem studies have been developed based on imaging, endoscopy and biopsy (all quite expensive)...
January 2017: MEDICC Review
https://www.readbyqxmd.com/read/28225543/cuba-s-aging-and-alzheimer-longitudinal-study
#3
Juan de Jesús Llibre-Rodríguez, Adolfo Valhuerdi-Cepero, Ana M López-Medina, Lisseth Noriega-Fernández, Rutbeskia Porto-Álvarez, Milagros A Guerra-Hernández, Rodolfo I Bosch-Bayard, Tania Zayas-Llerena, Elaine Hernandez-Ulloa, Ana L Rodríguez-Blanco, Enrique Salazar-Pérez, Juan C Llibre-Guerra, Jorge J Llibre-Guerra, Beatriz Marcheco-Teruel
Aging and Alzheimer is a prospective, longitudinal cohort study involving 2944 adults aged ≥65 years from selected areas in Cuba's Havana and Matanzas Provinces. This door-to-door study, which began in 2003, includes periodic assessments of the cohort based on an interview; physical exam; anthropometric measurements; and diagnosis of dementia and its subtypes, other mental disorders, and other chronic non-communicable diseases and their risk factors. Information was gathered on sociodemographic characteristics; disability, dependency and frailty; use of health services; and characteristics of care and caregiver burden...
January 2017: MEDICC Review
https://www.readbyqxmd.com/read/28225542/historical-overview-of-leprosy-control-in-cuba
#4
Enrique Beldarraín-Chaple
INTRODUCTION Leprosy, an infectious disease caused by Mycobacterium leprae, affects the nervous system, skin, internal organs, extremities and mucous membranes. Biological, social and environmental factors influence its occurrence and transmission. The first effective treatments appeared in 1930 with the development of dapsone, a sulfone. The main components of a control and elimination strategy are early case detection and timely administration of multidrug therapy. OBJECTIVES Review the history of leprosy control in Cuba, emphasizing particularly results of the National Leprosy Control Program, its modifications and influence on leprosy control...
January 2017: MEDICC Review
https://www.readbyqxmd.com/read/28225540/antituberculosis-drug-resistance-in-pulmonary-isolates-of-mycobacterium-tuberculosis-cuba-2012-2014
#5
Dihadenys Lemus, Miguel Echemendía, Raúl Díaz, María J Llanes, Lourdes Suárez, Antonio Marrero
INTRODUCTION Systematic surveillance of antituberculosis drug resistance allows identification of multidrug-resistant and extensively drug-resistant isolates of Mycobacterium tuberculosis. Surveillance studies of antituberculosis drug resistance systematically conducted in Cuba for over 15 years have revealed low circulation of multidrug-resistant tuberculosis, under 1% in new cases. OBJECTIVE Characterize antituberculosis drug resistance in isolates of M. tuberculosis recovered from patients with pulmonary tuberculosis in Cuba in 2012-2014...
January 2017: MEDICC Review
https://www.readbyqxmd.com/read/28225539/cuba-s-family-doctor-and-nurse-teams-a-day-in-the-life
#6
Conner Gorry
Nurse Sarait Guarat has Felipe's clinical history out of the file cabinet and on Dr Martha Diaz's desk before he's even through the door. Not that Dr Díaz needs it: Having served 26 years at Consultorio (Family Doctor-and-Nurse Office) #17 on a leafy street in Havana's Vedado neighborhood, she knows each of her patients by name and their health status essentially by heart. After greeting 91-year old Felipe with the customary kiss on the cheek, Dr Díaz gets down to business, asking after his family, checking up on his diabetes and inquiring about the reason for his visit...
January 2017: MEDICC Review
https://www.readbyqxmd.com/read/28225538/may-you-live-in-interesting-times
#7
(no author information available yet)
Whether or not the so-called curse, "May you live in interesting times" is apocryphal, we have to acknowledge that we do indeed live in interesting times. It has been only three months since the October 2016 issue of MEDICC Review, but the changes since-in many directions-have been head-spinning. For starters, scientists at Roswell Park Cancer Institute have launched a clinical trial of CIMAvax, the therapeutic lung cancer vaccine developed at Cuba's Molecular Immunology Center, surely a win-win for the citizens of both countries...
January 2017: MEDICC Review
https://www.readbyqxmd.com/read/28222163/investigating-human-geographic-origins-using-dual-isotope-87sr-86sr-%C3%AE-18o-assignment-approaches
#8
Jason E Laffoon, Till F Sonnemann, Termeh Shafie, Corinne L Hofman, Ulrik Brandes, Gareth R Davies
Substantial progress in the application of multiple isotope analyses has greatly improved the ability to identify nonlocal individuals amongst archaeological populations over the past decades. More recently the development of large scale models of spatial isotopic variation (isoscapes) has contributed to improved geographic assignments of human and animal origins. Persistent challenges remain, however, in the accurate identification of individual geographic origins from skeletal isotope data in studies of human (and animal) migration and provenance...
2017: PloS One
https://www.readbyqxmd.com/read/28207967/the-synonymy-of-the-toxic-dinoflagellates-prorocentrum-mexicanum-and-p-rhathymum-and-the-description-of-p-steidingerae-sp-nov-prorocentrales-dinophyceae
#9
Fernando Gómez, Dajun Qiu, Senjie Lin
Prorocentrum mexicanum and P. rhathymum are toxicologically important dinoflagellates, but their relationship is not well defined. We investigated strains from Puerto Rico and Brazil by light and scanning electron microscopies. We provide molecular data from a strain isolated near the type locality of P. rhathymum, and the first morphological and molecular data from the South Atlantic Ocean. The rRNA gene (rDNA) sequences of the Puerto Rican and Brazilian strains were identical, and their morphologies fit the description of P...
February 16, 2017: Journal of Eukaryotic Microbiology
https://www.readbyqxmd.com/read/28201821/impact-of-cane-use-on-bone-marrow-lesion-volume-in-people-with-medial-knee-osteoarthritis-cuba-trial
#10
Ans Van Ginckel, Rana S Hinman, Tim V Wrigley, David J Hunter, Charlotte J Marshall, Luciano Melo, Sarah R F Meneses, Milena Simic, Jessica Kasza, Jeff Duryea, Jason A Wallis, Kim L Bennell
No abstract text is available yet for this article.
February 15, 2017: Physical Therapy
https://www.readbyqxmd.com/read/28191662/cannabidiol-an-alternative-therapeutic-agent-for-oral-mucositis
#11
REVIEW
L F Cuba, F G Salum, K Cherubini, M A Z Figueiredo
WHAT IS KNOWN AND OBJECTIVE: Chemo- and radiotherapy are therapeutic modalities often used in patients with malignant neoplasms. They kill tumour cells but act on healthy tissues as well, resulting in adverse effects. Oral mucositis is especially of concern, due to the morbidity that it causes. We reviewed the literature on the etiopathogenesis of oral mucositis and the activity of cannabidiol, to consider the possibility of its use for the prevention and treatment of oral mucositis. METHODS: We searched the PubMed database and selected complete articles published in English that met the inclusion criteria for the period 1998-2016...
February 12, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/28188712/-viable-allergenic-fungi-in-a-documentary-deposit-of-the-national-archive-of-cuba
#12
Alian Molina-Veloso, Sofía F Borrego-Alonso
BACKGROUND: Intense and persistent exposure to indoor-air biological agents has been associated with the appearance of allergic diseases. Archives and libraries Indoor environments in tropical countries are an important reservoir of fungal propagules. OBJECTIVE: To evaluate the degree of air pollution with allergenic fungi in a repository of frequently-manipulated documents. METHODS: Air sampling was performed by two methods: active (biocollector) and passive (sedimentation plate)...
January 2017: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://www.readbyqxmd.com/read/28187641/cryptic-within-cryptic-genetics-morphometrics-and-bioacoustics-delimitate%C3%A2-a-new-species-of-i-eleutherodactylus-i-anura-eleutherodactylidae-from-eastern-cuba
#13
Ariel Rodríguez, Álvaro Dugo-Cota, Santiago Montero-Mendieta, Alejandro Gonzalez-Voyer, Roberto Alonso Bosch, Miguel Vences, Carles Vilà
We studied the variation in genetics, bioacustics, and morphology in Eleutherodactylus glamyrus, a regionally endemic frog species restricted to high elevations in the Sierra Maestra Massif, Western Cuba that was originally described as a cryptic species hidden under the name E. auriculatus. Genetic analysis of mtDNA sequences of the 16S and cob genes identify two allopatric and strongly supported mitochondrial clades (phylogroups) which also showed no haplotype sharing in the nuclear Rag-1 gene. Bioacustic, and morphological comparisons concordantly identify these two phylogroups as independent evolutionary lineages...
January 20, 2017: Zootaxa
https://www.readbyqxmd.com/read/28183107/the-jumping-lynx-spider-i-oxyopes-i-i-salticus-i-hentz-1845-and-its-neotropical-relatives-araneae-oxyopidae
#14
Adalberto J Santos
The spider genus Oxyopes Latreille occurs throughout the world, but is insufficiently known in South America and the Caribbean. In this study, three apparently related species of this genus are reported from the region. Oxyopes salticus Hentz, 1845 is redescribed and illustrated, and extreme variation in colour pattern and in female genitalia is reported within this species. Oxyopes m-fasciatus Piza, 1938 and Oxyopes nigrolineatus Mello-Leitão, 1941 are both considered junior synonyms of O. salticus. The material examined in this study, together with information from the literature, show this species is widely distributed throughout the continental Americas and the Caribbean...
January 10, 2017: Zootaxa
https://www.readbyqxmd.com/read/28183106/systematics-and-biogeography-of-cuban-porcelain-crabs-decapoda-anomura-porcellanidae
#15
Yander L Diez, Carlos Lira
Marine crustaceans are a well-known invertebrates group in Cuban waters, but some taxa are not well catalogued and the literature about them is scattered. In this work, we present the checklist of porcelain crabs of Cuban Archipelago, including the literature registers and unpublished author's data. A key to the identification of 8 genera and 23 species of the Cuban porcelain crabs is provided. Information about the local distribution of species is presented. In addition, we analyzed the porcelain crab faunal affinities between the ecoregions of the Cuban platform, Greater Antilles islands and the Tropical Northwestern Atlantic (TNA) province...
January 10, 2017: Zootaxa
https://www.readbyqxmd.com/read/28177289/hepatitis-e-virus-in-bottlenose-dolphins-tursiops-truncatus
#16
María Caridad Montalvo Villalba, Danilo Cruz Martínez, Imran Ahmad, Licel A Rodriguez Lay, Marite Bello Corredor, Celia Guevara March, Liena Sánchez Martínez, Laima Sánchez Martínez-Campo, Shahid Jameel
Hepatitis E virus (HEV) infects several animal species that act as zoonotic reservoirs for viral transmission. Solid and liquid residues from infected animals could lead to HEV contamination of food and surface waters. Evidence of human HEV infection through ingestion of seafood (shellfish, mussels) has been reported. Dolphins generally feed on fish and squid but are able to adapt to an environment and consume whatever prey is available. Clinical signs of infected dolphins include lethargy, inappetence, behavioral aberrations and increased serum alanine aminotransferase (ALT)...
February 8, 2017: Diseases of Aquatic Organisms
https://www.readbyqxmd.com/read/28168556/complete-genome-sequences-of-two-novel-bipartite-begomoviruses-infecting-common-bean-in-cuba
#17
Lidia Chang-Sidorchuk, Heidy González-Alvarez, Jesús Navas-Castillo, Elvira Fiallo-Olivé, Yamila Martínez-Zubiaur
The common bean is a host for a large number of begomoviruses (genus Begomovirus, family Geminiviridae) in the New World. Based on the current taxonomic criteria established for the genus Begomovirus, two new members of this genus infecting common bean (Phaseolus vulgaris) in Cuba are herein reported. The cloned bipartite genomes, composed of DNA-A and DNA-B, showed the typical organization of the New World begomoviruses. We propose the names common bean severe mosaic virus and common bean mottle virus for the new begomovirus species...
February 6, 2017: Archives of Virology
https://www.readbyqxmd.com/read/28162975/comprehensive-molecular-characterization-of-pheochromocytoma-and-paraganglioma
#18
Lauren Fishbein, Ignaty Leshchiner, Vonn Walter, Ludmila Danilova, A Gordon Robertson, Amy R Johnson, Tara M Lichtenberg, Bradley A Murray, Hans K Ghayee, Tobias Else, Shiyun Ling, Stuart R Jefferys, Aguirre A de Cubas, Brandon Wenz, Esther Korpershoek, Antonio L Amelio, Liza Makowski, W Kimryn Rathmell, Anne-Paule Gimenez-Roqueplo, Thomas J Giordano, Sylvia L Asa, Arthur S Tischler, Karel Pacak, Katherine L Nathanson, Matthew D Wilkerson
We report a comprehensive molecular characterization of pheochromocytomas and paragangliomas (PCCs/PGLs), a rare tumor type. Multi-platform integration revealed that PCCs/PGLs are driven by diverse alterations affecting multiple genes and pathways. Pathogenic germline mutations occurred in eight PCC/PGL susceptibility genes. We identified CSDE1 as a somatically mutated driver gene, complementing four known drivers (HRAS, RET, EPAS1, and NF1). We also discovered fusion genes in PCCs/PGLs, involving MAML3, BRAF, NGFR, and NF1...
February 2, 2017: Cancer Cell
https://www.readbyqxmd.com/read/28138558/circulating-cxcr5-cxcr3-pd-1-lo-tfh-like-cells-in-hiv-1-controllers-with-neutralizing-antibody-breadth
#19
Enrique Martin-Gayo, Jacqueline Cronin, Taylor Hickman, Zhengyu Ouyang, Madelene Lindqvist, Kellie E Kolb, Julian Schulze Zur Wiesch, Rafael Cubas, Filippos Porichis, Alex K Shalek, Jan van Lunzen, Elias K Haddad, Bruce D Walker, Daniel E Kaufmann, Mathias Lichterfeld, Xu G Yu
HIV-1-specific broadly neutralizing antibodies (bnAbs) typically develop in individuals with continuous high-level viral replication and increased immune activation, conditions that cannot be reproduced during prophylactic immunization. Understanding mechanisms supporting bnAb development in the absence of high-level viremia may be important for designing bnAb-inducing immunogens. Here, we show that the breadth of neutralizing antibody responses in HIV-1 controllers was associated with a relative enrichment of circulating CXCR5(+)CXCR3(+)PD-1(lo) CD4(+) T cells...
January 26, 2017: JCI Insight
https://www.readbyqxmd.com/read/28120949/extent-of-night-warming-and-spatially-heterogeneous-cloudiness-differentiate-temporal-trend-of-greenness-in-mountainous-tropics-in-the-new-century
#20
Mei Yu, Qiong Gao, Chunxiao Gao, Chao Wang
Tropical forests have essential functions in global C dynamics but vulnerable to changes in land cover land use (LCLUC) and climate. The tropics of Caribbean are experiencing warming and drying climate and diverse LCLUC. However, large-scale studies to detect long-term trends of C and mechanisms behind are still rare. Using MODIS Enhanced Vegetation Index (EVI), we investigated greenness trend in the Greater Antilles Caribbean during 2000-2015, and analyzed trend of vegetation patches without LCLUC to give prominence to climate impacts...
January 25, 2017: Scientific Reports
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