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Breast arterial calcification

Qin Li, Songtao Liu, Kyle J Myers, Marios A Gavrielides, Rongping Zeng, Berkman Sahiner, Nicholas Petrick
RATIONALE AND OBJECTIVES: Different computed tomography imaging protocols and patient characteristics can impact the accuracy and precision of the calcium score and may lead to inconsistent patient treatment recommendations. The aim of this work was to determine the impact of reconstruction algorithm and gender characteristics on coronary artery calcium scoring based on a phantom study using computed tomography. MATERIALS AND METHODS: Four synthetic heart vessels with vessel diameters corresponding to female and male left main and left circumflex arteries containing calcification-mimicking materials (200-1000 HU) were inserted into a thorax phantom and were scanned with and without female breast plates (male and female phantoms, respectively)...
September 22, 2016: Academic Radiology
Kadihan Yalçin Şafak, Ayşegül Eratalay, Ebru Dülger İliş, Neslihan Umarusman Tanju
BACKGROUND/AIM: We aimed to detect the incidence of breast arterial calcification (BAC) in patients that underwent mammography and to reveal the relationship of BAC with cardiovascular diseases, cardiovascular risk factors, parity, and breastfeeding. MATERIALS AND METHODS: A total of 1195 female patients were included in this study. Cases that were positive for BAC during mammography were recorded. The relationship of BAC with age, body mass index, parity, breastfeeding, menopause, smoking, alcohol consumption, oral contraceptive use, hormone replacement therapy, and histories of hypertension (HT), diabetes mellitus (DM), coronary artery disease (CAD), and cerebral vascular diseases were investigated...
2016: Turkish Journal of Medical Sciences
Marco Zuin, Gianluca Rigatelli, Fiorenzo Scaranello, Sergio Giuseppe Ribecco, Claudio Picariello, Giovanni Zuliani, Giuseppe Faggian, Pietro Zonzin, Loris Roncon
No abstract text is available yet for this article.
October 1, 2016: International Journal of Cardiology
Tamuna Chadashvili, Diana Litmanovich, Ferris Hall, Priscilla J Slanetz
PURPOSE: To determine whether breast arterial calcifications (BAC) seen on mammography correlates with coronary artery calcium score on coronary CT as it may serve as a potential marker for increased risk of developing symptomatic coronary artery disease (CAD). MATERIALS AND METHODS: Retrospective review of the imaging database at our institution identified 145 female patients who underwent coronary CT within a year of screening or diagnostic mammography. The coronary calcium score on CT was calculated by multiplying area of calcification by weighted value assigned to its highest Hounsfield unit and summed for all lesions and expressed as Agaston score...
June 2016: European Journal of Radiology
Khurram Nasir, John W McEvoy
No abstract text is available yet for this article.
April 2016: JACC. Cardiovascular Imaging
Laurie Margolies, Mary Salvatore, Harvey S Hecht, Sean Kotkin, Rowena Yip, Usman Baber, Vivian Bishay, Jagat Narula, David Yankelevitz, Claudia Henschke
OBJECTIVES: This study sought to determine if breast arterial calcification (BAC) on digital mammography predicts coronary artery calcification (CAC). BACKGROUND: BAC is frequently noted but the quantitative relationships to CAC and risk factors are unknown. METHODS: A total of 292 women with digital mammography and nongated computed tomography was evaluated. BAC was quantitatively evaluated (0 to 12) and CAC was measured on computed tomography using a 0 to 12 score; they were correlated with each other and the Framingham Risk Score (FRS) and the 2013 Cholesterol Guidelines Pooled Cohort Equations (PCE)...
April 2016: JACC. Cardiovascular Imaging
Jan-Jurre Mordang, Albert Gubern-Mérida, Gerard den Heeten, Nico Karssemeijer
PURPOSE: In the past decades, computer-aided detection (CADe) systems have been developed to aid screening radiologists in the detection of malignant microcalcifications. These systems are useful to avoid perceptual oversights and can increase the radiologists' detection rate. However, due to the high number of false positives marked by these CADe systems, they are not yet suitable as an independent reader. Breast arterial calcifications (BACs) are one of the most frequent false positives marked by CADe systems...
April 2016: Medical Physics
N Ali-Tatar Chentir, M Korabi, M T Chentir
OBJECTIFS: Irradiation of the heart in patients with breast cancer increases the risk of the so-called "radiation-induced heart disease" (RIHD). Among risk factors of RIHD, overweight, hypertension and diabetes mellitus take a major place. To describe a clinical case of an obese hypertensive diabetes mellitus woman with breast cancer since the begining of her radiotherapy until heart failure on the basis of the report from the European Association of Cardiovascular Imaging consensus for evaluation of cardiovascular complications of radiotherapy in adults...
December 2015: Annales de Cardiologie et D'angéiologie
Kum Hyun Han, W Charles O'Neill
BACKGROUND: Matrix Gla protein is a vitamin K-dependent inhibitor of vascular calcification. Warfarin use is associated with increased breast arterial calcification, but whether this is reflective of other arteries or occurs in men is unclear. In this study, the prevalence of calcification in peripheral arteries was compared in patients with and without warfarin therapy. METHODS AND RESULTS: This retrospective matched cohort study assessed 430 patients with radiographs performed during or after warfarin therapy who were identified by a computerized search of medical records...
January 2016: Journal of the American Heart Association
Athanassios Zissimopoulos, Lukia Baloka, Eleni Nagorni, Evangelos Karathanos, Antonios Tsartsarakis, Vasiliki Apostolidou, Andina Thomaidou, Gregory Tripsianis
OBJECTIVE: Fetuin-A is an acidic glycoprotein produced in the liver, as an inhibitor for cysteine protease. Its gene is founded in chromosome 3 (3q27). It is involved in various physiological and pathological conditions. These include vascular decalcification, bone metabolism, insulin resistance, protease function control, neurological illnesses and multiplication of breast cancer cells. Vascular calcifications predict cardiovascular disease which can be a major cause of death. So, fetuin-A is a potent circulating calcification inhibitor...
September 2015: Hellenic Journal of Nuclear Medicine
Matthew C Whitlock, Joseph Yeboah, Gregory L Burke, Haiying Chen, Heidi D Klepin, W Gregory Hundley
BACKGROUND: Although cancer and its corresponding therapies are associated with increased ischemic heart disease, the temporal relationship between cancer and the development of coronary artery calcium (CAC), a marker of subclinical atherosclerosis, is unknown. METHODS AND RESULTS: Among 3122 men and women free of cardiovascular disease and cancer in the Multi-Ethnic Study of Atherosclerosis trial, CAC scoring was performed at baseline (2000-2002) and at follow-up (2010-2012)...
November 9, 2015: Journal of the American Heart Association
Domnique Newallo, Felix G Meinel, U Joseph Schoepf, Stefan Baumann, Carlo N De Cecco, Rebecca J Leddy, Rozemarijn Vliegenthart, Helge Möllmann, Christian W Hamm, Pamela B Morris, Matthias Renker
OBJECTIVE: Accumulating data on predominantly Caucasian women suggests an association between breast arterial calcification (BAC) and coronary artery disease (CAD). We sought to comprehensively examine the correlation between mammographic BAC and CAD endpoints detected by cardiac computed tomography (CCT) in African American (AA) women. METHODS: Consecutive AA women who underwent digital screening mammography and CCT were identified. In blinded fashion, mammographic and CCT studies were reviewed...
September 2015: Atherosclerosis
Nesrin Atci, Eda Elverici, Raziye Keskin Kurt, Derya Ozen, Ebru Unlu, Levent Araz
OBJECTIVE: Breast arterial calcification (BAC), medial calcific sclerosis of small to medium-sized muscular arteries, is a benign finding of mammographic evaluation. Previous studies have shown the relationships between BAC and systemic disorders such as cardiovascular disease, diabetes mellitus and hypertension. The aim of this study was to determine the association between reduced bone mineral density and BAC. METHODS: The study population consisted of 567 women who had both mammography and bone mineral density evaluation...
March 2015: Pakistan Journal of Medical Sciences Quarterly
Leila Mostafavi, Wanda Marfori, Cesar Arellano, Alessia Tognolini, William Speier, Ali Adibi, Stefan G Ruehm
To assess the correlation between breast arterial calcifications (BAC) on digital mammography and the extent of coronary artery disease (CAD) diagnosed with dual source coronary computed tomography angiography (CTA) in a population of women both symptomatic and asymptomatic for coronary artery disease. 100 consecutive women (aged 34 - 86 years) who underwent both coronary CTA and digital mammography were included in the study. Health records were reviewed to determine the presence of cardiovascular risk factors such as hypertension, hyperlipidemia, diabetes mellitus, and smoking...
2015: PloS One
David H Barlow
No abstract text is available yet for this article.
February 2015: Menopause: the Journal of the North American Menopause Society
Eva J E Hendriks, Pim A de Jong, Yolanda van der Graaf, Willem P Th M Mali, Yvonne T van der Schouw, Joline W J Beulens
OBJECTIVE: Breast arterial calcifications (BAC), regularly observed at mammography, are medial calcifications and as such an expression of arteriosclerosis. Our objective was to evaluate and summarize the available evidence on the associations of BAC with cardiovascular risk factors and cardiovascular risk. METHODS: A systematic literature review and meta-analysis were conducted. Embase and PubMed databases were searched. After critical appraisal, odds ratios were extracted from studies of moderate or good quality that examined risk factors for BAC or associations of BAC with cardiovascular disease...
March 2015: Atherosclerosis
Ozlem Soran, John A Vargo, Ahmet Veysel Polat, Atilla Soran, Jules Sumkin, Sushil Beriwal
BACKGROUND: Recent studies have suggested an association between radiation therapy (RT) of the left breast and increased incidence of coronary artery disease. However, the increased sparing afforded with modern RT may decrease long-term cardiac risk. The aims of our study were to evaluate the association between the RT and cardiac events in breast cancer patients who underwent contemporary RT and to examine whether breast arterial calcification (BAC) seen on mammogram predicts for cardiac events...
December 2014: Journal of Women's Health
Ekamol Tantisattamo, Kum Hyun Han, W Charles O'Neill
OBJECTIVE: Matrix gla protein is a vitamin K-dependent inhibitor of medial arterial calcification whose synthesis and activity are blocked by warfarin. Warfarin induces arterial calcification in experimental models, but whether this occurs in humans is unclear. This was addressed by examining breast arterial calcification, which is exclusively medial and easily identified on mammograms. APPROACH AND RESULTS: Screening mammograms from women with current, past, or future warfarin use were examined for the presence of arterial calcification and compared with mammograms obtained in untreated women matched for age and diabetes mellitus...
January 2015: Arteriosclerosis, Thrombosis, and Vascular Biology
Orlando José de Almeida, Mariana Meira Vieira, Beatriz Regina Alvares, Aarão Mendes Pinto Neto, Ciro Jabur Pimenta
PURPOSE: To analyze associations between mammographic arterial mammary calcifications in menopausal women and risk factors for cardiovascular disease. METHODS: This was a cross-sectional retrospective study, in which we analyzed the mammograms and medical records of 197 patients treated between 2004 and 2005. Study variables were: breast arterial calcifications, stroke, acute coronary syndrome, age, obesity, diabetes mellitus, smoking, and hypertension. For statistical analysis, we used the Mann-Whitney, χ2 and Cochran-Armitage tests, and also evaluated the prevalence ratios between these variables and mammary artery calcifications...
July 2014: Revista Brasileira de Ginecologia e Obstetrícia
Xuezhi Jiang, Maureen Clark, Rupali K Singh, Alex Juhn, Peter F Schnatz
OBJECTIVE: We conducted a meta-analysis of the current literature to deduce the strength of association between breast arterial calcification (BAC) and coronary artery disease (CAD) and/or stroke. METHODS: PubMed, Google Scholar,, and Ovid were searched for English-language literature up to August 2013 using the terms "breast arterial calcification," "breast vascular calcification," "coronary artery disease," "coronary heart disease," "cardiovascular disease," "abnormal coronary angiography," and "stroke...
February 2015: Menopause: the Journal of the North American Menopause Society
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