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Breast arterial calcification

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https://www.readbyqxmd.com/read/29750180/reporting-of-coronary-artery-calcification-on-chest-ct-studies-in-breast-cancer-patients-at-high-risk-of-cancer-therapy-related-cardiac-events
#1
William J Phillips, Christopher Johnson, Angeline Law, Michele Turek, Alex R Small, Joao R Inacio, Susan Dent, Terrence Ruddy, Rob S Beanlands, Benjamin J W Chow, Gary R Small
Background: The identification of coronary artery calcification (CAC) detected coincidentally on chest CT exams could assist in cardiovascular risk assessment but may not be reported consistently on clinical studies. Cardiovascular risk factor stratification is important to predict short term cardiac events during cancer therapy and long term cardiac event free survival in cancer patients. We sought to determine the prevalence of CAC and clinical reporting rates in a cohort of cancer patients at high risk of cancer therapy related cardiac events...
March 2018: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/29713021/risk-of-cardiomyopathy-and-cardiac-arrhythmias-in-patients-with-nonalcoholic-fatty-liver-disease
#2
REVIEW
Quentin M Anstee, Alessandro Mantovani, Herbert Tilg, Giovanni Targher
Nonalcoholic fatty liver disease (NAFLD) is a common, progressive liver disease that affects up to one-quarter of the adult population worldwide. The clinical and economic burden of NAFLD is mainly due to liver-related morbidity and mortality (nonalcoholic steatohepatitis, cirrhosis or hepatocellular carcinoma) and an increased risk of developing fatal and nonfatal cardiovascular disease, chronic kidney disease and certain types of extrahepatic cancers (for example, colorectal cancer and breast cancer). Additionally, there is now accumulating evidence that NAFLD adversely affects not only the coronary arteries (promoting accelerated coronary atherosclerosis) but also all other anatomical structures of the heart, conferring an increased risk of cardiomyopathy (mainly left ventricular diastolic dysfunction and hypertrophy, leading to the development of congestive heart failure), cardiac valvular calcification (mainly aortic-valve sclerosis), cardiac arrhythmias (mainly atrial fibrillation) and some cardiac conduction defects...
April 30, 2018: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29703498/automatic-quantification-of-calcifications-in-the-coronary-arteries-and-thoracic-aorta-on-radiotherapy-planning-ct-scans-of-western-and-asian-breast-cancer-patients
#3
Sofie A M Gernaat, Sanne G M van Velzen, Vicky Koh, Marleen J Emaus, Ivana Išgum, Nikolas Lessmann, Shinta Moes, Anouk Jacobson, Poey W Tan, Diederick E Grobbee, Desiree H J van den Bongard, Johann I Tang, Helena M Verkooijen
PURPOSE: This study automatically quantified calcifications in coronary arteries (CAC) and thoracic aorta (TAC) on breast planning computed tomography (CT) scans and assessed its reproducibility compared to manual scoring. MATERIAL AND METHODS: Dutch (n = 1199) and Singaporean (n = 1090) breast cancer patients with radiotherapy planning CT scan were included. CAC and TAC were automatically scored using deep learning algorithm. CVD risk categories were based on Agatson CAC: 0, 1-10, 11-100, 101-400 and >400...
April 24, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29648938/novel-assessment-tool-for-coronary-artery-disease-severity-during-screening-mammography
#4
Dušan Ružičić, Milan Dobrić, Mira Vuković, Dragan Hrnčić, Slavica Đorđević, Milijana Ružičić, Srđan Aleksandrić, Ana Đorđević-Dikić, Branko Beleslin
Breast arterial calcifications (BACs) are common findings on mammography which are associated with an increased risk of the coronary artery disease (CAD). Our aim in the current study was to design measurement instruments of CAD prediction, with or without BACs, and its discriminatory validity in the diagnosis of CAD (expressed by Syntax score) in women. This was observational, prospective study in the women cohort which underwent mammography and angiography. In this study we have demonstrated that the total 'The Breast Arterial Calcification and Coronary Artery Disease Scale' (BACCADS) was good additional diagnostic tool for detection of patients with severe CAD...
April 12, 2018: Health Care for Women International
https://www.readbyqxmd.com/read/29246501/multiethnic-study-of-breast-arterial-calcium-gradation-and-cardiovascular-disease-cohort-recruitment-and-baseline-characteristics
#5
Carlos Iribarren, Gabriela Sanchez, Gail Husson, Tory Levine-Hall, Charles Quesenberry, Danny L Sam, Joetta Maier, Rakesh S Chaudhary, Minal Patel, Bahman Sadeghi, Hanna Javan, Hyo-Min Cho, Huanjun Ding, Sabee Molloi
PURPOSE: MultIethNic Study of BrEast ARterial Calcium Gradation and CardioVAscular Disease (MINERVA) was designed to answer the question of whether a novel continuous breast arterial calcification (BAC) mass score improves cardiovascular risk stratification among asymptomatic postmenopausal women. This article describes recruitment and baseline characteristics. METHODS: MINERVA is a multiethnic longitudinal cohort study. The phenotype data include BAC mass by densitometry applied to digital mammograms, sociodemographic factors, self-reported medical history, medications, parental history, reproductive history, smoking, alcohol consumption, physical activity, anthropometry, ankle-brachial index, blood pressure, laboratory panel, breast volumes, cognitive function, bioelectrical impedance, habitual diet, dietary supplements, sleep, psychosocial factors, and sun exposure...
January 2018: Annals of Epidemiology
https://www.readbyqxmd.com/read/29127877/breast-arterial-calcification-on-screening-mammography-can-predict-significant-coronary-artery-disease-in-women
#6
Brendan S Kelly, Emer ScanlON, Helen Heneghan, Ciaran E Redmond, Gerard M Healy, Enda Mc Dermott, Eric J Heffernan, Ruth Prichard, Sorcha Mc Nally
INTRODUCTION: Breast Arterial Calcification (BAC) on digital mammography has been associated with an increased risk of Coronary Artery Disease (CAD). We aimed to investigate the association of BAC with findings on Coronary Computed Tomography Angiography (CCTA) within a cohort of women from the national breast screening program. METHODS: Symptomatic women (chest pain) aged between 50 and 65 who underwent a CCTA and who also had a screening mammography between 2014 and 2015 were recorded...
November 3, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/29118884/breast-arterial-calcifications-on-mammography-do-not-predict-myocardial-ischemia-on-myocardial-perfusion-single-photon-emission-computed-tomography
#7
Ahmed Fathala, Salma Salem, Fahad Alanazi, Deema Abunayyan, Abdelmoneim M Eldali, Abdulaziz Alsugair
Background: The aim of this study was to determine if breast arterial calcification (BAC) on mammography predicts myocardial ischemia (MI) on stress myocardial perfusion single-photon emission computed tomography (MPS). BAC is a type of medial artery calcification that can be seen incidentally on mammography, but the relationship between coronary artery calcification and MI on MPS is yet unknown. Methods: A total of 435 consecutive women underwent mammography and stress MPS within 1 year of each other...
October 2017: Cardiology Research
https://www.readbyqxmd.com/read/28953214/clinical-trials-in-menopause
#8
Kathryn I Marko, James A Simon
OBJECTIVE: Clinical trials in menopause have undergone much scrutiny over the years. This has led to significant shifts in the treatment of symptomatic menopause and a substantial impact on women. We aim to delineate the key studies contributing to this controversy and highlight new directions specifically related to menopausal hormone therapy (HT) and vascular disease risk. METHODS: We performed a search of sentinel studies delineating the risks and benefits of HT in otherwise healthy postmenopausal women...
February 2018: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28941758/dark-field-imaging-in-coronary-atherosclerosis
#9
Holger Hetterich, Nicole Webber, Marian Willner, Julia Herzen, Lorenz Birnbacher, Sigrid Auweter, Ulrich Schüller, Fabian Bamberg, Susan Notohamiprodjo, Harald Bartsch, Johannes Wolf, Mathias Marschner, Franz Pfeiffer, Maximilian Reiser, Tobias Saam
OBJECTIVES: Dark-field imaging based on small angle X-ray scattering has been shown to be highly sensitive for microcalcifications, e.g. in breast tissue. We hypothesized (i) that high signal areas in dark-field imaging of atherosclerotic plaque are associated with microcalcifications and (ii) that dark-field imaging is more sensitive for microcalcifications than attenuation-based imaging. METHODS: Fifteen coronary artery specimens were examined at an experimental set-up consisting of X-ray tube (40kV), grating-interferometer and detector...
September 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28876631/breast-arterial-calcification-on-mammography-a-proposed-tool-to-identify-women-at-risk-for-cardiovascular-disease
#10
F Mohammed
BACKGROUND: Calcification of breast arteries, observed on mammography, has been shown to have a positive association with cardiovascular disease and its risk factors, with literature suggesting that its presence should alert the clinician to underlying subclinical disease. METHOD: Of the women referred for mammograms between 1 January 2011 and 31 December 2011, 167 women over the age of 50 years, were included in the study. A retrospective review of the mammograms was done to determine the prevalence of breast arterial calcifications...
June 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28540199/role-of-different-imaging-modalities-of-vascular-calcification-in-predicting-outcomes-in-chronic-kidney-disease
#11
REVIEW
Sinee Disthabanchong, Sarinya Boongird
Vascular calcification (VC) is common among patients with chronic kidney disease (CKD). The severity of VC is associated with increased risk of cardiovascular events and mortality. Risk factors for VC include traditional cardiovascular risk factors as well as CKD-related risk factors such as increased calcium and phosphate load. VC is observed in arteries of all sizes from small arterioles to aorta, both in the intima and the media of arterial wall. Several imaging techniques have been utilized in the evaluation of the extent and the severity of VC...
May 6, 2017: World Journal of Nephrology
https://www.readbyqxmd.com/read/28516070/bone-density-in-postmenopausal-women-with-or-without-breast-arterial-calcification
#12
Atoosa Adibi, Farnaz Rabani, Silva Hovsepian
BACKGROUND: Identification of osteoporosis in women in order to prevent its related morbidity and mortality is considered a priority. Routine mammography is performed on all menopausal women as a screening tool. Determination of the relation between breast arterial calcification (BAC) on mammography and the bone density of this high-risk population could help us to determine those with osteoporosis. The aim of this study was to investigate the mentioned probable relation between BAC and osteoporosis...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28444996/breast-arterial-calcification-association-with-coronary-artery-calcium-scoring-and-implications-for-cardiovascular-risk-assessment-in-women
#13
REVIEW
Angela J Ryan, Andrew D Choi, Brian G Choi, Jannet F Lewis
Breast arterial calcification (BAC) is a type of medial artery calcification that can be seen incidentally on mammography. Studies have suggested association of BAC with cardiovascular risk factors, coronary artery disease (CAD), and cardiovascular morbidity and mortality. Recently published studies have also suggested a modest correlation of BAC with coronary artery calcium (CAC) scoring. Roughly 40 million mammograms are already performed annually in the United States with overlap in patients that undergo CAD screening via CAC scoring...
September 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28428650/routine-mammography-an-opportunity-for-the-diagnosis-of-chronic-degenerative-diseases-a-cross-sectional-study
#14
Flávio Augusto Teixeira Ronzani, Filomena Maria Kirchmaier, Nathália Mussi Monteze, Edson José de Carvalho Magacho, Marcus Gomes Bastos, Natália Maria da Silva Fernandes
OBJECTIVE: The aim of this study was to evaluate breast arterial calcification (BAC) detected on routine mammography, analyzing its association with chronic degenerative disease. MATERIALS AND METHODS: This was a cross-sectional study involving women treated at a specialized outpatient clinic for high-risk hypertension, diabetes, or chronic kidney disease, as well as volunteers who participated in a study to validate a method of screening for occult renal disease...
March 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28270321/breast-arterial-calcification-for-personalized-cardiovascular-risk-assessment-where-do-we-stand
#15
EDITORIAL
Miguel Cainzos-Achirica, Rajesh Tota-Maharaj
No abstract text is available yet for this article.
April 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28216252/calcification-of-the-splenic-iliac-and-breast-arteries-and-risk-of-all-cause-and-cardiovascular-mortality
#16
COMPARATIVE STUDY
Eva J E Hendriks, Joline W J Beulens, Pim A de Jong, Yvonne T van der Schouw, Wei-Ning Sun, C Michael Wright, Michael H Criqui, Matthew A Allison, Joachim H Ix
BACKGROUND AND AIMS: CVD risks associated with coronary artery calcification (CAC) and aortic calcification (AC) are well known, but less is known about other calcified arteries. We aimed to assess the associations of arterial calcification in the breast, splenic, and internal and external iliac arteries with CVD risk factors and mortality. METHODS: We conducted a case-cohort study nested in a cohort of 5196 individuals who self-referred or were referred by a health care provider for whole body computed tomography (CT), including a random subcohort (n = 395) and total and CVD mortality cases (n = 298 and n = 90), who died during a median follow-up of 9...
April 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28153985/breast-arterial-calcification-expanding-the-reach-of-cardiovascular-prevention
#17
Tamar S Polonsky, Philip Greenland
No abstract text is available yet for this article.
February 7, 2017: Circulation
https://www.readbyqxmd.com/read/28113340/detecting-cardiovascular-disease-from-mammograms-with-deep-learning
#18
Juan Wang, Huanjun Ding, Fatemeh Azamian Bidgoli, Brian Zhou, Carlos Iribarren, Sabee Molloi, Pierre Baldi
Coronary artery disease is a major cause of death in women. Breast arterial calcifications (BACs), detected inmammograms, can be useful riskmarkers associated with the disease. We investigate the feasibility of automated and accurate detection ofBACsinmammograms for risk assessment of coronary artery disease. We develop a 12-layer convolutional neural network to discriminate BAC from non-BAC and apply a pixelwise, patch-based procedure for BAC detection. To assess the performance of the system, we conduct a reader study to provide ground-truth information using the consensus of human expert radiologists...
May 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/27665673/impact-of-reconstruction-algorithms-and-gender-associated-anatomy-on-coronary-calcium-scoring-with-ct-an-anthropomorphic-phantom-study
#19
Qin Li, Songtao Liu, Kyle J Myers, Marios A Gavrielides, Rongping Zeng, Berkman Sahiner, Nicholas Petrick
RATIONALE AND OBJECTIVES: Different computed tomography imaging protocols and patient characteristics can impact the accuracy and precision of the calcium score and may lead to inconsistent patient treatment recommendations. The aim of this work was to determine the impact of reconstruction algorithm and gender characteristics on coronary artery calcium scoring based on a phantom study using computed tomography. MATERIALS AND METHODS: Four synthetic heart vessels with vessel diameters corresponding to female and male left main and left circumflex arteries containing calcification-mimicking materials (200-1000 HU) were inserted into a thorax phantom and were scanned with and without female breast plates (male and female phantoms, respectively)...
December 2016: Academic Radiology
https://www.readbyqxmd.com/read/27513236/the-relationship-of-breast-arterial-calcification-detected-in-mammographic-examinations-with-cardiovascular-diseases-cardiovascular-risk-factors-parity-and-breastfeeding
#20
Kadihan Yalçin Şafak, Ayşegül Eratalay, Ebru Dülger İliş, Neslihan Umarusman Tanju
BACKGROUND/AIM: We aimed to detect the incidence of breast arterial calcification (BAC) in patients that underwent mammography and to reveal the relationship of BAC with cardiovascular diseases, cardiovascular risk factors, parity, and breastfeeding. MATERIALS AND METHODS: A total of 1195 female patients were included in this study. Cases that were positive for BAC during mammography were recorded. The relationship of BAC with age, body mass index, parity, breastfeeding, menopause, smoking, alcohol consumption, oral contraceptive use, hormone replacement therapy, and histories of hypertension (HT), diabetes mellitus (DM), coronary artery disease (CAD), and cerebral vascular diseases were investigated...
2016: Turkish Journal of Medical Sciences
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