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Functional abdominal pain

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https://www.readbyqxmd.com/read/28228103/disease-manifestations-and-burden-of-illness-in-patients-with-acid-sphingomyelinase-deficiency-asmd
#1
REVIEW
Margaret M McGovern, Ruzan Avetisyan, Bernd-Jan Sanson, Olivier Lidove
Acid sphingomyelinase deficiency (ASMD), a rare lysosomal storage disease, is an autosomal recessive genetic disorder caused by different SMPD1 mutations. Historically, ASMD has been classified as Niemann-Pick disease (NPD) types A (NPD A) and B (NPD B). NPD A is associated with a uniformly devastating disease course, with rapidly progressing psychomotor degeneration, leading to death typically by the age of 3 years, most often from respiratory failure. In contrast, the clinical phenotype and life expectancy of patients with NPD B may vary widely...
February 23, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28225716/divergent-functions-of-the-left-and-right-central-amygdala-in-visceral-nociception
#2
Katelyn E Sadler, Neal A McQuaid, Abigail C Cox, Marissa N Behun, Allison M Trouten, Benedict J Kolber
The left and right central amygdala (CeA) are limbic regions involved in somatic and visceral pain processing. These two nuclei are asymmetrically involved in somatic pain modulation; pain-like responses on both sides of the body are preferentially driven by the right CeA, and in a reciprocal fashion, nociceptive somatic stimuli on both sides of the body predominantly alter molecular and physiological activity in the right CeA. Unknown however, is whether this lateralization also exists in visceral pain processing, and furthermore, what function the left CeA has in modulating nociceptive information...
December 29, 2016: Pain
https://www.readbyqxmd.com/read/28221193/normal-gallbladder-ejection-fraction-occurring-unexpectedly-obviates-need-for-sincalide-stimulation
#3
Samir Hadi, Mark Tulchinsky
A 25-year-old man was referred for chronic right upper quadrant abdominal pain for hepatobiliary scintigraphy to evaluate the gallbladder (GB) function. An unexpected GB contraction with ejection fraction (EF) of 90% was observed during the first hour of baseline imaging. Subsequent stimulation with sincalide produced GB EF of 99%. A similar case previously reported also showed normal unexpected GB EF that predicted similar post-sincalide GB EF. These examples support what should be evident: A normal unexpected GB EF is a sufficient evidence for a normal GB function and should obviate need for sincalide stimulation...
February 17, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28216917/uterine-conserving-surgery-in-a-case-of-cervicovaginal-agenesis-with-unicornuate-uterus
#4
Vineet Mishra, Suwa Ram Saini, Sakshi Nanda, Sumesh Choudhary, Priyankur Roy, Tanvir Singh
The presence of cervicovaginal agenesis with unicornuate uterus is a very rare mullerian anomaly. Its true incidence is still unknown. The presence of functioning unicornuate uterus poses a great challenge for a gynecologist because a successful repair could restore normal menses and may preserve a patient's fertility. Hence, we report a case of 16-year-old unmarried female who presented with chief complaints of primary amenorrhea with cyclical lower abdominal pain. On clinical and radiological evaluation, she was diagnosed with complete cervicovaginal agenesis with right unicornuate uterus (hematometra and hematosalpinx)...
October 2016: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/28215390/osteopathic-management-of-chronic-constipation-in-women-patients-results-of-a-pilot-study
#5
Aurélie Belvaux, Michel Bouchoucha, Robert Benamouzig
BACKGROUND AND AIMS: Constipation is a common problem in western countries. The aim of this pilot study was to determine the effectiveness of osteopathic manipulative treatment (OMT) for the treatment of constipated women with functional constipation (FC) or defeation disorders (DD). METHODS: Twenty-one constipated females referred to a tertiary center were recruited. A course of OMT, weekly for four weeks, was given. Clinical questionnaire, Bristol stool form scale and patients' subjective perception of constipation, bloating and abdominal pain, were recorded...
February 15, 2017: Clinics and Research in Hepatology and Gastroenterology
https://www.readbyqxmd.com/read/28212279/do-mothers-benefit-from-a-child-focused-cognitive-behavioral-treatment-cbt-for-childhood-functional-abdominal-pain-a-randomized-controlled-pilot-trial
#6
Claudia Calvano, Martina Groß, Petra Warschburger
While the efficacy of cognitive-behavioral treatment (CBT) approaches for childhood functional abdominal pain (FAP) is well-established for child outcomes, only a few studies have reported on parent-specific outcomes. This randomized controlled pilot trial analyzed effects of a group CBT on maternal variables (i.e., pain-related behavior, worries and self-efficacy, as well as general psychosocial strain). Methods: The sample constituted of 15 mothers in the intervention group (IG) and 14 mothers in the waitlist control group (WLC)...
February 15, 2017: Children
https://www.readbyqxmd.com/read/28212261/passage-of-gallstones-into-common-bile-duct-during-laparoscopic-cholecystectomy-is-it-surgeon-s-responsibility
#7
Mohammed Bani Hani, Abdel Rahman Al Manasra, Haitham Qandeel
PURPOSE: Gallstones patients without preoperative history of jaundice, deranged liver function tests, or dilated bile ducts (BD) are unlikely to have BD stones. However, some of these patients in our series underwent endoscopic stone(s) removal after laparoscopic cholecystectomy (LC). We aim to find the incidence, possible intraoperative risk factors, and if the Surgeon can be blamed for this event. MATERIALS AND METHODS: We studied LC cases over 12-year period at our university hospital and identified patients who did not have preoperative risk factors for BD stones but developed postoperative jaundice and/or persistent abdominal pain...
February 16, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28204956/centrally-targeted-pharmacotherapy-for-chronic-abdominal-pain-understanding-and-management
#8
Hans Törnblom, Douglas A Drossman
Chronic abdominal pain has a widespread impact on the individual and the society. Identifying and explaining mechanisms of importance for the pain experience within a biopsychosocial context are central in order to select treatment that has a chance for symptom reduction. With current knowledge of brain-gut interactions, chronic abdominal pain, which mostly appears in functional gastrointestinal disorders, to a large extent involves pain mechanisms residing within the brain. As such, the use of centrally targeted pharmacotherapy as an effective treatment option is obvious in a selected number of patients...
February 16, 2017: Handbook of Experimental Pharmacology
https://www.readbyqxmd.com/read/28195229/international-spinal-cord-injury-bowel-function-basic-data-set-version-2-0
#9
K Krogh, A Emmanuel, B Perrouin-Verbe, M A Korsten, M J Mulcahey, F Biering-Sørensen
STUDY DESIGN: International expert working group. OBJECTIVES: To revise the International Spinal Cord Injury (SCI) Bowel Function Basic Data Set as a standardized format for the collecting and reporting of a minimal amount of information on bowel function in clinical practice and research. SETTING: Working group appointed by the American Spinal injury association (ASIA) and the International Spinal Cord Society (ISCoS). METHODS: The draft prepared by the working group was reviewed by the International SCI Data Set Committee and later by members of the ISCoS Executive and Scientific Committees and the ASIA board...
February 14, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28191706/g-protein-coupled-estrogen-receptor-and-estrogen-receptor-ligands-regulate-colonic-motility-and-visceral-pain
#10
M Zielińska, J Fichna, M Bashashati, S Habibi, A Sibaev, J-P Timmermans, M Storr
BACKGROUND: Diarrhea-predominant irritable bowel syndrome (IBS-D) is a functional gastrointestinal (GI) disorder, which occurs more frequently in women than men. The aim of our study was to determine the role of activation of classical estrogen receptors (ER) and novel membrane receptor, G protein-coupled estrogen receptor (GPER) in human and mouse tissue and to assess the possible cross talk between these receptors in the GI tract. METHODS: Immunohistochemistry was used to determine the expression of GPER in human and mouse intestines...
February 12, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28187396/methyl-orvinol-dual-activity-opioid-receptor-ligand-inhibits-gastrointestinal-transit-and-alleviates-abdominal-pain-in-the-mouse-models-mimicking-diarrhea-predominant-irritable-bowel-syndrome
#11
Marta Zielińska, Agata Jarmuż, Andrzej Wasilewski, Gerta Cami-Kobeci, Stephen Husbands, Jakub Fichna
BACKGROUND: Diarrhea-predominant irritable bowel syndrome (IBS-D) is a functional disorder of the gastrointestinal (GI) tract. The major IBS-D symptoms include diarrhea, abdominal pain and discomfort. High density of opioid receptors (ORs) in the GI tract and their participation in the maintenance of GI homeostasis make ORs ligands an attractive option for developing new anti-IBS-D treatments. The aim of this study was to characterize the effect of methyl-orvinol on the GI motility and secretion and in mouse models mimicking symptoms of IBS-D...
December 5, 2016: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/28176047/gastrointestinal-physiology-and-function
#12
Beverley Greenwood-Van Meerveld, Anthony C Johnson, David Grundy
The gastrointestinal (GI) system is responsible for the digestion and absorption of ingested food and liquids. Due to the complexity of the GI tract and the substantial volume of material that could be covered under the scope of GI physiology, this chapter briefly reviews the overall function of the GI tract, and discusses the major factors affecting GI physiology and function, including the intestinal microbiota, chronic stress, inflammation, and aging with a focus on the neural regulation of the GI tract and an emphasis on basic brain-gut interactions that serve to modulate the GI tract...
February 8, 2017: Handbook of Experimental Pharmacology
https://www.readbyqxmd.com/read/28174447/respiratory-flow-and-vital-signs-associated-with-the-intensity-of-functional-electrical-stimulation-delivered-to-human-abdominal-muscles-during-quiet-breathing
#13
Yoko Sewa, Kazuhide Tomita, Yukako Okuno, Hirotaka Ose, Shigeyuki Imura
[Purpose] The purpose of this study was to examine the effects of increasing the intensity of functional electrical stimulation delivered to abdominal muscles during quiet breathing on respiratory flow, vital signs and pain in healthy subjects. [Subjects and Methods] Electrical stimulation was delivered bilaterally using one pair of high-conductivity gel-skin plate electrodes, placed on both sides of the abdomen, to nine healthy males. Subjects were required to breathe normally through a face mask for 2 minutes while in a supine position...
December 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28162464/-236-impaired-conditioned-pain-modulation-in-youth-with-functional-abdominal-pain
#14
M Morris, L Walker, S Bruehl, A Sherman, A Mielock, U Rao
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28162383/-159-categorizing-risk-for-long-term-disability-in-youth-with-functional-abdominal-pain
#15
S Nelson, A Jagpal, J Peugh, M Farrell, M Cohen, A Mezoff, A Lynch-Jordan, S Kashikar-Zuck, N Cunningham
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28156639/determining-priority-symptoms-of-women-with-recurrent-ovarian-cancers-a-gynecologic-oncology-group-study
#16
Lari B Wenzel, Sandra Ward, Susan M Sereika, Robert P Edwards, Michael Spring, Catherine M Bender, Richard T Penson, Teresa Hagan
: 101 Background: The purpose of this study is to recommend a core set of priority symptoms to be assessed in research and clinical settings for women with recurrent ovarian cancers. METHODS: We used baseline data of 497 women with recurrent ovarian, fallopian, or primary peritoneal cancer participating in a symptom management randomized clinical trial (GOG-0259) to identify a core index of patient-reported priority symptoms. We used the Symptom Representation Questionnaire to assess priority rankings of 28 symptoms based on four criteria: (1) symptom prevalence, (2) patient-reported symptom severity, (3) percentage of women identifying each symptom as one of top three symptoms "I would like to get better control over", and (4) the association between symptom severity and functional wellbeing as measured by the Functional Assessment of Cancer Therapy - Ovarian...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28155576/diagnosis-of-pseudomyxoma-peritonei-via-endoscopic-ultrasound-guided-fine-needle-aspiration-a-case-report-and-review-of-literature
#17
Umar Darr, Anas Renno, Turki Alkully, Zubair Khan, Abhinav Tiwari, Waleed Zeb, Jenna Purdy, Ali Nawras
INTRODUCTION: Pseudomyxoma peritonei (PMP) is a rare condition caused by mucinous adenocarcinoma cancerous cells that produce abundance of mucin or gelatinous ascites. This cancer can cause tissue fibrosis and can impair normal organ function. Diagnosis can involve multiple imaging modalities including CT scan. There have been few cases of endoscopic ultrasound (EUS) being used as a means for diagnosis of this condition. Here we report a second case of PMP with a previous history of appendectomy diagnosed with EUS guided fine needle aspiration (FNA) biopsy...
February 3, 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/28152493/huge-rectovesical-fistula-due-to-long-term-retention-of-a-rectal-foreign-body-a-case-report-and-review-of-the-literature
#18
Yoshiyuki Kiyasu, Nobuyasu Kano
INTRODUCTION: Most patients with foreign bodies in their rectums present to medical institutions within a few days. In this report, we describe a foreign body in the rectum in situ for 5 months that resulted in a huge rectovesical fistula 4cm in diameter, requiring emergency laparotomy. PRESENTATION OF CASE: A 59-year-old man, who had undergone rectal foreign body extraction via the anal canal without any complications 7 years previously, presented with abdominal pain and diarrhea...
January 18, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28146002/development-of-the-ibd-disk-a-visual-self-administered-tool-for-assessing-disability-in-inflammatory-bowel-diseases
#19
Subrata Ghosh, Edouard Louis, Laurent Beaugerie, Peter Bossuyt, Guillaume Bouguen, Arnaud Bourreille, Marc Ferrante, Denis Franchimont, Karen Frost, Xavier Hebuterne, John K Marshall, Ciara OʼShea, Greg Rosenfeld, Chadwick Williams, Laurent Peyrin-Biroulet
BACKGROUND: The Inflammatory bowel disease (IBD) Disability Index is a validated tool that evaluates functional status; however, it is used mainly in the clinical trial setting. We describe the use of an iterative Delphi consensus process to develop the IBD Disk-a shortened, self-administered adaption of the validated IBD Disability Index-to give immediate visual representation of patient-reported IBD-related disability. METHODS: In the preparatory phase, the IBD CONNECT group (30 health care professionals) ranked IBD Disability Index items in the perceived order of importance...
January 31, 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28144414/comparison-of-lateral-abdominal-muscle-thickness-and-cross-sectional-area-of-multifidus-in-adolescent-soccer-players-with-and-without-low-back-pain-a-case-control-study
#20
Pardis Noormohammadpour, Alireza Hosseini Khezri, Paweł Linek, Mohammad Ali Mansournia, Alireza Hassannejad, Ali Younesian, Farzin Farahbakhsh, Ramin Kordi
BACKGROUND: Low back pain (LBP) is a common complaint amongst adolescent athletes. While different studies have shown association between LBP and trunk muscle thickness in the general population, few articles have studied it in adolescent athletes. OBJECTIVES: The aim of this study is to compare lateral abdominal muscle thickness and function, and cross sectional area (CSA) of lumbar multifidus (LM) in adolescent soccer players with and without LBP. METHODS: In total, 28 adolescent soccer players with and without LBP, from the premier league participated in this study...
December 2016: Asian Journal of Sports Medicine
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