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Diverticular diseases

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https://www.readbyqxmd.com/read/29679691/newly-developed-endoscopic-detachable-snare-ligation-therapy-for-colonic-diverticular-hemorrhage-a-multicenter-phase-ii-trial-with-videos
#1
Daisuke Akutsu, Toshiaki Narasaka, Katsumasa Kobayashi, Kenji Matsuda, Mariko Wakayama, Yoshinori Hiroshima, Shinji Endo, Takashi Mamiya, Takahisa Watahiki, Kazuto Ikezawa, Hiroyasu Ishida, Mitsuaki Hirose, Yuji Mizokami, Ichinosuke Hyodo
BACKGROUND AND AIMS: We previously reported preliminary safety results for a new method, endoscopic detachable snare ligation (EDSL), for diverticular hemorrhage. This method does not need endoscope removal to attach a ligation device after detection of the bleeding site. The aim of the present study was to evaluate the efficacy and safety of EDSL in a larger patient population. METHODS: This prospective study was conducted in 12 institutions. Patients suspected of having diverticular hemorrhage without serious systemic disease were enrolled...
April 18, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29672291/initial-management-of-colonic-diverticular-bleeding-observational-study
#2
Michiko Wada, Motohiko Kato, Yuichiro Hirai, Yoko Kubosawa, Yukie Sunata, Keiichiro Abe, Tetsu Hirata, Yoshiaki Takada, Shigeo Banno, Yusaku Takatori, Satoshi Kinoshita, Hideki Mori, Kaoru Takabayashi, Miho Kikuchi, Masahiro Kikuchi, Masayuki Suzuki, Takanori Kanai, Toshio Uraoka
BACKGROUND/AIMS: Although colonic diverticular bleeding (CDB) often ceases spontaneously, re-bleeding occurs in about 30%. Bleeding diverticulum can be treated directly by endoscopic hemostasis; however, it is difficult to perform colonoscopy in all cases with limited medical resource and certain risks. The aim of this study was to clarify who should undergo colonoscopy as well as appropriate methods of initial management in CDB patients. METHODS: A total of 285 patients who were diagnosed as CDB and underwent colonoscopy from March 2004 to October 2015 were retrospectively analyzed...
April 19, 2018: Digestion
https://www.readbyqxmd.com/read/29672283/current-controversies-in-the-management-of-diverticulitis-a-review
#3
Deirdre M Nally, Dara O Kavanagh
BACKGROUND: Symptomatic diverticular disease is challenging for patients, clinicians and health services. The prevalence increases with age and BMI and as such, the burden of this disease is set to increase with higher rates of acute presentations already documented. The natural history of recurrent episodes, complications and symptom progression is not fully understood. Furthermore, medical and surgical management strategies are under constant appraisal, debate and evolution. METHODS: A review of the contemporary literature was performed to examine the emerging trend towards conservative treatment...
April 19, 2018: Digestive Surgery
https://www.readbyqxmd.com/read/29671060/the-role-of-body-composition-in-diverticular-disease
#4
Julia Freckelton, Darcy Holt, Adina Borsaru, StellaMay Gwini, Daniel Croagh, Gregory Moore
BACKGROUND: Diverticular disease is a common, chronic inflammatory disease of the bowel. This study investigates the differences in body composition between patients with diverticular disease and those without. METHODS: Appropriate patients were identified using a search of the radiology database. Demographic and disease information was gathered using scanned medical records. Body composition analysis was performed at level L3 using single-slice computed tomography techniques...
April 18, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29623099/treatment-of-diverticular-disease-an-update-on-latest-evidence-and-clinical-implications
#5
REVIEW
Marilia Carabotti, Bruno Annibale
Background: Diverticular disease (DD) is a common condition, especially in Western countries. In about 80% of patients, colonic diverticula remain asymptomatic (diverticulosis), while approximately 20% of patients may develop abdominal symptoms (symptomatic uncomplicated diverticular disease, SUDD) and, eventually complications as acute diverticulitis (AD). The management of this condition has been improved, and in the last five years European countries and the USA have published guidelines and recommendations...
2018: Drugs in Context
https://www.readbyqxmd.com/read/29614301/association-between-obesity-and-weight-change-and-risk-of-diverticulitis-in-women
#6
Wenjie Ma, Manol Jovani, Po-Hong Liu, Long H Nguyen, Yin Cao, Idy Tam, Kana Wu, Edward L Giovannucci, Lisa L Strate, Andrew T Chan
BACKGROUND & AIMS: There is little evidence that adiposity associates with diverticulitis-especially among women. We conducted a comprehensive evaluation of obesity, weight change, and incidence of diverticulitis in a large cohort of women. METHODS: We conducted a prospective cohort study of 46,079 women enrolled in the Nurses' Health Study, 61-89 years old and free of diverticulitis, diverticular bleeding, cancers, or inflammatory bowel disease at baseline (in 2008)...
March 31, 2018: Gastroenterology
https://www.readbyqxmd.com/read/29607785/the-use-of-probiotics-in-different-phases-of-diverticular-disease
#7
Veronica Ojetti, Carmine Petruzziello, Silvia Cardone, Luisa Saviano, Alessio Migneco, Luca Santarelli, Maurizio Gabrielli, Raffaella Zaccaria, Loris Lopetuso, Marcello Covino, Marcello Candelli, Antonio Gasbarrini, Francesco Franceschi
BACKGROUND & AIMS: Diverticular Disease (DD) is a common clinical condition with a dramatic increasing of the prevalence among industrialized countries. Based on the most used classification, DD may be divided into asymptomatic diverticulosis, symptomatic uncomplicated diverticular disease and complicated diverticular disease. Since recent studies pointed out the role of GUT microbiota imbalance in promoting diverticular formation and inflammation, we have designed a systematic review focusing on the possible role of probiotics in the management of this condition...
April 2, 2018: Reviews on Recent Clinical Trials
https://www.readbyqxmd.com/read/29600834/colovesical-fistula-complicating-diverticular-disease-diagnosis-and-surgical-management-in-elderly
#8
Marco Biffoni, Paolo Urciuoli, Chiara Eberspacher, Alberto Santoro, Daniele Pironi, Salvatore Sorrenti
No abstract text is available yet for this article.
March 30, 2018: Minerva Chirurgica
https://www.readbyqxmd.com/read/29596125/diverticular-disease-traditional-and-evolving-paradigms
#9
(no author information available yet)
No abstract text is available yet for this article.
March 2018: Gastroenterology Nursing: the Official Journal of the Society of Gastroenterology Nurses and Associates
https://www.readbyqxmd.com/read/29596124/diverticular-disease-traditional-and-evolving-paradigms
#10
Lenore Lamanna, Patricia E Moran
Diverticular disease includes diverticulosis, which are sac protrusions of the intestinal mucosa, and diverticulitis, inflammation of the diverticula. Diverticular disease is listed as one of the top 10 leading physician diagnoses for gastrointestinal disorders in outpatient clinic visits in the United States. There are several classifications of diverticular disease ranging from asymptomatic diverticulosis to diverticulitis with complications. Several theories are linked to the development of diverticula which includes the physiology of the colon itself, collagen cross-linking, and recently challenged, low-fiber intake...
March 2018: Gastroenterology Nursing: the Official Journal of the Society of Gastroenterology Nurses and Associates
https://www.readbyqxmd.com/read/29582959/-a-cause-of-acute-renal-dysfunction-a-giant-bladder-diverticulum
#11
Laura Rivoli, Giuseppe Leonardi, Chiara Scafuro, Giuseppe Ucciero, Michele Palumbo, Giuseppe Galluccio, Mariadelina Simeoni, Maria Capria, Giorgio Fuiano
We describe the case of a previously 77-year-old man who accessed in our Nephrology Unit for acute kidney injury (AKI) on chronic kidney disease (CKD), gastric discomfort and vague urinary symptoms with apparently preserved diuresis and suspected "ascites". Physical examination confirmed the presence of abdominal effusion, even though ultrasound abdominal examination revealed the presence of a giant diverticular urinary bladder with bilateral hydronephrosis. We discuss the diagnostic and therapeutic approach of these rare complications by briefly reviewing the technical aspects and the possible consequences...
March 2018: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/29560954/-short-term-outcomes-of-laparoscopic-assisted-procedures-for-chronic-complications-of-diverticular-disease
#12
S I Achkasov, Yu A Shelygin, A I Moskalev, Yu L Trubacheva, S A Senashenko
AIM: To estimate efficacy of laparoscopic-assisted procedures for chronic complications of diverticular disease (DD). MATERIAL AND METHODS: It was made a prospective comparative study within 2007-2015. Inclusion criteria were verified chronic DD (>6 weeks after the first attack) and bowel resection followed by primary anastomosis. EXCLUSION CRITERIA: contraindications for pneumoperitoneum, BMI ≥35 kg/m2 , infiltrate dimension >10 cm, preoperatively non-excluded neoplasm...
2018: Khirurgiia
https://www.readbyqxmd.com/read/29536239/elective-vs-early-elective-surgery-in-diverticular-disease-a-retrospective-study-on-the-optimal-timing-of-non-emergency-treatment
#13
Felix Benjamin Warwas, Berthold Schneider
PURPOSE: This study set out to compare the in-hospital outcomes of early elective and elective laparoscopic sigmoidectomy due to diverticulitis. METHODS: We examined the data for 378 diverticulitis patients who received an elective laparoscopic sigmoid resection between 2008 and 2012. We divided the patients into two groups: elective (group A, n = 278) and early elective (group B, n = 100). Patients in group A received surgery during the inflammation-free interval, and those in group B immediately after treating the attack with IV antibiotics for a mean period of 8 days (IQR = 3)...
March 13, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29536238/damage-control-surgery-in-perforated-diverticulitis-ongoing-peritonitis-at-second-surgery-predicts-a-worse-outcome
#14
M A Sohn, A Agha, P Steiner, A Hochrein, M Komm, R Ruppert, P Ritschl, F Aigner, I Iesalnieks
PURPOSE: Damage control strategy (DCS) is a two-staged procedure for the treatment of perforated diverticular disease complicated by generalized peritonitis. The aim of this retrospective multicenter cohort study was to evaluate the prognostic impact of an ongoing peritonitis at the time of second surgery. METHODS: Consecutive patients who underwent DCS for perforated diverticular disease of the sigmoid colon with generalized peritonitis at four surgical centers were included...
March 13, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29533249/a-variant-of-col3a1-rs3134646-is-associated-with-risk-of-developing-diverticulosis-in-white-men
#15
Matthias Christian Reichert, Juozas Kupcinskas, Marcin Krawczyk, Christoph Jüngst, Markus Casper, Frank Grünhage, Beate Appenrodt, Vincent Zimmer, Susanne Nicole Weber, Algimantas Tamelis, Jaune Ieva Lukosiene, Neringa Pauziene, Gediminas Kiudelis, Laimas Jonaitis, Christoph Schramm, Tobias Goeser, Antje Schulz, Maciej Malinowski, Matthias Glanemann, Limas Kupcinskas, Frank Lammert
BACKGROUND: Colonic diverticulosis is one of the most common gastroenterological disorders. Although diverticulosis is typically benign, many individuals develop diverticulitis or other aspects of diverticular disease. Diverticulosis is thought to stem from a complex interaction of environmental, dietary, and genetic factors; however, the contributing genetic factors remain unknown. OBJECTIVE: The aim of our present study was to determine the role of genetic variants within genes encoding for collagens of the connective tissue in diverticulosis...
May 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29525902/quality-of-life-after-laparoscopic-sigmoid-resection-for-uncomplicated-diverticular-disease
#16
Lino Polese, Alice Bressan, Edoardo Savarino, Massimo Vecchiato, Angelo Turoldo, Annachiara Frigo, Giacomo Carlo Sturniolo, Nicolò De Manzini, Roberto Petri, Stefano Merigliano
PURPOSE: The study aimed to evaluate the QoL in patients who underwent elective surgery for uncomplicated diverticulitis using a recently developed diverticulitis quality of life questionnaire (DV-QoL). METHODS: All consecutive patients who underwent surgery for uncomplicated diverticulitis or who were hospitalized and treated conservatively for acute uncomplicated diverticulitis episodes in three referral centers, in a 5-year period, were included in the study...
March 10, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29520987/effect-of-mesalazine-on-recurrence-of-diverticulitis-in-patients-with-symptomatic-uncomplicated-diverticular-disease-a-meta-analysis-with-trial-sequential-analysis-of-randomised-controlled-trials
#17
REVIEW
Rao Muhammad Asaf Khan, Baqar Ali, Shahin Hajibandeh, Shahab Hajibandeh
OBJECTIVES: To investigate the effect of mesalazine on recurrence of diverticulitis in patients with symptomatic uncomplicated diverticular disease (SUDD). METHODS: We performed a systematic review and conducted a search of electronic information sources to identify all randomised controlled trials (RCTs) investigating the effect of mesalazine on the recurrence of diverticulitis in patients with SUDD. We used the Cochrane tool to assess the quality of included studies...
March 9, 2018: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29517710/persistent-increased-enteric-glial-expression-of-s100%C3%AE-is-associated-with-low-grade-inflammation-in-patients-with-diverticular-disease
#18
François Cossais, Sebastian Leuschner, Martina Barrenschee, Christina Lange, Michael Ebsen, Ilka Vogel, Martina Böttner, Thilo Wedel
BACKGROUND: Diverticular disease (DD) is a common gastrointestinal inflammatory disorder associated with an enteric neuropathy. Although enteric glial cells (EGCs) are essential regulators of intestinal inflammation and motility functions, their contribution to the pathophysiology of DD remains unclear. Therefore, we analyzed the expression of specific EGC markers in patients with DD. MATERIALS AND METHODS: Expression of the glial markers S100β, GFAP, Sox10, and Connexin 43 was analyzed by real-time quantitative PCR in colonic specimens of patients with DD and in that of controls...
March 6, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29505648/diverticular-disease-the-old-the-new-and-the-ever-changing-view
#19
Michael S DiSiena, John W Birk
Our understanding of diverticular disease has evolved significantly during the last 25 years, and as such, a reexamination is in order. We performed a literature search for the years 1960-2017 of PubMed, Medline, and Google Scholar for updates regarding the epidemiology, risk factors, and therapies for traditional diverticulitis as well as the recently described subtypes of diverticular disease, segmental colitis associated with diverticulosis, and symptomatic uncomplicated diverticular disease. Although the prevalence of diverticulosis is still extremely common in the general population, the literature suggests that the incidence of diverticulitis is much less than previously believed and occurrences do not necessarily increase with age...
March 2018: Southern Medical Journal
https://www.readbyqxmd.com/read/29500612/-diverticular-disease-complications-and-differential-diagnosis
#20
REVIEW
A G Schreyer
BACKGROUND: Diverticular disease is becoming increasingly more common in the western world. It is clinically subdivided into uncomplicated diverticular disease and diverticular disease with a complicated course. In approximately 20% of cases the diverticula will become symptomatic during the lifetime of patients. RESULTS: In contrast to previous medical opinions, the occurrence of diverticula cannot be prevented by a diet rich in fiber; however, the development into complicated diverticulitis can be reduced by dietary measures...
April 2018: Der Radiologe
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