Jakub Liu, Magdalena Mroczek, Anna Mach, Maria Stępień, Angelika Aplas, Bartosz Pronobis-Szczylik, Szymon Bukowski, Magda Mielczarek, Ewelina Gajewska, Piotr Topolski, Zbigniew J Król, Joanna Szyda, Paula Dobosz
The number of cases of pancreatic cancers in 2019 in Poland was 3852 (approx. 2% of all cancers). The course of the disease is very fast, and the average survival time from the diagnosis is 6 months. Only <2% of patients live for 5 years from the diagnosis, 8% live for 2 years, and almost half live for only about 3 months. A family predisposition to pancreatic cancer occurs in about 10% of cases. Several oncogenes in which somatic changes lead to the development of tumours, including genes BRCA1/2 and PALB2, TP53, CDKN2A, SMAD4, MLL3, TGFBR2, ARID1A and SF3B1, are involved in pancreatic cancer...
January 27, 2023: Cancers