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https://www.readbyqxmd.com/read/29346552/safety-profile-of-near-zero-fluoroscopy-atrial-fibrillation-ablation-with-non-fluoroscopic-catheter-visualization-experience-from-1000-consecutive-procedures
#1
Philipp Sommer, Livio Bertagnolli, Simon Kircher, Arash Arya, Andreas Bollmann, Sergio Richter, Sascha Rolf, Gerhard Hindricks
Aims: Efforts to reduce radiation exposure during catheter ablation procedures have included the use of various technological measures. Significant results have been achieved to the point where near lead-free procedures in routine clinical practice has become a realistic goal. The integration of MediGuide technology [non-fluoroscopic catheter visualization technology (NFCV)] and three-dimensional electroanatomical mapping is one of the methods developed in response to radiation reduction initiatives...
January 16, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29344708/treatment-of-combined-traumatic-brain-injury-and-hemorrhagic-shock-with-fractionated-blood-products-versus-fresh-whole-blood-in-a-rat-model
#2
Akiva Leibowitz, Evgeni Brotfain, Leonid Koyfman, Moti Klein, Shmuel Hess, Alexander Zlotnik, Matthew Boyko
INTRODUCTION: Treatment of combined traumatic brain injury and hemorrhagic shock, poses a particular challenge due to the possible conflicting consequences. While restoring diminished volume is the treatment goal for hypovolemia, maintaining adequate cerebral perfusion pressure and avoidance of secondary damage remains a treatment goal for the injured brain. Various treatment modalities have been proposed, but the optimal resuscitation fluid and goals have not yet been clearly defined...
January 17, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29343150/eight-year-outcomes-of-a-competency-based-residency-training-program-in-orthopedic-surgery
#3
Markku T Nousiainen, Polina Mironova, Melissa Hynes, Susan Glover Takahashi, Richard Reznick, William Kraemer, Benjamin Alman, Peter Ferguson
BACKGROUND: The Division of Orthopaedic Surgery at the University of Toronto implemented a pilot residency training program that used a competency-based framework in July of 2009. The competency-based curriculum (CBC) deployed an innovative, modularized approach that dramatically intensified both the structured learning elements and the assessment processes. METHODS: This paper discusses the initial curriculum design of the CBC pilot program; the refinement of the curriculum using curriculum mapping that allowed for efficiencies in educational delivery; details of evaluating resident competence; feedback from external reviews by accrediting bodies; and trainee and program outcomes for the first eight years of the program's implementation...
January 18, 2018: Medical Teacher
https://www.readbyqxmd.com/read/29338664/qualitative-analysis-and-conceptual-mapping-of-patient-experiences-in-home-health-care
#4
Lisa M Lines, Wayne L Anderson, Brian D Blackmon, Cristalle R Pronier, Rachael W Allen, Anne E Kenyon
This study explored patient experiences in home health care through a literature review, focus groups, and interviews. Our goal was to develop a conceptual map of home health care patient experience domains. The conceptual map identifies technical and personal spheres of care, relating prior studies to new focus group and interview findings and identifying the most important domains of care. Study participants (n = 35) most frequently reported the most important domain as staff who are caring, supportive, patient, empathetic, respectful, and considerate (endorsed by 29% of participants)...
January 17, 2018: Home Health Care Services Quarterly
https://www.readbyqxmd.com/read/29334187/surveying-the-landscape-of-optogenetic-methods-for-detection-of-protein-protein-interactions
#5
REVIEW
Matthew D Wiens, Robert E Campbell
Mapping the protein-protein interaction (PPi) landscape is of critical importance to furthering our understanding how cells and organisms function. Optogenetic methods, that is, approaches that utilize genetically encoded fluorophores or fluorogenic enzyme reactions, uniquely enable the visualization of biochemical phenomena in live cells with high spatial and temporal accuracy. Applying optogenetic methods to the detection of PPis requires the engineering of protein-based systems in which an optical signal undergoes a substantial change when the two proteins of interest interact...
January 15, 2018: Wiley Interdisciplinary Reviews. Systems Biology and Medicine
https://www.readbyqxmd.com/read/29325541/interprofessional-collaboration-in-nursing-homes-interprof-development-and-piloting-of-measures-to-improve-interprofessional-collaboration-and-communication-a-qualitative-multicentre-study
#6
Christiane A Müller, Nina Fleischmann, Christoph Cavazzini, Susanne Heim, Svenja Seide, Christina Geister, Britta Tetzlaff, Andreas Hoell, Jochen Werle, Siegfried Weyerer, Martin Scherer, Eva Hummers
BACKGROUND: Given both the increase of nursing home residents forecast and challenges of current interprofessional interactions, we developed and tested measures to improve collaboration and communication between nurses and general practitioners (GPs) in this setting. Our multicentre study has been funded by the German Federal Ministry of Education and Research (FK 01GY1124). METHODS: The measures were developed iteratively in a continuous process, which is the focus of this article...
January 11, 2018: BMC Family Practice
https://www.readbyqxmd.com/read/29322245/interactions-between-incentive-valence-and-action-information-in-a-cued-approach-avoidance-task
#7
Vincent Hoofs, Thomas Carsten, C Nico Boehler, Ruth M Krebs
Environmental stimuli can provoke specific response tendencies depending on their incentive valence. While some studies report positive-approach and negative-avoidance biases, others find no such mappings. To further illuminate the relationship between incentive valence and action requirement, we combined a cued monetary incentive paradigm with an approach/avoidance joystick task. Incentive type was manipulated between groups: The reward group won money, while the punishment group avoided losing money for correct and fast responses to targets following incentive cues...
January 10, 2018: Psychological Research
https://www.readbyqxmd.com/read/29320477/a-global-map-of-travel-time-to-cities-to-assess-inequalities-in-accessibility-in-2015
#8
D J Weiss, A Nelson, H S Gibson, W Temperley, S Peedell, A Lieber, M Hancher, E Poyart, S Belchior, N Fullman, B Mappin, U Dalrymple, J Rozier, T C D Lucas, R E Howes, L S Tusting, S Y Kang, E Cameron, D Bisanzio, K E Battle, S Bhatt, P W Gething
The economic and man-made resources that sustain human wellbeing are not distributed evenly across the world, but are instead heavily concentrated in cities. Poor access to opportunities and services offered by urban centres (a function of distance, transport infrastructure, and the spatial distribution of cities) is a major barrier to improved livelihoods and overall development. Advancing accessibility worldwide underpins the equity agenda of 'leaving no one behind' established by the Sustainable Development Goals of the United Nations...
January 10, 2018: Nature
https://www.readbyqxmd.com/read/29316968/improving-the-interoperability-of-biomedical-ontologies-with-compound-alignments
#9
Daniela Oliveira, Catia Pesquita
BACKGROUND: Ontologies are commonly used to annotate and help process life sciences data. Although their original goal is to facilitate integration and interoperability among heterogeneous data sources, when these sources are annotated with distinct ontologies, bridging this gap can be challenging. In the last decade, ontology matching systems have been evolving and are now capable of producing high-quality mappings for life sciences ontologies, usually limited to the equivalence between two ontologies...
January 9, 2018: Journal of Biomedical Semantics
https://www.readbyqxmd.com/read/29315940/bibliometric-analysis-of-literature-in-pharmacy-education-2000-2016
#10
Waleed M Sweileh, Samah W Al-Jabi, Sa'ed H Zyoud, Ansam F Sawalha
OBJECTIVES: Improving pharmacy education requires continuous research to optimize education and consequently pharmacy practice. The goal of this study is to assess national and international contributions to pharmacy education research and present results in comparative bibliometric format. METHODS: Search strategy based on journal name and specific keywords pertaining to pharmacy education were used to retrieve the worldwide literature in pharmacy education using Scopus database during the period from 2000 to 2016...
January 8, 2018: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/29310208/a-viscous-film-sample-chamber-for-laser-ablation-inductively-coupled-plasma-mass-spectrometry
#11
Damiano Monticelli, Davide Civati, Barbara Giussani, Carlo Dossi, Davide Spanu, Sandro Recchia
Laser Ablation - Inductively Coupled Plasma - Mass Spectrometry (LA-ICP-MS) is a powerful method to determine the elemental composition of solid-state samples as it combines the high sensitivity and isotope selectivity of ICP-MS detection and the simplicity of laser ablation sampling. This technique enables rapid multiple sampling of the analysed material, such as needed for mapping or in-depth profiling applications. However, the duration of these measurements is practically restricted by the time taken for the particle to be transported from the sampling point to the ICP torch...
March 1, 2018: Talanta
https://www.readbyqxmd.com/read/29309993/engineered-cardiac-tissue-patch-maintains-structural-and-electrical-properties-after-epicardial-implantation
#12
Christopher P Jackman, Asvin M Ganapathi, Huda Asfour, Ying Qian, Brian W Allen, Yanzhen Li, Nenad Bursac
Functional cardiac tissue engineering holds promise as a candidate therapy for myocardial infarction and heart failure. Generation of "strong-contracting and fast-conducting" cardiac tissue patches capable of electromechanical coupling with host myocardium could allow efficient improvement of heart function without increased arrhythmogenic risks. Towards that goal, we engineered highly functional 1 cm × 1 cm cardiac tissue patches made of neonatal rat ventricular cells which after 2 weeks of culture exhibited force of contraction of 18...
January 3, 2018: Biomaterials
https://www.readbyqxmd.com/read/29307290/multiple-sclerosis-genetics
#13
Ester Canto, Jorge R Oksenberg
A broad scientific consensus has emerged linking multiple sclerosis (MS) risk to multiple independent and interacting DNA variants that are relatively frequent in the population and act in concert with environmental exposures. The multifactorial, polygenic model of heritability provided the rationale and impetus to pursue genome-wide association studies (GWAS), which have been highly successful in uncovering genetic variants influencing susceptibility. Over 200 loci have been firmly associated with MS susceptibility...
January 2018: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/29297317/identification-of-50%C3%A2-k-illumina-chip-snps-associated-with-resistance-to-spot-blotch-in-barley
#14
Irina V Bykova, Nina M Lashina, Vadim M Efimov, Olga S Afanasenko, Elena K Khlestkina
BACKGROUND: Spot blotch, caused by Cochliobolus sativus, is one of the most widespread and harmful diseases in barley. Identification of genetic loci associated with resistance to C. sativus is of importance for future marker-assisted selection. The goal of the current study was to identify loci conferring seedling resistance to two different pathotypes of C. sativus in the Siberian spring barley core collection. RESULTS: A total of 96 spring barley cultivars and lines were phenotyped at the seedling stage with two C...
December 28, 2017: BMC Plant Biology
https://www.readbyqxmd.com/read/29289076/limitations-on-estimation-of-effective-scatterer-diameters
#15
Yang Zhu, Aiguo Han, William D O'Brien, Michael L Oelze, Michael F Insana
The influence of spatial diversity in acoustic scattering properties on estimates of the effective scatterer diameter (ESD) applied to soft biological tissues is investigated. This study is based on two-dimensional simulations of scattering media, beginning with random distributions of simple disk structures where all scattering features are known exactly. It concludes with an analysis of histology maps from healthy and fatty rabbit liver. Further, the liver histology is decomposed using an orthonormal basis to separate acoustic scattering at various spatial scales and observe how it influences ESD estimates...
December 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/29288739/mapping-the-residual-incidence-of-taeniasis-and-cysticercosis-in-colombia-2009-2013-using-geographical-information-systems-implications-in-public-health-and-travel-medicine
#16
Alfonso J Rodríguez-Morales, María Camila Yepes-Echeverri, Wilmer F Acevedo-Mendoza, Hamilton A Marín-Rincón, Carlos Culquichicón, Esteban Parra-Valencia, Jaime A Cardona-Ospina, Ana Flisser
BACKGROUND: In Colombia, taeniasis and cysticercosis have been significantly reduced over the past decades, however still reported with implications for public health and travel medicine. METHODS: An observational, retrospective study, in which the incidence of taeniasis and cysticercosis (ICD-10 codes B68s/B69s) in Colombia, 2009-2013, was estimated based on data extracted from the Individual Health Records System (Registro Individual de Prestación de Servicios, RIPS) was performed...
December 27, 2017: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/29284862/comparison-of-enhancement-of-analgesic-effect-of-intrathecal-neostigmine-by-intrathecal-clonidine-and-transdermal-nitroglycerin-patch-on-bupivacaine-spinal-anesthesia
#17
Mathew V Mammen, Manoj Tripathi, Harish C Chandola, Amit Tyagi, Prateek Singh Bais, Om Prakash Sanjeev
Background: Relief of pain is very important goal intraoperatively and postoperatively. Neostigmine has been used successfully intrathecally with other agents such as clonidine and opioids for pain relief. Aims: This study aims to compare and evaluate the efficacy and safety of combining intrathecal (IT) neostigmine with IT clonidine and transdermal nitroglycerin (tNTG) patch for the relief of pain in patients after surgery. Settings and Design: This was a randomized, prospective, and comparative study...
October 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29284190/vegetation-cover-in-relation-to-socioeconomic-factors-in-a-tropical-city-assessed-from-sub-meter-resolution-imagery
#18
Sebastián Martinuzzi, Olga M Ramos-González, Tischa A Muñoz-Erickson, Dexter H Locke, Ariel E Lugo, Volker C Radeloff
Fine-scale information about urban vegetation and social-ecological relationships is crucial to inform both urban planning and ecological research, and high spatial resolution imagery is a valuable tool for assessing urban areas. However, urban ecology and remote sensing have largely focused on cities in temperate zones. Our goal was to characterize urban vegetation cover with sub-meter resolution aerial imagery, and identify social-ecological relationships of urban vegetation patterns in a tropical city, the San Juan Metropolitan Area, Puerto Rico...
December 28, 2017: Ecological Applications: a Publication of the Ecological Society of America
https://www.readbyqxmd.com/read/29276490/dual-frequency-head-maps-a-new-method-for-indexing-mental-workload-continuously-during-execution-of-cognitive-tasks
#19
Thea Radüntz
One goal of advanced information and communication technology is to simplify work. However, there is growing consensus regarding the negative consequences of inappropriate workload on employee's health and the safety of persons. In order to develop a method for continuous mental workload monitoring, we implemented a task battery consisting of cognitive tasks with diverse levels of complexity and difficulty. We conducted experiments and registered the electroencephalogram (EEG), performance data, and the NASA-TLX questionnaire from 54 people...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29260884/engagement-of-stakeholders-in-the-development-of-a-theory-of-change-for-handwashing-and-sanitation-behaviour-change
#20
Emmy De Buck, Karin Hannes, Margaret Cargo, Hans Van Remoortel, Axel Vande Veegaete, Hans-Joachim Mosler, Thashlin Govender, Philippe Vandekerckhove, Taryn Young
A Theory of Change (ToC) is an approach to map programmes aimed at inducing change in a specific context, with the goal of increasing their impact. We applied this approach to the specific case of handwashing and sanitation practices in low- and middle-income countries and developed a ToC as part of a systematic review exercise. Different existing sources of information were used to inform the initial draft of the ToC. In addition, stakeholder involvement occurred and peer review took place. Our stakeholders included methodological (ToC/quantitative and qualitative research) and content experts (WASH (Water, Sanitation, Hygiene)/behaviour change), as well as end-users/practitioners, policy-makers and donors...
December 20, 2017: International Journal of Environmental Health Research
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