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https://www.readbyqxmd.com/read/28944966/inpatient-management-of-children-with-recessive-dystrophic-epidermolysis-bullosa-a-review
#1
REVIEW
Alvin W Li, Brea Prindaville, Scot T Bateman, Timothy E Gibson, Karen Wiss
Recessive dystrophic epidermolysis bullosa is a disorder marked by skin and mucosal blistering after minimal trauma. Even the most routine procedures in the hospital, if done incorrectly, can precipitate extensive skin loss, pain, and scarring. Most providers have little experience working with patients with this degree of skin fragility. When a person with recessive dystrophic epidermolysis bullosa is admitted to the hospital, there are multiple considerations to keep in mind while strategizing an effective care plan: avoidance of new blisters with a "hands-off" approach; careful consideration of all indwelling devices; symptomatic management of pain, itch, and anxiety; coordination of dressing changes; aggressive treatment of skin infections; environmental and staffing considerations; and awareness of other chronic complications that affect care, such as anemia, malnutrition, and chronic pain...
September 25, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28944604/the-social-practice-of-medical-guanxi-personal-connections-and-patient-physician-trust-in-china-an-anthropological-and-ethical-tsudy
#2
Xiang Zou, Yu Cheng, Jing-Bao Nie
In China's healthcare sector, a popular and socio-culturally distinctive phenomenon known as guanxi jiuyi (medical guanxi), whereby patients draw on their guanxi (personal connections) with physicians when seeking healthcare, is thriving. Integrating anthropological investigation with normative inquiry, this paper examines medical guanxi through the lens of patient-physician trust and mistrust. The first-hand empirical data acquired - on the lived experiences and perspectives of both patients and physicians - is based on six months' fieldwork carried out in a county hospital in Guangdong, southern China, which included in-depth interviews with 20 patients and 20 medical professionals...
September 25, 2017: Developing World Bioethics
https://www.readbyqxmd.com/read/28944583/venous-anastomosis-using-a-nonpenetrating-vascular-closure-system-in-orthotopic-liver-transplantation
#3
Yuan Wang, Zhao Xin, Bing Pan, Shao-Cheng Lv, Xing-Mao Zhang, Zhi-Hua Zhang, Li-Xin Li, Xian-Liang Li, Qiang He
BACKGROUND: A nonpenetrating vessel closure system (VCS-AnastoClip(®) ) may facilitate vascular anastomosis. The purpose of this study is to explore the utilization of a nonpenetrating VCS in orthotopic liver transplantation (OLT). METHODS: From January 2015 to February 2017, patients who underwent OLT were divided into two groups, i.e., those who underwent nonpenetrating VCS application for inferior vena cava (IVC) and portal vein (PV) reconstructions and those who underwent hand sewing for these purposes...
September 25, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/28944576/medications-affecting-healing-an-evidence-based-analysis
#4
Hanan Khalil, Marianne Cullen, Helen Chambers, Matthew McGrail
The purpose of this arm of the study was to investigate the impact of medication on healing times of the various wound types, including acute wounds and leg ulcers. A prospective longitudinal study design was used, with de-identified data collected using an electronic mobile wound care database system. Three main categories of data were collected, including patients' demographics, wounds types and treatment characteristics. For acute wounds, there was a total of 1732 patients with 2089 acute wounds. The average healing time was about 35 days...
September 25, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28944390/a-topological-study-of-chemical-bonds-under-pressure-solid-hydrogen-as-a-model-case
#5
Vanessa Riffet, Vanessa Labet, Julia Contreras-García
It is now well recognized that a fundamental understanding of the rules that govern chemistry under pressure is still lacking. Hydrogen being the "simplest" element as well as a central core to high pressure physics, we undertake a general study of the changes in the chemical bonding under pressure. We start from a simple trimer unit that has been found in high pressure phases, whose behavior has been found to reveal the basics of hydrogen polymerization under pressure. Making use of bond analysis tools, mainly the NCI (noncovalent interactions) index, we show that polymerization takes place in three steps: dipolar attraction, repulsion and bond formation...
September 25, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28944382/s-nitrosothiols-chemistry-and-reactions
#6
Caihong Zhang, Tyler D Biggs, Nelmi O Devarie-Baez, Shaomin Shuang, Chuan Dong, Ming Xian
The formation of S-nitrosothiols (SNO) in protein cysteine residues is an important post-translational modification elicited by nitric oxide (NO). This process is involved in virtually every class of cell signaling and has attracted considerable attention in redox biology. On the other hand, their unique structural characters make SNO potentially useful synthons. In this review, we summarized the fundamental chemical/physical properties of SNO. We also highlighted the reported chemical reactions of SNO, including the reactions with phosphine reagents, sulfinic acids, various nucleophiles, SNO-mediated radical additions, and the reactions of acyl SNO species...
September 25, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28944373/misfit-of-implant-prostheses-and-its-impact-on-clinical-outcomes-definition-assessment-and-a-systematic-review-of-the-literature
#7
Joannis Katsoulis, Takuro Takeichi, Ana Sol Gaviria, Lukas Peter, Konstantinos Katsoulis
BACKGROUND AND AIM: Compromised fit between the contact surfaces of screw-retained implant-supported fixed dentures (IFDs) is thought to create uncontrolled strains in the prosthetic components and peri-implant tissues, thus evoking biological and technical complications such as bone loss, screw loosening, component fractures and, at worst, loss of implants or prostheses. The aim of this systematic review was to evaluate the impact of marginal misfit on the clinical outcomes of IFDs, and to elucidate definition and assessment methods for passive fit...
2017: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/28944368/impact-of-prosthetic-material-on-mid-and-long-term-outcome-of-dental-implants-supporting-single-crowns-and-fixed-partial-dentures-a-systematic-review-and-meta-analysis
#8
Samir Abou-Ayash, Malin Strasding, Gerta Rücker, Wael Att
AIM: The impact of prosthetic material selection on implant survival is not clear. The current criteria for choosing a prosthetic material seem to be based on clinician preferences. This systematic review aims to evaluate the impact of restorative materials on the mid- and long-term survival of implants supporting single crowns and fixed partial dentures. MATERIALS AND METHODS: Hand and MEDLINE searches were performed to identify relevant literature for single crowns (SC) and fixed partial dentures (FPD)...
2017: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/28944358/ceramic-vs-composite-veneering-of-full-arch-implant-supported-zirconium-frameworks-assessing-patient-preference-and-satisfaction-a-crossover-double-blind-randomised-controlled-trial
#9
Mauro Merli, Eugenio Bianchini, Giorgia Mariotti, Marco Moscatelli, Matteo Piemontese, Giorgio Rappelli, Michele Nieri
PURPOSE: The objectives of this two-period, crossover, mono-centred, double-blind, randomised controlled trial (RCT) were to compare two different materials used for full arch implant-supported prosthetic restorations with regard to patient preference and impact on a patient's quality of life. MATERIALS AND METHODS: Edentulous patients requesting one full arch restoration in the mandible or maxilla supported by dental implants were included in this study. Patients were randomised to receive either a full arch zirconia framework hand-veneered with ceramic, or a full arch zirconia framework hand-veneered with composite material...
2017: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/28944313/effect-of-tobacco-control-policies-on-perinatal-and-child-health-a-systematic-review-and-meta-analysis
#10
Timor Faber, Arun Kumar, Johan P Mackenbach, Christopher Millett, Sanjay Basu, Aziz Sheikh, Jasper V Been
BACKGROUND: Tobacco smoking and smoke exposure during pregnancy and childhood cause considerable childhood morbidity and mortality. We did a systematic review and meta-analysis to investigate whether implementation of WHO's recommended tobacco control policies (MPOWER) was of benefit to perinatal and child health. METHODS: We searched 19 electronic databases, hand-searched references and citations, and consulted experts to identify studies assessing the association between implementation of MPOWER policies and child health...
September 2017: Lancet. Public Health
https://www.readbyqxmd.com/read/28944260/post-treatment-survivorship-care-needs-of-spanish-speaking-latinas-with-breast-cancer
#11
Anna María Nápoles, Carmen Ortiz, Jasmine Santoyo-Olsson, Anita L Stewart, Howard E Lee, Ysabel Duron, Niharika Dixit, Judith Luce, Diana J Flores
BACKGROUND: A comprehensive assessment of Spanish-speaking breast cancer survivors' (SSBCS) survivorship needs is lacking. OBJECTIVE: Assess SSBCS' post-treatment symptom management, psychosocial, and informational needs. METHODS: 118 telephone surveys and 25 in-person semi-structured interviews with SSBCS, and semi-structured interviews with 5 support providers and 4 physicians who serve SSBCS from 5 Northern California counties. RESULTS: Surveys identified the most bothersome (bothered by it in the past month "somewhat/quite a bit/a lot") physical symptoms as: joint pain, fatigue, hot flashes, numbness in hands/feet, and vaginal dryness...
2017: Journal of Community and Supportive Oncology
https://www.readbyqxmd.com/read/28944217/activation-of-inkt-cells-prevents-salmonella-enterocolitis-and-salmonella-induced-reactive-arthritis-by-downregulating-il-17-producing-%C3%AE-%C3%AE-t-cells
#12
Mariángeles Noto Llana, Sebastián H Sarnacki, Andrea L Morales, María Del R Aya Castañeda, Mónica N Giacomodonato, Guillermo Blanco, María C Cerquetti
Reactive arthritis (ReA) is an inflammatory condition of the joints that arises following an infection. Salmonella enterocolitis is one of the most common infections leading to ReA. Although the pathogenesis remains unclear, it is known that IL-17 plays a pivotal role in the development of ReA. IL-17-producers cells are mainly Th17, iNKT, and γδT lymphocytes. It is known that iNKT cells regulate the development of Th17 lineage. Whether iNKT cells also regulate γδT lymphocytes differentiation is unknown...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28944083/white-matter-changes-in-corticospinal-tract-associated-with-improvement-in-arm-and-hand-functions-in-incomplete-cervical-spinal-cord-injury-pilot-case-series
#13
Nuray Yozbatiran, Zafer Keser, Khader Hasan, Argyrios Stampas, Radha Korupolu, Sam Kim, Marcia K O'Malley, Felipe Fregni, Gerard E Francisco
INTRODUCTION: This is a prospective clinical pilot case series. Improvement of arm and hand functions after spinal cord injury (SCI) is one of the major rehabilitation goals. Electrical stimulation of the primary motor cortex via transcranial direct current stimulation (tDCS) coupled with high-intensity repetitive motor training may have potential to facilitate improvement in motor function in chronic, incomplete cervical SCI. We investigated the relationship between motor recovery and changes in white matter integrity in response to treatment intervention...
2017: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/28944060/one-ion-to-rule-them-all-combined-antibacterial-osteoinductive-and-anticancer-properties-of-selenite-incorporated-hydroxyapatite
#14
Vuk Uskoković, Maheshwar Adiraj Iyer, Victoria M Wu
Although hydroxyapatite (HAp) has been doped with dozens of different ions, the quest for an ion imparting a combination of properties conducive to bone healing is still ongoing. Because of its protean potency and the similarity in size and shape to the phosphate tetrahedron, selenite ion presents a natural ionic substitute in HAp. The incorporation of selenite into synthetic HAp using two different methods - co-precipitation and ion-exchange sorption - was studied for its effect on crystal properties and on a triad of biological responses: antibacterial, anticancer and osteoinductive...
2017: Journal of Materials Chemistry. B, Materials for Biology and Medicine
https://www.readbyqxmd.com/read/28944053/implementation-of-who-multimodal-strategy-for-improvement-of-hand-hygiene-a-quasi-experimental-study-in-a-traditional-chinese-medicine-hospital-in-xi-an-china
#15
Li Shen, Xiaoqing Wang, Junming An, Jialu An, Ning Zhou, Lu Sun, Hong Chen, Lin Feng, Jing Han, Xiaorong Liu
BACKGROUND: Hand hygiene (HH) is an essential component for preventing and controlling of healthcare-associated infection (HAI), whereas compliance with HH among health care workers (HCWs) is frequently poor. This study aimed to assess compliance and correctness with HH before and after the implementation of a multimodal HH improvement strategy launched by the World Health Organization (WHO). METHODS: A quasi-experimental study design including questionnaire survey generalizing possible factors affecting HH behaviors of HCWs and direct observation method was used to evaluate the effectiveness of WHO multimodal HH strategy in a hospital of Traditional Chinese Medicine...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/28943983/the-impact-of-drug-related-problems-on-health-related-quality-of-life-among-hypertensive-patients-in-jordan
#16
Rana Abu Farha, Akram Saleh, Salah Aburuz
BACKGROUND: Hypertension is a major cause of cardiovascular diseases with a high prevalence in Jordan. No previous studies have been carried out to determine the effect of the presence of drug-related problems (DRPs) on the health-related quality of life (HRQOL) among hypertensive patients. OBJECTIVES: The purpose of this study was to identify the influence of different types of DRPs on the HRQOL of hypertensive patients. METHODS: A total of 200 hypertensive patients were recruited in this cross-sectional correlation study that was conducted across the cardiac outpatient clinic at Jordan University Hospital...
July 2017: Pharmacy Practice
https://www.readbyqxmd.com/read/28943645/crime-teenage-abortion-and-unwantedness
#17
Gary L Shoesmith
This article disaggregates Donohue and Levitt's (DL's) national panel-data models to the state level and shows that high concentrations of teenage abortions in a handful of states drive all of DL's results in their 2001, 2004, and 2008 articles on crime and abortion. These findings agree with previous research showing teenage motherhood is a major maternal crime factor, whereas unwanted pregnancy is an insignificant factor. Teenage abortions accounted for more than 30% of U.S. abortions in the 1970s, but only 16% to 18% since 2001, which suggests DL's panel-data models of crime/arrests and abortion were outdated when published...
October 2017: Crime and Delinquency
https://www.readbyqxmd.com/read/28943537/transient-prosopometamorphopsia-restricted-to-the-left-eye-caused-by-ischemia-at-the-right-splenium-of-the-corpus-callosum
#18
Naoko Funatsu, Mikito Hayakawa, Naoki Tokuda, Kazunori Toyoda
We herein report a patient who developed transient prosopometamorphopsia restricted to the left eye caused by ischemia of the right splenium of the corpus callosum. A 66-year-old right-handed woman suddenly noticed that the left eyes of people she encountered appeared markedly adducted to their noses. On emergent admission, neurological and ophthalmological examinations revealed no abnormalities. Diffusion-weighted magnetic resonance imaging showed a small, hyperintense lesion at the right splenium of the corpus callosum...
September 25, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28943513/neonatal-diabetes-two-cases-with-isolated-pancreas-agenensis-due-to-homozygous-ptf1a-enhancer-mutations-and-one-with-dend-syndrome-due-to-kcnj11-mutation
#19
Olcay Evliyaoğlu, Oya Ercan, Emel Ataloğlu, Ümit Zübarioğlu, Bahar Özcabı, Aydilek Dağdeviren, Hande Erdoğan, Elisa De Franco, Sian Ellard
Neonatal diabetes mellitus is a rare form of monogenic diabetes which is diagnosed in the first 6 months of life. Here we report three patients with neonatal diabetes; two with isolated pancreas agenesis due to mutations in the PTF1A enhancer and one with DEND syndrome (developmental delay, epilepsy, and neonatal diabetes) due to a KCNJ11 mutation. The two cases with mutations in the distal enhacer of PTF1A had a homozygous g.23508363A>G and a homozygous g.23508437A>G mutation respectively. Previous functional analysis showed that these mutations can decrease expression of PTF1A which is involved in pancreas development...
September 25, 2017: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/28943465/eeg-differences-between-eyes-closed-and-eyes-open-resting-remain-in-healthy-ageing
#20
Robert J Barry, Frances M De Blasio
In young adults and children, the eyes-closed (EC) resting state is one of low EEG arousal, with the change to eyes-open (EO) primarily involving an increase in arousal. We used this arousal perspective to interpret EC/EO differences in healthy young and older adults. EEG was recorded from 20 young (Mage=20.4years) and 20 gender-matched older (Mage=68.2years) right-handed adults during two 3min resting conditions; EC then EO. Older participants displayed less delta and theta, some reduction in alpha, and increased beta...
September 21, 2017: Biological Psychology
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