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https://www.readbyqxmd.com/read/28549364/-an-option-to-restore-ulnar-intrinsic-muscles-when-the-anterior-interosseus-nerve-is-not-available
#1
G A González-Trevizo
BACKGROUND: The peripheral nerve injuries are devastating for the patient; the classic reconstructive options are the Nerve Graft and Tendon Transfers. Lately the Nerve Transfers are being used more and more broadly. They are an excellent option on early injuries and when the motor plate is still alive. The advantages are numerous, because the functional recovery is much better. METHODS AND RESULTS: We report the case of a patient who sustained and injury on the median and ulnar nerve, so the EDQ and ECU branches were used to restore the Ulnar Intrinsic Function...
November 2016: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/28549309/switching-between-intravenous-and-subcutaneous-trastuzumab-safety-results-from-the-prefher-trial
#2
Joseph Gligorov, Giuseppe Curigliano, Volkmar Müller, Ann Knoop, Valerie Jenkins, Sunil Verma, Stuart Osborne, Sabine Lauer, Zuzana Machackova, Lesley Fallowfield, Xavier Pivot
AIM: To assess the safety and tolerability of switching between subcutaneous (SC) and intravenous (IV) trastuzumab in the PrefHer study (NCT01401166). PATIENTS AND METHODS: Patients with HER2-positive early breast cancer completed (neo)adjuvant chemotherapy and were randomised to receive four cycles of SC trastuzumab, via single-use injection device (SID; Cohort 1) or hand-held syringe (Cohort 2), followed by four cycles of IV, or vice versa (the crossover period presented here) as part of their 18 standard cycles of adjuvant trastuzumab treatment...
May 23, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28549210/selecting-sugarcane-genotypes-by-the-selection-index-reveals-high-gain-for-technological-quality-traits
#3
L A Silva, P E Teodoro, L A Peixoto, C Assis, K Gasparini, M H P Barbosa, L L Bhering
Sugarcane (Saccharum sp) is one of the most promising crops and researchers have sought for renewable alternative energy sources to reduce CO2 emission. The study of strategies, which allow breeders in the selection of superior genotypes for many traits simultaneously, is important. Therefore, the objectives of this study were: i) to apply path analysis to better understand the relationship between the lignocellulosic traits and technological quality traits with total recoverable sugars (TRS) and ii) to use several multivariate selection indexes to predict the genetic gain and to select superior genotypes in the sugarcane breeding...
May 25, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28549131/a-novel-cortical-target-to-enhance-hand-motor-output-in-humans-with-spinal-cord-injury
#4
Jinyi Long, Paolo Federico, Monica A Perez
A main goal of rehabilitation strategies in humans with spinal cord injury is to strengthen transmission in spared neural networks. Although neuromodulatory strategies have targeted different sites within the central nervous system to restore motor function following spinal cord injury, the role of cortical targets remain poorly understood. Here, we use 180 pairs of transcranial magnetic stimulation for ∼30 min over the hand representation of the motor cortex at an interstimulus interval mimicking the rhythmicity of descending late indirect (I) waves in corticospinal neurons (4...
June 1, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28549053/does-incremental-positioning-weight-shifts-reduce-pressure-injuries-in-critical-care-patients
#5
Lee Ann Krapfl, Julia Langin, Caitlin A Pike, Patricia Pezzella
BACKGROUND: Incremental positioning or weight shifts are often suggested as an alternative to standard repositioning/turning in critical care patients deemed clinically unstable. OBJECTIVE: This evidence-based report card reviews whether incremental positioning and/or weight shifts reduce hospital-acquired sacral/buttocks pressure injuries in critical care patients deemed too unstable to turn. METHODS AND SEARCH STRATEGY: A scoping review of the literature was conducted for studies related to repositioning and hospital-acquired pressure injuries in high-risk, critical care patients...
May 25, 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28549049/institution-of-a-preoperative-stoma-education-group-class-decreases-rate-of-peristomal-complications-in-new-stoma-patients
#6
Audrey L Stokes, Shelly Tice, Suzi Follett, Diane Paskey, Lini Abraham, Cheryl Bealer, Holly Keister, Walter Koltun, Frances J Puleo
PURPOSE: The purpose of this study was to compare selected postoperative complications (including stomal and peristomal complications), hospital length of stay, and readmission rates in a group of patients who attended a preoperative educational intervention to a retrospective group of patients who did not receive the intervention. DESIGN: Retrospective, comparison cohort study. SUBJECTS AND SETTING: The intervention group comprised 124 patients who attended an educational session for persons with fecal ostomies at a single tertiary care center in the Northeastern United States...
May 25, 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28548997/anterior-inferior-plating-results-in-fewer-secondary-interventions-compared-to-superior-plating-for-acute-displaced-mid-shaft-clavicle-fracture
#7
Rafael Serrano, Amrut Borade, Hassan Mir, Anjan Shah, David Watson, Anthony Infante, Mark A Frankle, Mark A Mighell, H Claude Sagi, Daniel S Horwitz, Roy W Sanders
OBJECTIVES: To determine if a difference in plate position for fixation of acute, displaced, mid-shaft clavicle fractures would affect the rate of secondary intervention. DESIGN: Retrospective Comparative Study SETTING:: two academic Level 1 Regional Trauma Centers PATIENTS:: 510 patients treated surgically for an acutely displaced mid-shaft clavicle fracture between 2000-2013 were identified and reviewed retrospectively at a minimum of 24 months' follow-up (F/U)...
April 5, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28548676/the-diagnosis-and-management-of-chronic-migraine-in-primary-care
#8
Werner J Becker
BACKGROUND: Chronic migraine is common, affecting approximately 1% of the general population, and causes significant disability. OBJECTIVE: To summarize optimal involvement of primary care physicians in chronic migraine care, and to provide algorithms to assist them in the diagnosis and management of patients with chronic migraine. METHODS: An analysis of diagnostic and treatment needs in chronic migraine, based on a synthesis of the medical literature and clinical experience...
May 26, 2017: Headache
https://www.readbyqxmd.com/read/28548647/acute-endophthalmitis-after-cataract-surgery-164-consecutive-cases-treated-at-a-referral-center-in-south-korea
#9
S H Jeong, H J Cho, H S Kim, J I Han, D W Lee, C G Kim, J W Kim
PurposeTo identify prognostic factors in patients referred with endophthalmitis after cataract surgery, and to evaluate the efficacy of primary vitrectomy as an initial management.MethodsOver an eight-year study period, we retrospectively reviewed the medical records of 164 patients who were referred with endophthalmitis following cataract surgery. Treatment generally conformed to standard guidelines, although primary vitrectomy was performed in several eyes with a visual acuity of hand motion or better, depending on the patient's status...
May 26, 2017: Eye
https://www.readbyqxmd.com/read/28548587/comparison-of-efficacy-between-tace-combined-with-apatinib-and-tace-alone-in-the-treatment-of-intermediate-and-advanced-hepatocellular-carcinoma-a-single-center-randomized-controlled-trial
#10
Wei Lu, Xin-Li Jin, Chao Yang, Peng Du, Fu-Qiang Jiang, Jun-Peng Ma, Jian Yang, Peng Xie, Zhe Zhang
OBJECTIVE: This study was designed to compare the clinical efficacy and safety of transcatheter arterial chemoembolization (TACE) combined with apatinib and TACE alone in the treatment of intermediate and advanced hepatocellular carcinoma (HCC). METHODS: From March 2015 to August 2015, a total of 44 patients with moderate and advanced HCC, who were admitted in the Navy General Hospital of China, were included into this study. These patients were randomly divided into two groups: group A and group B...
May 26, 2017: Cancer Biology & Therapy
https://www.readbyqxmd.com/read/28548492/systematic-investigation-of-the-in-situ-reduction-process-from-u-vi-to-u-iv-in-a-phosphonate-system-under-mild-solvothermal-conditions
#11
Lanhua Chen, Juan Diwu, Daxiang Gui, Yaxing Wang, Zhehui Weng, Zhifang Chai, Thomas E Albrecht-Schmitt, Shuao Wang
The oxidation state greatly affects the chemical behavior of uranium in the nuclear fuel cycle and in the environment. Phosphonate ligands, on the other hand, show strong complexation toward uranium at different oxidation states and are widely used in nuclear fuel reprocessing. Therefore, in this work, the reduction behavior of U(VI) with the presence of a phosphonate ligand is investigated under mild solvothermal conditions. By adjusting the reaction time, temperature, and counterion species, a series of uranium diphosphonates including two U(VI), seven U(IV), two mixed-valent U(IV/VI), and one distinct U(IV/V/VI) compounds were obtained...
May 26, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28548458/effector-based-attention-systems
#12
REVIEW
Carolyn J Perry, Mazyar Fallah
Visual processing is known to be enhanced at the end point of eye movements. Feedback within the oculomotor system has been shown to drive these alterations in visual processing. However, we do not simply view the world; we also reach out and interact using our hands. Consequently, it is not surprising that visual processing has also been shown to be altered in near-hand space. A growing body of work documents a myriad of alterations in near-hand visual processing, with little consensus on the neural underpinnings of the effect of the hand...
May 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/28548290/metacarpal-growth-during-adolescence-in-a-longitudinal-south-african-cohort
#13
A Magan, L H Nyati, L K Micklesfield, S A Norris, J M Pettifor
To monitor the drift of the periosteal and endocortical surfaces during metacarpal growth longitudinally, radiogrammetry was carried out on hand-wrist x-rays of 572 children from the Birth to Twenty Bone Health Cohort annually from ages 9-21 years. This is the largest collection of longitudinal x-rays in African children. The 2(nd) metacarpal bone length, bone width and medullary width were measured using digital vernier callipers on a total of 4730 x-rays. Superimposition by Translation and Rotation (SITAR) was used to obtain age at peak metacarpal length velocity (PLV)...
May 26, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28548189/-physical-activity-obesity-and-self-esteem-in-chilean-schoolchildren
#14
Félix Zurita-Ortega, Manuel Castro-Sánchez, Sonia Rodríguez-Fernández, Cristian Cofré-Boladós, Ramón Chacón-Cuberos, Asunción Martínez-Martínez, José Joaquín Muros-Molina
BACKGROUND: Obesity is a worldwide epidemic disease and a problem for the Chilean society. AIM: To analyze the relationship between physical condition, body mass index (BMI), level of physical activity and self-esteem. Material ad Methods: Questionnaires to assess self-esteem (Rosemberg scale) and levels of physical activity (Physical Activity Questionnaire for older Children, PAQ-C) were answered by 515 children aged 10.5 ± 0.5 years from 27 schools of Santiago de Chile...
March 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28548032/impact-of-age-sex-socioeconomic-status-and-physical-activity-on-associated-movements-and-motor-speed-in-preschool-children
#15
Tanja H Kakebeeke, Annina E Zysset, Nadine Messerli-Bürgy, Aziz Chaouch, Kerstin Stülb, Claudia S Leeger-Aschmann, Einat A Schmutz, Amar Arhab, Valentin Rousson, Susi Kriemler, Simone Munsch, Jardena J Puder, Oskar G Jenni
INTRODUCTION: Young children generally show contralateral associated movements (CAMs) when they are making an effort to perform a unimanual task. CAM and motor speed are two relevant aspects of motor proficiency in young children. These CAMs decrease over age, while motor speed increases. As both CAM and motor speed are associated with age, we were interested in whether these two parameters are also linked with each other. METHOD: In this study, three manual dexterity tasks with the dominant and nondominant hands (pegboard, repetitive hand, and repetitive finger tasks) were used to investigate the effect of covariates (age, sex, socioeconomic status, total physical activity) on both motor speed and CAMs in preschool children...
May 26, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/28547952/mir-150-up-regulates-glut1-and-increases-glycolysis-in-osteosarcoma-cells
#16
Guangke Yuan, Yanqing Zhao, Dongjin Wu, Chunzheng Gao
Objective: Osteosarcoma (OS) is the most common malignant bone tumor in children and young adults. Many studies have shown that microRNAs play a critical role in proliferation and metastasis with this tumour type. However, whether aberrant expression might contribute to a metabolism switch in osteosarcoma cases is not clearly understood. In this study, we explored expression and function of miR-150 in osteosarcoma cells. Materials and methods: Expression of miR-150 was assessed by real-time PCR in cell lines and human patient tissues...
April 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28547770/sonographic-appearance-of-subungual-squamous-cell-carcinoma-in-the-hand
#17
Monica Quintana-Codina, Lídia Creus-Vila, Ana Iglesias-Plaza, Maribel Iglesias-Sancho, Gemma Melé-Ninot, Anna Isabel Lázaro-Simó, Montse Salleras-Redonnet
Subungual squamous cell carcinoma is very rare, but it is the most frequent primary malignant tumor of the nail bed. Therefore, its diagnosis and treatment are crucial to ensure a favorable prognosis. We present the sonographic findings in a case of a subungual squamous cell carcinoma. © 2017 Wiley Periodicals, Inc. J Clin Ultrasound, 2017.
May 26, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28547746/the-support-needs-of-parents-having-a-child-with-a-chronic-kidney-disease-a-focus-group-study
#18
W W Geense, B G I van Gaal, J L Knoll, E A M Cornelissen, T van Achterberg
BACKGROUND: Parents of children with a chronic kidney disease (CKD) have a crucial role in the management of their child's disease. The burden on parents is high: they are often exhausted, depressed and experience high levels of stress and a low quality of life, which could have a negative impact on their child's health outcomes. Support aiming at preventing and reducing parental stress is essential. Therefore, it is necessary to have insight in the problems and support needs among these parents...
May 25, 2017: Child: Care, Health and Development
https://www.readbyqxmd.com/read/28547743/unremodelled-and-bradycardic-heart-of-the-anaesthetized-rabbit-is-applicable-for-detection-of-drug-induced-torsades-de-pointes-arrhythmias
#19
Mihoko Hagiwara, Seiji Shibuta, Kazuhiro Takada, Ryuichi Kambayashi, Misako Nakajo, Megumi Aimoto, Yoshinobu Nagasawa, Akira Takahara
BACKGROUND AND PURPOSE: Several rabbit proarrhythmia models have been recently developed by genetic or pharmacological methods to suppress the slow component of delayed rectifier K(+) currents in the ventricle, leading to reduction of the repolarization reserve. The present study was designed to characterize a novel rabbit in vivo proarrhythmia model with severe bradycardia caused by acute atrioventricular block (AVB). EXPERIMENTAL APPROACH: Bradycardia was induced in isoflurane-anaesthetized rabbits by creation of AVB using catheter ablation, and the ventricle was electrically driven at 60 beats min(-1) throughout the experiment except when extrasystole appeared...
May 26, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28547674/diagnostic-accuracy-of-various-modalities-relative-to-open-bone-biopsy-for-detection-of-long-bone-posttraumatic-osteomyelitis
#20
Vivek Chadayammuri, Benoit Herbert, Jiandong Hao, Andreas Mavrogenis, Juan C Quispe, Ji Wan Kim, Heather Young, Mark Hake, Cyril Mauffrey
BACKGROUND: Long bone posttraumatic osteomyelitis (PTOM) is a relatively common complication following surgical fixation of open fractures. There is a lacking consensus on ideal strategies for diagnostic evaluation of long bone PTOM. While open bone biopsy and culture is considered the 'gold diagnostic standard,' its cost and invasiveness are often prohibitive and have prompted the search for alternate diagnostic methods. OBJECTIVE: To evaluate the sensitivity and specificity of various diagnostic modalities relative to open bone biopsy and culture for the detection of long bone PTOM...
May 25, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
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