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https://www.readbyqxmd.com/read/28934112/biological-mechanisms-by-which-antiproliferative-actions-of-resveratrol-are-minimized
#1
REVIEW
Yih Ho, Yu-Syuan Lin, Hsuan-Liang Liu, Ya-Jung Shih, Shin-Ying Lin, Ai Shih, Yu-Tang Chin, Yi-Ru Chen, Hung-Yun Lin, Paul J Davis
Preclinical and clinical studies have offered evidence for protective effects of various polyphenol-rich foods against cardiovascular diseases, neurodegenerative diseases, and cancers. Resveratrol is among the most widely studied polyphenols. However, the preventive and treatment effectiveness of resveratrol in cancer remain controversial because of certain limitations in existing studies. For example, studies of the activity of resveratrol against cancer cell lines in vitro have often been conducted at concentrations in the low μM to mM range, whereas dietary resveratrol or resveratrol-containing wine rarely achieve nM concentrations in the clinic...
September 21, 2017: Nutrients
https://www.readbyqxmd.com/read/28933917/grape-and-wine-polymeric-polyphenols-their-importance-in-enology
#2
Lingxi Li, Baoshan Sun
Phenolic compounds are important constituents of red wine, contributing to its sensory properties and antioxidant activity. Owing to the diversity and structural complexity, study of these compounds was mainly limited, during the last three decades, on their low-molecular-mass compounds or simple phenolic compounds. Only in recent years, much attention has been paid to highly polymerized polyphenols in grape and red wines. The reason for this is largely due to the development of analytical techniques, especially those of HPLC-ESI-MS, permitting the structural characterization of highly polymerized polyphenols...
September 21, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/28933773/rapid-quantification-of-major-volatile-metabolites-in-fermented-food-and-beverages-using-gas-chromatography-mass-spectrometry
#3
Farhana R Pinu, Silas G Villas-Boas
Here we present a method for the accurate quantification of major volatile metabolites found in different food and beverages, including ethanol, acetic acid and other aroma compounds, using gas chromatography coupled to mass spectrometry (GC-MS). The method is combined with a simple sample preparation procedure using sodium chloride and anhydrous ethyl acetate. The GC-MS analysis was accomplished within 4.75 min, and over 80 features were detected, of which 40 were positively identified using an in-house and a commercialmass spectrometry (MS) library...
July 26, 2017: Metabolites
https://www.readbyqxmd.com/read/28933753/recent-advances-in-plant-phenolics
#4
EDITORIAL
Daniel A Jacobo-Velázquez, Luis Cisneros-Zevallos
The scientific interest in plant phenolics as chemopreventive and therapeutic agents against chronic and degenerative diseases has been increasing since the late 1990s, when the French paradox was associated with the high intake of phenolics present in red wine [1]. [...].
July 26, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28933413/the-role-of-the-nrf2-are-antioxidant-system-in-preventing-cardiovascular-diseases
#5
REVIEW
Robert E Smith, Kevin Tran, Cynthia C Smith, Miranda McDonald, Pushkar Shejwalkar, Kenji Hara
It is widely believed that consuming foods and beverages that have high concentrations of antioxidants can prevent cardiovascular diseases and many types of cancer. As a result, many articles have been published that give the total antioxidant capacities of foods in vitro. However, many antioxidants behave quite differently in vivo. Some of them, such as resveratrol (in red wine) and epigallocatechin gallate or EGCG (in green tea) can activate the nuclear erythroid-2 like factor-2 (Nrf2) transcription factor...
November 11, 2016: Diseases (Basel)
https://www.readbyqxmd.com/read/28932179/non-invasive-real-time-monitoring-of-yeast-volatilome-by-ptr-tof-ms
#6
Iuliia Khomenko, Irene Stefanini, Luca Cappellin, Valentina Cappelletti, Pietro Franceschi, Duccio Cavalieri, Tilmann D Märk, Franco Biasioli
INTRODUCTION: Producing a wide range of volatile secondary metabolites Saccharomyces cerevisiae influences wine, beer, and bread sensory quality and hence selection of strains based on their volatilome becomes pivotal. A rapid on-line method for volatilome assessing of strains growing on standard solid media is still missing. OBJECTIVES: Methodologically, the aim of this study was to demonstrate the automatic, real-time, direct, and non-invasive monitoring of yeast volatilome in order to rapidly produce a robust large data set encompassing measurements relative to many strains, replicates and time points...
2017: Metabolomics: Official Journal of the Metabolomic Society
https://www.readbyqxmd.com/read/28931328/kinetic-and-thermodynamic-parameters-and-partial-characterization-of-the-crude-extract-of-tannase-produced-by-saccharomyces-cerevisiae-ccmb-520
#7
Lúzia Morgana de Melo Lopes, Larissa Hayannyelly Costa Batista, Marcos Juliano Gouveia, Tonny Cley Campos Leite, Marcelo Rodrigues Figueira de Mello, Sandra Aparecida de Assis, Amanda Reges de Sena
Tannase can be used in different industrial sectors such as in food (juices and wine) and pharmaceutical production (trimethoprim) because it catalyses the hydrolysis of hydrolysable tannins. The aim of the current study is to assess the tannase found in the crude extract of Saccharomyces cerevisiae CCMB 520, and to set its catalytic and thermodynamic properties. The enzyme was optimally active at pH 6.0 and temperature 30 °C. Tannase was activated by Na(+), Ca(2+), K(+) at 5 × 10(-3) mol/L. The half-life at 30 °C was 3465...
September 20, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28931168/socio-cultural-norms-and-roles-in-the-use-and-abuse-of-alcohol-among-members-of-a-rural-community-in-southeast-nigeria
#8
E N Nwagu, S I C Dibia, A N Odo
Social influences together with local cultural norms are central factors that can influence the use of alcohol. The study, therefore, identified socio-cultural norms and roles capable of influencing alcohol use among young people in an alcohol producing community, in Nigeria. We used qualitative technique - focused group discussions among selected key persons in the area of study. Three groups; adult males, adult females and youths were engaged in discussions around the themes of socio-cultural; norms, roles, beliefs, values and practices that influences alcohol abuse...
October 1, 2017: Health Education Research
https://www.readbyqxmd.com/read/28926461/nailfold-capillaroscopy-findings-mimicking-systemic-sclerosis-in-a-patient-with-port-wine-stain
#9
Serdar Can Güven, Özkan Varan, Hamit Küçük
No abstract text is available yet for this article.
September 19, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28925975/new-insights-into-the-genome-organization-of-yeast-killer-viruses-based-on-atypical-killer-strains-characterized-by-high-throughput-sequencing
#10
Manuel Ramírez, Rocío Velázquez, Antonio López-Piñeiro, Belén Naranjo, Francisco Roig, Carlos Llorens
Viral M-dsRNAs encoding yeast killer toxins share similar genomic organization, but no overall sequence identity. The dsRNA full-length sequences of several known M-viruses either have yet to be completed, or they were shorter than estimated by agarose gel electrophoresis. High-throughput sequencing was used to analyze some M-dsRNAs previously sequenced by traditional techniques, and new dsRNAs from atypical killer strains of Saccharomyces cerevisiae and Torulaspora delbrueckii. All dsRNAs expected to be present in a given yeast strain were reliably detected and sequenced, and the previously-known sequences were confirmed...
September 19, 2017: Toxins
https://www.readbyqxmd.com/read/28923549/color-stability-of-lithium-disilicate-ceramics-after-aging-and-immersion-in-common-beverages
#11
Eleni-Sotiria Palla, Eleana Kontonasaki, Nikolaos Kantiranis, Lambrini Papadopoulou, Triantafyllia Zorba, Konstantinos M Paraskevopoulos, Petros Koidis
STATEMENT OF PROBLEM: The color of an esthetic restoration and its color stability are important for long-term success. However, the impact of common beverages on lithium disilicate ceramic is not well known. PURPOSE: The purpose of this in vitro study was to investigate color variations of lithium disilicate ceramics after thermal cycling (TC) and immersion in commonly consumed beverages. MATERIAL AND METHODS: A total of 288 specimens (1×10×10 mm) were fabricated from IPS e-max computer-aided design (CAD) (n=72), IPS e-max CERAM ([CER] n=72), IPS e-max Press with glazing ([PG] n=72), and IPS e-max Press without glazing ([PNG] n=72) according to the manufacturer's instructions...
September 16, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28922915/influence-of-fermentation-temperature-yeast-strain-and-grape-juice-on-the-aroma-chemistry-and-sensory-profile-of-sauvignon-blanc-wines
#12
Rebecca Christina Deed, Bruno Fedrizzi, Richard C Gardner
Sauvignon blanc wine, balanced by herbaceous and tropical aromas, is fermented at low temperatures (10-15 °C). Anecdotal accounts from winemakers suggest that cold ferments produce and retain more 'fruity' aroma compounds; nonetheless, studies have not confirmed why low temperatures are optimal for Sauvignon blanc. Thirty-two aroma compounds were quantitated from two Marlborough Sauvignon blanc juices fermented at 12.5 °C and 25 °C, using Saccharomyces cerevisiae strains EC1118, L-1528, M2 and X5. Fourteen compounds were responsible for driving differences in aroma chemistry...
September 19, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28922393/a-set-of-nutrient-limitations-trigger-yeast-cell-death-in-a-nitrogen-dependent-manner-during-wine-alcoholic-fermentation
#13
Camille Duc, Martine Pradal, Isabelle Sanchez, Jessica Noble, Catherine Tesnière, Bruno Blondin
Yeast cell death can occur during wine alcoholic fermentation. It is generally considered to result from ethanol stress that impacts membrane integrity. This cell death mainly occurs when grape musts processing reduces lipid availability, resulting in weaker membrane resistance to ethanol. However the mechanisms underlying cell death in these conditions remain unclear. We examined cell death occurrence considering yeast cells ability to elicit an appropriate response to a given nutrient limitation and thus survive starvation...
2017: PloS One
https://www.readbyqxmd.com/read/28920164/purification-and-characterization-of-a-naringinase-from-cryptococcus-albidus
#14
Nataliya Borzova, Olena Gudzenko, Lyudmila Varbanets
Naringinase which was extracted from the fermented broth of Cryptococcus albidus was purified about 42-folds with yield 0.7% by sulfate fractionation and chromatography on Toyopearl HW-60, Fractogel DEAE-650-s, and Sepharose 6B columns. Molecular weight of protein determined by gel filtration and SDS-PAGE was 50 kDa. Naringinase of C. albidus includes high content of the dicarbonic and hydrophobic amino acids. Enzyme contains also carbohydrate component, represented by mannose, galactose, rhamnose, ribose, arabinose, xylose, and glucose...
September 18, 2017: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/28918636/soluble-protein-and-amino-acid-content-affects-the-foam-quality-of-sparkling-wine
#15
Bruna C Condé, Eloise Bouchard, Julie A Culbert, Kerry L Wilkinson, Sigfredo Fuentes, Kate S Howell
Proteins and amino acids are known to influence the foam characteristics of sparkling wines. However, it is unclear to what extent they promote foam formation and/or stability. This study aimed to investigate the effect of protein content and amino acid composition, measured via the bicinchoninic acid assay and high-performance liquid chromatography respectively, on the foaming properties of 28 sparkling white wines, made by different production methods. Foam volume and stability were determined using a robotic pourer and computer vision algorithms...
September 17, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28917786/chemometric-compositional-analysis-of-phenolic-compounds-in-fermenting-samples-and-wines-using-different-infrared-spectroscopy-techniques
#16
Jose Luis Aleixandre-Tudo, Helene Nieuwoudt, Jose Luis Aleixandre, Wessel du Toit
The wine industry requires reliable methods for the quantification of phenolic compounds during the winemaking process. Infrared spectroscopy appears as a suitable technique for process control and monitoring. The ability of Fourier transform near infrared (FT-NIR), attenuated total reflectance mid infrared (ATR-MIR) and Fourier transform infrared (FT-IR) spectroscopies to predict compositional phenolic levels during red wine fermentation and aging was investigated. Prediction models containing a large number of samples collected over two vintages from several industrial fermenting tanks as well as wine samples covering a varying number of vintages were validated...
January 1, 2018: Talanta
https://www.readbyqxmd.com/read/28915966/use-of-anthropogenic-nitrogen-fertilizers-in-agriculture-is-associated-with-per-capita-ethanol-consumption
#17
Keith Fluegge, Kyle Fluegge
It has previously been demonstrated that emissions of the agricultural pollutant, nitrous oxide (N2O), may be a confounder to the relationship between herbicide use and psychiatric impairments, including ADHD. This report attempts to extend this hypothesis by testing whether annual use of anthropogenic nitrogen-based fertilizers in U.S. agriculture (thought to be the most reliable indicator of environmental N2O emissions) is associated with per capita ethanol consumption patterns, a behavior often comorbid with ADHD...
September 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28915384/supramolecular-nano-sniffers-for-ultrasensitive-detection-of-formaldehyde
#18
Uchangi Satyaprasad Akshath, Praveena Bhatt
Supramolecular nanoparticle hybrids for biosensing of analytes have been a major focus due to their tunable optical and surface properties. Quantum dots-Gold nanoparticle (QDs-GNP) based FRET probes involving turn on/off principles have gained immense interest due to their specificity and sensitivity. Recent focus is on applying these supramolecular hybrids for enzyme operated biosensors that can specifically turn-on fluorescence induced by co-factor or product formed from enzymatic reaction. The present study focuses on locking and unlocking the interaction between QD-GNP pair leading to differential fluorescent properties...
September 9, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28915292/news-views-and-reviews-a-tool-for-my-laser-practice-i-simply-can-t-do-without-shining-a-light-on-my-favorite-light-source
#19
Eric F Bernstein
With laser surgery, what you see is what you get. Visualizing the target for treatment, be it a port-wine stain, a cluster of spider veins, a tattoo or freckles, or simply photodamaged skin requires seeing through surface reflections, dry skin, and often quite dark laser goggles. The tool that has been indispensable to me in my practice is the Syris v900L polarizing and magnifying headlamp. This indispensable tool makes laser treatment more precise, effective, and easier by truly shining a light on the subject of a laser treatment...
September 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28914660/mediterranean-diet-impact-on-cardiovascular-diseases-a-narrative-review
#20
Anna V Mattioli, Pasquale Palmiero, Olivia Manfrini, Paolo E Puddu, Savina Nodari, Alessandra Dei Cas, Giuseppe Mercuro, Domenico Scrutinio, Pietro Palermo, Susanna Sciomer, Simona Di Francesco, Giuseppina Novo, Salvatore Novo, Roberto F E Pedretti, Annapaola Zito, Gianfranco Parati, Roberto Pedrinelli, Alberto Farinetti, Maria Maiello, Federica Moscucci, Raffaele L Tenaglia, Vincenzo Sucato, Marco Triggiani, Lucia Cugusi, Pietro Scicchitano, Pier S Saba, Marco M Ciccone
: Cardiovascular disease (CVD) accounts for more than 17 million deaths per year worldwide. It has been estimated that the influence of lifestyle on CVD mortality amounts to 13.7% for smoking, 13.2% for poor diet, and 12% for inactive lifestyle. These results deeply impact both the healthy status of individuals and their skills in working. The impact of CVD on productivity loss accounts for the 24% in total costs for CVD management.Mediterranean diet (MedD) can positively impact on natural history of CVD. It is characterized by a relatively high consumption of inexpensive and genuine food such as cereals, vegetables, legumes, nuts, fish, fresh fruits, and olive oil as the principal source of fat, low meat consumption and low-to-moderate consumption of milk, dairy products, and wine...
September 12, 2017: Journal of Cardiovascular Medicine
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