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https://www.readbyqxmd.com/read/28538835/ghrelin-plasma-levels-gastric-ghrelin-cell-density-and-bone-mineral-density-in-women-with-rheumatoid-arthritis
#1
F A N Maksud, A M Kakehasi, M F B R Guimarães, C J Machado, A J A Barbosa
Generalized bone loss can be considered an extra-articular manifestation of rheumatoid arthritis (RA) that may lead to the occurrence of fractures, resulting in decreased quality of life and increased healthcare costs. The peptide ghrelin has demonstrated to positively affect osteoblasts in vitro and has anti-inflammatory actions, but the studies that correlate ghrelin plasma levels and RA have contradictory results. We aimed to evaluate the correlation between total ghrelin plasma levels, density of ghrelin-immunoreactive cells in the gastric mucosa, and bone mineral density (BMD) in twenty adult women with established RA with 6 months or more of symptoms (mean age of 52...
May 18, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/28538596/acute-and-hyper-acute-thoracolumbar-corpectomy-for-traumatic-burst-fractures-using-a-mini-open-lateral-approach
#2
William D Smith, Nick Ghazarian, Ginger Christian
STUDY DESIGN: Retrospective chart review. OBJECTIVE: The study purpose was to examine the feasibility of acute (<24 hours) and hyper-acute (<8 hours) treatment of thoracolumbar burst fractures to maintain or improve spinal injury scores. SUMMARY OF BACKGROUND DATA: Historically, treatment of spinal burst fractures within 24 hours from injury was considered an "acute" treatment timeframe. Patient polytrauma triage, multiple surgical specialty and hospital resource coordination affect time to treatment...
May 22, 2017: Spine
https://www.readbyqxmd.com/read/28538594/trends-in-patient-care-for-traumatic-spinal-injuries-in-the-united-states-a-national-inpatient-sample-study-of-the-correlations-with-patient-outcomes-from-2001-to-2012
#3
Christopher M Holland, Marcus D Mazur, Erica F Bisson, Meic H Schmidt, Andrew T Dailey
STUDY DESIGN: Retrospective database review OBJECTIVE.: To examine whether patient characteristics, distribution of care, and patient outcomes for spinal cord injury (SCI) in the United States have changed between 2001 and 2012. SUMMARY OF BACKGROUND DATA: Although patient outcomes after cranial injury are better at high-volume centers with specialized, multidisciplinary teams, similar assessments have not been done for spinal injuries. METHODS: We retrospectively reviewed the National and Nationwide Inpatient Samples for the years 2001, 2002, 2011, and 2012 to identify patients with spinal fracture with or without SCI...
May 22, 2017: Spine
https://www.readbyqxmd.com/read/28538576/the-effects-of-motorcycle-helmet-legislation-on-craniomaxillofacial-injuries
#4
Nicholas S Adams, Patrick A Newbury, Mitchell G Eichhorn, Alan T Davis, Robert J Mann, John W Polley, John A Girotto
BACKGROUND: Motorcycle helmet legislation has been a contentious topic for over a half-century. Benefits of helmet use in motorcycle trauma patients are well documented. In 2012, Michigan repealed its universal motorcycle helmet law in favor of a partial helmet law. The authors describe the early clinical effects on facial injuries throughout Michigan. METHODS: Retrospective data from the Michigan Trauma Quality Improvement Program trauma database were evaluated...
June 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28538539/pain-and-analgesia-requirements-with-hip-fracture-surgery
#5
Jamie AʼCourt, Deborah Lees, William Harrison, Thomas Ankers, Mike R Reed
BACKGROUND: Hip hemiarthroplasty and dynamic hip screw (DHS) fixation are common procedures performed in trauma units, but there is little information regarding perioperative pain experience with respect to these treatment modalities. PURPOSE: To evaluate the relationship between pain, analgesia requirements, and type of procedure for hip fracture surgery. METHODS: An analysis was performed on consecutive patients presenting with a hip fracture in 2 hospitals over 2 years...
May 2017: Orthopaedic Nursing
https://www.readbyqxmd.com/read/28538459/patient-comprehension-and-compliance-survey-to-assess-postoperative-pain-regimens-in-the-orthopaedic-trauma-population
#6
Anup K Gangavalli, Ajith Malige, Saqib Rehman, Chinenye O Nwachuku
OBJECTIVE: This study aims to determine the groups of patients who are at risk for noncompliance and misunderstanding of their pain regimen. DESIGN: Survey-based cohort study. SETTING: Suburban Level-I trauma center. PATIENTS/PARTICIPANTS: A total of 171 patients between the ages of 18-89 years who underwent surgical fixation of fractures involving the pelvis, long bones, or periarticular regions of the knee, ankle, elbow, and wrist...
June 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28538458/continuous-femoral-nerve-catheters-decrease-opioid-related-side-effects-and-increase-home-disposition-rates-among-geriatric-hip-fracture-patients
#7
Diren Arsoy, Michael J Gardner, Derek F Amanatullah, James I Huddleston, Stuart B Goodman, William J Maloney, Julius A Bishop
OBJECTIVE: To evaluate the effect of continuous femoral nerve catheter (CFNC) for postoperative pain control in geriatric proximal femur fractures compared with standard analgesia (SA) treatment. DESIGN: Retrospective comparative study. SETTING: Academic Level 1 trauma center. PATIENTS/PARTICIPANTS: We retrospectively identified 265 consecutive geriatric hip fracture patients who underwent surgical treatment. INTERVENTION: One hundred forty-nine patients were treated with standard analgesia without nerve catheter whereas 116 patients received an indwelling CFNC...
June 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28538456/social-to-moderate-alcohol-consumption-provides-a-protective-effect-for-functional-outcomes-after-fixation-of-orthopaedic-fractures
#8
Hesham Saleh, Adam Driesman, Nina Fisher, Philipp Leucht, Sanjit Konda, Kenneth Egol
OBJECTIVES: To identify the association between social and moderate alcohol consumption and functional outcomes after surgical management of orthopaedic fractures. DESIGN: Prospective cohort study. SETTING: Level 1 trauma center. PATIENTS/PARTICIPANTS: Seven hundred eighty-four patients who were operatively treated for an isolated orthopaedic fracture were prospectively followed. Patients were categorized into groups according to self-reported drinking frequencies based on NIAAA guidelines...
June 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28538455/operative-fixation-for-clavicle-fractures-socioeconomic-differences-persist-despite-overall-population-increases-in-utilization
#9
William W Schairer, Benedict U Nwachukwu, Russell F Warren, David M Dines, Lawrence V Gulotta
BACKGROUND: Clavicle fractures were traditionally treated conservatively, but recent evidence has shown improved outcomes with surgical management. The purpose of this study was to evaluate the recent trends in operative treatment of clavicle fractures, and to analyze for patient related factors that may affect treatment strategy. METHODS: The Healthcare Cost and Utilization Project (HCUP) California and Florida inpatient, outpatient, and the Emergency Department databases were used to identify all patients with clavicle fractures between 2005 and 2010...
June 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28538454/open-tibia-shaft-fractures-and-soft-tissue-coverage-the-effects-of-management-by-an-orthopaedic-microsurgical-team
#10
James VandenBerg, Daniel Osei, Martin I Boyer, Michael J Gardner, William M Ricci, Amanda Spraggs-Hughes, Christopher M McAndrew
OBJECTIVES: To compare the timing of soft-tissue (flap) coverage and occurrence of complications before and after the establishment of an integrated orthopaedic trauma/microsurgical team. DESIGN: Retrospective cohort study. SETTING: A single level 1 trauma center. PATIENTS: Twenty-eight subjects (13 pre- and 15 post-integration) with open tibia shaft fractures (OTA/AO 42A, 42B, and 42C) treated with flap coverage between January 2009 and March 2015...
June 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28538453/does-concurrent-tibial-intramedullary-nailing-and-fibular-fixation-increase-rates-of-tibial-nonunion-a-matched-cohort-study
#11
Michael Githens, Justin Haller, Julie Agel, Reza Firoozabadi
OBJECTIVES: To determine if there is a difference in rates of tibial nonunion in patients undergoing tibial intramedullary (IM) nailing and fibular fixation as compared to a matched cohort undergoing tibial IM nailing alone. DESIGN: Retrospective matched cohort study. SETTING: Single Level 1 academic trauma center. PATIENTS: Consecutive patients 18 years and older with a tibia and fibula fracture treated with tibial IM nailing and fibular fixation who were determined radiographically and clinically healed or had a minimum 1-year follow-up were included...
June 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28538452/proximal-femoral-shortening-after-cephalomedullary-nail-insertion-for-intertrochanteric-fractures
#12
Ron Gilat, Omri Lubovsky, Ehud Atoun, Ronen Debi, Ornit Cohen, Yoram A Weil
OBJECTIVE: To assess the incidence of proximal femoral shortening (PFS) and its effect on the patient outcomes when intertrochanteric fractures were treated with a cephalomedullary nail (CMN). DESIGN: Retrospective cohort study. SETTINGS: Level II trauma center. PATIENTS: Forty-eight consecutive patients with OTA/AO 31-A intertrochanteric fractures. INTERVENTION: All patients were treated with a Gamma3 CMN (Stryker, Kalamazoo, MI)...
June 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28538451/similar-anatomical-reduction-and-lower-complication-rates-with-the-sinus-tarsi-approach-compared-with-the-extended-lateral-approach-in-displaced-intra-articular-calcaneal-fractures
#13
Tim Schepers, Manouk Backes, Siem A Dingemans, Vincent M de Jong, Jan S K Luitse
OBJECTIVES: To investigate whether the sinus tarsi approach (STA) allows for a similar anatomical reduction of the posterior talocalcaneal facet as the extended lateral approach (ELA) and compare the rate of postoperative wound complications. DESIGN: Retrospective. SETTING: Level 1 trauma center. PATIENTS: All consecutive patients from 2012 to 2015 with a closed displaced intra-articular calcaneal fracture Sanders type II and III surgically treated with the ELA (N = 60) and the STA (N = 65)...
June 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28538416/case-report-of-2-sudden-deaths-after-surgery-for-bone-fracture-usefulness-of-immunohistochemical-analysis-of-coronary-artery-for-identifying-acute-myocardial-infarction
#14
Atsushi Kurata, Jun Nishida, Takashi Koyama, Tamotsu Miki, Hirotsugu Hashimoto, Kengo Yamamoto, Masahiko Kuroda
RATIONALE: Death following orthopedic surgery has become rare, but does occur. Acute myocardial infarction (AMI) can be a cause of such death, but diagnosis of AMI is often challenging, even by autopsy. PATIENT CONCERNS: We have recently experienced 2 cases of sudden death after bone fracture surgery, in which AMI and pulmonary thromboembolism were clinically suspected as causes of death. Case 1 was a 60-year-old male with a history of diabetes mellitus who died 7 days after surgery for Lisfranc dislocation fracture...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28538398/simultaneous-bilateral-midshaft-clavicle-fractures-with-unilateral-dislocation-of-the-acromioclavicular-joint-a-case-report
#15
Dong Dong, Mingyang Yu, Guishan Gu
RATIONALE: Simultaneous bilateral mid-clavicle fracture with unilateral dislocation of the acromioclavicular (AC) joint is an extremely rare injury combination. PATIENT CONCERNS: Herein, we report a case of polytrauma in a 42 years old female following a road traffic accident. DIAGNOSES: The radiographs showed the fractures in bilateral middle third of the clavicle and AC joint dislocation of left shoulder. INTERVENTIONS: The patient was treated with a 5-hole locking hook plate to stabilize the left AC joint and a shortly reconstruction plate to fix the left clavicle...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28538396/effects-of-teriparatide-versus-alendronate-for-treatment-of-postmenopausal-osteoporosis-a-meta-analysis-of-randomized-controlled-trials
#16
Ya-Kang Wang, Si-Qing Qin, Tao Ma, Wei Song, Ren-Qi Jiang, Jian-Bin Guo, Kun Li, Yu-Min Zhang
OBJECTIVES: Osteoporosis remains a clinical challenge. Teriparatide is an anabolic drug and alendronate is an antiresorptive agent; both are used in the treatment of osteoporosis. Comprehensive reviews investigating the comparative safety and efficacy of teriparatide versus alendronate are scarce. Therefore, we conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to evaluate the safety and efficacy of teriparatide versus alendronate for the treatment of postmenopausal osteoporosis...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28538384/efficacy-and-safety-of-intravenous-tranexamic-acid-administration-in-patients-undergoing-hip-fracture-surgery-for-hemostasis-a-meta-analysis
#17
Pei Zhang, Jinshan He, Yongchao Fang, Pengtao Chen, Yuan Liang, Jingcheng Wang
BACKGROUND: Patients undergoing hip fracture surgery frequently require blood transfusion. Tranexamic acid (TXA) has been widely used to decrease blood loss and transfusion rates in joint replacement surgery. Therefore, we conducted a meta-analysis to evaluate efficacy and safety of intravenous TXA administration in patients suffering from hip fractures. METHODS: Electronic databases were searched before December 2016 by 2 independent reviewers, including Cochrane Library, EMBASE, PubMed, Web of Science, the Chinese Biomedical Literature database, and the China National Knowledge Infrastructure databases...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28538372/detection-of-very-delayed-coronary-stent-fracture-using-a-novel-fluoroscopic-stent-visualization-technique-against-intravascular-ultrasound-a-case-series
#18
Feifei Yang, Liwei Zhang, Dangsheng Huang, Dong Shen, Yongjiang Ma, Minjun Xiong, Chunhong Zhang, Miao Tian
RATIONALE: Stent fracture has received increased concern as it may be an important risk factor for late stent failure, intravascular ultrasound (IVUS) is always recommended to confirm the diagnosis of stent fracture. StentBoost can detect stent fractures more easily due to the enhanced stent strut visibility, compared with coronary angiography (CAG). Few cases were reported to compare the advantages of StentBoost vis-à-vis IVUS in detecting stent fracture. PATIENT CONCERNS: We reported 3 cases that were confirmed the diagnosis of stent fracture by StentBoost, which were preliminarily suspected by angiography, including one case that lacked the IVUS evidence of stent fracture...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28538289/a-three-dimensional-analysis-of-the-fracture-planes-in-pediatric-lateral-humeral-condyle-fractures-for-image-based-pin-positioning-during-fixation
#19
Do Young Park, Jae Ho Cho, Doo-Hyung Lee, Wan-Sun Choi, Jun Young Bang, Xiang Yun Yin
OBJECTIVE: To determine the 3 dimensional morphology of pediatric lateral condylar physeal fractures using 3-dimensional computed tomography (3D-CT) and to identify optimal pin positions for percutaneous pinning. DESIGN: Prospective case series of consecutively treated patients SETTING:: Tertiary university hospital setting. PATIENTS: Preoperative 3D-CTs in pediatric surgical candidates diagnosed with lateral condylar physeal fractures INTERVENTION:: Closed reduction and percutaneous pinning was performed...
May 17, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28538288/the-trajectory-of-short-and-long-term-recovery-of-tibial-shaft-fractures-following-intramedullary-nail-fixation
#20
Sebastian J Ko, Peter J O'Brien, Pierre Guy, Henry M Broekhuyse, Piotr A Blachut, Kelly A Lefaivre
OBJECTIVE: To determine the trajectory of recovery following tibial shaft fracture treated with intramedullary nail over the first five years, and to evaluate the magnitude of the changes in functional outcome at various time intervals. DESIGN: Prospective cohort study. SETTING: A level 1 trauma center. PATIENTS/PARTICIPANTS: 132 patients with tibial shaft fracture (OTA 42-A,B,C) were enrolled into the Center's prospectively enrolled orthopaedic trauma database between January 2005 and February 2010...
May 17, 2017: Journal of Orthopaedic Trauma
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