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https://www.readbyqxmd.com/read/28820902/from-hospitalization-records-to-surveillance-the-use-of-local-patient-profiles-to-characterize-cholera-in-vellore-india
#1
Melissa S Cruz, Tania M AlarconFalconi, Meghan A Hartwick, Aishwarya Venkat, Hanna Y Ehrlich, Shalini Anandan, Honorine D Ward, Balaji Veeraraghavan, Elena N Naumova
Despite availability of high quality medical records, health care systems often do not have the resources or tools to utilize these data efficiently. Yet, hospital-based, laboratory-confirmed records may pave the way for building reliable surveillance systems capable of monitoring temporal trends of emerging infections. In this communication, we present a new tool to compress and visualize medical records with a local population profile (LPP) approach, which transforms information into statistically comparable patterns...
2017: PloS One
https://www.readbyqxmd.com/read/28820894/short-term-apparent-brain-tissue-changes-are-contributed-by-cerebral-blood-flow-alterations
#2
Qiu Ge, Wei Peng, Jian Zhang, Xuchu Weng, Yong Zhang, Thomas Liu, Yu-Feng Zang, Ze Wang
Structural MRI (sMRI)-identified tissue "growth" after neuropsychological training has been reported in many studies but the origins of those apparent tissue changes (ATC) still remain elusive. One possible contributor to ATC is brain perfusion since T1-weighted MRI, the tool used to identify ATC, is sensitive to perfusion-change induced tissue T1 alterations. To test the hypothetical perfusion contribution to ATC, sMRI data were acquired before and after short-term global and regional perfusion manipulations via intaking a 200 mg caffeine pill and performing a sensorimotor task...
2017: PloS One
https://www.readbyqxmd.com/read/28820571/comparison-of-spreading-depolarizations-in-the-motor-cortex-and-nucleus-accumbens-similar-patterns-of-oxygen-responses-and-the-role-of-dopamine
#3
Caddy Noahl Hobbs, Gordon Holzberg, Akira S Min, R Mark Wightman
Spreading depolarizations (SD) are pathophysiological phenomena that spontaneously arise in traumatized neural tissue and can promote cellular death. Most investigations of SD are performed in the cortex, a brain region that is susceptible to these depolarizing waves and accessible via a variety of monitoring techniques. Here, we describe SD responses in the cortex and the deep brain region of the nucleus accumbens (NAc) of the anesthetized rat with a minimally invasive, implantable sensor. With high temporal resolution, we characterize the time course of oxygen responses to SD in relation to the electrophysiological depolarization signal...
August 18, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/28819309/visualization-and-detection-of-ciliary-beating-pattern-and-frequency-in-the-upper-airway-using-phase-resolved-doppler-optical-coherence-tomography
#4
Joseph C Jing, Jason J Chen, Lidek Chou, Brian J F Wong, Zhongping Chen
Ciliary motion plays a critical role in the overall respiratory health of the upper airway. These cilia beat at a native frequency and in a synchronized pattern to continuously transport foreign particulate trapped in a layer of mucous out of the upper airway. Disruption of ciliary motion can lead to severe respiratory diseases and compromised respiratory function. Currently, the study of cilia requires expensive high speed cameras and high powered microscopes which is unsuitable for in vivo imaging and diagnosis...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28819293/effects-of-temporal-correlations-in-social-multiplex-networks
#5
Michele Starnini, Andrea Baronchelli, Romualdo Pastor-Satorras
Multi-layered networks represent a major advance in the description of natural complex systems, and their study has shed light on new physical phenomena. Despite its importance, however, the role of the temporal dimension in their structure and function has not been investigated in much detail so far. Here we study the temporal correlations between layers exhibited by real social multiplex networks. At a basic level, the presence of such correlations implies a certain degree of predictability in the contact pattern, as we quantify by an extension of the entropy and mutual information analyses proposed for the single-layer case...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28819115/genome-wide-identification-and-expression-profiling-of-long-non-coding-rnas-in-auditory-and-vestibular-systems
#6
Kathy Ushakov, Tal Koffler-Brill, Aviv Rom, Kobi Perl, Igor Ulitsky, Karen B Avraham
Mammalian genomes encode multiple layers of regulation, including a class of RNA molecules known as long non-coding RNAs (lncRNAs). These are >200 nucleotides in length and similar to mRNAs, they are capped, polyadenylated, and spliced. In contrast to mRNAs, lncRNAs are less abundant and have higher tissue specificity, and have been linked to development, epigenetic processes, and disease. However, little is known about lncRNA function in the auditory and vestibular systems, or how they play a role in deafness and vestibular dysfunction...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28818819/quantifying-human-movement-using-the-movn-smartphone-app-validation-and-field-study
#7
Ralph Maddison, Luke Gemming, Javier Monedero, Linda Bolger, Sarahjane Belton, Johann Issartel, Samantha Marsh, Artur Direito, Madeleine Solenhill, Jinfeng Zhao, Daniel John Exeter, Harshvardhan Vathsangam, Jonathan Charles Rawstorn
BACKGROUND: The use of embedded smartphone sensors offers opportunities to measure physical activity (PA) and human movement. Big data-which includes billions of digital traces-offers scientists a new lens to examine PA in fine-grained detail and allows us to track people's geocoded movement patterns to determine their interaction with the environment. OBJECTIVE: The objective of this study was to examine the validity of the Movn smartphone app (Moving Analytics) for collecting PA and human movement data...
August 17, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28818683/modeling-the-impact-of-latent-driving-patterns-on-traffic-safety-using-mobile-sensor-data
#8
Rajesh Paleti, Olcay Sahin, Mecit Cetin
Smartphones are now equipped with sensors capable of recording vehicle performance data at a very fine temporal resolution in a cost-effective way. In this paper, mobile sensor data from smartphones was used to identify and quantify unsafe driving patterns and their relationship with traffic crash incidences. Statistical models that account for measurement error associated with microscopic traffic measures computed using mobile sensor data were developed. The models with microscopic traffic measures were shown to be statistically better than traditional models that only control for roadway geometry and traffic exposure variables...
August 14, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28817805/ltp-at-hilar-mossy-cell-dentate-granule-cell-synapses-modulates-dentate-gyrus-output-by-increasing-excitation-inhibition-balance
#9
Yuki Hashimotodani, Kaoutsar Nasrallah, Kyle R Jensen, Andrés E Chávez, Daniel Carrera, Pablo E Castillo
Excitatory hilar mossy cells (MCs) in the dentate gyrus receive inputs from dentate granule cells (GCs) and project back to GCs locally, contralaterally, and along the longitudinal axis of the hippocampus, thereby establishing an associative positive-feedback loop and connecting functionally diverse hippocampal areas. MCs also synapse with GABAergic interneurons that mediate feed-forward inhibition onto GCs. Surprisingly, although these circuits have been implicated in both memory formation (e.g., pattern separation) and temporal lobe epilepsy, little is known about activity-dependent plasticity of their synaptic connections...
August 16, 2017: Neuron
https://www.readbyqxmd.com/read/28817215/unexpected-collective-larval-dispersal-but-little-support-for-sweepstakes-reproductive-success-in-the-highly-dispersive-brooding-mollusk-crepidula-fornicata
#10
Florentine Riquet, Thierry Comtet, Thomas Broquet, Frédérique Viard
In many marine invertebrates, long-distance dispersal is achieved during an extended pelagic larval phase. Although such dispersal should result in high gene flow over broad spatial scales, fine-scale genetic structure has often been reported, a pattern attributed to interfamilial variance in reproductive success and limited homogenization during dispersal. To examine this hypothesis, the genetic diversity of dispersing larvae must be compared with the post-dispersal stages, i.e. benthic recruits and adults...
August 17, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28815647/wildlife-disease-ecology-from-the-individual-to-the-population-insights-from-a-long-term-study-of-a-naturally-infected-european-badger-population
#11
Jenni L McDonald, Andrew Robertson, Matthew J Silk
1. Long-term individual-based datasets on host-pathogen systems are a rare and valuable resource for understanding the infectious disease dynamics in wildlife. A study of European badgers (Meles meles) naturally infected with bovine tuberculosis (bTB) at Woodchester Park in Gloucestershire (UK) has produced a unique dataset, facilitating investigation of a diverse range of epidemiological and ecological questions with implications for disease management. 2. Since the 1970s this badger population has been monitored with a systematic mark-recapture regime yielding a dataset of >15,000 captures of >3000 individuals, providing detailed individual life-history, morphometric, genetic, reproductive and disease data...
August 16, 2017: Journal of Animal Ecology
https://www.readbyqxmd.com/read/28815148/spatio-temporal-analysis-for-new-york-state-sparcs-data
#12
Xin Chen, Yu Wang, Elinor Schoenfeld, Mary Saltz, Joel Saltz, Fusheng Wang
Increased accessibility of health data provides unique opportunities to discover spatio-temporal patterns of diseases. For example, New York State SPARCS (Statewide Planning and Research Cooperative System) data collects patient level detail on patient demographics, diagnoses, services, and charges for each hospital inpatient stay and outpatient visit. Such data also provides home addresses for each patient. This paper presents our preliminary work on spatial, temporal, and spatial-temporal analysis of disease patterns for New York State using SPARCS data...
2017: AMIA Summits on Translational Science Proceedings
https://www.readbyqxmd.com/read/28815120/integrating-temporal-pattern-mining-in-ischemic-stroke-prediction-and-treatment-pathway-discovery-for-atrial-fibrillation
#13
Shijing Guo, Xiang Li, Haifeng Liu, Ping Zhang, Xin Du, Guotong Xie, Fei Wang
Atrial fibrillation (AF) is associated with an increased risk of acute ischemic stroke (AIS). Accurately predicting AIS and planning effective treatment pathways for AIS prevention are crucial for AF patients. Because of the temporality of patients' disease progressions, sequential disease and treatment patterns have the potential to improve risk prediction performance and contribute to effective treatment pathways. This paper integrates temporal pattern mining into the AF study of AIS prediction and treatment pathway discovery...
2017: AMIA Summits on Translational Science Proceedings
https://www.readbyqxmd.com/read/28814764/percolation-phase-transition-of-surface-air-temperature-networks-a-new-test-bed-for-el-ni%C3%A3-o-la-ni%C3%A3-a-simulations
#14
Lijuan Hua, Zhenghui Lu, Naiming Yuan, Lin Chen, Yongqiang Yu, Lu Wang
In this work, we studied the air-sea interaction over the tropical central eastern Pacific from a new perspective, climate network. The surface air temperatures over the tropical Pacific were constructed as a network, and the nodes within this network were linked if they have a similar temporal varying pattern. Using three different reanalysis datasets, we verified the percolation phase transition. That is, when the influences of El Niño/La Niña are strong enough to isolate more than 48% of the nodes, the network may abruptly be divided into many small pieces, indicating a change of the network state...
August 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28814392/temporal-eating-patterns-associations-with-nutrient-intakes-diet-quality-and-measures-of-adiposity
#15
Rebecca M Leech, Anna Timperio, Katherine M Livingstone, Anthony Worsley, Sarah A McNaughton
Background: Some evidence suggests that higher energy intake (EI) later in the day is associated with poor diet quality and obesity. However, EI at one eating occasion (EO) is also dependent on EI at surrounding EOs. Studies that examine the distribution of EOs across the day are rare.Objective: The aim of this study was to examine associations between temporal eating patterns, nutrient intakes, diet quality, and measures of adiposity in a representative sample of Australian adults.Design: Dietary data from two 24-h recalls collected during the cross-sectional 2011-2012 Australian National Nutrition and Physical Activity Survey were analyzed (n = 4544 adults, aged ≥19 y)...
August 16, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28814201/using-temporal-distancing-to-regulate-emotion-in-adolescence-modulation-by-reactive-aggression
#16
S P Ahmed, L H Somerville, C L Sebastian
Adopting a temporally distant perspective on stressors reduces distress in adults. Here we investigate whether the extent to which individuals project themselves into the future influences distancing efficacy. We also examined modulating effects of age across adolescence and reactive aggression: factors associated with reduced future-thinking and poor emotion regulation. Participants (N = 83, aged 12-22) read scenarios and rated negative affect when adopting a distant-future perspective, near-future perspective, or when reacting naturally...
August 17, 2017: Cognition & Emotion
https://www.readbyqxmd.com/read/28813491/climate-change-and-body-size-trends-in-aquatic-and-terrestrial-endotherms-does-habitat-matter
#17
Daniel E Naya, Hugo Naya, Joseph Cook
Several studies have claimed that reduction in body size comprises a nearly universal response to global warming; however, doubts about the validity of this pattern for endothermic species have been raised recently. Accordingly, we assessed temporal changes in body mass for 27 bird and 17 mammal species, to evaluate if a reduction in body size during the 20th century is a widespread phenomenon among endothermic vertebrates. In addition, we tested if there are differences in the temporal change in size between birds and mammals, aquatic and terrestrial species, and the first and second half of the 20th century...
2017: PloS One
https://www.readbyqxmd.com/read/28813490/low-validity-of-google-trends-for-behavioral-forecasting-of-national-suicide-rates
#18
Ulrich S Tran, Rita Andel, Thomas Niederkrotenthaler, Benedikt Till, Vladeta Ajdacic-Gross, Martin Voracek
Recent research suggests that search volumes of the most popular search engine worldwide, Google, provided via Google Trends, could be associated with national suicide rates in the USA, UK, and some Asian countries. However, search volumes have mostly been studied in an ad hoc fashion, without controls for spurious associations. This study evaluated the validity and utility of Google Trends search volumes for behavioral forecasting of suicide rates in the USA, Germany, Austria, and Switzerland. Suicide-related search terms were systematically collected and respective Google Trends search volumes evaluated for availability...
2017: PloS One
https://www.readbyqxmd.com/read/28813026/breath-figure-self-assembly-a-versatile-method-of-manufacturing-membranes-and-porous-structures-physical-chemical-and-technological-aspects
#19
REVIEW
Edward Bormashenko
The review is devoted to the physical, chemical, and technological aspects of the breath-figure self-assembly process. The main stages of the process and impact of the polymer architecture and physical parameters of breath-figure self-assembly on the eventual pattern are covered. The review is focused on the hierarchy of spatial and temporal scales inherent to breath-figure self-assembly. Multi-scale patterns arising from the process are addressed. The characteristic spatial lateral scales of patterns vary from nanometers to dozens of micrometers...
August 16, 2017: Membranes
https://www.readbyqxmd.com/read/28812976/learning-and-recognition-of-tactile-temporal-sequences-by-mice-and-humans
#20
Michael R Bale, Malamati Bitzidou, Anna Pitas, Leonie S Brebner, Lina Khazim, Stavros T Anagnou, Caitlin D Stevenson, Miguel Maravall
The world around us is replete with stimuli that unfold over time. When we hear an auditory stream like music or speech or scan a texture with our fingertip, physical features in the stimulus are concatenated in a particular order. This temporal patterning is critical to interpreting the stimulus. To explore the capacity of mice and humans to learn tactile sequences, we developed a task in which subjects had to recognise a continuous modulated noise sequence delivered to whiskers or fingertips, defined by its temporal patterning over hundreds of milliseconds...
August 16, 2017: ELife
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