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https://www.readbyqxmd.com/read/29692102/-soil-olsen-p-content-changing-trend-and-its-relationship-with-phosphorus-surplus-and-crop-yield-under-long-term-fertilization-in-loessial-soil-region-on-the-loess-plateau-china
#1
Sheng Zhe E, Zhi Qi Yang, Xi Bai Zeng, Ya Nan Wang, Zhao Xia Luo, Jin Hua Yuan, Zong Xian Che
The changing trend of soil available phosphorus (Olsen-P) content in soil and its relationship with soil phosphorus surplus and crop yield are fundamental when making appropriate phosphate fertilizer recommendations. In this paper, the influences of long-term fertilization on crops phosphorus uptake, soil phosphorus surplus, changing trend of soil available phosphorus content and relationships of soil available phosphorus content with soil phosphorus surplus and crop yield were investigated through 34 years (1981-2015) long-term trial in loessial soil region on the Loess Plateau...
November 2017: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
https://www.readbyqxmd.com/read/29691913/thiazoloisoindigo-a-building-block-that-merges-the-merits-of-thienoisoindigo-and-diazaisoindigo-for-conjugated-polymers
#2
Xiaobo Wan, Chenchen Li, Xiao Wang, Un Hio-Ieng, Jiawei Peng, Zhenggang Lan, Mian Cai, Jian Pei, Jieyu Wang
Thiazoloisoindigo, a novel structural variation of isoindigo, is for the first time utilized to synthesize conjugated polymers. Polymer based on thiazoloisoindigo merges the advantages of the one based on thienoisoindigo and diazaisoindigo: It not only exhibits a greatly red shifted UV-vis absorption to the near-infrared region due to its strong tendency to form quinoidal structures, similar to that based on thienoisoindigo, but also shows excellent ambipolar mobility (hole 3.93 and electron 1.07 cm2 V-1 s-1, respectively) in organic field-effect transistors (OFETs), superior than that based on diazaisoindigo, showing the strong electron-withdrawing capability of thiazoloisoindigo...
April 24, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29690560/detecting-inspection-objects-of-power-line-from-cable-inspection-robot-lidar-data
#3
Xinyan Qin, Gongping Wu, Jin Lei, Fei Fan, Xuhui Ye
Power lines are extending to complex environments (e.g., lakes and forests), and the distribution of power lines in a tower is becoming complicated (e.g., multi-loop and multi-bundle). Additionally, power line inspection is becoming heavier and more difficult. Advanced LiDAR technology is increasingly being used to solve these difficulties. Based on precise cable inspection robot (CIR) LiDAR data and the distinctive position and orientation system (POS) data, we propose a novel methodology to detect inspection objects surrounding power lines...
April 22, 2018: Sensors
https://www.readbyqxmd.com/read/29689757/color-disease-leaf-image-segmentation-using-nams-superpixel-algorithm
#4
Hua Li, Chuanbo Chen, Shengrong Zhao, Zehua Lyu
BACKGROUND: Disease leaf segmentation in color image is used to explore the disease shape and lesion regions. It is of great significance for pathological diagnosis and pathological research. OBJECTIVE: This paper proposes a superpixel algorithm using Non-symmetry and Anti-packing Model with Squares (NAMS) for color image segmentation of leaf disease. METHODS: First of all, the NAMS model is presented for color leaf disease image representation...
April 10, 2018: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/29688851/role-of-genetic-introgression-during-the-evolution-of-cultivated-rice-oryza-sativa-l
#5
Peter Civáň, Terence A Brown
BACKGROUND: Models for the origins of cultivated rice currently fall into two groups: ones that identify independent domestications of the indica, japonica and possibly also the aus types, and others that propose that the domestication phenotype was initially acquired by japonica, the underlying alleles then transferred by introgression to other pre-domesticated populations, giving the indica and aus varieties. Identifying the impact of past gene flow on cultivated rice genomes is therefore crucial to distinguishing between these models and understanding the domestication history of rice...
April 23, 2018: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/29688842/partial-arm-translocations-in-evolution-of-malaria-mosquitoes-revealed-by-high-coverage-physical-mapping-of-the-anopheles-atroparvus-genome
#6
Gleb N Artemov, Semen M Bondarenko, Anastasia N Naumenko, Vladimir N Stegniy, Maria V Sharakhova, Igor V Sharakhov
BACKGROUND: Malaria mosquitoes have had a remarkable stability in the number of chromosomes in their karyotype (2n = 6) during 100 million years of evolution. Moreover, autosomal arms were assumed to maintain their integrity even if their associations with each other changed via whole-arm translocations. Here we use high-coverage comparative physical genome mapping of three Anopheles species to test the extent of evolutionary conservation of chromosomal arms in malaria mosquitoes...
April 23, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29688724/single-stranded-condensation-stochastically-blocks-g-quadruplex-assembly-in-human-telomeric-rna
#7
Irene Gutiérrez, Miguel Garavís, Sara de Lorenzo, Alfredo Villasante, Carlos González, Jose Ricardo Arias-Gonzalez
TERRA is an RNA molecule transcribed from human subtelomeric regions towards chromosome ends potentially involved in regulation of heterochromatin stability, semiconservative replication and telomerase inhibition, among others. TERRA contains tandem repeats of the sequence GGGUUA, with a strong tendency to fold into a four-stranded arrangement known as parallel G-quadruplex. Here, we demonstrate by using single-molecule force spectroscopy that this potential is limited by the inherent capacity of RNA to self-associate randomly and further condense into entropically more favorable structures...
April 24, 2018: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/29688595/tetrachlorinated-polycyclic-aromatic-dicarboximides-new-electron-poor-%C3%AE-scaffolds-and-nir-emitters-by-palladium-catalyzed-annulation-reaction
#8
Magnus Mahl, Kazutaka Shoyama, Jessica Rühe, Vincenzo Grande, Frank Würthner
Herein we report a palladium-catalyzed annulation reaction consisting of a Suzuki-Miyaura cross-coupling and a C-H arylation cascade for the synthesis of tetrachlorinated polycyclic aromatic dicarboximides (PADIs). This convergent synthetic route afforded a broad series of hitherto unknown electron-deficient PADIs under optimized reaction conditions by coupling of a dibromo-tetrachloro-perylene dicarboximide with different polycyclic aromatic hydrocarbon (PAH) boronic acid pinacol esters in up to 89% yields...
April 24, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29687231/the-binding-of-an-anti-pd-1-antibody-to-fc%C3%AE-r%C3%AE-has-a-profound-impact-on-its-biological-functions
#9
Tong Zhang, Xiaomin Song, Lanlan Xu, Jie Ma, Yanjuan Zhang, Wenfeng Gong, Yilu Zhang, Xiaosui Zhou, Zuobai Wang, Yali Wang, Yingdi Shi, Huichen Bai, Ning Liu, Xiaolong Yang, Xinxin Cui, Yanping Cao, Qi Liu, Jing Song, Yucheng Li, Zhiyu Tang, Mingming Guo, Lai Wang, Kang Li
Antibodies targeting PD-1 have been demonstrated durable anti-cancer activity in certain cancer types. However, the anti-PD-1 antibodies are less or not efficacious in many situations, which might be attributed to co-expression of multiple inhibitory receptors or presence of immunosuppressive cells in the tumor microenvironment. Most of the anti-PD-1 antibodies used in clinical studies are of IgG4 isotype with the S228P mutation (IgG4S228P ). The functional impact by the interaction of anti-PD-1 IgG4S228P antibody with Fc gamma receptors (FcγRs) is poorly understood...
April 23, 2018: Cancer Immunology, Immunotherapy: CII
https://www.readbyqxmd.com/read/29685158/ebolavirus-diagnosis-made-simple-comparable-and-faster-than-molecular-detection-methods-preparing-for-the-future
#10
Ameh S James, Shawn Todd, Nina M Pollak, Glenn A Marsh, Joanne Macdonald
BACKGROUND: The 2014/2015 Ebolavirus outbreak resulted in more than 28,000 cases and 11,323 reported deaths, as of March 2016. Domestic transmission of the Guinea strain associated with the outbreak occurred mainly in six African countries, and international transmission was reported in four countries. Outbreak management was limited by the inability to rapidly diagnose infected cases. A further fifteen countries in Africa are predicted to be at risk of Ebolavirus outbreaks in the future as a consequence of climate change and urbanization...
April 23, 2018: Virology Journal
https://www.readbyqxmd.com/read/29684857/microrna-449a-functions-as-a-tumor-suppressor-in-pancreatic-cancer-by-the-epigenetic-regulation-of-atdc-expression
#11
Feng Li, Jing Liang, Lu Bai
A growing body of evidence has suggested that microRNAs (miRNAs) play a pivotal role in the development and progression of pancreatic cancer. miRNA-449a (miR-449a) has attracted particular interest due to its critical role in regulating cancer biology in numerous cancer types. However, whether miR-449a is involved in the regulation of pancreatic cancer development and progression remains unknown. In this study, we aimed to investigate the expression pattern and potential biological function of miR-449a in pancreatic cancer...
April 20, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29681422/spectral-analysis-of-ultrasound-radiofrequency-backscatter-for-the-detection-of-intercostal-blood-vessels
#12
Jon D Klingensmith, Asher Haggard, Russell J Fedewa, Beidi Qiang, Kenneth Cummings, Sean DeGrande, D Geoffrey Vince, Hesham Elsharkawy
Spectral analysis of ultrasound radiofrequency backscatter has the potential to identify intercostal blood vessels during ultrasound-guided placement of paravertebral nerve blocks and intercostal nerve blocks. Autoregressive models were used for spectral estimation, and bandwidth, autoregressive order and region-of-interest size were evaluated. Eight spectral parameters were calculated and used to create random forests. An autoregressive order of 10, bandwidth of 6 dB and region-of-interest size of 1.0 mm resulted in the minimum out-of-bag error...
April 19, 2018: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29680885/spatial-distribution-of-uranium-and-basic-water-quality-parameter-in-the-capital-of-bihar-and-consequent-ingestion-dose
#13
Deepak Kumar, Anshuman Singh, Rishi Kumar Jha
Investigation of presence of Uranium (U) in groundwater/drinking water is an active are of research due to its chemical and radiological toxicity as well as long-term health effects. The current study had the objective of estimating U as a naturally occurring radioactive element in groundwater samples and assessment of ingestion dose, when groundwater is the source of drinking water. The random sampling method was chosen for the collection of samples based on population density. The estimation of U was done using LED fluorimeter...
April 21, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29680003/the-comparative-effectiveness-of-quadratus-lumborum-blocks-and-paravertebral-blocks-in-radical-cystectomy-patients
#14
Austin J Lee, Jonathan G Yabes, Nathan Hale, Ronald L Hrebinko, Jeffrey R Gingrich, Jodi K Maranchie, Mina M Fam, Robert M Turner I I, Benjamin J Davies, Bruce Ben-David, Bruce L Jacobs
INTRODUCTION: Multimodal analgesia is an effective way to control pain and limit opioid use after surgery. The quadratus lumborum block and paravertebral block are two regional anesthesia techniques that leverage multimodal analgesia to improve postoperative pain control. We sought to compare the efficacy of these blocks for pain management following radical cystectomy. MATERIALS AND METHODS: We performed a retrospective review of radical cystectomy patients who received bilateral continuous paravertebral blocks (n = 125) or bilateral single shot quadratus lumborum blocks (n = 50) between 2014-2016...
April 2018: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29679696/effect-of-neuromonitor-guided-titrated-care-on-brain-tissue-hypoxia-after-opioid-overdose-cardiac-arrest
#15
Jonathan Elmer, Katharyn L Flickinger, Maighdlin W Anderson, Allison Koller, Matthew Sundermann, Cameron Dezfulian, David O Okonkwo, Lori A Shutter, David Salcido, Clifton W Callaway, James J Menegazzi
INTRODUCTION: Brain tissue hypoxia may contribute to preventable secondary brain injury after cardiac arrest. We developed a porcine model of opioid overdose cardiac arrest and post-arrest care including invasive, multimodal neurological monitoring of regional brain physiology. We hypothesized brain tissue hypoxia is common with usual post-arrest care and can be prevented by modifying mean arterial pressure (MAP) and arterial oxygen concentration (PaO2 ). METHODS: We induced opioid overdose and cardiac arrest in sixteen swine, attempted resuscitation after 9 minutes of apnea, and randomized resuscitated animals to three alternating 6-hour blocks of standard or titrated care...
April 18, 2018: Resuscitation
https://www.readbyqxmd.com/read/29679647/a-new-micro-holder-device-for-local-drug-delivery-during-in-vivo-whole-cell-recordings
#16
María Sáez, Maya Ketzef, Javier Alegre-Cortés, Ramón Reig, Gilad Silberberg
Focal administration of pharmacological agents during in vivo recordings is a useful technique to study the functional properties of neural microcircuits. However, the lack of visual control makes this task difficult and inaccurate, especially when targeting small and deep regions where spillover to neighboring regions is likely to occur. An additional problem with recording stability arises when combining focal drug administration with in vivo intracellular recordings, which are highly sensitive to mechanical vibrations...
April 18, 2018: Neuroscience
https://www.readbyqxmd.com/read/29679004/the-linc01138-drives-malignancies-via-activating-arginine-methyltransferase-5-in-hepatocellular-carcinoma
#17
Zhe Li, Jiwei Zhang, Xinyang Liu, Shengli Li, Qifeng Wang, Di Chen, Zhixiang Hu, Tao Yu, Jie Ding, Jinjun Li, Ming Yao, Jia Fan, Shenglin Huang, Qiang Gao, Yingjun Zhao, Xianghuo He
Recurrent chromosomal aberrations have led to the discovery of oncogenes or tumour suppressors involved in carcinogenesis. Here we characterized an oncogenic long intergenic non-coding RNA in the frequent DNA-gain regions in hepatocellular carcinoma (HCC), LINC01138 (long intergenic non-coding RNA located on 1q21.2). The LINC01138 locus is frequently amplified in HCC; the LINC01138 transcript is stabilized by insulin like growth factor-2 mRNA-binding proteins 1/3 (IGF2BP1/IGF2BP3) and is associated with the malignant features and poor outcomes of HCC patients...
April 20, 2018: Nature Communications
https://www.readbyqxmd.com/read/29678518/pattern-recognition-receptors-mediate-pro-inflammatory-effects-of-extracellular-mitochondrial-transcription-factor-a-tfam
#18
Stephanie M Schindler, Matthew G Frank, Jessica L Annis, Steven F Maier, Andis Klegeris
Neuroinflammation is a common pathogenic mechanism for a number of neurodegenerative disorders including Alzheimer's and Parkinson's diseases. Microglia, the immune cells of the brain, contribute to the onset and progression of the neuroinflammation observed in these diseases. Microglia become activated and initiate an inflammatory response by interacting with a diverse set of molecules, including the group of endogenous proteins released upon cell damage, termed damage-associated molecular patterns (DAMPs)...
April 17, 2018: Molecular and Cellular Neurosciences
https://www.readbyqxmd.com/read/29678208/glial-interleukin-1%C3%AE-upregulates-neuronal-sodium-channel-1-7-in-trigeminal-ganglion-contributing-to-temporomandibular-joint-inflammatory-hypernociception-in-rats
#19
Peng Zhang, Rui-Yun Bi, Ye-Hua Gan
BACKGROUND: The proinflammatory cytokine interleukin-1β (IL-1β) drives pain by inducing the expression of inflammatory mediators; however, its ability to regulate sodium channel 1.7 (Nav1.7), a key driver of temporomandibular joint (TMJ) hypernociception, remains unknown. IL-1β induces cyclooxygenase-2 (COX-2) and prostaglandin E2 (PGE2). We previously showed that PGE2 upregulated trigeminal ganglionic Nav1.7 expression. Satellite glial cells (SGCs) involve in inflammatory pain through glial cytokines...
April 20, 2018: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/29677513/nuclear-import-receptor-inhibits-phase-separation-of-fus-through-binding-to-multiple-sites
#20
Takuya Yoshizawa, Rustam Ali, Jenny Jiou, Ho Yee Joyce Fung, Kathleen A Burke, Seung Joong Kim, Yuan Lin, William B Peeples, Daniel Saltzberg, Michael Soniat, Jordan M Baumhardt, Rudolf Oldenbourg, Andrej Sali, Nicolas L Fawzi, Michael K Rosen, Yuh Min Chook
Liquid-liquid phase separation (LLPS) is believed to underlie formation of biomolecular condensates, cellular compartments that concentrate macromolecules without surrounding membranes. Physical mechanisms that control condensate formation/dissolution are poorly understood. The RNA-binding protein fused in sarcoma (FUS) undergoes LLPS in vitro and associates with condensates in cells. We show that the importin karyopherin-β2/transportin-1 inhibits LLPS of FUS. This activity depends on tight binding of karyopherin-β2 to the C-terminal proline-tyrosine nuclear localization signal (PY-NLS) of FUS...
April 19, 2018: Cell
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