Ryo Otani, Kazumoto Shibuya, Toshio Shimizu, Takamasa Kitaoji, Yu-Ichi Noto, Kota Bokuda, Hideki Kimura, Tomoki Suichi, Keigo Nakamura, Hiroki Kano, Marie Morooka, Yuya Aotsuka, Moeko Ogushi, Sonoko Misawa, Satoshi Kuwabara
Objective : This study aimed to reveal the diagnostic utility of Gold Coast (GC) criteria in Japanese patients with amyotrophic lateral sclerosis (ALS) by comparing the sensitivity/specificity with revised El Escorial (R-EE) and Awaji criteria, because its utility has not been studied in Asian ALS. Methods : Consecutive 639 patients (529 with ALS and 110 with ALS mimics), who were suspected of ALS and referred to three Japanese ALS centers, were enrolled. Diagnostic accuracy and characteristics of false positive and negative in GC criteria were compared with those of the Awaji and R-EE criteria...
January 16, 2024: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration