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Caffeine ingestion

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https://www.readbyqxmd.com/read/29317921/baseline-knowledge-of-potential-pet-toxins-a-survey-of-pharmacists
#1
Natalie W Young, Kenneth D Royal, Gigi S Davidson
Background: Consumer expenditures on their family pets are rapidly increasing, part of which can be attributed to prescription and OTC medications. In turn, community pharmacies are seeking and receiving an increased number of prescriptions for animals. Community pharmacists' ability to safely care for animal patients is relatively unexplored. Human medications, their normal dosing and even medication excipients could be lethal in some animal patients. Objective: The overarching objective of this study was to assess pharmacists' baseline knowledge of potential pet poisons...
October 2017: Pharmacy Practice
https://www.readbyqxmd.com/read/29273820/effects-of-caffeine-on-reaction-time-are-mediated-by-attentional-rather-than-motor-processes
#2
Christopher W N Saville, H M de Morree, Neil M Dundon, S M Marcora, C Klein
BACKGROUND: Caffeine has a well-established effect on reaction times (RTs) but the neurocognitive mechanisms underlying this are unclear. METHODS: In the present study, 15 female participants performed an oddball task after ingesting caffeine or a placebo, and electroencephalographic data were obtained. Single-trial P3b latencies locked to the stimulus and to the response were extracted and mediation models were fitted to the data to test whether caffeine's effect on RTs was mediated by its effect on either type of P3b latencies...
December 23, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/29262272/effects-of-carbohydrate-mouth-rinse-and-caffeine-on-high-intensity-interval-running-in-a-fed-state
#3
Simon Devenney, Shane Mangan, Marcus Shortall, Kieran Collins
The current study aims to identify if mouth rinsing with a 6% carbohydrate solution (CMR) and mouth rinsing and ingestion of caffeine (CMR+CAFF) can affect exercise performance during steady state (SS) running and high intensity intervals (HIT) in comparison to a 0% control solution (PLA), when in a fed state. Eight recreationally trained males completed three trials (CMR, CMR + CAFF, and PLA) of 45-min SS run and a HIT protocol (90% peak treadmill velocity) until fatigue in a double blinded, repeated measures study...
December 20, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29251842/taurine-caffeine-and-energy-drinks-reviewing-the-risks-to-the-adolescent-brain
#4
REVIEW
Christine Perdan Curran, Cecile A Marczinski
Energy drinks are emerging as a major component of the beverage market with sales projected to top $60 billion globally in the next five years. Energy drinks contain a variety of ingredients, but many of the top-selling brands include high doses of caffeine and the amino acid taurine. Energy drink consumption by children has raised concerns, due to potential caffeine toxicity. An additional risk has been noted among college-aged consumers of energy drinks who appear at higher risk of over-consumption of alcohol when the two drinks are consumed together...
December 1, 2017: Birth defects research
https://www.readbyqxmd.com/read/29247343/a-caffeine-maltodextrin-mouth-rinse-counters-mental-fatigue
#5
Jeroen Van Cutsem, Kevin De Pauw, Samuele Marcora, Romain Meeusen, Bart Roelands
INTRODUCTION: Mental fatigue is a psychobiological state caused by prolonged periods of demanding cognitive activity that has negative implications on many aspects in daily life. Caffeine and carbohydrate ingestion have been shown to be able to reduce these negative effects of mental fatigue. Intake of these substances might however be less desirable in some situations (e.g., restricted caloric intake, Ramadan). Rinsing caffeine or glucose within the mouth has already been shown to improve exercise performance...
December 15, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/29238244/influence-of-a-thermogenic-dietary-supplement-on-safety-markers-body-composition-energy-expenditure-muscular-performance-and-hormone-concentrations-a-randomized-placebo-controlled-double-blind-trial
#6
Grant M Tinsley, Stacie Urbina, Jacy Mullins, Jordan Outlaw, Sara Hayward, Matt Stone, Cliffa Foster, Colin Wilborn, Lem Taylor
Dietary supplementation is commonly employed by individuals seeking to improve body composition and exercise performance. The purpose of the present study was to examine the safety and effectiveness of a commercially available dietary supplement designed to promote thermogenesis and fat loss. In a randomized double-blind trial, participants were assigned to consume placebo or a multi-ingredient supplement containing caffeine, green tea extract, l-carnitine, evodiamine and other ingredients that purportedly enhance thermogenesis...
December 2017: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/29214920/caffeine-effects-on-vo2max-test-outcomes-investigated-by-a-placebo-perceived-as-caffeine-design
#7
Cayque Brietzke, Ricardo Yukio Asano, Felipe De Russi de Lima, Fabiano Aparecido Pinheiro, Franco-Alvarenga, Carlos Ugrinowitsch, Flávio Oliveira Pires
BACKGROUND: Ergogenic effects of caffeine (CAF) ingestion have been observed in different cycling exercise modes, and have been associated with alterations in ratings of perceived exertion (RPE). However, there has been little investigation of maximal oxygen uptake (VO2MAX) test outcomes. AIM: This study aimed to verify whether CAF may reduce RPE, thereby improving maximal incremental test (MIT) outcomes such as VO2MAX, time to exhaustion and peak power output (WPEAK)...
December 2017: Nutrition and Health
https://www.readbyqxmd.com/read/29209154/effects-of-two-pre-workout-supplements-on-concentric-and-eccentric-force-production-during-lower-body-resistance-exercise-in-males-and-females-a-counterbalanced-double-blind-placebo-controlled-trial
#8
Grant M Tinsley, Matthew A Hamm, Amy K Hurtado, Austin G Cross, Jose G Pineda, Austin Y Martin, Victor A Uribe, Ty B Palmer
Background: Pre-workout supplements purportedly enhance feelings of energy, reduce fatigue and improve exercise performance. The purpose of this study was to examine the performance effects of caffeinated and non-caffeinated multi-ingredient pre-workout supplements. Methods: In a counterbalanced, double-blind, placebo-controlled design, eccentric and concentric force production during lower body resistance exercise on a mechanized squat device were assessed after supplement ingestion...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/29204368/beneficial-effects-of-oral-pure-caffeine-on-oxidative-stress
#9
Daniela Metro, Valeria Cernaro, Domenico Santoro, Mattia Papa, Michele Buemi, Salvatore Benvenga, Luigi Manasseri
Ingestion of coffee (which is a mixture of over 1000 hydrosoluble substances) is known to protect from type-2 diabetes mellitus and its complications, and other chronic disorders associated with increased oxidative damage in blood and tissues. This protection is generally attributed to polyphenols and melanoidins. Very few studies were conducted on the amelioration of classic blood markers of oxidative stress induced after a few days of caffeine administration, but results vary. To assess whether caffeine per se could account for antioxidant properties of coffee in the short-term, we tested the ability of pure caffeine ingestion (5 mg/kg body weight/day in two daily doses for seven consecutive days) to improve plasma levels of six biochemical indices in healthy male volunteers (n = 15)...
December 2017: Journal of Clinical & Translational Endocrinology
https://www.readbyqxmd.com/read/29203963/ingestion-of-green-tea-with-lowered-caffeine-improves-sleep-quality-of-the-elderly-via-suppression-of-stress
#10
Keiko Unno, Shigenori Noda, Yohei Kawasaki, Hiroshi Yamada, Akio Morita, Kazuaki Iguchi, Yoriyuki Nakamura
Epidemiological and animal studies have demonstrated that ingestion of green tea enhances healthy life. However, caffeine in green tea can interfere with sleep. In this report, we examined the effect of green tea with lowered caffeine, low-caffeine green tea, on stress and sleep of the elderly. The participants (n = 10, mean age 89.3 ± 4.2 years) drank five cups/day of standard green tea for 1 week. Subsequently, they drank five cups/day of low-caffeine green tea for 2 weeks. Salivary α-amylase activity (sAA) was measured as a stress marker...
November 2017: Journal of Clinical Biochemistry and Nutrition
https://www.readbyqxmd.com/read/29199789/caffeine-acute-static-stretching-and-maximum-knee-flexion-strength
#11
Tyler M Farney, Arnold G Nelson, Joke Kokkonen
BACKGROUND: Reductions in one repetition maximum lifts (1RM) following static stretching can be attributed to enhanced neural inhibition, which can be reduced by using stimulants like caffeine. This study compared knee-flexion 1RM following either static stretching (SS) or no-stretching (NS), as well as after ingesting either caffeine (C) or placebo (P). METHODS: Twenty-four participants (12 female, 12 male) performed four random counterbalanced knee flexion 1RM tests...
December 1, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/29177579/disagreement-between-splenic-switch-off-and-myocardial-t1-mapping-after-caffeine-intake
#12
Dirkjan Kuijpers, Randy van Dijk, Marly van Assen, Theodorus A M Kaandorp, Paul R M van Dijkman, Rozemarijn Vliegenthart, Pim van der Harst, Matthijs Oudkerk
Caffeine is an adenosine receptor antagonist and a possible cause of inadequate stress perfusion. Splenic switch-off (SSO) and splenic rest-stress T1-mapping have been proposed as indicators of stress adequacy during perfusion cardiac magnetic resonance (CMR). We compared myocardial rest-stress T1-mapping with SSO and splenic rest-stress T1-mapping in patients with and without recent coffee intake. We analyzed 344 consecutive patients suspected of myocardial ischemia with adenosine perfusion CMR. All 146 normal CMR studies with a normal T1-rest of the myocardium, used as standard of reference, were included and divided in two groups...
November 24, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29140142/coffee-ingestion-enhances-one-mile-running-race-performance
#13
Neil D Clarke, Darren L Richardson, James Thie, Richard Taylor
PURPOSE: Caffeine, often in the form of coffee, is frequently supplemented by athletes in an attempt to facilitate improved performance during exercise. The aim of the present study was to investigate the effectiveness of coffee ingestion as an ergogenic aid prior to a one-mile (1609 m) race. METHODS: In a double-blind, randomised, crossover, placebo-controlled design 13 trained male runners completed a one-mile race 60 minutes following the ingestion of 0.09 g·kg(-1) coffee (COF), 0...
November 15, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29134560/neurochemical-and-neurotoxic-effects-of-mdma-ecstasy-and-caffeine-after-chronic-combined-administration-in-mice
#14
Anna Maria Górska, Katarzyna Kamińska, Agnieszka Wawrzczak-Bargieła, Giulia Costa, Micaela Morelli, Ryszard Przewłocki, Grzegorz Kreiner, Krystyna Gołembiowska
MDMA (3,4-methylenedioxymethamphetamine) is a psychostimulant popular as a recreational drug because of its effect on mood and social interactions. MDMA acts at dopamine (DA) transporter (DAT) and serotonin (5-HT) transporter (SERT) and is known to induce damage of dopamine and serotonin neurons. MDMA is often ingested with caffeine. Caffeine as a non-selective adenosine A1/A2A receptor antagonist affects dopaminergic and serotonergic transmissions. The aim of the present study was to determine the changes in DA and 5-HT release in the mouse striatum induced by MDMA and caffeine after their chronic administration...
November 13, 2017: Neurotoxicity Research
https://www.readbyqxmd.com/read/29124988/extracorporeal-elimination-of-butalbital-in-acute-aspirin-butalbital-caffeine-codeine-fiorinal-with-codeine-poisoning
#15
Janelle O Poyant, Robert Albright, Jeremy Clain, Govind Pandompatam, Erin F Barreto
BACKGROUND: Butalbital is a small molecule (approximately 220 Da), with 26% protein binding, a 0.8 L/kg volume of distribution, and is eliminated nearly 80% unchanged in the urine. Although hemodialysis has been used to treat overdoses of other barbiturates, the extracorporeal clearance of butalbital is unknown. The objective of this case is to describe the use of extracorporeal therapy to augment elimination of butalbital after an overdose of aspirin 325 mg-butalbital 50 mg-caffeine 40 mg with codeine 30 mg (Fiorinal with Codeine)...
November 10, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/29122414/the-effect-of-hydration-on-voice-quality-in-adults-a-systematic-review
#16
REVIEW
Maxine Alves, Esedra Krüger, Bhavani Pillay, Kristiane van Lierde, Jeannie van der Linde
OBJECTIVES: We aimed to critically appraise scientific, peer-reviewed articles, published in the past 10 years on the effects of hydration on voice quality in adults. STUDY DESIGN: This is a systematic review. METHODS: Five databases were searched using the key words "vocal fold hydration", "voice quality", "vocal fold dehydration", and "hygienic voice therapy". The Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines were followed...
November 6, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29113930/bitter-taste-responses-of-gustducin-positive-taste-cells-in-mouse-fungiform-and-circumvallate-papillae
#17
Ryusuke Yoshida, Shingo Takai, Keisuke Sanematsu, Robert F Margolskee, Noriatsu Shigemura, Yuzo Ninomiya
Bitter taste serves as an important signal for potentially poisonous compounds in foods to avoid their ingestion. Thousands of compounds are estimated to taste bitter and presumed to activate taste receptor cells expressing bitter taste receptors (Tas2rs) and coupled transduction components including gustducin, phospholipase Cβ2 (PLCβ2) and transient receptor potential channel M5 (TRPM5). Indeed, some gustducin-positive taste cells have been shown to respond to bitter compounds. However, there has been no systematic characterization of their response properties to multiple bitter compounds and the role of transduction molecules in these cells...
November 4, 2017: Neuroscience
https://www.readbyqxmd.com/read/29112285/alcohol-induced-impairment-of-balance-is-antagonized-by-energy-drinks
#18
Cecile A Marczinski, Mark T Fillmore, Amy L Stamates, Sarah F Maloney
BACKGROUND: The acute administration of alcohol reliably impairs balance and motor coordination. While it is common for consumers to ingest alcohol with other stimulant drugs (e.g., caffeine, nicotine), little is known whether prototypical alcohol-induced balance impairments are altered by stimulant drugs. The purpose of this study was to examine whether the coadministration of a high-caffeine energy drink with alcohol can antagonize expected alcohol-induced increases in body sway. METHODS: Sixteen social drinkers (of equal gender) participated in 4 separate double-blind dose administration sessions that involved consumption of alcohol and energy drinks, alone and in combination...
November 7, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29109686/ketone-diester-ingestion-impairs-time-trial-performance-in-professional-cyclists
#19
Jill J Leckey, Megan L Ross, Marc Quod, John A Hawley, Louise M Burke
We investigated the effect of pre- "race" ingestion of a 1,3-butanediol acetoacetate diester on blood ketone concentration, substrate metabolism and performance of a cycling time trial (TT) in professional cyclists. In a randomized cross-over design, 10 elite male cyclists completed a ~31 km laboratory-based TT on a cycling ergometer programmed to simulate the 2017 World Road Cycling Championships course. Cyclists consumed a standardized meal [2 g/kg body mass (BM) carbohydrate (CHO)] the evening prior to a trial day and a CHO breakfast (2 g/kg BM CHO) with 200 mg caffeine on the morning of a trial day...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29091470/acute-ingestion-of-caffeinated-chewing-gum-improves-repeated-sprint-performance-of-team-sports-athletes-with-low-habitual-caffeine-consumption
#20
Mark Evans, Peter Tierney, Nicola Gray, Greg Hawe, Maria Macken, Brendan Egan
The effects of acute ingestion of caffeine on short-duration high intensity performance are equivocal, while studies of novel modes of delivery and the efficacy of low doses of caffeine are warranted. The aims of the present study were to investigate the effect of acute ingestion of caffeinated chewing gum on repeated sprint performance (RSP) in team sport athletes, and whether habitual caffeine consumption alters the ergogenic effect, if any, on RSP. Eighteen male team sports athletes undertook four RSP trials using a 40 m maximum shuttle run test (MST), which incorporates 10x40 m sprints with 30 s between the start of each sprint...
November 1, 2017: International Journal of Sport Nutrition and Exercise Metabolism
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