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Caffeine ingestion

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https://www.readbyqxmd.com/read/29140142/coffee-ingestion-enhances-one-mile-running-race-performance
#1
Neil D Clarke, Darren L Richardson, James Thie, Richard Taylor
PURPOSE: Caffeine, often in the form of coffee, is frequently supplemented by athletes in an attempt to facilitate improved performance during exercise. The aim of the present study was to investigate the effectiveness of coffee ingestion as an ergogenic aid prior to a one-mile (1609 m) race. METHODS: In a double-blind, randomised, crossover, placebo-controlled design 13 trained male runners completed a one-mile race 60 minutes following the ingestion of 0.09 g·kg(-1) coffee (COF), 0...
November 15, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29134560/neurochemical-and-neurotoxic-effects-of-mdma-ecstasy-and-caffeine-after-chronic-combined-administration-in-mice
#2
Anna Maria Górska, Katarzyna Kamińska, Agnieszka Wawrzczak-Bargieła, Giulia Costa, Micaela Morelli, Ryszard Przewłocki, Grzegorz Kreiner, Krystyna Gołembiowska
MDMA (3,4-methylenedioxymethamphetamine) is a psychostimulant popular as a recreational drug because of its effect on mood and social interactions. MDMA acts at dopamine (DA) transporter (DAT) and serotonin (5-HT) transporter (SERT) and is known to induce damage of dopamine and serotonin neurons. MDMA is often ingested with caffeine. Caffeine as a non-selective adenosine A1/A2A receptor antagonist affects dopaminergic and serotonergic transmissions. The aim of the present study was to determine the changes in DA and 5-HT release in the mouse striatum induced by MDMA and caffeine after their chronic administration...
November 13, 2017: Neurotoxicity Research
https://www.readbyqxmd.com/read/29124988/extracorporeal-elimination-of-butalbital-in-acute-aspirin-butalbital-caffeine-codeine-fiorinal-with-codeine-poisoning
#3
Janelle O Poyant, Robert Albright, Jeremy Clain, Govind Pandompatam, Erin F Barreto
BACKGROUND: Butalbital is a small molecule (approximately 220 Da), with 26% protein binding, a 0.8 L/kg volume of distribution, and is eliminated nearly 80% unchanged in the urine. Although hemodialysis has been used to treat overdoses of other barbiturates, the extracorporeal clearance of butalbital is unknown. The objective of this case is to describe the use of extracorporeal therapy to augment elimination of butalbital after an overdose of aspirin 325 mg-butalbital 50 mg-caffeine 40 mg with codeine 30 mg (Fiorinal with Codeine)...
November 10, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/29122414/the-effect-of-hydration-on-voice-quality-in-adults-a-systematic-review
#4
REVIEW
Maxine Alves, Esedra Krüger, Bhavani Pillay, Kristiane van Lierde, Jeannie van der Linde
OBJECTIVES: We aimed to critically appraise scientific, peer-reviewed articles, published in the past 10 years on the effects of hydration on voice quality in adults. STUDY DESIGN: This is a systematic review. METHODS: Five databases were searched using the key words "vocal fold hydration", "voice quality", "vocal fold dehydration", and "hygienic voice therapy". The Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines were followed...
November 6, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29113930/bitter-taste-responses-of-gustducin-positive-taste-cells-in-mouse-fungiform-and-circumvallate-papillae
#5
Ryusuke Yoshida, Shingo Takai, Keisuke Sanematsu, Robert F Margolskee, Noriatsu Shigemura, Yuzo Ninomiya
Bitter taste serves as an important signal for potentially poisonous compounds in foods to avoid their ingestion. Thousands of compounds are estimated to taste bitter and presumed to activate taste receptor cells expressing bitter taste receptors (Tas2rs) and coupled transduction components including gustducin, phospholipase Cβ2 (PLCβ2) and transient receptor potential channel M5 (TRPM5). Indeed, some gustducin-positive taste cells have been shown to respond to bitter compounds. However, there has been no systematic characterization of their response properties to multiple bitter compounds and the role of transduction molecules in these cells...
November 4, 2017: Neuroscience
https://www.readbyqxmd.com/read/29112285/alcohol-induced-impairment-of-balance-is-antagonized-by-energy-drinks
#6
Cecile A Marczinski, Mark T Fillmore, Amy L Stamates, Sarah F Maloney
BACKGROUND: The acute administration of alcohol reliably impairs balance and motor coordination. While it is common for consumers to ingest alcohol with other stimulant drugs (e.g., caffeine, nicotine), little is known whether prototypical alcohol-induced balance impairments are altered by stimulant drugs. The purpose of this study was to examine whether the coadministration of a high-caffeine energy drink with alcohol can antagonize expected alcohol-induced increases in body sway. METHODS: Sixteen social drinkers (of equal gender) participated in 4 separate double-blind dose administration sessions that involved consumption of alcohol and energy drinks, alone and in combination...
November 7, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29109686/ketone-diester-ingestion-impairs-time-trial-performance-in-professional-cyclists
#7
Jill J Leckey, Megan L Ross, Marc Quod, John A Hawley, Louise M Burke
We investigated the effect of pre- "race" ingestion of a 1,3-butanediol acetoacetate diester on blood ketone concentration, substrate metabolism and performance of a cycling time trial (TT) in professional cyclists. In a randomized cross-over design, 10 elite male cyclists completed a ~31 km laboratory-based TT on a cycling ergometer programmed to simulate the 2017 World Road Cycling Championships course. Cyclists consumed a standardized meal [2 g/kg body mass (BM) carbohydrate (CHO)] the evening prior to a trial day and a CHO breakfast (2 g/kg BM CHO) with 200 mg caffeine on the morning of a trial day...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29091470/acute-ingestion-of-caffeinated-chewing-gum-improves-repeated-sprint-performance-of-team-sports-athletes-with-low-habitual-caffeine-consumption
#8
Mark Evans, Peter Tierney, Nicola Gray, Greg Hawe, Maria Macken, Brendan Egan
The effects of acute ingestion of caffeine on short-duration high intensity performance are equivocal, while studies of novel modes of delivery and the efficacy of low doses of caffeine are warranted. The aims of the present study were to investigate the effect of acute ingestion of caffeinated chewing gum on repeated sprint performance (RSP) in team sport athletes, and whether habitual caffeine consumption alters the ergogenic effect, if any, on RSP. Eighteen male team sports athletes undertook four RSP trials using a 40 m maximum shuttle run test (MST), which incorporates 10x40 m sprints with 30 s between the start of each sprint...
November 1, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29091469/case-study-dose-response-of-caffeine-on-20-km-handcycling-time-trial-performance-in-a-para-triathlete
#9
Terri Graham-Paulson, Claudio Perret, Victoria Goosey-Tolfrey
Caffeine's ability to influence upper-body exercise (UBE) endurance performance may be related to an individual's training status. This case study therefore aimed to investigate the ergogenic effects of caffeine dose on 20 km time trial (TT) performance of an elite male Para-triathlete (wheelchair user) (age 46 y, body mass 76.9 kg, body fat 25.4%, handcycling V̇O2peak 3.45 l·min(-1)). The athlete completed four 20 km handcycling TT's on a Cyclus II ergometer under laboratory controlled conditions following the ingestion of 2, 4 and 6 mg·kg(-1) caffeine (CAF) or placebo (PLA)...
November 1, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29081083/ionotropic-receptor-76b-is-required-for-gustatory-aversion-to-excessive-na-in-drosophila
#10
Min Jung Lee, Ha Yeon Sung, HyunJi Jo, Hyung-Wook Kim, Min Sung Choi, Jae Young Kwon, KyeongJin Kang
Avoiding ingestion of excessively salty food is essential for cation homeostasis that underlies various physiological processes in organisms. The molecular and cellular basis of the aversive salt taste, however, remains elusive. Through a behavioral reverse genetic screening, we discover that feeding suppression by Na(+)-rich food requires Ionotropic Receptor 76b (Ir76b) in Drosophila labellar gustatory receptor neurons (GRNs). Concentrated sodium solutions with various anions caused feeding suppression dependent on Ir76b...
October 2017: Molecules and Cells
https://www.readbyqxmd.com/read/29065052/energy-drink-doses-of-caffeine-and-taurine-have-a-null-or-negative-effect-on-sprint-performance
#11
Owen Jeffries, Jessica Hill, Stephen D Patterson, Mark Waldron
This study investigated the effects of caffeine and taurine co-ingestion on repeat-sprint cycling performance and associated physiological and perceptual responses. In a double blind, cross-over, repeated measures study, 11 male participants (age 21 ± 2 years; stature 178 ± 7 cm; body mass 80 ± 13 kg) completed 10 x 6-s sprints on a cycle ergometer, each separated by 24-s, an hour after ingesting: caffeine (80 mg) and taurine (1 g), equivalent to the amount observed in popular commercial energy drinks, or placebo (maltodextrin ∼1 g) in a gelatine capsule...
October 23, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29055810/prenatal-caffeine-ingestion-increases-susceptibility-to-pulmonary-inflammation-in-adult-female-rat-offspring
#12
Han-Xiao Liu, Li-Fang Hou, Ting Chen, Wen Qu, Sha Liu, Hui-Yi Yan, Xiao Wen, Jie Ping
This study aimed to investigate the association between prenatal caffeine ingestion (PCI) and risk of postnatal pulmonary inflammation. Pregnant Wistar rats were administered 60mg/kg/d caffeine intragastrically from gestational day (GD) 7 to GD 20. The results showed that PCI obviously increased intrauterine growth retardation rate to 39.2% and suppressed weight growth of the offspring. PCI also enhanced the expression of transforming growth factor β, α-smooth muscle actin, interleukin (IL)-1β, and IL-8 in lungs and caused pulmonary interstitial thickening in the offspring...
October 18, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/29035597/influence-of-2-weeks-ingestion-of-high-chlorogenic-acid-coffee-on-mood-state-performance-and-post-exercise-inflammation-and-oxidative-stress-a-randomized-placebo-controlled-trial
#13
David C Nieman, Courtney L Goodman, Christopher R Capps, Zack L Shue, Robert Arnot
This study measured the influence of 2-weeks ingestion of high chlorogenic acid (CQA) coffee on post-exercise inflammation and oxidative stress, with secondary outcomes including performance and mood state. Cyclists (N=15) were randomized to CQA coffee or placebo (300 ml/day) for 2 weeks, participated in a 50-km cycling time trial, and then crossed over to the opposite condition with a 2-week washout period. Blood samples were collected pre- and post-supplementation, and immediately post-exercise. CQA coffee was prepared using the Turkish method with 30 g lightly roasted, highly ground Hambela coffee beans in 300 ml boiling water, and provided 1,066 mg CQA and 474 mg caffeine versus 187 mg CQA and 33 mg caffeine for placebo...
October 16, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29029291/nutrition-influences-caffeine-mediated-sleep-loss-in-drosophila
#14
Erin S Keebaugh, Jin Hong Park, Chenchen Su, Ryuichi Yamada, William W Ja
Study objectives: Plant-derived caffeine is regarded as a defensive compound produced to prevent herbivory. Caffeine is generally repellent to insects and often used to study the neurological basis for aversive responses in the model insect, Drosophila melanogaster. Caffeine is also studied for its stimulatory properties where sleep or drowsiness is suppressed across a range of species. Since limiting access to food also inhibits fly sleep-an effect known as starvation-induced sleep suppression-we tested whether aversion to caffeinated food results in reduced nutrient intake and assessed how this might influence fly studies on the stimulatory effects of caffeine...
October 3, 2017: Sleep
https://www.readbyqxmd.com/read/28991045/caffeine-ingestion-attenuates-fatigue-induced-loss-of-muscle-torque-complexity
#15
Jamie Pethick, Samantha L Winter, Mark Burnley
The temporal structure, or complexity, of muscle torque output decreases with neuromuscular fatigue. The role of central fatigue in this process is unclear. PURPOSE: We tested the hypothesis that caffeine administration would attenuate the fatigue-induced loss of torque complexity. METHODS: Eleven healthy participants performed intermittent isometric contractions of the knee extensors to task failure at a target torque of 50% maximal voluntary contraction (MVC), with a 60% duty factor (6 s contraction, 4 s rest), 60 min after ingesting 6 mg·kg caffeine or a placebo...
October 3, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28945675/the-effect-of-acute-taurine-ingestion-on-human-maximal-voluntary-muscle-contraction
#16
Zi Xiang Lim, Anish Singh, Zac Zi Xiang Leow, Peter G Arthur, Paul A Fournier
PURPOSE: To examine the effect of taurine ingestion on maximal voluntary muscle torque and power in trained male athletes with different caffeine habits. METHODS: Fourteen male athletes aged 21.8 ± 2.5 years were separated into caffeine and non-caffeine consumers to control for the effect of caffeine withdrawal on muscle function. On separate occasions, participants performed four isokinetic or three maximal isometric knee extensions with and without taurine (40 mg/kg body mass) following a double blind, counterbalanced design...
September 22, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28942033/nature-versus-intensity-of-intoxication-co-ingestion-of-alcohol-and-energy-drinks-and-the-effect-on-objective-and-subjective-intoxication
#17
Jessica Forward, Jane Akhurst, Raimondo Bruno, Xiao Leong, Amelia VanderNiet, Holly Bromfield, Jacqueline Erny, Tessa Bellamy, Amy Peacock
BACKGROUND: We report a series of studies examining the effect of alcohol mixed with energy drinks (AmEDs) versus alcohol on objective intoxication (breath alcohol concentration; BrAC), intensity, and nature of intoxication. We also aimed to disentangle the role of energy drink (ED) ingredients in any effects. METHOD: Three within-subject double-blind placebo-controlled studies measured BrAC, subjective intoxication and impairment ('intensity of intoxication'), stimulation and sedation ('nature of intoxication') following administration of ED, Cola, Caffeine+Sugar, and Placebo with alcohol (Study 1, n=18); ED, Caffeine-only, Sugar-only and Placebo with alcohol (Study 2, n=20); and ED and Placebo with alcohol (Study 3, n=27)...
September 7, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28925969/caffeine-improves-basketball-performance-in-experienced-basketball-players
#18
Carlos Puente, Javier Abián-Vicén, Juan José Salinero, Beatriz Lara, Francisco Areces, Juan Del Coso
The aim of this study was to determine the effect of caffeine intake on overall basketball performance in experienced players. A double-blind, placebo-controlled, randomized experimental design was used for this investigation. In two different sessions separated by one week, 20 experienced basketball players ingested 3 mg of caffeine/kg of body mass or a placebo. After 60 min, participants performed 10 repetitions of the following sequence: Abalakov jump, Change-of-Direction and Acceleration Test (CODAT) and two free throws...
September 19, 2017: Nutrients
https://www.readbyqxmd.com/read/28919842/international-society-of-sports-nutrition-position-stand-nutrient-timing
#19
REVIEW
Chad M Kerksick, Shawn Arent, Brad J Schoenfeld, Jeffrey R Stout, Bill Campbell, Colin D Wilborn, Lem Taylor, Doug Kalman, Abbie E Smith-Ryan, Richard B Kreider, Darryn Willoughby, Paul J Arciero, Trisha A VanDusseldorp, Michael J Ormsbee, Robert Wildman, Mike Greenwood, Tim N Ziegenfuss, Alan A Aragon, Jose Antonio
The International Society of Sports Nutrition (ISSN) provides an objective and critical review regarding the timing of macronutrients in reference to healthy, exercising adults and in particular highly trained individuals on exercise performance and body composition. The following points summarize the position of the ISSN:Nutrient timing incorporates the use of methodical planning and eating of whole foods, fortified foods and dietary supplements. The timing of energy intake and the ratio of certain ingested macronutrients may enhance recovery and tissue repair, augment muscle protein synthesis (MPS), and improve mood states following high-volume or intense exercise...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/28913843/food-and-functional-dyspepsia-a-systematic-review
#20
REVIEW
K R Duncanson, N J Talley, M M Walker, T L Burrows
BACKGROUND: Functional dyspepsia (FD) is a debilitating functional gastrointestinal disorder characterised by early satiety, post-prandial fullness or epigastric pain related to meals, which affects up to 20% of western populations. A high dietary fat intake has been linked to FD and duodenal eosinophilia has been noted in FD. We hypothesised that an allergen such as wheat is a risk factor for FD and that withdrawal will improve symptoms of FD. We aimed to investigate the relationship between food and functional dyspepsia...
September 15, 2017: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
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