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Caffeine ingestion

João Paulo Lopes-Silva, Jonatas Ferreira da Silva Santos, Braulio Henrique Magnani Branco, César Cavinato Cal Abad, Luana Farias de Oliveira, Irineu Loturco, Emerson Franchini
[This corrects the article DOI: 10.1371/journal.pone.0142078.].
2016: PloS One
Ross Beaumont, Philip Cordery, Mark Funnell, Stephen Mears, Lewis James, Phillip Watson
This study examined effects of 4 weeks of caffeine supplementation on endurance performance. Eighteen low-habitual caffeine consumers (<75 mg · day(-1)) were randomly assigned to ingest caffeine (1.5-3.0 mg · kg(-1)day(-1); titrated) or placebo for 28 days. Groups were matched for age, body mass, V̇O2peak and Wmax (P > 0.05). Before supplementation, all participants completed one V̇O2peak test, one practice trial and 2 experimental trials (acute 3 mg · kg(-1) caffeine [precaf] and placebo [testpla])...
October 20, 2016: Journal of Sports Sciences
Diego B Souza, Juan Del Coso, Juliano Casonatto, Marcos D Polito
PURPOSE: Caffeine-containing energy drinks (EDs) are currently used as ergogenic aids to improve physical performance in a wide variety of sport disciplines. However, the outcomes of previous investigations on this topic are inconclusive due to methodological differences, especially, in the dosage of the active ingredients and the test used to assess performance. METHODS: We performed a systematic review and meta-analysis of published studies to evaluate the effects of acute ED intake on physical performance...
October 18, 2016: European Journal of Nutrition
Priccila Zuchinali, Gabriela C Souza, Maurício Pimentel, Diego Chemello, André Zimerman, Vanessa Giaretta, Joyce Salamoni, Bianca Fracasso, Leandro I Zimerman, Luis E Rohde
Importance: The presumed proarrhythmic action of caffeine is controversial. Few studies have assessed the effect of high doses of caffeine in patients with heart failure due to left ventricular systolic dysfunction at high risk for ventricular arrhythmias. Objective: To compare the effect of high-dose caffeine or placebo on the frequency of supraventricular and ventricular arrhythmias, both at rest and during a symptom-limited exercise test. Design, Setting, and Participants: Double-blinded randomized clinical trial with a crossover design conducted at the heart failure and cardiac transplant clinic of a tertiary-care university hospital...
October 17, 2016: JAMA Internal Medicine
Zoya Zaeem, Lily Zhou, Esma Dilli
Dietary triggers are commonly reported by patients with a variety of headaches, particularly those with migraines. The presence of any specific dietary trigger in migraine patients varies from 10 to 64 % depending on study population and methodology. Some foods trigger headache within an hour while others develop within 12 h post ingestion. Alcohol (especially red wine and beer), chocolate, caffeine, dairy products such as aged cheese, food preservatives with nitrates and nitrites, monosodium glutamate (MSG), and artificial sweeteners such as aspartame have all been studied as migraine triggers in the past...
November 2016: Current Neurology and Neuroscience Reports
James M Green, Alyssa Olenick, Caroline Eastep, Lee Winchester
Caffeine (CAF) blunts estimated ratings of perceived exertion (RPE) but the effects on RPE production are unclear. This study examined effects of acute caffeine ingestion during treadmill exercise where participants exercised at prescribed RPE 4 and 7. Recreational runners (maximal oxygen consumption = 51.4 ± 9.8 mL·kg(-1)·min(-1)) (n = 16) completed a maximal treadmill test followed by trials where they selected treadmill velocity (VEL) (1% grade) to produce RPE 4 and RPE 7 (10 min each). RPE production trials followed CAF (6 mg·kg(-1)) or placebo (PLA) (counterbalanced) ingestion...
June 30, 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
Rafael Azevedo, Marcos David Silva-Cavalcante, Bruno Gualano, Adriano E Lima-Silva, Romulo Bertuzzi
PURPOSE: To examine the effects of caffeine ingestion on physiological and perceptual responses in mentally fatigued individuals. METHODS: Eight male physically active subjects completed four cycling constant-workload tests in four experimental conditions at 80 % of maximal power output: control (C), mental fatigue (MF), mental fatigue plus caffeine ingestion (5 mg/kg) (MF-CAF), and mental fatigue plus placebo (MF-PLA). The mental fatigue was induced by a continuous performance task A-X version (AX-CPT)...
September 30, 2016: European Journal of Applied Physiology
Maseeh Uz Zaman, Nosheen Fatima, Areeba Zaman, Unaiza Zaman, Rabia Tahseen
For vasodilator stress, myocardial perfusion imaging (MPI) with at least 12-h caffeine abstinence is recommended, as it attenuates cardiovascular hyperemic response of adenosine and dipyridamole. However, many published conflicting results have shown no significant effect upon perfusion abnormalities in MPI performed without caffeine abstinence. The aim of this study was to compare the hemodynamic changes and negative predictive value (NPV) of normal MPIs with adenosine stress performed with or without caffeine abstinence...
September 2016: World Journal of Nuclear Medicine
Erik Konrad Grasser, Jennifer Lynn Miles-Chan, Nathalie Charrière, Cathríona R Loonam, Abdul G Dulloo, Jean-Pierre Montani
Globally, the popularity of energy drinks is steadily increasing. Scientific interest in their effects on cardiovascular and cerebrovascular systems in humans is also expanding and with it comes a growing number of case reports of adverse events associated with energy drinks. The vast majority of studies carried out in the general population report effects on blood pressure and heart rate. However, inconsistencies in the current literature render it difficult to draw firm conclusions with regard to the effects of energy drinks on cardiovascular and cerebrovascular variables...
September 2016: Advances in Nutrition
Joseph G Lisko, Grace E Lee, J Brett Kimbrell, Michael E Rybak, Liza Valentin-Blasini, Clifford H Watson
INTRODUCTION: Most electronic cigarettes (e-cigarettes) contain a solution of propylene glycol/glycerin and nicotine, as well as flavors. E-cigarettes and their associated e-liquids are available in numerous flavor varieties. A subset of the flavor varieties include coffee, tea, chocolate, and energy drink, which, in beverage form, are commonly recognized sources of caffeine. Recently, some manufacturers have begun marketing e-liquid products as energy enhancers that contain caffeine as an additive...
July 25, 2016: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
Meridith T Robins, Julia N DeFriel, Richard M van Rijn
The rise in marketing and mass consumption of energy drink products by adolescents poses a largely unknown risk on adolescent development and drug reward. Yet, with increasing reports of acute health issues present in young adults who ingest large quantities of energy drinks alone or in combination with alcohol, the need to elucidate these potential risks is pressing. Energy drinks contain high levels of caffeine and sucrose; therefore, exposure to energy drinks may lead to changes in drug-related behaviors since caffeine and sucrose consumption activates similar brain pathways engaged by substances of abuse...
August 2016: Alcohol
Aaron R Caldwell, Matthew A Tucker, Cory L Butts, Brendon P McDermott, Jakob L Vingren, Laura J Kunces, Elaine C Lee, Colleen X Munoz, Keith Williamson, Lawrence E Armstrong, Matthew S Ganio
Caffeine can reduce muscle pain during exercise; however the efficacy of caffeine in improving muscle soreness and recovery from a demanding long-duration exercise bout has not been established. The purpose of this study was to investigate the effects of caffeine intake on ratings of perceived muscle soreness (RPMS) and perceived lower extremity functionality (LEF) following the completion of a 164-km endurance cycling event. Prior to and after cycling RPMS (1-to-6; 6=severe soreness) and LEF (0-to-80; 80=full functionality) were assessed via questionnaires...
August 19, 2016: Journal of Strength and Conditioning Research
Mark Glaister, Benjamin Henley Williams, Daniel Muniz-Pumares, Carlos Balsalobre-Fernández, Paul Foley
OBJECTIVES: The aim of this study was to evaluate the effects of caffeine on physiological responses to submaximal exercise, with a focus on blood lactate concentration ([BLa]). METHODS: Using a randomised, single-blind, crossover design; 16 endurance-trained, male cyclists (age: 38 ± 8 years; height: 1.80 ± 0.05 m; body mass: 76.6 ± 7.8 kg; [Formula: see text]: 4.3 ± 0.6 L∙min-1) completed four trials on an electromagnetically-braked cycle ergometer. Each trial consisted of a six-stage incremental test (3 minute stages) followed by 30 minutes of passive recovery...
2016: PloS One
Jaekyun Choi, Lena van Giesen, Min Sung Choi, KyeongJin Kang, Simon G Sprecher, Jae Young Kwon
The sense of taste is an essential chemosensory modality that enables animals to identify appropriate food sources and control feeding behavior. In particular, the recognition of bitter taste prevents animals from feeding on harmful substances. Feeding is a complex behavior comprised of multiple steps, and food quality is continuously assessed. We here examined the role of pharyngeal gustatory organs in ingestion behavior. As a first step, we constructed a gustatory receptor-to-neuron map of the larval pharyngeal sense organs, and examined corresponding gustatory receptor neuron (GRN) projections in the larval brain...
2016: Frontiers in Cellular Neuroscience
Nic Martinez, Bill Campbell, Madison Franek, Laura Buchanan, Ryan Colquhoun
BACKGROUND: Consumption of pre-workout dietary supplements by both recreational and competitive athletes has increased dramatically in recent years. The purpose of this study was to determine the acute effects of a caffeine-containing pre-workout dietary supplement on various measures of performance including anaerobic power, upper and lower body power, and upper body strength in recreationally trained males. METHODS: Thirteen males (mean ± SD age = 24 ± 6 yrs; height = 180...
2016: Journal of the International Society of Sports Nutrition
Jason L Talanian, Lawrence L Spriet
The aim of the present study was to assess if low and moderate doses of caffeine delivered in a carbohydrate-electrolyte solution (CES) late in exercise improved time-trial (TT) performance. Fifteen (11 male, 4 female) cyclists (age, 22.5 ± 0.9 years; body mass, 69.3 ± 2.6 kg; peak oxygen consumption, 64.6 ± 1.9 mL·min(-1)·kg(-1)) completed 4 double-blinded randomized trials. Subjects completed 120 min of cycling at ∼60% peak oxygen consumption with 5 interspersed 120-s intervals at ∼82% peak oxygen consumption, immediately followed by 40-s intervals at 50 W...
August 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
Willard W Peveler, Gabe Sanders, Cecile Marczinski, Brady Holmer
The use of energy drinks among athletes has risen greatly. Caffeine and taurine are the two primary performance enhancing ingredients found in energy drinks. The number of emergency department visits involving energy drinks doubled over the last 5 years. Reviews of the health complications have highlighted adverse cardiovascular events. The literature reveals that caffeine is known to moderately increase blood pressure and heart rate. The purpose of this study was to determine the effect of three different energy drinks on cardiovascular and performance measures...
July 5, 2016: Journal of Strength and Conditioning Research
Ching-Feng Cheng, Wei-Chieh Hsu, Yu-Hsuan Kuo, Ming-Tsung Shih, Chia-Lun Lee
PURPOSE: To investigate the effect of caffeine ingestion on the 3-min all-out test (3MT) performance and plasma electrolytes in athletes. METHODS: Fifteen collegiate male basketball players were recruited and completed two trials separated by at least 1 week in caffeine (CAF, 6 mg kg(-1)) and placebo conditions. During the first visit, participants performed an incremental cycling test to determine their 3MT resistance. After a familiarization trial, participants performed a CAF or PL trial according to a randomized crossover design...
September 2016: European Journal of Applied Physiology
Terri Graham-Paulson, Claudio Perret, Victoria Goosey-Tolfrey
Caffeine supplementation during whole-/lower-body exercise is well-researched, yet evidence of its effect during upper-body exercise is equivocal. The current study explored the effects of caffeine on cycling/handcycling 10 km time trial (TT) performance in habitual caffeine users. Eleven recreationally trained males (mean (SD) age 24 (4) years, body mass 85.1 (14.6) kg, cycling/handcycling peak oxygen uptake ( V · peak) 42.9 (7.3)/27.6 (5.1) mL∙kg∙min(-1), 160 (168) mg/day caffeine consumption) completed two maximal incremental tests and two familiarization sessions...
2016: Nutrients
Luisa Muraro, Laura Longo, Federico Geraldini, Andrea Bortot, Andrea Paoli, Annalisa Boscolo
Caffeine is arguably the most widely used stimulant drug in the world. Here we describe a suicide attempt involving caffeine overdose whereby the patient's severe intoxication was successfully treated with the prompt infusion of Intralipid. A 19-year-old man was found in an agitated state at home by the volunteer emergency team about 1 h after the intentional ingestion of 40 g of caffeine (tablets). His consciousness decreased rapidly, followed quickly by seizures, and electrocardiographic monitoring showed ventricular fibrillation...
October 2016: Journal of Anesthesia
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