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https://www.readbyqxmd.com/read/29054124/historical-demography-and-colonisation-pathways-of-the-widespread-intertidal-seaweed-hormosira-banksii-phaeophyceae-in-southeastern-australia
#1
Rebecca Mueller, Jeffrey T Wright, Christopher J S Bolch
The palaeoceanography of southern Australia has been characterized by fluctuating sea levels during glacial periods, changing temperature regimes and modified boundary currents. Previous studies on genetic structuring of species in southeastern Australia have focused mainly on the differentiation of eastern and western populations while the potential role of Bass Strait as a region of overlap for three biogeographic provinces (Peronia, Maugea, and Flindersia) has been largely ignored. This study aimed to explore the likely roles of historic and contemporary factors in determining divergence patterns in the habitat-forming intertidal seaweed Hormosira banksii in southeastern Australia with a special focus on postglacial dispersal into Bass Strait...
October 20, 2017: Journal of Phycology
https://www.readbyqxmd.com/read/29054121/multisensory-modulation-of-experimentally-evoked-perceptual-distortion-of-the-face
#2
Lilja K Dagsdóttir, Valeria Bellan, Ina Skyt, Lene Vase, Lene Baad-Hansen, Eduardo Castrillon, Peter Svensson
Chronic orofacial pain patients often perceive the painful face area as 'swollen' without clinical signs, i.e., a perceptual distortion (PD). Local anesthetic (LA) injections in healthy participants are also associated with PD OBJECTIVE: The aim was to explore whether PD evoked by LA into the infraorbital region of could be modulated by adding mechanical stimulation (MS) to the affected area METHODS: MS was given with a brush and a 128 mN von Frey filament. First, sixty healthy participants were randomly divided into three groups: 1) LA control, 2) LA with MS, 3) Isotonic solution (ISO) with MS as an additional control condition...
October 20, 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/29054118/efficacy-of-laryngectomy-alone-for-treatment-of-locally-advanced-laryngeal-cancer-a-stage-and-subsite-specific-survival-analysis
#3
Brian P Cervenka, Shyam Rao, D Gregory Farwell, Arnaud F Bewley
OBJECTIVE: Total laryngectomy is a well-established treatment for locally advanced laryngeal cancer. Evidence for the benefit of post-operative radiotherapy after laryngectomy in patients with locally advanced primaries and N0 or N1 nodal disease is limited. This study aims to determine whether total laryngectomy alone is adequate therapy for certain patient subgroups with locally advanced laryngeal cancer. DESIGN: We performed a retrospective survival analysis of patients in the surveillance epidemiology and end results (SEER) database with locally advanced laryngeal cancer between 2004-2012...
October 20, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29054111/dipeptidyl-peptidase-4-inhibitors-attenuates-the-decline-of-skeletal-muscle-mass-in-patients-with-type-2-diabetes
#4
Ryotaro Bouchi, Tatsuya Fukuda, Takato Takeuchi, Yujiro Nakano, Masanori Murakami, Isao Minami, Hajime Izumiyama, Koshi Hashimoto, Takanobu Yoshimoto, Yoshihiro Ogawa
BACKGROUND: Activation of dipeptidyl peptidase 4 (DPP4) has been reported to be associated with impairment of insulin signaling in skeletal muscle mass, presumably leading to loss of muscle function. This study was aimed to investigate whether the use of DPP4 inhibitors (DPP4i) could attenuate the progressive loss of muscle mass in patients with type 2 diabetes. METHODS: A total 105 patients with type 2 diabetes (mean age 62 ± 12 years; 39% female) were studied in this retrospective observational study...
October 20, 2017: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/29054099/examining-factors-associated-with-elevated-lie-scale-responding-on-the-child-abuse-potential-inventory
#5
Amanda H Costello, Natalie J Shook, Nancy M Wallace, Cheryl B McNeil
Child maltreatment remains a serious public health issue in the United States. Therefore, it is important to engage in quality control of the assessment, prevention, and treatment services for families affected by maltreatment. Parenting capacity assessments (PCAs) are typically an integral part of service delivery for families affected by maltreatment and can carry serious consequences for the referred parent. The Child Abuse Potential Inventory (CAPI) is a measure that is widely used in PCAs; however, socially desirable responding on the CAPI can serve to invalidate the important information derived from this assessment, as well as lead to negative impressions of the parent...
October 17, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29054093/the-role-of-pazopanib-on-tumour-angiogenesis-and-in-the-management-of-cancers-a-review
#6
REVIEW
Dinesh Kumar Chellappan, Jestin Chellian, Zhao Yin Ng, Yan Jinn Sim, Chiu Wei Theng, Joyce Ling, Mei Wong, Jia Hui Foo, Goh Jun Yang, Li Yu Hang, Saranyah Nathan, Yogendra Singh, Gaurav Gupta
Pazopanib is a relatively new compound to be introduced into the chemotherapy field. It is thought to have decent anti-angiogenic properties, which gives an additional hope for the treatment of certain types of cancers. A systematic review solely discussing about pazopanib and its anti-angiogenic effect is yet to be published to date, despite several relevant clinical trials being conducted over the recent years. In this review, we aim to investigate the mechanism of pazopanib's anti-angiogenic effect and its effectiveness in treating several cancers...
October 17, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29054092/protein-mimicking-nanoparticles-for-the-reproduction-of-transient-protein-receptor-interactions
#7
Jonghwan Lee
One of the major concerns in target identification has been the need for new methods to detect target molecules in the native cellular environment. In conventional target identification, affinity-based pull down has been conducted using cell lysates. However, interactions in cell lysate do not reflect real endogenous interactions in living cells, and can produce false-positive or false-negative results. This study aimed to develop a new method of target protein identification in living cells. Targeting probes were conjugated onto magnetic nanoparticles (MNPs)...
October 7, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29054091/early-adolescents-body-dysmorphic-symptoms-as-compensatory-responses-to-parental-appearance-messages-and-appearance-based-rejection-sensitivity
#8
Kelly Densham, Haley J Webb, Melanie J Zimmer-Gembeck, Drew Nesdale, Geraldine Downey
Body dysmorphic disorder (BDD) is marked by high distress and behavioral and functional impairments due to preoccupation with perceived appearance anomalies. Our aim was to examine parental correlates of offspring's symptoms characteristic of BDD, testing both direct associations and indirect associations via appearance-based rejection sensitivity (appearance-RS). Surveys were completed by 302 Australian adolescents (9-14 years) and their parents. Findings indicated parents' weight and appearance teasing and child-report (but not parent-report) of parental negative attitudes about weight and appearance were uniquely associated with offspring's heightened BDD-like symptoms, and associations were partially indirect via adolescents' appearance-RS...
October 17, 2017: Body Image
https://www.readbyqxmd.com/read/29054088/the-interactions-among-organophosphate-pesticide-exposure-oxidative-stress-and-genetic-polymorphisms-of-dopamine-receptor-d4-increase-the-risk-of-attention-deficit-hyperactivity-disorder-in-children
#9
Chia-Huang Chang, Ching-Jung Yu, Jung-Chieh Du, Hsien-Chih Chiou, Hsin-Chang Chen, Winnie Yang, Ming-Yi Chung, Ying-Sheue Chen, Betau Hwang, I-Fang Mao, Mei-Lien Chen
OBJECTIVE: The aim of this study was to clarify the association between organophosphate pesticides (OPs) and attention-deficit/hyperactivity disorder (ADHD) related to oxidative stress and genetic polymorphisms. METHODS: This case-control study enrolled 93 children with ADHD and 112 control children in north Taiwan. Six dialkyl phosphate (DAP) metabolites of OPs and oxidative stress biomarkers were analyzed. Polymorphisms of the dopamine receptor D4 gene (DRD4) were identified...
October 17, 2017: Environmental Research
https://www.readbyqxmd.com/read/29054065/investigating-desorption-during-ethanol-elution-to-improve-the-quality-and-antioxidant-activity-of-xylo-oligosaccharides-from-corn-stalk
#10
Jie Zhang, Yue-Hai Wang, Quan-Yuan Wei, Xiao-Jia Du, Yong-Shui Qu
As the most representative of lignocellulosic materials, corn stalk (CS) will be a great candidate to produce xylo-oligosaccharides (XOS). Owing to the high impurity content of the XOS produced by directly enzymatic hydrolysis of xylan extracted from CS, subsequent refining steps are essential. The present study was aimed to investigate desorption during ethanol elution to improve the quality and antioxidant activity of XOS from CS. The desorption was systematically investigated after optimizing the elution conditions...
October 4, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/29054054/conformational-analysis-of-the-human-chemokine-receptor-cxcr3
#11
Raffaele Raucci, Andrea Polo, Alfredo Budillon, Giovanni Colonna, Susan Costantini
In the last years, some studies showed the patho-genetic role of CXCR3 bound to its ligands in many human inflammatory diseases and cancers. Thus, the blockage of the CXCR3 interaction site to its ligands is seen as a possible therapeutic target for the treatment of cancer. The presence of flexible regions in the chemokine receptors determines their capability to develop specific mechanisms of action. We have recently focused on the features of the N-terminal region of human CXCR3 free in solution, where we demonstrate the presence of numerous conformational ensembles, dynamically stabilized by H-bonds...
October 17, 2017: Molecular Immunology
https://www.readbyqxmd.com/read/29054051/the-incidence-and-risk-factors-of-epilepsy-in-children-born-preterm-a-nationwide-register-study
#12
Mikko Hirvonen, Riitta Ojala, Päivi Korhonen, Paula Haataja, Kai Eriksson, Mika Gissler, Tiina Luukkaala, Outi Tammela
OBJECTIVES: The aim was to compare the incidence of epilepsy between very preterm (VP) (<32(+0) weeks), moderately preterm (MP) (32(+0)-33(+6) weeks), late preterm (LP) (34(+0)-36(+6) weeks) and term infants (≥37 weeks) and to establish and compare risk factors of epilepsy in these groups. METHODS: The national register study included all live born infants in Finland in 1991-2008. Excluding infants with missing gestational age, a total of 1,033,349 infants were included in the analysis and they were analyzed in four subgroups (VP, MP, LP and term) and three time periods (1991-1995, 1996-2001 and 2002-2008)...
October 14, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/29054033/hepatitis-c-antibody-prevalence-among-mexico-city-prisoners-injecting-legal-and-illegal-substances
#13
Omar Silverman-Retana, Edson Serván-Mori, Sandra I McCoy, Sarah Larney, Sergio Bautista-Arredondo
BACKGROUND: Hepatitis C virus (HCV) infection is highly prevalent among prisoners and this prevalence estimates reach 64% among prisoners who inject illicit drugs. Prisons are important sites for HCV transmission in the absence of access to sterile injecting equipment; hence, it can be transmitted between prisoners who share contaminated needles and syringes. We aimed to estimate the prevalence of risk factors for anti-HCV prevalence, with particular interest on injecting behavior, and to assess correlates of anti-HCV positivity among Mexico City prisoners...
October 14, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29054028/impact-of-fomesafen-on-the-soil-microbial-communities-in-soybean-fields-in-northeastern-china
#14
Xiao-Hu Wu, Ying Zhang, Peng-Qiang Du, Jun Xu, Feng-Shou Dong, Xin-Gang Liu, Yong-Quan Zheng
Fomesafen, a widely adopted residual herbicide, is used throughout the soybean region of northern China for the spring planting. However, the ecological risks of using fomesafen in soil remain unknown. The aim of this work was to evaluate the impact of fomesafen on the microbial community structure of soil using laboratory and field experiments. Under laboratory conditions, the application of fomesafen at concentrations of 3.75 and 37.5mg/kg decreased the basal respiration (RB) and microbial biomass carbon (MBC)...
October 17, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29054025/antibacterial-activity-against-cariogenic-bacteria-and-cytotoxic-and-genotoxic-potential-of-anacardium-occidentale-l-and-anadenanthera-macrocarpa-benth-brenan-extracts
#15
Josenildo Segundo Chaves de Araújo, Aline Rogéria Freire de Castilho, Andressa Brito Lira, Andréia Vieira Pereira, Tatiane Kelly Barbosa de Azevêdo, Edja Maria de Melo de Brito Costa, Maria do Socorro Vieira Pereira, Hilzeth Freire Luna Pessoa, Jozinete Vieira Pereira
OBJECTIVES: The present study aimed to assess the antibacterial activity against bacteria with cariogenic relevance, toxic and genotoxic potential of the plants Anacardium occidentale L. and Anadenanthera macrocarpa (Benth.) Bernam. DESIGN: Using a microdilution technique, the extracts were submitted to minimum inhibitory concentration (MIC) testing against Streptococcus mitis (ATCC 903), Streptococcus mutans (ATCC 25175), Streptococcus oralis (ATCC 10557), Streptococcus salivarius (ATCC 7073), Streptococcus sanguinis (ATCC 15300) and Streptococcus sobrinus (ATCC 27609)...
October 14, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29054024/social-skills-plus-relaxation-training-with-a-child-with-asd-in-the-schools
#16
Margaret T Floress, Kim Zoder-Martell, Rachel Schaub
A social skills plus relaxation training (SSRT) program was developed using direct training, relaxation training, and reinforcement principles. The aim was to examine the effectiveness of SSRT on increasing the frequency of three target behaviors for one 8-year-old, student classified with autism spectrum disorder (ASD). A multiple-baseline across behaviors design was used to evaluate the effects of SSRT. During baseline, intervention, and maintenance sessions the student's responses were videotaped and then subsequently viewed and coded after the session...
October 17, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29054023/charting-the-territory-describing-the-functional-abilities-of-children-with-progressive-neurological-conditions
#17
Sandy K Tatla, Liisa Holsti, Gail Stephanie Andrews, Leanne Feichtinger, Rose Steele, Harold Siden
AIMS: Little is known about the functional abilities of children with progressive genetic, metabolic, or neurological conditions (PNCs). In this study, children with PNCs were followed over a 2-year period to assess their functional abilities over time. Specific aims were to: 1) describe the changes in functional skills and the effects of age for children with PNCs, 2) assess changes in these children's need for caregiver assistance over time, and 3) examine relationships between these children's functional skills and need for caregiver assistance...
October 17, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29054015/synergistic-effect-of-copper-and-arsenic-upon-oxidative-stress-inflammation-and-autophagy-alterations-in-brain-tissues-of-gallus-gallus
#18
Xiao Sun, Jinglun Li, Hongjing Zhao, Yu Wang, Juanjuan Liu, Yizhi Shao, Yuan Xue, Mingwei Xing
Arsenic or copper is one of the most highly toxic pollution that can cause dysfunction to brains, however, the exact mechanism remains unclear. The aim of the study is to investigate the mechanisms of arsenic or/and copper-induced oxidative stress, inflammation and autophagy in chicken brains and elucidate the interactions between arsenic and copper. A total of 72 1-day-old Hy-line chickens were divided into four groups (18 chickens per group) treated with 30mg/kg arsenic trioxide (As2O3) or/and 300mg/kg copper sulfate (CuSO4) for 12weeks...
October 12, 2017: Journal of Inorganic Biochemistry
https://www.readbyqxmd.com/read/29053986/metacognitions-in-smoking-evidence-from-a-cross-cultural-validation-of-the-metacognitions-about-smoking-questionnaire-in-a-turkish-sample
#19
Leyla Alma, Marcantonio M Spada, Bruce A Fernie, Adviye Esin Yilmaz-Samanci, Gabriele Caselli, Ana V Nikčević
Metacognitions about the positive and negative effects of smoking have been associated with cigarette use and nicotine dependence. The aim of the present study was to validate the Turkish version of the Metacognitions about Smoking Questionnaire (MSQ; Nikčević et al., 2015). The sample consisted of 859 self-declared smokers (452 female) aged between 18 and 68 years (mean = 28.3; SD = 7.9). Once the English to Turkish translation of the MDQ was completed, confirmatory factor analyses were conducted based on the four-factor structure of the original measure...
October 8, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29053983/conceptualizing-trust-in-community-academic-research-partnerships-using-concept-mapping-approach-a-multi-ctsa-study
#20
Gaurav Dave, Leah Frerichs, Jennifer Jones, Mimi Kim, Jennifer Schaal, Stefanie Vassar, Deepthi Varma, Catherine Striley, Corrine Ruktanonchai, Adina Black, Jennifer Hankins, Nakita Lovelady, Crystal Cene, Melissa Green, Tiffany Young, Shristi Tiwari, Ann Cheney, Linda Cottler, Greer Sullivan, Arleen Brown, Jessica Burke, Giselle Corbie-Smith
OBJECTIVES: Collaborations between communities, healthcare practices and academic institutions are a strategy to address health disparities. Trust is critical in the development and maintaining of effective collaborations. The aim of this pilot study was to engage stakeholders in defining determinants of trust in community academic research partnerships and to develop a framework for measuring trust. METHODS: The study was conducted by five collaborating National Institute of Health' Clinical and Translational Sciences Awardees...
October 12, 2017: Evaluation and Program Planning
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