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https://www.readbyqxmd.com/read/29929215/hypercrosslinked-polymeric-restricted-access-materials-for-analysis-of-biological-fluids
#1
Alekxander Popov, Zinaida K Blinnikova, Maria P Tsyurupa, Vadim A Davankov
New restricted access materials based on microporous hypercrosslinked polystyrene have been developed. The materials are aimed at the use as packings for solid-phase extraction cartridges to isolate low-molecular-weight analytes from biological fluids (for instance, blood plasma or serum). Two features distinguish these polymers from all known restricted access materials. The first one consists in that the microporous hypercrosslinked polystyrene not only exclude proteins from the sorbent phase but also do not adsorb them on the bead outer surface and so they do not cause coagulation of blood protein components...
June 21, 2018: Journal of Separation Science
https://www.readbyqxmd.com/read/29929204/sport-participation-and-metabolic-risk-during-adolescent-years-a-structured-equation-model
#2
AndréOliveira Werneck, Danilo Rodrigues Pereira da Silva, Rômulo Araújo Fernandes, EnioRicardoVaz Ronque, Manuel J Coelho-E-Silva, Edilson Serpeloni Cyrino
Sports practice during childhood can influence health indicators in later ages through direct and indirect pathways. Thus, this study aimed to test direct and indirect pathways to the association between sports practice in childhood and metabolic risk in adolescence, adopting physical activity, adiposity, and cardiorespiratory fitness at adolescence as potential mediators. This cross-sectional study with retrospective information was conducted with 991 adolescents (579 girls, 412 boys) aged 10 to 16 y. Sports activity was self-reported in childhood (retrospective data) and physical activity evaluated in adolescence through questionnaires...
June 21, 2018: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/29929202/-potential-benchmarks-for-successful-interdisciplinary-collaboration-projects-in-germany-a-systematic-review
#3
Marina Weißenborn, Martin Schulz, Manuel Kraft, Walter E Haefeli, Hanna M Seidling
AIM OF THE STUDY: Collaboration between general practitioners and community pharmacists is essential to ensure safe and effective patient care. However, collaboration in primary care is not standardized and varies greatly. This review aims to highlight projects about professional collaboration in ambulatory care in Germany and identifies promising approaches and successful benchmarks that should be considered for future projects. METHODS: A systematic literature search was performed based on the PRISMA guidelines to identify articles focusing on professional collaboration between general practitioners and pharmacists...
June 21, 2018: Das Gesundheitswesen
https://www.readbyqxmd.com/read/29929197/sleep-disordered-breathing-in-children-with-rare-skeletal-disorders-a-survey-of-clinical-records
#4
Marco Zaffanello, Giorgio Piacentini, Luca Sacchetto, Angelo Pietrobelli, Emma Gasperi, Marco Barillari, Nicolò Cardobi, Luana Nosetti, Diego Ramaroli, Franco Antoniazzi
OBJECTIVE: Craniofacial disharmony in skeletal diseases is strongly associated with sleep-disordered breathing. Our aim was to study sleep respiratory patterns in young children with rare skeletal disorders. DESIGN: This retrospective study included children with achondroplasia, osteogenesis imperfecta and Ellis van Creveld Syndrome. Our subjects underwent an in-laboratory overnight respiratory polygraph between January 2012 and April 2016. All medical records were reviewed and brain Magnetic Resonance Imaging was conducted on patients with achondroplasia, nasopharynx, oropharynx and laryngopharynx spaces...
June 21, 2018: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/29929182/long-term-evaluation-of-community-health-promotion-using-capacity-building-as-an-intermediate-outcome-measure
#5
S Nickel, W Süß, C Lorentz, A Trojan
OBJECTIVES: Between 2001 and 2012, the health authority of Hamburg-Eimsbüttel carried out a health promotion programme for children and their parents in a disadvantaged neighbourhood called Lenzsiedlung. The programme consisted of different action fields aiming at sustainable establishment of community capacities. STUDY DESIGN: The research goal was the long-term assessment of community capacities with a newly developed instrument 'KEQ' (KEQ = Kapazitätsentwicklung im Quartier/capacity building in small areas/neighbourhoods)...
June 18, 2018: Public Health
https://www.readbyqxmd.com/read/29929178/the-occurrence-transmission-virulence-and-antibiotic-resistance-of-listeria-monocytogenes-in-fish-processing-plant
#6
Krzysztof Skowron, Joanna Kwiecińska-Piróg, Katarzyna Grudlewska, Agnieszka Świeca, Zbigniew Paluszak, Justyna Bauza-Kaszewska, Ewa Wałecka-Zacharska, Eugenia Gospodarek-Komkowska
The aim of this research was to investigate the occurrence of Listeria monocytogenes in fish and fish processing plant and to determine their transmission, virulence and antibiotic resistance. L. monocytogenes was isolated according to the ISO 11290-1. The identification of L. monocytogenes was confirmed by multiplex PCR method. Genetic similarity of L. monocytogenes strains was determined with the Pulsed-Filed Gene Electrophoresis (PFGE) method. The multiplex PCR was used for identification of L. monocytogenes serogroups and detection of selected virulence genes (actA, fbpA, hlyA, iap, inlA, inlB, mpl, plcA, plcB, prfA)...
June 13, 2018: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/29929176/mechanisms-of-antimelanoma-effect-of-oat-%C3%AE-glucan-supported-by-electroporation
#7
Anna Choromanska, Sandra Lubinska, Anna Szewczyk, Jolanta Saczko, Julita Kulbacka
There are still not specified mechanisms how beta-glucan molecules are transported into cells. Supposing, beta-glucan toxicity against tumor cells may be related to the overexpression of the transporter responsible for the transport of glucose molecules in the cells. In this case, glucans - polymers composed of glucose units are much more up-taken by tumor than normal cells. Increased GLUT1 (Glucose Transporter Type 1) expression has been demonstrated earlier in malignant melanomas. GLUT1 expression promotes glucose uptake and cell growth in that cells...
June 6, 2018: Bioelectrochemistry
https://www.readbyqxmd.com/read/29929169/ultrasound-guided-posterior-quadratus-lumborum-block-for-postoperative-pain-after-laparoscopic-cholecystectomy-a-randomized-controlled-double-blind-study
#8
Korgün Ökmen, Burcu Metin Ökmen, Serra Topal
STUDY OBJECTIVE: Laparoscopic techniques are commonly used in surgical operations of the gallbladder. There are very few regional anesthesia methods used to achieve this goal. We aimed to investigate the effect of ultrasound-guided posterior quadratus lumborum block (QLB), administered bilaterally on pain scores after laparoscopic cholecystectomy operations. DESIGN: Prospective, double blind, randomized controlled clinical trial. SETTING: Single-institution, tertiary hospital...
June 18, 2018: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/29929162/in-vivo-validation-of-patellofemoral-kinematics-during-overground-gait-and-stair-ascent
#9
Samuel Pitcairn, Bryson Lesniak, William Anderst
BACKGROUND: The patellofemoral (PF) joint is a common site for non-specific anterior knee pain. The pathophysiology of patellofemoral pain may be related to abnormal motion of the patella relative to the femur, leading to increased stress at the patellofemoral joint. Patellofemoral motion cannot be accurately measured using conventional motion capture. RESEARCH QUESTION: The aim of this study was to determine the accuracy of a biplane radiography system for measuring in vivo PF motion during walking and stair ascent...
June 18, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29929161/do-spatiotemporal-parameters-and-gait-variability-differ-across-the-lifespan-of-healthy-adults-a-systematic-review
#10
REVIEW
Nolan Herssens, Evi Verbecque, Ann Hallemans, Luc Vereeck, Vincent Van Rompaey, Wim Saeys
BACKGROUND: Aging is often associated with changes in the musculoskeletal system, peripheral and central nervous system. These age-related changes often result in mobility problems influencing gait performance. Compensatory strategies are used as a way to adapt to these physiological changes. RESEARCH QUESTION: The aim of this review is to investigate the differences in spatiotemporal and gait variability measures throughout the healthy adult life. METHODS: This systematic review was conducted according to the PRISMA guidelines and registered in the PROSPERO database (no...
June 12, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29929159/methodological-factors-influencing-inhalation-bioaccessibility-of-metal-loid-s-in-pm-2-5-using-simulated-lung-fluid
#11
Farzana Kastury, E Smith, Ranju R Karna, Kirk G Scheckel, A L Juhasz
In this study, methodological factors influencing the dissolution of metal(loid)s in simulated lung fluid (SLF) was assessed in order to develop a standardised method for the assessment of inhalation bioaccessibility in PM2.5 . To achieve this aim, the effects of solid to liquid (S/L) ratio (1:100 to 1:5000), agitation (magnetic agitation, occasional shaking, orbital and end-over-end rotation), composition of SLF (artificial lysosomal fluid: ALF; phagolysosomal simulant fluid: PSF) and extraction time (1-120 h) on metal(loid) bioaccessibility were investigated using PM2...
June 7, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29929153/pain-and-anxiety-and-their-relationship-with-medication-doses-in-the-intensive-care-unit
#12
Sunyoung Park, Se Hee Na, Jooyoung Oh, Jong Seok Lee, Seung-Taek Oh, Jae-Jin Kim, Jin Young Park
PURPOSE: Pain and anxiety are understudied despite their importance to the general medical condition. The aim of the present study was to examine the effects of pain and anxiety and their relationship to the doses of opioids and anxiolytics administered in intensive care unit (ICU) patients. METHODS: The subjects included 1349 conscious, critically ill patients admitted to an ICU. Psychiatrists evaluated the patients daily for pain and anxiety. Data regarding the doses of opioids and benzodiazepines administered were gathered...
June 2, 2018: Journal of Critical Care
https://www.readbyqxmd.com/read/29929151/the-challenges-and-opportunities-of-climate-change-policy-under-different-stages-of-economic-development
#13
Genovaitė Liobikienė, Mindaugas Butkus
Climate change policy confronts with many challenges and opportunities. Thus the aim of this study was to analyse the impact of gross domestic product (hereinafter GDP), trade, foreign direct investment (hereinafter FDI), energy efficiency (hereinafter EF) and renewable energy (hereinafter RE) consumption on greenhouse gas (hereinafter GHG) emissions in 1990-2013 and reveal the main challenges and opportunities of climate policy for which policy makers should take the most attention under different stages of economic development...
June 18, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29929132/association-of-genetic-polymorphisms-of-telomere-binding-proteins-with-cholinesterase-activity-in-omethoate-exposed-workers
#14
Mingcui Ding, Yongli Yang, Xiaoran Duan, Sihua Wang, Xiaolei Feng, Tuanwei Wang, Pengpeng Wang, Suxiang Liu, Lei Li, Junling Liu, Lixia Tang, Xinhua Niu, Yuhong Zhang, Guoyu Li, Wu Yao, Liuxin Cui, Wei Wang
Omethoate, an organophosphorous pesticide, can cause a variety of health effects, especially the decrease of cholinesterase activity. The aim of this study is to explore the association of genetic polymorphisms of telomere binding proteins with cholinesterase activity in omethoate-exposed population. Cholinesterase activities in whole blood, red blood cell and plasma were detected using acetylthiocholine and dithio-bis-(nitrobenzoic acid) method; Genetic Genotyping of POT1 rs1034794, POT1 rs10250202, TERF1 rs3863242 and TERT rs2736098 were performed with PCR-RFLP...
June 18, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29929125/influence-of-titanium-dioxide-nanoparticles-on-the-toxicity-of-arsenate-in-nannochloropsis-maritima
#15
Fan Yang, Changzhou Yan
Interest is growing in the role that nanoparticles play in modifying the biological effects of contaminants. This study aimed to determine whether nano-TiO2 exhibited pronounced influence on arsenate (As(V)) toxicity levels to the marine microalgae Nannochloropsis maritima. We compared individual and combined toxicity levels of As(V) and nano-TiO2 by assessing the inhibition percentages of algal growth. Compared to groups treated with As(V) alone, an EC50 of 53.0 mg/L decreased by 28.8% after the addition of nanoparticles...
June 13, 2018: Chemosphere
https://www.readbyqxmd.com/read/29929122/de-novo-transcriptome-assembly-and-differential-gene-expression-analysis-of-the-calanoid-copepod-acartia-tonsa-exposed-to-nickel-nanoparticles
#16
Chao Zhou, Ylenia Carotenuto, Valentina Vitiello, Changwen Wu, Jianshe Zhang, Isabella Buttino
The calanoid copepod Acartia tonsa is a reference species in standardized ecotoxicology bioassay. Despite this interest, there is a lack of knowledge on molecular responses of A. tonsa to contaminants. We generated a de novo assembled transcriptome of A. tonsa exposed 4 days to 8.5 and 17 mg/L nickel nanoparticles (NiNPs), which have been shown to reduce egg hatching success and larval survival but had no effects on the adults. Aims of our study were to 1) improve the knowledge on the molecular responses of A...
June 14, 2018: Chemosphere
https://www.readbyqxmd.com/read/29929121/influence-of-salinity-on-the-toxicity-of-silver-nanoparticles-agnps-and-silver-nitrate-agno-3-in-halophilic-microalgae-dunaliella-salina
#17
Seyed Ali Johari, Mehrdad Sarkheil, Mohammad Behzadi Tayemeh, Shakila Veisi
This study aim to evaluate the potential toxic effects of citrate coated silver nanoparticles (AgNPs) and ionic silver (AgNO3 ) on marine microalgae Dunaliella salina under three different salinities (35, 70, and 140 g/L). The toxicity was investigated according to modified OECD guideline (No. 201) by 72 h exposure of microalgae to various concentrations of each of the chemicals in Walne's saline media. According to the results, the growth inhibitory effects of AgNPs and AgNO3 increased significantly coincidence with increasing time and concentration compared to control (P < 0...
June 13, 2018: Chemosphere
https://www.readbyqxmd.com/read/29929113/predicting-suicidal-behaviour-after-first-episode-of-non-affective-psychosis-the-role-of-neurocognitive-functioning
#18
M Canal-Rivero, J D López-Moríñigo, E Setién-Suero, M Ruiz-Veguilla, J L Ayuso-Mateos, R Ayesa-Arriola, B Crespo-Facorro
BACKGROUND: Suicide has been recognised as one of the major causes of premature death in psychosis. However, predicting suicidal behaviour (SB) is still challenging in the clinical setting and the association of neurocognition with SB in psychosis remains poorly understood. This study aimed to investigate the role of neurocognitive performance as predictor of SB. Also, we sought to explore differences in the evolution of clinical and neurocognitive functioning between participants with/without history of suicide attempts (SA) over follow-up period...
June 18, 2018: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29929111/calcification-in-cerebral-parenchyma-affects-pharmacoresistant-epilepsy-in-tuberous-sclerosis
#19
Meng-Na Zhang, Li-Ping Zou, Yang-Yang Wang, Ling-Yu Pang, Shu-Fang Ma, Lu-Lu Huang, Yang Gao, Qian Lu, David Neal Franz
PURPOSE: Tuberous sclerosis (TSC) is an autosomal dominant inherited disease caused by mutations in the TSC1 or TSC2 gene and results in the over-activation of the mammalian target of the rapamycin (mTOR) signaling pathway. Rapamycin, an mTOR inhibitor, is clinically used to treat hamartomatous lesionsas in TSC and its effect on controlling epilepsy is also reported in many studies. This study aims to evaluate the risk factors of pharmacoresistant epilepsy in patients with TSC receiving long-term rapamycin treatment...
June 15, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29929106/acetyl-assisted-autohydrolysis-of-sugarcane-bagasse-for-the-production-of-xylo-oligosaccharides-without-additional-chemicals
#20
Weiwei Zhang, Yanzhi You, Fuhou Lei, Pengfei Li, Jianxin Jiang
The aim of this work was to study acetyl-assisted autohydrolysis of sugarcane bagasse for the production of xylo-oligosaccharides without additional chemicals. A xylo-oligosaccharide yield of 50.35% was obtained in 10 min through sugarcane bagasse autohydrolysis at 200 °C; this yield was 49.64% after acetyl-assisted autohydrolysis of a 65:35 mixture of sugarcane bagasse/white birch at 160 °C for 100 min. The yield of xylo-oligosaccharides was close to that obtained at 180 °C/40 min and 200 °C/10 min through the autohydrolysis of sugarcane bagasse...
June 14, 2018: Bioresource Technology
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